Search

Michael F Diejomaoh,1,2 Zainab Bello,2 Waleed Al Jassar,1,2 Jiri Jirous,2 Kavitha Karunakaran,2 Asiya T Mohammed11Department of Obstetrics and Gynaecology, Faculty of Medicine, Kuwait University, Safat, 2Maternity Hospital, Shuwaikh, Kuwait Background: Recurrent spontaneous miscarriage (RSM) has a multifactorial etiology, mainly due to karyotype abnormalities including balanced translocation, anatomical uterine disorders, and immunological factors, although in 50%–60% the etiology is unexplained. The treatment of RSM remains challenging, and the role of intravenous immunoglobulin (IVIG) in RSM is controversial. Case report: Mrs HM, 37 years old, obstetric summary: P0+1+13+1, a known case of hypothyroidism/polycystic ovary syndrome, married to an unrelated 47-year-old man, presented to our RSM clinic in early January 2014 for investigation and treatment. She has had multiple failed in vitro fertilization trials and 13 first-trimester missed miscarriages terminating at 6–7 weeks, all without IVIG therapy. Her tenth pregnancy was spontaneous, managed in London, UK, with multiple supportive therapy and courses of IVIG starting from the third to the 30th week of pregnancy. The pregnancy ended at 36 weeks of gestation with a cesarean section and a live girl baby was delivered. Mrs HM had balanced translocation, 46XX t (7:11) (p10:q10). Preimplantation genetic diagnosis/intracytoplasmic sperm injection/in vitro fertilization was performed with embryo transfer on May 29, 2014, and resulted in a successful pregnancy. She was commenced immediately on metformin, luteal support, and IVIG therapy, started at 6 weeks of gestation and at monthly intervals until 30 weeks of gestation, and also received additional therapy. The pregnancy was monitored with ultrasound, progressed uneventfully until admission at 35 weeks of gestation, with mildly elevated liver enzymes and suspected fetal growth restriction. She was managed conservatively, and in the light of nonreassuring fetal status, a live female infant weighing 2.29 kg was delivered by emergency cesarean section on January 14, 2015, with an Apgar score of 8 and 9 and mild respiratory distress, and was admitted to the Special Care Baby Unit for intensive therapy. The mother and baby made satisfactory progress and were discharged on January 24, 2015. Conclusion: Two consecutive successful pregnancies in Mrs HM with multiple causes of RSM treated with other medications and IVIG strongly suggest that IVIG has a positive role in RSM. Keywords: recurrent, miscarriage, intravenous immunoglobulin, pregnancy outcome

By considering the unique performances, the Powder Mixed Electrical Discharge Machining (PMEDM) mostly encounter choice for machining the hard materials with job features like intricate shapes with grater accuracy and those materials are difficult to cut in conventional machining processes. This Research aimed to prepare parameter index chart for machining nickel based super alloy - Inconel 800 for various requirements. To achieve the aim, In this experimental study on machining of Inconel 800 in PMEDM with electrolyte copper electrode as well as silver coated electrolyte copper electrode is focused. Taguchi full factorial design derived from MINITAB release-16 software was used to design the experimentation. The factors like pulse off time, Current and Pulse on Time were considered. The responses like amount of Tool Wear, Quantity of material removal, surface finishes were noted against each case. In the same experimental conditions the coated electrode increased the MRR by 36.67% with minor increment of maximum surface roughness to 16.11%.

In the ever-evolving landscape of digital marketing, the role of social media in shaping effective communication strategies is paramount. This research paper delves into the world of data-driven insights to examine how social media channels contribute to the success of digital communication efforts. This paper focuses on exploring the multifaceted aspects of social media's impact on brand visibility, engagement, and customer interaction. The data was analyzed quantitatively using descriptive statistics while Analysis of Variance was used to establish associations between variables. The study revealed that major factors influencing the social media's effectiveness in digital communication are Content, Customer Interaction and Social Media metrics. As a result of comprehensive analysis, this research paper not only provides valuable insights into the current state of social media's effective-ness in digital communication but also offers practical recommendations for businesses looking to optimize their social media strategies. In an era where data reigns supreme, this research findings serve as a guide for harnessing the power of social media as a dynamic and influential tool in the digital communication arsenal. [ABSTRACT FROM AUTHOR]

This study examines the impact of poor tank performance in Andhra Pradesh, India, focusing on nonsystem and system tanks. Data analysis reveals declining tank performance over the past three decades, with average performance at 58.39% for non-system tanks and 87.4% for system tanks in 2021. Non-system tanks show favourable gross farm revenue and water user association characteristics, with siltation negatively affecting the performance. System tanks benefit from better foreshore and water spread area maintenance, reducing siltation and encroachment issues. Recommendations include Government initiatives for desiltation, strengthening water user associations, and promoting less waterintensive crops to address tank performance challenges. [ABSTRACT FROM AUTHOR]