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1,178 results on '"Kassubek, J"'

2. Die neue Parkinson-Schmerzklassifikation (PSK)

Author

Mylius, V., Perez Lloret, S., Brook, C. S., Krüger, M. T., Hägele-Link, S., Gonzenbach, R., Kassubek, J., Bohlhalter, S., Lefaucheur, J. P., Timmermann, L., Kägi, G., Brugger, F., Ciampi de Andrade, D., and Möller, J. C.

Published
2022
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4. Severity dependent distribution of impairments in PSP and CBS: Interactive visualizations

Author

Williams, David, Lafontaine, Anne Louise, Marras, Connie, Jog, Mandar, Panisset, Michael, Lang, Anthony, Parker, Lesley, Stewart, Alistair J., Corvol, Jean-Christophe, Azulay, Jean-Philippe, Couratier, Philippe, Mollenhauer, Brit, Lorenzl, Stefan, Ludolph, Albert, Benecke, Reiner, Hoglinger, Gunter, Lipp, Axel, Reichmann, Heinz, Woitalla, Dirk, Chan, Dennis, Zermansky, Adam, Burn, David, Lees, Andrew, Gozes, Illana, Boxer, Adam, Miller, Bruce L., Lobach, Iryna V., Roberson, Erik, Honig, Lawrence, Zamrini, Edward, Pahwa, Rajesh, Bordelon, Yvette, Driver-Dunkley, Erika, Lessig, Stephanie, Lew, Mark, Womack, Kyle, Boeve, Brad, Ferrara, Joseph, Hillis, Argyle, Kaufer, Daniel, Kumar, Rajeev, Xie, Tao, Gunzler, Steven, Zesiewicz, Theresa, Dayalu, Praveen, Golbe, Lawrence, Grossman, Murray, Jankovic, Joseph, McGinnis, Scott, Santiago, Anthony, Tuite, Paul, Isaacson, Stuart, Leegwater-Kim, Julie, Litvan, Irene, Knopman, David S., Schneider, Lon S., Doody, Rachelle S., Golbe, Lawrence I., Roberson, Erik D., Koestler, Mary, Jack, Clifford R., Jr., Van Deerlin, Viviana, Randolph, Christopher, Whitaker, Steve, Hirman, Joe, Gold, Michael, Morimoto, Bruce H., Nuebling G, Georg, Hensler, Mira, Paul, Sabine, Zwergal, Andreas, Heuer, Hilary W., Tartaglia, Maria C., McGinnis, Scott M., Dickerson, Bradford C., Kornak, John, Schuff, Norbert, Rabinovici, Gil D., Rosen, Howard J., Boxer, Adam L., Gómez, J.C., Tijero, B., Berganzo, K., Garc'ıa de Yebenes, J., Lopez Sendón, J.L., Garcia, G., Tolosa, E., Buongiorno, M.T., Bargalló, N., Burguera, J.A., Martinez, I., Ruiz-Mart'ınez, J., Narrativel, I., Vivancos, F., Ybot, I., Aguilar, M., Quilez, P., Boada, M., Lafuente, A., Hernandez, I., López-Lozano, J.J., Mata, M., Kupsch, A., Lipp, A., Ebersbach, G., Schmidt, T., Hahn, K., Höglinger, G., Höllerhage, M., Oertel, W.H., Respondek, G., Stamelou, M., Reichmann, H., Wolz, M., Schneider, C., Klingelhöfer, L., Berg, D., Maetzler, W., Srulijes, K.K., Ludolph, A., Kassubek, J., Steiger, M., Tyler, K., Burn, D.J., Morris, L., Lees, A., Ling, H., Hauser, R., McClain, T., Truong, D., Jenkins, S., Litvan, I., Houghton, D., Ferrara, J., Bordelon, Y., Gratiano, A., Golbe, L., Mark, M., Uitti, R., Ven Gerpen, J., Brittain, Claire, McCarthy, Andrew, Irizarry, Michael C., McDermott, Dana, Biglan, Kevin, Höglinger, Günter U., and del Ser, Teodoro

Published
2019
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21. The Contribution of White and Gray Matter Differences to Developmental Dyslexia: Insights from DTI and VBM at 3.0 T

Author

Steinbrink, C., Vogt, K., Kastrup, A., Muller, H. P., Juengling, F. D., Kassubek, J., and Riecker, A.

Abstract

Developmental dyslexia is one of the most common neuropsychological disorders in children and adults. Only few data are available on the pathomechanisms of this specific dysfunction, assuming--among others--that dyslexia might be a disconnection syndrome of anterior and posterior brain regions involved in phonological and orthographic aspects of the reading process, as well as in the integration of phonemes and graphemes. Therefore, diffusion tensor imaging (DTI) and voxel-based morphometry (VBM) were used to verify the hypothesis of altered white and gray matter structure in German dyslexic adults. DTI revealed decreased fractional anisotropy (FA) in bilateral fronto-temporal and left temporo-parietal white matter regions (inferior and superior longitudinal fasciculus). Significant correlations between white matter anisotropy and speed of pseudoword reading were found. In dyslexics, gray matter volumes (as measured by VBM) were reduced in the superior temporal gyrus of both hemispheres. So far, our results, based on a combined analysis of white and gray matter abnormalities, provide exceedingly strong evidence for a disconnection syndrome or dysfunction of cortical areas relevant for reading and spelling. Thus, we suggest that this imbalance of neuronal communication between the respective brain areas might be the crucial point for the development of dyslexia. (Contains 2 tables and 2 figures.)

Published
2008
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25. Theme 11 - Cognitive and Psychological Assessment and Support.

Author

de Moree, S., Lule, D., Michels, S., Finsel, J., Braak, H., Del Tredici, K., Strobel, J., Beer, A., Uttner, I., Müller, H., Kassubek, J., Juengling, F., Ludolph, A., McMackin, R., Plaitano, S., Metzger, M., Sirenko, V., Giglia, E., Mehra, P., and Tadjine, Y.

Subjects
PSYCHOLOGICAL tests, AMYOTROPHIC lateral sclerosis, ALZHEIMER'S disease, APATHY, ETHNIC differences
Abstract

2006; 16 (7): 916 - 28. 16 Radakovic R, Abrahams S. Developing a new apathy measurement scale: Dimensional Apathy Scale, Psychiatry Res. 2014; 219 (3): 658 - 63. 17 Huynh W, Ahmed R, Mahoney CJ, et al. Measurement of Social Cognition in Amyotrophic Lateral Sclerosis: A Population Based Study. 7 Girardi A, MacPherson SE, Abrahams S, Deficits in emotional and social cognition in amyotrophic lateral sclerosis, Neuropsychology. [Extracted from the article]

Published
2022
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36. SPG10 is a rare cause of spastic paraplegia in European families

Author

Schule, R., Kremer, B.P.H., Kassubek, J., Auer-Grumbach, M., Kostic, V., Klopstock, T., Klimpe, S., Otto, S., Boesch, S., van de Warrenburg, B.P., and Schols, L.

Subjects
Paralysis, Spastic -- Causes of, Paralysis, Spastic -- Demographic aspects, Paralysis, Spastic -- Genetic aspects, Gene mutations -- Research, Gene mutations -- Physiological aspects, Health, Psychology and mental health
Published
2008

40. Quality of life in a German cohort of Parkinson’s patients assessed with three different measures

Author

Balzer-Geldsetzer, M., Klotsche, J., Reetz, K., Spottke, A., Storch, A., Baudrexel, S., Mollenhauer, B., Berg, D., Liepelt, I., Kassubek, J., Kalbe, E., Wittchen, H.U., Dodel, R., and Riedel, O.

Subjects
Male, medicine.medical_specialty, Parkinson's disease, Medizin, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Germany, Surveys and Questionnaires, Humans, Medicine, Prospective Studies, 030212 general & internal medicine, Prospective cohort study, Depression (differential diagnoses), Aged, business.industry, Parkinson Disease, Middle Aged, medicine.disease, Comorbidity, humanities, Neurology, Cohort, Quality of Life, Physical therapy, Female, Cohort study, WHOQOL-100, DEMPARK/LANDSCAPE study, Parkinson’s disease, Geriatric Depression Scale, Neurology (clinical), business, human activities, 030217 neurology & neurosurgery
Abstract

BACKGROUND: Parkinson’s disease (PD) is characterized by severe motor and non-motor symptoms reducing patients’ quality of life (QoL). Instruments have been well established for QoL assessments in PD, including the EuroQol (EQ-5D), the Parkinson’s disease questionnaire (PDQ-39), or rather uncommon, like the WHOQOL-100. So far, the impact of variables has been investigated for each of these measures separately in different study populations, limiting the comparability of the results. Thus, this study compared the EQ-5D, PDQ-39, and the WHOQOL-100 (with its short-form WHOQOL-BREF) in the same study population. METHODS: Seventy-five PD outpatients were assessed in a prospective study, including disease severity according to Hoehn and Yahr stage (HY) and Unified Parkinson Disease Rating Scale (UPDRS). The Geriatric Depression Scale (GDS-15) screened for depression. RESULTS: Decreased QoL was found with all three instruments. In multivariate models, sex and treatment complications had an impact on QoL according to all three measures, while duration of PD and HY was not associated with QoL in any of them. Depression was relevant for the WHOQOL-100/WHOQOL-BREF and the PDQ-39, but not for the EQ-5D. The total variances explained by the WHOQOL-100, WHOQOL-BREF, PDQ-39, and the EQ-5D were 0.27, 0.34, 0.70, and 0.50, respectively. CONCLUSIONS: The associations between clinical aspects of PD and QoL vary substantially among all three measures. Importantly, depression as a frequent comorbidity in PD is underestimated by the EQ-5D, but not by the PDQ-39 and the WHOQOL-100/WHOQOL-BREF. In turn, motor impairments are underestimated by the latter and associated strongest with QoL in the EQ-5D.

Published
2018

44. Topography of cerebral atrophy in early Huntington's disease: a voxel based morphometric MRI study

Author

Kassubek, J., Juengling, F.D., Kioschies, T., Henkel, K., Karitzky, J., Kramer, B., Ecker, D., Andrich, J., Saft, C., Kraus, P., Aschoff, A.J., Ludolph, A.C., and Landwehrmeyer, G.B.

Subjects
Huntington's chorea -- Research -- Diagnosis -- Physiological aspects, Health, Psychology and mental health, Diagnosis, Physiological aspects, Research
Abstract

J Neurol Neurosurg Psychiatry 2004;75:213-220 Objectives: To analyse grey matter changes in early stages of Huntington's disease using magnetic resonance imaging (MRI) and the technique of voxel based morphometry (VBM). [...]

Published
2004

45. Neuroimaging in the Management of Motor Neuron Diseases

Author

Filippi, M., primary, Agosta, F., additional, Abrahams, S., additional, Fazekas, F., additional, Grosskreutz, J., additional, Kalra, S., additional, Kassubek, J., additional, Silani, V., additional, Turner, M. R., additional, and Masdeu, J. C., additional

Published
2011
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