143 results on '"Karan A. Patel"'
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2. Abstract 131: Trends in Cerebral Venous Thrombosis: Analysis of the National Inpatient Sample 2016‐2020
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Piers M. Klein, Liqi S. Shu, Muhammad M. Qureshi, Mohamad S. Abdalkader, Thalia E. Field, James W. Siegler, Lily P. Zhou, Karan A. Patel, Sami K. Al Kasab, Adam Y. de Havenon, Shadi Q. Qureshi, Adnan I. Qureshi, and Thanh N. Nguyen
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Neurology. Diseases of the nervous system ,RC346-429 ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Introduction Cerebral venous thrombosis (CVT) is an uncommon form of stroke with relatively low mortality but higher incidence in younger adults.1–3 Previous work has suggested decreased overall stroke hospitalization volumes, but preserved CVT hospitalization volumes and increased CVT mortality during the COVID‐19 pandemic.4,5 We sought to provide updated incidence and trend data for cerebral venous thrombosis (CVT) in the United States from 2016‐2020, examine the impact of the COVID‐19 pandemic on CVT, and identify predictors of in‐hospital mortality. Methods Validated ICD‐10 codes were used to identify patients with CVT in the National Inpatient Sample (NIS) between 2016 and 2020. The NIS is part of the Healthcare Cost and Utilization Project (HCUP) and is maintained the Agency for Healthcare Research and Quality. The NIS provides a stratified nationally representative 20% sample of all hospital discharges in the United States, excluding rehabilitation and long‐term acute care hospitals. Annual updates to the NIS are released approximately 20 months after the conclusion of the data year. Sample weights were applied to generate nationally representative estimates, and census data were used to compute incidence rates. The first wave of the COVID‐19 pandemic was defined as January‐May 2020. Predictor variables for mortality were selected based upon previous studies of incidence and outcomes of CVT and biological plausibility.6–8 Multivariable logistic regression was conducted using all predictor variables that achieved p
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- 2023
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3. Decoding the Signals: An Analysis of Preference Signaling in the 2023 Orthopaedic Surgery Residency Match
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David G. Deckey, MD, Eugenia Lin, MD, Coltin R.B. Gerhart, MS, Joseph C. Brinkman, MD, Karan A. Patel, MD, and Joshua S. Bingham, MD
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Orthopedic surgery ,RD701-811 - Abstract
Background:. While previously used in other specialties, the preference signaling program (PSP) was implemented in the 2022 to 2023 orthopaedic surgery residency application process for the first time. The PSP allowed for 30 signaling tokens to be sent by applicants to programs of their choice to indicate particular interest in a program. It remains unknown how the PSP affects applicants and programs in the orthopaedic surgery residency match. Thus, this study's purpose was to assess the utility of preference signaling within the orthopaedic surgery residency application process in its inaugural year of use. Methods:. An anonymous electronic survey was emailed to all orthopaedic surgery residency applicants who applied to the authors' institution during the 2022 to 2023 application cycle. The survey was sent after match lists were submitted and closed before the release of match results. The survey collected information regarding applicant demographics, preference signaling habits, and attitude toward preference signaling. Results:. The survey was completed by 101 applicants. Applicants applied to a mean of 90 programs (range: 10-197) and received an average of 12 interview invitations (range: 0-39). Applicants almost uniformly used all 30 signals, with nearly two-thirds signaling their home programs (65%, 49/76), and nearly all applicants sending signals to programs at which they performed away rotations (95.7%, 88/92). Applicants received a mean of 9 invitations from programs they signaled, compared with 2 invitations from programs they did not signal. Applicants were significantly more likely to receive an interview invite at a program they signaled than one they did not (p < 0.01). Overall, 57% of applicants (57/101) found the PSP to be helpful, whereas 28% (28/101) found it to be unhelpful, and 16% (16/101) had a neutral opinion. Conclusions:. This study reports that the PSP in the 2022 to 2023 orthopaedic surgery match was an effective method of expressing interest in a program because applicants were significantly more likely to receive interview invites to signaled programs. More than half of respondents felt PSP to be helpful; however, the effect on application numbers is still unclear. Level of Evidence:. III
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- 2023
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4. Increasing severity of anemia is associated with poorer 30-day outcomes for total shoulder arthroplasty
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Matthew K. Doan, BS, Jordan R. Pollock, BS, M. Lane Moore, BS, Jeffrey D. Hassebrock, MD, Justin L. Makovicka, MD, MBA, John M. Tokish, MD, and Karan A. Patel, MD
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Anemia ,Shoulder ,Arthroplasty ,Degenerative disease ,Osteoarthritis ,Outcomes ,Orthopedic surgery ,RD701-811 ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Background: Total shoulder arthroplasty (TSA) has increased in utilization over the past several decades. Anemia is a common preoperative condition among patients undergoing TSA and has been associated with poorer outcomes in other surgical procedures. To the best of our knowledge, no study has analyzed the association between anemia severity and TSA outcomes. Therefore, the purpose of this study is to determine the effects that increasing severity of anemia may have on the postoperative outcomes in patients receiving primary TSA. Methods: A retrospective analysis was performed using the American College of Surgeons National Surgery Quality Improvement Project database from the years 2015 to 2018. Current Procedure Terminology code 23472 was used to identify all primary TSA procedures recorded during this time frame. Patients with greater than 38% preoperative hematocrit (HCT) were classified as having normal HCT levels. Patients with HCT values between 33% and 38% were classified as having mild anemia. All patients with less than 33% HCT were classified as having moderate/severe anemia. Patient demographic information, preoperative risk factors, and postoperative outcomes were compared among the 3 cohorts. A multivariate logistic regression including demographic factors and comorbidities was performed to determine whether increasing severity of anemia is independently associated with poorer postoperative outcomes. Results: Of the 15,185 patients included in this study, 11,404 had normal HCT levels, 2962 patients were mildly anemic, and 819 patients had moderate to severe anemia. With increasing severity of anemia, there was an increased average hospital length of stay (1.6 vs. 2.1 vs. 3.0 days, P
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- 2021
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5. Publicly Available Pricing Information for Orthopaedic Upper Extremity Procedures in the United States Lacks Transparency and Consistency Between Major Hospitals
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M. Lane Moore, B.S., Jordan R. Pollock, B.S., Matthew K. Doan, B.S., Jack M. Haglin, B.S., Kelly L. Scott, M.D., M.P.H., Joshua S. Bingham, M.D., and Karan A. Patel, M.D.
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Sports medicine ,RC1200-1245 - Abstract
Purpose: The purpose of this study was to assess the price variation of various Medicare severity diagnosis-related group codes for orthopaedic upper extremity procedures for the top 20 orthopaedic hospitals using chargemaster price listings from each hospital. Methods: The top 20 orthopaedic hospitals in the United States were determined by querying the U.S. News and World Report’s 2020 orthopaedic hospital ranking. This report ranks orthopaedic hospitals according to 4 major domains: outcomes, structure, process/expert opinion, and patient experience. Chargemaster data for the top 20 orthopaedic hospitals was compiled from their websites. Five DRG codes that represented orthopaedic upper extremity procedures were selected, and the pricing information for each was extracted from hospital chargemasters. The median income and cost-of-living index were also compiled for the county that each hospital is located in so that pricing data could be compared to economic measures through regression analysis. Results: Of the top 20 orthopaedic hospitals, 18 had publicly available pricing information in DRG format on their websites. The DRG code with the highest pricing variability was Hand Injury Procedures (DRG 906; range, $12,832-$253,633). The procedure with the least pricing variability was Hand or Wrist Procedures (DRG 514; range, $24,533-$128,403). Additionally, only the cost of living index was a statistically significant predictor of procedure pricing with a weak correlation. Conclusion: Hospital chargemaster listings are lacking in 2 major areas: true price transparency and standardization/consistency between hospitals. Chargemaster data are often difficult to find, confusing to patients, and inaccurate. Additionally, the price range for a single DRG code can also vary substantially depending on the hospital. It is possible that hospitals located in areas with high costs of living and median incomes would charge higher prices, but these factors were not found to support this hypothesis.
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- 2022
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6. Top-100 Most-Cited Sports-Related Concussion Articles Focus on Symptomatology, Epidemiology, and Demographics
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Kade S. McQuivey, M.D., M. Lane Moore, B.S., Jordan R. Pollock, B.S., Jeffrey D. Hassebrock, M.D., Karan A. Patel, M.D., and Anikar Chhabra, M.D.
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Sports medicine ,RC1200-1245 - Abstract
Purpose: To analyze the top-100 cited articles on sports-related concussions together with a bibliometric analysis to determine citations by year, level of evidence, study design, and several other factors related to the top referenced articles in sports concussions. Methods: The Clarivate Analytics Web of Knowledge database was used to gather data using Boolean queries to capture all possible iterations of sports-related concussion research. Articles were organized in descending order based on the number of citations and included or excluded based on relevance to concussion. Collected information included author name, publication year, country of origin, journal name, article type, study focus, and the level of evidence. Results: The top-100 articles were cited 31,197 times with an average of 312.0 citations per publication. More than one half were published in 2006 or later (52). Cohort studies and descriptive articles were the most prevalent study types (22 each). Studies with Level V evidence were the most common (33). The most common areas of study were symptomatology (short term, long term) with 17 articles, followed by epidemiology/demographics with 16 articles. The least common area of study was concussion prevention (2 articles), followed by management/treatment, diagnostics (labs, imaging) with 4 articles each. Conclusions: We identified the most influential studies in sports-related concussion based on number of citations and citation density. A majority of these articles were published in the United States after 2006 and are most commonly cohort studies (Level IV evidence) and descriptive articles (Level V evidence). Current research focuses most heavily on the symptomatology and epidemiology/demographics of sports concussion. Clinical Relevance: This study serves to identify the most influential articles in sports-related concussion and identify research topics with general deficiencies within the field of sports-related concussion research.
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- 2021
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7. Orthopaedic Foot and Ankle Surgery Fellowship Directors Are Typically White Men in Their Early 50s With Strong Achievements in Research
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Muhammad Ali Elahi, B.S., M. Lane Moore, B.S., Matthew K. Doan, B.S., Jordan R. Pollock, B.S., Jeffrey D. Hassebrock, M.D., Justin L. Makovicka, M.D., M.B.A., Joseph C. Brinkman, M.D., and Karan A. Patel, M.D.
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Sports medicine ,RC1200-1245 - Abstract
Purpose: To determine the objective characteristics of orthopaedic foot and ankle fellowship directors (FDs) by concentrating on the demographic characteristics, academic background, institutional history, research experience, and professional affiliations of these leaders. Methods: Data for each FD were collected by searching institutional biographies, personal websites, or publicly available curricula vitae. Data collection included the following variables: age, sex, race/ethnicity, previous training institutions, residency and fellowship graduation years, advanced degrees, military affiliation, institutional loyalty, year hired, FD career timeline, total number of publications, total number of citations, and h-index. Results: Of the 47 FDs, 44 (93.6%) were men and 3 (6.4%) were women. The mean age was 50.8 ± 9.4 years. Most orthopaedic foot and ankle FDs were white (n = 42, 89.4%), followed by Asian (n = 4, 8.5%) and black or African American (n = 1, 2.1%). The mean Scopus h-index, total number of publications, and total number of citations for all foot and ankle FDs were 13.3 ± 9.5, 47.5 ± 45.8, and 898.1 ± 1,040.3, respectively. Among all foot and ankle FDs, the mean tenure in the FD position was 5.8 ± 4.6 years. Conclusions: Orthopaedic foot and ankle FDs are primarily white men in their 50s, with minimal female and minority representations. These FDs are distinguished by their high level of research productivity. Additionally, orthopaedic foot and ankle training backgrounds seem to play an important role, given that most of the appointed FDs trained in only a few select programs. Clinical Relevance: This study outlines some of the most important characteristics among foot and ankle FDs and identifies important disparities within this population of leaders that may have detrimental effects on the field.
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- 2021
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8. Personal Finance Primer for the Future Orthopaedic Surgeon: A Starting Point
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Austin J. Ramme, MD, PhD, Milan Patel, MD, Karan A. Patel, MD, William H. Montag, CFP, Anthony J. Schau, CFP, Stephan I. Sabo, BBA, and Asheesh Bedi, MD, FAOA
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Orthopedic surgery ,RD701-811 - Abstract
Abstract. The level of financial literacy varies among orthopaedic trainees. Personal finance ideally should be taught before accepting student loans; however, when this has not happened, it is imperative that trainees start taking their personal finances seriously. Many trainees are faced with large amounts of student debt and struggle with how to manage a large salary increase in their first job. This can lead to poor financial decisions including insufficient savings. The authors provide a comprehensive viewpoint on personal finance for the orthopaedic trainee. In this article, we provide future orthopaedic surgeons with a framework for personal financial management as a starting point to understanding the financial concepts of budgeting, investment, debt management, mortgage, disability insurance, and life insurance.
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- 2021
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9. Comparison of Microfracture with Extracellular Matrix Augmentation and Osteochondral Autograft Transplantation for the Treatment of Medium-Size Osteochondral Lesions of the Talus
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Oliver B. Hansen, Stephanie K. Eble, Taylor Cabe BA, Karan A. Patel, Jonathan T. Deland MD, Carolyn M. Sofka MD, FACR, and Mark C. Drakos MD
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Orthopedic surgery ,RD701-811 - Abstract
Category: Ankle; Arthroscopy; Basic Sciences/Biologics Introduction/Purpose: Historically, microfracture has been used to treat small talar osteochondral lesions (OLTs) with good results, while osteochondral autologous transplantation (OAT) has proven superior for the treatment of larger lesions. It is not clear which method is more effective for medium-sized lesions, around the critical size of 150 mm2 above which microfracture outcomes tend to be poor. While OAT carries the risk of co-morbidity at the knee and often requires a malleolar osteotomy, it is thought to result in superior repair tissue compared to microfracture by introducing native hyaline cartilage to the ankle. Microfracture, in contrast, results in the formation of structurally inferior fibrocartilage. The purpose of this study was to determine the relative benefits of OAT and microfracture in the treatment of medium-sized OLTs. Methods:: Patients treated for an OLT with OAT or microfracture by a single surgeon fellowship-trained in foot and ankle orthopedics between 2015 and 2018 were screened. Both OAT and microfracture techniques were augmented with a mixture of extracellular matrix and bone marrow aspirate concentrate (ECM-BMAC) for every case included in this study. Patients treated without ECM-BMAC were excluded. Only patients with a lesion size between 80 and 165 mm 2 were included. Minimum follow-up was 12 months. Clinical outcomes were collected in the form of FAOS or PROMIS scores, depending on departmental standards at the time of treatment. MRIs were collected for radiographic analysis of cartilage repair tissue. MRIs were scored using the MOCART system by a fellowship trained radiologist and were also evaluated for the presence of cysts and edema. Patient charts were reviewed to determine rates of revision surgery and therapeutic injection for pain. Results:: 52 patients were identified who fit inclusion criteria. 27 of these patients received microfracture and 25 received OAT. The average lesion size for all patients was 117.5 mm2. Patients treated with OAT had significantly higher average total MOCART scores (69 vs. 55, p = 0.04) and significantly lower rates of cyst (14% vs. 55%, p
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- 2020
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10. Minimally Invasive Robotic-Assisted Patellofemoral Arthroplasty
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Jeffrey D. Hassebrock, M.D., Justin L. Makovicka, M.D., Michael Wong, B.A., Karan A. Patel, M.D., Kelly L. Scott, M.D., David G. Deckey, M.D., and Anikar Chhabra, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Isolated patellofemoral arthritis is a common debilitating condition in adults older than 40 years of age. Surgical options such as patellofemoral arthroplasty exist for those who failed to respond to nonoperative treatment. However, early patellofemoral arthroplasty techniques often resulted in poor outcomes due to mal-tracking and malalignment of components. Robotic-assisted surgery recently has been introduced as an alternative to classic patellofemoral arthroplasty, with the potential to improve the anatomical fit and reproducibility of implant positioning. We present the technique for minimally invasive robotic-assisted patellofemoral arthroplasty system.
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- 2020
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11. Arthroscopic Evaluation of Knee Cartilage Using Optical Reflection Spectroscopy
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Justin L. Makovicka, M.D., Karan A. Patel, M.D., Jeffrey D. Hassebrock, M.D., David E. Hartigan, M.D., Michael Wong, B.A., and Anikar Chhabra, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Articular cartilage is critical for painless and low-friction range of motion; however, disruption of articular cartilage, particularly in the knee joint, is common. Treatment options are based on the size and depth of the chondral defect, as well as involvement of subchondral bone. The gold standard for evaluation of articular cartilage is with arthroscopy, but it is limited by its ability to objectively judge the depth and severity of chondral damage. Optical reflection spectroscopy has been introduced to objectively assess the thickness of cartilage. We present a technique to systematically evaluate the articular cartilage of the knee using BioOptico optical reflection spectroscopy (Arthrex) to better evaluate those with visible chondral and subchondral defects.
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- 2019
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12. Interconnections between the Oral and Gut Microbiomes: Reversal of Microbial Dysbiosis and the Balance between Systemic Health and Disease
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Brandon Khor, Michael Snow, Elisa Herrman, Nicholas Ray, Kunal Mansukhani, Karan A. Patel, Nasser Said-Al-Naief, Tom Maier, and Curtis A. Machida
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oral microbiome ,gut microbiome ,microbial dysbiosis ,inflammatory disorders ,therapeutics ,precision medicine ,Biology (General) ,QH301-705.5 - Abstract
The human microbiota represents a complex array of microbial species that influence the balance between the health and pathology of their surrounding environment. These microorganisms impart important biological benefits to their host, such as immune regulation and resistance to pathogen colonization. Dysbiosis of microbial communities in the gut and mouth precede many oral and systemic diseases such as cancer, autoimmune-related conditions, and inflammatory states, and can involve the breakdown of innate barriers, immune dysregulation, pro-inflammatory signaling, and molecular mimicry. Emerging evidence suggests that periodontitis-associated pathogens can translocate to distant sites to elicit severe local and systemic pathologies, which necessitates research into future therapies. Fecal microbiota transplantation, probiotics, prebiotics, and synbiotics represent current modes of treatment to reverse microbial dysbiosis through the introduction of health-related bacterial species and substrates. Furthermore, the emerging field of precision medicine has been shown to be an effective method in modulating host immune response through targeting molecular biomarkers and inflammatory mediators. Although connections between the human microbiome, immune system, and systemic disease are becoming more apparent, the complex interplay and future innovations in treatment modalities will become elucidated through continued research and cross-disciplinary collaboration.
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- 2021
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13. Superior Capsular Reconstruction With the Addition of an Acromial Acellular Dermal Allograft Spacer
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Justin L. Makovicka, M.D., Karan A. Patel, M.D., and John M. Tokish, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Superior capsular reconstruction has emerged as a promising technique in the treatment of massive irreparable rotator cuff tears. The technical aspects of the surgery continue to evolve, and scientific studies to evaluate these techniques are emerging. One such area of interest concerns the appropriate thickness of the graft and its role as a spacer. The original description of the graft was an autograft tensor fascia lata, which was folded to achieve a thickness of around 8 mm. It has been demonstrated that an 8-mm graft is superior biomechanically to a 4-mm graft, which exceeds the typical human dermal allograft thickness. Herein we describe a technique in which an acellular human dermal allograft was used to perform a superior capsular reconstruction and the remainder of the graft was used to resurface the undersurface of the acromion. This modification of the technique allows for arthroscopic acromial resurfacing, as well as effectively doubling the thickness of the spacer function of the graft. The technique and justification are described in detail, and this has become the senior author's standard approach to the massive irreparable rotator cuff tear in patients with Hamada stages 2 and 3.
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- 2018
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14. Medial Patellofemoral Ligament Reconstruction Using All-Soft Suture Anchors for Patellar Fixation
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Justin L. Makovicka, M.D., David E. Hartigan, M.D., Karan A. Patel, M.D., Sailesh V. Tummala, B.S., and Anikar Chhabra, M.D., M.S.
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Orthopedic surgery ,RD701-811 - Abstract
The medial patellofemoral ligament (MPFL), which is critical for both patellar stability and normal kinematics of the patellofemoral joint, is disrupted in most patellar dislocations. Consequently, MPFL reconstruction is advocated in recurrent dislocations to restore native patellar constraints. Fixation of the MPFL graft to the medial border of the patella can be achieved through various methods, each with its own benefits and drawbacks. We present a technique for MPFL fixation to the patella using all-soft suture anchors, theoretically decreasing the risk of patellar fracture and articular surface violation.
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- 2018
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15. Diagnostic Evaluation of the Knee in the Office Setting Using Small-Bore Needle Arthroscopy
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Karan A. Patel, M.D., David E. Hartigan, M.D., Justin L. Makovicka, M.D., Donald L. Dulle, III, P.A.-C., and Anikar Chhabra, M.D., M.S.
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Orthopedic surgery ,RD701-811 - Abstract
Arthroscopy is currently the gold standard for diagnosing intra-articular knee pathology. Magnetic resonance imaging (MRI) can be a clinical adjunct for diagnosis; however, it is not without its shortcomings. Although highly accurate, even advanced imaging misdiagnoses the condition in 1 in 14 patients with regard to anterior cruciate ligament pathology. Previous studies have indicated that MRI fails to identify meniscal pathology when one exists in 1 of every 10 cases, and diagnoses pathology when pathology truly does not exist in 1 of every 5 patients. In-office arthroscopy offers an alternative to formal diagnostic arthroscopy, with reduced cost and risk of complications. This is a technique article that discusses the use of small-bore needle arthroscopy in the office setting.
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- 2018
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16. Lesser Trochanter Osteoplasty for Ischiofemoral Impingement
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Jill A. Goodwin, M.D., Anikar Chhabra, M.D., Karan A. Patel, M.D., and David E. Hartigan, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Ischiofemoral impingement is a newly recognized cause of extra-articular hip pain, and is caused by contact between the lesser trochanter and ischium. Surgical intervention has been proven successful for patients with persistent pain and disability after failure of nonoperative management. This technique article provides a reliable method for endoscopic lesser trochanter osteoplasty using an anterior approach.
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- 2017
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17. Anterior Cruciate Ligament Tunnel Placement Using the Pathfinder Guide
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Karan A. Patel, M.D., Anikar Chhabra, M.D., Justin L. Makovicka, M.D., Joshua Bingham, M.D., Dana P. Piasecki, M.D., and David E. Hartigan, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Reconstruction techniques for the anterior cruciate ligament (ACL) have evolved considerably over the past 3 decades. The femoral tunnel is most commonly made via a transtibial or separate anteromedial portal approach. Benefits and drawbacks for each of these techniques exist. Improper tunnel placement is the cause of failure for ACL reconstruction 70% of the time. We present a hybrid technique for femoral tunnel placement using the Pathfinder ACL guide, which attempts to give the surgeon many of the benefits of both the transtibial and anteromedial portal techniques without the drawbacks.
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- 2017
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18. Arthroscopic Iliopsoas Release at the Level of the Lesser Trochanter Following Total Hip Arthroplasty
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Karan A. Patel, M.D., Anikar Chhabra, M.D., Jill A. Goodwin, M.D., Jaycen C. Brown, B.S., and David E. Hartigan, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Iliopsoas impingement is an uncommon cause of pain after total hip arthroplasty. If pain persists after a trial of conservative treatment, surgical intervention can alleviate the patient's symptoms. Multiple advantages exist to release the iliopsoas tendon at the level of the lesser trochanter. The purpose of this Technical Note is to demonstrate a technique for arthroscopic release of the iliopsoas tendon at the lesser trochanter after total hip arthroplasty.
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- 2017
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19. Identification of the Anterolateral Ligament on Magnetic Resonance Imaging
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Karan A. Patel, M.D., Anikar Chhabra, M.D., Jill A. Goodwin, M.D., and David E. Hartigan, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Studies continue to demonstrate the importance of the anterolateral ligament (ALL) as a secondary restraint in rotational stability of the knee. No clinical exam exists to reliably test the ALL. Advanced imaging allows the surgeon to reliably identify the ALL as an independent structure of the lateral knee. This technique paper provides a reproducible method for identification of the ALL on 3T magnetic resonance imaging based on previously conducted cadaveric dissections of the ligament.
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- 2017
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20. Hardware-Application Co-Design to Evaluate the Performance of an STDP-based Reservoir Computer.
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Hritom Das, Karan P. Patel, Shelah Ameli, Nishith N. Chakraborty, Catherine D. Schuman, and Garrett S. Rose
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- 2024
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21. Impact of Noisy Input on Evolved Spiking Neural Networks for Neuromorphic Systems.
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Karan P. Patel and Catherine D. Schuman
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- 2023
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22. Osteochondral Lesions of the Ankle and Foot
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Logan P. Haug, Andrew P. Sill, Roman Shrestha, Karan A. Patel, Todd A. Kile, and Michael G. Fox
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Radiology, Nuclear Medicine and imaging ,Orthopedics and Sports Medicine - Abstract
Osteochondral lesions (OCLs) in the ankle are more common than OCLs of the foot, but both share a similar imaging appearance. Knowledge of the various imaging modalities, as well as available surgical techniques, is important for radiologists. We discuss radiographs, ultrasonography, computed tomography, single-photon emission computed tomography/computed tomography, and magnetic resonance imaging to evaluate OCLs. In addition, various surgical techniques used to treat OCLs—debridement, retrograde drilling, microfracture, micronized cartilage-augmented microfracture, autografts, and allografts—are described with an emphasis on postoperative appearance following these techniques.
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- 2023
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23. Orthopaedic Shoulder and Elbow Fellowship Directors in the United States Have Substantial Research Output but Lack Diversity
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Jacob Smith, Muhammad Ali Elahi, M. Lane Moore, Matthew K. Doan, Jordan R. Pollock, Jeffrey D. Hassebrock, Justin L. Makovicka, Joseph C. Brinkman, and Karan A. Patel
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Rehabilitation ,Public Health, Environmental and Occupational Health ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine - Abstract
To investigate the characteristics of shoulder and elbow fellowship directors (FDs).FDs for shoulder and elbow fellowship programs in the United States were identified. Demographic, educational, and professional background data were collected from available curricula vitarum, institutional biographies, and the Scopus database. Data collected included age, sex, race/ethnicity, training locations, graduation years, advanced degrees, current institutional information, and personal research H-index.Thirty current orthopaedic shoulder and elbow FDs were identified. The mean Scopus H-index was 25.5. The mean age of FDs was 52.1 years. In total, 29 FDs (96.7%) were male and 1 (3.3%) was female. In addition, 25 of the 30 (83.3%) were White (83.3%), 4 were Asian, and 1 (3.3%) was Hispanic. Two (6.7%) had a military affiliation. Mean time from fellowship training graduation to FD appointment was 13.5 years. Mean number of years as FD was 6.1 years, whereas the number of years tenure with an FD-affiliated institution was 13.0 years. Mean calendar years for completion of orthopaedic residency training and fellowship training were 1998 and 2000, respectively. The residencies that produced the most future FDs were Hospital of the University of Pennsylvania (n = 2) and University of Nebraska Medical Center/Creighton University Health Foundation (n = 2). The fellowship that produced the most future FDs was Columbia University (n = 6). Moderate correlation was found between age and Scopus H-index (r = 0.48;Women and minorities are under-represented in leadership positions in shoulder and elbow surgery. Shoulder and elbow FDs have the highest H-index of any subspecialty reported in the orthopaedic literature. Research productivity is an important qualification when considering the characteristics of shoulder and elbow FDs.Fellowship directors can have a profound influence on current and future orthopaedic surgeons. It is important to identify the traits that characterize current fellowship directors to have a better understanding of who we choose as leaders in our field.
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- 2022
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24. Augmenting Osteochondral Autograft Transplantation and Bone Marrow Aspirate Concentrate with Particulate Cartilage Extracellular Matrix Is Associated With Improved Outcomes
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Mark C. Drakos, Oliver B. Hansen, Stephanie K. Eble, Saanchi Kukadia, Taylor N. Cabe, Prashanth Kumar, Karan A. Patel, Carolyn M. Sofka, and Jonathan T. Deland
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Cartilage, Articular ,Cartilage ,Treatment Outcome ,Intra-Articular Fractures ,Bone Marrow ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Autografts ,Magnetic Resonance Imaging ,Transplantation, Autologous ,Extracellular Matrix ,Retrospective Studies - Abstract
Background: Osteochondral autograft transplant (OAT) is often used to treat large osteochondral lesions of the talus and is generally associated with good outcomes. The addition of adjuncts such as cartilage extracellular matrix with bone marrow aspirate concentrate (ECM-BMAC) may further improve the OAT procedure but have not been thoroughly studied. We hypothesized that the placement of ECM-BMAC around the OAT graft would improve radiographic and patient-reported outcomes following OAT. Methods: Patients who received OAT, with ECM-BMAC or BMAC alone, were screened and their charts were reviewed. For patients who did receive ECM-BMAC, the mixture was spread around the edges of the OAT plug and into any surrounding areas of cartilage damage. Survey and radiographic data were collected. Average follow-up in both groups was over 2 years. Magnetic resonance imaging scans were scored using the Magnetic Resonance Observation of Cartilage Tissue (MOCART) system. Outcomes were compared statistically between groups. Results: Patients treated with ECM-BMAC (n = 34) demonstrated significantly greater improvement of scores in the FAOS categories Symptoms (17 vs −3; P = .02) and Sports Activities (40 vs 7; P = .02), and the MOCART category Subchondral Lamina ( P = .008) compared to those treated with BMAC alone (n = 30). They also experienced significantly lower rates of postoperative cysts (53% vs 18%, P = .04) and edema (94% vs 59%, P = .02). Conclusion: The addition of ECM-BMAC to OAT was associated with improved imaging and clinical outcomes compared to OAT with BMAC alone.
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- 2022
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25. Caring for Dependents Travel Awards to Promote Career Advancement of Early Career Faculty with Caregiver Responsibilities
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Miriam A. Bredella, Lauren Olson, Karan A. Patel, Anne S. Levy, Maire Leyne, and Louisa G. Sylvia
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Internal Medicine - Published
- 2023
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26. Sepsis and Total Joint Arthroplasty
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Jeffrey B. Stambough, Simon C. Mears, Barnes Cl, Benjamin M. Stronach, and Karan M Patel
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medicine.medical_specialty ,Prosthesis-Related Infections ,Joint arthroplasty ,business.industry ,Arthroplasty, Replacement, Hip ,medicine.medical_treatment ,Periprosthetic ,medicine.disease ,Prosthesis ,Intensive care unit ,law.invention ,Sepsis ,law ,Bacteremia ,Intravenous antibiotics ,medicine ,Humans ,Orthopedics and Sports Medicine ,In patient ,Arthroplasty, Replacement, Knee ,Intensive care medicine ,business - Abstract
The number of annual total joint arthroplasties (TJA) is increasing. Periprosthetic joint infections (PJI) occur when there is infection involving the prosthesis and surrounding tissue, which has the potential to develop into sepsis if left untreated. Sepsis in patients who have undergone TJA is life threatening and requires urgent treatment. If sepsis is due to PJI, the focus should be on early intravenous antibiotics with aspiration as soon as possible to diagnose the infection. Patients who develop sepsis after surgery for PJI are particularly at high risk for mortality and need to be treated in the intensive care unit.
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- 2022
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27. Abstract Number ‐ 162: Hydration Status and Functional Outcomes in Patients with Large Vessel Occlusion Stroke Undergoing Endovascular Therapy
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Abigail Baldwin‐LeClair, Avish Patel, Karan N Patel, James E Siegler, Scott Kamen, Lauren Thau, Jared Wolfe, Linda Zhang, Kavya Thomas, Nicholas Vigilante, and Jesse M Thon
- Abstract
Introduction Large vessel occlusion (LVO) and dehydration are both independently associated with poor functional outcomes and increased odds of mortality in acute ischemic stroke. Dehydration has previously been shown to affect collateral blood flow in LVO stroke, but it is unclear if this leads to worsened clinical outcomes. Methods A stroke center registry (10/2019‐12/2021) of consecutive adults who had undergone successful endovascular therapy (EVT, with thrombolysis in cerebral infarction score 2b/3) for anterior circulation LVO (ICA, M1, or M2) was queried. Dehydration on presentation was defined using laboratory surrogates: blood urea nitrogen/creatinine ratio >15 or serum osmolality >296 mOsm/kg. The primary outcome was a favorable shift in 90‐day modified Rankin Scale (mRS) using a proportional odds model, adjusting for age, pre‐stroke mRS, National Institutes of Health Stroke Scale (NIHSS), and Alberta Stroke Program Early Computed Tomography Scale (ASPECTS). Secondary outcomes included early improvement in 24h NIHSS. Results Of the 318 patients with anterior LVO who underwent EVT, 206 (65%) met criteria for dehydration, and 181 (87.9%) had both mRS and ASPECTS data available. Younger age, lower NIHSS, lower mRS, and higher ASPECTS were all strongly and independently associated with a favorable shift in 90d mRS. Dehydrated patients had similar changes in 24‐hr NIHSS scores (‐5 [interquartile range, IQR ‐10 to 0] vs. ‐5 [IQR ‐8 to 0], p = 0.37). Dehydration was not associated with a less favorable shift in 90‐day mRS (odds ratio [OR] 0.74, 95% confidence interval [CI] 0.41‐1.33), which remained non‐significant after multivariable adjustment (OR 1.46, 95%CI 0.74‐2.86). With serum osmolality assessed continuously, higher serum osm was associated with a less favorable shift in mRS at 90d (OR 0.95, 95%CI 0.92‐0.99, p = 0.009), but this did not persist after multivariable adjustment (p = 0.92) and was driven by the association between higher osmolality and age (r = 0.24, p(bonferroni)< 0.01) and pre‐stroke mRS (r = 0.20, p(bonferroni) = 0.04). Conclusions There was no association between dehydration and lower odds of early clinical improvement or long‐term functional recovery following successful endovascular thrombectomy.
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- 2023
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28. A novel multi-dimensional reliability approach for floating wind turbines under power production conditions
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Xiaosen Xu, Yihan Xing, Oleg Gaidai, Kelin Wang, Karan Sandipkumar Patel, Peng Dou, and Zhongyu Zhang
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Teknologi: 500::Marin teknologi: 580 [VDP] ,Global and Planetary Change ,vindturbiner ,Ocean Engineering ,flytende vindturbiner ,Aquatic Science ,Oceanography ,fornybar energi ,Water Science and Technology - Abstract
Floating offshore wind turbines (FOWT) generate green renewable energy and are a vital part of the modern offshore wind energy industry. Robust predicting extreme offshore loads during FOWT operations is an important safety concern. Excessive structural bending moments may occur during certain sea conditions, posing an operational risk of structural damage. This paper uses the FAST code to analyze offshore wind turbine structural loads due to environmental loads acting on a specific FOWT under actual local environmental conditions. The work proposes a unique Gaidai-Fu-Xing structural reliability approach that is probably best suited for multi-dimensional structural responses that have been simulated or measured over a long period to produce relatively large ergodic time series. In the context of numerical simulation, unlike existing reliability approaches, the novel methodology does not need to re-start simulation again each time the system fails. As shown in this work, an accurate forecast of the probability of system failure can be made using measured structural response. Furthermore, traditional reliability techniques cannot effectively deal with large dimensionality systems and cross-correction across multiple dimensions. The paper aims to establish a state-of-the-art method for extracting essential information concerning extreme responses of the FOWT through simulated time-history data. Three key components of structural loads are analyzed, including the blade-root out-of-plane bending moment, tower fore-aft bending moment, and mooring line tension. The approach suggested in this study allows predicting failure probability efficiently for a non-linear multi-dimensional dynamic system as a whole.
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- 2022
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29. Iliac Crest and Distal Radius Autografts Exhibit Distinct Cell-Intrinsic Functional Differences
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Devan D. Mehta, John F. Dankert, Daniel B. Buchalter, David J. Kirby, Karan S. Patel, Madeline Rocks, Jacques H. Hacquebord, and Philipp Leucht
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Orthopedics and Sports Medicine ,Surgery - Abstract
Autologous bone grafts demonstrate osteoconductive, osteoinductive, and osteogenic properties. Hand surgeons commonly augment surgical fixation with autografts to promote fracture healing. This study compared the intrinsic stem cell-like properties of 2 commonly used autograft sources in hand surgery: the iliac crest and distal radius.A total of 9 subjects who received an iliac crest bone graft and distal radius bone graft harvest as a part of the standard care of distal radius malunion or nonunion correction or scaphoid nonunion open reduction and internal fixation were enrolled in the study. Cells were isolated by serial collagenase digestion and subjected to fibroblast colony-forming units, osteogenesis, and adipogenesis assays. The expression levels of genes involved in osteogenesis and adipogenesis were confirmed using quantitative polymerase chain reaction.The cells isolated from the iliac crest bone graft compared with those isolated from the distal radius bone graft demonstrated significantly higher mean fibroblast colony-forming unit efficiency; increased osteogenesis, as measured using alizarin red quantification; increased adipogenesis, as measured using oil red O quantification; and higher expression levels of genes involved in osteogenesis and adipogenesis under the respective differentiation conditions.The cells isolated from the iliac crest bone graft demonstrated a higher fibroblast colony-forming unit capacity and an increased capability to undergo both osteogenesis and adipogenesis.Limited evidence exists comparing the intrinsic stem cell-like properties of the iliac crest and distal radius despite the widespread use of each source in hand and wrist surgery. The information from this investigation may assist hand and wrist surgeons with the selection of a source of autograft.
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- 2022
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30. Increasing severity of anemia is associated with poorer 30-day outcomes for total shoulder arthroplasty
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Jordan R. Pollock, John M. Tokish, Jeffrey D. Hassebrock, Karan A. Patel, M. Lane Moore, Justin L. Makovicka, and Matthew K. Doan
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medicine.medical_specialty ,Shoulder ,Multivariate analysis ,Anemia ,medicine.medical_treatment ,Osteoarthritis ,Outcomes ,Diseases of the musculoskeletal system ,Hematocrit ,Logistic regression ,Arthroplasty ,Internal medicine ,hemic and lymphatic diseases ,Medicine ,Orthopedics and Sports Medicine ,Major complication ,Orthopedic surgery ,medicine.diagnostic_test ,business.industry ,Postoperative complication ,medicine.disease ,RC925-935 ,Degenerative disease ,Surgery ,business ,RD701-811 - Abstract
Background: Total shoulder arthroplasty (TSA) has increased in utilization over the past several decades. Anemia is a common preoperative condition among patients undergoing TSA and has been associated with poorer outcomes in other surgical procedures. To the best of our knowledge, no study has analyzed the association between anemia severity and TSA outcomes. Therefore, the purpose of this study is to determine the effects that increasing severity of anemia may have on the postoperative outcomes in patients receiving primary TSA. Methods: A retrospective analysis was performed using the American College of Surgeons National Surgery Quality Improvement Project database from the years 2015 to 2018. Current Procedure Terminology code 23472 was used to identify all primary TSA procedures recorded during this time frame. Patients with greater than 38% preoperative hematocrit (HCT) were classified as having normal HCT levels. Patients with HCT values between 33% and 38% were classified as having mild anemia. All patients with less than 33% HCT were classified as having moderate/severe anemia. Patient demographic information, preoperative risk factors, and postoperative outcomes were compared among the 3 cohorts. A multivariate logistic regression including demographic factors and comorbidities was performed to determine whether increasing severity of anemia is independently associated with poorer postoperative outcomes. Results: Of the 15,185 patients included in this study, 11,404 had normal HCT levels, 2962 patients were mildly anemic, and 819 patients had moderate to severe anemia. With increasing severity of anemia, there was an increased average hospital length of stay (1.6 vs. 2.1 vs. 3.0 days, P
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- 2021
31. Comparative Accuracy of 1.5T MRI, 3T MRI, and Static Ultrasound in Diagnosis of Small Gaps in Repaired Flexor Tendons: A Cadaveric Study
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Karan A. Patel, Patricia A. Drace, Kevin J. Renfree, Nan Zhang, Nirvikar Dahiya, and Mark J. Kransdorf
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030230 surgery ,Tendons ,03 medical and health sciences ,0302 clinical medicine ,Suture (anatomy) ,Tendon Injuries ,Tensile Strength ,Cadaver ,medicine ,Humans ,Orthopedics and Sports Medicine ,Prolene ,030222 orthopedics ,Artifact (error) ,Sutures ,medicine.diagnostic_test ,Flexor tendon ,business.industry ,Suture Techniques ,Ultrasound ,Magnetic resonance imaging ,Magnetic Resonance Imaging ,Biomechanical Phenomena ,Tendon ,medicine.anatomical_structure ,Surgery ,Cadaveric spasm ,Nuclear medicine ,business - Abstract
We hypothesized that magnetic resonance imaging (MRI) would more accurately diagnose small gaps (6 mm) after flexor tendon repair than static ultrasound (US) and that suture artifact would negatively impair accuracy.A laceration of the flexor digitorum profundus was created in 160 fresh-frozen cadaveric digits and randomized to either an intact repair (0-mm gap) or repairs using a locked 4-strand suture repair with either 4-0 Prolene, Ethibond, or and gaps of 2, 4,or 6 mm; or no suture in which 2-, 4-, or 6-mm gaps were created without a suture crossing the repair site. We performed 1.5T and 3T MRI and static US studies; gap widths were estimated by radiologists blinded to suture presence and true gap widths.The 1.5 and 3.0T MRI had a lower mean error than US for gap sizes 0 and 2 mm. All 3 modalities performed similarly for 4- and 6-mm gaps. Documentation of imaging artifact worsened error, and odds of seeing artifacts were 1.72 higher with MRI than with US. Suture did not worsen artifact nor impair accuracy for any of the 3 modalities. When no suture was used, all 3 modalities significantly overestimated the true gap.MRI is most accurate for small gaps less than 4 mm. Although all modalities overestimated gap sizes in specimens with a 0-mm gap (intact tendon repair), mean overestimation (2 mm) was not clinically relevant. Ultrasound overestimated 2-mm gaps (clinically intact repairs), whereas MRIs did not. We recommend MRI for evaluation of gaps after flexor tendon repair. The 1.5T has slightly better sensitivity and specificity for distinguishing clinically intact (gap3 mm) from clinically impaired (gap3 mm) repairs than the 3T.Accurate diagnosis of intact repairs or small gaps (3 mm) might prevent unnecessary exploration or allow modification of rehabilitation protocols. Diagnosis of clinically relevant gaps (3-6 mm) may allow for earlier revision surgery before significant tendon retraction and adhesions develop, possibly necessitating a staged reconstruction.
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- 2021
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32. Bibliometric Analysis of the Top 50 Most Cited Studies on Achilles Tendon Pathology
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M. Lane Moore, Ryan J. Hawkins, Jordan R. Pollock, Justin L. Makovicka, Jack M. Haglin, Joseph C. Brinkman, and Karan A. Patel
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Orthopedics and Sports Medicine - Abstract
Background: The development of Achilles tendon treatment modalities has been rapid, and it is increasingly difficult for clinicians to stay up to date with the most influential studies in this field. In order to fully understand the current state of the literature regarding Achilles tendon injury, it is invaluable to be familiar with the foundational articles and studies upon which the field is built. Purpose: To objectively determine the 50 most frequently cited studies in Achilles tendon pathology and to conduct a bibliometric analysis. Study Design: Cross-sectional study. Methods: The Clarivate Analytics Web of Knowledge database was used to gather data and metrics of Achilles tendon research. The 50 most cited articles were selected for analysis from an initial 17,244 identified articles. The information extracted for each article included author name, publication year, country of origin, journal name, study type, and level of evidence. Results: For these 50 studies, the total number of citations was calculated to be 13,159, with a mean of 263.2 citations per paper. The most cited article collected 657 citations. The publication dates of the 50 studies included in this analysis spanned 41 years (1972-2013). The largest number of articles were published by Swedish authors (n = 14); however, many other countries were represented, including Canada and Finland (n = 6 articles each). The most prevalent study designs were cohort studies (n = 13) with level 4 evidence studies being the most common (n = 14). Conclusion: Among the 50 most influential articles in Achilles tendon pathology, the study designs most commonly used were cohort studies and review articles. Sweden was the country of origin for the most studies included on this list, which reflects this country’s interest and commitment to researching Achilles tendon injuries and treatments.
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- 2023
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33. The Effect of Patellar Surface Morphology on Subchondral Bone Alignment When Matching Patellar Osteochondral Allografts to the Central Ridge of the Patella
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Mithun Neral, Karan A. Patel, Michael Getty, Nabeel Salka, and John A. Grant
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Cartilage, Articular ,Intra-Articular Fractures ,Odonata ,Animals ,Humans ,Transplantation, Homologous ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine ,Femur ,Patella ,Allografts - Abstract
Background: Cartilage transplants in the patellofemoral joint have demonstrated lower success rates than in the femoral condyles. This is likely related to the more complex morphology and biomechanics of the joint. While previous studies have evaluated cartilage surface matching and congruence, little work has been done to study the associated subchondral bone congruency in these grafts. Purpose: To determine if differences in patellar morphology play a role in the alignment of the donor patellar osteochondral allograft subchondral bone with the native patellar subchondral bone. Study Design: Controlled laboratory study. Methods: A total of 20 (10 Wiberg I and 10 Wiberg II/III) fresh-frozen human patellae were designated as recipients and size-matched to both a Wiberg I and a Wiberg II/III patellar donor. A 16-mm osteochondral allograft transplant to the central ridge of the patella was performed in random order with each matched donor. Transplanted patellae underwent a nano—computed tomography (nano-CT) scan, were digitally reconstructed, and were superimposed on the initial nano-CT scan of the native recipient patella. MATLAB was used to determine the surface height deviation between the native and donor subchondral bone surfaces. DragonFly 3-dimensional imaging software was used to measure subchondral bone step-off heights at the native-donor interface. Differences between matched and unmatched grafts were compared using a 2-way analysis of variance and the Sidak post hoc test. Results: Subchondral bone surface deviation did not differ between Wiberg matched and unmatched allografts. The step-off height was significantly greater in unmatched (1.38 ± 0.49 mm) compared with matched (1.14 ± 0.52 mm) plugs ( P = .015). The lateral quadrant step-off differed between matched (0.89 ± 0.43 mm) and unmatched (1.60 ± 0.78 mm) grafts ( P = .007). Conclusion: While unmatched Wiberg patellar osteochondral allograft implantation did not result in significantly different subchondral bone surface height deviations, there was a significant difference in the circumferential subchondral bone step-off height in the lateral quadrant. Further investigation using finite element analysis modeling will help determine the role of subchondral bone surface on shear and compression force distributions in these areas. Clinical Relevance: Given that subchondral bone stiffness and morphology play a role in cartilage health, subchondral bone congruency may play a role in graft survival. Understanding how this congruency plays a role in cartilage force distribution will help surgeons improve the long-term success of osteochondral allograft transplants.
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- 2022
34. Promoting Women in Academic Medicine during COVID-19 and Beyond
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Karan A Patel, Miriam A. Bredella, Anne S Levy, Cristina R. Ferrone, Bakhos A. Tannous, and Mary L. Bouxsein
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medicine.medical_specialty ,Gender equity ,2019-20 coronavirus outbreak ,Faculty, Medical ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,media_common.quotation_subject ,gender equity ,Faculty medical ,diversity ,Physicians, Women ,Internal Medicine ,medicine ,Humans ,Academic medicine ,media_common ,Academic Medical Centers ,SARS-CoV-2 ,virtual lecture ,business.industry ,COVID-19 ,Family medicine ,Female ,business ,Concise Research Report ,Diversity (politics) - Published
- 2021
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35. Comparison of Two-level Cervical Disc Replacement Versus Two-level Anterior Cervical Discectomy and Fusion in the Outpatient Setting
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Justin L. Makovicka, Jeffrey D. Hassebrock, Matthew K. Doan, Karan A. Patel, Andrew S. Chung, and Thomas M Polveroni
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Cervical disc replacement ,030222 orthopedics ,medicine.medical_specialty ,business.industry ,Postoperative complication ,chemical and pharmacologic phenomena ,Retrospective cohort study ,Anterior cervical discectomy and fusion ,Readmission rate ,03 medical and health sciences ,0302 clinical medicine ,Multicenter study ,Internal medicine ,mental disorders ,medicine ,Outpatient setting ,Orthopedics and Sports Medicine ,Neurology (clinical) ,business ,030217 neurology & neurosurgery ,American society of anesthesiologists - Abstract
STUDY DESIGN Retrospective cohort study. OBJECTIVE The aim of this study was to evaluate the safety of two-level cervical disc replacement (CDR) in the outpatient setting. SUMMARY OF BACKGROUND DATA Despite growing interest in CDR, limited data exist evaluating the safety of two-level CDR in the outpatient setting. METHODS The National Surgical Quality Improvement Program (NSQIP) database was queried for all two-level anterior cervical discectomy and fusion (ACDF) and CDR procedures between 2015 and 2018. Demographics, comorbidities, and 30-day postoperative complication rates of outpatient two-level CDR were compared to those of inpatient two-level CDR and outpatient two-level ACDF. Radiographic data are not available in the NSQIP. RESULTS A total of 403 outpatient CDRs were compared to 408 inpatient CDRs and 4134 outpatient ACDFs. Outpatient CDR patients were older and more likely to have pulmonary comorbidities compared to inpatient CDR (P
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- 2020
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36. Navicular Stress Fractures
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Zachary K. Christopher, Mark C. Drakos, Karan A Patel, and Martin J. O’Malley
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030222 orthopedics ,medicine.medical_specialty ,Stress fractures ,Fractures, Stress ,business.industry ,medicine.medical_treatment ,Nonunion ,Tarsal Bones ,030229 sport sciences ,medicine.disease ,Surgery ,Fracture Fixation, Internal ,03 medical and health sciences ,0302 clinical medicine ,Athletes ,Fracture fixation ,medicine ,Delayed union ,Humans ,Internal fixation ,Orthopedics and Sports Medicine ,Blood supply ,business ,Reduction (orthopedic surgery) - Abstract
Navicular stress fractures are multifactorial injuries due to chronic overload on the navicular, particularly in young athletes. The navicular is subject to unique stresses and has a complex blood supply, making it susceptible to stress fractures and potentially delayed union or nonunion. Expeditious diagnosis is critical to prevent a delay in treatment and a poor outcome. Advanced imaging is essential in making the diagnosis and monitoring healing. Both nonsurgical and surgical treatments have demonstrated good results. Nonsurgical management consists of a period of immobilization and nonweight bearing, and surgical management typically involves open reduction and internal fixation. Patients need to be appropriately counseled regarding expectations for these challenging injuries.
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- 2020
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37. Management of Achilles Tendon Injuries in the Elite Athlete
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Karan A. Patel and Martin J. O’Malley
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030222 orthopedics ,Achilles tendon ,medicine.medical_specialty ,business.industry ,030229 sport sciences ,Achilles Tendon ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Athletes ,Tendon Injuries ,Elite ,medicine ,Physical therapy ,Humans ,Orthopedic Procedures ,Orthopedics and Sports Medicine ,Elite athletes ,Achilles tendon rupture ,medicine.symptom ,business - Abstract
The management of Achilles tendon rupture continues to be controversial in the everyday athlete; however, there is strong evidence indicating that surgical intervention is preferred in elite athletes due to the return of greater strength and peak torque. We review the published literature, as well as our operative technique and post-operative protocol in the management of Achilles tendon injuries in elite athletes.
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- 2020
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38. Neck and Cervical Spine Injuries in National College Athletic Association Athletes
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David G. Deckey, Jeffrey D. Hassebrock, Anikar Chhabra, Walker L. Asprey, Andrew S. Chung, Sailesh V. Tummala, Austin Pena, Justin L. Makovicka, and Karan A. Patel
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Male ,medicine.medical_specialty ,Field hockey ,Databases, Factual ,Universities ,medicine.medical_treatment ,Football ,Neck Injuries ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Soccer ,Epidemiology ,Injury prevention ,medicine ,Humans ,Orthopedics and Sports Medicine ,Young adult ,Students ,030222 orthopedics ,Rehabilitation ,biology ,business.industry ,Athletes ,Incidence ,Incidence (epidemiology) ,biology.organism_classification ,United States ,Epidemiologic Studies ,Hockey ,Athletic Injuries ,Etiology ,Physical therapy ,Female ,Neurology (clinical) ,business ,human activities ,030217 neurology & neurosurgery - Abstract
Study design Descriptive epidemiology study. Objective The purpose of this study was to describe the epidemiology of neck and cervical spine injuries in collegiate athletes over a 5-year period. Summary of background data The incidence and etiology of neck and cervical spine injuries in National Collegiate Athletic Association (NCAA) athletes has not been well defined in recent years. Methods The incidence and characteristics of neck and cervical spine injuries were identified utilizing the NCAA Injury Surveillance Program database. Rates of injury were calculated as the number of injuries divided by the total number of athlete-exposures (AEs). AEs were defined as any student participation in one NCAA-sanctioned practice or competition. Results Nationally, there were an estimated 11,510 neck and cervical spine injuries over the 5-year period. These occurred at a rate of 7.05 per 100,000 athlete-exposures (AEs). The rate of neck and cervical spine injuries in men was 2.66 per 100,000 AEs, while women suffered injuries at a rate of 1.95 per 100,000 AEs. In sex-comparable sports, men were 1.36 times more likely to suffer a neck or cervical spine injury compared with women. Men's football (29.09 per 100,000 AEs) and women's field hockey (11.51 per 100,000 AEs) were the sports with the highest rates of injuries. These injuries were 3.94 times more likely to occur during competition compared with practice. In-season injury rates were the highest, at 8.18 per 100,000 AEs. Conclusion The vast majority of neck and cervical spine injuries in NCAA athletes are minor and uncommon. Across all sports in both sexes, the majority of injuries were new, and occurred during in-season competitions. Most athletes returned to play within 24 hours of injury. These data can inform players, parents, coaches, athletic trainers, and physicians regarding the prevalence and rates of these injuries and potentially inform decision-making regarding injury prevention, treatment, and rehabilitation. Level of evidence 4.
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- 2020
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39. Investigation of Fellowship Leadership in Orthopaedic Musculoskeletal Oncology
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M. Lane Moore, Muhammad Ali Elahi, Matthew K. Doan, Jordan R. Pollock, Justin L. Makovicka, Jeffrey D. Hassebrock, Joseph C. Brinkman, and Karan A. Patel
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Adult ,Male ,Leadership ,Orthopedics ,Bibliometrics ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Female ,Efficiency ,Fellowships and Scholarships ,Middle Aged - Abstract
The purpose of this study was to determine the objective characteristics of orthopaedic musculoskeletal oncology fellowship directors (FDs) by concentrating on the demographics, academic background, institutional history, research experience, and professional affiliations of these leaders.Data were collected for each FD through institutional biographies or publicly available curriculum vitae. The data collected for each FD included demographic, professional, and research information.Of the 19 FDs, 15 (78.9%) were male, and 4 (21.1%) were female. The mean age for all FDs was 49.2 ± 9.1 years. Most FDs were White (n = 16; 84.2%). The mean Scopus H-index, total number of citations, and total number of publications among all 19 FDs were 21.6 ± 13.8, 2,290.6 ± 2,709.0, and 84.0 ± 54.7, respectively. The mean number of years serving in the FD role was 7.1 ± 9.1 years, and the mean number of years that the FD was employed at his/her current institution was 11.1 ± 8.1 years.This study shows that orthopaedic musculoskeletal oncology FDs were mainly White (84.2%), male (78.9%), and in their late 40s; have filled their role as FD for an average of 7.1 years; and are very productive in research.
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- 2022
40. Exploring the binding of mitoxantrone to DNA using optical tweezers
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Karan R. Patel and Thayaparan Paramanathan
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Biophysics - Published
- 2023
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41. Open Achilles Tendon Repair
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M. Lane Moore, Jordan R. Pollock, Phillip J. Karsen, Jack M. Haglin, Cara H. Lai, Muhammad A. Elahi, Anikar Chhabra, Martin J. O’Malley, and Karan A. Patel
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Orthopedics and Sports Medicine ,Surgery - Published
- 2023
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42. Top-100 Most-Cited Sports-Related Concussion Articles Focus on Symptomatology, Epidemiology, and Demographics
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Karan A. Patel, Anikar Chhabra, Jordan R. Pollock, Jeffrey D. Hassebrock, M. Lane Moore, and Kade S. McQuivey
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medicine.medical_specialty ,business.industry ,Rehabilitation ,Public Health, Environmental and Occupational Health ,Physical Therapy, Sports Therapy and Rehabilitation ,Evidence-based medicine ,medicine.disease ,Country of origin ,Analytics ,Family medicine ,Epidemiology ,Concussion ,Sports medicine ,medicine ,Relevance (law) ,Original Article ,Orthopedics and Sports Medicine ,Psychology ,Citation ,business ,RC1200-1245 ,Cohort study - Abstract
Purpose To analyze the top-100 cited articles on sports-related concussions together with a bibliometric analysis to determine citations by year, level of evidence, study design, and several other factors related to the top referenced articles in sports concussions. Methods The Clarivate Analytics Web of Knowledge database was used to gather data using Boolean queries to capture all possible iterations of sports-related concussion research. Articles were organized in descending order based on the number of citations and included or excluded based on relevance to concussion. Collected information included author name, publication year, country of origin, journal name, article type, study focus, and the level of evidence. Results The top-100 articles were cited 31,197 times with an average of 312.0 citations per publication. More than one half were published in 2006 or later (52). Cohort studies and descriptive articles were the most prevalent study types (22 each). Studies with Level V evidence were the most common (33). The most common areas of study were symptomatology (short term, long term) with 17 articles, followed by epidemiology/demographics with 16 articles. The least common area of study was concussion prevention (2 articles), followed by management/treatment, diagnostics (labs, imaging) with 4 articles each. Conclusions We identified the most influential studies in sports-related concussion based on number of citations and citation density. A majority of these articles were published in the United States after 2006 and are most commonly cohort studies (Level IV evidence) and descriptive articles (Level V evidence). Current research focuses most heavily on the symptomatology and epidemiology/demographics of sports concussion. Clinical Relevance This study serves to identify the most influential articles in sports-related concussion and identify research topics with general deficiencies within the field of sports-related concussion research.
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- 2021
43. Prevalence of Cannabinoid (CBD) Use in Orthopaedic Sports Medicine Patients
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David G. Deckey, Matthew Doan, Jeffrey D. Hassebrock, Karan A. Patel, Kostas Economopoulos, John M. Tokish, Joshua S. Bingham, and Anikar Chhabra
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Orthopedics and Sports Medicine - Abstract
Background: Although there is some evidence that cannabinoid (CBD) products may provide a therapeutic effect for musculoskeletal pain, little is known about the usage patterns or their prevalence of use in orthopaedic sports medicine patients. Purpose: To report the prevalence and perceived self-efficacy of CBD products in patients evaluated in an orthopaedic sports medicine clinic. Study Design: Descriptive epidemiology study. Level of evidence, 2. Methods: The study population consisted of new patients who visited an orthopaedic surgery sports medicine clinic at a large academic center for consultation with a surgeon between August 2020 and March 2021. All patients were asked to complete a survey that assessed perceived pain and effectiveness of CBD products and other nonsurgical treatment modalities using the Single Assessment Numeric Evaluation score (range, 0-100) and the Numeric Pain Rating Scale (NRS). Descriptive factors were collected via chart review. Descriptive statistics were used to characterize the data. Results: Overall, 823 patients completed the survey (45.4% female; mean age, 51 years [range, 18-87 years]; mean body mass index, 28.9 [range, 17.2-58.4]). Body areas involved included 285 shoulders, 44 elbows, 76 hips, 276 knees, 58 ankles, and 77 other. Of these patients, 19% (152/823) endorsed the use of CBD products before their initial evaluation. The mean NRS for pain was significantly different between non-CBD users and CBD users (5.6 vs 6.1; P = .029). CBD users were significantly more likely to have tried other nonoperative modalities compared with nonusers, including nonsteroidal anti-inflammatory drugs (79.6% vs 69.8%; P = .032), bracing (44.7% vs 34.6%; P = .024), steroid injections (38.8% vs 21.6%; P < .001), and physical therapy (54% vs 36.1%; P < .001). In addition, 30.9% of CBD utilizers reported marijuana use compared with 2.8% of non-CBD users ( P < .001) for management of their pain. Conclusion: In the current study, 19% of patients had used CBD products to manage joint-related issues. Sports medicine providers should be aware of this high incidence of usage and the potential interactions CBD products may have with other treatment modalities. Further studies are needed to assess the effectiveness of CBD as a therapeutic agent and the specific interactions it has with other drugs and other forms of treatment.
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- 2021
44. Preoperative Intra-articular Steroid Injections as Predictors of Hip Arthroscopy: 2-Year Outcomes
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Tala Mujahed, Justin L. Makovicka, Kostas J. Economopoulos, Jeffrey D. Hassebrock, Jordan R. Pollock, Justin G. Wilcox, and Karan A. Patel
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musculoskeletal diseases ,medicine.medical_specialty ,business.industry ,intra-articular steroid injection ,medicine.disease ,Article ,Surgery ,Intra articular ,hip arthroscopy ,medicine ,positive predictor ,Orthopedics and Sports Medicine ,In patient ,Hip arthroscopy ,business ,Femoroacetabular impingement - Abstract
Background:In patients with femoroacetabular impingement, preoperative diagnostic injections are commonly used to establish a diagnosis of intra-articular pathology. In some cases, intra-articular steroid injections are also used for therapeutic purposes.Purpose/Hypothesis:The purpose of this study was to determine if a positive response to intra-articular steroid injection was predictive of superior outcomes after hip arthroscopy to determine if the response to intra-articular steroid injection was predictive of outcomes after hip arthroscopy. It was hypothesized that a positive response to a preoperative hip injection would be predictive of improved short- to midterm outcomes after hip arthroscopy.Study Design:Cohort study; Level of evidence, 3.Methods:This was a retrospective study of 208 patients who elected to have ultrasound-guided intra-articular steroid injection before they underwent hip arthroscopy between January 2016 and December 2016. Patients were divided into 2 groups: those who showed improvement in pain after the injection (steroid responder group) and those who showed no response (nonresponder group). The authors compared the preoperative and 2-year postoperative patient-reported outcomes (modified Harris Hip Score [mHHS] and Hip Outcome Score–Activities of Daily Living [HOS-ADL]) and radiographic findings between groups. Clinical endpoints, including rates of revision and conversion to total hip arthroplasty, were also reviewed.Results:There were 88 patients in the nonresponder group and 120 patients in the responder group, with no significant between-group differences in preoperative descriptive variables. The responder group had significantly higher 2-year mHHS and HOS-ADL, pre- to postoperative change in mHHS and HOS-ADL, percentage of patients achieving the patient acceptable symptomatic state (PASS) on the mHHS, and percentage of patients reaching the minimum clinically important difference and the PASS on the HOS-ADL. There was no difference in Tönnis grade, acetabular labrum articular disruption grade, revision rate, or conversion to total hip arthroplasty between the 2 groups.Conclusion:The response to preoperative intra-articular injection did aid in predicting 2-year patient-reported outcomes of hip arthroscopy for femoroacetabular impingement. Overall, the result of a preoperative intra-articular injection can be a helpful clinical tool for surgical decision-making and counseling patients on expected outcomes after hip arthroscopy.
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- 2021
45. Intradural lumbar disc herniation: illustrative case
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Karan S. Patel, Yixuan Tong, Rivka C. Ihejirika, and Themistocles S. Protopsaltis
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Lumbar ,business.industry ,Medicine ,General Medicine ,Lumbar disc herniation ,Anatomy ,business - Abstract
BACKGROUND Accounting for less than 0.4% of disc herniations, intradural lumbar disc herniations (ILDHs) are a rare occurrence primarily described as a complication after lumbar spine surgery. It is speculated that the herniation may propagate intradurally from either an unrecognized dural defect after initial surgery or as a result of adhesions between the dura and posterior longitudinal ligament. This report explores the etiology, presentation, diagnostic evaluation, and treatment of ILDH along with a case report and microsurgery video. OBSERVATIONS A 67-year-old patient who 1 year earlier had undergone an L2–5 laminectomy and L2–3 decompression with no known complications presented with low back pain and radiating right leg, buttock, and groin pain for 1 month. Physical examination indicated no numbness or weakness. Magnetic resonance imaging demonstrated a large ILDH. A transforaminal interbody fusion was performed followed by a durotomy, ILDH removal, and dural closure. A ventral dural defect was found and repaired during the procedure. LESSONS The treatment for ILDH is laminectomy with dorsal durotomy. Because ILDH has rarely been described in literature, understanding its presentation is crucial for prompt identification and management.
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- 2021
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46. Publicly Available Pricing Information for Orthopaedic Upper Extremity Procedures in the United States Lacks Transparency and Consistency Between Major Hospitals
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M. Lane Moore, Jordan R. Pollock, Matthew K. Doan, Jack M. Haglin, Kelly L. Scott, Joshua S. Bingham, and Karan A. Patel
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Rehabilitation ,Public Health, Environmental and Occupational Health ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine - Abstract
The purpose of this study was to assess the price variation of various Medicare severity diagnosis-related group codes for orthopaedic upper extremity procedures for the top 20 orthopaedic hospitals using chargemaster price listings from each hospital.The top 20 orthopaedic hospitals in the United States were determined by querying theOf the top 20 orthopaedic hospitals, 18 had publicly available pricing information in DRG format on their websites. The DRG code with the highest pricing variability was Hand Injury Procedures (DRG 906; range, $12,832-$253,633). The procedure with the least pricing variability was Hand or Wrist Procedures (DRG 514; range, $24,533-$128,403). Additionally, only the cost of living index was a statistically significant predictor of procedure pricing with a weak correlation.Hospital chargemaster listings are lacking in 2 major areas: true price transparency and standardization/consistency between hospitals. Chargemaster data are often difficult to find, confusing to patients, and inaccurate. Additionally, the price range for a single DRG code can also vary substantially depending on the hospital. It is possible that hospitals located in areas with high costs of living and median incomes would charge higher prices, but these factors were not found to support this hypothesis.
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- 2021
47. The Effect of Patellar Surface Morphology On Subchondral Bone Alignment When Matching Patellar Osteochondral Allografts (206)
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Mithun Neral, Nabeel Salka, Karan A. Patel, John Grant, and Michael Getty
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Morphology (linguistics) ,Subchondral bone ,business.industry ,Medicine ,Orthopedics and Sports Medicine ,Patellar surface ,business ,Article ,Biomedical engineering - Abstract
Objectives: Recent research has shown that implanting a patellar osteochondral allograft with a non-matched surface morphology (i.e., Wiberg classification) does not create increased chondral surface deviation or circumferential step-off in the donor plug compared to the native patella. While much of the research on patellar osteochondral allografts has been focused on chondral surface matching, little has been done to determine if the subchondral bone alignment at the donor:native interface plays a role in graft healing, local force distribution, and long term success of the allograft transplant. Previous work in our lab demonstrated that even when the patellar cartilage surface was well matched, notable differences in subchondral bone alignment were observed. The purpose of this study was therefore to use surface contour mapping of subchondral bone to determine if differences in Wiberg classification play a role in the ability of donor patellar osteochondral allograft subchondral bone to align with the native patellar subchondral bone when treating osteochondral defects of the patellar apex. The hypothesis was that patellar surface morphology would have an effect on subchondral bone surface height deviation and circumferential step-off when performing osteochondral allograft transplants of the patellar apex. Methods: Sixty fresh frozen human patellae were acquired from a national donor procurement company. Twenty (10 Wiberg I and 10 Wiberg II/III) patellae were designated as the recipient and then nano-CT scanned. Each recipient was size-matched (within ±2mm tibial width) to both a Wiberg I and a Wiberg II/III patellar donor. A 16mm circular osteochondral “defect” centered on the central ridge of the patella was then created in the recipient patella. A randomly-ordered donor Wiberg I or Wiberg II/III plug was harvested from a homologous location and transplanted into the recipient. The recipient was then nano-CT scanner, digitally reconstructed, and superimposed on the initial nano-CT scan of the native recipient patella. After careful atraumatic removal of the first donor plug, the process was repeated using the other allograft plug. MATLAB was used to determine the root mean square (RMS) surface height deviation between the native and donor subchondral bone surfaces. Dragonfly 3D imaging software was used to measure the RMS subchondral bone step-off height at 3° increments around the circumference of the graft. Surface height deviation and circumferential step-off height were analyzed for the whole surface and by quadrant to determine if there were local differences. ANOVA was used to compare surface deviation and step-off heights between matched and unmatched grafts. Sidak’s multiple comparison test was used to complete sub-analysis between patellar graft quadrants. Comparisons were made between matched and unmatched grafts in terms of the RMS surface height deviation and step-off, as well as in the percentage of measurements that were more than 0.5mm, 1mm, and 2mm proud or sunken relative to the native surface. Results: There were no significant differences in RMS subchondral bone surface height deviation between matched and unmatched Wiberg plugs as a whole or by quadrant (RMS range = 0.69 to 0.97mm, p = 0.45 – 1.0). There was a significant difference in RMS circumferential step-off height between matched (1.14 ± 0.52mm) and unmatched (1.38 ± 0.49mm) Wiberg plugs ( p=0.015). The majority of these increased step-off measurements occurred in the lateral quadrant with lateral quadrant RMS step-off of 0.89 ± 0.43mm in matched grafts and 1.60 ± 0.78mm in unmatched grafts ( p=0.007). There was also a significant difference in the percent of step-off measurements greater than 2mm sunken in the lateral quadrant between matched and unmatched grafts (5.17 ± 20.87% matched, 24.5 ± 36.39% unmatched, p=0.028). There were no significant differences between matched and unmatched grafts for any other comparison using 0.5, 1, or 2mm cut-offs for circumferential step-off or surface height deviation. Combining all allografts, the respective proportion of surface deviation and circumferential step-off height measurements that were above the stated thresholds were as follows: 31% and 34% for a 0.5mm threshold, 15% and 21% for a 1mm threshold, and 2% and 8% for a 2mm threshold. Conclusions: While unmatched Wiberg patella osteochondral allograft implantation did not result in significantly different subchondral bone surface height deviations, there were significant differences in circumferential subchondral bone step-off heights. The majority of step-off height differences between Wiberg matched and unmatched osteochondral allografts occurred in the lateral quadrant. In comparison to previous data evaluating differences in the cartilage surface match in these patellar OCA transplants, the deviations and step-off heights in the subchondral bone identified in the current study were approximately 0.5mm greater than the differences in the cartilage surface. These findings therefore suggest there is greater variability in the alignment of the subchondral bone in these patellar osteochondral allografts than there is in the cartilage surface. Further investigation using finite element analysis modeling will help determine the implications of subchondral bone surface deviation and circumferential step-off on local cartilage:bone compression and shear force distribution. These studies may shed light on the mechanisms of failure in patellar osteochondral transplants and may help to better understand the contribution of subchondral bone alignment in OCA healing and long-term outcome.
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- 2021
48. Talus Visualization in Ankle Fractures: How Much Are We Really Seeing?
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Nathaniel B. Hinckley, Jeffrey D. Hassebrock, Phillip J. Karsen, David G. Deckey, Andrea Fernandez, Todd A. Kile, Mark C. Drakos, and Karan A. Patel
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chondral injury ,ankle arthritis ,ankle arthroscopy ,posttraumatic arthritis ,Orthopedics and Sports Medicine ,talus ,ankle fracture ,Article - Abstract
Background: Despite appropriate care, a subset of patients with ankle fractures has persistent pain. This condition may be associated with intra-articular pathology, which is present up to 65% of the time. Purpose: To quantify how much of the talus is visible through an open approach to a standard supination external rotation bimalleolar ankle fracture as a percentage of the entire weightbearing surface of the talus. Study Design: Descriptive laboratory study. Methods: Standard ankle approaches to lateral and medial malleolar fractures were performed in 4 cadaveric ankles from 2 cadavers. Osteotomies were made to simulate a supination external rotation bimalleolar ankle fracture based on the Lauge-Hansen classification. The visible segments of talar cartilage were removed. The tali were then exhumed, and the entire weightbearing superior portion of the talus was assessed and compared with the amount of cartilage removed by an open approach. The mean of the data points as well as the 95% confidence interval were calculated. Results: Four ankle specimens from 2 cadavers were used for these measurements. The mean surface area of the talus was 14.0 cm2 (95% CI, 13.3-14.7 cm2), while the mean area visible via an open approach was 2.1 cm2 (95% CI, 0.5-3.6 cm2). The mean proportion of the talus visualized via an open approach was 14.8% (95% CI, 3.6-26.1%). Conclusion: These findings indicate that the true area of weightbearing talar surface visible during an open exposure may be less than what many surgeons postulate. Clinical Relevance: Only a small fracture of the talus is visible via an open approach to the talus during fracture fixation. This could warrant arthroscopic evaluation of these injuries to evaluate and treat osteocondral lesions resulting from ankle fractures.
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- 2021
49. Between 2000 and 2020, Reimbursement for Orthopaedic Foot and Ankle Surgery Decreased by 30
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Jordan R. Pollock, M. Lane Moore, Jack M. Haglin, Matthew P. LeBlanc, Christian S. Rosenow, Justin L. Makovicka, David G. Deckey, Jeffrey D. Hassebrock, Joshua S. Bingham, and Karan A. Patel
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Rehabilitation ,Public Health, Environmental and Occupational Health ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine - Abstract
To examine and analyze Medicare reimbursement rates from 2000 to 2020 for orthopaedic foot and ankle procedures.The 20 most used orthopaedic foot and ankle surgical procedures were gathered from the Centers for MedicareMedicaid Services website using the Medicare Provider Utilization and Payment Data Public Use File 2017. The reimbursement data for each code were gathered from The Physician Fee Schedule Look-Up Tool from Centers for MedicareMedicaid Services. The reimbursement values were adjusted for inflation to 2020 U.S. dollars using the consumer price index.The average inflation-adjusted reimbursement for included procedures decreased by 30% from 2000 to 2020. The greatest mean decreases were observed for "correction of hallux valgus" (-47%) and "partial excision of foot bone" (-41%). The procedures with the smallest mean decreases were observed in "treatment of "Amputation of toe" (-19%) and "closed treatment of metatarsal fracture" (-7%).From 2000 to 2020, Inflation-adjusted Medicare reimbursement for foot and ankle surgery decreased by 30%.IV; economic analysis.
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- 2021
50. Lateral Ligament Reconstruction With Hamstring Graft for Ankle Instability: Outcomes for Primary and Revision Cases
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Stephanie K. Eble, Karan A. Patel, Mark C. Drakos, and Oliver B. Hansen
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Adult ,Joint Instability ,medicine.medical_specialty ,Physical Therapy, Sports Therapy and Rehabilitation ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Orthopedics and Sports Medicine ,Ankle instability ,030222 orthopedics ,business.industry ,Optimal treatment ,030229 sport sciences ,Surgery ,Ankle stabilization ,medicine.anatomical_structure ,Ligament ,Quality of Life ,Female ,Ankle ,business ,Lateral Ligament, Ankle ,Hamstring ,Ankle Joint - Abstract
Background: Optimal treatment for patients with severe ankle instability or failed previous ankle stabilization is not well defined, and newer techniques have limited presence in the literature. Purpose/Hypothesis: The purpose of this study was to evaluate clinical and radiographic outcomes after modified anatomic lateral ligament reconstruction using hamstring auto- or allograft in primary cases versus revision cases. We hypothesized that patients undergoing a revision procedure would demonstrate inferior patient-reported and radiographic outcomes. Study Design: Cohort study; Level of evidence, 3. Methods: Patients who underwent modified anatomic lateral ligament reconstruction by a single surgeon between 2010 and 2017 were identified. Indications included failure of previous ankle stabilization or severe ankle laxity. Patients completed preoperative and minimum 1-year postoperative Foot and Ankle Outcome Score (FAOS) surveys. They also underwent pre- and postoperative stress radiographs using the Telos Stress Device. Results: A total of 41 patients (42 ankles) were identified. The mean age was 32.1 years, and 36 patients (88%) were women. There were 25 primary procedures and 17 revision procedures. Hamstring autograft was utilized in 35 ankles and hamstring allograft in 7 ankles. A total of 34 patients (83%) provided postoperative patient-reported outcome scores at a mean of 26 months (range, 12-65 months). When comparing primary versus revision procedures, revision patients had significantly lower FAOS Pain (77.14 vs 90.66; P = .009), Sports (63.46 vs 82.16; P = .008), and Quality of Life (53.53 vs 76.70; P = .002) scores. In total, 34 patients (83%) had stress radiographs at a mean of 14 months (range, 3-62 months) postoperatively. Revision patients also had lower, though statistically insignificant, postoperative talar tilt measurements on average (5.73° vs 7.10°; P = .252), and pre- to postoperative change in talar tilt was not significantly different between groups (−4.94° vs −7.03°; P = .415). Conclusion: Revision procedures had significantly lower postoperative patient-reported outcome scores and lower talar tilt compared with patients undergoing a primary procedure, although the pre- to postoperative change in the talar tilt was not significantly different between groups.
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- 2021
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