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We present the results of our power spectral density analysis for the BL Lac object OJ 287, utilizing the Fermi-LAT survey at high-energy γ-rays, Swift-XRT in X-rays, several ground-based telescopes and the Kepler satellite in the optical, and radio telescopes at GHz frequencies. The light curves are modeled in terms of continuous-time autoregressive moving average (CARMA) processes. Owing to the inclusion of the Kepler data, we were able to construct for the first time the optical variability power spectrum of a blazar without any gaps across ∼6 dex in temporal frequencies. Our analysis reveals that the radio power spectra are of a colored-noise type on timescales ranging from tens of years down to months, with no evidence for breaks or other spectral features. The overall optical power spectrum is also consistent with a colored noise on the variability timescales ranging from 117 years down to hours, with no hints of any quasi-periodic oscillations. The X-ray power spectrum resembles the radio and optical power spectra on the analogous timescales ranging from tens of years down to months. Finally, the γ-ray power spectrum is noticeably different from the radio, optical, and X-ray power spectra of the source: we have detected a characteristic relaxation timescale in the Fermi-LAT data, corresponding to ∼150 days, such that on timescales longer than this, the power spectrum is consistent with uncorrelated (white) noise, while on shorter variability timescales there is correlated (colored) noise. © 2018. The American Astronomical Society. All rights reserved..

Haumea-one of the four known trans-Neptunian dwarf planets- is a very elongated and rapidly rotating body1-3. In contrast to other dwarf planets4-6, its size, shape, albedo and density are not well constrained. The Centaur Chariklo was the first body other than a giant planet known to have a ring system7, and the Centaur Chiron was later found to possess something similar to Chariklo's rings8,9. Here we report observations from multiple Earth-based observatories of Haumea passing in front of a distant star (a multichord stellar occultation). Secondary events observed around the main body of Haumea are consistent with the presence of a ring with an opacity of 0.5, width of 70 kilometres and radius of about 2,287 kilometres. The ring is coplanar with both Haumea's equator and the orbit of its satellite Hi'iaka. The radius of the ring places it close to the 3:1 mean-motion resonance with Haumea's spin period-that is, Haumea rotates three times on its axis in the time that a ring particle completes one revolution. The occultation by the main body provides an instantaneous elliptical projected shape with axes of about 1,704 kilometres and 1,138 kilometres. Combined with rotational light curves, the occultation constrains the three-dimensional orientation of Haumea and its triaxial shape, which is inconsistent with a homogeneous body in hydrostatic equilibrium. Haumea's largest axis is at least 2,322 kilometres, larger than previously thought, implying an upper limit for its density of 1,885 kilograms per cubic metre and a geometric albedo of 0.51, both smaller than previous estimates1,10,11. In addition, this estimate of the density of Haumea is closer to that of Pluto than are previous estimates, in line with expectations. No global nitrogen- or methane-dominated atmosphere was detected. © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.

We analyse the light curve in the R band of the blazar OJ287, gathered during the 2015/2016 observing season. We did a search for quasi-periodic oscillations (QPOs) using several methods over a wide range of timescales. No statistically significant periods were found in the high-frequency domain both in the ground-based data and in Kepler observations. In the longer-period domain, the Lomb-Scargle periodogram revealed several peaks above the 99% significance level. The longest one-about 95 days-corresponds to the innermost stable circular orbit (ISCO) period of the more massive black hole. The 43-day period could be an alias, or it can be attributed to accretion in the form of a two-armed spiral wave. © 2016 by the authors.

Background/aims: We planned to determine irritable bowel syndrome prevalence in our region with its distribution according to clinical characteristics of patients and the factors which are considered to be related with irritable bowel syndrome. Methods: 998 of 1250 individuals (mean age 38.99+0.44) replied to our questionnaire including Rome II criteria. Results: We found the irritable bowel syndrome prevalence in the city center of Sivas to be 19.1%. Distribution of irritable bowel syndrome (+) patients age groups showed no significant difference but irritable bowel syndrome was significantly more common in females. The most common occupation showing irritable bowel syndrome positivity was workers. Irritable bowel syndrome prevalence was also significantly higher in persons not eating three regular meals per day. There was a significantly positive correlation between irritable bowel syndrome prevalence and psychological events, previous abdominal operations and infections. A change in bowel habitus was observed in 41.8% of irritable bowel syndrome patients, and the most common change was constipation. 39.8% of the irritable bowel syndrome patients had applied to the doctor, most often to doctors of internal medicine. We found the irritable bowel syndrome prevalence not to be related with educational status, smoking, daily tea and coffee consumption, alcohol intake, menstrual periods or weight loss. Conclusion: Irritable bowel syndrome prevalence in our region with its demographic characteristics was similar to the results seen in western countries.

WOS: 000289324100159 …

Malvasija dubrovačka je jedna od najkvalitetnijih južnih bijelih sorti u Hrvatskoj i zaslužuje najveću stručnu pozornost. Iako su proizvodnja grožđa i vinifikacija zahtjevniji nego kod većine drugih sorata, izuzetan kvalitativni potencijal čini je i gospodarski vrlo interesantnom. Ponajprije u proizvodnji desertnih vina (prošeka), ali i vina iz redovite berbe. Osim za svoje matično vinogorje (Konavosko), interesantna je sorta i za druga područja sličnih ekoloških karakteristika. U svim godinama provedbe projekta rezultati su potvrdili visoku reputaciju sorte i opravdali visoke zahtjeve i ciljeve postavljene pred projekt. Kao najvažniji možemo istaći da je sorta u potpunosti spašena od daljnjeg propadanja, te da će u slijedećim godinama ponovo zauzeti mjesto koje je u prošlosti imala – čuvena i najkvalitetnija dubrovačka vina proizvode se od ove sorte.

Serum levels of YKL-40, MMP-2 and MMP-9 in 27 patients with locally advanced breast carcinoma received neoadjuvant chemotherapy were measured. All patients underwent neoadjuvant chemotherapy named as FAC protocol (5-Fluorouracil, Doxorubicin and Cyclophosphamide) with 21 days interval. There was 26,7% decrease in mean serum YKL-40 levels (from 146,4 mu g/ml to 107,3 mu g/ml) in clinically responsive group. This level was almost unchanged in non-responsive group (P > 0, 05). There was 42, 1% decrease in mean serum YKL-40 levels (from 173,1 mu g/ml to 98, 8 mu g/ml) in pathologically responsive group. This decrease was more dramatic in patients with complete pathological response (70, 2%). However, this level was slightly increased in non-responsive group. Changes in serum levels of MMP-2 and MMP-9 were not found to be associated with tumor response. Serum measurement of YKL-40 can be a helpful tool to predict pathological tumor response in breast cancer patients with neoadjuvant chemotherapy but not MMP-2 and MMP-9.

Well-differentiated forms of thyroid cancer, including follicular carcinoma, usually have good prognoses. But they are also known to metastasize to the bones, lungs and central nervous system. Endobronchial metastasis is exceptionally rare. In this paper, we report on a patient with endobronchial metastasis of follicular thyroid carcinoma. A 77-year-old male patient presented to our hospital with hemoptysis and a growing mass over the right clavicula. Computerized tomography (CT) of the chest revealed multiple lung metastases. Flexible bronchoscopy revealed a fragile polypoid mass of 1.5 cm, 6 cm distal to the vocal cords. Biopsy from the supraclavicular mass was consistent with follicular thyroid carcinoma. Taking into account the advanced nature of the disease as well as the general condition and age of the patient, aggressive treatment modalities were not considered in the management. Palliation for hemoptysis was attained by external radiotherapy. After radiotherapy, hemoptysis did not recur, and the patient was discharged. Although endobronchial metastasis of thyroid follicular carcinoma is very rare, the presence of endobronchial metastasis may be life threatening due to massive hemoptysis, and such a lesion must be suspected in any cancer patients presenting with hemoptysis.