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AIM: To compare the change of anterior chamber angle(ACA)and vault value before and after implantable collamer lens(ICL)in two implant positions.METHODS: Randomized controlled study. A total of 83 patients(154 eyes)underwent ICL(V4c, 12.6mm)surgery from 2018 to 2019 were enrolled and divided into two randomly, including into horizontal group(79 eyes)and into vertical group(75 eyes). Pentacam was used to measure the ACA at 0°, 90°, 180°, 270° points before and after implantation and the ACA changes were calculated.RESULTS: After 12mo, the changes of ACA at 0°, 90°, 180°, 270° position were 15.3°±6.1°, 13.9°±6.3°, 16.5°±5.5° and 12.9°±6.0° in horizontal group while 12.9°±3.7°, 14.5°±6.8°, 14.3°±5.4° and 13.2°±5.9° in vertical group. There was a significant difference in ACA change at 0°-180° position between the two groups(P0.05). The vault value of the vertical group at 1mo was significantly different from that at 6mo and 12mo after implantation(P

AIM: To compare and analyze the changes of the anterior corneal surface, posterior surface and total corneal high-order aberration between femtosecond small incision lenticule extraction(SMILE)and implantable collamer lens(ICL)in the correction of moderate and low myopia. METHODS: Retrospective Study. Patients underwent SMILE surgery(n=35)or ICL surgery(n=35)with moderate or low myopia were selected in the refractive center of the Xi'an Aier Eye Hospital from November 2017 to February 2018. Before and 1, 3 and 6mo after surgery, the Scheimpflug phase formation based on Ray Tracing technology was applied to evaluate the anterior corneal surface, posterior surface and total corneal high-order aberration with a diameter of 6mm. Repeated measurement ANOVA was used to analyze the mean square root of corneal coma, spherical aberration and total high-order aberration at different time points. RESULTS: The post-surgery uncorrected visual acuity of both the SMILE group and the ICL group at 1, 3, and 6mo reached or exceeded the pre-surgery best corrected visual acuity, and the pre-surgery corneal aberrations of the two groups were not statistically significant(P>0.05). One month after surgery, the precorneal high-order aberration of the SMILE group was significantly increased(PP>0.05). Post-corneal aberration of the two groups was not statistically significant(P>0.05). After surgery, and the differences of coma, spherical aberration and total high-order aberration between the two groups were not significantly(P>0.05). CONCLUSION: Compared with SMILE surgery, precorneal high-order aberration induced by ICL is less for moderate and low myopia in the short term.

In the crystal structure of the title compound, C18H19N2O+·BF4−, bifurcated N—H...(F,F) hydrogen bonds link the protonated 4′-morpholinemethylbiphenyl-2-carbonitrile cations and slightly distorted tetrafluoroborate anions. π–π interactions [centroid–centroid distance = 3.805 (3) Å] help to consolidate the packing. The dihedral angle between the benzene rings in the cation is 57.24 (11)°.