13,635 results on '"Kang, H."'
Search Results
2. Estimation of Spatial Channel Model in a Wireless Ultra-Wide-Area Backhaul Network using the Deterministic Ray Tube Method
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YUN, D., KIM, Y., JUNG, I., JUNG, H., and KANG, H.
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channel models ,microwave propagation ,mobile communication ,ray tracing ,statistical analysis ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Computer engineering. Computer hardware ,TK7885-7895 - Abstract
This paper presents an analysis of channel characteristics in a wireless ultra-wide-area backhaul network based on deterministic ray tube (DRT) ray tracing. The accurate knowledge of spatial temporal channel characteristics enables system-level simulations of wireless communication systems. However, few papers have been published on the analysis of channel characteristics in an ultra-wide-area backhaul network, which is one of a promising fifth generation (5G) scheme. In this paper, we conduct an analysis of the outdoor propagation environment using the DRT ray tracing. Spatial temporal channel parameters are then calculated using linear regression and multipath clustering algorithm. The proposed analysis scheme is verified by comparing the results of existing scenario with the reference spatial channel model (SCM) parameters. Channel characteristics in the wireless ultra-wide-area backhaul scenarios are then investigated.
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- 2019
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3. Different tumor growth pattern of clinically nonfunctioning pituitary neuroendocrine tumor according to sex and age: a longitudinal study
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Park, S. S., Kang, H., Kim, Y. H., and Kim, J. H.
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- 2024
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4. A New Method for Maintaining Constant Dither Amplitude in Low Frequency PWM
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KANG, H., PARK, J., CHO, J., KIM, J., and OH, J.
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pulse width modulation ,circuit simulation ,driver circuits ,solenoids ,mathematical analysis ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Computer engineering. Computer hardware ,TK7885-7895 - Abstract
Various controls for fluid flow and pressure are now required in related industries, and the pulse width modulation (PWM) and dithering techniques have become essential for the proportional control of solenoids. However, there is a fatal drawback when the dither current signals are generated as a by-product of low frequency PWM. That is, the average current and the dither amplitude in low frequency PWM cannot be controlled independently. Therefore, a new method for maintaining constant dither amplitudes is proposed in this paper. Throughout the mathematical analysis, the effect of PWM frequency and duty cycle on the average current and dither amplitude was investigated, and the analysis result was validated by electrical experiments. Based on the mathematical analysis, a new method that properly varies both the duty cycle and the PWM frequency to obtain the desired average current and constant dither amplitude was established and verified. This method requires only the calculations for determining the proper PWM frequency and duty cycle, so it is possible to improve the performance of a proportional solenoid valve without additional devices or cost.
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- 2017
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5. Nanomedicines Targeting Ferroptosis to Treat Stress-Related Diseases
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Kang H, Meng F, Liu F, Xie M, Lai H, Li P, and Zhang X
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ferroptosis ,stress-related diseases ,lipid peroxidation ,nanoparticles ,nanomedicine ,targeted therapy. ,Medicine (General) ,R5-920 - Abstract
Hao Kang,1,2,* Fansu Meng,3,* Fengjie Liu,4 Mengjie Xie,4 Haibiao Lai,3 Pengfei Li,5 Xingwang Zhang4 1Department of Medicinal Chemistry and Pharmaceutical Analysis, Anhui College of Traditional Chinese Medicine, Wuhu, People’s Republic of China; 2Wuhu Modern Technology Research and Development Center of Chinese Medicine and Functional Food, Wuhu, People’s Republic of China; 3Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan, People’s Republic of China; 4Department of Pharmaceutics, College of Pharmacy, Jinan University, Guangzhou, People’s Republic of China; 5Department of Oncology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Haibiao Lai; Xingwang Zhang, Email lhb8829@163.com; zhangxw@jnu.edu.cnAbstract: Ferroptosis, a unique form of regulated cell death driven by iron-dependent lethal lipid peroxidation, is implicated in various stress-related diseases like neurodegeneration, vasculopathy, and metabolic disturbance. Stress-related diseases encompass widespread medical disorders that are influenced or exacerbated by stress. These stressors can manifest in various organ or tissue systems and have significant implications for human overall health. Understanding ferroptosis in these diseases offers insights for therapeutic strategies targeting relevant pathways. This review explores ferroptosis mechanisms, its role in pathophysiology, its connection to stress-related diseases, and the potential of ferroptosis-targeted nanomedicines in treating conditions. This monograph also delves into the engineering of ferroptosis-targeted nanomedicines for tackling stress-related diseases, including cancer, cardia-cerebrovascular, neurodegenerative, metabolic and inflammatory diseases. Anyhow, nanotherapy targeting ferroptosis holds promise by both promoting and suppressing ferroptosis for managing stress-related diseases.Keywords: ferroptosis, stress-related diseases, lipid peroxidation, nanoparticles, nanomedicine, targeted therapy
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- 2024
6. The Potential of the lncRNAs ADAMTSL4-AS1, AC067931 and SOCS2-AS1 in Peripheral Blood Mononuclear Cells as Novel Diagnostic Biomarkers for Hepatitis B Virus-Associated Hepatocellular Carcinoma
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Guan W, Zhang C, Miao T, Dong C, Li L, Yuan X, Zhao D, Ai R, Zhang X, Sun M, Kang H, and Nan Y
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adamtsl4-as1 ,ac067931 ,socs2-as1 ,hbv-associated hcc ,diagnostic biomarkers ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Weiwei Guan,1,2 Congyue Zhang,1 Tongguo Miao,1 Chen Dong,1 Lu Li,1 Xiwei Yuan,1 Dandan Zhao,1 Rong Ai,1 Xiaoxiao Zhang,1 Mengjiao Sun,1 Haiyan Kang,2,* Yuemin Nan1,* 1Department of Traditional and Western Medical Hepatology, Hebei Medical University Third Hospital & Hebei International Joint Research Center for Liver Cancer Molecular Diagnosis, Hebei International Science and Technology Cooperation Base, Shijiazhuang, Hebei Province, 050051, People’s Republic of China; 2Department of Liver Disease, The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, Hebei, 050023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuemin Nan, Department of Traditional and Western Medical Hepatology, Hebei Medical University Third Hospital & Hebei International Joint Research Center for Liver Cancer Molecular Diagnosis, Hebei International Science and Technology Cooperation Base, No. 139, Ziqiang Road, Shijiazhuang, Hebei Province, 050051, People’s Republic of China, Tel +86 18533112266, Email nanyuemin@163.com Haiyan Kang, Department of Liver Disease, The Fifth Hospital of Shijiazhuang, Hebei Medical University, No. 42, Tanan Road, Shijiazhuang, Hebei Province, 050023, People’s Republic of China, Tel +86 13315952782, Email kanghaiyan1976@126.comPurpose: Long noncoding RNAs (lncRNAs) might be closely associated with hepatocellular carcinoma (HCC) progression and could serve as diagnostic and prognostic markers. This study aimed to investigate lncRNA-based diagnostic biomarkers for hepatitis B virus (HBV)-associated HCC.Materials and Methods: High‐throughput transcriptome sequencing was conducted on the liver tissues of 15 patients with HBV-associated liver diseases (5 with chronic hepatitis B [CHB], 5 with liver cirrhosis [LC], and 5 with HCC). Quantitative real-time polymerase chain reaction (qRT-PCR) was used to analyze lncRNA expressions. Potential diagnostic performance for HBV-associated HCC screening was evaluated.Results: Through trend analysis and functional analysis, we found that 8 lncRNAs were gradually upregulated and 1 lncRNA was progressively downregulated by regulation of target mRNAs and downstream HCC-associated signaling pathways. The validation of dysregulated lncRNAs in peripheral blood mononuclear cells (PBMCs) and HCC tissues by qRT-PCR revealed that ADAMTSL4-AS1, SOCS2-AS1, and AC067931 were significantly increased in HCC compared with CHB and cirrhosis. Moreover, differentially expressed lncRNAs were aberrantly elevated in Huh7, Hep3B, HepG2, and HepG2.215 cells compared with LX2 cells. Furthermore, ADAMTSL4-AS1, SOCS2-AS1, and AC067931 were identified as novel biomarkers for HBV-associated HCC. For distinguishing HCC from CHB, ADAMTSL4-AS1, AC067931, and SOCS2-AS1 combined with alpha-fetoprotein (AFP) had an area under the curve (AUC) of 0.945 (sensitivity, 83.9%; specificity, 89.8%). Similarly, for distinguishing HCC from LC, this combination had an AUC of 0.871 (sensitivity, 91.1%; specificity, 68.2%). Furthermore, this combination showed the highest diagnostic ability to distinguish HCC from CHB and LC (AUC, 0.905; sensitivity, 91.1%; specificity, 75.3%). In particular, this combination identified AFP-negative (AFP < 20 ng/mL) (AUC = 0.814), small (AUC = 0.909), and early stage (AUC = 0.863) tumors.Conclusion: ADAMTSL4-AS1, SOCS2-AS1, and AC067931 combined with AFP in PBMCs may serve as a noninvasive diagnostic biomarker for HBV-associated HCC, especially AFP-negative, small, and early stage HCC.Keywords: ADAMTSL4-AS1, AC067931, SOCS2-AS1, HBV-associated HCC, diagnostic biomarkers
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- 2024
7. Study of the Epidemiological and Mechanistic Differences Between Carbapenem-Resistant Klebsiella pneumoniae Infections in Children and Adults
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Zhou J, Song S, Xue S, Zhu Y, Xu B, Ma P, Lv Y, and Kang H
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children ,adults ,klebsiella pneumoniae ,carbapenemases ,drug resistance mechanisms. ,Infectious and parasitic diseases ,RC109-216 - Abstract
Jiajia Zhou,1,2,* Shuang Song,2,3,* Senlin Xue,2 Yingxing Zhu,3 Boyin Xu,4 Ping Ma,2,3 Yanguan Lv,1 Haiquan Kang2,3 1The Huai’an Maternity and Child Clinical College of Xuzhou Medical University, Huai’an, People’s Republic of China; 2Medical Technology School, Xuzhou Medical University, Xuzhou, People’s Republic of China; 3Department of Clinical Laboratory, Affiliated Hospital of Xuzhou Medical University, Xuzhou, People’s Republic of China; 4Department of Infection Control, Affiliated Hospital of Nantong University, Nantong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Haiquan Kang, Department of Clinical Laboratory, Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, People’s Republic of China, Tel +86-516 85802759, Email hqk811029@163.com Yanguan Lv, The Huai’an Maternity and Child Clinical College of Xuzhou Medical University, Huai’an, 223001, People’s Republic of China, Tel +86-517 89687770, Email lvyanguan@163.comBackground: The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) has garnered international concern due to its significant antibiotic resistance. Notably, children exhibit distinct resistance mechanisms compared to adults, necessitating a differential approach to antibiotic selection. A thorough analysis of CRKP’s epidemiology and drug resistance mechanisms is essential for establishing a robust foundation for clinical anti-infection strategies and precise prevention and control measures.Methods: This study involved the collection of 31 non-repetitive strains from pediatric and adult patients at a tertiary hospital in China, spanning from July 2016 to July 2022, testing for resistance genes, antimicrobial susceptibility, and homology analysis.Results: Infants (0– 1 year) were the largest pediatric CRKP group, with 61.3% of cases. The neonatal intensive care unit (NICU) and pediatrics were the main departments affected. Adults with CRKP had a mean age of 67 years, with the highest prevalence in neurology and emergency ICU. Antimicrobial susceptibility testing revealed that adult CRKP strains exhibited higher resistance to amikacin, ciprofloxacin, cotrimoxazole, and aztreonam compared to pediatric strains. Conversely, pediatric strains showed a higher rate of resistance to ceftazidime/avibactam. The predominant resistance genes identified were blaNDM-5 in children (58.1%) and blaKPC-2 in adults (87.1%), with over 93% of both groups testing positive for extended-spectrum beta-lactamase (ESBL) genes. Multilocus Sequence Typing (MLST) indicated ST2735 and ST11 as the predominant types in children and adults, respectively. Pulsed-field gel electrophoresis (PFGE) identified clonal transmission patterns of ST11 blaKPC-2 and ST15 blaOXA-232 across both age groups. Notably, this study reports the first instance of ST1114-type CRKP co-producing blaNDM-5 and blaOXA-181 in the NICU.Conclusion: This study reveals distinct resistance mechanisms and epidemiology in CRKP from children and adults. The identified clonal transmission patterns emphasize the need for improved infection control to prevent the spread of resistant strains.Keywords: children, adults, Klebsiella pneumoniae, carbapenemases, drug resistance mechanisms
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- 2024
8. Detection and analysis of ship domain parameters in confined waters
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Liu, D.P., primary, Siow, C.-L., additional, Kang, H.-S., additional, and Guedes Soares, C., additional
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- 2024
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9. Hydrothermal Synthesis and Structural Characterization of a Novel Ni(II) Coordination Polymer Based on a Y-shaped Ligand
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Kang, H. X., Fu, Y. Q., and Liu, G. Z.
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- 2023
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10. The Association Between Obesity Measures and Metabolic Syndrome Risk in Korean Adolescents Aged 10–18 Years
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Song M, Kang S, and Kang H
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obesity ,pediatrics ,adolescence ,metabolic syndrome ,risk factors ,Medicine (General) ,R5-920 - Abstract
Munku Song, Seamon Kang, Hyunsik Kang College of Sport Science, Sungkyunkwan University, Suwon, South KoreaCorrespondence: Hyunsik Kang, College of Sport Science, Sungkyunkwan University, Suwon, 16419, South Korea, Tel +82-31-299-6923, Fax +82-31-299-6929, Email hkang@skku.eduIntroduction: Childhood obesity is strongly linked to an increased risk of metabolic syndrome (MetS), type 2 diabetes, and cardiovascular disease in adulthood, endangering the global healthcare system. No single tool for detecting MetS is suitable for all pediatric populations. This study aimed to investigate the association between obesity measures and MetS in Korean children and adolescents.Method and Materials: The data were obtained from 1663 children and adolescents aged 10– 19 years (771 girls) who participated in the Fourth and Fifth Korea National Health and Nutrition Examination Surveys. Body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHtR) were included as obesity measures. Fasting blood glucose, triglycerides, high-density lipoprotein cholesterol, and resting blood pressure were included as metabolic risk factors. MetS was defined as the clustering of metabolic risk factors such as elevated fasting blood glucose, elevated mean arterial pressure, elevated triglycerides, and low high-density lipoprotein cholesterol.Results: Regardless of the obesity measures used, obese children and adolescents were more likely to have a clustering of metabolic risk factors compared to their non-obese counterparts: BMI-based obesity (odds ratio, OR=4.151, 95% confidence interval, CI=2.763~6.238, p< 0.001), WC-based obesity (OR=1.917, 95% CI=1.066~3.446, p=0.010), and WHtR-based obesity (OR=2.160 and 95% CI=1.203~3.878, p=0.003). A receiver operating curve analysis showed that BMI (area under the curve, AUC=0.849, 95% CI=0.8270.871) outperformed WC (AUC=0.833, 95% CI=0.8090.856) and WHtR (AUC=0.794, 95% CI=0.7670.821) in detecting the presence of MetS.Conclusion and Recommendation: Study findings suggest that obese teenagers are more likely to have metabolic syndrome than non-obese teens. Concerning accuracy, convenience, and ease of use and calculation, BMI is the best screening tool for detecting MetS in Korean children and adolescents.Keywords: obesity, pediatrics, adolescence, metabolic syndrome, risk factors
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- 2024
11. Enhancing Surgical Nursing Student Performance: Comparative Study of Simulation-Based Learning and Problem-Based Learning
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Ma L, Yan R, Wang X, Gao X, Fan N, Liu L, and Kang H
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baccalaureate nursing ,education ,problem-based learning ,simulation training ,surgical nursing. ,Medicine (General) ,R5-920 - Abstract
Lihe Ma,1 Rui Yan,1 Xiang Wang,2 Xiaohong Gao,1 Na Fan,1 Linmei Liu,3 Haifen Kang3 1Nursing College of Shanxi Medical University, Taiyuan, People’s Republic of China; 2Department of Foreign Language, Shanxi Medical University, Taiyuan, People’s Republic of China; 3Department of General Surgery, First Affiliated Hospital of Shanxi Medical University, Taiyuan, People’s Republic of ChinaCorrespondence: Rui Yan, Nursing College of Shanxi Medical University, No. 56 of Xinjian Road, Yingze District, Taiyuan, Shanxi, 030001, People’s Republic of China, Tel +86 13934168679, Email yanruifl29@outlook.comBackground: Surgical nursing is a high-risk, high-pressure, and complex field. Nurses need extensive knowledge, skills, and abilities. Problem-Based Learning (PBL) and Simulation-Based Learning (SBL) are effective student-centered methods. Which method is better for surgical nurse training? More research is needed to determine the best approach for undergraduate surgical nurse education.Purpose: To compare the impact of PBL and SBL on undergraduate nursing students’ performance and improve learning outcomes in surgical nursing education.Methods: We used a pretest/post-test design with 318 nursing undergraduates randomly assigned to two groups. Participants completed three progressive scenarios focused on surgical nursing cases. Experts blindly reviewed video recordings using the 70-item Korean Nurses’ Core Competence Scale (KNCCS) to assess performance. The 13-item Satisfaction and Self-confidence in learning Scale (SSS) measured learning confidence and satisfaction. SBL participants also completed the 16-item Educational Practices in Simulation Scale (EPSS) and 20-item Simulation Design Scale (SDS).Results: The study found significant positive effects on both groups, with noticeable improvements in post-test, retention, and follow-up test results (P < 0.001). The SBL group showed higher competency levels in nurses (P < 0.001). The Cohen’s d and effect size (r) for various skills were as follows: clinical performance (0.84767 and 6.39023), critical thinking (0.31017 and 0.15325), professional attitude (0.85868 and 0.39452), and communication skills (1.55149 and 0.61294). The satisfaction and self-confidence of nurses were higher in the SBL group (4.53± 0.596; 4.47± 0.611) compared to the PBL group (4.32± 0.689; 4.25± 0.632) in all dimensions of SSS (all P < 0.05). The SBL group also scored high in simulation design and EPSS. However, improvements are needed in fidelity, objectives, information, and students’ expectations.Conclusion: SBL and PBL improve nurses’ core competence, satisfaction, and self-confidence. SBL is superior. This study promotes student-centered education, enhancing surgical nursing professionals’ quality and ensuring future patient safety.Keywords: baccalaureate nursing, education, problem-based learning, simulation training, surgical nursing
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- 2024
12. Proton spin structure and generalized polarizabilities in the strong quantum chromodynamics regime
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Ruth, D, Zielinski, R, Gu, C, Allada (Cummings), M, Badman, T, Huang, M, Liu, J, Zhu, P, Allada, K, Zhang, J, Camsonne, A, Chen, J-P, Slifer, K, Aniol, K, Annand, J, Arrington, J, Averett, T, Baghdasaryan, H, Bellini, V, Boeglin, W, Brock, J, Carlin, C, Chen, C, Cisbani, E, Crabb, D, Daniel, A, Day, D, Duve, R, Fassi, L El, Friedman, M, Fuchey, E, Gao, H, Gilman, R, Glamazdin, S, Gueye, P, Hafez, M, Han, Y, Hansen, O, Shabestari, M Hashemi, Hen, O, Higinbotham, D, Horn, T, Iqbal, S, Jensen, E, Kang, H, Keith, CD, Kelleher, A, Keller, D, Khanal, H, Korover, I, Kumbartzki, G, Li, W, Lichtenstadt, J, Lindgren, R, Long, E, Malace, S, Markowitz, P, Maxwell, J, Meekins, DM, Meziani, ZE, McLean, C, Michaels, R, Mihovilovič, M, Muangma, N, Camacho, C Munoz, Musson, J, Myers, K, Oh, Y, Carmignotto, M Pannunzio, Perdrisat, C, Phillips, S, Piasetzky, E, Pierce, J, Punjabi, V, Qiang, Y, Reimer, PE, Roblin, Y, Ron, G, Rondon, O, Russo, G, Saenboonruang, K, Sawatzky, B, Shahinyan, A, Shneor, R, Širca, S, Sjoegren, J, Solvignon-Slifer, P, Sparveris, N, Sulkosky, V, Wesselmann, F, Yan, W, Yang, H, Yao, H, Ye, Z, Yurov, M, Zhang, Y, Zhao, YX, and Zheng, X
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Mathematical Sciences ,Physical Sciences ,Fluids & Plasmas - Abstract
The strong interaction is not well understood at low energies or for interactions with low momentum transfer. Chiral perturbation theory gives testable predictions for the nucleonic generalized polarizabilities, which are fundamental quantities describing the nucleon’s response to an external field. We report a measurement of the proton’s generalized spin polarizabilities extracted with a polarized electron beam and a polarized solid ammonia target in the region where chiral perturbation theory is expected to be valid. The investigated structure function g2 characterizes the internal spin structure of the proton. From its moments, we extract the longitudinal–transverse spin polarizability δLT and twist-3 matrix element and polarizability d2¯. Our results provide discriminating power between existing chiral perturbation theory calculations and will help provide a better understanding of this strong quantum chromodynamics regime.
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- 2022
13. Synthesis, Structure, and Magnetic Property of a New Cu(II) Coordination Polymer Based on Rhombic [Cu4(μ3-OH)2]6+ Clusters
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Ju, F. Y., Kang, H. X., and Liu, G. Z.
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- 2023
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14. Development of autonomous multi-sensor ocean monitoring instrument designed for complex archipelagic waters
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Purba, N. P., Faizal, I., Valino, D. A., Kang, H. S., Sugianto, E., Martasuganda, M. K., Abimanyu, A., Bratasena, T., Zenyda, K. S., Prayogo, N., Ramdhani, F., and Khan, A. M. A.
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- 2023
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15. The Proton Spin Structure Function $g_2$ and Generalized Polarizabilities in the Strong QCD Regime
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Ruth, D., Zielinski, R., Gu, C., Allada, M., Badman, T., Huang, M., Liu, J., Zhu, P., Allada, K., Zhang, J., Camsonne, A., Chen, J. P., Slifer, K., Aniol, K., Annand, J., Arrington, J., Averett, T., Baghdasaryan, H., Bellini, V., Boeglin, W., Brock, J., Carlin, C., Chen, C., Cisbani, E., Crabb, D., Daniel, A., Day, D., Duve, R., Fassi, L. El, Friedman, M., Fuchey, E., Gao, H., Gilman, R., Glamazdin, S., Gueye, P., Hafez, M., Han, Y., Hansen, O., Shabestari, M. Hashemi, Hen, O., Higinbotham, D., Horn, T., Iqbal, S., Jensen, E., Kang, H., Keith, C. D., Kelleher, A., Keller, D., Khanal, H., Korover, I., Kumbartzki, G., Li, W., Lichtenstadt, J., Lindgren, R., Long, E., Malace, S., Markowitz, P., Maxwell, J., Meekins, D. M., Meziani, Z. E., McLean, C., Michaels, R., Mihovilovic, M., Muangma, N., Camacho, C. Munoz, Musson, J., Myers, K., Oh, Y., Carmignotto, M. Pannunzio, Perdrisat, C., Phillips, S., Piasetzky, E., Pierce, J., Punjabi, V., Qiang, Y., Reimer, P. E., Roblin, Y., Ron, G., Rondon, O., Russo, G., Saenboonruang, K., Sawatzky, B., Shahinyan, A., Shneor, R., Sjoegren, J., Solvignon-Slifer, P., Sparveris, N., Sulkosky, V., Wesselmann, F., Yan, W., Yang, H., Yao, H., Ye, Z., Yurov, M., Zhang, Y., Zhao, Y. X., and Zheng, X.
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Nuclear Experiment ,High Energy Physics - Experiment - Abstract
The strong interaction is not well understood at low energy, or for interactions with low momentum transfer $Q^2$, but one of the clearest insights we have comes from Chiral Perturbation Theory ($\chi$PT). This effective treatment gives testable predictions for the nucleonic generalized polarizabilities -- fundamental quantities describing the nucleon's response to an external field. We have measured the proton's generalized spin polarizabilities in the region where $\chi$PT is expected to be valid. Our results include the first ever data for the transverse-longitudinal spin polarizability $\delta_{LT}$, and also extend the coverage of the polarizability $\bar{d_2}$ to very low $Q^2$ for the first time. These results were extracted from moments of the structure function $g_2$, a quantity which characterizes the internal spin structure of the proton. Our experiment ran at Jefferson Lab using a polarized electron beam and a polarized solid ammonia (NH$_3$) target. The $\delta_{LT}$ polarizability has remained a challenging quantity for $\chi$PT to reproduce, despite its reduced sensitivity to higher resonance contributions; recent competing calculations still disagree with each other and also diverge from the measured neutron data at very low $Q^2$. Our proton results provide discriminating power between existing calculations, and will help provide a better understanding of this strong QCD regime.
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- 2022
16. Probing for high-momentum protons in He4 via the He4(e,e′p)X reactions
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Iqbal, S, Benmokhtar, F, Ivanov, M, See, N, Aniol, K, Higinbotham, DW, Boyd, C, Gadsby, A, Goodwill, JS, Finton, D, Boyer, A, Gilad, S, Saha, A, Udias, JM, Ye, Z, Solvignon, P, Aguilera, P, Ahmed, Z, Albataineh, H, Allada, K, Anderson, B, Anez, D, Annand, J, Arrington, J, Averett, T, Baghdasaryan, H, Bai, X, Beck, A, Beck, S, Bellini, V, Camsonne, A, Chen, C, Chen, J-P, Chirapatpimol, K, Cisbani, E, Dalton, MM, Daniel, A, Day, D, Deconinck, W, Defurne, M, Flay, D, Fomin, N, Friend, M, Frullani, S, Fuchey, E, Garibaldi, F, Gaskell, D, Gilman, R, Glamazdin, S, Gu, C, Guèye, P, Hanretty, C, Hansen, J-O, Shabestari, M Hashemi, Huang, M, Jin, G, Kalantarians, N, Kang, H, Kelleher, A, Korover, I, LeRose, J, Leckey, J, Lindgren, R, Long, E, Mammei, J, Margaziotis, DJ, Markowitz, P, Meekins, D, Meziani, Z, Michaels, R, Mihovilovic, M, Muangma, N, Camacho, C Munoz, Norum, B, Nuruzzaman, Pan, K, Phillips, S, Piasetzky, E, Pomerantz, I, Posik, M, Punjabi, V, Qian, X, Qiang, Y, Qiu, X, Reimer, PE, Rakhman, A, Riordan, S, Ron, G, Rondon-Aramayo, O, Selvy, L, Shahinyan, A, Shneor, R, Sirca, S, Slifer, K, Sparveris, N, Subedi, R, Sulkosky, V, Wang, D, Watson, JW, and Weinstein, LB
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Nuclear and Plasma Physics ,Physical Sciences ,Nuclear and plasma physics - Abstract
Experimental cross sections for the He4(e,e′p)X reactions in the missing energy range from 0.017 to 0.022 GeV and up to a missing momentum of 0.632 GeV/c at xB=1.24 and Q2=2 (GeV/c)2 are reported. The data are compared to relativistic distorted-wave impulse approximation calculations for the He4(e,e′p)H3 channel. Significantly more events are observed for pm≥0.45 GeV/c than are predicted by the theoretical model, and striking fluctuations in the ratio of data to the theoretical model around pm=0.3GeV/c are possible signals of initial-state multinucleon correlations.
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- 2022
17. Metabolic habitat imaging with hemodynamic heterogeneity predicts individual progression-free survival in high-grade glioma
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Qiao, J., Kang, H., Ran, Q., Tong, H., Ma, Q., Wang, S., Zhang, W., and Wu, H.
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- 2024
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18. Influence of Cu and Mg Content on Recrystallization Behavior in Al–Zn–Mg–Cu-Based Alloy Sheets
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Jeon, J. G., Lee, Sangjun, Choi, K. M., Kang, H., Kim, W. C., Jeon, J. H., and Bae, D. H.
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- 2023
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19. Efficacy and Safety of Microwave Ablation Assisted by Ultrasound Fusion Imaging for Primary and Secondary Liver Cancers with a Diameter of 3–7 Cm
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Yang J, Liang S, Liu H, Hu C, Guan S, Kang H, Xu E, and Yan R
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fusion imaging ,microwave ablation ,liver cancers ,ultrasound ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Jing Yang,1,* Shuang Liang,1,* Huahui Liu,1 Cai Hu,1 Sainan Guan,1 Haiyu Kang,1 Erjiao Xu,1 Ronghua Yan1,2 1Department of Medical Ultrasonics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong Province, People’s Republic of China; 2Department of Radiology, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ronghua Yan; Erjiao Xu, Department of Medical Ultrasonics, The Eighth Affiliated Hospital of Sun Yat-sen University, No. 3025 Shennan Middle Road, Futian Street, Futian District, Shenzhen City, Guangdong Province, People’s Republic of China, Tel +86 755 83982222, Fax +86 755 83980805, Email yanrh@mail3.sysu.edu.cn; xuerjiao@mail.sysu.edu.cnPurpose: To investigate the efficacy and safety of microwave ablation (MWA) assisted by ultrasound fusion imaging (FI) for primary and secondary liver cancers with a diameter of 3– 7 cm.Patients and Methods: A retrospective analysis was conducted on patients with primary and secondary liver cancers (3– 7 cm) who underwent MWA with ultrasound FI assistance in our hospital from April 2020 to May 2022. Technical success, technique efficacy, local tumor progression (LTP), major complication, intrahepatic distant recurrence (IDR), and overall survival (OS) were assessed during the follow-up period. In addition, the ablation results of tumors between the medium-sized group (3.1– 5.0 cm) and large-sized group (5.1– 7.0 cm) were compared.Results: 31 patients with 35 primary and secondary liver cancers were treated with MWA assisted by ultrasound FI. Complete ablation was achieved in 34 lesions with a technical success rate of 97.1%. Major complications occurred in 6.5% of patients (2/31), while no ablation-related deaths were reported. The median follow-up time of this study was 24 months (range:10 to 35 months). The technique efficacy rate was 97.1% (34/35), with LTP occurring in three lesions at a rate of 8.8% (3/34). The incidence of IDR was 38.7% (12/31) and the 2-year cumulative OS rate reached 96.7%. Moreover, there were no statistical differences in technique efficacy rate (p=0.286), LTP rate (p=0.328), major complication rate (p=0.503), IDR (p=0.857), and OS (p=0.118) between medium-sized group and large-sized group.Conclusion: Ultrasound FI-assisted MWA has the potential to be an effective and safe therapeutic strategy for primary and secondary liver cancers ranging from 3– 7 cm in size.Keywords: fusion imaging, microwave ablation, liver cancers, ultrasound
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- 2023
20. Characterization of ST11 and ST15 Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae from Patients with Ventilator-Associated Pneumonia
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Song S, Zhao S, Wang W, Jiang F, Sun J, Ma P, and Kang H
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klebsiella pneumoniae ,hypervirulent ,carbapenem-resistant ,ventilator-associated pneumonia ,Infectious and parasitic diseases ,RC109-216 - Abstract
Shuang Song,1,2,* Shulong Zhao,2,* Wei Wang,1 Fei Jiang,2 Jingfang Sun,2 Ping Ma,1,2 Haiquan Kang2 1Medical Technology School, Xuzhou Medical University, Xuzhou, People’s Republic of China; 2Department of Clinical Laboratory, Affiliated Hospital of Xuzhou Medical University, Xuzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Haiquan Kang, Department of Laboratory Medicine, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221000, People’s Republic of China, Tel +86-516 85802759, Email hqk811029@163.com Ping Ma, Medical Technology School, Xuzhou Medical University, Department of Laboratory Medicine, Xuzhou, People’s Republic of China, Tel +86-516 85807017, Email pingm62@aliyun.comBackground: The prevalence of carbapenem-resistant hypervirulent Klebsiella pneumoniae (hv-CRKP) is a serious public threat globally. Here, we performed clinical, molecular, and phenotypic monitoring of hv-CRKP strains isolated from the intensive care unit (ICU) to offer evidence for prevention and control in hospitals.Methods: Data analysis of ICU patients suffering from ventilator-associated pneumonia (VAP) because of hv-CRKP infection, admitted at the Chinese Teaching Hospital between March 2019 and September 2021 was performed. Patients’ antibiotic-resistance genes, virulence-associated genes, and capsular serotypes of these isolates were detected. Homology analysis of the strains was performed by MLST and PFGE. Six different strains were tested for their virulence traits using the serum killing test and the Galleria mellonella infection assay. For whole genome sequencing, KP3 was selected as a representative strain.Results: Clinical data of 19 hv-CRKP-VAP patients were collected and their hv-CRKP were isolated, including 10 of ST11-KL64, 4 of ST15-KL112, 2 of ST11-KL47, 1 of ST15-KL19, 1 of ST17-KL140, and 1 of ST48-KL62. Four ST15 and 8 ST11 isolates revealed high homology, respectively. Most strains carried the carbapenemase gene blaKPC-2 (14/19, 73.68%), followed by blaOXA-232 (4/19, 21.05%). All strains were resistant to almost all the antibiotics except polymyxin and tigacycline. Ten patients were treated with polymyxin or tigacycline based on their susceptibility results, and unfortunately 6 patients died. All strains exhibited a hyper-viscous phenotype, and the majority (17/19, 89.47%) of them contained rmpA and rmpA2. The serum killing test showed that KP9 was resistant to normal healthy serum, others were intermediately or highly sensitive. G. mellonella larvae infection assay suggested that the strains in this study were hypervirulent.Conclusion: This study highlights the dominant strain and molecular epidemiology of hv-CRKP in a hospital in China. We should pay more attention to the effect of hv-CRKP on VAP, strengthen monitoring and control transmission.Keywords: Klebsiella pneumoniae, hypervirulent, carbapenem-resistant, ventilator-associated pneumonia
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- 2023
21. PMU Simulation and Application for Power System Stability Monitoring
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Kang, H., Cvorovic, B., Mycock, C., and Mai, R.
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- 2010
22. Measurement of the Bjorken Sum at very low $Q^2$
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Deur, A., Chen, J. P., Kuhn, S. E., Peng, C., Ripani, M., Sulkosky, V., Adhikari, K., Battaglieri, M., Burkert, V. D., Cates, G. D., De Vita, R., Dodge, G. E., Fassi, L. El, Garibaldi, F., Kang, H., Osipenko, M., Singh, J. T., Slifer, K., Zhang, J., and Zheng, Xiaochao
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Nuclear Experiment - Abstract
We present new data on the Bjorken sum $\overline \Gamma_1^{p-n}(Q^2)$ at 4-momentum transfer $ 0.021 \leq Q^2 \leq 0.496$ GeV$^2$. The data were obtained in two experiments performed at Jefferson Lab: EG4 on polarized protons and deuterons, and E97110 on polarized $^3$He from which neutron data were extracted. The data cover the domain where chiral effective field theory ($\chi$EFT), the leading effective theory of the Strong Force at large distances, is expected to be applicable. We find that our data and the predictions from $\chi$EFT are only in marginal agreement. This is somewhat surprising as the contribution from the $\Delta(1232)$ resonance is suppressed in this observable, which should make it more reliably predicted by $\chi$EFT than quantities in which the $\Delta$ contribution is important. The data are also compared to a number of phenomenological models with various degrees of agreement., Comment: 6 pages, 1 figure. Final version published in Phys. Lett. B
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- 2021
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23. Patient-reported outcomes with selpercatinib treatment in patients with RET-driven cancers in the phase I/II LIBRETTO-001 trial
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Raez, L.E., Kang, H., Ohe, Y., Khanal, M., Han, Y., Szymczak, S., Barker, S.S., and Gilligan, A.M.
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- 2024
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24. Resource Allocation Efficiency of Urban Medical and Health Financial Expenditure Under the Background of Employees’ Health
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Gong C and Kang H
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data envelopment analysis ,difference-in-differences ,regression model ,employees' health ,resource allocation efficiency ,Public aspects of medicine ,RA1-1270 - Abstract
Chunbo Gong, Huaixing Kang ShanDong University of Traditional Chinese Medicine, JiNan, 250355, People’s Republic of ChinaCorrespondence: Huaixing Kang, Email Huaixingkang@outlook.comIntroduction: The study proposes a method based on difference-in-differences (DID) to improve the resource allocation efficiency of medical and health financial expenditure to better guarantee the health level of enterprise employees. The DEA method is utilized to measure the comprehensive technology, pure technology, and scale as the resource allocation efficiency values of urban medical and health financial expenditure.Methods: The proposed method includes the use of DEA to measure the resource allocation efficiency values of urban medical and health financial expenditure. The benchmark regression model and DID model are used to analyze the impact effect, robustness, and parallel trend of the policy.Results: The study shows that the proposed method effectively evaluates and analyzes the impact of medical comprehensive reform on the resource allocation efficiency of urban medical and health financial expenditure. The comprehensive medical reform can improve the comprehensive efficiency and scale efficiency of urban medical and health financial expenditure, leading to improved resource allocation efficiency of urban employees’ medical and health financial expenditure. The results also indicate a significant positive effect on the time trend, which can have a long-term impact and effectiveness.Discussion: The proposed method can provide useful insights into the resource allocation efficiency of medical and health financial expenditure, which can help improve the health level of enterprise employees. The study suggests that comprehensive medical reform can be an effective way to improve resource allocation efficiency and guarantee the health of employees in urban areas. Further research can be conducted to evaluate the impact of medical reform on other aspects of health care, such as quality and accessibility.Keywords: data envelopment analysis, difference-in-differences, regression model, employees’ health, resource allocation efficiency
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- 2023
25. Multimodel habitats constructed by perfusion and/or diffusion MRI predict isocitrate dehydrogenase mutation status and prognosis in high-grade gliomas
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Liu, J., Cong, C., Zhang, J., Qiao, J., Guo, H., Wu, H., Sang, Z., Kang, H., Fang, J., and Zhang, W.
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- 2024
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26. High-order phase-dependent asymmetry in the above-threshold ionization plateau
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Kübel, M., Wustelt, P., Zhang, Y., Skruszewicz, S., Hoff, D., Würzler, D., Kang, H., Zille, D., Adolph, D., Sayler, A. M., Paulus, G. G., Dumergue, M., Nayak, A., Flender, R., Haizer, L., Kurucz, M., Kiss, B., Kühn, S., Fetić, B., and Milošević, D. B.
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Physics - Atomic Physics ,Physics - Optics - Abstract
Above-threshold ionization spectra from cesium are measured as a function of the carrier-envelope phase (CEP) using laser pulses centered at 3.1 $\mu$m wavelength. The directional asymmetry in the energy spectra of backscattered electrons oscillates three times, rather than once, as the CEP is changed from $0$ to $2\pi$. Using the improved strong-field approximation, we show that the unusual behavior arises from the interference of few quantum orbits. We discuss the conditions for observing the high-order CEP dependence, and draw an analogy with time-domain holography with electron wave packets.
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- 2021
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27. Measurement of the proton spin structure at long distances
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Zheng, X., Deur, A., Kang, H., Kuhn, S. E., Ripani, M., Zhang, J., Adhikari, K. P., Adhikari, S., Amaryan, M. J., Atac, H., Avakian, H., Barion, L., Battaglieri, M., Bedlinskiy, I., Benmokhtar, F., Bianconi, A., Biselli, A. S., Boiarinov, S., Bondi, M., Bossu, F., Bosted, P., Briscoe, W. J., Brock, J., Brooks, W. K., Bulumulla, D., Burkert, V. D., Carlin, C., Carman, D. S., Carvajal, J. C., Celentano, A., Chatagnon, P., Chetry, T., Chen, J. -P., Choi, S., Ciullo, G., Clark, L., Cole, P. L., Contalbrigo, M., Crede, V., D'Angelo, A., Dashyan, N., De Vita, R., Defurne, M., Diehl, S., Djalali, C., Drozdov, V. A., Dupre, R., Ehrhart, M., Alaoui, A. El, Elouadrhiri, L., Eugenio, P., Fedotov, G., Fegan, S., Fersch, R., Filippi, A., Forest, T. A., Ghandilyan, Y., Gilfoyle, G. P., Giovanetti, K. L., Girod, F. -X., Glazier, D. I., Gothe, R. W., Griffioen, K. A., Guidal, M., Guler, N., Guo, L., Hafidi, K., Hakobyan, H., Hattawy, M., Hayward, T. B., Heddle, D., Hicks, K., Hobart, A., Holmstrom, T., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jo, H. S., Joo, K., Joosten, S., Keith, C. D., Keller, D., Khanal, A., Khandaker, M., Kim, C. W., Kim, W., Klein, F. J., Kripko, A., Kubarovsky, V., Lanza, L., Leali, M., Lenisa, P., livingston, K., Long, E., MacGregor, I. J. D., Markov, N., Marsicano, L., Mascagna, V., McKinnon, B., Meekins, D. G., Mineeva, T., Mirazita, M., Mokeev, V., Mullen, C., Nadel-Turonski, P., Neupane, K., Niccolai, S., Osipenko, M., Ostrovidov, A. I., Paolone, M., Pappalardo, L., Park, K., Pasyuk, E., Phelps, W., Phillips, S. K., Pogorelko, O., Poudel, J., Prok, Y., Raue, B. A., Ritman, J., Rizzo, A., Rosner, G., Rossi, P., Rowley, J., Sabatie, F., Salgado, C., Schmidt, A., Schumacher, R. A., Seely, M. L., Sharabian, Y. G., Shrestha, U., Sirca, S., Slifer, K., Sparveris, N., Stepanyan, S., Strakovsky, I. I., Strauch, S., Sulkosky, V., Tyler, N., Ungaro, M., Venturelli, L., Voskanyan, H., Voutier, E., Watts, D. P., Wei, X., Weinstein, L. B., Wood, M. H., Yale, B., Zachariou, N., and Zhao, Z. W.
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Nuclear Experiment ,High Energy Physics - Experiment - Abstract
Measuring the spin structure of protons and neutrons tests our understanding of how they arise from quarks and gluons, the fundamental building blocks of nuclear matter. At long distances the coupling constant of the strong interaction becomes large, requiring non-perturbative methods to calculate quantum chromodynamics processes, such as lattice gauge theory or effective field theories. Here we report proton spin structure measurements from scattering a polarized electron beam off polarized protons. The spin-dependent cross-sections were measured at large distances, corresponding to the region of low momentum transfer squared between 0.012 and 1.0 GeV$^2$. This kinematic range provides unique tests of chiral effective field theory predictions. Our results show that a complete description of the nucleon spin remains elusive, and call for further theoretical works, e.g. in lattice quantum chromodynamics. Finally, our data extrapolated to the photon point agree with the Gerasimov-Drell-Hearn sum rule, a fundamental prediction of quantum field theory that relates the anomalous magnetic moment of the proton to its integrated spin-dependent cross-sections., Comment: Published version. 10 pages, 5 figures. 20 pages of supplementary material (data tables and a figure)
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- 2021
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28. Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease
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Rogers, Maximillian A., Bartoli-Leonard, Francesca, Zheng, Kang H., Small, Aeron M., Chen, Hao Yu, Clift, Cassandra L., Asano, Takaharu, Kuraoka, Shiori, Blaser, Mark C., Perez, Katelyn A., Natarajan, Pradeep, Yeang, Calvin, Stroes, Erik S.G., Tsimikas, Sotirios, Engert, James C., Thanassoulis, George, O’Donnell, Christopher J., Aikawa, Masanori, Singh, Sasha A., and Aikawa, Elena
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- 2024
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29. Metal plasmon-enhanced lanthanide fluorescent nanoparticles for monitoring aqueous copper ions
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Nguyen, M.-C.T., Nguyen, H.-Q., Kang, H., Goddati, M., Lee, S.-Y., Yee, K.-J., and Lee, J.
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- 2023
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30. Reaching thermal noise at ultra-low radio frequencies: the Toothbrush radio relic downstream of the shock front
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de Gasperin, F., Brunetti, G., Bruggen, M., van Weeren, R., Williams, W. L., Botteon, A., Cuciti, V., Dijkema, T. J., Edler, H., Iacobelli, M., Kang, H., Offringa, A., Orru, E., Pizzo, R., Rafferty, D., Rottgering, H., and Shimwell, T.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Ultra-low frequency observations (<100 MHz) are particularly challenging because they are usually performed in a low signal-to-noise ratio regime due to the high sky temperature and because of ionospheric disturbances whose effects are inversely proportional to the observing frequency. Nonetheless, these observations are crucial to study the emission from low-energy populations of cosmic rays. We aim to obtain the first thermal-noise limited (~ 1.5 mJy/beam) deep continuum radio map using the LOFAR Low Band Antenna (LBA) system. Our demonstration observation targeted the galaxy cluster RX J0603.3+4214 (the "Toothbrush" cluster). We used the resulting ultra-low frequency (58 MHz) image to study cosmic-ray acceleration and evolution in the post shock region, as well as their relation with the presence of a radio halo. We describe the data reduction we have used to calibrate LOFAR LBA observations. The resulting image is combined with observations at higher frequencies (LOFAR 150 MHz and VLA 1500 MHz) to extract spectral information. We obtained the first thermal-noise limited image from an observation carried out with the LOFAR LBA system using all Dutch stations at a central frequency of 58 MHz. With 8 hours of data, we reached an rms noise of 1.3 mJy/beam at a resolution of 18" x 11". The procedure we have developed is an important step forward towards routine high-fidelity imaging with the LOFAR LBA. The analysis of the radio spectra shows that the radio relic extends to distances of 800 kpc downstream from the shock front, larger than what allowed by electron cooling time. Furthermore, the shock wave started accelerating electrons already at a projected distance of <300 kpc from the crossing point of the two clusters. These results can be explained if electrons are reaccelerated downstream by background turbulence possibly combined with projection effects., Comment: 15 pages, 19 figures, accepted A&A
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- 2020
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31. Novel observation of isospin structure of short-range correlations in calcium isotopes
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Nguyen, D., Ye, Z., Aguilera, P., Ahmed, Z., Albataineh, H., Allada, K., Anderson, B., Anez, D., Aniol, K., Annand, J., Arrington, J., Averett, T., Baghdasaryan, H., Bai, X., Beck, A., Beck, S., Bellini, V., Benmokhtar, F., Camsonne, A., Chen, C., Chen, J. -P., Chirapatpimol, K., Cisbani, E., Dalton, M. M., Daniel, A., Day, D., Deconinck, W., Defurne, M., Flay, D., Fomin, N., Friend, M., Frullani, S., Fuchey, E., Garibaldi, F., Gaskell, D., Gilad, S., Gilman, R., Glamazdin, S., Gu, C., Guèye, P., Hanretty, C., Hansen, J. -O., Shabestari, M. Hashemi, Higinbotham, D. W., Huang, M., Iqbal, S., Jin, G., Kalantarians, N., Kang, H., her, A. Kelle, Korover, I., LeRose, J., Leckey, J., Li, S., Lindgren, R., Long, E., Mammei, J., Margaziotis, D. J., Markowitz, P., Meekins, D., Meziani, Z. -E., Michaels, R., Mihovilovi\v, M., Muangma, N., Camacho, C. Munoz, Norum, B. E., Nuruzzaman, Pan, K., Phillips, S., Piasetzky, E., Pomerantz, I., Posik, M., Punjabi, V., Qian, X., Qiang, Y., Qiu, X., Reimer, P. E., Rakhman, A., Riordan, S., Ron, G., Rondon-Aramayo, O., Saha, A., Selvy, L., Shahinyan, A., Shneor, R., \v, S., Slifer, K., Solvignon, P., Sparveris, N., Subedi, R., Sulkosky, V., Wang, D., Watson, J. W., Weinstein, L. B., Wojtsekhowski, B., Wood, S. A., Yaron, I., Zhan, X., Zhang, J., Zhang, Y. W., Zhao, B., Zheng, X., Zhu, P., and Zielinski, R.
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Nuclear Experiment - Abstract
Short Range Correlations (SRCs) have been identified as being responsible for the high momentum tail of the nucleon momentum distribution, n(k). Hard, short-range interactions of nucleon pairs generate the high momentum tail and imprint a universal character on n(k) for all nuclei at large momentum. Triple coincidence experiments have shown a strong dominance of np pairs, but these measurements involve large final state interactions. This paper presents the results from Jefferson Lab experiment E08014 which measured inclusive electron scattering cross-section from Ca isotopes. By comparing the inclusive cross section from 48Ca to 40Ca in a kinematic region dominated by SRCs we provide a new way to study the isospin structure of SRCs., Comment: 7 pages, 3 figures
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- 2020
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32. Initial results from the New Horizons exploration of 2014 MU69, a small Kuiper Belt Object
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Stern, S. A., Weaver, H. A., Spencer, J. R., Olkin, C. B., Gladstone, G. R., Grundy, W. M., Moore, J. M., Cruikshank, D. P., Elliott, H. A., McKinnon, W. B., Parker, J. Wm., Verbiscer, A. J., Young, L. A., Aguilar, D. A., Albers, J. M., Andert, T., Andrews, J. P., Bagenal, F., Banks, M. E., Bauer, B. A., Bauman, J. A., Bechtold, K. E., Beddingfield, C. B., Behrooz, N., Beisser, K. B., Benecchi, S. D., Bernardoni, E., Beyer, R. A., Bhaskaran, S., Bierson, C. J., Binzel, R. P., Birath, E. M., Bird, M. K., Boone, D. R., Bowman, A. F., Bray, V. J., Britt, D. T., Brown, L. E., Buckley, M. R., Buie, M. W., Buratti, B. J., Burke, L. M., Bushman, S. S., Carcich, B., Chaikin, A. L., Chavez, C. L., Cheng, A. F., Colwell, E. J., Conard, S. J., Conner, M. P., Conrad, C. A., Cook, J. C., Cooper, S. B., Custodio, O. S., Ore, C. M. Dalle, Deboy, C. C., Dharmavaram, P., Dhingra, R. D., Dunn, G. F., Earle, A. M., Egan, A. F., Eisig, J., El-Maarry, M. R., Engelbrecht, C., Enke, B. L., Ercol, C. J., Fattig, E. D., Ferrell, C. L., Finley, T. J., Firer, J., Fischetti, J., Folkner, W. M., Fosbury, M. N., Fountain, G. H., Freeze, J. M., Gabasova, L., Glaze, L. S., Green, J. L., Griffith, G. A., Guo, Y., Hahn, M., Hals, D. W., Hamilton, D. P., Hamilton, S. A., Hanley, J. J., Harch, A., Harmon, K. A., Hart, H. M., Hayes, J., Hersman, C. B., Hill, M. E., Hill, T. A., Hofgartner, J. D., Holdridge, M. E., Horányi, M., Hosadurga, A., Howard, A. D., Howett, C. J. A., Jaskulek, S. E., Jennings, D. E., Jensen, J. R., Jones, M. R., Kang, H. K., Katz, D. J., Kaufmann, D. E., Kavelaars, J. J., Keane, J. T., Keleher, G. P., Kinczyk, M., Kochte, M. C., Kollmann, P., Krimigis, S. M., Kruizinga, G. L., Kusnierkiewicz, D. Y., Lahr, M. S., Lauer, T. R., Lawrence, G. B., Lee, J. E., Lessac-Chenen, E. J., Linscott, I. R., Lisse, C. M., Lunsford, A. W., Mages, D. M., Mallder, V. A., Martin, N. P., May, B. H., McComas, D. J., McNutt, R. L., Mehoke, Jr. D. S., Mehoke, T. S., Nelson, D. S., Nguyen, H. D., Núñez, J. I., Ocampo, A. C., Owen, W. M., Oxton, G. K., Parker, A. H., Pätzold, M., Pelgrift, J. Y., Pelletier, F. J., Pineau, J. P., Piquette, M. R., Porter, S. B., Protopapa, S., Quirico, E., Redfern, J. A., Regiec, A. L., Reitsema, H. J., Reuter, D. C., Richardson, D. C., Riedel, J. E., Ritterbush, M. A., Robbins, S. J., Rodgers, D. J., Rogers, G. D., Rose, D. M., Rosendall, P. E., Runyon, K. D., Ryschkewitsch, M. G., Saina, M. M., Salinas, M. J., Schenk, P. M., Scherrer, J. R., Schlei, W. R., Schmitt, B., Schultz, D. J., Schurr, D. C., Scipioni, F., Sepan, R. L., Shelton, R. G., Showalter, M. R., Simon, M., Singer, K. N., Stahlheber, E. W., Stanbridge, D. R., Stansberry, J. A., Steffl, A. J., Strobel, D. F., Stothoff, M. M., Stryk, T., Stuart, J. R., Summers, M. E., Tapley, M. B., Taylor, A., Taylor, H. W., Tedford, R. M., Throop, H. B., Turner, L. S., Umurhan, O. M., Van Eck, J., Velez, D., Versteeg, M. H., Vincent, M. A., Webbert, R. W., Weidner, S. E., Weigle II, G. E., Wendel, J. R., White, O. L., Whittenburg, K. E., Williams, B. G., Williams, K. E., Williams, S. P., Winters, H. L., Zangari, A. M., and Zurbuchen, T. H.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The Kuiper Belt is a distant region of the Solar System. On 1 January 2019, the New Horizons spacecraft flew close to (486958) 2014 MU69, a Cold Classical Kuiper Belt Object, a class of objects that have never been heated by the Sun and are therefore well preserved since their formation. Here we describe initial results from these encounter observations. MU69 is a bi-lobed contact binary with a flattened shape, discrete geological units, and noticeable albedo heterogeneity. However, there is little surface color and compositional heterogeneity. No evidence for satellites, ring or dust structures, gas coma, or solar wind interactions was detected. By origin MU69 appears consistent with pebble cloud collapse followed by a low velocity merger of its two lobes., Comment: 43 pages, 8 figure
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- 2020
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33. Melting point depression and phase identification of sugar alcohols encapsulated in zif nanopores
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Dames, C, Urban, JJ, and Kang, H
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Physical Chemistry ,Chemical Sciences ,Engineering ,Technology - Abstract
Sugar alcohols (SAs) have attractive characteristics as phase-change materials, but their relatively high melting temperature limits their application in the real world. Nanoconfinement can be a useful parameter to reduce the melting temperature to pragmatic ranges. Using molecular dynamics simulations, we investigate the phases and behaviors of encapsulated SA in ZIF-8 and ZIF-11, which cannot be experimentally observed. Based on reliable partial charges for the zeolitic imidazolate framework (ZIF) structures calculated by a density functional theory, structural analysis shows that the SA's attractive interaction with the ZIF structure frustrates the SA crystallization and also elucidates the second-order phase transition between amorphous phases. A methodology is suggested to determine the phase transition temperature of confined materials and used to quantify the melting temperature depression of the ZIF-confined SAs. We also explored the thermal conductivity of SA-in-ZIF composites. Phonon frequency analysis verifies that the presence of SA molecules enhances the heat transfer by adding heat pathways between the nanoporous structure of ZIFs.
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- 2021
34. Auditory cortex hyperconnectivity before rTMS is correlated with tinnitus improvement
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Kim, E., Kang, H., Noh, T.-S., Oh, S.-H., and Suh, M.-W.
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- 2023
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35. Overexpression of acdS in petunia reduces ethylene production and improves tolerance to heat stress
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Baek, S., primary, Naing, A. H., additional, Kang, H., additional, Chung, M. Y., additional, and Kim, C. K., additional
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- 2024
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36. Novel observation of isospin structure of short-range correlations in calcium isotopes
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Nguyen, D, Ye, Z, Aguilera, P, Ahmed, Z, Albataineh, H, Allada, K, Anderson, B, Anez, D, Aniol, K, Annand, J, Arrington, J, Averett, T, Baghdasaryan, H, Bai, X, Beck, A, Beck, S, Bellini, V, Benmokhtar, F, Camsonne, A, Chen, C, Chen, JP, Chirapatpimol, K, Cisbani, E, Dalton, MM, Daniel, A, Day, D, Deconinck, W, Defurne, M, Flay, D, Fomin, N, Friend, M, Frullani, S, Fuchey, E, Garibaldi, F, Gaskell, D, Gilad, S, Gilman, R, Glamazdin, S, Gu, C, Guèye, P, Hanretty, C, Hansen, JO, Shabestari, MH, Higinbotham, DW, Huang, M, Iqbal, S, Jin, G, Kalantarians, N, Kang, H, Kelleher, A, Korover, I, Lerose, J, Leckey, J, Li, S, Lindgren, R, Long, E, Mammei, J, Margaziotis, DJ, Markowitz, P, Meekins, D, Meziani, ZE, Michaels, R, Mihovilovic, M, Muangma, N, Camacho, CM, Norum, BE, Nuruzzaman, Pan, K, Phillips, S, Piasetzky, E, Pomerantz, I, Posik, M, Punjabi, V, Qian, X, Qiang, Y, Qiu, X, Reimer, PE, Rakhman, A, Riordan, S, Ron, G, Rondon-Aramayo, O, Saha, A, Selvy, L, Shahinyan, A, Shneor, R, Širca, S, Slifer, K, Solvignon, P, Sparveris, N, Subedi, R, Sulkosky, V, Wang, D, Watson, JW, Weinstein, LB, Wojtsekhowski, B, Wood, SA, Yaron, I, Zhan, X, Zhang, J, and Zhang, YW
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nucl-ex - Abstract
Short-range correlations (SRCs) have been identified as being responsible for the high-momentum tail of the nucleon momentum distribution, n(k). Hard, short-range interactions of nucleon pairs generate the high-momentum tail and imprint a universal character on n(k) for all nuclei at large momentum. Triple coincidence experiments have shown a strong dominance of np pairs, but these measurements involve large final-state interactions. This paper presents the results from Jefferson Lab experiment E08014 which measured inclusive electron scattering cross section from Ca isotopes. By comparing the inclusive cross section from Ca48 to Ca40 in a kinematic region dominated by SRCs we provide a new way to study the isospin structure of SRCs.
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- 2020
37. Stereotactic Body Radiation Therapy for Pulmonary Metastasis from Colorectal Adenocarcinoma: Biologically Effective Dose 150 Gy is Preferred for Tumour Control
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Lee, T.H., Kang, H.-C., Chie, E.K., Kim, H.J., Wu, H.-G., Lee, J.H., and Kim, K.S.
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- 2023
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38. XtalCAMP: A comprehensive program for the analysis and visualization of scanning Laue X-ray micro-/nanodiffraction data
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Li, Y, Chen, K, Dang, X, Zhang, F, Tamura, N, Ku, CS, Kang, H, and Wenk, HR
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scanning Laue X-ray micro-/nanodiffraction ,computer programs ,crystal orientation maps ,strain/stress analysis ,texture analysis ,Mathematical Sciences ,Physical Sciences ,Engineering ,Inorganic & Nuclear Chemistry - Abstract
© 2020. XtalCAMP is a software package based on the MATLAB platform, which is suitable for, but not limited to, the analysis and visualization of scanning Laue X-ray micro-/nanodiffraction data. The main objective of the software is to provide complementary functionalities to the Laue indexing software packages used at several synchrotron beamlines. The graphical user interfaces allow the easy analysis of characteristic microstructure features, including real-time intensity mapping for a quick examination of phase, grain and defect distribution, 2D color-coded mapping of microstructural properties from the output of other Laue indexing software, crystal orientation visualization, grain boundary characterization based on orientation/misorientation calculation, principal strain/stress analysis, and strain ellipsoid representation, as well as a series of additional toolkits. As an example, XtalCAMP is applied to the microstructural investigation of a solution-heat-treated Ni-based superalloy manufactured using a laser 3D-printing technique, and a deformed natural quartzite from Val Bregaglia in the Central Alps.
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- 2020
39. Analysis of GaInN light-emitting diodes with rods and lenses fabricated by direct optical wiring technology
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Kang, H., Kim, C. C., and Cho, J.
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- 2022
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40. Proton Form Factor Ratio, $\mu_p G_E^p/G_M^p$ from Double Spin Asymmetry
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Liyanage, A., Armstrong, W., Kang, H., Maxwell, J., Mulholland, J., Ndukum, L., Ahmidouch, A., Albayrak, I., Asaturyan, A., Ates, O., Baghdasaryan, H., Boeglin, W., Bosted, P., Brash, E., Butuceanu, C., Bychkov, M., Carter, P., Chen, C., Chen, J-P., Choi, S., Christy, E., Covrig, S., Crabb, D., Danagoulian, S., Daniel, A., Davidenko, A. M., Davis, B., Day, D., Deconinck, W., Deur, A., Dunne, J., Dutta, D., Fassi, L. El, Elaasar, M., Ellis, C., Ent, R., Flay, D., Frlez, E., Gaskell, D., Geagla, O., German, J., Gilman, R., Gogami, T., Gomez, J., Goncharenko, Y. M., Hashimoto, O., Higinbotham, D., Horn, T., Huber, G. M., Jones, M., Jones, M. K., Kalantarians, N., Kang, H-K., Kawama, D., Keppel, C., Khandaker, M., Kim, Y., King, P. M., Kohl, M., Kovacs, K., Kubarovsky, V., Li, Y., Liyanage, N., Mamyan, V., Markowitz, P., Maruta, T., Melnik, Y. M., Meziani, Z-E., Mkrtchyan, A., Mkrtchyan, H., Mochalov, V. V., Monaghan, P., Narayan, A., Nakamura, S. N., Nuruzzaman, Pentchev, L., Pocanic, D., Posik, M., Puckett, A., Qiu, X., Reinhold, J., Riordan, S., Roche, J., Rondo'n, O. A., Sawatzky, B., Shabestari, M., Slifer, K., Smith, G., Soloviev, L. F., Solvignon, P., Tadevosyan, V., Tang, L., Vasiliev, A. N., Veilleux, M., Walton, T., Wesselmann, F., Wood, S. A., Yao, H., Ye, Z., and Zhu, L.
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Nuclear Experiment - Abstract
The ratio of the electric and magnetic form factor of the proton, $\mu_p G_E^p/G_M^p$, has been measured for elastic electron-proton scattering with polarized beam and target up to four-momentum transfer squared, $Q^2=5.66$ (GeV/c)$^2$ using the double spin asymmetry for target spin orientation aligned nearly perpendicular to the beam momentum direction. This measurement of $\mu_p G_E^p/G_M^p$ agrees with the $Q^2$ dependence of previous recoil polarization data and reconfirms the discrepancy at high $Q^2$ between the Rosenbluth and the polarization-transfer method with a different measurement technique and systematic uncertainties uncorrelated to those of the recoil-polarization measurements. The form factor ratio at $Q^2$=2.06 (GeV/c)$^2$ has been measured as $\mu_p G_E^p/G_M^p = 0.720 \pm 0.176_{stat} \pm 0.039_{sys}$, which is in agreement with an earlier measurement with the polarized target technique at similar kinematics. The form factor ratio at $Q^2$=5.66 (GeV/c)$^2$ has been determined as $\mu_p G_E^p/G_M^p=0.244\pm0.353_{stat}\pm0.013_{sys}$, which represents the highest $Q^2$ reach with the double spin asymmetry with polarized target to date.
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- 2018
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41. Revealing Color Forces with Transverse Polarized Electron Scattering
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Armstrong, W., Kang, H., Liyanage, A., Maxwell, J., Mulholland, J., Ndukum, L., Ahmidouch, A., Albayrak, I., Asaturyan, A., Ates, O., Baghdasaryan, H., Boeglin, W., Bosted, P., Brash, E., Butuceanu, C., Bychkov, M., Carter, P., Chen, C., Chen, J. -P., Choi, S., Christy, M. E., Covrig, S., Crabb, D., Danagoulian, S., Daniel, A., Davidenko, A. M., Davis, B., Day, D., Deconinck, W., Deur, A., Dunne, J., Dutta, D., Fassi, L. El, Ellis, C., Ent, R., Flay, D., Frlez, E., Gaskell, D., Geagla, O., German, J., Gilman, R., Gogami, T., Gomez, J., Goncharenko, Y. M., Hashimoto, O., Higinbotham, D., Horn, T., Huber, G. M., Jones, M., Jones, M. K., Kalantarians, N., Kang, H-K., Kawama, D., Keith, C., Keppel, C., Khandaker, M., Kim, Y., King, P. M., Kohl, M., Kovacs, K., Kubarovsky, V., Li, Y., Liyanage, N., Luo, W., Mack, D., Mamyan, V., Markowitz, P., Maruta, T., Meekins, D., Melnik, Y. M., Meziani, Z. -E., Mkrtchyan, A., Mkrtchyan, H., Mochalov, V. V., Monaghan, P., Narayan, A., Nakamura, S. N., Nuruzzaman, A., Pentchev, L., Pocanic, D., Posik, M., Puckett, A., Qiu, X., Reinhold, J., Riordan, S., Roche, J., Rondón, O. A., Sawatzky, B., Shabestari, M., Slifer, K., Smith, G., Soloviev, L. F., Solvignon, P., Tadevosyan, V., Tang, L., Vasiliev, A. N., Veilleux, M., Walton, T., Wesselmann, F., Wood, S., Yao, H., Ye, Z., Zhang, J., and Zhu, L.
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Nuclear Experiment - Abstract
The Spin Asymmetries of the Nucleon Experiment (SANE) measured two double spin asymmetries using a polarized proton target and polarized electron beam at two beam energies, 4.7 GeV and 5.9 GeV. A large-acceptance open-configuration detector package identified scattered electrons at 40$^{\circ}$ and covered a wide range in Bjorken $x$ ($0.3 < x < 0.8$). Proportional to an average color Lorentz force, the twist-3 matrix element, $\tilde{d}_2^p$, was extracted from the measured asymmetries at $Q^2$ values ranging from 2.0 to 6.0 GeV$^2$. The data display the opposite sign compared to most quark models, including the lattice QCD result, and an apparently unexpected scale dependence. Furthermore when combined with the neutron data in the same $Q^2$ range the results suggest a flavor independent average color Lorentz force.
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- 2018
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42. Design and Performance of the Spin Asymmetries of the Nucleon Experiment
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Maxwell, J. D., Armstrong, W. R., Choi, S., Jones, M. K., Kang, H., Liyanage, A., Meziani, Z. -E., Mulholland, J., Ndukum, L., Rondon, O. A., Ahmidouch, A., Albayrak, I., Asaturyan, A., Ates, O., Baghdasaryan, H., Boeglin, W., Bosted, P., Brash, E., Brock, J., Butuceanu, C., Bychkov, M., Carlin, C., Carter, P., Chen, C., Chen, J. -P., Christy, M. E., Covrig, S., Crabb, D., Danagoulian, S., Daniel, A., Davidenko, A. M., Davis, B., Day, D., Deconinck, W., Deur, A., Dunne, J., Dutta, D., Fassi, L. El, Elaasar, M., Ellis, C., Ent, R., Flay, D., Frlez, E., Gaskell, D., Geagla, O., German, J., Gilman, R., Gogami, T., Gomez, J., Goncharenko, Y. M., Hashimoto, O., Higinbotham, D. W., Horn, T., Huber, G. M., Jones, M., Kalantarians, N., Kang, H. K., Kawama, D., Keith, C., Keppel, C., Khandaker, M., Kim, Y., King, P. M., Kohl, M., Kovacs, K., Kubarovsky, V., Li, Y., Liyanage, N., Luo, W., Mamyan, V., Markowitz, P., Maruta, T., Meekins, D., Melnik, Y. M., Mkrtchyan, A., Mkrtchyan, H., Mochalov, V. V., Monaghan, P., Narayan, A., Nakamura, S. N., Nuruzzaman, Pentchev, L., Pocanic, D., Posik, M., Puckett, A., Qiu, X., Reinhold, J., Riordan, S., Roche, J., Sawatzky, B., Shabestari, M., Slifer, K., Smith, G., Soloviev, L., Solvignon, P., Tadevosyan, V., Tang, L., Vasiliev, A. N., Veilleux, M., Walton, T., Wesselmann, F., Wood, S. A., Yao, H., Ye, Z., and Zhu, L.
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Physics - Instrumentation and Detectors ,Nuclear Experiment - Abstract
The Spin Asymmetries of the Nucleon Experiment (SANE) performed inclusive, double-polarized electron scattering measurements of the proton at the Continuous Electron Beam Accelerator Facility at Jefferson Lab. A novel detector array observed scattered electrons of four-momentum transfer $2.5 < Q^2< 6.5$ GeV$^2$ and Bjorken scaling $0.3
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- 2017
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43. Measurement of the single-spin asymmetry $A_y^0$ in quasi-elastic $^3$He$^\uparrow$($e,e'n$) scattering at $0.4 < Q^2 < 1.0$ GeV$/c^2$
- Author
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Long, E., Zhang, Y. W., Mihoviloviv, M., Jin, G., Sulkosky, V., Kelleher, A., Anderson, B., Higinbotham, D. W., Sirca, S., Allada, K., Annand, J. R. M., Averett, T., Bertozzi, W., Boeglin, W., Bradshaw, P., Camsonne, A., Canan, M., Cates, G. D., Chen, C., Chen, J. -P., Chudakov, E., De Leo, R., Deng, X., Deur, A., Dutta, C., Fassi, L. El, Flay, D., Frullani, S., Garibaldi, F., Gao, H., Gilad, S., Gilman, R., Glamazdin, O., Golge, S., Gomez, J., Hansen, J. -O., Holmstrom, T., Huang, J., Ibrahim, H., de Jager, C. W., Jensen, E., Jiang, X., Jones, M., Kang, H., Katich, J., Khanal, H. P., King, P. M., Korsch, W., LeRose, J., Lindgren, R., Lu, H. -J., Luo, W., Markowitz, P., Meziane, M., Michaels, R., Moffit, B., Monaghan, P., Muangma, N., Nanda, S., Norum, B. E., Pan, K., Parno, D., Piasetzky, E., Posik, M., Punjabi, V., Puckett, A. J. R., Qian, X., Qiang, Y., Qui, X., Riordan, S., Saha, A., Sawatzky, B., Shabestari, M., Shahinyan, A., Shoenrock, B., John, J. St., Subedi, R., Tobias, W. A., Tireman, W., Urciuoli, G. M., Wang, D., Wang, K., Wang, Y., Watson, J., Wojtsekhowski, B., Ye, Z., Zhan, X., Zhang, Y., Zheng, X., Zhao, B., and Zhu, L.
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Nuclear Experiment - Abstract
Due to the lack of free neutron targets, studies of the structure of the neutron are typically made by scattering electrons from either $^2$H or $^3$He targets. In order to extract useful neutron information from a $^3$He target, one must understand how the neutron in a $^3$He system differs from a free neutron by taking into account nuclear effects such as final state interactions and meson exchange currents. The target single spin asymmetry $A_y^0$ is an ideal probe of such effects, as any deviation from zero indicates effects beyond plane wave impulse approximation. New measurements of the target single spin asymmetry $A_y^0$ at $Q^2$ of 0.46 and 0.96 (GeV/$c)^2$ were made at Jefferson Lab using the quasi-elastic $^3\mathrm{He}^{\uparrow}(e,e'n)$ reaction. Our measured asymmetry decreases rapidly, from $>20\%$ at $Q^2=0.46$ (GeV/$c)^2$ to nearly zero at $Q^2=0.96$ (GeV$/c)^2$, demonstrating the fall-off of the reaction mechanism effects as $Q^2$ increases. We also observed a small $\epsilon$-dependent increase in $A_y^0$ compared to previous measurements, particularly at moderate $Q^2$. This indicates that upcoming high $Q^2$ measurements from the Jefferson Lab 12 GeV program can cleanly probe neutron structure from polarized $^3$He using plane wave impulse approximation., Comment: 6 pages, 5 figures
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- 2019
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44. Probing for high momentum protons in $^4$He via the $^4He(e,e'p)X$ reaction
- Author
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Iqbal, S., Benmokhtar, F., Ivanov, M., See, N., Aniol, K., Higinbotham, D. W., Boyd, C., Gadsby, A., Gilad, S., Saha, A., Udias, J. M., Goodwill, J. S., Finton, D., Boyer, A., Ye, Z., Solvignon, P., Aguilera, P., Ahmed, Z., Albataineh, H., Allada, K., Anderson, B., Anez, D., Annand, J., Arrington, J., Averett, T., Baghdasaryan, H., Bai, X., Beck, A., Beck, S., Bellini, V., Camsonne, A., Chen, C., Chen, J. -P., Chirapatpimol, K., Cisbani, E., Dalton, M. M., Daniel, A., Day, D., Deconinck, W., Defurne, M., Flay, D., Fomin, N., Friend, M., Frullani, S., Fuchey, E., Garibaldi, F., Gaskell, D., Gilman, R., Glamazdin, S., Gu, C., Gueye, P., Hanretty, C., Hansen, J. -O., Shabestari, M. Hashemi, Huang, M., Jin, G., Kalantarians, N., Kang, H., Kelleher, A., Korover, I., LeRose, J., Leckey, J., Lindgren, R., Long, E., Mammei, J., Margaziotis, D. J., Markowitz, P., Meekins, D., Meziani, Z., Michaels, R., Mihovilovic, M., Muangma, N., Camacho, C. Munoz, Norum, B., Nuruzzaman, Nuruzzaman, Pan, K., Phillips, S., Piasetzky, E., Pomerantz, I., Posik, M., Punjabi, V., Qian, X., Qiang, Y., Qiu, X., Reimer, P. E., Rakhman, A ., Riordan, S., Ron, G., Rondon-Aramayo, O., Selvy, L., Shahinyan, A., Shneor, R., Sirca, S., Slifer, K., Sparveris, N., Subedi, R., Sulkosky, V., Wang, D., Watson, J. W., Weinstein, L. B., Wojtsekhowski, B., Wood, S. A., Yaron, I., Zhan, X., Zhang, J., Zhang, Y. W., Zhao, B., Zheng, X., Zhu, P., and Zielinski, R.
- Subjects
Nuclear Experiment - Abstract
Experimental cross sections for the $^4He(e,e'p)X$ reaction up to a missing momentum of 0.632 GeV/$c$ at $x_B=1.24$ and $Q^2$=2(GeV/$c$)$^2$ are reported. The data are compared to Relativistic Distorted Wave Impulse Approximation(RDWIA) calculations for $^4He(e,e'p)^3H$ channel. Significantly more events in the triton mass region are measured for $p_{m}$$>$0.45 GeV/$c$ than are predicted by the theoretical model, suggesting that the effects of initial-state multi-nucleon correlations are stronger than expected by the RDWIA model., Comment: Submitted to PRC
- Published
- 2019
45. High Precision Measurement of Compton Scattering in the 5 GeV region
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Ambrozewicz, P., Ye, L., Prok, Y., Larin, I., Ahmidouch, A., Baker, K., Baturin, V., Benton, L., Bernstein, A., Burkert, V., Clinton, E., Cole, P. L., Collins, P., Dale, D., Danagoulian, S., Davidenko, G., Demirchyan, R., Deur, A., Dolgolenko, A., Dutta, D., Dzyubenko, G., Evdokimov, A., Fedotov, G., Feng, J., Gabrielyan, M., Gan, L., Gao, H., Gasparian, A., Gevorkyan, N., Gevorkyan, S., Glamazdin, A., Goryachev, V., Guo, L., Gyurjyan, V., Hardy, K., He, J., Isupov, E., Ito, M., Jiang, L., Kang, H., Kashy, D., Khandaker, M., Kingsberry, P., Klein, F., Kolarkar, A., Konchatnyi, M., Korchin, O., Korsch, W., Kosinov, O., Kowalski, S., Kubantsev, M., Kubarovsky, A., Kubarovsky, V., Lawrence, D., Li, X., Levillain, M., Lu, H., Ma, L., Martel, P., Matveev, V., McNulty, D., Mecking, B., Micherdzinska, A., Milbrath, B., Minehart, R., Miskimen, R., Mochalov, V., Morrison, B., Mtingwa, S., Nakagawa, I., Overby, S., Pasyuk, E., Payen, M., Park, K., Pedroni, R, Phelps, W., Protopopescu, D., Rimal, D., Ritchie, B. G., Romanov, D., Salgado, C, Shahinyan, A., Sitnikov, A, Sober, D., Stepanyan, S., Stephens, W., Tarasov, V., Taylor, S., Teymurazyan, A., Underwood, J., Vasiliev, A., Vishnyakov, V., Weygand, D. P., Wood, M., Zhang, Y., Zhou, S., and Zihlmann, B.
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Nuclear Experiment ,High Energy Physics - Phenomenology ,Nuclear Theory - Abstract
The cross section of atomic electron Compton scattering $\gamma + e \rightarrow \gamma^\prime + e^\prime $ was measured in the 4.40--5.475 GeV photon beam energy region by the {\em PrimEx} collaboration at Jefferson Lab with an accuracy of 2\% and less. The results are consistent with theoretical predictions that include next-to-leading order radiative corrections. The measurements provide the first high precision test of this elementary QED process at beam energies greater than 0.1 GeV., Comment: 6 pages, 4 figures
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- 2019
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46. Diffuse Radio Emission from Galaxy Clusters
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van Weeren, R. J., de Gasperin, F., Akamatsu, H., Brüggen, M., Feretti, L., Kang, H., Stroe, A., and Zandanel, F.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
In a growing number of galaxy clusters diffuse extended radio sources have been found. These sources are not directly associated with individual cluster galaxies. The radio emission reveal the presence of cosmic rays and magnetic fields in the intracluster medium (ICM). We classify diffuse cluster radio sources into radio halos, cluster radio shocks (relics), and revived AGN fossil plasma sources. Radio halo sources can be further divided into giant halos, mini-halos, and possible `intermediate' sources. Halos are generally positioned at cluster center and their brightness approximately follows the distribution of the thermal ICM. Cluster radio shocks (relics) are polarized sources mostly found in the cluster's periphery. They trace merger induced shock waves. Revived fossil plasma sources are characterized by their radio steep-spectra and often irregular morphologies. In this review we give an overview of the properties of diffuse cluster radio sources, with an emphasis on recent observational results. We discuss the resulting implications for the underlying physical acceleration processes that operate in the ICM, the role of relativistic fossil plasma, and the properties of ICM shocks and magnetic fields. We also compile an updated list of diffuse cluster radio sources which will be available on-line http://galaxyclusters.com. We end this review with a discussion on the detection of diffuse radio emission from the cosmic web., Comment: To appear in Space Science Reviews, 56 pages, 31 figures; For associated data see http://galaxyclusters.com
- Published
- 2019
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47. Non-competes, business dynamism, and concentration: Evidence from a Florida case study
- Author
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Kang, H and Fleming, L
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business concentration ,business dynamism ,employee mobility ,entrepreneurship ,firm sorting ,non-compete agreement ,Applied Economics ,Economics - Abstract
Most research on non-competes has focused on employees; here we study how non-competes affect firm location choice, growth, and consequent regional concentration, using Florida's 1996 legislative change that eased restrictions on their enforcement. Difference-in-differences models show that following the change, establishments of large firms were more likely to enter Florida; they also created a greater proportion of jobs and increased their share of employment in the state. Entrepreneurs or establishments of small firms, in contrast, were less likely to enter Florida following the law change; they also created a smaller proportion of new jobs and decreased their share of employment. Consistent with these location and job creation dynamics, regional business concentration increased following the law change in Florida. Nationwide cross-sections demonstrate consistent correlations between state-level non-compete enforcement and the location, employment, and concentration dynamics illustrated in Florida.
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- 2020
48. Targeted therapy for advanced salivary gland carcinoma based on molecular profiling: results from MyPathway, a phase IIa multiple basket study
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Kurzrock, R, Bowles, DW, Kang, H, Meric-Bernstam, F, Hainsworth, J, Spigel, DR, Bose, R, Burris, H, Sweeney, CJ, Beattie, MS, Blotner, S, Schulze, K, Cuchelkar, V, and Swanton, C
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Oncology and Carcinogenesis ,Cancer ,Clinical Research ,Digestive Diseases ,Evaluation of treatments and therapeutic interventions ,6.1 Pharmaceuticals ,Good Health and Well Being ,Antineoplastic Combined Chemotherapy Protocols ,Breast Neoplasms ,Carcinoma ,Humans ,Molecular Targeted Therapy ,Receptor ,ErbB-2 ,Salivary Gland Neoplasms ,Salivary Glands ,Trastuzumab ,advanced salivary gland carcinoma ,targeted therapy ,HER2-positive ,pertuzumab ,trastuzumab ,molecular profiling ,Receptor ,erbB-2 ,Oncology & Carcinogenesis ,Clinical sciences ,Oncology and carcinogenesis - Abstract
BackgroundSystemic therapy options for salivary cancers are limited. MyPathway (NCT02091141), a phase IIa study, evaluates targeted therapies in non-indicated tumor types with actionable molecular alterations. Here, we present the efficacy and safety results for a subgroup of MyPathway patients with advanced salivary gland cancer (SGC) matched to targeted therapies based on tumor molecular characteristics.Patients and methodsMyPathway is an ongoing, multiple basket, open-label, non-randomized, multi-center study. Patients with advanced SGC received pertuzumab + trastuzumab (HER2 alteration), vismodegib (PTCH-1/SMO mutation), vemurafenib (BRAF V600 mutation), or atezolizumab [high tumor mutational burden (TMB)]. The primary endpoint is the objective response rate (ORR).ResultsAs of January 15, 2018, 19 patients with SGC were enrolled and treated in MyPathway (15 with HER2 amplification and/or overexpression and one each with a HER2 mutation without amplification or overexpression, PTCH-1 mutation, BRAF mutation, and high TMB). In the 15 patients with HER2 amplification/overexpression (with or without mutations) who were treated with pertuzumab + trastuzumab, 9 had an objective response (1 complete response, 8 partial responses) for an ORR of 60% (9.2 months median response duration). The clinical benefit rate (defined by patients with objective responses or stable disease >4 months) was 67% (10/15), median progression-free survival (PFS) was 8.6 months, and median overall survival was 20.4 months. Stable disease was observed in the patient with a HER2 mutation (pertuzumab + trastuzumab, n = 1/1, PFS 11.0 months), and partial responses in patients with the PTCH-1 mutation (vismodegib, n = 1/1, PFS 14.3 months), BRAF mutation (vemurafenib, n = 1/1, PFS 18.5 months), and high TMB (atezolizumab, n = 1/1, PFS 5.5+ months). No unexpected toxicity occurred.ConclusionsOverall, 12 of 19 patients (63%) with advanced SGC, treated with chemotherapy-free regimens matched to specific molecular alterations, experienced an objective response. Data from MyPathway suggest that matched targeted therapy for SGC has promising efficacy, supporting molecular profiling in treatment determination.
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- 2020
49. Chandra Observations of the Spectacular A3411-12 Merger Event
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Andrade-Santos, F, Van Weeren, RJ, Di Gennaro, G, Wittman, D, Ryu, D, Lal, DV, Placco, VM, Fogarty, K, Jee, MJ, Stroe, A, Sobral, D, Forman, WR, Jones, C, Kraft, RP, Murray, SS, Brüggen, M, Kang, H, Santucci, R, Golovich, N, and Dawson, W
- Subjects
galaxies: clusters: general ,galaxies: clusters: individual ,galaxies: clusters: intracluster medium ,astro-ph.HE ,astro-ph.GA ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry ,Astronomy & Astrophysics ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) - Abstract
We present deep Chandra observations of A3411-12, a remarkable merging cluster that hosts the most compelling evidence for electron reacceleration at cluster shocks to date. Using the YX-M scaling relation, we find r 500 ∼ 1.3 Mpc, M500 =(7.1 ± 0.7) × 1014 M⊙, kT =6.5 ± 0.1 keV, and a gas mass of Mg,500 =(9.7 ± 0.1) × 1013 M⊙. The gas mass fraction within r 500 is fg = 0.14 ± 0.01. We compute the shock strength using density jumps to conclude that the Mach number of the merging subcluster is small (M ≤ 1.15-0.09+0.14). We also present density, temperature, pseudo-pressure, and pseudo-entropy maps. Based on the pseudo-entropy map, we conclude that the cluster is undergoing a mild merger, consistent with the small Mach number. On the other hand, radio relics extend over Mpc scale in the A3411-12 system, which strongly suggests that a population of energetic electrons already existed over extended regions of the cluster.
- Published
- 2019
50. Molecular insight into the lower critical solution temperature transition of aqueous alkyl phosphonium benzene sulfonates
- Author
-
Kang, H, Suich, DE, Davies, JF, Wilson, AD, Urban, JJ, and Kostecki, R
- Abstract
Ionic liquid (IL)-water mixtures can exhibit a lower critical solution temperature (LCST) transition, but changes in long-range order and local molecular environment during this transition are not comprehensively understood. Here we show that in IL-H2O LCST mixtures, the IL forms loosely held aggregate structures that grow in size leading up to a critical temperature, whereas the aggregation of a fully miscible aqueous mixture, obtained by minor chemical modification of the anion, decreases with increasing temperature. Radial distribution functions from molecular dynamics simulations support the observation of aggregation phenomena in the IL-H2O mixtures. A local molecular structure of the ions is derived from multi-dimensional NMR experiments in conjunction with reported molecular dynamics simulations. In addition to considerable shifts of water’s hydrogen bonding network in the fully miscible phase, by NMR we observe the anion’s protons response to the intermolecular thermal environment and the intramolecular environment and find that the responses are determined by the sulfonate ionic functional group.
- Published
- 2019
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