1. An Italian multicentre experience in endoscopic endonasal treatment of congenital choanal atresia: Proposal for a novel classification system of surgical outcomes
- Author
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Apostolos Karligkiotis, Paolo Castelnuovo, Stefania Gallo, Alessandro Pusateri, Paolo Farneti, Vittorio Sciarretta, Fabio Pagella, Ernesto Pasquini, Francesco Zappoli-Thyrion, Karligkiotis, Apostolo, Farneti, Paolo, Gallo, Stefania, Pusateri, Alessandro, Zappoli-Thyrion, Francesco, Sciarretta, Vittorio, Pagella, Fabio, Castelnuovo, Paolo, and Pasquini, Ernesto
- Subjects
Male ,Mucosal flaps ,Endoscopic endonasal surgery ,Choanal atresia ,Mucosal flap ,CHARGE syndrome ,0302 clinical medicine ,Mitomycin C ,Child ,030223 otorhinolaryngology ,Congenital malformations ,medicine.diagnostic_test ,Otorhinolaryngology2734 Pathology and Forensic Medicine ,Middle Aged ,Treatment Outcome ,Italy ,Child, Preschool ,Female ,Nasal Cavity ,Oral Surgery ,Adult ,Reoperation ,medicine.medical_specialty ,Adolescent ,Choanal Atresia ,03 medical and health sciences ,medicine ,Humans ,Risk factor ,Aged ,Retrospective Studies ,Nasal stents ,Surgery ,business.industry ,Infant, Newborn ,Infant ,Endoscopy ,Retrospective cohort study ,medicine.disease ,Stenosis ,Otorhinolaryngology ,Atresia ,Congenital malformation ,business ,030217 neurology & neurosurgery - Abstract
Objective The purposes of this study were to report our experience with endoscopic treatment of choanal atresia (CA), to illustrate our surgical technique and analyse the different factors that may affect outcomes. Material and methods A retrospective review was performed of patients affected by congenital CA and treated between June 1996 and November 2013 at three referral centres which follow a uniform policy. Results Eighty-four patients with CA (55 unilateral and 29 bilateral), aged between one day and 76 years (mean, 13 years) were included. Associated malformations were present in 28 patients. The overall success rate was 93%, with 96.3% and 86.2% success rates for unilateral and bilateral CA respectively. Six patients (7%) required revision surgery for early symptomatic restenosis. Statistical analysis revealed that outcomes were not influenced by sex, previous surgeries, unilateral versus bilateral atresia or associated anomalies. However, age seemed to be a prognostic risk factor for patients under one year-old. Conclusion The endoscopic endonasal approach is safe and effective, with a very high success rate and low morbidity. The removal of the vomer and the use of mucoperiosteal flaps are the main keys to avoiding postoperative stenosis. The use of stents or Mitomycin C is therefore not mandatory.
- Published
- 2017