803 results on '"Kanaar, Roland"'
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2. Proof-of-concept study linking ex vivo sensitivity testing to neoadjuvant anthracycline-based chemotherapy response in breast cancer patients
3. Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability
4. Increased vascular smooth muscle cell senescence in aneurysmal Fibulin-4 mutant mice
5. Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure
6. Multi-scale cellular imaging of DNA double strand break repair
7. Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests
8. Functional analysis of cell lines derived from SMAD3-related Loeys-Dietz syndrome patients provides insights into genotype-phenotype relation
9. Distinct mobility patterns of BRCA2 molecules at DNA damage sites.
10. DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces.
11. Functional analysis of cell lines derived from SMAD3-related Loeys-Dietz syndrome patients provides insights into genotype-phenotype relation.
12. Functional analysis of cell lines derived from SMAD3-related Loeys-Dietz Syndrome patients provides insights into genotype-phenotype relations
13. BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination
14. BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination
15. Chromosome Pairing Through Tensioned DNA Tethers Revealed by BRCA2 Meiotic Domain Deletion
16. DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces
17. Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2 -Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.
18. BRCA2-HSF2BP oligomeric ring assembly is implicated in the regulation of homologous recombination during meiosis
19. EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY
20. R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response
21. Involvement of Mammalian Mus81 in Genome Integrity and Tumor Suppression
22. Dynamics of DNA Double-Strand Breaks Revealed by Clustering of Damaged Chromosome Domains
23. Supplementary Data from A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture
24. Data from A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture
25. Supplemental legend from Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects
26. Figure S3 from Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects
27. Table S1, Table S2, Table S3 from Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects
28. Supplementary Figure Legend from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
29. Supplementary Figure 2 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
30. Data from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
31. Supplementary Figure 5 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
32. Supplementary Figure 6 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
33. Supplementary Figure 1 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
34. Supplementary Methods from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
35. Supplementary Figure 4 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
36. Supplementary Figure 7 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
37. Supplementary Figure 3 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
38. The Coiled-Coil of the Human Rad50 DNA Repair Protein Contains Specific Segments of Increased Flexibility
39. Disruption of Maternal DNA Repair Increases Sperm-Derived Chromosomal Aberrations
40. Growth Inhibition and DNA Damage Induced by Cre Recombinase in Mammalian Cells
41. Absence of Interdomain Contacts in the Crystal Structure of the RNA Recognition Motifs of Sex-Lethal
42. Genome editing by natural and engineered CRISPR-associated nucleases
43. Distinct mobility patterns of BRCA2 molecules at DNA damage sites
44. Mutations in the Small Subunit of the Drosophila U2AF Splicing Factor Cause Lethality and Developmental Defects
45. Single-Molecule Dynamics and Localization of DNA Repair Proteins in Cells
46. DNA damage response and anti-apoptotic proteins predict radiosensitization efficacy of HDAC inhibitors SAHA and LBH589 in patient-derived glioblastoma cells
47. Evaluation of the Heat Shock Protein 90 Inhibitor Ganetespib as a Sensitizer to Hyperthermia-Based Cancer Treatments
48. Abstract 805: RECAP (REpair CAPacity) identifies a subset of breast cancers unable to form RAD51 foci which are undetected by DNA-based BRCAness tests
49. Microscopy-based single-cell proteomic profiling reveals heterogeneity in DNA damage response dynamics
50. Structure and cell biology of the vessel wall
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