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471 results on '"Kasapçopur Özgür"'

1. Towards a standardized program of transitional care for adolescents with juvenile idiopathic arthritis for Turkey: a national survey study

Author

Sözeri, Betül, Şahin, Nihal, Açarı, Ceyhun, Avar Aydın, Pinar Ozge, Baba, Ozge, Bağlan, Esra, Bakkaloğlu, Sevcan, Bakırcı, Sibel, Bilginer, Yelda, Bozkaya, Burcu Yücel, Çağlayan, Şengül, Çakan, Mustafa, Çakmak, Figen, Coşkuner, Taner, Demir, Ferhat, Demirkan, Fatma Gül, Doğantan, Şeyda, Adıgüzel Dündar, Hatice, Ersözlü, Emine Duygu, Gücenmez, Sercan, Gürler, Oğuz, İşgüder, Rana, Küçük, Adem, Kalyoncu, Mukaddes, Kılıç, Levent, Kılıç, Sara Şebnem, Kısaoğlu, Hakan, Paç Kısaarslan, Ayşenur, Kızıldağ, Zehra, Kurtuluş, Duygu, Özdel, Semanur, Öztürk, Kübra, Şenol, Pelin, Tanatar, Ayşe, Taşkın, Sema Nur, Tuncer Kuru, Fatma, Türkuçar, Serkan, Ulu, Kadir, Ünsal, Erbil, Yazıcı, Ayten, Gezgin Yıldırım, Deniz, Yüksel, Selçuk, Kasapçopur, Özgür, Özen, Seza, Aktay Ayaz, Nuray, and Sönmez, Hafize Emine

Published
2024
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2. Interleukin (IL)-1/IL-6-Inhibitor–Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses

Author

Aamir, R., Abulaban, K., Adams, A., Lapsia, C. Aguiar, Akinsete, A., Akoghlanian, S., Al Manaa, M., AlBijadi, A., Allenspach, E., Almutairi, A., Alperin, R., Amarilyo, G., Ambler, W., Amoruso, M., Angeles-Han, S., Ardoin, S., Armendariz, S., Asfaw, L., Aviran Dagan, N., Bacha, C., Balboni, I., Balevic, S., Ballinger, S., Baluta, S., Barillas-Arias, L., Basiaga, M., Baszis, K., Baxter, S., Becker, M., Begezda, A., Behrens, E., Beil, E., Benseler, S., Bermudez-Santiago, L., Bernal, W., Bigley, T., Bingham, C., Binstadt, B., Black, C., Blackmon, B., Blakley, M., Bohnsack, J., Boneparth, A., Bradfield, H., Bridges, J., Brooks, E., Brothers, M., Brunner, H., Buckley, L., Buckley, M., Bukulmez, H., Bullock, D., Canna, S., Cannon, L., Canny, S., Cartwright, V., Cassidy, E., Castro, D., Chalom, E., Chang, J., Chang, M., Chang-Hoftman, A., Chen, A., Chiraseveenuprapund, P., Ciaglia, K., Co, D., Cohen, E., Collinge, J., Conlon, H., Connor, R., Cook, K., Cooper, A., Cooper, J., Corbin, K., Correll, C., Cron, R., Curry, M., Dalrymple, A., Datyner, E., Davis, T., De Ranieri, D., Dean, J., DeCoste, C., Dedeoglu, F., DeGuzman, M., Delnay, N., DeSantis, E., Devine, R., Dhalla, M., Dhanrajani, A., Dissanayake, D., Dizon, B., Drapeau, N., Drew, J., Driest, K., Du, Q., Duncan, E., Dunnock, K., Durkee, D., Dvergsten, J., Eberhard, A., Ede, K., Edelheit, B., Edens, C., El Tal, T., Elder, M., Elzaki, Y., Fadrhonc, S., Failing, C., Fair, D., Favier, L., Feldman, B., Fennell, J., Ferguson, P., Ferguson, I., Figueroa, C., Flanagan, E., Fogel, L., Fox, E., Fox, M., Franklin, L., Fuhlbrigge, R., Fuller, J., Furey, M., Futch-West, T., Gagne, S., Gennaro, V., Gerstbacher, D., Gilbert, M., Gironella, A., Glaser, D., Goh, I., Goldsmith, D., Gorry, S., Goswami, N., Gottlieb, B., Graham, T., Grevich, S., Griffin, T., Grim, A., Grom, A., Guevara, M., Hahn, T., Halyabar, O., Hamda Natur, M., Hammelev, E., Hammond, T., Harel, L., Harris, J., Harry, O., Hausmann, J., Hay, A., Hays, K., Hayward, K., Henderson, L., Henrickson, M., Hersh, A., Hickey, K., Hiraki, L., Hiskey, M., Hobday, P., Hoffart, C., Holland, M., Hollander, M., Hong, S., Horton, D., Horwitz, M., Hsu, J., Huber, A., Huberts, A., Huggins, J., Huie, L., Hui-Yuen, J., Ibarra, M., Imlay, A., Imundo, L., Inman, C., Jackson, A., James, K., Janow, G., Jared, S., Jiang, Y., Johnson, L., Johnson, N., Jones, J., Kafisheh, D., Kahn, P., Kaidar, K., Kasinathan, S., Kaur, R., Kessler, E., Kienzle, B., Kim, S., Kimura, Y., Kingsbury, D., Kitcharoensakkul, M., Klausmeier, T., Klein, K., Klein-Gitelman, M., Knight, A., Kovalick, L., Kramer, S., Kremer, C., Kudas, O., LaFlam, T., Lang, B., Lapidus, S., Lapin, B., Lasky, A., Lawler, C., Lawson, E., Laxer, R., Lee, P., Lee, T., Lee, A., Leisinger, E., Lentini, L., Lerman, M., Levinsky, Y., Levy, D., Li, S., Lieberman, S., Lim, L., Limenis, E., Lin, C., Ling, N., Lionetti, G., Livny, R., Lloyd, M., Lo, M., Long, A., Lopez-Peña, M., Lovell, D., Luca, N., Lvovich, S., Lytch, A., Ma, M., Machado, A., MacMahon, J., Madison, J., Mannion, M., Manos, C., Mansfield, L., Marston, B., Mason, T., Matchett, D., McAllister, L., McBrearty, K., McColl, J., McCurdy, D., McDaniels, K., McDonald, J., Meidan, E., Mellins, E., Mian, Z., Miettunen, P., Miller, M., Milojevic, D., Mitacek, R., Modica, R., Mohan, S., Moore, T., Moore, K., Moorthy, L., Moreno, J., Morgan, E., Moyer, A., Murante, B., Murphy, A., Muscal, E., Mwizerwa, O., Najafi, A., Nanda, K., Nasah, N., Nassi, L., Nativ, S., Natter, M., Nearanz, K., Neely, J., Newhall, L., Nguyen, A., Nigrovic, P., Nocton, J., Nolan, B., Nowicki, K., Oakes, R., Oberle, E., Ogbonnaya-Whittesley, S., Ogbu, E., Oliver, M., Olveda, R., Onel, K., Orandi, A., Padam, J., Paller, A., Pan, N., Pandya, J., Panupattanapong, S., Toledano, A. Pappo, Parsons, A., Patel, J., Patel, P., Patrick, A., Patrizi, S., Paul, S., Perfetto, J., Perron, M., Peskin, M., Ponder, L., Pooni, R., Prahalad, S., Puplava, B., Quinlan-Waters, M., Rabinovich, C., Rafko, J., Rahimi, H., Rampone, K., Ramsey, S., Randell, R., Ray, L., Reed, A., Reid, H., Reiff, D., Richins, S., Riebschleger, M., Rife, E., Riordan, M., Riskalla, M., Robinson, A., Robinson, L., Rodgers, L., Rodriquez, M., Rogers, D., Ronis, T., Rosado, A., Rosenkranz, M., Rosenwasser, N., Rothermel, H., Rothman, D., Rothschild, E., Roth-Wojcicki, E., Rouster-Stevens, K., Rubinstein, T., Rupp, J., Ruth, N., Sabbagh, S., Sadun, R., Santiago, L., Saper, V., Sarkissian, A., Scalzi, L., Schahn, J., Schikler, K., Schlefman, A., Schmeling, H., Schmitt, E., Schneider, R., Schulert, G., Schultz, K., Schutt, C., Seper, C., Sheets, R., Shehab, A., Shenoi, S., Sherman, M., Shirley, J., Shishov, M., Siegel, D., Singer, N., Sivaraman, V., Sloan, E., Smith, C., Smith, J., Smitherman, E., Soep, J., Son, Mary B., Sosna, D., Spencer, C., Spiegel, L., Spitznagle, J., Srinivasalu, H., Stapp, H., Steigerwald, K., Stephens, A., Sterba Rakovchik, Y., Stern, S., Stevens, B., Stevenson, R., Stewart, K., Stewart, W., Stingl, C., Stoll, M., Stringer, E., Sule, S., Sullivan, J., Sundel, R., Sutter, M., Swaffar, C., Swayne, N., Syed, R., Symington, T., Syverson, G., Szymanski, A., Taber, S., Tal, R., Tambralli, A., Taneja, A., Tanner, T., Tarvin, S., Tate, L., Taxter, A., Taylor, J., Tesher, M., Thakurdeen, T., Theisen, A., Thomas, B., Thomas, L., Thomas, N., Ting, T., Todd, C., Toib, D., Torok, K., Tory, H., Toth, M., Tse, S., Tsin, C., Twachtman-Bassett, J., Twilt, M., Valcarcel, T., Valdovinos, R., Vallee, A., Van Mater, H., Vandenbergen, S., Vannoy, L., Varghese, C., Vasquez, N., Vega-Fernandez, P., Velez, J., Verbsky, J., Verstegen, R., von Scheven, E., Vora, S., Wagner-Weiner, L., Wahezi, D., Waite, H., Walker, B., Walters, H., Waterfield, M., Waters, A., Weiser, P., Weiss, P., Weiss, J., Wershba, E., Westheuser, V., White, A., Widrick, K., Williams, C., Wong, S., Woolnough, L., Wright, T., Wu, E., Yalcindag, A., Yasin, S., Yeung, R., Yomogida, K., Zeft, A., Zhang, Y., Zhao, Y., Zhu, A., Saper, Vivian E., Tian, Lu, Verstegen, Ruud H.J., Conrad, Carol K., Cidon, Michal, Hopper, Rachel K., Kuo, Christin S., Osoegawa, Kazutoyo, Baszis, Kevin, Bingham, Catherine A., Ferguson, Ian, Hahn, Timothy, Horne, Annacarin, Isupova, Eugenia A., Jones, Jordan T., Kasapcopur, Özgür, Klein-Gitelman, Marisa S., Kostik, Mikhail M., Ozen, Seza, Phadke, Omkar, Prahalad, Sampath, Randell, Rachel L., Sener, Seher, Stingl, Cory, Abdul-Aziz, Rabheh, Akoghlanian, Shoghik, Al Julandani, Dalila, Alvarez, Marcela B., Bader-Meunier, Brigitte, Balay-Dustrude, Erin E., Balboni, Imelda, Baxter, Sarah K., Berard, Roberta A., Bhattad, Sagar, Bolaria, Roxana, Boneparth, Alexis, Cassidy, Elaine A., Co, Dominic O., Collins, Kathleen P., Dancey, Paul, Dickinson, Aileen M., Edelheit, Barbara S., Espada, Graciela, Flanagan, Elaine R., Imundo, Lisa F., Jindal, Ankur K., Kim, Hyoun-Ah, Klaus, Günter, Lake, Carol, Lapin, W. Blaine, Lawson, Erica F., Marmor, Itay, Mombourquette, Joy, Ogunjimi, Benson, Olveda, Rebecca, Ombrello, Michael J., Onel, Karen, Poholek, Catherine, Ramanan, Athimalaipet V., Ravelli, Angelo, Reinhardt, Adam, Robinson, Amanda D., Rouster-Stevens, Kelly, Saad, Nadine, Schneider, Rayfel, Selmanovic, Velma, Sefic Pasic, Irmina, Shenoi, Susan, Shilo, Natalie R., Soep, Jennifer B., Sura, Angeli, Taber, Sarah F., Tesher, Melissa, Tibaldi, Jessica, Torok, Kathryn S., Tsin, Cathy Mei, Vasquez-Canizares, Natalia, Villacis Nunez, Diana S., Way, Emily E., Whitehead, Benjamin, Zemel, Lawrence S., Sharma, Surbhi, Fernández-Viña, Marcelo A., and Mellins, Elizabeth D.

Published
2024
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5. Pediatric mixed connective tissue disease versus other overlap syndromes: a retrospective multicenter cohort study

Author

Batu, Ezgi Deniz, Günalp, Aybüke, Şahin, Sezgin, Özdel, Semanur, Kızıldağ, Zehra, Pac Kısaarslan, Aysenur, Bağrul, İlknur, Kasap Cuceoglu, Muserref, Tanatar, Ayşe, Sonmez, Hafize Emine, Sag, Erdal, Demir, Selcan, Çelikel, Elif, Cağlayan, Sengul, Çelikel Acar, Banu, Sözeri, Betül, Aktay Ayaz, Nuray, Bilginer, Yelda, Poyrazoğlu, M. Hakan, Ünsal, Erbil, Kasapçopur, Özgür, and Özen, Seza

Published
2023
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9. Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: A multicenter study

Author

Kısaarslan, Ayşenur Paç, Çiçek, Sümeyra Özdemir, Batu, Ezgi D., Şahin, Sezgin, Gürgöze, Metin K., Çetinkaya, Sibel Balcı, Ekinci, Miray Kışla, Atmış, Bahriye, Barut, Kenan, Adrovic, Amra, Ağar, Buket Esen, Şahin, Nihal, Demir, Ferhat, Bağlan, Esra, Kara, Mehtap Akbalık, Selçuk, Şenay Zırhlı, Özdel, Semanur, Çomak, Elif, Akkoyunlu, Betül, Yener, Gülçin Otar, Yıldırım, Deniz Gezgin, Öztürk, Kübra, Yıldız, Mehmet, Haşlak, Fatih, Şener, Seher, Kısaoğlu, Hakan, Baba, Özge, Kızıldağ, Zehra, İşgüder, Rana, Çağlayan, Şengül, Bilgin, Raziye B. Güven, Aytaç, Gülçin, Yücel, Burcu Bozkaya, Tanatar, Ayşe, Sönmez, Hafize E., Çakan, Mustafa, Kara, Aslıhan, Elmas, Ahmet T., Kılıç, Beltinge Demircioğlu, Ayaz, Nuray Aktay, Kasap, Belde, Acar, Banu Çelikel, Ozkaya, Ozan, Yüksel, Selçuk, Bakkaloğlu, Sevcan, Aydoğ, Özlem, Aksu, Güzide, Akman, Sema, Dönmez, Osman, Bülbül, Mehmet, Büyükçelik, Mithat, Tabel, Yılmaz, Sözeri, Betül, Kalyoncu, Mukaddes, Bilginer, Yelda, Poyrazoğlu, Muammer H., Ünsal, Erbil, Kasapçopur, Özgür, Özen, Seza, and Düşünsel, Ruhan

Published
2023
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11. Differences and similarities of multisystem inflammatory syndrome in children, Kawasaki disease and macrophage activating syndrome due to systemic juvenile idiopathic arthritis: a comparative study

Author

Otar Yener, Gülçin, Paç Kısaarslan, Ayşenur, Ulu, Kadir, Atalay, Erdal, Haşlak, Fatih, Özdel, Semanur, Bozkaya Yücel, Burcu, Gezgin Yıldırım, Deniz, Çakmak, Figen, Öztürk, Kübra, Çakan, Mustafa, Balık, Zeynep, Hasbal Akkuş, Canan, Yıldız, Mehmet, Erat, Tuğba, Çetin, Benhur Şirvan, Yılmaz, Münevver, Bağlan, Esra, Laçinel Gürlevik, Sibel, Atasayan, Vildan, Karadağ, Şerife Gül, Adrovic, Amra, Çağlayan, Şengül, Tanatar, Ayşe, Demirkan, Fatma Gül, Coşkuner, Taner, Akgün, Özlem, Kasap Cüceoğlu, Müşerref, Kavrul Kayaalp, Gülşah, Şahin, Sezgin, Başaran, Özge, Demir, Ferhat, Barut, Kenan, Çiftel, Murat, Gürses, Dolunay, Baykan, Ali, Özsürekçi, Yasemin, Karagöz, Tevfik, Sönmez, Hafize Emine, Bilginer, Yelda, Aktay Ayaz, Nuray, Aydoğ, Özlem, Yüksel, Selçuk, Sözeri, Betül, Kasapçopur, Özgür, and Özen, Seza

Published
2022
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13. Childhood-onset systemic lupus erythematosus: A descriptive and comparative study of clinical, laboratory, and treatment characteristics in two populations.

Author

Kavrul Kayaalp, Gülşah, Esencan, Deren, Guliyeva, Vafa, Arık, Selen Duygu, Türkmen, Şeyma, Şahin, Sezgin, Bilginer, Yelda, Kasapçopur, Özgür, Sözeri, Betül, Özen, Seza, Aktay Ayaz, Nuray, and Sawalha, Amr H.

Subjects
TURKS, PEDIATRIC therapy, HEALTH policy, AGE of onset, DISEASE progression
Abstract

Objective: The aim of this study was to characterize childhood-onset systemic lupus erythematosus (SLE) in two large cohorts from Turkey and the United States. Methods: Patients diagnosed with childhood-onset SLE who fulfilled the 1997 American College of Rheumatology classification criteria for SLE from four reference centers in Turkey and the University of Pittsburgh School of Medicine in the United States were included in this study. A comparative analysis was conducted to evaluate the similarities and differences in clinical and laboratory features, damage accrual, and treatment experiences between the two populations. Results: A total of 174 patients with childhood-onset SLE were included in this study (108 patients from Turkey and 66 patients from the United States). The female-to-male ratio was similar between the two cohorts (∼3:1, p =.73). The median age at diagnosis was 11.67 years (2.19-17.93) in the Turkish cohort and 13.68 years (2.74-17.93) in the U.S. cohort (p <.001). Photosensitivity (45.4% and 21.2%; p =.007) and renal involvement (41.7% and 36.4%; p =.045) were higher in the Turkish cohort. Anti-Ro/SSA (34.8% and 15.7%; p <.001), anti-Sm (59.1% and 19.4%; p <.001), and anti-RNP (47.0% and 14.8%; p <.001) positivity was more frequent in the U.S. cohort. Current use of rituximab (37.9% and 1.9%; p <.001) and belimumab (19.7% and 0%; p <.001) was more prevalent in the U.S. cohort, while the use of cyclophosphamide (often according to the low dose Euro-Lupus protocol) throughout the disease course (24.1% and 4.5%; p <.001) was more frequent in the Turkish cohort. SLICC/ACR Damage Index scores were not different between the two cohorts. Conclusion: This study provides detailed clinical and laboratory features of childhood-onset SLE in two independent and geographically divergent cohorts. Our findings suggest an earlier age of disease onset and a higher prevalence of kidney involvement in Turkish patients. Differences in treatment approaches were also noted. However, damage accrual related to SLE does not appear to be different between the two patient populations. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Measuring Transition Readiness of Patients After Transfer from Pediatric to Adult Care in Rheumatology.

Author

Ayla, Ali Yağiz, Beşiroğlu, Helin İdil, Azman, Feyza Nur, Egeli, Buğra Han, Eren, Hatice, Öztürk, Sıla, Ergün, Sercan, Adrovic, Amra, Barut, Kenan, Haslak, Fatih, Şahin, Sezgin, Yıldız, Mehmet, Özdoğan, Huri, Kasapçopur, Özgür, and Ugurlu, Serdal

Subjects
RHEUMATISM treatment, CROSS-sectional method, SCALE analysis (Psychology), HEALTH status indicators, DIFFERENTIAL diagnosis, T-test (Statistics), QUESTIONNAIRES, KRUSKAL-Wallis Test, SEX distribution, CONTINUUM of care, RETROSPECTIVE studies, AUTOINFLAMMATORY diseases, DESCRIPTIVE statistics, MANN Whitney U Test, TRANSITIONAL care, PEDIATRICS, CONNECTIVE tissue diseases, ONE-way analysis of variance, MEDICAL records, ACQUISITION of data, ARTHRITIS, RHEUMATOLOGY, DATA analysis software, PATIENTS' attitudes, ADULTS
Abstract

Objective: Transitional care is essential to maintain the continuity of care in younger patients with rheumatic diseases. In this study, we aimed to assess the transition readiness of rheumatology patients who had already transferred from pediatric to adult care using a questionnaire. Materials and Methods: We included young adult rheumatology patients who had already transferred to adult rheumatology care. The Transition Readiness Assessment Questionnaire (TRAQ) was used in the adult rheumatology clinic to assess the patients’ readiness; a retrospective chart review was conducted to include diagnosis, age at diagnosis, age at transfer, and current age. Results: Three hundred and ten patients (184 female and 126 male) participated in this study. The mean age at diagnosis, the mean age at transfer, and the mean age at the time of the study were 10.7 ± 4.29, 21.1 ± 1.69, and 24.0 ± 2.26 years, respectively. Most of the patients had familial Mediterranean fever, followed by arthritis, connective tissue disorders, and other diseases. Tracking health issues was the lowest-scored domain. Females scored significantly higher than males in the tracking health issue domain (P = .006) and managing health issue domain (P = .028) but not in the overall TRAQ score (P = .053). Patients in different diagnosis and transfer age groups scored similarly across the domains. Conclusion: In this study, females performed better than males in 2 domains of the TRAQ questionnaire. Diagnoses or transfer age groups were not associated with TRAQ outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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16. COVID-19 vaccination rates and factors affecting vaccination in children with rheumatic disease

Author

Aydın, Tuncay, primary, Özomay Baykal, Gülcan, additional, Karagöl, Cüneyt, additional, Haşlak, Fatih, additional, Oğultekin Vazgeçer, Ebru, additional, Torun, Rüya, additional, Kızıldağ, Zehra, additional, Kılıç Könte, Elif, additional, Aslan, Esma, additional, Güngörer, Vildan, additional, Çelikel Acar, Banu, additional, Sözeri, Betül, additional, Kasapçopur, Özgür, additional, and Makay, Balahan, additional

Published
2024
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17. Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis on anti-interleukin-1 or -6 therapy

Author

Ulu, Kadir, primary, Aliyev, Emil, additional, Kılıç Könte, Elif, additional, Tanatar, Ayşe, additional, Türkmen, Şeyma, additional, Doğantan, Şeyda, additional, Kızıldağ, Zehra, additional, Kasap Demir, Belde, additional, Gezgin Yıldırım, Deniz, additional, Otar Yener, Gülçin, additional, Öztürk, Kübra, additional, Baba, Özge, additional, Açarı, Ceyhun, additional, Kılbaş, Gülşah, additional, Taşkın, Sema Nur, additional, Haşlak, Fatih, additional, Çağlayan, Şengül, additional, Bağlan, Esra, additional, Dundar, Hatice Adıgüzel, additional, Başaran, Özge, additional, Barut, Kenan, additional, Karadağ, Şerife Gül, additional, Coşkuner, Taner, additional, Sönmez, Hafize Emine, additional, Yüksel, Selçuk, additional, Kalyoncu, Mukaddes, additional, Bakkaloğlu, Sevcan A, additional, Ünsal, Erbil, additional, Paç Kısaarslan, Ayşenur, additional, Bilginer, Yelda, additional, Aktay Ayaz, Nuray, additional, Kasapçopur, Özgür, additional, Özen, Seza, additional, and Sözeri, Betül, additional

Published
2024
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18. Artificial Intelligence in Pediatrics: Learning to Walk Together.

Author

Demirbaş, Kaan Can, Yıldız, Mehmet, Saygılı, Seha, Canpolat, Nur, and Kasapçopur, Özgür

Subjects
GENOME editing, COMPUTER assisted instruction, ARTIFICIAL intelligence, PEDIATRICS, MACHINE learning, LEARNING strategies, ROBOTICS, RISK assessment, CHILD health services, EDUCATIONAL technology, DECISION making in clinical medicine, PREDICTION models, ALGORITHMS, EVALUATION
Abstract

In this era of rapidly advancing technology, artificial intelligence (AI) has emerged as a transformative force, even being called the Fourth Industrial Revolution, along with gene editing and robotics. While it has undoubtedly become an increasingly important part of our daily lives, it must be recognized that it is not an additional tool, but rather a complex concept that poses a variety of challenges. AI, with considerable potential, has found its place in both medical care and clinical research. Within the vast field of pediatrics, it stands out as a particularly promising advancement. As pediatricians, we are indeed witnessing the impactful integration of AI-based applications into our daily clinical practice and research efforts. These tools are being used for simple to more complex tasks such as diagnosing clinically challenging conditions, predicting disease outcomes, creating treatment plans, educating both patients and healthcare professionals, and generating accurate medical records or scientific papers. In conclusion, the multifaceted applications of AI in pediatrics will increase efficiency and improve the quality of healthcare and research. However, there are certain risks and threats accompanying this advancement including the biases that may contribute to health disparities and, inaccuracies. Therefore, it is crucial to recognize and address the technical, ethical, and legal challenges as well as explore the benefits in both clinical and research fields. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Clinical and histopathological prognostic factors affecting the renal outcomes in childhood ANCA-associated vasculitis

Author

Özçelik, Gül, Sönmez, Hafize Emine, Şahin, Sezgin, Özağarı, Ayşim, Bayram, Meral Torun, Çiçek, Rümeysa Yasemin, Çakıcı, Evrim Kargın, Çomak, Elif, Barut, Kenan, Şahin, Nihal, Bakkaloğlu, Sevcan, Gökçe, İbrahim, Düzova, Ali, Bilginer, Yelda, Açarı, Ceyhun, Melek, Engin, Kılıç, Beltinge Demircioğlu, Özdel, Semanur, Adroviç, Amra, Kasapçopur, Özgür, Ünsal, Erbil, Alpay, Harika, Orhan, Diclehan, Topaloğlu, Rezan, Düşünsel, Ruhan, and Özen, Seza

Published
2019
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22. Diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study

Author

Karacan, İlker, Balamir, Ayşe, Uğurlu, Serdal, Aydın, Aslı Kireçtepe, Everest, Elif, Zor, Seyit, Önen, Merve Özkılınç, Daşdemir, Selçuk, Özkaya, Ozan, Sözeri, Betül, Tufan, Abdurrahman, Yıldırım, Deniz Gezgin, Yüksel, Selçuk, Ayaz, Nuray Aktay, Ömeroğlu, Rukiye Eker, Öztürk, Kübra, Çakan, Mustafa, Söylemezoğlu, Oğuz, Şahin, Sezgin, Barut, Kenan, Adroviç, Amra, Seyahi, Emire, Özdoğan, Huri, Kasapçopur, Özgür, and Turanlı, Eda Tahir

Published
2019
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25. Temporary Thyroid Dysfunction and Catecholamine Excess Due to Mercury Poisoning in 6 Cases.

Author

Özer, Yavuz, Yıldız, Mehmet, Turan, Hande, Çakır, Aydilek Dağdeviren, Tarçın, Gürkan, Aydın, Dilek Bingöl, Bayramoğlu, Elvan, Haşlak, Fatih, Şahin, Sezgin, Adrovic, Amra, Barut, Kenan, Evliyaoğlu, Olcay, Kasapçopur, Özgür, and Ercan, Oya

Subjects
SODIUM metabolism, TACHYCARDIA diagnosis, MERCURY poisoning, PHYSICAL diagnosis, HYPERTENSION, BLOOD-brain barrier, THYROID diseases, CATECHOLAMINES, CHELATING agents, RETROSPECTIVE studies, EXANTHEMA, TREATMENT effectiveness, COMPARATIVE studies, HYPONATREMIA, DESCRIPTIVE statistics, PHEOCHROMOCYTOMA, DATA analysis software, THYROID antagonists, THYROID gland, EARLY diagnosis, DISEASE complications, CHILDREN
Abstract

Objective: Mercury poisoning is a condition with multiple-organ dysfunction that has effects on the central nervous system, gastrointestinal system, cardiovascular system, skin, lungs, and kidneys. It can be fatal or may result in sequelae such as neurological disturbances, if treated late or left untreated. The endocrinological effects of mercury exposure are not well-known. We aimed to evaluate patients with mercury poisoning. Materials and Methods: A total of 6 cases of mercury poisoning from 3 families were included in the study. Clinical, laboratory, and follow-up data were recorded. Results: Thyroid dysfunction was presented as high thyroid hormones and normal thyrotropin level (unsuppressed) in 5 cases (83.3%). On the other hand, pheochromocytoma-like syndrome was detected in 5 cases (83.3%) with hypertension. The 4 cases were the first to use methimazole for mercury poisoning due to tachycardia and hypertension despite antihypertensive treatment due to catecholamine excess and thyroid dysfunction. Hyponatremia was detected in 3 cases (50%). Conclusion: Mercury poisoning is difficult to diagnose because it is rare and presents with nonspecific physical and laboratory findings. Early diagnosis and providing appropriate treatment are essential in order to prevent sequelae. Mercury poisoning should be considered in patients with unexplained hypertension and tachycardia suggesting the involvement of thyroid hormones and catecholamines. [ABSTRACT FROM AUTHOR]

Published
2024
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26. A score for predicting colchicine resistance at the time of diagnosis in familial Mediterranean fever: data from the TURPAID registry

Author

Batu, Ezgi Deniz, primary, Şener, Seher, additional, Arslanoglu Aydin, Elif, additional, Aliyev, Emil, additional, Bagrul, İlknur, additional, Türkmen, Şeyma, additional, Akgün, Özlem, additional, Balık, Zeynep, additional, Tanatar, Ayşe, additional, Bayındır, Yağmur, additional, Kızıldağ, Zehra, additional, Torun, Rüya, additional, Günalp, Aybüke, additional, Coşkuner, Taner, additional, İşgüder, Rana, additional, Aydın, Tuncay, additional, Haşlak, Fatih, additional, Cüceoğlu, Müşerref Kasap, additional, Esen, Esra, additional, Akçay, Ulaş, additional, Başaran, Özge, additional, Kısaarslan, Aysenur Pac, additional, Akal, Fuat, additional, Yüce, Deniz, additional, Özdel, Semanur, additional, Bülbül, Mehmet, additional, Bilginer, Yelda, additional, Aktay Ayaz, Nuray, additional, Sözeri, Betül, additional, Kasapçopur, Özgür, additional, Ünsal, Erbil, additional, and Özen, Seza, additional

Published
2023
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28. A score for predicting colchicine resistance at the time of diagnosis in familial Mediterranean fever: data from the TURPAID registry

Author

Özdel, Semanur, Aliyev, Emil, Bagrul, İlknur, Türkmen, Şeyma, Akgün, Özlem, Balık, Zeynep, Tanatar, Ayşe, Bayındır, Yağmur, Kızıldağ, Zehra, Torun, Rüya, Günalp, Aybüke, Coşkuner, Taner, İşgüder, Rana, Aydın, TUNCAY, Haşlak, Fatih, Cüceoğlu, Müşerref Kasap, Esen, Esra, Akçay, Ulaş, Başaran, Özge, Kısaarslan, Aysenur Pac, Akal, Fuat, Yüce, Deniz, Arslanoglu Aydin, Elif, Bülbül, Mehmet, Bilginer, Yelda, Aktay Ayaz, Nuray, Sözeri, Betül, Kasapçopur, Özgür, Ünsal, Erbil, Özen, Seza, Batu, Ezgi Deniz, and Şener, Seher

Subjects
Rheumatology, Pharmacology (medical)
Abstract

Objectives Colchicine forms the mainstay of treatment in familial Mediterranean fever (FMF). Around 5–10% of FMF patients are colchicine resistant and require anti-interleukin-1 drugs. We aimed to compare the characteristics of colchicine-resistant and colchicine-responsive patients and to develop a score for predicting colchicine resistance at the time of FMF diagnosis. Methods FMF patients (0–18 years) enrolled in the TURPAID (Turkish Pediatric Autoinflammatory Diseases) registry were included. The predictive score for colchicine resistance was developed by using univariate/multivariate regression and ROC analyses. Results A total of 3445 FMF patients (256 [7.4%] colchicine-resistant and 3189 colchicine-responsive) were included (F/M = 1.02; median age at diagnosis 67.4 months). Colchicine-resistant patients had longer, more frequent attacks and were younger at symptom onset and diagnosis (p< 0.05). Fever, erysipelas-like erythema, arthralgia, arthritis, myalgia, abdominal pain, diarrhea, chest pain, comorbidities, parental consanguinity, and homozygosity/compound heterozygosity for exon 10 MEFV mutations were significantly more prevalent among colchicine-resistant than colchicine-responsive patients (p< 0.05). Multivariate logistic regression analysis in the training cohort (n = 2684) showed that age at symptom onset, attack frequency, arthritis, chest pain, and having two exon 10 mutations were the strongest predictors of colchicine resistance. The score including these items had a sensitivity of 81.3% and a specificity of 49.1%. In the validation cohort (n = 671), its sensitivity was 93.5% and specificity was 53.8%. Conclusion We have developed a clinician-friendly and practical predictive score which could help us to identify FMF patients with a greater risk of colchicine resistance and tailor disease management individually at the time of diagnosis.

Published
2023

29. Welcome to the New Issue (Vol: 29, No: 3, 2023) and Current News of the European Journal of Therapeutics.

Author

Balat, Ayşe, Eren, Şevki Hakan, Menzilcioğlu, Mehmet Sait, Bahşi, İlhan, Doğan, İlkay, Acıduman, Ahmet, Çiğ, Bilal, Georgiev, Tsvetoslav, Grillo, Ricardo, Govsa, Figen, Kaplan, Davut Sinan, Karadağ, Mehmet, Karaoğlan, Murat, Kasapçopur, Özgür, Naqvi, Waqar M., Nasimi, Ali, Nedzvetsky, Victor, Olszewski, Raphael, Ostrowski, Janusz, and Özçelik, Ayşe Aysima

Published
2023
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30. Risk factors for coronary arterial involvement in Turkish children with Kawasaki disease: a multicenter retrospective study

Author

Türkuçar, Serkan, primary, Özen, Seza, additional, Ünal, Nurettin, additional, Karagöz, Tevfik, additional, Kasapçopur, Özgür, additional, Sözeri, Betül, additional, Ayaz, Nuray Aktay, additional, Bilginer, Yelda, additional, Makay, Balahan, additional, Karabulut, Erdem, additional, Demir, Ferhat, additional, Haşlak, Fatih, additional, Çakmak, Figen, additional, Kaya, Ümmüşen Akça, additional, and Ünsal, Erbil, additional

Published
2023
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31. Evaluation of clinical outcomes in systemic juvenile idiopathic arthritis patients treated with biological agents in Turkey: the TURSIS study

Author

Sözeri, Betül, primary, Demir, Ferhat, additional, Barut, Kenan, additional, Atalay, Erdal, additional, Pac Kisaarslan, Ayşenur, additional, Özdel, Semanur, additional, Altuğ Gücenmez, Özge, additional, Makay, Balahan, additional, Aktay Ayaz, Nuray, additional, Haşlak, Fatih, additional, Sağ, Erdal, additional, Yıldız, Mehmet, additional, Kaya Akça, Ümmüşen, additional, Adroviç, Amra, additional, Bilginer, Yelda, additional, Poyrazoğlu, Hakan, additional, Ünsal, Erbil, additional, Kasapçopur, Özgür, additional, and Özen, Seza, additional

Published
2023
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32. Monitoring of Antibody Levels Following SARS-CoV-2 Infection in Children and Late Adolescents with Inflammatory Rheumatic Diseases

Author

Haşlak, Fatih, primary, Özbey, Doğukan, additional, Yıldız, Mehmet, additional, Yıldız, Amra Adrovic, additional, Şahin, Sezgin, additional, Köker, Oya, additional, Aliyeva, Ayten, additional, Guliyeva, Vafa, additional, Yalçın, Gamze, additional, İnanlı, Gülmelek, additional, Kocazeybek, Bekir Sami, additional, Kasapçopur, Özgür, additional, and Barut, Kenan, additional

Published
2022
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33. Children and Peace.

Author

Kasapçopur, Özgür

Subjects
*DREAMS, *EMPATHY, *PEDIATRICIANS, *WAR, *EMOTIONS, *VIOLENCE in the community, *SOCIAL change, *HUMAN rights, *QUALITY of life, *PHYSICIAN-patient relations, *SOCIAL values, *PSYCHOSOCIAL factors, *FRIENDSHIP
Published
2024
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35. Child Brides and Forced Marriages: An Aspect of Child Abuse and Neglect

Author

Pettoello-Mantovani, Massimo, primary, Cokugras, Haluk, additional, Ferrara, Pietro, additional, Indrio, Flavia, additional, Giardino, Ida, additional, Canpolat, Nur, additional, Kasapçopur, Özgür, additional, Zeybek, Ayse Cigdem, additional, Beser, Omer Faruk, additional, Pettoello-Mantovani, Clara, additional, and Cokugras, Fugen Cullu, additional

Published
2022
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36. The impact of COVID-19 on clinical course and treatment among patients with juvenile systemic sclerosis.

Author

Adrovic, Amra, Yıldız, Mehmet, Haşlak, Fatih, Şahin, Sezgin, Köker, Oya, Günalp, Aybüke, Barut, Kenan, and Kasapçopur, Özgür

Subjects
PATIENT aftercare, CLINICAL deterioration, HEALTH services accessibility, COVID-19, CROSS-sectional method, APPLICATION software, SYSTEMIC scleroderma, FAMILIES, SURVEYS, DESCRIPTIVE statistics, HOSPITAL care, COVID-19 pandemic, WORLD Wide Web, TELEMEDICINE, SYMPTOMS
Abstract

Objectives: This study aimed to explore the influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic among patients with juvenile systemic sclerosis (JSS). Patients and methods: Twenty-seven patients (22 females, 5 males; mean age: 20 years; range, 17 to 22 years) diagnosed with JSS and followed up at the department of pediatric rheumatology were included in the cross-sectional study. A web-based survey was performed by focusing on patients' complaints, accessibility to health care, and compliance with routine treatment from January 1, 2021, to January 10, 2021. Results: Five (18.5%) patients had deterioration of the disease, while six (22.2%) patients reported irregular usage of their routine scleroderma treatment during the last six months. Nine (33.3%) patients had missed their routine clinic control since the proclamation of the SARS-CoV-2 pandemic. Seven (25.9%) patients had household contact with coronavirus disease 2019 (COVID-19). Four (14.8%) patients were diagnosed with COVID-19, and only one (3.7%) was hospitalized. Nine patients were under biological treatment (tocilizumab); however, only one of them was diagnosed with COVID-19. Conclusion: The COVID-19 pandemic has not significantly disrupted the medical care of JSS patients. Telemedicine could be an acceptable option for JSS patients disenabled to come to the hospital. [ABSTRACT FROM AUTHOR]

Published
2023
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39. Number of Episodes Can Be Used as a Disease Activity Measure in Familial Mediterranean Fever

Author

Demirkaya, Erkan, Speechley, Kathy, Laxer, Ronald M., KASAPÇOPUR, Özgür, Poyrazoglu, Hakan, Berard, Roberta A., BİLGİNER, YELDA, Ayaz, Nuray, MAKAY, BALAHAN, Romano, Micol, Konukbay, Dilek, Arici, Zehra Serap, and Piskin, David

Subjects
Pediatrics, Perinatology and Child Health
Abstract

ObjectiveTo evaluate the number of episodes in the past 12 months as an indicator of the overall disease activity status in Familial Mediterranean fever (FMF).MethodsIn this cross-sectional study, patients were recruited from tertiary pediatric hospitals. Demographic data, main clinical symptoms of the episodes, treatment modalities, and genetic mutations were recorded. The patients were grouped as no episodes (Group 1), 1–4 episodes (Group 2), and more than 4 episodes (Group 3) according to the number of episodes in the past 12 months. The Pediatric Quality Life Inventory (PedsQL), the Children’s Depression Inventory (CDI), and the Wong-Baker FACES Pain Rating Scale (FACES) scores were compared between groups. Concurrent validity between the number of episodes and the patient-reported outcome measures (PROMs) was assessed using Spearman’s rank correlation coefficient (ρ).ResultsA total of 239 patients were included. There were 74 patients (31%) in Group 1, 99 (41.4%) in Group 2, and 66 (27.6%) in Group 3. Groups were similar according to age, age at diagnosis, gender, consanguinity, family history, history of amyloidosis, clinical symptoms, and in terms of allele frequency (p > 0.05). According to PROMs completed by parents, moderate correlations were found between the number of episodes and the PedsQL score (ρ = −0.48; 95% CI = −0.58 to −0.35, p < 0.001) and between the number of episodes and the Wong-Baker FACES score (ρ = 0.47, 95% CI = 0.35–0.57, p < 0.001).ConclusionThe number of episodes was positively and moderately correlated with patient- and parent-reported outcomes in our cohort. The number of episodes in patients with FMF can be used as a single measure to assess disease activity.

Published
2022

40. Non-Rheumatic Chronic Comorbidities in Children with Juvenile Idiopathic Arthritis.

Author

Haşlak, Fatih, Guliyeva, Vafa, Hotaman, Büşra, Duman, Çisem, Yıldız, Mehmet, Günalp, Aybüke, Aslan, Esma, Könte, Elif Kılıç, Aliyeva, Ayten, Adrovic, Amra, Şahin, Sezgin, Barut, Kenan, and Kasapçopur, Özgür

Subjects
CHRONIC disease risk factors, COMORBIDITY, RISK factors of attention-deficit hyperactivity disorder, AUTOANTIBODIES, CROSS-sectional method, JUVENILE idiopathic arthritis, ACQUISITION of data, INTERVIEWING, RHINITIS, RETROSPECTIVE studies, AUTOIMMUNE diseases, RISK assessment, ANTIRHEUMATIC agents, MEDICAL records, ATOPIC dermatitis, DISEASE risk factors, DISEASE complications, CHILDREN
Abstract

Objective: Juvenile idiopathic arthritis is a heterogeneous group of disorders and is the most common rheumatic condition in childhood. There are scarce data regarding all comorbidities in juvenile idiopathic arthritis patients. Materials and Methods: We aimed to identify the non-rheumatic comorbidities in our juvenile idiopathic arthritis patients. Data were obtained cross-sectionally from the medical records and the face-to-face interviews for 6 consecutive months. Those with more than 1 rheumatic disease were excluded, and conditions that were highly related to the disease, such as uveitis, were not taken into account. Results: The study included 459 patients with female dominance (62.1%, n = 285). The median age of the patients was 12.87 (1.53-20.95) years. One hundred fifty patients (32.7%) had at least 1 comorbidity (5 patients had 3 comorbidities, and 24 patients had 2 comorbidities). The most common 3 non-rheumatic accompanying medical conditions in our patients were allergic rhinitis (n = 37, 8.1%), attention-deficit hyperactivity disorder (n = 35, 7.6%), and atopic dermatitis (n = 28, 6.1%). None of our patients with systemic JIA had any autoimmune disease. All the patients with primary immune deficiencies had anti-nuclear antibody positivity. Conclusion: Almost one-third of our patients had at least one comorbidity. This finding might be very helpful to us in planning our multi-disciplinary approach to our patients. [ABSTRACT FROM AUTHOR]

Published
2023
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42. Correction to: Diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study

Author

Karacan, İlker, Balamir, Ayşe, Uğurlu, Serdal, Aydın, Aslı Kireçtepe, Everest, Elif, Zor, Seyit, Önen, Merve Özkılınç, Daşdemir, Selçuk, Özkaya, Ozan, Sözeri, Betül, Tufan, Abdurrahman, Yıldırım, Deniz Gezgin, Yüksel, Selçuk, Ayaz, Nuray Aktay, Ömeroğlu, Rukiye Eker, Öztürk, Kübra, Çakan, Mustafa, Söylemezoğlu, Oğuz, Şahin, Sezgin, Barut, Kenan, Adroviç, Amra, Seyahi, Emire, Özdoğan, Huri, Kasapçopur, Özgür, and Turanlı, Eda Tahir

Published
2019
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44. Risk factors for coronary arterial involvement in turkish children with kawasaki disease: a multicenter retrospective study

Author

Kasapçopur, Özgür, Ünsal, Erbil, Özen, Seza, Ünal, Nurettin, Karagöz, Tevfik, Sözeri, Betül, Ayaz, Nuray Aktay, BİLGİNER, YELDA, MAKAY, BALAHAN, KARABULUT, ERDEM, Demir, Ferhat, Haşlak, Fatih, ÇAKMAK, Figen, Kaya, Ümmüşen Akça, and TÜRKUÇAR, SERKAN

Subjects
Pediatrics, Perinatology and Child Health
Abstract

Background. Coronary arterial lesions (CALs) are the major component of Kawasaki disease (KD), associated with significant morbidity, which affect a substantial proportion of patients despite proper treatment. The aim of this study was to define the risk factors for CALs in Turkish children with KD. Methods. Medical records of 399 KD patients from five pediatric rheumatology centers in Turkey were reviewed retrospectively. Demographic, clinical (including duration of fever before intravenous immunoglobulin [IVIG] and resistance to IVIG), laboratory and echocardiographic data were noted. Results. The patients with CALs were younger, had a higher male ratio and a longer duration of fever before IVIG. They also had higher lymphocyte and lower hemoglobin values before the initial treatment. Multiple logistic regression analyses defined the following three criteria as independent risk factors for predicting CALs in Turkish children with KD: age ≤12 months, male gender and duration of fever before IVIG ≥9.5 days. High sensitivity rates of elevated risk of CALs up to 94.5% were calculated despite specificity values falling to 16.5%, depending on which of these three parameters are taken into account. Conclusions. Based on the demographic and clinical features, we established an easily applicable risk-scoring system for predicting CALs in Turkish children with KD. This may be useful for choosing appropriate treatment and follow-up for KD to prevent coronary artery involvement. Further studies will show whether these risk factors can be used in other Caucasian populations as well.

Published
2023

46. A case of juvenile systemic sclerosis and congenital pulmonary airway malformation related mucinous adenocarcinoma of the lung: paraneoplastic syndrome or just a coincidence?

Author

Aliyeva, Ayten, primary, Adrovic, Amra, additional, Ocak, Süheyla, additional, Batur, Şebnem, additional, Yıldız, Mehmet, additional, Haşlak, Fatih, additional, Köker, Oya, additional, Şahin, Sezgin, additional, Barut, Kenan, additional, and Kasapçopur, Özgür, additional

Published
2022
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50. A fatal interstitial lung disease in an anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody negative patient with juvenile dermatomyositis

Author

Yeşilbaş, Osman, primary, Barut, Kenan, additional, Şahin, Sezgin, additional, Adrovic, Amra, additional, Çakır, Erkan, additional, Yazan, Hakan, additional, Tahaoğlu, Irmak, additional, Yozgat, Can Yılmaz, additional, Yıldız, Mehmet, additional, and Kasapçopur, Özgür, additional

Published
2021
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