1. Characteristics of the gut microbiota in pregnant women with fetal growth restriction
- Author
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Xinzhi Tu, Chun Duan, Bingying Lin, Kangfeng Li, Jie Gao, Huaying Yan, Kejian Wang, and Zhao Zhao
- Subjects
Fetal growth restriction (FGR) ,Gut microbiota ,16S rDNA sequencing ,Pregnant women ,Glycometabolism ,Gynecology and obstetrics ,RG1-991 - Abstract
Abstract Background Fetal growth restriction (FGR) in utero leads to failure of fetus to reach the genetically normal growth potential. Currently available means of treating FGR are limited. And it remains unknown how pregnant women who give birth to FGR fetus differ in gut microbiota composition from normal pregnant women. Methods In this case-control study, fecal samples were obtained from maternal rectum in the operation room by an obstetrician under strict aseptic conditions. We compared gut microbiota of 14 pregnant women with FGR and 18 normal controls by performing 16S rDNA amplicon sequencing. Results We identified significant differences in β-diversity between the FGR and control groups (P
- Published
- 2022
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