Search

Your search keyword '"Kanno, K."' showing total 795 results
Start Over Author "Kanno, K."
795 results on '"Kanno, K."'

1. Measurement of the mesonic decay branch of the $\bar{K}\!N\!N$ quasi-bound state

Author

Yamaga, T., Ajimura, S., Asano, H., Beer, G., Bhang, H., Bragadireanu, M., Buehler, P., Busso, L., Cargnelli, M., Choi, S., Curceanu, C., Enomoto, S., Fujioka, H., Fujiwara, Y., Fukuda, T., Guaraldo, C., Hashimoto, T., Hayano, R. S., Hiraiwa, T., Iio, M., Iliescu, M., Inoue, K., Ishiguro, Y., Ishikawa, T., Ishimoto, S., Itahashi, K., Iwai, M., Iwasaki, M., Kanno, K., Kato, K., Kato, Y., Kawasaki, S., Kienle, P., Kou, H., Ma, Y., Marton, J., Matsuda, Y., Mizoi, Y., Morra, O., Murayama, R., Nagae, T., Noumi, H., Ohnishi, H., Okada, S., Outa, H., Piscicchia, K., Sada, Y., Sakaguchi, A., Sakuma, F., Sato, M., Scordo, A., Sekimoto, M., Shi, H., Shirotori, K., Sirghi, D., Sirghi, F., Suzuki, S., Suzuki, T., Tanida, K., Tatsuno, H., Tokuda, M., Tomono, D., Toyoda, A., Tsukada, K., Doce, O. Vazquez, Widmann, E., Yamazaki, T., Yim, H., Zhang, Q., and Zmeskal, J.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

We conducted measurements of $K^- + {^3{\rm He}} \to \pi \!Y \!N + N'$ reactions using a $1~{\rm GeV}/c$ $K^-$-beam, with the objective of understanding the broad decay width of $\bar{K} \!N \!N$ (approximately twice as broad as that of $\Lambda(1405)$ considered to be the $\bar{K} \!N$ quasi-bound state). We successfully reproduced distributions of the $\pi \! Y \! N$ invariant mass and momentum transfer for $\pi \! Y \! N$ using model fitting functions for $\bar{K} \!N \!N$ formation and quasi-free $\bar{K}$ absorption (${\rm QF}_{\bar{K}-{\rm abs}}$) processes. The model can describe the experimental data quite well, and four $\bar{K} \! N \! N \to \pi \! Y \! N $ cross-sections were obtained. The results indicate that mesonic decay is the dominant decay branch of $\bar{K} \! N \! N$. The results also suggest that $\Gamma_{\pi \Lambda N} \sim \Gamma_{\pi \Sigma N}$, which indicates that the $I_{\bar{K} \! N}=1$ absorption channel, in addition to the $I_{\bar{K} \! N}=0$ absorption channel, substantially contribute to the $\bar{K} \! N \! N$ decay, making the $\bar{K} \! N \! N$ state approximately twice as unstable as $\Lambda$(1405).

Published
2024

2. Pole position of $\Lambda(1405)$ measured in $d(K^-,n)\pi\Sigma$ reactions

Author

Collaboration, J-PARC E31, Aikawa, S., Ajimura, S., Akaishi, T., Asano, H., Beer, G., Berucci, C., Bragadireanu, M., Buehler, P., Busso, L., Cargnelli, M., Choi, S., Curceanu, C., Enomoto, S., Fujioka, H., Fujiwara, Y., Fukuda, T., Guaraldo, C., Hashimoto, T., Hayano, R. S., Hiraiwa, T., Iio, M., Iliescu, M., Inoue, K., Ishiguro, Y., Ishimoto, S., Ishikawa, T., Itahashi, K., Iwai, M., Iwasaki, M., Kanno, K., Kato, K., Kato, Y., Kawasaki, S., Kienle, P., Komatsu, Y., Kou, H., Ma, Y., Marton, J., Matsuda, Y., Mizoi, Y., Morra, O., Murayama, R., Nagae, T., Noumi, H., Ohnishi, H., Okada, S., Omar, Z., Outa, H., Piscicchia, K., Sada, Y., Sakaguchi, A., Sakuma, F., Sato, M., Scordo, A., Sekimoto, M., Shi, H., Shirotori, K., Sirghi, D., Sirghi, F., Suzuki, K., Suzuki, S., Suzuki, T., Tanida, K., Tatsuno, H., Tokiyasu, A. O., Tokuda, M., Tomono, D., Toyoda, A., Tsukada, K., Vazquez-Doce, O., Widmann, E., Yamaga, T., Yamazaki, T., Yim, H., Zhang, Q., and Zmeskal, J.

Subjects
Nuclear Experiment
Abstract

We measured a set of $\pi^\pm\Sigma^\mp$, $\pi^0\Sigma^0$, and $\pi^-\Sigma^0$ invariant mass spectra below and above the $\bar{K}N$ mass threshold in $K^-$-induced reactions on deuteron. We deduced the $S$-wave $\bar{K}N\rightarrow\pi\Sigma$ and $\bar{K}N\rightarrow\bar{K}N$ scattering amplitudes in the isospin 0 channel in the framework of a $\bar{K}N$ and $\pi\Sigma$ coupled channel. We find that a resonance pole corresponding to $\Lambda(1405)$ is located at 1417.7$^{+6.0}_{-7.4}$(fitting errors)$^{+1.1}_{-1.0}$(systematic errors) + $[-26.1^{+6.0}_{-7.9}$(fitting errors)$^{+1.7}_{-2.0}$(systematic errors)]$i$ MeV/$c^2$, closer to the $\bar{K}N$ mass threshold than the value determined by the Particle Data Group., Comment: 8 pages, 5 figures

Published
2022
Full Text
View/download PDF

3. Recent results and future prospects of kaonic nuclei at J-PARC

Author

Sakuma, F., Ajimura, S., Akaishi, T., Asano, H., Bazzi, M., Beer, G., Bhang, H., Bragadireanu, M., Buehler, P., Busso, L., Cargnelli, M., Choi, S., Clozza, A., Curceanu, C., Enomoto, S., Fujioka, H., Fujiwara, Y., Fukuda, T., Guaraldo, C., Hashimoto, T., Hayano, R. S., Hiraiwa, T., Iio, M., Iliescu, M., Inoue, K., Ishiguro, Y., Ishikawa, T., Ishimoto, S., Itahashi, K., Iwasaki, M., Iwai, M., Kanno, K., Kato, K., Kato, Y., Kawasaki, S., Kienle, P., Kou, H., Ma, Y., Marton, J., Matsuda, Y., Miliucci, M., Mizoi, Y., Morra, O., Murayama, R., Nagae, T., Noumi, H., Ohnishi, H., Okada, S., Outa, H., Ozawa, K., Piscicchia, K., Sada, Y., Sakaguchi, A., Sato, M., Scordo, A., Sekimoto, M., Shi, H., Shirotori, K., Simon, M., Sirghi, D., Sirghi, F., Suzuki, S., Suzuki, T., Tanida, K., Tatsuno, H., Tokuda, M., Tomono, D., Toyoda, A., Tsukada, K., Doce, O. Vázquez, Widmann, E., Yamaga, T., Yamazaki, T., Yoshida, C., Zhang, Q., and Zmeskal, J.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

$\bar K$-nuclear bound systems, kaonic nuclei, have been widely discussed as products of the strongly attractive $\bar K N$ interaction in $I = 0$ channels. Recently, we demonstrated that kaonic nuclei can be produced via in-flight $(K^-,N)$ reactions using the low-momentum DC kaon beam at the J-PARC E15 experiment. We observed the simplest kaonic nuclei, $K^-pp$, having a much deeper binding energy than normal nuclei. For further studies, we have proposed a series of experimental programs for the systematic investigation of light kaonic nuclei, from $\bar K N$ ($\Lambda(1405)$) to $\bar K NNNN$. In the new experiment approved as J-PARC E80, we will measure the $\bar K NNN$ ($A=3$) system as a first step toward a comprehensive study., Comment: 10 pages, 5 figures, proceedings of the 8th Asia-Pacific Conference on Few-Body Problems in Physics (APFB2020), accepted for publication in Fwe-Body Systems

Published
2021
Full Text
View/download PDF

4. Construction of gas electron multiplier tracker for the J-PARC E16 experiment

Author

Murakami, T.N., Aoki, K., Ashikaga, S., En’yo, H., Gunji, T., Hamagaki, H., Ichikawa, M., Kanno, K., Kobayashi, S., Komatsu, Y., Kondo, T.K., Morino, Y., Murakami, H., Muto, R., Nakai, W., Nakasuga, S., Naruki, M., Obara, Y., Ozawa, K., Sekimoto, M., Shibukawa, T., Shigaki, K., Suzuki, K.N., Takagi, A., Takahashi, T.N., Watanabe, Y-S., and Yokkaichi, S.

Published
2024
Full Text
View/download PDF

5. Observation of a $\bar{K}NN$ bound state in the $^3{\rm He} (K^-, \Lambda p)n$ reaction

Author

Yamaga, T., Ajimura, S., Asano, H., Beer, G., Bhang, H., Bragadireanu, M., Buehler, P., Busso, L., Cargnelli, M., Choi, S., Curceanu, C., Enomoto, S., Fujioka, H., Fujiwara, Y., Fukuda, T., Guaraldo, C., Hashimoto, T., Hayano, R. S., Hiraiwa, T., Iio, M., Iliescu, M., Inoue, K., Ishiguro, Y., Ishikawa, T., Ishimoto, S., Itahashi, K., Iwai, M., Iwasaki, M., Kanno, K., Kato, K., Kato, Y., Kawasaki, S., Kienle, P., Kou, H., Ma, Y., Marton, J., Matsuda, Y., Mizoi, Y., Morra, O., Nagae, T., Noumi, H., Ohnishi, H., Okada, S., Outa, H., Piscicchia, K., Sada, Y., Sakaguchi, A., Sakuma, F., Sato, M., Scordo, A., Sekimoto, M., Shi, H., Shirotori, K., Sirghi, D., Sirghi, F., Suzuki, S., Suzuki, T., Tanida, K., Tatsuno, H., Tokuda, M., Tomono, D., Toyoda, A., Tsukada, K., Doce, O. Vazquez, Widmann, E., Yamazaki, T., Yim, H., Zhang, Q., and Zmeskal, J.

Subjects
Nuclear Experiment
Abstract

We have performed an exclusive measurement of the $K^{-}+\! ~^{3}{\rm He} \to \Lambda pn$ reaction at an incident kaon momentum of $1\ {\rm GeV}/c$.In the $\Lambda p$ invariant mass spectrum, a clear peak was observed below the mass threshold of $\bar{K}\!+\!N\!+\!N$, as a signal of the kaonic nuclear bound state, $\bar{K}NN$.The binding energy, decay width, and $S$-wave Gaussian reaction form-factor of this state were observed to be $B_{K} = 42\pm3({\rm stat.})^{+3}_{-4}({\rm syst.})\ {\rm MeV}$, $\Gamma_{K} = 100\pm7({\rm stat.})^{+19}_{-9}({\rm syst.})\ {\rm MeV}$, and $Q_{K} = 383\pm11({\rm stat.})^{+4}_{-1}({\rm syst.})\ {\rm MeV}/c$, respectively. The total production cross-section of $\bar{K}NN$, determined by its $\Lambda p$ decay mode, was $\sigma^{tot}_{K} \cdot BR_{\Lambda p} = 9.3\pm0.8({\rm stat.})^{+1.4}_{-1.0}({\rm syst.})\ \mu{\rm b}$.We estimated the branching ratio of the $\bar{K}NN$ state to the $\Lambda p$ and $\Sigma^{0}p$ decay modes as $BR_{\Lambda p}/BR_{\Sigma^{0}p} \sim 1.7$, by assuming that the physical processes leading to the $\Sigma N\!N$ final states are analogous to those of $\Lambda pn$., Comment: 13 pages, 12 figures

Published
2020
Full Text
View/download PDF

6. '$\mathbf{{\textit K^-}{\textit p}{\textit p}}$', a ${\overline{K}}$-Meson Nuclear Bound State, Observed in $^{3}{\rm He}({K^-}, {\Lambda} p)n$ Reactions

Author

collaboration, J-PARC E15, Ajimura, S., Asano, H., Beer, G., Berucci, C., Bhang, H., Bragadireanu, M., Buehler, P., Busso, L., Cargnelli, M., Choi, S., Curceanu, C., Enomoto, S., Fujioka, H., Fujiwara, Y., Fukuda, T., Guaraldo, C., Hashimoto, T., Hayano, R. S., Hiraiwa, T., Iio, M., Iliescu, M., Inoue, K., Ishiguro, Y., Ishikawa, T., Ishimoto, S., Itahashi, K., Iwasaki, M., Kanno, K., Kato, K., Kato, Y., Kawasaki, S., Kienle, P., Kou, H., Ma, Y., Marton, J., Matsuda, Y., Mizoi, Y., Morra, O., Nagae, T., Noumi, H., Ohnishi, H., Okada, S., Outa, H., Piscicchia, K., Sada, Y., Sakaguchi, A., Sakuma, F., Sato, M., Scordo, A., Sekimoto, M., Shi, H., Shirotori, K., Sirghi, D., Sirghi, F., Suzuki, K., Suzuki, S., Suzuki, T., Tanida, K., Tatsuno, H., Tokuda, M., Tomono, D., Toyoda, A., Tsukada, K., Doce, O. Vazquez, Widmann, E., Yamaga, T., Yamazaki, T., Zhang, Q., and Zmeskal, J.

Subjects
Nuclear Experiment
Abstract

We observed a distinct peak in the $\Lambda p$ invariant mass spectrum of $^{3}{\rm He}(K^-, \, \Lambda p)n$, well below the mass threshold of $m_K + 2 m_p$. By selecting a relatively large momentum-transfer region $q = 350 \sim 650$ MeV/$c$, one can clearly separate the peak from the quasi-free process, $\overline{K}N \rightarrow \overline{K}N$ followed by the non-resonant absorption by the two spectator-nucleons $\overline{K}NN \rightarrow \Lambda N $. We found that the simplest fit to the observed peak gives us a Breit-Wigner pole position at $B_{\rm {\it Kpp}} = 47 \pm 3 \, (stat.) \,^{+3}_{-6} \,(sys.)$ MeV having a width $\Gamma_{\rm {\it Kpp}} = 115 \pm 7 \, (stat.) \,^{+10}_{-9} \,(sys.)$ MeV, and the $S$-wave Gaussian reaction form-factor parameter $Q_{\rm {\it Kpp}} = 381 \pm 14 \, (stat.)\,^{+57}_{-0} \,(sys.)$ MeV/$c$, as a new form of the nuclear bound system with strangeness -- "$K^-pp$"., Comment: 17 pages, 4 figures

Published
2018

7. Safety and efficacy of oral semaglutide versus dulaglutide in Japanese patients with type 2 diabetes (PIONEER 10): an open-label, randomised, active-controlled, phase 3a trial

Author

Arisaka, T, Asakura, T, Azuma, N, Fukuda, S, Fukushima, Y, Harada, N, Inoue, S, Ishida, H, Ishii, H, Ishikawa, S, Jinnouchi, H, Kaneko, S, Kanno, K, Kato, M, Kato, Y, Kawada, T, Kim, H, Kiyosue, A, Matsuoka, O, Miho, O, Nakamoto, S, Nakamura, S, Nakanishi, S, Nishimura, H, Numata, A, Ohama, T, Okabe, T, Okuguchi, F, Osonoi, T, Sasaki, T, Seino, H, Shin, K, Shiraiwa, T, Sugiura, T, Wada, S, Yamauchi, A, Yabe, Daisuke, Nakamura, Jiro, Kaneto, Hideaki, Deenadayalan, Srikanth, Navarria, Andrea, Gislum, Mette, and Inagaki, Nobuya

Published
2020
Full Text
View/download PDF

10. Construction of gas electron multiplier tracker for the J-PARC E16 experiment

Author

Murakami, T.N., primary, Aoki, K., additional, Ashikaga, S., additional, En’yo, H., additional, Gunji, T., additional, Hamagaki, H., additional, Ichikawa, M., additional, Kanno, K., additional, Kobayashi, S., additional, Komatsu, Y., additional, Kondo, T.K., additional, Morino, Y., additional, Murakami, H., additional, Muto, R., additional, Nakai, W., additional, Nakasuga, S., additional, Naruki, M., additional, Obara, Y., additional, Ozawa, K., additional, Sekimoto, M., additional, Shibukawa, T., additional, Shigaki, K., additional, Suzuki, K.N., additional, Takagi, A., additional, Takahashi, T.N., additional, Watanabe, Y-S., additional, and Yokkaichi, S., additional

Published
2023
Full Text
View/download PDF

11. Pole position of Λ(1405) measured in d(K−,n)πΣ reactions

Author

Aikawa, S., primary, Ajimura, S., additional, Akaishi, T., additional, Asano, H., additional, Beer, G., additional, Berucci, C., additional, Bragadireanu, M., additional, Buehler, P., additional, Busso, L., additional, Cargnelli, M., additional, Choi, S., additional, Curceanu, C., additional, Enomoto, S., additional, Fujioka, H., additional, Fujiwara, Y., additional, Fukuda, T., additional, Guaraldo, C., additional, Hashimoto, T., additional, Hayano, R.S., additional, Hiraiwa, T., additional, Iio, M., additional, Iliescu, M., additional, Inoue, K., additional, Ishiguro, Y., additional, Ishimoto, S., additional, Ishikawa, T., additional, Itahashi, K., additional, Iwai, M., additional, Iwasaki, M., additional, Kanno, K., additional, Kato, K., additional, Kato, Y., additional, Kawasaki, S., additional, Kienle, P., additional, Komatsu, Y., additional, Kou, H., additional, Ma, Y., additional, Marton, J., additional, Matsuda, Y., additional, Mizoi, Y., additional, Morra, O., additional, Murayama, R., additional, Nagae, T., additional, Noumi, H., additional, Ohnishi, H., additional, Okada, S., additional, Omar, Z., additional, Outa, H., additional, Piscicchia, K., additional, Sada, Y., additional, Sakaguchi, A., additional, Sakuma, F., additional, Sato, M., additional, Scordo, A., additional, Sekimoto, M., additional, Shi, H., additional, Shirotori, K., additional, Sirghi, D., additional, Sirghi, F., additional, Suzuki, K., additional, Suzuki, S., additional, Suzuki, T., additional, Tanida, K., additional, Tatsuno, H., additional, Tokiyasu, A.O., additional, Tokuda, M., additional, Tomono, D., additional, Toyoda, A., additional, Tsukada, K., additional, Vazquez-Doce, O., additional, Widmann, E., additional, Yamaga, T., additional, Yamazaki, T., additional, Yim, H., additional, Zhang, Q., additional, and Zmeskal, J., additional

Published
2023
Full Text
View/download PDF

12. Commissioning Runs of J-PARC E16 Experiment

Author

Ichikawa, M., primary, Aoki, K., additional, Arimizu, D., additional, Ashikaga, S., additional, Chang, W.-C., additional, Chujo, T., additional, Ebata, K., additional, En’yo, H., additional, Esumi, S., additional, Hamagaki, H., additional, Honda, R., additional, Kajikawa, S., additional, Kanno, K., additional, Kimura, Y., additional, Kiyomichi, A., additional, Kondo, T.K., additional, Kyan, S., additional, Lin, C.-H., additional, Lin, C.-S., additional, Morino, Y., additional, Murakami, H., additional, Murakami, T.N., additional, Muto, R., additional, Nakai, W., additional, Nakasuga, S., additional, Naruki, M., additional, Nonaka, T., additional, Noumi, H., additional, Ozawa, K., additional, Sakaguchi, T., additional, Sako, H., additional, Sakuma, F., additional, Sato, S., additional, Sawada, S., additional, Sekimoto, M., additional, Shigaki, K., additional, Shirotori, K., additional, Sugimura, H., additional, Takahashi, T.N., additional, Takaura, Y., additional, Tatsumi, R., additional, Tsukui, K., additional, Wang, P.-H., additional, Yahiro, K., additional, Yamaguchi, K.H., additional, and Yokkaichi, S., additional

Published
2023
Full Text
View/download PDF

19. Towards the Measurement of the Mass Modifications of Vector Mesons in a Finite Density Matter

Author

Ozawa, K., primary, Aoki, K., additional, Arimizu, D., additional, Ashikaga, S., additional, Chang, W.C., additional, Chujo, T., additional, Ebata, K., additional, En'yo, H., additional, Esumi, S., additional, Hamagaki, H., additional, Honda, R., additional, Ichikawa, M., additional, Kajikawa, S., additional, Kanno, K., additional, Kimura, Y., additional, Kiyomichi, A., additional, Kondo, T.K., additional, Kyan, S., additional, Lin, C.H., additional, Lin, C.S., additional, Morino, Y., additional, Murakami, H., additional, Murakami, T.N., additional, Muto, R., additional, Nakai, W., additional, Nakasuga, S., additional, Naruki, M., additional, Nonaka, T., additional, Noumi, H., additional, Sakaguchi, T., additional, Sako, H., additional, Sakuma, F., additional, Sato, S., additional, Sawada, S., additional, Sekimoto, M., additional, Shigaki, K., additional, Shirotori, K., additional, Sugimura, H., additional, Takahashi, T.N., additional, Takaura, Y., additional, Tatsumi, R., additional, Tsukui, K., additional, Wang, P.H., additional, Yahiro, K., additional, Yamaguchi, K.H., additional, and Yokkaichi, S., additional

Published
2022
Full Text
View/download PDF

20. Pole position of $Λ(1405)$ measured in $d(K^-,n)πΣ$ reactions

Author

PARC E31 Collaboration, Aikawa, S., Ajimura, S., Akaishi, T., Asano, H., Beer, G., Berucci, C., Bragadireanu, M., Buehler, P., Busso, L., Cargnelli, M., Choi, S., Curceanu, C., Enomoto, S., Fujioka, H., Fujiwara, Y., Fukuda, T., Guaraldo, C., Hashimoto, T., Hayano, R. S., Hiraiwa, T., Iio, M., Iliescu, M., Inoue, K., Ishiguro, Y., Ishimoto, S., Ishikawa, T., Itahashi, K., Iwai, M., Iwasaki, M., Kanno, K., Kato, K., Kato, Y., Kawasaki, S., Kienle, P., Komatsu, Y., Kou, H., Ma, Y., Marton, J., Matsuda, Y., Mizoi, Y., Morra, O., Murayama, R., Nagae, T., Noumi, H., Ohnishi, H., Okada, S., Omar, Z., Outa, H., Piscicchia, K., Sada, Y., Sakaguchi, A., Sakuma, F., Sato, M., Scordo, A., Sekimoto, M., Shi, H., Shirotori, K., Sirghi, D., Sirghi, F., Suzuki, K., Suzuki, S., Suzuki, T., Tanida, K., Tatsuno, H., Tokiyasu, A. O., Tokuda, M., Tomono, D., Toyoda, A., Tsukada, K., Vazquez-Doce, O., Widmann, E., Yamaga, T., Yamazaki, T., Yim, H., Zhang, Q., and Zmeskal, J.

Subjects
FOS: Physical sciences, Nuclear Experiment (nucl-ex)
Abstract

We measured a set of $π^\pmΣ^\mp$, $π^0Σ^0$, and $π^-Σ^0$ invariant mass spectra below and above the $\bar{K}N$ mass threshold in $K^-$-induced reactions on deuteron. We deduced the $S$-wave $\bar{K}N\rightarrowπΣ$ and $\bar{K}N\rightarrow\bar{K}N$ scattering amplitudes in the isospin 0 channel in the framework of a $\bar{K}N$ and $πΣ$ coupled channel. We find that a resonance pole corresponding to $Λ(1405)$ is located at 1417.7$^{+6.0}_{-7.4}$(fitting errors)$^{+1.1}_{-1.0}$(systematic errors) + $[-26.1^{+6.0}_{-7.9}$(fitting errors)$^{+1.7}_{-2.0}$(systematic errors)]$i$ MeV/$c^2$, closer to the $\bar{K}N$ mass threshold than the value determined by the Particle Data Group., 8 pages, 5 figures

Published
2022
Full Text
View/download PDF

21. Efficacy and safety of sitagliptin treatment in older adults with moderately controlled type 2 diabetes: the STREAM study.

Author

Nagao, Mototsugu, Sasaki, Jun, Sugihara, Hitoshi, Tanimura-Inagaki, Kyoko, Harada, Taro, Sakuma, Ichiro, Oikawa, Shinichi, STREAM Study Investigators, Asano, T., Aoyama, S., Fukushima, T., Yan, J., Hasegawa, O., Hosokawa, K., Ishimaru, Y., Kaito, H., Kanbara, R., Kanno, K., Kimura, K., and Moritani, S.

Subjects
SITAGLIPTIN, TYPE 2 diabetes, OLDER people, CYSTATIN C, SAFETY, BLOOD sugar, OLDER patients
Abstract

Sitagliptin has been suggested as a treatment option for older adults with type 2 diabetes (T2D). However, no randomized controlled trial has been performed to evaluate the efficacy and safety of sitagliptin treatment in older Japanese patients with T2D. The STREAM study was a multicenter, open-label, randomized controlled trial. T2D outpatients aged 65–80 years with moderately controlled glycemic levels (HbA1c 7.4–10.4%) under lifestyle interventions without or with oral anti-diabetic drugs excluding DPP4 inhibitors or GLP-1 receptor agonists were recruited (n = 176). The participants were randomized into sitagliptin group (n = 88) who received sitagliptin as an initial or an additive anti-diabetic drug and control group (n = 88) who did not. The treatment goal was HbA1c level < 7.4%. Efficacy and safety during 12-month treatment period were investigated. The mean (± SD) ages were 70.6 ± 3.9 and 71.9 ± 4.4 years old in sitagliptin and control groups, respectively. According to a mixed-effects model analysis, average changes from baseline over the treatment period in fasting plasma glucose (FPG), HbA1c, and glycated albumin (GA) were − 27.2 mg/dL, − 0.61%, and − 2.39%, respectively, in sitagliptin group, and 0.50 mg/dL, − 0.29%, and − 0.93%, respectively, in control group. The reductions in FPG, HbA1c, and GA were significantly greater in sitagliptin group (P < 0.0001, P < 0.01, and P < 0.0001, respectively). There were no differences in the incidence of adverse effects, except for cystatin C elevation and platelet count reduction in sitagliptin group. Sitagliptin treatment effectively improved the glycemic profile without any serious adverse effects in older T2D patients. Trial registration number: UMIN000010376. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

29. Recent Results and Future Prospects of Kaonic Nuclei at J-PARC

Author

Sakuma, F., primary, Ajimura, S., additional, Akaishi, T., additional, Asano, H., additional, Bazzi, M., additional, Beer, G., additional, Bhang, H., additional, Bragadireanu, M., additional, Buehler, P., additional, Busso, L., additional, Cargnelli, M., additional, Choi, S., additional, Clozza, A., additional, Curceanu, C., additional, Enomoto, S., additional, Fujioka, H., additional, Fujiwara, Y., additional, Fukuda, T., additional, Guaraldo, C., additional, Hashimoto, T., additional, Hayano, R. S., additional, Hiraiwa, T., additional, Iio, M., additional, Iliescu, M., additional, Inoue, K., additional, Ishiguro, Y., additional, Ishikawa, T., additional, Ishimoto, S., additional, Itahashi, K., additional, Iwasaki, M., additional, Iwai, M., additional, Kanno, K., additional, Kato, K., additional, Kato, Y., additional, Kawasaki, S., additional, Kienle, P., additional, Kou, H., additional, Ma, Y., additional, Marton, J., additional, Matsuda, Y., additional, Miliucci, M., additional, Mizoi, Y., additional, Morra, O., additional, Murayama, R., additional, Nagae, T., additional, Noumi, H., additional, Ohnishi, H., additional, Okada, S., additional, Outa, H., additional, Ozawa, K., additional, Piscicchia, K., additional, Sada, Y., additional, Sakaguchi, A., additional, Sato, M., additional, Scordo, A., additional, Sekimoto, M., additional, Shi, H., additional, Shirotori, K., additional, Simon, M., additional, Sirghi, D., additional, Sirghi, F., additional, Suzuki, S., additional, Suzuki, T., additional, Tanida, K., additional, Tatsuno, H., additional, Tokuda, M., additional, Tomono, D., additional, Toyoda, A., additional, Tsukada, K., additional, Doce, O. Vázquez, additional, Widmann, E., additional, Yamaga, T., additional, Yamazaki, T., additional, Yoshida, C., additional, Zhang, Q., additional, and Zmeskal, J., additional

Published
2021
Full Text
View/download PDF

31. A case with sitosterolemia accompanied with macrothrombocytopenia and bilateral elbow tuberous xanthomas

Author

Okada, T., primary, Koseki, M., additional, Kato, H., additional, Tomita, K., additional, Tanaka, K., additional, Chang, J., additional, Inui, H., additional, Kanno, K., additional, Saga, A., additional, Ohama, T., additional, Kujiraoka, T., additional, Hattori, H., additional, Nishida, M., additional, Yamashita, S., additional, and Sakata, Y., additional

Published
2021
Full Text
View/download PDF

32. Diet-induced hepatic steatosis and fibrosis were improved by a selective ppara modulator, pemafibrate, in STZ -induced diabetic mice

Author

Chang, J., primary, Koseki, M., additional, Kanno, K., additional, Saga, A., additional, Okada, T., additional, Tanaka, K., additional, Kamada, Y., additional, Higo, T., additional, Okuzaki, D., additional, Inui, H., additional, Asaji, M., additional, Zhu, Y., additional, Ohama, T., additional, Nishida, M., additional, Yamashita, S., additional, and Sakata, Y., additional

Published
2021
Full Text
View/download PDF

37. Observation of a $\bar{K}NN$ bound state in the $^3{\rm He} (K^-, ��p)n$ reaction

Author

Yamaga, T., Ajimura, S., Asano, H., Beer, G., Bhang, H., Bragadireanu, M., Buehler, P., Busso, L., Cargnelli, M., Choi, S., Curceanu, C., Enomoto, S., Fujioka, H., Fujiwara, Y., Fukuda, T., Guaraldo, C., Hashimoto, T., Hayano, R. S., Hiraiwa, T., Iio, M., Iliescu, M., Inoue, K., Ishiguro, Y., Ishikawa, T., Ishimoto, S., Itahashi, K., Iwai, M., Iwasaki, M., Kanno, K., Kato, K., Kato, Y., Kawasaki, S., Kienle, P., Kou, H., Ma, Y., Marton, J., Matsuda, Y., Mizoi, Y., Morra, O., Nagae, T., Noumi, H., Ohnishi, H., Okada, S., Outa, H., Piscicchia, K., Sada, Y., Sakaguchi, A., Sakuma, F., Sato, M., Scordo, A., Sekimoto, M., Shi, H., Shirotori, K., Sirghi, D., Sirghi, F., Suzuki, S., Suzuki, T., Tanida, K., Tatsuno, H., Tokuda, M., Tomono, D., Toyoda, A., Tsukada, K., Doce, O. Vazquez, Widmann, E., Yamazaki, T., Yim, H., Zhang, Q., and Zmeskal, J.

Subjects
FOS: Physical sciences, High Energy Physics::Experiment, Nuclear Experiment (nucl-ex), Nuclear Experiment
Abstract

We have performed an exclusive measurement of the $K^{-}+\! ~^{3}{\rm He} \to ��pn$ reaction at an incident kaon momentum of $1\ {\rm GeV}/c$.In the $��p$ invariant mass spectrum, a clear peak was observed below the mass threshold of $\bar{K}\!+\!N\!+\!N$, as a signal of the kaonic nuclear bound state, $\bar{K}NN$.The binding energy, decay width, and $S$-wave Gaussian reaction form-factor of this state were observed to be $B_{K} = 42\pm3({\rm stat.})^{+3}_{-4}({\rm syst.})\ {\rm MeV}$, $��_{K} = 100\pm7({\rm stat.})^{+19}_{-9}({\rm syst.})\ {\rm MeV}$, and $Q_{K} = 383\pm11({\rm stat.})^{+4}_{-1}({\rm syst.})\ {\rm MeV}/c$, respectively. The total production cross-section of $\bar{K}NN$, determined by its $��p$ decay mode, was $��^{tot}_{K} \cdot BR_{��p} = 9.3\pm0.8({\rm stat.})^{+1.4}_{-1.0}({\rm syst.})\ ��{\rm b}$.We estimated the branching ratio of the $\bar{K}NN$ state to the $��p$ and $��^{0}p$ decay modes as $BR_{��p}/BR_{��^{0}p} \sim 1.7$, by assuming that the physical processes leading to the $��N\!N$ final states are analogous to those of $��pn$., 13 pages, 12 figures

Published
2020
Full Text
View/download PDF

48. 特別支援学校・特別支援学級に在籍する知的障害児童の保護者のメンタルヘルスと支援に関する調査研究

Author

SUGIOKA,C, HASHIMOTO,S, HAYASHI,A, KUMAGAI,R, TAGUCHI,T, KAWAIKE,J, MASU,C, KANNO,K, NISHINA,I, MIURA,T, SUGIOKA,C(Graduate School of Education, Tokyo Gakugei University), HASHIMOTO,S(Center for the Research and Support of Educational Practice, Tokyo Gakugei University), HAYASHI,A(Center for the Research and Support of Educational Practice, Tokyo Gakugei University), KUMAGAI,R(Graduate School of Education, Tokyo Gakugei University), TAGUCHI,T(Graduate School of Education, Tokyo Gakugei University), KAWAIKE,J(Graduate School of Education, Tokyo Gakugei University), MASU,C(Graduate School of Education, Tokyo Gakugei University), KANNO,K(Graduate School of Education, Tokyo Gakugei University), NISHINA,I(Graduate School of Education, Tokyo Gakugei University), and MIURA,T(Faculty of Human Studies, Taisho University)

Subjects
Mental Health, Support of Parents, Parents of Children with Intellectual Disabilities
Published
2016

Catalog

Books, media, physical & digital resources
See catalog results