42 results on '"Karnell MP"'
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2. Comparison of resonance outcomes after pharyngeal flap and Furlow double-opposing Z-plasty for surgical management of velopharyngeal incompetence.
- Author
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Dailey SA, Karnell MP, Karnell LH, and Canady JW
- Abstract
OBJECTIVE: The purpose of this study was to test the hypothesis that no significant difference exists in the speech outcomes between patients with severe velopharyngeal incompetence (VPI) who receive a pharyngeal flap and patients with less severe VPI who receive a Z-plasty for management of VPI. DESIGN: This retrospective study from 1993 to 2002 included a review of pre- and postoperative perceptual speech and resonance assessments of patients with marginal VPI who received a Furlow double-opposing Z-plasty and patients with VPI who received a pharyngeal flap. SETTING: All patients had surgical management of VPI at the Cleft Palate-Craniofacial Clinic at University of Iowa Hospitals and Clinics. RESULTS: Both groups benefited from surgery with significant reduction in perceived hypernasality (p < .001). Comparison of postoperative assessments indicated no difference between the groups in hypernasality or hyponasality ratings. Neither group had a significant increase in hyponasality. CONCLUSION: Both pharyngeal flap and double-opposing Z-plasty proved equally effective at reducing hypernasality when the selection of the surgical procedures was based on preoperative ratings of perceived hypernasality and evaluation of velopharyngeal physiology. Severity of the VPI is an important factor when considering surgical management of VPI. Thorough preoperative evaluations of patients with VPI are essential in appropriate treatment planning. [ABSTRACT FROM AUTHOR]
- Published
- 2006
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3. Long-term follow-up of fat injection laryngoplasty for unilateral vocal cord paralysis.
- Author
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McCulloch TM, Andrews BT, Hoffman HT, Graham SM, Karnell MP, and Minnick C
- Published
- 2002
4. Arytenoid adduction combined with Gore-Tex medialization thyroplasty.
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McCulloch TM, Hoffman HT, Andrews BT, and Karnell MP
- Published
- 2000
5. Health-related quality of life among preadolescent children with oral clefts: the mother's perspective.
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Damiano PC, Tyler MC, Romitti PA, Momany ET, Jones MP, Canady JW, Karnell MP, and Murray JC
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- 2007
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- View/download PDF
6. Focus on technology. A better treatment foundation for children with VPI.
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Karnell MP, Bailey P, Johnson L, and Dragan A
- Published
- 2002
7. Quantitative Endoscopic Phototransducer Investigation of Normal Velopharyngeal Physiology.
- Author
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Karnell MP, Moon JB, Nakajima K, and Kacmarynski DS
- Subjects
- Adult, Analysis of Variance, Endoscopy instrumentation, Female, Fiber Optic Technology instrumentation, Humans, Male, Middle Aged, Phonetics, Sex Characteristics, Young Adult, Motor Activity physiology, Palate, Soft diagnostic imaging, Palate, Soft physiology, Pharynx diagnostic imaging, Pharynx physiology, Speech physiology
- Abstract
Purpose: The purpose of this research was to learn the extent to which healthy individuals vary in their ability to achieve velopharyngeal closure for speech., Method: Twenty healthy adult volunteers (10 women, 10 men) were tested using an endoscopic phototransducer system that tracks variations in velopharyngeal closure during speech production. Each speaker produced multiple repetitions of three utterances that differed in phonetic content. The data were amplitude normalized and averaged for each speaker., Results: Average phototransducer measurements were similar across subjects for utterances containing only oral phonemes. Average percentage of velopharyngeal closure varied considerably among subjects when producing utterances containing both oral and nasal phonemes (54%-95%). Average percentage of velopharyngeal closure levels were significantly lower (p < .05) for utterances that included nasal consonants., Conclusions: Phototransducer measurements of velopharyngeal closure for speech are sensitive to nasal phoneme content. The findings suggest that motor programming that accomplishes rapid oral-nasal velopharyngeal valving for speech may differ among healthy subjects. However, such variations in motor programming may not perceptually affect typical speakers. If present in individuals with abnormal velopharyngeal mechanisms, these variations may help explain variations among speakers in speech outcomes after physical and behavioral management.
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- 2016
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8. Association between severity of dysphagia and survival in patients with head and neck cancer.
- Author
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Shune SE, Karnell LH, Karnell MP, Van Daele DJ, and Funk GF
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- Age Factors, Aged, Carcinoma complications, Carcinoma pathology, Carcinoma therapy, Female, Head and Neck Neoplasms complications, Head and Neck Neoplasms pathology, Head and Neck Neoplasms therapy, Humans, Male, Middle Aged, Multivariate Analysis, Neoplasm Staging, Radiotherapy adverse effects, Retrospective Studies, Risk Factors, Sex Factors, Carcinoma mortality, Deglutition Disorders etiology, Head and Neck Neoplasms mortality, Severity of Illness Index
- Abstract
Background: This study examined risk factors for dysphagia, a common and serious condition in patients with head and neck cancer, and the association between severity of dysphagia and survival., Methods: Chart reviews were performed on patients diagnosed with head and neck cancer between January 2001 and April 2003, who had dysphagia diagnoses or swallowing evaluations. Regression analyses determined factors associated with dysphagia and the association between observed survival and severity of dysphagia., Results: Almost 50% of the 407 patients had dysphagia. Risk factors included advanced stage, older age, female sex, and hypopharyngeal tumors. The most severe dysphagia ([L.] nil per os or "nothing by mouth" status), which was associated with lower survival rates, was the strongest independent predictor of survival., Conclusions: Swallowing problems should be considered when determining appropriate cancer-directed treatment and posttreatment care. Because of dysphagia's high incidence rate and association with survival, a speech-language pathologist should be involved to ensure routine diagnostic and therapeutic swallowing interventions., (Copyright © 2011 Wiley Periodicals, Inc.)
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- 2012
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9. Instrumental assessment of velopharyngeal closure for speech.
- Author
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Karnell MP
- Subjects
- Articulation Disorders physiopathology, Articulation Disorders therapy, Child, Endoscopy, Equipment Design, Humans, Magnetic Resonance Imaging instrumentation, Speech Therapy, Tape Recording instrumentation, Velopharyngeal Insufficiency physiopathology, Velopharyngeal Insufficiency therapy, Video Recording instrumentation, Articulation Disorders diagnosis, Phonetics, Sound Spectrography instrumentation, Speech Intelligibility, Speech Production Measurement instrumentation, Velopharyngeal Insufficiency diagnosis, Voice Quality physiology
- Abstract
The presence of a palatal cleft at birth should not prevent good speech production in most children provided they have (1) appropriate surgical intervention to close the palate at or around the child's first birthday, (2) careful monitoring of speech development throughout childhood, (3) speech therapy when needed, and (4) secondary surgical or speech-prosthetic intervention when needed. When managed carefully by an experienced, well-prepared multidisciplinary team that applies the criteria listed above, ~70% of children with nonsyndromic palatal clefts will have no significant difficulties with speech intelligibility or speech quality due to velopharyngeal insufficiency by the time they enter elementary school. Speech assessment is the first step toward comprehensive team management of children with cleft palate. The purpose of this chapter is to describe the use of instrumentation in the evaluation of speech of children with palatal clefts, within the context of a multidisciplinary team. The focus of this article is on instruments that are used to supplement the perceptual assessment to document current speech status and plan management strategies., (© Thieme Medical Publishers.)
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- 2011
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10. Outcomes after the use of gastrostomy tubes in patients whose head and neck cancer was managed with radiation therapy.
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Ames JA, Karnell LH, Gupta AK, Coleman TC, Karnell MP, Van Daele DJ, and Funk GF
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- Aged, Deglutition Disorders etiology, Eating, Female, Follow-Up Studies, Head and Neck Neoplasms pathology, Humans, Male, Middle Aged, Mucositis complications, Survival Analysis, Time Factors, Weight Loss, Enteral Nutrition, Gastrostomy, Head and Neck Neoplasms mortality, Head and Neck Neoplasms radiotherapy
- Abstract
Background: The purpose of this study was to examine the effect of continued oral intake and duration of gastrostomy tube placement on posttreatment nutritional outcomes in patients being irradiated for head and neck cancer., Methods: Factors associated with continued oral intake and its association with posttreatment outcomes were analyzed., Results: Patients with no oral intake (39.6% of 91) were more likely to have laryngeal tumors, advanced disease, and pretreatment gastrostomy tube placement. Of the 55 patients whose gastrostomy tubes had been removed, those with continued oral intake and shorter gastrostomy tube placement were more likely to maintain their weight and report eating scores in the higher-functioning category, but have more restricted diets. Observed survival was significantly better for the continued-oral-intake group (p = .001)., Conclusion: The beneficial effects of continued oral intake and shorter gastrostomy tube placement on posttreatment outcomes shown in this study suggest that clinicians involved in these patients' care should emphasize oral intake during treatment., (Copyright © 2010 Wiley Periodicals, Inc.)
- Published
- 2011
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11. Cerebellum structure differences and relationship to speech in boys and girls with nonsyndromic cleft of the lip and/or palate.
- Author
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Conrad AL, Dailey S, Richman L, Canady J, Karnell MP, Axelson E, and Nopoulos P
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- Adolescent, Articulation Disorders diagnosis, Case-Control Studies, Child, Female, Humans, Image Processing, Computer-Assisted methods, Magnetic Resonance Imaging methods, Male, Organ Size, Sex Factors, Speech Disorders diagnosis, Velopharyngeal Insufficiency diagnosis, Voice Disorders diagnosis, Cerebellum pathology, Cleft Lip physiopathology, Cleft Palate physiopathology, Speech physiology
- Abstract
Objective: To identify regional cerebellar structural differences in boys and girls with nonsyndromic cleft of the lip and/or palate and determine whether these differences are related to speech impairment., Design: Between 2003 and 2007, measures on cerebellar volume were obtained on 43 children with nonsyndromic cleft of the lip and/or palate and 43 age- and sex-matched, healthy controls. Children with the cleft condition also received speech evaluations. Children with nonsyndromic cleft of the lip and/or palate were recruited from clinic records, and controls (screened for medical, psychiatric, speech/language, and behavioral concerns) were recruited from the local community. All tests were administered at a large midwestern hospital. Boys and girls with nonsyndromic cleft of the lip and/or palate were compared with the healthy controls on global and regional measures of cerebellar volume. Areas of significant difference were then correlated with measures of speech to assess relationships in children with nonsyndromic cleft of the lip and/or palate., Results: Boys with nonsyndromic cleft of the lip and/or palate had smaller cerebellums than controls (p = .002); whereas, for girls, only regional reductions in size reached significance (corpus medullare, p = .040). Cerebellum size was correlated with articulation for boys (p = .045)., Conclusions: These findings lend support to previous research documenting abnormal brain structure in children with nonsyndromic cleft of the lip and/or palate and suggest that the cerebellum may play a role in speech deficits along with other structural causes, at least in boys.
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- 2010
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12. Evaluation of open approach and injection laryngoplasty in revision thyroplasty procedures.
- Author
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Andrews BT, Van Daele DJ, Karnell MP, McCulloch TM, Graham SM, and Hoffman HT
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- Adolescent, Adult, Aged, Aged, 80 and over, Biocompatible Materials administration & dosage, Child, Durapatite administration & dosage, Female, Follow-Up Studies, Humans, Injections, Male, Middle Aged, Reoperation, Retrospective Studies, Treatment Outcome, Vocal Cord Paralysis physiopathology, Voice Quality, Larynx surgery, Prostheses and Implants, Prosthesis Implantation methods, Plastic Surgery Procedures methods, Thyroid Cartilage surgery, Vocal Cord Paralysis surgery
- Abstract
Introduction: Vocal outcomes after medialization laryngoplasty are variable and may change over time. A revision procedure via open approach or an injection laryngoplasty may be necessary to improve vocal outcomes., Methods: A retrospective chart review was performed., Results: Twenty-nine subjects were identified and stratified into group 1A (n = 9) if the allograft was repositioned/replaced, group 1B (n = 4) if the allograft was removed, and group 2 (n = 16) if an injection laryngoplasty was performed. Statistically significant differences were found between all data prerevision to postrevision (P < or = 0.05) for group 1A and group 2 when multiple paired-sample t tests were calculated for patient-reported voice severity ratings and voice impact ratings as well as clinician-reported voice ratings of grade, roughness, and breathiness. Results of group 2 were often temporary, with 10 of 16 (62.5%) subjects receiving multiple injections., Conclusion: Both open revision laryngoplasty and injection laryngoplasty are successful at providing improved vocal outcomes. Results are often temporary after injection laryngoplasty and often require multiple procedures.
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- 2008
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13. Reliability of clinician-based (GRBAS and CAPE-V) and patient-based (V-RQOL and IPVI) documentation of voice disorders.
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Karnell MP, Melton SD, Childes JM, Coleman TC, Dailey SA, and Hoffman HT
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- Adolescent, Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Observer Variation, Quality of Life psychology, Reproducibility of Results, Surveys and Questionnaires, Documentation, Patients, Professional Competence, Speech Perception, Voice Disorders diagnosis, Voice Disorders epidemiology
- Abstract
This study examined the reliability of two methods for documenting voice quality by clinicians and compared the methods for documenting patients' perceptions of voice quality. It involved a prospective reliability study and a retrospective chart review. Reliability of two clinician-based voice assessment protocols-Grade, Roughness, Breathiness, Asthenia, Strain (GRBAS) and Consensus Auditory Perceptual Evaluation-Voice (CAPE-V)-was evaluated. These two protocols were then compared after use in voice assessments of 42 males and 61 females performed by a certified speech-language pathologist specializing in the assessment of voice disorders. In addition, two patient-based scales (Voice Related Quality of Life, or V-RQOL, and Iowa Patient's Voice Index, or IPVI) obtained from the same patients were compared with each other and with the clinician-based scales. Reliability of clinicians' ratings of overall severity of dysphonia using GRBAS and CAPE-V scales was very good (r>0.80). Agreement between V-RQOL Total scores and IPVI ratings of the patient's perceptions of impact of dysphonia was less strong (Spearman's r=-0.76). There was relatively weak agreement between patient-based and clinician-based scales. Clinician's perceptions of dysphonia appeared to be reliable and unaffected by rating tool, as indicated by the high level of agreement between the two rating systems when they were used together. The CAPE-V system appeared to be more sensitive to small differences within and among patients than the GRBAS system. The V-RQOL and IPVI approaches to documenting patient's perceptions of dysphonia agreed less well possibly due to differences in patient dependence on voice and on interpretation of the rating tool items. The differences between clinician-based and patient-based data support the conclusion that clinicians and patients experience and consider dysphonia very differently.
- Published
- 2007
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14. Type of oral cleft and mothers' perceptions of care, health status, and outcomes for preadolescent children.
- Author
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Damiano PC, Tyler MC, Romitti PA, Momany ET, Canady JW, Karnell MP, and Murray JC
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- Achievement, Child, Child, Preschool, Cleft Lip classification, Cleft Lip therapy, Cleft Palate classification, Cleft Palate therapy, Esthetics, Female, Humans, Interviews as Topic, Iowa, Male, Mother-Child Relations, Mothers psychology, Personal Satisfaction, Population Surveillance, Social Adjustment, Social Class, Speech physiology, Treatment Outcome, Attitude to Health, Cleft Lip psychology, Cleft Palate psychology, Health Status
- Abstract
Objective: To evaluate the outcomes of care for children by type of oral cleft., Design: Data were collected through structured telephone interviews during 2003 in Iowa with mothers of 2- to 12-year-old children with oral clefts. Interviews with mothers of children with clubfoot and statewide data on Iowa children were used for comparison., Participants: Participants included mothers of children in Iowa born between 1990 and 2000 with nonsyndromic oral clefts. Children were identified by the statewide Iowa Registry for Congenital and Inherited Disorders., Main Outcome Measures: Rating of cleft care, severity of condition, health status, esthetic outcome, speech, and school performance were evaluated by type of oral cleft., Results: Children with cleft lip and palate were most likely to have their clefts rated as very severe. Children with palatal involvement were reported to have a lower health status and were almost twice as likely to be identified as having a special health care need compared with either children with cleft lip or children statewide. Children with cleft lip had more esthetic concerns; children with palatal involvement had the most speech concerns., Conclusions: Although mothers generally believed their children had received high-quality care, ratings of the children's current health status and outcomes of care varied significantly by type of cleft (cleft lip, cleft palate, and cleft lip and palate). Differences observed in this population-based study support the proposition that cleft type should be considered when examining outcomes of care for children with oral clefts.
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- 2006
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15. Comparison of clinician judgments and measurements of swallow response time: a preliminary report.
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Karnell MP and Rogus NM
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- Adult, Aged, Aged, 80 and over, Chi-Square Distribution, Female, Fluoroscopy methods, Humans, Male, Middle Aged, Reproducibility of Results, Video Recording, Deglutition physiology, Deglutition Disorders physiopathology, Judgment
- Abstract
Practicing clinicians frequently offer judgments about aspects of swallowing physiology rather than performing actual measurements. Little is known about the accuracy of those judgments. The purpose of this preliminary study was to explore agreement of clinicians' judgments of pharyngeal swallow response time (PSRT) with temporal measurements of PSRT. In preparation for a larger study, PSRT was measured from the first 3 ml liquid bolus swallow that appeared in each of 20 videofluorographic swallowing evaluations. The same 20 swallows were then shown to 3 clinicians who were instructed to subjectively rate PSRT. The reliability of the PSRT measurements was strong (r > .95). Intrajudge and interjudge agreement was better than chance in all but 1 interjudge comparison. Percentage agreement between clinicians' judgments and the measurements, when the measurements were categorized as either not delayed or delayed, ranged from 60% to 95%. Chi-square and Phi statistics comparing the outcomes of clinicians' ratings with the measurement outcomes were significant, supporting the agreement of the judgments with the measurements. Although the results of tests of agreement were found to be acceptable, clinician experience and training remain important issues whenever clinical judgments are involved. Larger studies are needed to establish the accuracy and importance of clinicians' judgments of PSRT and observations of swallowing physiology.
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- 2005
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16. Resonant voice: spectral and nasendoscopic analysis.
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Smith CG, Finnegan EM, and Karnell MP
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- Adult, Female, Glottis physiology, Humans, Larynx physiology, Male, Phonation physiology, Sound Spectrography methods, Vocal Cords physiology, Voice Quality, Endoscopy methods, Speech Acoustics, Voice physiology
- Abstract
Although resonant voice therapy is a widely used therapeutic approach, little is known about what characterizes resonant voice and how it is physiologically produced. The purpose of this study was to test the hypothesis that resonant voice is produced by narrowing the laryngeal vestibule and is characterized by first formant tuning and more ample harmonics. Videonasendoscopic recordings of the laryngeal vestibule were made during nonresonant and resonant productions of /i/ in six subjects. Spectrums of the two voice types were also obtained. Spectral analysis showed that first formant tuning was exhibited during resonant voice productions and that the degree of harmonic enhancement in the range of 2.0 to 3.5 kHz was related to voice quality: nonresonant voice had the least amount of energy in this range, whereas a resonant-relaxed voice had more energy, and a resonant-bright voice had the greatest amount of energy. Visual-perceptual judgments of the videoendoscopic data indicated that laryngeal vestibule constriction was not consistently associated with resonant voice production.
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- 2005
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17. Facilitating communication among speech pathologists treating children with cleft palate.
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Karnell MP, Bailey P, Johnson L, Dragan A, and Canady JW
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- Child, Cleft Palate complications, Clinical Protocols, Computer Security, Craniofacial Abnormalities complications, Endoscopy, Humans, Hypermedia, Online Systems, Patient Care Planning, Patient Care Team, Speech Disorders etiology, Speech Disorders therapy, Speech Intelligibility physiology, Treatment Outcome, Velopharyngeal Insufficiency complications, Video Recording, Cleft Palate rehabilitation, Communication, Internet, Interprofessional Relations, Speech-Language Pathology education
- Abstract
An interactive web-based system was designed to facilitate communication between nonspecialist speech pathologists who provide therapy for individuals with speech disorders associated with cleft palate or craniofacial anomalies and specialist speech pathologists who provide physiologically based assessments of speech production. The web site includes instructional presentations, streaming video clips of endoscopic examinations, and exchange of information about the nature of therapy as recommended by the specialist and as provided by the nonspecialist. The approach demonstrates use of web-based computer facilities to improve the quality of communication among professionals with the goal of improving the outcomes of speech therapy. Information from the site can also be used in academic training programs as a teaching tool in courses on cleft palate speech.
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- 2005
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18. Perceived phonatory effort and phonation threshold pressure across a prolonged voice loading task: a study of vocal fatigue.
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Chang A and Karnell MP
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- Adult, Differential Threshold, Female, Humans, Male, Sex Factors, Fatigue physiopathology, Phonation physiology, Vocal Cords physiology, Voice physiology, Voice Disorders physiopathology
- Abstract
Although the problem of vocal fatigue is not uncommon in people with voice disorders, research on objective quantifiable indicators of vocal fatigue is limited. It has been suggested that a speaker's perception of increased phonatory effort associated with periods of prolonged voice use is related to increased lung pressure required to initiate and sustain phonation. The purpose of this study was to examine the relationship among perceived phonatory effort (PPE), which was used as a subjective index of vocal fatigue, and phonation threshold pressure (PTP), a quantifiable measure defined as the minimal lung pressure required to initiate and sustain vocal fold oscillation. PTP and PPE were recorded before, during, and after five adult male and five adult female speakers engaged in a prolonged oral reading task designed to induce vocal fatigue. The results supported a direct, moderately strong relationship between PTP and PPE, particularly when PTP was measured during speech produced at comfortable and low-speaking pitch levels. No gender effects were found. PTP returned to baseline levels within 1 hour after the fatiguing task. PPE returned to baseline within 1 day. The data support the use of PTP as an objective index of vocal fatigue.
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- 2004
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19. Pharyngeal flap surgery: long-term outcomes at the University of Iowa.
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Cable BB, Canady JW, Karnell MP, Karnell LH, and Malick DN
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- Child, Follow-Up Studies, Humans, Retrospective Studies, Velopharyngeal Insufficiency physiopathology, Voice Quality, Pharynx surgery, Surgical Flaps, Velopharyngeal Insufficiency surgery
- Abstract
The pharyngeal flap is the most often used surgical approach to treat the problem of velopharyngeal insufficiency, a common challenge encountered in cleft palate and craniofacial clinics. The authors retrospectively reviewed short-term and long-term measures of children treated with the pharyngeal flap at the University of Iowa Cleft and Craniofacial Center. All patients who underwent pharyngeal flap surgery between January of 1970 and December of 2000, with at least one postoperative speech assessment between 2 and 5 years after the operation, were identified. Both hypernasality and hyponasality were evaluated on a scale from 1 to 6, with 1 indicating no involvement and 6 indicating severe effect on resonance. Velopharyngeal competence was also rated on a scale of 1 to 3, with 1 indicating competence and 3 indicating incompetence. These short-term data were then compared. The results showed that overall resonance performance continues to be adequate and may even improve as the patient continues to grow and mature. These findings support the use of the pharyngeal flap in the treatment of children with velopharyngeal insufficiency.
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- 2004
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20. Pharyngeal flap surgery: protocols, complications, and outcomes at the University of Iowa.
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Canady JW, Cable BB, Karnell MP, and Karnell LH
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- Adolescent, Adult, Analgesics, Opioid therapeutic use, Child, Child, Preschool, Female, Follow-Up Studies, Humans, Intraoperative Complications, Male, Nasopharynx surgery, Pain, Postoperative drug therapy, Polysomnography, Retrospective Studies, Severity of Illness Index, Voice Disorders diagnosis, Voice Disorders epidemiology, Palate, Soft surgery, Pharynx surgery, Postoperative Complications, Surgical Flaps, Velopharyngeal Insufficiency surgery, Voice Disorders etiology
- Abstract
Objective: We sought to assess complication rates and speech outcomes in patients undergoing pharyngeal flap surgery. Study design and setting We conducted a retrospective chart and database review at a tertiary craniofacial center., Patients: Eighty-seven patients were identified as having pharyngeal flaps between January 1990 and December 2000., Results: Complications were rare, with an overall rate of 3.4% for all children. Craniofacial database records were identified with a follow-up examination between 2 and 5 years. Forty-four patients were identified. Of this group, 81.8% demonstrated no evidence of hypernasality or mild hypernasality, and 84.1% demonstrated no evidence of hyponasality or only mild hyponasality. Preoperative and postoperative assessments showed a statistically significant difference in hypernasality at P < 0.001 with no significant difference in hyponasality., Conclusions: Although sphincter pharyngoplasty procedures have gained a great deal of attention in the recent otolaryngologic literature, pharyngeal-flap procedures remain a valuable tool in the hands of surgeons dealing with velopharyngeal incompetence.
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- 2003
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21. Investigations of a pressure-sensitive theory of marginal velopharyngeal inadequacy.
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Karnell MP, Schultz K, and Canady J
- Subjects
- Adolescent, Airway Resistance, Child, Child, Preschool, Cleft Lip complications, Cleft Palate complications, Endoscopy, Female, Humans, Male, Palate, Soft physiopathology, Pressure, Rhinomanometry, Speech Articulation Tests, Velopharyngeal Insufficiency complications, Video Recording, Velopharyngeal Insufficiency etiology, Velopharyngeal Insufficiency physiopathology, Voice Disorders etiology, Voice Disorders physiopathology
- Abstract
Purpose: This two-part project was designed to test a pressure-sensitive theory of marginal velopharyngeal inadequacy (MPVI). Specifically, are select subgroups of children with MPVI perceived as hypernasal because they fail to achieve consistent closure during vowels and semivowels while demonstrating adequate closure during pressure consonants?, Methods: In part one, 36 children with cleft palate and other craniofacial anomalies were examined using a clinical assessment protocol that included nasometry and perceived ratings of hypernasal resonance. Children with nasalance percentages above threshold during low-pressure (LP) productions and below threshold for high-pressure (HP) productions were placed in one group (group 1), while children with nasalance percentages below threshold for both LP and HP sentences were placed in another (group 2). Children in the two groups were age- and sex-matched. In part two, endoscopic data were examined for 10 additional children who received nasometry, perceived hypernasal resonance scores, and videoendoscopy on the same day and who received higher mean nasalance measures during production of LP sentences than during production of HP sentences., Results: The results of part one confirmed that children in group 1 were perceived as being significantly more hypernasal than children in group 2 (mean(group 1) = 2.17, mean(group 2) = 1.50; t = 2.75, p =.01). However, results of endoscopic testing failed to demonstrate a consistent observable physiologic pattern of velopharyngeal inadequacy that would confirm the theory that some patients with MVPI are perceived as being hypernasal because of difficulty achieving velopharyngeal closure during vowels and semivowels. CONCLUSIONS; The findings provide partial support for a pressure-sensitive theory of MVPI and demonstrate the value of using both HP and LP sentences to evaluate patients with MVPI.
- Published
- 2001
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22. Vocal fold paralysis secondary to cardiac countershock (cardioversion).
- Author
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Victoria L, Graham SM, Karnell MP, and Hoffman HT
- Subjects
- Aged, Aged, 80 and over, Female, Humans, Severity of Illness Index, Electric Countershock adverse effects, Vocal Cord Paralysis diagnosis, Vocal Cord Paralysis etiology
- Abstract
Application of electrical energy to the heart is effective in treating many dysrhythmias. There are, however, also disadvantages associated with cardioversion. Employment of external electrical current has been shown to induce epicardial and myocardial damage at the site of electrode application. We present the only case in the English literature of vocal fold paralysis in which the single identified associated event was cardioversion. In this case of temporary vocal fold paralysis, there was no invasive procedure to directly damage the nerve. Echocardiography of the patient revealed a large left atrium, placing the recurrent laryngeal nerve in an abnormal anatomic position where it was vulnerable to the electric current.
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- 1999
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23. A classification scheme for paradoxical vocal cord motion.
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Maschka DA, Bauman NM, McCray PB Jr, Hoffman HT, Karnell MP, and Smith RJ
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- Adolescent, Arnold-Chiari Malformation complications, Brain Injuries complications, Brain Stem pathology, Child, Conversion Disorder complications, Diagnosis, Differential, Factitious Disorders complications, Female, Gastroesophageal Reflux complications, Humans, Infant, Newborn, Laryngeal Diseases physiopathology, Magnetic Resonance Imaging, Male, Motor Neuron Disease complications, Motor Neuron Disease diagnosis, Movement Disorders complications, Movement Disorders diagnosis, Spinal Cord Compression complications, Spinal Cord Compression diagnosis, Laryngeal Diseases diagnosis, Laryngeal Diseases etiology, Vocal Cords physiopathology
- Abstract
Paradoxical vocal cord motion (PVCM) is characterized by the inappropriate adduction of the true vocal cords during inspiration. Multiple causes have been proposed for this group of disorders, which share the common finding of mobile vocal cords that adduct inappropriately during inspiration and cause stridor by approximation. Management of this group of disorders has been complicated by the lack of a classification scheme to include all types of PVCM. We propose that PVCM be classified according to its underlying etiology and recognize the following causes of the disorder: 1. brainstem compression; 2. cortical or upper motor neuron injury; 3. nuclear or lower motor neuron injury; 4. movement disorder; 5. gastroesophageal reflux; 6. factitious or malingering disorder; 7. somatization/conversion disorder. Case reports are presented to illustrate the characteristic features and diagnostic evaluation used in assessing patients with PVCM. Management varies depending on the cause of PVCM and entails speech therapy, pharmacologic therapy, behavioral modification, and/or surgical intervention. Recognition of the multiple causes of PVCM allows otolaryngologists to formulate well-directed diagnostic evaluation and treatment.
- Published
- 1997
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24. Comparison of fundamental frequency and perturbation measurements among three analysis systems.
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Karnell MP, Hall KD, and Landahl KL
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- Adolescent, Adult, Aged, Child, Female, Humans, Male, Middle Aged, Speech Acoustics, Tape Recording, Voice, Voice Quality
- Abstract
The need for standardization of procedures in approaches to voice measurement has been recently emphasized. The purpose of this study was to determine the extent to which the acoustic perturbation measurements from three different analysis systems agree when standardized recording and analysis procedures are used. High-quality acoustic voice recordings from 20 patients were analyzed. The results showed that, although fundamental frequency measurements were in strong agreement among the three systems tested, frequency and amplitude perturbation measurements were not in agreement. The underlying approaches to perturbation measurement appeared to be sufficiently different to produce different results. An argument is made for a standardized set of acoustic signals representing normal, dysphonic, and synthesized voices with known characteristics to facilitate testing of new acoustic analysis systems and confirm measurement accuracy and sensitivity.
- Published
- 1995
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25. Nasometric discrimination of hypernasality and turbulent nasal airflow.
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Karnell MP
- Subjects
- Acoustics, Diagnosis, Differential, Humans, Palate, Soft physiopathology, Pharynx physiopathology, Phonetics, Pressure, Speech physiology, Velopharyngeal Insufficiency classification, Velopharyngeal Insufficiency diagnosis, Nose physiopathology, Pulmonary Ventilation physiology, Speech Disorders diagnosis, Speech Perception
- Abstract
Agreement between nasalance measures and perception of nasality during speech is not consistently strong. A possible reason may be the complicating combined effects of nasal turbulent airflow and nasal resonance. The purpose of this preliminary study was to examine nasalance measures obtained during production of a low pressure speech sample designed to minimize or eliminate the effects of turbulent nasal airflow. The results showed that nasalance measures obtained as some of the subjects produced the new speech sample were significantly different from those obtained when the standard high pressure speech sample was used. Use of both the new low pressure samples and the standard high pressure samples may result in improved agreement between nasalance measures and ratings of speech nasality as well as assist in the identification of subgroups of patients with marginal velopharyngeal insufficiency.
- Published
- 1995
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26. Acoustic rhinometric measurements of changes in velar positioning.
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Seaver EJ, Karnell MP, Gasparaitis A, and Corey J
- Subjects
- Acoustics instrumentation, Cineradiography, Fluoroscopy, Humans, Male, Nasal Cavity physiology, Nasopharynx physiology, Palate, Soft physiology, Pharynx physiology, Pilot Projects, Pressure, Signal Processing, Computer-Assisted, Sound, Video Recording, Palate, Soft anatomy & histology, Pharynx anatomy & histology, Speech physiology
- Abstract
Acoustic rhinometry as a means to detect changes in velar position was examined in this study. Videofluoroscopic recordings were made of two normal speakers maintaining velopharyngeal open and velopharyngeal closed (silent /f/) targets. Simultaneous acoustic rhinometric recordings were made during the production of each stimulus. Determinations of changes in velar positioning during the closed samples were made from fluoroscopic recordings and compared to nasal cavity-nasopharynx changes detected by rhinometry. The excellent agreement between the measures from the two procedures (less than 1 cm) indicates that acoustic rhinometry is capable of detecting changes in velar positioning during "silent" speech. Implications for assessment and future research are discussed.
- Published
- 1995
- Full Text
- View/download PDF
27. Integrated endoscopic/photodetector evaluation of velopharyngeal function.
- Author
-
Karnell MP and Seaver EJ
- Subjects
- Adult, Bronchoscopes, Deglutition physiology, Electronics, Medical instrumentation, Endoscopes, Equipment Design, Fiber Optic Technology instrumentation, Humans, Male, Nose physiology, Oscillometry instrumentation, Pulmonary Ventilation physiology, Respiration physiology, Speech physiology, Speech Acoustics, Speech Disorders physiopathology, Surface Properties, Velopharyngeal Insufficiency diagnosis, Video Recording, Endoscopy methods, Palate, Soft physiology, Pharynx physiology, Velopharyngeal Insufficiency physiopathology
- Abstract
A new integrated videoendoscopic/photodetection system, including an endoscope with an internal instrument channel used for photodetection, was applied to the evaluation of velopharyngeal closure in a subject with marginal velopharyngeal insufficiency (VPI) and in a subject with no speech disorder. Acoustic and aerodynamic speech assessments were used to establish the severity of velopharyngeal impairment in the marginal VPI patient. A light-out condition was used to establish the photodetector criterion for closure. The new system was effective for providing detailed phonetic assessment of velopharyngeal closure. Variations in degree of closure during select oral and nasal consonant productions were identified in the VPI subject but not in the normal speaking subject. The data show that important details of velopharyngeal insufficiency can be identified using the integrated endoscopic/photodetection system.
- Published
- 1993
- Full Text
- View/download PDF
28. Videoendoscopy and photodetection: linearity of a new integrated system.
- Author
-
Covello LV, Karnell MP, and Seaver EJ
- Subjects
- Endoscopy methods, Equipment Design, Fiber Optic Technology instrumentation, Humans, Materials Testing, Models, Anatomic, Palate, Soft anatomy & histology, Pharynx anatomy & histology, Regression Analysis, Endoscopes, Light, Motion Pictures
- Abstract
Simultaneous videoendoscopy and photodetection has potential for improving the assessment of changes in velopharyngeal (VP) movements and closure over time during speech. The purpose of this project was to examine the linearity of a new system, including a pediatric bronchoscope with an internal instrument channel through which the photodetector fiber was positioned. The results led to the conclusion that the response of the new system was linear. However, further examination indicated that system positioning variables had important effects on the overall level of photodetector light detection. These observations confirm the importance of monitoring and controlling the position of the endoscope-photodetector apparatus in the nasopharynx when using the system to evaluate velopharyngeal movement and closure for speech.
- Published
- 1992
- Full Text
- View/download PDF
29. Comparison of acoustic voice perturbation measures among three independent voice laboratories.
- Author
-
Karnell MP, Scherer RS, and Fischer LB
- Subjects
- Adult, Algorithms, Female, Humans, Laboratories, Male, Microcomputers, Minicomputers, Signal Processing, Computer-Assisted, Speech Acoustics, Phonation, Voice Disorders diagnosis, Voice Quality
- Abstract
The purpose of this study was to compare jitter and shimmer data measured with three different analysis systems, the Visi-Pitch PC system (Pine Brook) and two systems based on minicomputers (Chicago and Denver), as a preliminary step toward establishing recording and analysis standards. The results show that, although similar hardware and software used at independent laboratories can yield similar findings, differences in recording hardware as well as recording and analysis procedures can result in important differences in perturbation findings. Jitter measurements obtained with the Visi-Pitch were not consistently in good agreement with jitter measurements obtained from the minicomputer systems due, in part, to an interaction between the Visi-Pitch internal filter selected during the recording process and the novel method of pitch period determination used in the Visi-Pitch. Magnitude of shimmer measurements differed between the two minicomputer systems, in part because of differences in amplitude resolution of the A/D converters and recording noise. The correlation between the two shimmer data sets was relatively high, however, indicating that relative changes across utterances were comparable in spite of magnitude differences.
- Published
- 1991
- Full Text
- View/download PDF
30. Laryngeal perturbation analysis: minimum length of analysis window.
- Author
-
Karnell MP
- Subjects
- Adult, Humans, Sound Spectrography standards, Speech Production Measurement standards, Voice Disorders physiopathology, Voice Quality, Noise, Sound Spectrography methods, Speech Acoustics, Speech Production Measurement methods, Voice Disorders diagnosis
- Abstract
Laryngeal perturbation measures have been applied to the analysis of cycle-to-cycle changes in periodicity and amplitude of the acoustic voice signal for more than 25 years. Although such measures enjoy widespread clinical application, there is little agreement about basic methodology, including the length of signal to be analyzed. The purpose of this study was to examine changes in laryngeal perturbation measures as a function of length of signal analyzed in 18 subjects who complained of symptoms of possible laryngeal dysfunction. The results showed that as many as 190 cycles may be necessary before jitter asymptotes and as many as 130 cycles may be necessary before shimmer asymptotes. Pathological voices may require a longer analysis window for perturbation analysis than do nonpathological voices.
- Published
- 1991
- Full Text
- View/download PDF
31. Standardization for the reporting of nasopharyngoscopy and multiview videofluoroscopy: a report from an International Working Group.
- Author
-
Golding-Kushner KJ, Argamaso RV, Cotton RT, Grames LM, Henningsson G, Jones DL, Karnell MP, Klaiman PG, Lewin ML, and Marsh JL
- Subjects
- Cineradiography, Endoscopy methods, Fluoroscopy methods, Humans, Nasopharynx physiology, Palate, Soft anatomy & histology, Palate, Soft physiology, Pharynx anatomy & histology, Pharynx physiology, Speech physiology, Uvula anatomy & histology, Uvula physiology, Velopharyngeal Insufficiency pathology, Velopharyngeal Insufficiency physiopathology, Endoscopy standards, Fluoroscopy standards, Nasopharynx anatomy & histology, Video Recording
- Abstract
A multidisciplinary International Working Group of scientists was assembled to address the question of standardizing reporting techniques for multiview videofluoroscopy and nasopharyngoscopy, the generally accepted standards for direct observation of the velopharyngeal valve. This report is a first attempt to propose standards while seeking feedback from the readership in order to further develop a common methodology.
- Published
- 1990
- Full Text
- View/download PDF
32. Longitudinal speech performance in patients with cleft palate: comparisons based on secondary management.
- Author
-
Karnell MP and Van Demark DR
- Subjects
- Adolescent, Articulation Disorders physiopathology, Child, Child, Preschool, Cleft Lip surgery, Humans, Speech Articulation Tests, Velopharyngeal Insufficiency physiopathology, Voice Quality, Cleft Lip physiopathology, Speech Disorders physiopathology
- Abstract
Speech performance of three groups of speakers with cleft palate was analyzed at two-year intervals from age 4 years through age 16 years. The three groups consisted of: Group A--individuals who score below 20 percent correct on the Iowa Pressure Articulation Test (IPAT) at 4 years of age and who received secondary surgery by 8 years of age; Group B--individuals who scored below 20 percent correct on the Iowa Pressure Articulation Test at 4 years of age, but did not receive secondary management by 8 years of age; and Group C--individuals who scored above 20 percent correct on the Iowa Pressure Articulation Test and who did not receive secondary surgery by 8 years of age. The results demonstrated that Group A performed better on several measures of speech performance at 16 years of age than either of the other groups. Also, speech performance appeared to become slightly worse around 12 years of age for Group B. This may be interpreted as evidence that this group may have been negatively affected by the physiologic changes associated with puberty. The other two groups did not appear to show this effect. The results of this study emphasize the need for careful research regarding patients who, in spite of early poor speech performance, are not considered candidates for early secondary management.
- Published
- 1986
33. Reliability of the nasopharyngeal fiberscope (NPF) for assessing velopharyngeal function.
- Author
-
Ibuki K, Karnell MP, and Morris HL
- Subjects
- Adult, Cineradiography, Endoscopy methods, Evaluation Studies as Topic, Female, Fiber Optic Technology instrumentation, Humans, Male, Middle Aged, Speech physiology, Endoscopes, Nasopharynx, Palate, Soft physiology, Pharynx physiology
- Abstract
Simultaneous side-view nasopharyngeal fiberscopic (NPF) and lateral cinefluoroscopic (cine) recordings were taken for two normal subjects to determine the stability of NPF placement for the study of velopharyngeal function, and the reliability and validity of NPF findings. The results indicate that the NPF was highly stable during the several velopharyngeal activities examined, the NPF tip maintaining a relatively constant relationship within the vertebral complex. Therefore, it seems likely that similar NPF views are obtained on different occasions with a subject. The findings also indicate that measurements can be made from NPF still photos for several aspects of the velopharyngeal mechanism. However, measurements of the left lateral wall movement were not reliable. Measurement of velar movement from NPF correlated well with cine measures of velar movement, indicating validity of that NPF measure.
- Published
- 1983
34. Reliability of the nasopharyngeal fiberscope (NPF) for assessing velopharyngeal function: analysis by judgment.
- Author
-
Karnell MP, Ibuki K, Morris HL, and Van Demark DR
- Subjects
- Cineradiography, Fiber Optic Technology, Humans, Nasopharynx, Palate, Soft diagnostic imaging, Pharynx diagnostic imaging, Speech physiology, Endoscopy methods, Palate, Soft physiology, Pharynx physiology
- Abstract
The reliability and validity of data about velopharyngeal function obtained with the nasopharyngeal fiberscope was assessed in normal subjects. The experimental design included data reduction procedures that are likely to have clinical utility (clinical ratings). The results indicated that relative velar movement and size of the velopharyngeal port may be reliably and validly estimated using the procedures. However NPF estimates of lateral pharyngeal wall movement were not reliable. Finally, the data indicated that velar movement and size of V-P port were consistent within subjects and tasks across data collection sessions. Data about consistency of lateral wall movement across sessions was inconclusive, however. Additional research involving similar procedures with subjects who have morphologic deficits is indicated.
- Published
- 1983
35. The effect of vowel context on consonantal intraoral air pressure.
- Author
-
Karnell MP and Willis CR
- Subjects
- Adult, Female, Humans, Manometry, Mouth, Phonation, Phonetics, Semantics, Voice
- Published
- 1982
- Full Text
- View/download PDF
36. Relationships between the perception of nasalization and speech movements in speakers with cleft palate.
- Author
-
Karnell MP, Folkins JW, and Morris HL
- Subjects
- Adult, Cleft Palate complications, Female, Humans, Jaw physiopathology, Movement, Palate, Soft physiopathology, Pharynx physiopathology, Speech Acoustics, Speech Disorders etiology, Speech Disorders physiopathology, Tongue physiopathology, Cleft Palate physiopathology, Speech physiology
- Abstract
The purpose of this study was to examine the relationships between several temporal measures of speech movements and perceived nasalization in speakers with cleft palate. Four adult subjects with repaired cleft palate were filmed using high-speed (100 frames/s) cinefluorography as they produced target syllables embedded in a carrier phrase. Perceived nasalization of each extracted acoustic target syllable was rated by 18 trained judges. Movements of the tongue tip, tongue dorsum, jaw, velar knee, velar tip, and posterior pharyngeal wall were plotted over time. Time of movement onsets and movement offsets was identified from the plots. Voice onset and offset times were identified from the synchronized acoustic recordings. The findings indicate that normally expected velopharyngeal movements occurred near the time of jaw-lowering onset during nasalized CVC and CVN productions in two subjects who were judged to exhibit high levels of nasalization. The other two subjects showed no velopharyngeal movements during the CVC production. It is speculated that velopharyngeal movements normally expected in CVC utterances may be avoided by some speakers with cleft palate in order to minimize perceptible nasalization.
- Published
- 1985
- Full Text
- View/download PDF
37. A comparison of photodetector and endoscopic evaluations of velopharyngeal function.
- Author
-
Karnell MP, Seaver EJ 3rd, and Dalston RM
- Subjects
- Female, Fiber Optic Technology, Humans, Judgment, Male, Photography, Visual Fields, Endoscopy, Palate, Soft physiology, Pharynx physiology, Video Recording
- Abstract
Simultaneous videoendoscopic and photodetection analyses were made of specific onset and offset times of velopharyngeal opening and closing in two normal speaking subjects. Both procedures were found to have acceptable measurement repeatability and to agree with each other when used to determine movement changes. It is felt that when used together, these techniques contribute to improved understanding of velopharyngeal activity during speech.
- Published
- 1988
- Full Text
- View/download PDF
38. The reliability of the Kay Agnellograph Pressure Translator in the study of consonantal intraoral air pressure.
- Author
-
Karnell MP and Willis CR
- Subjects
- Female, Humans, Speech, Transducers, Pressure, Speech Production Measurement instrumentation
- Published
- 1982
- Full Text
- View/download PDF
39. Nasal videoendoscopy in prosthetic management of palatopharyngeal dysfunction.
- Author
-
Karnell MP, Rosenstein H, and Fine L
- Subjects
- Endoscopes, Equipment Design, Humans, Speech Disorders physiopathology, Velopharyngeal Insufficiency physiopathology, Video Recording instrumentation, Endoscopy methods, Fiber Optic Technology instrumentation, Nose physiopathology, Palatal Obturators, Velopharyngeal Insufficiency rehabilitation, Video Recording methods
- Abstract
Application of nasal videoendoscopic procedures simplifies and objectifies design of an obturator prosthesis. Although oral videoendoscopic techniques are also valuable, the nasal perspective provides valuable information not visible from the oral perspective. Because the primary function of the obturator prosthesis is to eliminate hypernasal speech and perceived nasal emission of air associated with palatopharyngeal insufficiency, nasal videoendoscopy should be considered to verify proper soft tissue-obturator contact during speech.
- Published
- 1987
- Full Text
- View/download PDF
40. Multiview videoendoscopic evaluation of velopharyngeal physiology in 15 normal speakers.
- Author
-
Karnell MP and Morris HL
- Subjects
- Female, Humans, Male, Patient Compliance, Photography, Reference Values, Endoscopy methods, Palate, Soft physiology, Pharynx physiology, Speech physiology
- Abstract
Oral and nasal videoendoscopic procedures, when used in tandem, could provide a more useful analysis of velopharyngeal physiology than either procedure used alone. The purposes of this research were to document observed differences between the two approaches when applied to the examination of velopharyngeal function and to determine the advantages and disadvantages of using oral and nasal endoscopy as tandem diagnostic tools. The results indicated that patterns of velopharyngeal closure as observed from both the oral and nasal views are in approximately 60% agreement. Differences between the two perspectives most frequently involve the relative contributions of the pharyngeal walls. These differences are attributed to important physiologic variations along the vertical plane of the velopharynx. The data indicate that using oral and nasal videoendoscopy as tandem diagnostic procedures can result in improved understanding of velopharyngeal physiology. The issues of interference with speech movements and patient compliance are discussed.
- Published
- 1985
41. Variations in velar position over time: a nasal videoendoscopic study.
- Author
-
Karnell MP, Linville RN, and Edwards BA
- Subjects
- Air Pressure, Endoscopy, Female, Humans, Jaw physiology, Male, Movement, Nose, Phonetics, Speech Acoustics, Velopharyngeal Insufficiency diagnosis, Videotape Recording, Palate, Soft physiology, Speech physiology
- Abstract
Changes in velar position during production of nonnasal speech in two adults were measured using field-by-field videoendoscopic tracking procedures. The data suggested that the changes in velar position were coordinated with syllable production. Peak velar displacement occurred during maximum oral closure for oral consonant production and was followed by lowering of velar position during vowel production. This pattern of velar movement was not altered by changes in speaking rate or by jaw fixation. The timing of peak velar elevation relative to peak intraoral air pressure and peak jaw elevation was also examined. Timing of peak velar displacement was statistically associated with timing of peak intraoral air pressure in one subject. The data are discussed with regard to the potential value of studying variations in velar position during nonnasal speech in patients with marginal velopharyngeal incompetence.
- Published
- 1988
- Full Text
- View/download PDF
42. Synchronized videostroboscopic and electroglottographic examination of glottal opening.
- Author
-
Anastaplo S and Karnell MP
- Subjects
- Adult, Electrophysiology methods, Female, Humans, Male, Glottis physiology, Video Recording methods
- Abstract
Interpretation of electroglottography (EGG) as an index of glottal contact area has been complicated by difficulty obtaining independent validation measures. The purpose of this research was to implement a new simultaneous EGG/videostroboscopic technique for the evaluation of the relationship between a discontinuity in the opening phase of the EGG waveform with the onset of glottal opening viewed via videostroboscopy. The results support previous suggestions that this EGG discontinuity, when observed in nonpathologic individuals, usually marks the onset of glottal opening along the superior surface of the vocal folds.
- Published
- 1988
- Full Text
- View/download PDF
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