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231 results on '"Kaiser, Eric"'

2. Flow-Sizing Critical Care Resources*

Author

Nates, Joseph L., Oropello, John M., Badjatia, Neeraj, Beilman, Gregory, Coopersmith, Craig M., Halpern, Neil A., Herr, Daniel L., Jacobi, Judith, Kahn, Roozehra, Leung, Sharon, Puri, Nitin, Sen, Ayan, Pastores, Stephen M., Angus, Derek C., Baker, Andrew, Brown, Daniel R., Buchman, Timothy S., Christman, John W., Cobb, J. Perren, D’Agostino, Rhonda, Diaz-Gomez, Jose, Doig, Christopher, Farmer, J. Christopher, Galvagno, Samuel M., Gasperino, James, Gregg, Sara R., Kaiser, Eric, Kapu, April N., Khouli, Hassan, Kohli-Seth, Roopa, Laussen, Peter, Lilly, Craig M., Marinaro, Jon, Masur, Henry, Mehta, Gargi, Melander, Sheila, Moore, Jason, Popovich, Marc, Price, Kristen, Rahmanian, Marjan, and Sessler, Curtis

Published
2023
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3. A measure of the blink reflex to parametric variation of mechanical stimulation of the trigeminal nerve.

Author

Kaiser, Eric A., Haggerty, Edda B., Garner, Dena P., Bunya, Vatinee Y., and Aguirre, Geoffrey K.

Subjects
*BLINKING (Physiology), *TRIGEMINAL nerve, *NEURAL stimulation, *STIMULUS intensity, *INDIVIDUAL differences, *ATTENTIONAL blink, *EYELIDS
Abstract

The primary goal of this study was to develop a parametric model that relates variation in stimulation of the trigeminal nerve to properties of the blink response. We measured blink responses in 17 healthy, adult participants to air puffs directed at the lateral canthus of the eye at five different, log‐spaced intensities (3.5–60 PSI). Lid position over time was decomposed into amplitude and velocity components. We found that blink amplitude was systematically related to log stimulus intensity, with the relationship well described by a sigmoidal function. The parameters of the model fit correspond to the slope of the function and the stimulus intensity required to produce half of a maximal blink response (the half‐response threshold). There was a reliable increase in the half‐response threshold for the contralateral as compared to the ipsilateral blink response. This increase was consistent across participants despite substantial individual differences in the half‐response threshold and slope parameters of the overall sensitivity function, suggesting that the laterality effect arises in the neural circuit subsequent to individual differences in sensitivity. Overall, we find that graded mechanical stimulation of the somatosensory trigeminal afferents elicits a graded response that is well described by a simple parametric model. We discuss the application of parametric measurements of the blink response to the detection of group differences in trigeminal sensitivity. There has been limited study of how variation in stimulus intensity influences the cutaneous blink response. We describe how variation in the intensity of an air puff stimulus relates to the amplitude of the blink response using a two‐parameter model. The parameters of the model capture individual differences in response, which may be used in future studies to identify population differences in trigeminal sensitivity. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Effect of CGRP inhibitors on interictal cerebral hemodynamics in individuals with migraine.

Author

Carter, Sarah C., Cucchiara, Brett, Reehal, Navpreet, Hamilton, Katherine, Kaiser, Eric A., and Favilla, Christopher G.

Subjects
HEMODYNAMICS, CALCITONIN gene-related peptide, POSTERIOR cerebral artery, MIGRAINE, CEREBRAL circulation
Abstract

Introduction: Calcitonin gene-related peptide (CGRP) plays an important role in cerebral vasodilation, so here we aim to quantify the impact of CGRP monoclonal antibody (mAb) therapy on cerebral hemodynamics. Methods: In 23 patients with chronic and episodic migraine, cerebral hemodynamic monitoring was performed (1) prior to and (2) 3-months into CGRP-mAb therapy. Transcranial Doppler monitored cerebral blood flow velocity (CBFv) in the middle cerebral artery (MCA) and posterior cerebral artery (PCA), from which cerebrovascular reactivity (CVR) and cerebral autoregulation (CA; Mx-index) were calculated. Results: CA was similar off and on treatment, in the MCA (p = 0.42) and PCA (p = 0.72). CVR was also unaffected by treatment, in the MCA (p = 0.38) and PCA (p = 0.92). CBFv and blood pressure were also unaffected. The subgroup of clinical responders (>50% reduction in migraine frequency) exhibited a small reduction in MCA-CBFv (6.0cm/s; IQR: 1.1-12.4; p = 0.007) and PCA-CBFv (8.9 cm/s; IQR: 6.9-10.3; p = 0.04). Discussion: Dynamic measures of cerebrovascular physiology were preserved after 3 months of CGRP-mAb therapy, but a small reduction in CBFv was observed in patients who responded to treatment. Subgroup findings should be interpreted cautiously, but further investigation may clarify if CBFv is dependent on the degree of CGRP inhibition or may serve as a biomarker of drug sensitivity. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Role of Calcitonin Gene-Related Peptide on the Gastrointestinal Symptoms of Migraine—Clinical Considerations: A Narrative Review

Author

Ailani, Jessica, primary, Kaiser, Eric A., additional, Mathew, Paul G., additional, McAllister, Peter, additional, Russo, Andrew F., additional, Vélez, Christopher, additional, Ramajo, Angela Pozo, additional, Abdrabboh, Ahmad, additional, Xu, Cen, additional, Rasmussen, Soeren, additional, and Tepper, Stewart J., additional

Published
2022
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25. Radioactivity Induced by a Local Mass Injection Initiated Dense Plasma Focus*

Author

Jackson, Stuart L., primary, Mosher, David, additional, Kaiser, Eric R., additional, Beresnyak, Andrey R., additional, Commisso, Robert J., additional, Adamson, Paul E., additional, Dasgupta, Arati, additional, Schumer, Joseph W., additional, Groopman, Evan E., additional, Willingham, David G., additional, Klir, Daniel, additional, Rezac, Karel, additional, and Cikhardt, Jakub, additional

Published
2021
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35. Understanding the latest advances in vinyl technology for coatings

Author

Kaufman, Michael, Wu, Wenjun, Kaiser, Eric, and Miller, Chris

Subjects
Business, Chemicals, plastics and rubber industries
Abstract

In the past 50 years, coatings technology has evolved at a rapid pace. As demand, performance requirements and environmental regulations have changed, so has the industry. Some things, however, have [...]

Published
2011

40. Supplemental Material1 - Supplemental material for A web-based, branching logic questionnaire for the automated classification of migraine

Author

Kaiser, Eric A, Igdalova, Aleksandra, Aguirre, Geoffrey K, and Cucchiara, Brett

Subjects
FOS: Psychology, FOS: Clinical medicine, 170199 Psychology not elsewhere classified, 110319 Psychiatry (incl. Psychotherapy), 110306 Endocrinology, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, Supplemental Material1 for A web-based, branching logic questionnaire for the automated classification of migraine by Eric A Kaiser, Aleksandra Igdalova, Geoffrey K Aguirre and Brett Cucchiara in Cephalalgia

Published
2019
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41. Colaboradores

Author

Aamodt, Whitley, Aradi, Stephen, Bae, Charles J., Balu, Ramani, Bassiri, Hamid, Best, John, Cai, Alice, Cantor, Charles, Caylor, Meghan M., Cherayil, Neena, Cincotta, Molly, Conrad, Erin, Coslett, H. Branch, Coughlin, David, Cristancho, Daniel, Cucchiara, Brett L., Deik, Andres, Douglas, Anne G., Edmundson, Christyn, Esenwa, Charles, Favilla, Christopher G., Fuentes, Andrea, Gelfand, Michael, George, Donna, Gehrman, Philip, Gill, Alexander J., Gomez, Francisco, Grossman, Murray, Hamedani, Ali G., Hamilton, Katherine, Humbert, Kelley A., Ishida, Koto, Ji, Jonathan, Kaiser, Eric, Kalanuria, Atul, Khankhanian, Pouya, Klein, Joshua P., Kolson, Dennis L., Konsky, Glenn, Kritikos, Michael E., Kumar, Monisha A., Kung, David, Lancaster, Eric, Lee, Angelica Maria, Levine, Joshua M., Levinson, Noah, Liberman, Ava, Machemehl, Hannah, Mahanna-Gabrielli, Elizabeth, McGarvey, Michael, Mendizabal, Adys, Messé, Steven R., Mir, Saad, Moyer, Megan T., Mullen, Michael, Nathan, Cody, Novello, Paul J., Oehlke, Jessica, O’Kula, Susanna, Patterson-Gentile, Carlyn, Perrone, Christopher, Price, Raymond S., Pukenas, Bryan, Quinn, Colin, Raab, Lindsay, Raizen, David, Ramchand, Preethi, Rasheed, Izad-Yar D., Recober, Ana, Renner, Christopher, Rosen, Ilene M., Rosenberg, Jon, Sandsmark, Danielle K., Sherma, Arun K., Stein, Laura A., Tizazu, Etsegenet F., Torres, Jose, Walia, Jessy, Williamson, Eric, and Wolk, David

Published
2022
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