1. Non-coding RNA biosensors for early detection of brain cancer.
- Author
-
Karami Y, Ehtiati S, Ghasemi H, Rafiee M, Zamani Sani M, Hosseini SE, Moradi Kazerouni H, Movahedpour A, Aiiashi S, and Khatami SH
- Subjects
- Humans, Biomarkers, Tumor genetics, Biosensing Techniques methods, Brain Neoplasms genetics, Brain Neoplasms diagnosis, RNA, Untranslated genetics, RNA, Untranslated analysis, Early Detection of Cancer methods
- Abstract
Brain cancer remains a formidable challenge with limited treatment options. Non-coding RNAs (ncRNAs) have emerged as promising biomarkers due to their dysregulation in tumorigenesis. This review explores the potential of biosensors for early detection of brain cancer by targeting ncRNAs. We discuss the classification and functions of ncRNAs, emphasizing their involvement in key cancer-related processes. Additionally, we delve into recent advancements in biosensor technology, focusing on their ability to accurately detect specific ncRNA biomarkers associated with brain cancer. Our findings underscore the potential of biosensors to revolutionize brain cancer diagnosis, enabling personalized medicine and improving patient outcomes. Future research should focus on refining biosensor technology and expanding their clinical application., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.) more...
- Published
- 2025
- Full Text
- View/download PDF