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16 results on '"Karska, Julia"'

11. Correlations between Dementia and Loneliness.

Author

Karska, Julia, Pszczołowska, Magdalena, Gładka, Anna, and Leszek, Jerzy

Subjects
*PSYCHOTIC depression, *LONELINESS, *DEMENTIA, *CEREBRAL atrophy, *SENSORY stimulation
Abstract

This review describes associations between dementia and loneliness on the neurobiological and epidemiological levels according to the recent body of literature. The aim of this study was to highlight major lines of research in this field. Sociocognitive skills and social interactions present complex interdependencies with dementia which may be explained by two theories. According to the first one, not sufficiently engaging in social or cognitive activities results in brain atrophy. The second one claims that brain neurogenesis and synaptic density are being increased by social connections. The relationship between loneliness and dementia could be mediated by sensory loss, including hearing and visual impairment, as well as depression and psychotic symptoms. Loneliness itself might cause a depletion in sensory and cognitive stimulation which results in a decrease in neural reserve. Certain changes in the structures of the brain caused by loneliness were found in imaging examination. Loneliness appears to be a crucial risk factor for dementia in recent times due to the modern lifestyle and consequences of the outbreak of COVID-19. Additional studies are required to understand more completely the key tenets of this topic and therefore to improve the prevention and treatment of dementia. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Cognitive Decline in Early and Premature Menopause

Author

Sochocka, Marta, primary, Karska, Julia, additional, Pszczołowska, Magdalena, additional, Ochnik, Michał, additional, Fułek, Michał, additional, Fułek, Katarzyna, additional, Kurpas, Donata, additional, Chojdak-Łukasiewicz, Justyna, additional, Rosner-Tenerowicz, Anna, additional, and Leszek, Jerzy, additional

Published
2023
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15. Interleukin 17 and Its Involvement in Renal Cell Carcinoma

Author

Jarocki, Michał, primary, Karska, Julia, additional, Kowalski, Szymon, additional, Kiełb, Paweł, additional, Nowak, Łukasz, additional, Krajewski, Wojciech, additional, Saczko, Jolanta, additional, Kulbacka, Julita, additional, Szydełko, Tomasz, additional, and Małkiewicz, Bartosz, additional

Published
2022
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16. Artificial light and neurodegeneration: does light pollution impact the development of Alzheimer’s disease?

Author

Karska, Julia, Kowalski, Szymon, Gładka, Anna, Brzecka, Anna, Sochocka, Marta, Kurpas, Donata, Beszłej, Jan Aleksander, and Leszek, Jerzy

Abstract

Two multidimensional problems of recent times — Alzheimer’s disease and light pollution — seem to be more interrelated than previously expected. A series of studies in years explore the pathogenesis and the course of Alzheimer’s disease, yet the mechanisms underlying this pathology remain not fully discovered and understood. Artificial lights which accompany civilization on a daily basis appear to have more detrimental effects on both environment and human health than previously anticipated. Circadian rhythm is affected by inappropriate lighting conditions in particular. The consequences are dysregulation of the sleep-wake cycle, gene expression, neuronal restructuring, brain’s electricity, blood flow, metabolites’ turnover, and gut microbiota as well. All these phenomena may contribute to neurodegeneration and consequently Alzheimer’s disease. There is an increasing number of research underlining the complexity of the correlation between light pollution and Alzheimer’s disease; however, additional studies to enhance the key tenets are required for a better understanding of this relationship.

Published
2023
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