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Rheumatoid factor (RF), anticyclic citrullinated peptides (Anti-CCP), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) are used as disease markers for rheumatoid arthritis (RA). However, correlation of disease activity score (DAS) 28 with autoantibodies and inflammatory markers has not been studied in detail. Here, we have made an attempt to determine the association of DAS-28 with autoantibodies and inflammatory markers among the North Indian population. Further, we investigated the potential of subsets of autoantibodies in RA diagnosis. Disease activity was calculated by DAS-28-ESR calculator and levels of disease markers were estimated in serum. We noticed positive correlation between DAS-28, CRP (r=0.63, p=0.00) and ESR (r=0.72, p=0.00). Moderate and weak correlation was found with RF (r=0.41, p=0.00) and anti-CCP (r=0.25, p=0.011), respectively. Patients with positive subsets of both autoantibodies (RF+/Anti-CCP+) have shown a positive correlation with DAS-28. In our study, we found that the presence of RF and Anti-CCP in patient sera can increase the early detection rate of disease. But, for the diagnosis of disease in seronegative patients, more studies on biomarkers are required. [ABSTRACT FROM AUTHOR]

This paper performs a systematic review of the research literature in the field of agritourism. In the study, using a structured literature review methodology, established as well as emerging research clusters have been identified for epistemological analysis. Such analysis helps in the identification of key research topics, interrelations, and collaboration patterns in the field of agritourism and other research areas involving similar concepts. Graphical mapping of the agritourism research field is done using visualization of similarities (VOS). VOS software analyzed bibliographic data of 459 research publications obtained from Web of Science and Scopus databases from a period of 1980–2019. This graphical mapping illustrated the authors' and countries' contributions, their collaboration, and publication pattern over the period. This paper gives insights about majorly studied research themes and also identified common areas of current research interest and potential directions for future research. [ABSTRACT FROM AUTHOR]

The article presents a case study of a 61-year-old male presented with complaints of pain over the left greater trochanter along with limping for 2 days, and he had no other comorbid conditions including joint or tendon problems. The article discuses that Fluoroquinolone-induced tendinopathy or tendon rupture is a rare side-effect, occurring in 0.14%–0.4% of otherwise healthy controls.