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415 results on '"Kasten, M."'

1. Muon (g-2) Technical Design Report

Author: Grange, J., Guarino, V., Winter, P., Wood, K., Zhao, H., Carey, R. M., Gastler, D., Hazen, E., Kinnaird, N., Miller, J. P., Mott, J., Roberts, B. L., Benante, J., Crnkovic, J., Morse, W. M., Sayed, H., Tishchenko, V., Druzhinin, V. P., Khazin, B. I., Koop, I. A., Logashenko, I., Shatunov, Y. M., Solodov, E., Korostelev, M., Newton, D., Wolski, A., Chapelain, A., Bjorkquist, R., Eggert, N., Frankenthal, A., Gibbons, L., Kim, S., Mikhailichenko, A., Orlov, Y., Rubin, D., Sweigart, D., Allspach, D., Annala, G., Barzi, E., Bourland, K., Brown, G., Casey, B. C. K., Chappa, S., Convery, M. E., Drendel, B., Friedsam, H., Gadfort, T., Hardin, K., Hawke, S., Hayes, S., Jaskierny, W., Johnstone, C., Johnstone, J., Kashikhin, V., Kendziora, C., Kiburg, B., Klebaner, A., Kourbanis, I., Kyle, J., Larson, N., Leveling, A., Lyon, A. L., Markley, D., McArthur, D., Merritt, K. W., Mokhov, N., Morgan, J. P., Nguyen, H., Ostiguy, J-F., Para, A., Popovic, C. C. Polly M., Ramberg, E., Rominsky, M., Schoo, D., Schultz, R., Still, D., Soha, A. K., Strigonov, S., Tassotto, G., Turrioni, D., Villegas, E., Voirin, E., Velev, G., Welty-Rieger, L., Wolff, D., Worel, C., Wu, J-Y., Zifko, R., Jungmann, K., Onderwater, C. J. G., Debevec, P. T., Ganguly, S., Kasten, M., Leo, S., Pitts, K., Schlesier, C., Gaisser, M., Haciomeroglu, S., Kim, Y-I., Lee, S., Lee, M-J, Semertzidis, Y. K., Giovanetti, K., Baranov, V. A., Duginov, V. N., Khomutov, N. V., Krylov, V. A., Kuchinskiy, N. A., Volnykh, V. P., Crawford, C., Fatemi, R., Gohn, W. P., Gorringe, T. P., Korsch, W., Plaster, B., Anastasi, A., Babusci, D., Dabagov, S., Ferrari, C., Fioretti, A., Gabbanini, C., Hampai, D., Palladino, A., Venanzoni, G., Bowcock, T., Carroll, J., King, B., Maxfield, S., McCormick, K., Price, J., Sim, D., Smith, A., Teubner, T., Turner, W., Whitley, M., Wormald, M., Chislett, R., Kilani, S., Lancaster, M., Motuk, E., Stuttard, T., Warren, M., Flay, D., Kawall, D., Meadows, Z., Chupp, T., Raymond, R., Tewlsey-Booth, A., Syphers, M. J., Tarazona, D., Catalonotti, S., Di Stefano, R., Iacovacci, M., Mastroianni, S., Chattopadhyay, S., Eads, M., Fortner, M., Hedin, D., Pohlman, N., de Gouvea, A., Schellman, H., Azfar, F., Henry, S., Alkhazov, G. D., Golovtsov, V. L., Neustroev, P. V., Uvarov, L. N., Vasilyev, A. A., Vorobyov, A. A., Zhalov, M. B., Cerrito, L., Gray, F., Di Sciascio, G., Moricciani, D., Fu, C., Ji, X., Li, L., Yang, H., Stöckinger, D., Cantatore, G., Cauz, D., Karuza, M., Pauletta, G., Santi, L., Baeßler, S., Bychkov, M., Frlez, E., Pocanic, D., Alonzi, L. P., Fertl, M., Fienberg, A., Froemming, N., Garcia, A., Kaspar, D. W. Hertzog J., Kammel, P., Osofsky, R., Smith, M., Swanson, E., van Wechel, T., and Lynch, K.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: The Muon (g-2) Experiment, E989 at Fermilab, will measure the muon anomalous magnetic moment a factor-of-four more precisely than was done in E821 at the Brookhaven National Laboratory AGS. The E821 result appears to be greater than the Standard-Model prediction by more than three standard deviations. When combined with expected improvement in the Standard-Model hadronic contributions, E989 should be able to determine definitively whether or not the E821 result is evidence for physics beyond the Standard Model. After a review of the physics motivation and the basic technique, which will use the muon storage ring built at BNL and now relocated to Fermilab, the design of the new experiment is presented. This document was created in partial fulfillment of the requirements necessary to obtain DOE CD-2/3 approval., Comment: 666 pages
Published: 2015

2. Urodynamics: Imposition or not as bad as it seems? Secondary analyses from a randomized controlled trial

Author: Gross, O., primary, Kasten, M., additional, Wettstein, M., additional, Anderson, C.E., additional, Birkhäuser, V., additional, Borer, J., additional, Koschorke, M., additional, Liechti, M.D., additional, Mccallin, S., additional, Mehnert, U., additional, Röthlisberger, R., additional, Sadri, H., additional, Stächele, L., additional, Van Der Lely, S., additional, Kessler, T.M., additional, and Leitner, L., additional
Published: 2024
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3. Narcoleptic and Schizophrenic Hallucinations: Implications for Differential Diagnosis and Pathophysiology

Author: Dahmen, N., Kasten, M., Mittag, K., and Müller, M. J.
Published: 2002

4. Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort

Author: Vollstedt, E.-J. Schaake, S. Lohmann, K. Padmanabhan, S. Brice, A. Lesage, S. Tesson, C. Vidailhet, M. Wurster, I. Hentati, F. Mirelman, A. Giladi, N. Marder, K. Waters, C. Fahn, S. Kasten, M. Brüggemann, N. Borsche, M. Foroud, T. Tolosa, E. Garrido, A. Annesi, G. Gagliardi, M. Bozi, M. Stefanis, L. Ferreira, J.J. Correia Guedes, L. Avenali, M. Petrucci, S. Clark, L. Fedotova, E.Y. Abramycheva, N.Y. Alvarez, V. Menéndez-González, M. Jesús Maestre, S. Gómez-Garre, P. Mir, P. Belin, A.C. Ran, C. Lin, C.-H. Kuo, M.-C. Crosiers, D. Wszolek, Z.K. Ross, O.A. Jankovic, J. Nishioka, K. Funayama, M. Clarimon, J. Williams-Gray, C.H. Camacho, M. Cornejo-Olivas, M. Torres-Ramirez, L. Wu, Y.-R. Lee-Chen, G.-J. Morgadinho, A. Pulkes, T. Termsarasab, P. Berg, D. Kuhlenbäumer, G. Kühn, A.A. Borngräber, F. de Michele, G. De Rosa, A. Zimprich, A. Puschmann, A. Mellick, G.D. Dorszewska, J. Carr, J. Ferese, R. Gambardella, S. Chase, B. Markopoulou, K. Satake, W. Toda, T. Rossi, M. Merello, M. Lynch, T. Olszewska, D.A. Lim, S.-Y. Ahmad-Annuar, A. Tan, A.H. Al-Mubarak, B. Hanagasi, H. Koziorowski, D. Ertan, S. Genç, G. de Carvalho Aguiar, P. Barkhuizen, M. Pimentel, M.M.G. Saunders-Pullman, R. van de Warrenburg, B. Bressman, S. Toft, M. Appel-Cresswell, S. Lang, A.E. Skorvanek, M. Boon, A.J.W. Krüger, R. Sammler, E.M. Tumas, V. Zhang, B.-R. Garraux, G. Chung, S.J. Kim, Y.J. Winkelmann, J. Sue, C.M. Tan, E.-K. Damásio, J. Klivényi, P. Kostic, V.S. Arkadir, D. Martikainen, M. Borges, V. Hertz, J.M. Brighina, L. Spitz, M. Suchowersky, O. Riess, O. Das, P. Mollenhauer, B. Gatto, E.M. Petersen, M.S. Hattori, N. Wu, R.-M. Illarioshkin, S.N. Valente, E.M. Aasly, J.O. Aasly, A. Alcalay, R.N. Thaler, A. Farrer, M.J. Brockmann, K. Corvol, J.-C. Klein, C. Aasly, A. Aasly, J.O. Abramycheva, N.Y. Ahmad-Annuar, A. Albanese, A. Alcalay, R.N. Aldakheel, A. Alkhairallah, T. Al-Mubarak, B. Al-tassan, N. Alvarez, V. Amami, P. Annesi, G. Appel-Cresswell, S. Leite, M.A.A. Arkadir, D. Avenali, M. Ferraz, H.B. and Vollstedt, E.-J. Schaake, S. Lohmann, K. Padmanabhan, S. Brice, A. Lesage, S. Tesson, C. Vidailhet, M. Wurster, I. Hentati, F. Mirelman, A. Giladi, N. Marder, K. Waters, C. Fahn, S. Kasten, M. Brüggemann, N. Borsche, M. Foroud, T. Tolosa, E. Garrido, A. Annesi, G. Gagliardi, M. Bozi, M. Stefanis, L. Ferreira, J.J. Correia Guedes, L. Avenali, M. Petrucci, S. Clark, L. Fedotova, E.Y. Abramycheva, N.Y. Alvarez, V. Menéndez-González, M. Jesús Maestre, S. Gómez-Garre, P. Mir, P. Belin, A.C. Ran, C. Lin, C.-H. Kuo, M.-C. Crosiers, D. Wszolek, Z.K. Ross, O.A. Jankovic, J. Nishioka, K. Funayama, M. Clarimon, J. Williams-Gray, C.H. Camacho, M. Cornejo-Olivas, M. Torres-Ramirez, L. Wu, Y.-R. Lee-Chen, G.-J. Morgadinho, A. Pulkes, T. Termsarasab, P. Berg, D. Kuhlenbäumer, G. Kühn, A.A. Borngräber, F. de Michele, G. De Rosa, A. Zimprich, A. Puschmann, A. Mellick, G.D. Dorszewska, J. Carr, J. Ferese, R. Gambardella, S. Chase, B. Markopoulou, K. Satake, W. Toda, T. Rossi, M. Merello, M. Lynch, T. Olszewska, D.A. Lim, S.-Y. Ahmad-Annuar, A. Tan, A.H. Al-Mubarak, B. Hanagasi, H. Koziorowski, D. Ertan, S. Genç, G. de Carvalho Aguiar, P. Barkhuizen, M. Pimentel, M.M.G. Saunders-Pullman, R. van de Warrenburg, B. Bressman, S. Toft, M. Appel-Cresswell, S. Lang, A.E. Skorvanek, M. Boon, A.J.W. Krüger, R. Sammler, E.M. Tumas, V. Zhang, B.-R. Garraux, G. Chung, S.J. Kim, Y.J. Winkelmann, J. Sue, C.M. Tan, E.-K. Damásio, J. Klivényi, P. Kostic, V.S. Arkadir, D. Martikainen, M. Borges, V. Hertz, J.M. Brighina, L. Spitz, M. Suchowersky, O. Riess, O. Das, P. Mollenhauer, B. Gatto, E.M. Petersen, M.S. Hattori, N. Wu, R.-M. Illarioshkin, S.N. Valente, E.M. Aasly, J.O. Aasly, A. Alcalay, R.N. Thaler, A. Farrer, M.J. Brockmann, K. Corvol, J.-C. Klein, C. Aasly, A. Aasly, J.O. Abramycheva, N.Y. Ahmad-Annuar, A. Albanese, A. Alcalay, R.N. Aldakheel, A. Alkhairallah, T. Al-Mubarak, B. Al-tassan, N. Alvarez, V. Amami, P. Annesi, G. Appel-Cresswell, S. Leite, M.A.A. Arkadir, D. Avenali, M. Ferraz, H.B.
Abstract: Background: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the estimated number of subjects with monogenic PD worldwide are currently represented in the literature and availability of clinical data and clinical trial-ready cohorts is limited. Objective: The objectives are to (1) establish an international cohort of affected and unaffected individuals with PD-linked variants; (2) provide harmonized and quality-controlled clinical characterization data for each included individual; and (3) further promote collaboration of researchers in the field of monogenic PD. Methods: We conducted a worldwide, systematic online survey to collect individual-level data on individuals with PD-linked variants in SNCA, LRRK2, VPS35, PRKN, PINK1, DJ-1, as well as selected pathogenic and risk variants in GBA and corresponding demographic, clinical, and genetic data. All registered cases underwent thorough quality checks, and pathogenicity scoring of the variants and genotype–phenotype relationships were analyzed. Results: We collected 3888 variant carriers for our analyses, reported by 92 centers (42 countries) worldwide. Of the included individuals, 3185 had a diagnosis of PD (ie, 1306 LRRK2, 115 SNCA, 23 VPS35, 429 PRKN, 75 PINK1, 13 DJ-1, and 1224 GBA) and 703 were unaffected (ie, 328 LRRK2, 32 SNCA, 3 VPS35, 1 PRKN, 1 PINK1, and 338 GBA). In total, we identified 269 different pathogenic variants; 1322 individuals in our cohort (34%) were indicated as not previously published. Conclusions: Within the MJFF Global Genetic PD Study Group, we (1) established the largest international cohort of affected and unaffected individuals carrying PD-linked variants; (2) provide harmonized and quality-controlled clinical and genetic data for each included individual; (3) promote collaboration in the field of genetic PD with a view to
Published: 2023

5. Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort

Author: Vollstedt, E.J., Schaake, S., Lohmann, K., Padmanabhan, S., Brice, A., Lesage, S., Tesson, C., Vidailhet, M., Wurster, I., Hentati, F., Mirelman, A., Giladi, N., Marder, K., Waters, C., Fahn, S., Kasten, M., Brüggemann, N., Borsche, M., Foroud, T., Tolosa, E., Garrido, A., Annesi, G., Gagliardi, M., Bozi, M., Stefanis, L., Ferreira, J.J., Guedes, L. Correia, Avenali, M., Petrucci, S., Clark, L., Fedotova, E.Y., Abramycheva, N.Y., Alvarez, V., Menéndez-González, M., Maestre, S. Jesús, Gómez-Garre, P., Mir, P., Belin, A.C., Ran, C., Lin, Chih-Yu, Kuo, M.C., Crosiers, D., Wszolek, Z.K., Ross, O.A., Jankovic, J., Nishioka, K., Funayama, M., Clarimon, J., Williams-Gray, C.H., Camacho, M., Cornejo-Olivas, M., Torres-Ramirez, L., Wu, Y.R., Lee-Chen, G.J., Morgadinho, A., Pulkes, T., Termsarasab, P., Berg, D., Kuhlenbäumer, G., Kühn, A.A., Borngräber, F., Michele, G. de, Rosa, A. De, Zimprich, A., Puschmann, A., Mellick, G.D., Dorszewska, J., Carr, J., Ferese, R., Gambardella, S., Chase, B., Markopoulou, K., Satake, W., Toda, T., Rossi, M., Merello, M., Lynch, T., Olszewska, D.A., Lim, S.Y., Ahmad-Annuar, A., Tan, A.H., Al-Mubarak, B., Hanagasi, H., Koziorowski, D., Ertan, S., Genç, G., Aguiar, P. de Carvalho, Barkhuizen, M., Pimentel, M.M.G., Saunders-Pullman, R., Warrenburg, B.P.C. van de, Bressman, S., Toft, M., Appel-Cresswell, S., Lang, A.E., Skorvanek, M., Boon, A.J., Krüger, R., Sammler, E.M., Tumas, V., et al., Vollstedt, E.J., Schaake, S., Lohmann, K., Padmanabhan, S., Brice, A., Lesage, S., Tesson, C., Vidailhet, M., Wurster, I., Hentati, F., Mirelman, A., Giladi, N., Marder, K., Waters, C., Fahn, S., Kasten, M., Brüggemann, N., Borsche, M., Foroud, T., Tolosa, E., Garrido, A., Annesi, G., Gagliardi, M., Bozi, M., Stefanis, L., Ferreira, J.J., Guedes, L. Correia, Avenali, M., Petrucci, S., Clark, L., Fedotova, E.Y., Abramycheva, N.Y., Alvarez, V., Menéndez-González, M., Maestre, S. Jesús, Gómez-Garre, P., Mir, P., Belin, A.C., Ran, C., Lin, Chih-Yu, Kuo, M.C., Crosiers, D., Wszolek, Z.K., Ross, O.A., Jankovic, J., Nishioka, K., Funayama, M., Clarimon, J., Williams-Gray, C.H., Camacho, M., Cornejo-Olivas, M., Torres-Ramirez, L., Wu, Y.R., Lee-Chen, G.J., Morgadinho, A., Pulkes, T., Termsarasab, P., Berg, D., Kuhlenbäumer, G., Kühn, A.A., Borngräber, F., Michele, G. de, Rosa, A. De, Zimprich, A., Puschmann, A., Mellick, G.D., Dorszewska, J., Carr, J., Ferese, R., Gambardella, S., Chase, B., Markopoulou, K., Satake, W., Toda, T., Rossi, M., Merello, M., Lynch, T., Olszewska, D.A., Lim, S.Y., Ahmad-Annuar, A., Tan, A.H., Al-Mubarak, B., Hanagasi, H., Koziorowski, D., Ertan, S., Genç, G., Aguiar, P. de Carvalho, Barkhuizen, M., Pimentel, M.M.G., Saunders-Pullman, R., Warrenburg, B.P.C. van de, Bressman, S., Toft, M., Appel-Cresswell, S., Lang, A.E., Skorvanek, M., Boon, A.J., Krüger, R., Sammler, E.M., and Tumas, V., et al.
Abstract: Item does not contain fulltext, BACKGROUND: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the estimated number of subjects with monogenic PD worldwide are currently represented in the literature and availability of clinical data and clinical trial-ready cohorts is limited. OBJECTIVE: The objectives are to (1) establish an international cohort of affected and unaffected individuals with PD-linked variants; (2) provide harmonized and quality-controlled clinical characterization data for each included individual; and (3) further promote collaboration of researchers in the field of monogenic PD. METHODS: We conducted a worldwide, systematic online survey to collect individual-level data on individuals with PD-linked variants in SNCA, LRRK2, VPS35, PRKN, PINK1, DJ-1, as well as selected pathogenic and risk variants in GBA and corresponding demographic, clinical, and genetic data. All registered cases underwent thorough quality checks, and pathogenicity scoring of the variants and genotype-phenotype relationships were analyzed. RESULTS: We collected 3888 variant carriers for our analyses, reported by 92 centers (42 countries) worldwide. Of the included individuals, 3185 had a diagnosis of PD (ie, 1306 LRRK2, 115 SNCA, 23 VPS35, 429 PRKN, 75 PINK1, 13 DJ-1, and 1224 GBA) and 703 were unaffected (ie, 328 LRRK2, 32 SNCA, 3 VPS35, 1 PRKN, 1 PINK1, and 338 GBA). In total, we identified 269 different pathogenic variants; 1322 individuals in our cohort (34%) were indicated as not previously published. CONCLUSIONS: Within the MJFF Global Genetic PD Study Group, we (1) established the largest international cohort of affected and unaffected individuals carrying PD-linked variants; (2) provide harmonized and quality-controlled clinical and genetic data for each included individual; (3) promote collaboration in the field of genetic PD with a view toward
Published: 2023

6. Embracing monogenic Parkinson's disease: the MJFF Global Genetic PD cohort

Author: Ertan, Fatoş Sibel (ORCID 0000-0003-1339-243X & YÖK ID 112829), Vollstedt, E.J.; Schaake, S.; Lohmann, K.; Padmanabhan, S.; Brice, A.; Lesage, S.; Tesson, C.; Vidailhet, M.; Wurster, I.; Hentati, F.; Mirelman, A.; Giladi, N.; Marder, K.; Waters, C.; Fahn, S.; Kasten, M.; Brüggemann, N.; Borsche, M.; Foroud, T.; Tolosa, E.; Garrido, A.; Annesi, G.; Gagliardi, M.; Bozi, M.; Stefanis, L.; Ferreira, J.J.; Guedes, L.C.; Avenali, M.; Petrucci, S.; Clark, L.; Fedotova, E.Y.; Abramycheva, N.Y.; Alvarez, V.; Menéndez-González, M.; Maestre, SJ.; Gómez-Garre, P.; Mir, P.; Belin, A.C.; Ran, C.; Lin, C.H.; Kuo, M.C.; Crosiers, D.; Wszolek, Z.K.; Ross, O.A.; Jankovic, J.; Nishioka, K.; Funayama, M.; Clarimon, J.; Williams-Gray, C.H.; Camacho, M.; Cornejo-Olivas, M.; Torres-Ramirez, L.; Wu, YR.; Lee-Chen, G.J.; Morgadinho, A.; Pulkes, T.; Termsarasab, P.; Berg, D.; Kuhlenbäumer, G.; Kühn, A.A.; Borngräber, F.; de Michele, G.; De Rosa, A.; Zimprich, A.; Puschmann, A.; Mellick, GD.; Dorszewska, J.; Carr, J.; Ferese, R.; Gambardella, S.; Chase, B.; Markopoulou, K.; Satake, W.; Toda, T.; Rossi, M.; Merello, M.; Lynch, T.; Olszewska, D.A.; Lim, S.Y.; Ahmad-Annuar, A.; Tan, A.H.; Al-Mubarak, B.; Hanagasi, H.; Koziorowski, D.; Genç, G.; Aguiar, P.D.; Barkhuizen, M.; Pimentel, M.M.G.; Saunders-Pullman, R.; van de Warrenburg, B.; Bressman, S.; Toft, M.; Appel-Cresswell, S.; Lang, A.E.; Skorvanek, M.; Boon, A.J.W.; Krüger, R.; Sammler, E.M.; Tumas, V.; Zhang, B.R.; Garraux, G.; Chung, SJ.; Kim, Y.J.; Winkelmann, J.; Sue, C.M.; Tan, E.K.; Damásio, J.; Klivényi, P.; Kostic, V.S.; Arkadir, D.; Martikainen, M.; Borges, V.; Hertz, J.M.; Brighina, L.; Spitz, M.; Suchowersky, O.; Riess, O.; Das, P.; Mollenhauer, B.; Gatto, E.M.; Petersen, M.S.; Hattori, N.; Wu, R.M.; Illarioshkin, S.N.; Valente, E.M.; Aasly, J.O.; Aasly, A.; Alcalay, R.N.; Thaler, A.; Farrer, M.J.; Brockmann, K.; Corvol, J.C.; Klein, C., School of Medicine, Ertan, Fatoş Sibel (ORCID 0000-0003-1339-243X & YÖK ID 112829), Vollstedt, E.J.; Schaake, S.; Lohmann, K.; Padmanabhan, S.; Brice, A.; Lesage, S.; Tesson, C.; Vidailhet, M.; Wurster, I.; Hentati, F.; Mirelman, A.; Giladi, N.; Marder, K.; Waters, C.; Fahn, S.; Kasten, M.; Brüggemann, N.; Borsche, M.; Foroud, T.; Tolosa, E.; Garrido, A.; Annesi, G.; Gagliardi, M.; Bozi, M.; Stefanis, L.; Ferreira, J.J.; Guedes, L.C.; Avenali, M.; Petrucci, S.; Clark, L.; Fedotova, E.Y.; Abramycheva, N.Y.; Alvarez, V.; Menéndez-González, M.; Maestre, SJ.; Gómez-Garre, P.; Mir, P.; Belin, A.C.; Ran, C.; Lin, C.H.; Kuo, M.C.; Crosiers, D.; Wszolek, Z.K.; Ross, O.A.; Jankovic, J.; Nishioka, K.; Funayama, M.; Clarimon, J.; Williams-Gray, C.H.; Camacho, M.; Cornejo-Olivas, M.; Torres-Ramirez, L.; Wu, YR.; Lee-Chen, G.J.; Morgadinho, A.; Pulkes, T.; Termsarasab, P.; Berg, D.; Kuhlenbäumer, G.; Kühn, A.A.; Borngräber, F.; de Michele, G.; De Rosa, A.; Zimprich, A.; Puschmann, A.; Mellick, GD.; Dorszewska, J.; Carr, J.; Ferese, R.; Gambardella, S.; Chase, B.; Markopoulou, K.; Satake, W.; Toda, T.; Rossi, M.; Merello, M.; Lynch, T.; Olszewska, D.A.; Lim, S.Y.; Ahmad-Annuar, A.; Tan, A.H.; Al-Mubarak, B.; Hanagasi, H.; Koziorowski, D.; Genç, G.; Aguiar, P.D.; Barkhuizen, M.; Pimentel, M.M.G.; Saunders-Pullman, R.; van de Warrenburg, B.; Bressman, S.; Toft, M.; Appel-Cresswell, S.; Lang, A.E.; Skorvanek, M.; Boon, A.J.W.; Krüger, R.; Sammler, E.M.; Tumas, V.; Zhang, B.R.; Garraux, G.; Chung, SJ.; Kim, Y.J.; Winkelmann, J.; Sue, C.M.; Tan, E.K.; Damásio, J.; Klivényi, P.; Kostic, V.S.; Arkadir, D.; Martikainen, M.; Borges, V.; Hertz, J.M.; Brighina, L.; Spitz, M.; Suchowersky, O.; Riess, O.; Das, P.; Mollenhauer, B.; Gatto, E.M.; Petersen, M.S.; Hattori, N.; Wu, R.M.; Illarioshkin, S.N.; Valente, E.M.; Aasly, J.O.; Aasly, A.; Alcalay, R.N.; Thaler, A.; Farrer, M.J.; Brockmann, K.; Corvol, J.C.; Klein, C., and School of Medicine
Abstract: Background: as gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the estimated number of subjects with monogenic PD worldwide are currently represented in the literature and availability of clinical data and clinical trial-ready cohorts is limited. Objective: the objectives are to (1) establish an international cohort of affected and unaffected individuals with PD-linked variants; (2) provide harmonized and quality-controlled clinical characterization data for each included individual; and (3) further promote collaboration of researchers in the field of monogenic PD. Methods: we conducted a worldwide, systematic online survey to collect individual-level data on individuals with PD-linked variants in SNCA, LRRK2, VPS35, PRKN, PINK1, DJ-1, as well as selected pathogenic and risk variants in GBA and corresponding demographic, clinical, and genetic data. All registered cases underwent thorough quality checks, and pathogenicity scoring of the variants and genotype–phenotype relationships were analyzed. Results: we collected 3888 variant carriers for our analyses, reported by 92 centers (42 countries) worldwide. Of the included individuals, 3185 had a diagnosis of PD (ie, 1306 LRRK2, 115 SNCA, 23 VPS35, 429 PRKN, 75 PINK1, 13 DJ-1, and 1224 GBA) and 703 were unaffected (ie, 328 LRRK2, 32 SNCA, 3 VPS35, 1 PRKN, 1 PINK1, and 338 GBA). In total, we identified 269 different pathogenic variants; 1322 individuals in our cohort (34%) were indicated as not previously published. Conclusions: within the MJFF Global Genetic PD Study Group, we (1) established the largest international cohort of affected and unaffected individuals carrying PD-linked variants; (2) provide harmonized and quality-controlled clinical and genetic data for each included individual; (3) promote collaboration in the field of genetic PD with a view toward, Open Access funding enabled and organized by Projekt DEAL. Funding text 1: Carolyn M. Sue: Intellectual Property Rights: WO 2015/157794 A1. Advisory Boards: AbbVie. Employment: Northern Sydney Local Health District, Sydney, Australia. Honoraria: The International Movement Disorder Society for course directorships and invited lectures. Patents: WO 2015/157794 A1. Grants: 2018–22 NHMRC Partnership grant (APP1151906); 2018–22 MRFF NHMRC Practitioner Fellowship (App1136800); 2020–2025 NHMRC Partnership grant (APP11179029); 2020–2023 NHMRC Ideas Grant (APP1184403); 2021–5 MRFF 2020 Genomics Health Futures Mission Grant (APP2007959); 2021–23 ASAP Project grant ; Funding text 2: Natalya Y. Abramycheva: Employment: Research Center of Neurology, Ministry of Science and Higher Education of the Russian Federation, Moscow, Russia. Grants: Russian Science Foundation ; Funding text 3: Rachel Saunders?Pullman: Employment: Icahn School of Medicine at Mount Sinai, New York City, New York, USA. Grants: NIH 1U01NS107016?01A1; Bigglesworth Family Foundation. Others: Bachmann?Strauss Chair ; Funding text 4: Zbigniew K. Wszolek: Advisory Boards: Vigil Neuroscience, Inc. Employment: Mayo Clinic, Jacksonville, Florida, USA. Grants: NIH/NIA and NIH/NINDS (1U19AG063911, FAIN: U19AG063911), Mayo Clinic Center for Regenerative Medicine, PI or co?PI on Biohaven Pharmaceuticals, Inc. (BHV4157?206 and BHV3241?301), Neuraly, Inc. (NLY01?PD?1), and Vigil Neuroscience, Inc. (VGL101?01.001 and VGL101?01.002). He also serves as the co?PI of the Mayo Clinic APDA Center for Advanced Research. Others: Donations from the Donald G. and Jodi P. Heeringa Family, the Haworth Family Professorship in Neurodegenerative Diseases fund, and The Albertson Parkinson's Research Foundation ; Funding text 5: Vladimir S. Kostic: Employment: School of Medicine, University of Belgrade, Serbia. Grants: Project No 175090 Ministry of Education, Science and Technological Development of Serbia. Project ??28 Serbian Academy of S
Published: 2023

7. Nongenetic causes of Parkinson’s disease

Author: Chade, A. R., Kasten, M., Tanner, C. M., Riederer, P., editor, Reichmann, H., editor, Youdim, M. B. H., editor, and Gerlach, M., editor
Published: 2006
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8. Non‐motor symptoms and quality of life in subjects with mild parkinsonian signs

Author: Prasuhn, J., Piskol, L., Vollstedt, E.‐J., Graf, J., Schmidt, A., Tadic, V., Tunc, S., Hampf, J., Warrlich, E., Bibergeil, C., Hagenah, J., Klein, C., Kasten, M., and Brüggemann, N.
Published: 2017
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9. A0373 - Urodynamics: Imposition or not as bad as it seems? Secondary analyses from a randomized controlled trial

Author: Gross, O., Kasten, M., Wettstein, M., Anderson, C.E., Birkhäuser, V., Borer, J., Koschorke, M., Liechti, M.D., Mccallin, S., Mehnert, U., Röthlisberger, R., Sadri, H., Stächele, L., Van Der Lely, S., Kessler, T.M., and Leitner, L.
Published: 2024
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10. eXtremely Fast Tracker trigger upgrade at CDF

Author: Abulencia, A., Azzurri, P., Cochran, E., Cox, C., Cox, D., Dittmann, J., Donati, S., Efron, J., Erbacher, R., Errede, D., Fedorko, I., Flanagan, G., Forrest, R., Gerberich, H., Gartner, J., Hewamanage, S., Holm, S., Hughes, R., Ivanov, A., Jones, T., Johnson, M., Junk, T., Kasten, M., Kilminster, B., Klein, R., Krumnack, N., Lannon, K., Levine, S., Lister, A., McKim, J., Mokos, R., Olivito, D., Parks, B., Pitts, K., Rogers, E., Sartori, L., Schmidt, E., Scott, L., Shaw, T., Slaunwhite, J., Soha, A., Veramendi, G., Wilson, P.J., Wilson, J.S., and Winer, B.
Published: 2009
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11. Longitudinal study of mild motor impairment as probable predictor for Parkinsonʼs disease: 1023

Author: Hampf, J., Graf, J., Wolff, S., Staemmler, B., Piskol, L., Tunc, S., Klein, C., and Kasten, M.
Published: 2014

12. Changes in cognitive function after one year in an elderly population-based cohort to study non-motor-symptoms of Parkinsonʼs disease: 999

Author: Vollstedt, E.-J., Hampf, J., Graf, J., Tunc, S., Tadic, V., Lorwin, A., Piskol, L., Wolf, S., Klein, C., and Kasten, M.
Published: 2014

13. Characterization of sleep disturbances in a population-based cohort to investigate Parkinsonʼs disease: 809

Author: Tunc, S., Vollstedt, E.-J., Graf, J., Tadic, V., Warrlich, E., Lorwin, A., Hampf, J., Hagenah, J., Klein, C., and Kasten, M.
Published: 2014

14. Validation of photographic food records in children: are pictures really worth a thousand words?

Author: Higgins, J A, LaSalle, A L, Zhaoxing, P, Kasten, M Y, Bing, K N, Ridzon, S E, and Witten, T L
Published: 2009
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15. Using global team science to identify genetic parkinson's disease worldwide

Author: Vollstedt, E, Kasten, M, Klein, C, Aasly, J, Adler, C, Ahmad-Annuar, A, Albanese, A, Alcalay, R, Al-Mubarak, B, Alvarez, V, Andree-Munoz, B, Annesi, G, Appel-Cresswell, S, Arkadir, D, Armasu, S, Barber, T, Bardien, S, Barkhuizen, M, Barrett, M, Basak, A, Beach, T, Benitez, B, Berg, D, Bhatia, K, Binkofski, F, Blauwendraat, C, Bonifati, V, Borges, V, Bozi, M, Brice, A, Brighina, L, Brockmann, K, Brucke, T, Bruggemann, N, Camacho, M, Cardoso, F, Belin, A, Carr, J, Chan, P, Chang-Castello, J, Chase, B, Chen-Plotkin, A, Ju Chung, S, Cilia, R, Clarimon, J, Clark, L, Cornejo-Olivas, M, Corvol, J, Cosentino, C, Cras, P, Crosiers, D, Damasio, J, Das, P, de Carvalho Aguiar, P, De Michele, G, De Rosa, A, Dieguez, E, Dorszewska, J, Erer, S, Ertan, S, Farrer, M, Fedotova, E, Ferese, R, Ferrarese, C, Ferraz, H, Fiala, O, Foroud, T, Friedman, A, Frigerio, R, Funayama, M, Gambardella, S, Garraux, G, Gatto, E, Genc, G, Giladi, N, Goldwurm, S, Gomez-Esteban, J, Gomez-Garre, P, Gorostidi, A, Grosset, D, Hanagasi, H, Hardy, J, Hassan, A, Hattori, N, Hauser, R, Hedera, P, Hentati, F, Hertz, J, Holton, J, Houlden, H, Hutz, M, Ikeuchi, T, Illarioshkin, S, Inca-Martinez, M, Infante, J, Jankovic, J, Jeon, B, Jesus, S, Jimenez-Del-Rio, M, Kaasinen, V, Kataoka, H, Kawakami, H, Kim, Y, Klivenyi, P, Koks, S, Konig, I, Kostic, V, Koziorowski, D, Kruger, R, Krygowska-Wajs, A, Kulisevsky, J, Lai, D, Lang, A, Ledoux, M, Lesage, S, Lim, S, Lin, C, Lohmann, K, Lopera, F, Lopez, G, Lu, C, Lynch, T, Machaczka, M, Madoev, H, Magalhaes, M, Majamaa, K, Maraganore, D, Marder, K, Markopoulou, K, Martikainen, M, Mata, I, Mazzetti, P, Mellick, G, Menendez-Gonzalez, M, Micheli, F, Mirelman, A, Mir, P, Morino, H, Morris, H, Munhoz, R, Naito, A, Olszewska, D, Ozelius, L, Padmanabhan, S, Paisan-Ruiz, C, Payami, H, Peluso, S, Petkovic, S, Petrucci, S, Pezzoli, G, Pimentel, M, Pirker, W, Pramstaller, P, Pulkes, T, Puschmann, A, Quattrone, A, Raggio, V, Ransmayr, G, Rieder, C, Riess, O, Rodriguez-Porcel, F, Rogaeva, E, Ross, O, Ruiz-Martinez, J, Sammler, E, San Luciano, M, Satake, W, Saunders-Pullman, R, Sazci, A, Scherzer, C, Schrag, A, Schumacher-Schuh, A, Sharma, M, Sidransky, E, Singleton, A, Petersen, M, Smolders, S, Spitz, M, Stefanis, L, Struhal, W, Sue, C, Swan, M, Swanberg, M, Taba, P, Taipa, R, Tan, M, Tan, A, Tan, E, Tang, B, Tayebi, N, Thaler, A, Thomas, A, Toda, T, Toft, M, Torres, L, Tumas, V, Valente, E, Van Broeckhoven, C, Vecsei, L, Velez-Pardo, C, Vidailhet, M, Warner, T, Williams-Gray, C, Winkelmann, J, Woitalla, D, Wood, N, Wszolek, Z, Wu, R, Wu, Y, Xie, T, Yoshino, H, Zhang, B, Zimprich, A, Vollstedt E. -J., Kasten M., Klein C., Aasly J., Adler C., Ahmad-Annuar A., Albanese A., Alcalay R. N., Al-Mubarak B., Alvarez V., Andree-Munoz B., Annesi G., Appel-Cresswell S., Arkadir D., Armasu S., Barber T. R., Bardien S., Barkhuizen M., Barrett M. J., Basak A. N., Beach T., Benitez B. A., Berg D., Bhatia K., Binkofski F., Blauwendraat C., Bonifati V., Borges V., Bozi M., Brice A., Brighina L., Brockmann K., Brucke T., Bruggemann N., Camacho M., Cardoso F., Belin A. C., Carr J., Chan P., Chang-Castello J., Chase B., Chen-Plotkin A., Ju Chung S., Cilia R., Clarimon J., Clark L., Cornejo-Olivas M., Corvol J. -C., Cosentino C., Cras P., Crosiers D., Damasio J., Das P., de Carvalho Aguiar P., De Michele G., De Rosa A., Dieguez E., Dorszewska J., Erer S., Ertan S., Farrer M., Fedotova E., Ferese R., Ferrarese C., Ferraz H., Fiala O., Foroud T., Friedman A., Frigerio R., Funayama M., Gambardella S., Garraux G., Gatto E. M., Genc G., Giladi N., Goldwurm S., Gomez-Esteban J. C., Gomez-Garre P., Gorostidi A., Grosset D., Hanagasi H., Hardy J., Hassan A., Hattori N., Hauser R. A., Hedera P., Hentati F., Hertz J. M., Holton J. L., Houlden H., Hutz M. H., Ikeuchi T., Illarioshkin S., Inca-Martinez M., Infante J., Jankovic J., Jeon B. S., Jesus S., Jimenez-Del-Rio M., Kaasinen V., Kataoka H., Kawakami H., Kim Y. J., Klivenyi P., Koks S., Konig I. R., Kostic V., Koziorowski D., Kruger R., Krygowska-Wajs A., Kulisevsky J., Lai D., Lang A., LeDoux M., Lesage S., Lim S. -Y., Lin C. -H., Lohmann K., Lopera F., Lopez G., Lu C. -S., Lynch T., Machaczka M., Madoev H., Magalhaes M., Majamaa K., Maraganore D., Marder K., Markopoulou K., Martikainen M. H., Mata I., Mazzetti P., Mellick G., Menendez-Gonzalez M., Micheli F., Mirelman A., Mir P., Morino H., Morris H., Munhoz R. P., Naito A., Olszewska D. A., Ozelius L. J., Padmanabhan S., Paisan-Ruiz C., Payami H., Peluso S., Petkovic S., Petrucci S., Pezzoli G., Pimentel M., Pirker W., Pramstaller P. P., Pulkes T., Puschmann A., Quattrone A., Raggio V., Ransmayr G., Rieder C., Riess O., Rodriguez-Porcel F., Rogaeva E., Ross O. A., Ruiz-Martinez J., Sammler E., San Luciano M., Satake W., Saunders-Pullman R., Sazci A., Scherzer C., Schrag A., Schumacher-Schuh A., Sharma M., Sidransky E., Singleton A. B., Petersen M. S., Smolders S., Spitz M., Stefanis L., Struhal W., Sue C. M., Swan M., Swanberg M., Taba P., Taipa R., Tan M., Tan A. H., Tan E. -K., Tang B., Tayebi N., Thaler A., Thomas A., Toda T., Toft M., Torres L., Tumas V., Valente E. M., Van Broeckhoven C., Vecsei L., Velez-Pardo C., Vidailhet M., Warner T. T., Williams-Gray C. H., Winkelmann J., Woitalla D., Wood N. W., Wszolek Z. K., Wu R. -M., Wu Y. -R., Xie T., Yoshino H., Zhang B., Zimprich A., Vollstedt, E, Kasten, M, Klein, C, Aasly, J, Adler, C, Ahmad-Annuar, A, Albanese, A, Alcalay, R, Al-Mubarak, B, Alvarez, V, Andree-Munoz, B, Annesi, G, Appel-Cresswell, S, Arkadir, D, Armasu, S, Barber, T, Bardien, S, Barkhuizen, M, Barrett, M, Basak, A, Beach, T, Benitez, B, Berg, D, Bhatia, K, Binkofski, F, Blauwendraat, C, Bonifati, V, Borges, V, Bozi, M, Brice, A, Brighina, L, Brockmann, K, Brucke, T, Bruggemann, N, Camacho, M, Cardoso, F, Belin, A, Carr, J, Chan, P, Chang-Castello, J, Chase, B, Chen-Plotkin, A, Ju Chung, S, Cilia, R, Clarimon, J, Clark, L, Cornejo-Olivas, M, Corvol, J, Cosentino, C, Cras, P, Crosiers, D, Damasio, J, Das, P, de Carvalho Aguiar, P, De Michele, G, De Rosa, A, Dieguez, E, Dorszewska, J, Erer, S, Ertan, S, Farrer, M, Fedotova, E, Ferese, R, Ferrarese, C, Ferraz, H, Fiala, O, Foroud, T, Friedman, A, Frigerio, R, Funayama, M, Gambardella, S, Garraux, G, Gatto, E, Genc, G, Giladi, N, Goldwurm, S, Gomez-Esteban, J, Gomez-Garre, P, Gorostidi, A, Grosset, D, Hanagasi, H, Hardy, J, Hassan, A, Hattori, N, Hauser, R, Hedera, P, Hentati, F, Hertz, J, Holton, J, Houlden, H, Hutz, M, Ikeuchi, T, Illarioshkin, S, Inca-Martinez, M, Infante, J, Jankovic, J, Jeon, B, Jesus, S, Jimenez-Del-Rio, M, Kaasinen, V, Kataoka, H, Kawakami, H, Kim, Y, Klivenyi, P, Koks, S, Konig, I, Kostic, V, Koziorowski, D, Kruger, R, Krygowska-Wajs, A, Kulisevsky, J, Lai, D, Lang, A, Ledoux, M, Lesage, S, Lim, S, Lin, C, Lohmann, K, Lopera, F, Lopez, G, Lu, C, Lynch, T, Machaczka, M, Madoev, H, Magalhaes, M, Majamaa, K, Maraganore, D, Marder, K, Markopoulou, K, Martikainen, M, Mata, I, Mazzetti, P, Mellick, G, Menendez-Gonzalez, M, Micheli, F, Mirelman, A, Mir, P, Morino, H, Morris, H, Munhoz, R, Naito, A, Olszewska, D, Ozelius, L, Padmanabhan, S, Paisan-Ruiz, C, Payami, H, Peluso, S, Petkovic, S, Petrucci, S, Pezzoli, G, Pimentel, M, Pirker, W, Pramstaller, P, Pulkes, T, Puschmann, A, Quattrone, A, Raggio, V, Ransmayr, G, Rieder, C, Riess, O, Rodriguez-Porcel, F, Rogaeva, E, Ross, O, Ruiz-Martinez, J, Sammler, E, San Luciano, M, Satake, W, Saunders-Pullman, R, Sazci, A, Scherzer, C, Schrag, A, Schumacher-Schuh, A, Sharma, M, Sidransky, E, Singleton, A, Petersen, M, Smolders, S, Spitz, M, Stefanis, L, Struhal, W, Sue, C, Swan, M, Swanberg, M, Taba, P, Taipa, R, Tan, M, Tan, A, Tan, E, Tang, B, Tayebi, N, Thaler, A, Thomas, A, Toda, T, Toft, M, Torres, L, Tumas, V, Valente, E, Van Broeckhoven, C, Vecsei, L, Velez-Pardo, C, Vidailhet, M, Warner, T, Williams-Gray, C, Winkelmann, J, Woitalla, D, Wood, N, Wszolek, Z, Wu, R, Wu, Y, Xie, T, Yoshino, H, Zhang, B, Zimprich, A, Vollstedt E. -J., Kasten M., Klein C., Aasly J., Adler C., Ahmad-Annuar A., Albanese A., Alcalay R. N., Al-Mubarak B., Alvarez V., Andree-Munoz B., Annesi G., Appel-Cresswell S., Arkadir D., Armasu S., Barber T. R., Bardien S., Barkhuizen M., Barrett M. J., Basak A. N., Beach T., Benitez B. A., Berg D., Bhatia K., Binkofski F., Blauwendraat C., Bonifati V., Borges V., Bozi M., Brice A., Brighina L., Brockmann K., Brucke T., Bruggemann N., Camacho M., Cardoso F., Belin A. C., Carr J., Chan P., Chang-Castello J., Chase B., Chen-Plotkin A., Ju Chung S., Cilia R., Clarimon J., Clark L., Cornejo-Olivas M., Corvol J. -C., Cosentino C., Cras P., Crosiers D., Damasio J., Das P., de Carvalho Aguiar P., De Michele G., De Rosa A., Dieguez E., Dorszewska J., Erer S., Ertan S., Farrer M., Fedotova E., Ferese R., Ferrarese C., Ferraz H., Fiala O., Foroud T., Friedman A., Frigerio R., Funayama M., Gambardella S., Garraux G., Gatto E. M., Genc G., Giladi N., Goldwurm S., Gomez-Esteban J. C., Gomez-Garre P., Gorostidi A., Grosset D., Hanagasi H., Hardy J., Hassan A., Hattori N., Hauser R. A., Hedera P., Hentati F., Hertz J. M., Holton J. L., Houlden H., Hutz M. H., Ikeuchi T., Illarioshkin S., Inca-Martinez M., Infante J., Jankovic J., Jeon B. S., Jesus S., Jimenez-Del-Rio M., Kaasinen V., Kataoka H., Kawakami H., Kim Y. J., Klivenyi P., Koks S., Konig I. R., Kostic V., Koziorowski D., Kruger R., Krygowska-Wajs A., Kulisevsky J., Lai D., Lang A., LeDoux M., Lesage S., Lim S. -Y., Lin C. -H., Lohmann K., Lopera F., Lopez G., Lu C. -S., Lynch T., Machaczka M., Madoev H., Magalhaes M., Majamaa K., Maraganore D., Marder K., Markopoulou K., Martikainen M. H., Mata I., Mazzetti P., Mellick G., Menendez-Gonzalez M., Micheli F., Mirelman A., Mir P., Morino H., Morris H., Munhoz R. P., Naito A., Olszewska D. A., Ozelius L. J., Padmanabhan S., Paisan-Ruiz C., Payami H., Peluso S., Petkovic S., Petrucci S., Pezzoli G., Pimentel M., Pirker W., Pramstaller P. P., Pulkes T., Puschmann A., Quattrone A., Raggio V., Ransmayr G., Rieder C., Riess O., Rodriguez-Porcel F., Rogaeva E., Ross O. A., Ruiz-Martinez J., Sammler E., San Luciano M., Satake W., Saunders-Pullman R., Sazci A., Scherzer C., Schrag A., Schumacher-Schuh A., Sharma M., Sidransky E., Singleton A. B., Petersen M. S., Smolders S., Spitz M., Stefanis L., Struhal W., Sue C. M., Swan M., Swanberg M., Taba P., Taipa R., Tan M., Tan A. H., Tan E. -K., Tang B., Tayebi N., Thaler A., Thomas A., Toda T., Toft M., Torres L., Tumas V., Valente E. M., Van Broeckhoven C., Vecsei L., Velez-Pardo C., Vidailhet M., Warner T. T., Williams-Gray C. H., Winkelmann J., Woitalla D., Wood N. W., Wszolek Z. K., Wu R. -M., Wu Y. -R., Xie T., Yoshino H., Zhang B., and Zimprich A.
Published: 2019

16. The ATLAS Fast TracKer system

Author: Aad, G., additional, Abbott, B., additional, Abbott, D.C., additional, Abed Abud, A., additional, Abeling, K., additional, Abhayasinghe, D.K., additional, Abidi, S.H., additional, AbouZeid, O.S., additional, Abraham, N.L., additional, Abramowicz, H., additional, Abreu, H., additional, Abulaiti, Y., additional, Acharya, B.S., additional, Achkar, B., additional, Adam, L., additional, Adam Bourdarios, C., additional, Adamczyk, L., additional, Adamek, L., additional, Adelman, J., additional, Adiguzel, A., additional, Adorni, S., additional, Adye, T., additional, Affolder, A.A., additional, Afik, Y., additional, Agapopoulou, C., additional, Agaras, M.N., additional, Aggarwal, A., additional, Agheorghiesei, C., additional, Aguilar-Saavedra, J.A., additional, Ahmad, A., additional, Ahmadov, F., additional, Ahmed, W.S., additional, Ai, X., additional, Aielli, G., additional, Akatsuka, S., additional, Akbiyik, M., additional, Åkesson, T.P.A., additional, Akilli, E., additional, Akimov, A.V., additional, Al Khoury, K., additional, Alberghi, G.L., additional, Albert, J., additional, Albicocco, P., additional, Alconada Verzini, M.J., additional, Alderweireldt, S., additional, Aleksa, M., additional, Aleksandrov, I.N., additional, Alexa, C., additional, Alexopoulos, T., additional, Alfonsi, A., additional, Alfonsi, F., additional, Alhroob, M., additional, Ali, B., additional, Ali, S., additional, Aliev, M., additional, Alimonti, G., additional, Alison, J., additional, Allaire, C., additional, Allbrooke, B.M.M., additional, Allport, P.P., additional, Aloisio, A., additional, Alonso, F., additional, Alpigiani, C., additional, Alunno Camelia, E., additional, Alvarez Estevez, M., additional, Alviggi, M.G., additional, Amaral Coutinho, Y., additional, Ambler, A., additional, Ambroz, L., additional, Amelung, C., additional, Amidei, D., additional, Amor Dos Santos, S.P., additional, Amoroso, S., additional, Amrouche, C.S., additional, Anastopoulos, C., additional, Andari, N., additional, Andeen, T., additional, Anders, J.K., additional, Anderson, J.T., additional, Andrean, S.Y., additional, Andreazza, A., additional, Andrei, V., additional, Anelli, C.R., additional, Angelidakis, S., additional, Angerami, A., additional, Anisenkov, A.V., additional, Annovi, A., additional, Antel, C., additional, Anthony, M.T., additional, Antipov, E., additional, Antonelli, M., additional, Antrim, D.J.A., additional, Anulli, F., additional, Aoki, M., additional, Aparisi Pozo, J.A., additional, Aparo, M.A., additional, Aperio Bella, L., additional, Aranzabal, N., additional, Araujo Ferraz, V., additional, Araujo Pereira, R., additional, Arcangeletti, C., additional, Arce, A.T.H., additional, Arguin, J-F., additional, Argyropoulos, S., additional, Arling, J.-H., additional, Armbruster, A.J., additional, Armstrong, A., additional, Arnaez, O., additional, Arnold, H., additional, Arrubarrena Tame, Z.P., additional, Artoni, G., additional, Asada, H., additional, Asai, K., additional, Asai, S., additional, Asawatavonvanich, T., additional, Asbah, N., additional, Asimakopoulou, E.M., additional, Asquith, L., additional, Assahsah, J., additional, Assamagan, K., additional, Astalos, R., additional, Atkin, R.J., additional, Atkinson, M., additional, Atlay, N.B., additional, Atmani, H., additional, Atmasiddha, P.A., additional, Augsten, K., additional, Austrup, V.A., additional, Avolio, G., additional, Ayoub, M.K., additional, Azuelos, G., additional, Babal, D., additional, Bachacou, H., additional, Bachas, K., additional, Backman, F., additional, Bagnaia, P., additional, Bahmani, M., additional, Bahrasemani, H., additional, Bailey, A.J., additional, Bailey, V.R., additional, Baines, J.T., additional, Bakalis, C., additional, Baker, O.K., additional, Bakker, P.J., additional, Bakos, E., additional, Bakshi Gupta, D., additional, Balaji, S., additional, Balasubramanian, R., additional, Baldin, E.M., additional, Balek, P., additional, Balli, F., additional, Balunas, W.K., additional, Balz, J., additional, Banas, E., additional, Bandieramonte, M., additional, Bandyopadhyay, A., additional, Barak, L., additional, Barbe, W.M., additional, Barberio, E.L., additional, Barberis, D., additional, Barbero, M., additional, Barbour, G., additional, Barillari, T., additional, Barisits, M-S., additional, Barkeloo, J., additional, Barklow, T., additional, Barnett, B.M., additional, Barnett, R.M., additional, Barnovska-Blenessy, Z., additional, Baroncelli, A., additional, Barone, G., additional, Barr, A.J., additional, Barranco Navarro, L., additional, Barreiro, F., additional, Barreiro Guimarães da Costa, J., additional, Barron, U., additional, Barsov, S., additional, Bartels, F., additional, Bartoldus, R., additional, Bartolini, G., additional, Barton, A.E., additional, Bartos, P., additional, Basalaev, A., additional, Basan, A., additional, Bassalat, A., additional, Basso, M.J., additional, Basson, C.R., additional, Bates, R.L., additional, Batlamous, S., additional, Batley, J.R., additional, Batool, B., additional, Battaglia, M., additional, Bauce, M., additional, Bauer, F., additional, Bauer, P., additional, Bawa, H.S., additional, Bayirli, A., additional, Beacham, J.B., additional, Beau, T., additional, Beauchemin, P.H., additional, Becherer, F., additional, Bechtle, P., additional, Beck, H.P., additional, Becker, K., additional, Becot, C., additional, Beddall, A., additional, Beddall, A.J., additional, Bednyakov, V.A., additional, Bee, C.P., additional, Beermann, T.A., additional, Begalli, M., additional, Begel, M., additional, Behera, A., additional, Behr, J.K., additional, Beisiegel, F., additional, Belfkir, M., additional, Bella, G., additional, Bellagamba, L., additional, Bellerive, A., additional, Bellos, P., additional, Beloborodov, K., additional, Belotskiy, K., additional, Belyaev, N.L., additional, Benchekroun, D., additional, Benekos, N., additional, Benhammou, Y., additional, Benjamin, D.P., additional, Benoit, M., additional, Bensinger, J.R., additional, Bentvelsen, S., additional, Beresford, L., additional, Beretta, M., additional, Berge, D., additional, Bergeaas Kuutmann, E., additional, Berger, N., additional, Bergmann, B., additional, Bergsten, L.J., additional, Beringer, J., additional, Berlendis, S., additional, Bernardi, G., additional, Bernius, C., additional, Bernlochner, F.U., additional, Berry, T., additional, Berta, P., additional, Berthold, A., additional, Bertram, I.A., additional, Bessidskaia Bylund, O., additional, Bethke, S., additional, Betti, A., additional, Bevan, A.J., additional, Bhatta, S., additional, Bhattacharya, D.S., additional, Bhattarai, P., additional, Bhopatkar, V.S., additional, Bi, R., additional, Bianchi, R.M., additional, Biebel, O., additional, Biedermann, D., additional, Bielski, R., additional, Bierwagen, K., additional, Biesuz, N.V., additional, Biglietti, M., additional, Billoud, T.R.V., additional, Bindi, M., additional, Bingul, A., additional, Bini, C., additional, Biondi, S., additional, Birch-sykes, C.J., additional, Birman, M., additional, Bisanz, T., additional, Biswal, J.P., additional, Biswas, D., additional, Bitadze, A., additional, Bittrich, C., additional, Bjørke, K., additional, Blair, R.E., additional, Blazek, T., additional, Bloch, I., additional, Blocker, C., additional, Blue, A., additional, Blumenschein, U., additional, Bobbink, G.J., additional, Bobrovnikov, V.S., additional, Bogavac, D., additional, Bogdan, M., additional, Bogdanchikov, A.G., additional, Bohm, C., additional, Boisvert, V., additional, Bokan, P., additional, Bold, T., additional, Bomben, M., additional, Bona, M., additional, Bonilla, J.S., additional, Boonekamp, M., additional, Booth, C.D., additional, Borbély, A.G., additional, Borecka-Bielska, H.M., additional, Borgna, L.S., additional, Borisov, A., additional, Borissov, G., additional, Bortoletto, D., additional, Boscherini, D., additional, Bosman, M., additional, Bossio Sola, J.D., additional, Bouaouda, K., additional, Boudreau, J., additional, Bouhova-Thacker, E.V., additional, Boumediene, D., additional, Bouquet, R., additional, Bourlis, G., additional, Boveia, A., additional, Boyd, J., additional, Boye, D., additional, Boyko, I.R., additional, Bozson, A.J., additional, Bracinik, J., additional, Brahimi, N., additional, Brandt, G., additional, Brandt, O., additional, Braren, F., additional, Brau, B., additional, Brau, J.E., additional, Breaden Madden, W.D., additional, Brendlinger, K., additional, Brener, R., additional, Brenner, L., additional, Brenner, R., additional, Bressler, S., additional, Brickwedde, B., additional, Briglin, D.L., additional, Britton, D., additional, Britzger, D., additional, Brock, I., additional, Brock, R., additional, Brooijmans, G., additional, Brooks, W.K., additional, Brost, E., additional, Bruckman de Renstrom, P.A., additional, Brüers, B., additional, Bruncko, D., additional, Bruni, A., additional, Bruni, G., additional, Bruschi, M., additional, Bruscino, N., additional, Bryant, P., additional, Bryngemark, L., additional, Buanes, T., additional, Buat, Q., additional, Buchholz, P., additional, Buckley, A.G., additional, Budagov, I.A., additional, Bugge, M.K., additional, Bulekov, O., additional, Bullard, B.A., additional, Burch, T.J., additional, Burdin, S., additional, Burgard, C.D., additional, Burger, A.M., additional, Burghgrave, B., additional, Burr, J.T.P., additional, Burton, C.D., additional, Burzynski, J.C., additional, Büscher, V., additional, Buschmann, E., additional, Bussey, P.J., additional, Butler, J.M., additional, Buttar, C.M., additional, Butterworth, J.M., additional, Buttinger, W., additional, Buxo Vazquez, C.J., additional, Buzykaev, A.R., additional, Cabras, G., additional, Cabrera Urbán, S., additional, Caforio, D., additional, Cai, H., additional, Cairo, V.M.M., additional, Cakir, O., additional, Calace, N., additional, Calafiura, P., additional, Calderini, G., additional, Calfayan, P., additional, Callea, G., additional, Caloba, L.P., additional, Caltabiano, A., additional, Calvente Lopez, S., additional, Calvet, D., additional, Calvet, S., additional, Calvet, T.P., additional, Calvetti, M., additional, Camacho Toro, R., additional, Camarda, S., additional, Camarero Munoz, D., additional, Camarri, P., additional, Camerlingo, M.T., additional, Cameron, D., additional, Camincher, C., additional, Campana, S., additional, Campanelli, M., additional, Camplani, A., additional, Canale, V., additional, Canesse, A., additional, Cano Bret, M., additional, Cantero, J., additional, Cao, Y., additional, Capua, M., additional, Cardarelli, R., additional, Cardillo, F., additional, Carducci, G., additional, Carli, T., additional, Carlino, G., additional, Carlson, B.T., additional, Carlson, E.M., additional, Carminati, L., additional, Carney, R.M.D., additional, Caron, S., additional, Carquin, E., additional, Carrá, S., additional, Carratta, G., additional, Carter, J.W.S., additional, Carter, T.M., additional, Casado, M.P., additional, Casha, A.F., additional, Castiglia, E.G., additional, Castillo, F.L., additional, Castillo Garcia, L., additional, Castillo Gimenez, V., additional, Castro, N.F., additional, Catinaccio, A., additional, Catmore, J.R., additional, Cattai, A., additional, Cavaliere, V., additional, Cavasinni, V., additional, Celebi, E., additional, Celli, F., additional, Cerny, K., additional, Cerqueira, A.S., additional, Cerri, A., additional, Cerrito, L., additional, Cerutti, F., additional, Cervelli, A., additional, Cetin, S.A., additional, Chadi, Z., additional, Chakraborty, D., additional, Chan, J., additional, Chan, W.S., additional, Chan, W.Y., additional, Chapman, J.D., additional, Chargeishvili, B., additional, Charlton, D.G., additional, Charman, T.P., additional, Chatterjee, M., additional, Chau, C.C., additional, Chekanov, S., additional, Chekulaev, S.V., additional, Chelkov, G.A., additional, Chen, B., additional, Chen, C., additional, Chen, C.H., additional, Chen, H., additional, Chen, J., additional, Chen, S., additional, Chen, S.J., additional, Chen, X., additional, Chen, Y., additional, Chen, Y-H., additional, Cheng, H.C., additional, Cheng, H.J., additional, Cheplakov, A., additional, Cheremushkina, E., additional, Cherkaoui El Moursli, R., additional, Cheu, E., additional, Cheung, K., additional, Chevalérias, T.J.A., additional, Chevalier, L., additional, Chiarella, V., additional, Chiarelli, G., additional, Chiodini, G., additional, Chisholm, A.S., additional, Chitan, A., additional, Chiu, I., additional, Chiu, Y.H., additional, Chizhov, M.V., additional, Choi, K., additional, Chomont, A.R., additional, Chou, Y., additional, Chow, Y.S., additional, Christopher, L.D., additional, Chu, M.C., additional, Chu, X., additional, Chudoba, J., additional, Chwastowski, J.J., additional, Cieri, D., additional, Ciesla, K.M., additional, Cindro, V., additional, Cioară, I.A., additional, Ciocio, A., additional, Cirotto, F., additional, Citraro, S., additional, Citron, Z.H., additional, Citterio, M., additional, Ciubotaru, D.A., additional, Ciungu, B.M., additional, Clark, A., additional, Clark, P.J., additional, Clawson, S.E., additional, Clement, C., additional, Clissa, L., additional, Coadou, Y., additional, Cobal, M., additional, Coccaro, A., additional, Cochran, J., additional, Coelho Lopes De Sa, R., additional, Cohen, H., additional, Coimbra, A.E.C., additional, Cole, B., additional, Colijn, A.P., additional, Collot, J., additional, Conde Muiño, P., additional, Connell, S.H., additional, Connelly, I.A., additional, Conventi, F., additional, Cooper-Sarkar, A.M., additional, Cormier, F., additional, Corpe, L.D., additional, Corradi, M., additional, Corrigan, E.E., additional, Corriveau, F., additional, Costa, M.J., additional, Costanza, F., additional, Costanzo, D., additional, Cowan, G., additional, Cowley, J.W., additional, Crane, J., additional, Cranmer, K., additional, Creager, R.A., additional, Crépé-Renaudin, S., additional, Crescioli, F., additional, Cristinziani, M., additional, Cristoforetti, M., additional, Croft, V., additional, Crone, G.J., additional, Crosetti, G., additional, Cueto, A., additional, Cuhadar Donszelmann, T., additional, Cui, H., additional, Cukierman, A.R., additional, Cunningham, W.R., additional, Czekierda, S., additional, Czodrowski, P., additional, Czurylo, M.M., additional, Da Cunha Sargedas De Sousa, M.J., additional, Da Fonseca Pinto, J.V., additional, Da Via, C., additional, Dabrowski, W., additional, Dachs, F., additional, Dado, T., additional, Dahbi, S., additional, Dai, T., additional, Dallapiccola, C., additional, Dam, M., additional, D'amen, G., additional, D'Amico, V., additional, Damp, J., additional, Dandoy, J.R., additional, Daneri, M.F., additional, Danninger, M., additional, Dao, V., additional, Darbo, G., additional, Dartsi, O., additional, Dattagupta, A., additional, D'Auria, S., additional, David, C., additional, Davidek, T., additional, Davis, D.R., additional, Dawson, I., additional, De, K., additional, De Asmundis, R., additional, De Beurs, M., additional, De Castro, S., additional, De Groot, N., additional, De Jesus Pardal Vicente, M., additional, de Jong, P., additional, De la Torre, H., additional, De Maria, A., additional, De Pedis, D., additional, De Salvo, A., additional, De Sanctis, U., additional, De Santis, M., additional, De Santo, A., additional, De Vivie De Regie, J.B., additional, Dedovich, D.V., additional, Deiana, A.M., additional, Del Peso, J., additional, Delabat Diaz, Y., additional, Delgove, D., additional, Deliot, F., additional, Delitzsch, C.M., additional, Della Pietra, M., additional, Della Volpe, D., additional, Dell'Acqua, A., additional, Dell'Asta, L., additional, Delmastro, M., additional, Delporte, C., additional, Delsart, P.A., additional, Demers, S., additional, Demichev, M., additional, Demontigny, G., additional, Denisov, S.P., additional, D'Eramo, L., additional, Derendarz, D., additional, Derkaoui, J.E., additional, Derue, F., additional, Dervan, P., additional, Desch, K., additional, Dette, K., additional, Deutsch, C., additional, Deviveiros, P.O., additional, Di Bello, F.A., additional, Di Ciaccio, A., additional, Di Ciaccio, L., additional, Di Donato, C., additional, Di Girolamo, A., additional, Di Gregorio, G., additional, Di Luca, A., additional, Di Micco, B., additional, Di Nardo, R., additional, Di Sipio, R., additional, Diaconu, C., additional, Dias, F.A., additional, Dias Do Vale, T., additional, Diaz, M.A., additional, Diaz Capriles, F.G., additional, Dickinson, J., additional, Didenko, M., additional, Diehl, E.B., additional, Dietrich, J., additional, Díez Cornell, S., additional, Diez Pardos, C., additional, Dimitrievska, A., additional, Ding, W., additional, Dingfelder, J., additional, Dittmeier, S.J., additional, Dittus, F., additional, Djama, F., additional, Djobava, T., additional, Djuvsland, J.I., additional, Do Vale, M.A.B., additional, Dobre, M., additional, Dodsworth, D., additional, Doglioni, C., additional, Dolejsi, J., additional, Dolezal, Z., additional, Donadelli, M., additional, Dong, B., additional, Donini, J., additional, D'onofrio, A., additional, D'Onofrio, M., additional, Dopke, J., additional, Doria, A., additional, Dova, M.T., additional, Doyle, A.T., additional, Drake, G., additional, Drechsler, E., additional, Dreyer, E., additional, Dreyer, T., additional, Drobac, A.S., additional, Du, D., additional, du Pree, T.A., additional, Duan, Y., additional, Dubinin, F., additional, Dubovsky, M., additional, Dubreuil, A., additional, Duchovni, E., additional, Duckeck, G., additional, Ducu, O.A., additional, Duda, D., additional, Dudarev, A., additional, Dudder, A.C., additional, D'uffizi, M., additional, Duflot, L., additional, Dührssen, M., additional, Dülsen, C., additional, Dumancic, M., additional, Dumitriu, A.E., additional, Dunford, M., additional, Dungs, S., additional, Duperrin, A., additional, Duran Yildiz, H., additional, Düren, M., additional, Durglishvili, A., additional, Dutta, B., additional, Duvnjak, D., additional, Dyckes, G.I., additional, Dyndal, M., additional, Dysch, S., additional, Dziedzic, B.S., additional, Eggleston, M.G., additional, Eifert, T., additional, Eigen, G., additional, Einsweiler, K., additional, Ekelof, T., additional, El Jarrari, H., additional, Ellajosyula, V., additional, Ellert, M., additional, Ellinghaus, F., additional, Elliot, A.A., additional, Ellis, N., additional, Elmsheuser, J., additional, Elsing, M., additional, Emeliyanov, D., additional, Emerman, A., additional, Enari, Y., additional, Erdmann, J., additional, Ereditato, A., additional, Erland, P.A., additional, Errenst, M., additional, Escalier, M., additional, Escobar, C., additional, Estrada Pastor, O., additional, Etzion, E., additional, Evans, G., additional, Evans, H., additional, Evans, M.O., additional, Ezhilov, A., additional, Fabbri, F., additional, Fabbri, L., additional, Fabiani, V., additional, Facini, G., additional, Fakhrutdinov, R.M., additional, Falciano, S., additional, Falke, P.J., additional, Falke, S., additional, Faltova, J., additional, Fang, Y., additional, Fanourakis, G., additional, Fanti, M., additional, Faraj, M., additional, Farbin, A., additional, Farilla, A., additional, Farina, E.M., additional, Farooque, T., additional, Farrington, S.M., additional, Farthouat, P., additional, Fassi, F., additional, Fassnacht, P., additional, Fassouliotis, D., additional, Faucci Giannelli, M., additional, Fawcett, W.J., additional, Fayard, L., additional, Fedin, O.L., additional, Fehr, A., additional, Feickert, M., additional, Feligioni, L., additional, Fell, A., additional, Feng, C., additional, Feng, M., additional, Fenton, M.J., additional, Fenyuk, A.B., additional, Ferguson, S.W., additional, Ferrando, J., additional, Ferrari, A., additional, Ferrari, P., additional, Ferrari, R., additional, Ferrer, A., additional, Ferrere, D., additional, Ferretti, C., additional, Fiedler, F., additional, Filipčič, A., additional, Filthaut, F., additional, Finelli, K.D., additional, Fiolhais, M.C.N., additional, Fiorini, L., additional, Fischer, F., additional, Fischer, J., additional, Fisher, W.C., additional, Fitschen, T., additional, Fleck, I., additional, Fleischmann, P., additional, Flick, T., additional, Flierl, B.M., additional, Flores, L., additional, Flores Castillo, L.R., additional, Follega, F.M., additional, Fomin, N., additional, Foo, J.H., additional, Forcolin, G.T., additional, Forland, B.C., additional, Formica, A., additional, Förster, F.A., additional, Forti, A.C., additional, Fortin, E., additional, Foti, M.G., additional, Fournier, D., additional, Fox, H., additional, Francavilla, P., additional, Francescato, S., additional, Franchini, M., additional, Franchino, S., additional, Francis, D., additional, Franco, L., additional, Franconi, L., additional, Franklin, M., additional, Frattari, G., additional, Freeman, P.M., additional, Freund, B., additional, Freund, W.S., additional, Freundlich, E.M., additional, Frizzell, D.C., additional, Froidevaux, D., additional, Frost, J.A., additional, Fujimoto, M., additional, Fullana Torregrosa, E., additional, Fusayasu, T., additional, Fuster, J., additional, Gabrielli, A., additional, Gadow, P., additional, Gagliardi, G., additional, Gagnon, L.G., additional, Gallardo, G.E., additional, Gallas, E.J., additional, Gallop, B.J., additional, Gamboa Goni, R., additional, Gan, K.K., additional, Ganguly, S., additional, Gao, J., additional, Gao, Y., additional, Gao, Y.S., additional, Garay Walls, F.M., additional, García, C., additional, García Navarro, J.E., additional, García Pascual, J.A., additional, Garcia-Sciveres, M., additional, Gardner, R.W., additional, Garelli, N., additional, Gargiulo, S., additional, Garner, C.A., additional, Garonne, V., additional, Gasiorowski, S.J., additional, Gaspar, P., additional, Gatta, 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Trischuk, W., additional, Trocmé, B., additional, Trofymov, A., additional, Troncon, C., additional, Trovato, F., additional, Truong, L., additional, Trzebinski, M., additional, Trzupek, A., additional, Tsai, F., additional, Tsiareshka, P.V., additional, Tsirigotis, A., additional, Tsiskaridze, V., additional, Tskhadadze, E.G., additional, Tsopoulou, M., additional, Tsukerman, I.I., additional, Tsulaia, V., additional, Tsuno, S., additional, Tsybychev, D., additional, Tu, Y., additional, Tudorache, A., additional, Tudorache, V., additional, Tuna, A.N., additional, Turchikhin, S., additional, Turgeman, D., additional, Turk Cakir, I., additional, Turner, R.J., additional, Turra, R., additional, Tuts, P.M., additional, Tzamarias, S., additional, Tzovara, E., additional, Uchida, K., additional, Uehara, Y., additional, Ukegawa, F., additional, Unal, G., additional, Unal, M., additional, Undrus, A., additional, Unel, G., additional, Ungaro, F.C., additional, Uno, K., additional, Urban, J., additional, Urquijo, P., additional, Usai, G., additional, Uysal, Z., additional, Vacek, V., additional, Vachon, B., additional, Vadla, K.O.H., additional, Vafeiadis, T., additional, Vaidya, A., additional, Valderanis, C., additional, Valdes Santurio, E., additional, Valente, M., additional, Valentinetti, S., additional, Valero, A., additional, Valéry, L., additional, Vallance, R.A., additional, Vallier, A., additional, Valls Ferrer, J.A., additional, Van Daalen, T.R., additional, Van Gemmeren, P., additional, Van Stroud, S., additional, Van Vulpen, I., additional, Vanadia, M., additional, Vandelli, W., additional, Vandenbroucke, M., additional, Vandewall, E.R., additional, Vannicola, D., additional, Vari, R., additional, Varnes, E.W., additional, Varni, C., additional, Varol, T., additional, Varouchas, D., additional, Varvell, K.E., additional, Vasile, M.E., additional, Vasquez, G.A., additional, Vazeille, F., additional, Vazquez Furelos, D., additional, Vazquez Schroeder, T., additional, Veatch, J., additional, Vecchio, V., additional, Veen, M.J., additional, Veloce, L.M., additional, Veloso, F., additional, Veneziano, S., additional, Ventura, A., additional, Verbytskyi, A., additional, Verducci, M., additional, Vergis, C., additional, Verkerke, W., additional, Vermeulen, A.T., additional, Vermeulen, J.C., additional, Vernieri, C., additional, Verschuuren, P.J., additional, Vetterli, M.C., additional, Viaux Maira, N., additional, Vickey, T., additional, Vickey Boeriu, O.E., additional, Viehhauser, G.H.A., additional, Vigani, L., additional, Villa, M., additional, Villaplana Perez, M., additional, Villhauer, E.M., additional, Vilucchi, E., additional, Vincter, M.G., additional, Virdee, G.S., additional, Vishwakarma, A., additional, Vittori, C., additional, Vivarelli, I., additional, Vogel, M., additional, Vokac, P., additional, Von Ahnen, J., additional, von Buddenbrock, S.E., additional, Von Toerne, E., additional, Vorobel, V., additional, Vorobev, K., additional, Vos, M., additional, Vossebeld, J.H., additional, Vozak, M., additional, Vranjes, N., additional, Vranjes Milosavljevic, M., additional, Vrba, V., additional, Vreeswijk, M., additional, Vu, N.K., additional, Vuillermet, R., additional, Vukotic, I., additional, Wada, S., additional, Wagner, C., additional, Wagner, P., additional, Wagner, W., additional, Wahdan, S., additional, Wahlberg, H., additional, Wakasa, R., additional, Walbrecht, V.M., additional, Walder, J., additional, Walker, R., additional, Walker, S.D., additional, Walkowiak, W., additional, Wallangen, V., additional, Wang, A.M., additional, Wang, A.Z., additional, Wang, C., additional, Wang, H., additional, Wang, J., additional, Wang, P., additional, Wang, R.-J., additional, Wang, R., additional, Wang, S.M., additional, Wang, S., additional, Wang, T., additional, Wang, W.T., additional, Wang, W.X., additional, Wang, Y., additional, Wang, Z., additional, Wanotayaroj, C., additional, Warburton, A., additional, Ward, C.P., additional, Ward, R.J., additional, Warrack, N., additional, Watson, A.T., additional, Watson, M.F., additional, Watts, G., additional, Waugh, B.M., additional, Webb, A.F., additional, Weber, C., additional, Weber, M.S., additional, Weber, S.A., additional, Weber, S.M., additional, Wei, Y., additional, Weidberg, A.R., additional, Weingarten, J., additional, Weirich, M., additional, Weiser, C., additional, Wells, P.S., additional, Wenaus, T., additional, Wendland, B., additional, Wengler, T., additional, Wenig, S., additional, Wermes, N., additional, Wessels, M., additional, Weston, T.D., additional, Whalen, K., additional, Wharton, A.M., additional, White, A.S., additional, White, A., additional, White, M.J., additional, Whiteson, D., additional, Whitmore, B.W., additional, Wiedenmann, W., additional, Wiel, C., additional, Wielers, M., additional, Wieseotte, N., additional, Wiglesworth, C., additional, Wiik-Fuchs, L.A.M., additional, Wilkens, H.G., additional, Wilkins, 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Y., additional, Xu, Z., additional, Yabsley, B., additional, Yacoob, S., additional, Yallup, D.P., additional, Yamaguchi, N., additional, Yamaguchi, Y., additional, Yamatani, M., additional, Yamauchi, H., additional, Yamazaki, T., additional, Yamazaki, Y., additional, Yan, J., additional, Yan, Z., additional, Yang, H.J., additional, Yang, H.T., additional, Yang, S., additional, Yang, T., additional, Yang, X., additional, Yang, Y., additional, Yang, Z., additional, Yao, W-M., additional, Yap, Y.C., additional, Ye, H., additional, Ye, J., additional, Ye, S., additional, Yeletskikh, I., additional, Yexley, M.R., additional, Yin, P., additional, Yorita, K., additional, Yoshihara, K., additional, Young, C.J.S., additional, Young, C., additional, Yuan, R., additional, Yue, X., additional, Zaazoua, M., additional, Zabinski, B., additional, Zacharis, G., additional, Zaffaroni, E., additional, Zahreddine, J., additional, Zaitsev, A.M., additional, Zakareishvili, T., additional, Zakharchuk, N., additional, Zambito, S., additional, Zanzi, D., additional, Zeißner, S.V., additional, Zeitnitz, C., additional, Zemaityte, G., additional, Zeng, J.C., additional, Zenin, O., additional, Ženiš, T., additional, Zenz, S., additional, Zerradi, S., additional, Zerwas, D., additional, Zgubič, M., additional, Zhang, B., additional, Zhang, D.F., additional, Zhang, G., additional, Zhang, J., additional, Zhang, K., additional, Zhang, L., additional, Zhang, M., additional, Zhang, R., additional, Zhang, S., additional, Zhang, X., additional, Zhang, Y., additional, Zhang, Z., additional, Zhao, P., additional, Zhao, Y., additional, Zhao, Z., additional, Zhemchugov, A., additional, Zheng, Z., additional, Zhong, D., additional, Zhou, B., additional, Zhou, C., additional, Zhou, H., additional, Zhou, M., additional, Zhou, N., additional, Zhou, Y., additional, Zhu, C.G., additional, Zhu, C., additional, Zhu, H.L., additional, Zhu, H., additional, Zhu, J., additional, Zhu, Y., additional, Zhuang, X., additional, Zhukov, K., additional, Zhulanov, V., additional, Zieminska, D., additional, Zimine, N.I., additional, Zimmermann, S., additional, Zinonos, Z., additional, Ziolkowski, M., additional, Živković, L., additional, Zoccoli, A., additional, Zoch, K., additional, Zorbas, T.G., additional, Zou, R., additional, and Zwalinski, L., additional
Published: 2021
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17. The CDF II level 1 track trigger upgrade

Author: Jones, M., Abulencia, A., Azzurri, P., Brian, W., Cochran, E., Dittmann, J.R., Donati, S., Efron, J., Erbacher, R., Errede, D., Fedorko, I., Flanagan, G., Forrest, R., Frank, M., Gartner, J., Gerberich, H., Hewamanage, S., Holm, S., Hughes, R., Ivanov, A., Johnson, M., Junk, T., Kasten, M., Kilminster, B., Klein, R., Krumnack, N., Lannon, K., Levine, S., Lister, A., McKim, J., Mokos, R., Olivito, D., Parks, B., Pitts, K., Rogers, E., Schmidt, E.E., Scott, L., Shaw, T., Slaunwhite, J., Soha, A., Staveris, A., Veramendi, G., Wilson, J.S., Wilson, P.J., and Winer, B.
Subjects: Colliders (Nuclear physics) -- Usage, Radiation warning systems -- Usage, Business, Electronics, Electronics and electrical industries
Abstract: The CDF II detector uses dedicated hardware to identify charged tracks that are used in an important class of level 1 trigger decisions. Until now, this hardware identified track segments based on patterns of hits on only the axial sense wires in the tracking chamber and determined the transverse momentum of track candidates from patterns of track segments. This identification is efficient but produces trigger rates that grow rapidly with increasing instantaneous luminosity. High trigger rates are a consequence of the large numbers of low momentum tracks produced in inelastic p[bar.p] collisions which generate overlapping patterns of hits that match those expected for high-momentum tracks. A recently completed upgrade to the level 1 track trigger system makes use of information from stereo wires in the tracking chamber to reduce the rate of false triggers while maintaining high efficiency for real high momentum particles. We describe the new electronics used to instrument the additional sense wires, identify track segments and correlate these with the track candidates found by the original track trigger system. The performance of this system is characterized in terms of the efficiency for identifying charged particles and the improved rejection of axial track candidates that do not correspond to real particles. Index Terms--Collider detector at fermilab (CDF), extremely fast tracker (XFT), on-line track processor, trigger.
Published: 2008

18. Substantia nigra hyperechogenicity correlates with clinical status and number of Parkin mutated alleles

Author: Hagenah, J. M., König, I. R., Becker, B., Hilker, R., Kasten, M., Hedrich, K., Pramstaller, P. P., Klein, C., and Seidel, G.
Published: 2007
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19. Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson’s disease

Author: Liu, G., Peng, J., Liao, Z., Locascio, J.J., Corvol, J-C, Zhu, F., Dong, X., Maple-Grødem, J., Campbell, M.C., Elbaz, A., Lesage, S., Brice, A., Mangone, G., Growdon, J.H., Hung, A.Y., Schwarzschild, M.A., Hayes, M.T., Wills, A-M, Herrington, T.M., Ravina, B., Shoulson, I., Taba, P., Kõks, S., Beach, T.G., Cormier-Dequaire, F., Alves, G., Tysnes, O-B, Perlmutter, J.S., Heutink, P., Amr, S.S., van Hilten, J.J., Kasten, M., Mollenhauer, B., Trenkwalder, C., Klein, C., Barker, R.A., Williams-Gray, C.H., Marinus, J., Scherzer, C.R., Liu, G., Peng, J., Liao, Z., Locascio, J.J., Corvol, J-C, Zhu, F., Dong, X., Maple-Grødem, J., Campbell, M.C., Elbaz, A., Lesage, S., Brice, A., Mangone, G., Growdon, J.H., Hung, A.Y., Schwarzschild, M.A., Hayes, M.T., Wills, A-M, Herrington, T.M., Ravina, B., Shoulson, I., Taba, P., Kõks, S., Beach, T.G., Cormier-Dequaire, F., Alves, G., Tysnes, O-B, Perlmutter, J.S., Heutink, P., Amr, S.S., van Hilten, J.J., Kasten, M., Mollenhauer, B., Trenkwalder, C., Klein, C., Barker, R.A., Williams-Gray, C.H., Marinus, J., and Scherzer, C.R.
Abstract: A key driver of patients’ well-being and clinical trials for Parkinson’s disease (PD) is the course that the disease takes over time (progression and prognosis). To assess how genetic variation influences the progression of PD over time to dementia, a major determinant for quality of life, we performed a longitudinal genome-wide survival study of 11.2 million variants in 3,821 patients with PD over 31,053 visits. We discover RIMS2 as a progression locus and confirm this in a replicate population (hazard ratio (HR) = 4.77, P = 2.78 × 10−11), identify suggestive evidence for TMEM108 (HR = 2.86, P = 2.09 × 10−8) and WWOX (HR = 2.12, P = 2.37 × 10−8) as progression loci, and confirm associations for GBA (HR = 1.93, P = 0.0002) and APOE (HR = 1.48, P = 0.001). Polygenic progression scores exhibit a substantial aggregate association with dementia risk, while polygenic susceptibility scores are not predictive. This study identifies a novel synaptic locus and polygenic score for cognitive disease progression in PD and proposes diverging genetic architectures of progression and susceptibility.
Published: 2021

20. Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease

Author: Ricke-Hoch, M, Stelling, E, Lasswitz, L, Gunesch, A, Kasten, M, Zapatero-Belinchón, F, Brogden, G, Gerold, G, Battmer, K, Pietschmann, T, Montiel, V, Balligand, J, Facciotti, F, Hirsch, E, Elbahesh, H, Rimmelzwaan, G, Hoefer, A, Kühnel, M, Jonigk, D, Eigendorf, J, Tegtbur, U, Mink, L, Scherr, M, Illig, T, Schambach, A, Pfeffer, T, Andrée, B, Hilfiker, A, Haverich, A, Hilfiker-Kleiner, D, Ricke-Hoch, Melanie, Stelling, Elisabeth, Lasswitz, Lisa, Gunesch, Antonia-Patricia, Kasten, Martina, Zapatero-Belinchón, Francisco J., Brogden, Graham, Gerold, Gisa, Battmer, Karin, Pietschmann, Thomas, Montiel, Virginie, Balligand, Jean-Luc, Facciotti, Federica, Hirsch, Emilio, Elbahesh, Husni, Rimmelzwaan, Guus, Hoefer, Anne, Kühnel, Mark, Jonigk, Danny, Eigendorf, Julian, Tegtbur, Uwe, Mink, Lena, Scherr, Michaela, Illig, Thomas, Schambach, Axel, Pfeffer, Tobias, Andrée, Birgit, Hilfiker, Andres, Haverich, Axel, Hilfiker-Kleiner, Denise, Ricke-Hoch, M, Stelling, E, Lasswitz, L, Gunesch, A, Kasten, M, Zapatero-Belinchón, F, Brogden, G, Gerold, G, Battmer, K, Pietschmann, T, Montiel, V, Balligand, J, Facciotti, F, Hirsch, E, Elbahesh, H, Rimmelzwaan, G, Hoefer, A, Kühnel, M, Jonigk, D, Eigendorf, J, Tegtbur, U, Mink, L, Scherr, M, Illig, T, Schambach, A, Pfeffer, T, Andrée, B, Hilfiker, A, Haverich, A, Hilfiker-Kleiner, D, Ricke-Hoch, Melanie, Stelling, Elisabeth, Lasswitz, Lisa, Gunesch, Antonia-Patricia, Kasten, Martina, Zapatero-Belinchón, Francisco J., Brogden, Graham, Gerold, Gisa, Battmer, Karin, Pietschmann, Thomas, Montiel, Virginie, Balligand, Jean-Luc, Facciotti, Federica, Hirsch, Emilio, Elbahesh, Husni, Rimmelzwaan, Guus, Hoefer, Anne, Kühnel, Mark, Jonigk, Danny, Eigendorf, Julian, Tegtbur, Uwe, Mink, Lena, Scherr, Michaela, Illig, Thomas, Schambach, Axel, Pfeffer, Tobias, Andrée, Birgit, Hilfiker, Andres, Haverich, Axel, and Hilfiker-Kleiner, Denise
Abstract: The SARS-CoV-2 coronavirus has led to a pandemic with millions of people affected. The present study finds that risk-factors for severe COVID-19 disease courses, i.e. male sex, older age and sedentary life style are associated with higher prostaglandin E2 (PGE2) serum levels in blood samples from unaffected subjects. In COVID-19 patients, PGE2 blood levels are markedly elevated and correlate positively with disease severity. SARS-CoV-2 induces PGE2 generation and secretion in infected lung epithelial cells by upregulating cyclo-oxygenase (COX)-2 and reducing the PG-degrading enzyme 15-hydroxyprostaglandin-dehydrogenase. Also living human precision cut lung slices (PCLS) infected with SARS-CoV-2 display upregulated COX-2. Regular exercise in aged individuals lowers PGE2 serum levels, which leads to increased Paired-Box-Protein-Pax-5 (PAX5) expression, a master regulator of B-cell survival, proliferation and differentiation also towards long lived memory B-cells, in human pre-B-cell lines. Moreover, PGE2 levels in serum of COVID-19 patients lowers the expression of PAX5 in human pre-B-cell lines. The PGE2 inhibitor Taxifolin reduces SARS-CoV-2-induced PGE2 production. In conclusion, SARS-CoV-2, male sex, old age, and sedentary life style increase PGE2 levels, which may reduce the early anti-viral defense as well as the development of immunity promoting severe disease courses and multiple infections. Regular exercise and Taxifolin treatment may reduce these risks and prevent severe disease courses.
Published: 2021

21. The CDF II eXtremely Fast Tracker Upgrade

Author: Abulencia, A., Errede, D., Gerberich, H., Junk, T., Kasten, M., Levine, S., Mokos, R., Pitts, K., Rogers, E., Veramendi, G., Azzurri, P., Donati, S., Dittmann, J.R., Hewamanage, S., Krumnack, N., Wilson, J.S., Erbacher, R., Forrest, R., Ivanov, A., Lister, A., Soha, A., Fedorko, I., Giokaris, N., Staveris-Polykalas, A., Cochran, E., Efron, J., Gartner, J., Hughes, R., Johnson, M., Kilmninster, B., Lannon, K., McKim, J., Olivito, D., Parks, B., Slaunwhite, J., Winer, B., Flanagan, G., Jones, T., Holm, S., Klein, R., Schmidt, E.E., Scott, L., Shaw, T., and Wilson, P.J.
Published: 2007
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22. Identification of the Saccharomyces cerevisiae genes STB1–STB5 encoding Sin3p binding proteins

Author: Kasten, M. M. and Stillman, D. J.
Published: 1997
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23. A fast hardware tracker for the ATLAS trigger system

Author: Anderson, J., Andreani, A., Andreazza, A., Annovi, A., Atkinson, M., Auerbach, B., Beretta, M., Bevacqua, V., Blair, R., Blazey, G., Bogdan, M., Boveia, A., Canelli, F., Castegnaro, A., Cavaliere, V., Cervigni, F., Chang, P., Cheng, Y., Citterio, M., Crescioli, F., Dell'Orso, M., Drake, G., Dunford, M., Fabbri, L., Favareto, A., Franchini, M., Geer, S., Giannetti, P., Giannuzzi, F., Giorgi, F., Gruenendahl, S., Li, H.L., Hoff, J., Iizawa, T., Kapliy, A., Kasten, M., Kim, Y.K., Kimura, N., Lanza, A., Lasagni, F., Liberali, V., Liu, T., Magalotti, D., McCarn, A., Melachrinos, C., Meroni, C., Mitani, T., Murat, P., Negri, A., Neubauer, M., Okumura, Y., Olsen, J., Penning, B., Piendibene, M., Proudfoot, J., Roda, C., Sacco, I., Sakurai, Y., Sbarra, C., Shochet, M., Stabile, A., Tang, J., Tang, F., Tompkins, L., Tripiccione, R., Tuggle, J., Valentinetti, S., Vercesi, V., Verzocchi, M., Villa, M., Volpi, G., Webster, J., Yorita, K., Zhang, J., and Zoccoli, A.
Published: 2013
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24. Motor reorganization in asymptomatic carriers of a single mutant Parkin allele: a human model for presymptomatic parkinsonism

Author: Buhmann, C., Binkofski, F., Klein, C., Büchel, C., van Eimeren, T., Erdmann, C., Hedrich, K., Kasten, M., Hagenah, J., Deuschl, G., Pramstaller, P. P., and Siebner, H. R.
Published: 2005

25. Campylobacter fetus subspecies fetus infection

Author: Allerberger, F., Kasten, M. J., and Anhalt, J. P.
Published: 1991
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26. Increased frequency of migraine in narcoleptic patients: a confirmatory study

Author: Dahmen, N, Kasten, M, Wieczorek, S, Gencik, M, Epplen, J T, and Ullrich, B
Published: 2003

27. Single-cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes

Author: Lang, C, Campbell, K, Ryan, B, Carling, P, Attar, M, Vowles, J, Perestenko, O, Bowden, R, Baig, F, Kasten, M, Hu, M, Cowley, S, Webber, C, and Wade-Martins, R
Abstract: Induced pluripotent stem cell (iPSC)-derived dopamine neurons provide an opportunity to model Parkinson’s disease (PD), but neuronal cultures are confounded by asynchronous and heterogeneous appearance of disease phenotypes in vitro. Using high-resolution, single-cell transcriptomic analyses of iPSC-derived dopamine neurons carrying the GBA-N370S PD risk variant, we identified a progressive axis of gene expression variation leading to endoplasmic reticulum stress. Pseudotime analysis of genes differentially expressed (DE) along this axis identified the transcriptional repressor histone deacetylase 4 (HDAC4) as an upstream regulator of disease progression. HDAC4 was mislocalized to the nucleus in PD iPSC-derived dopamine neurons and repressed genes early in the disease axis, leading to late deficits in protein homeostasis. Treatment of iPSC-derived dopamine neurons with HDAC4-modulating compounds upregulated genes early in the DE axis and corrected PD-related cellular phenotypes. Our study demonstrates how single-cell transcriptomics can exploit cellular heterogeneity to reveal disease mechanisms and identify therapeutic targets.
Published: 2018

28. Listeria monocytogenes infection in prosthetic joints

Author: Allerberger, F., Kasten, M. J., Cockerill, III, F. R., Krismer, M., and Dierich, M. P.
Published: 1992
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29. Using global team science to identify genetic Parkinson's disease worldwide

Author: Vollstedt, E‐J, Kasten, M., Klein, C., Aasly, J., Adler, C., Ahmad‐Annuar, A., Albanese, A., Alcalay, R., Al‐Mubarak, B., Alvarez, V., Andree‐Muñoz, B., Annesi, G., Appel‐Cresswell, S., Arkadir, D., Armasu, S., Barber, T.R., Bardien, S., Barkhuizen, M., Barrett, M.J., BaŞak, A.N., Beach, T., Benitez, B.A., Berg, D., Bhatia, K., Binkofski, F., Blauwendraat, C., Bonifati, V., Borges, V., Bozi, M., Brice, A., Brighina, L., Brockmann, K., Brüggemann, N., Camacho, M., Cardoso, F., Belin, A.C., Carr, J., Chan, P., Chang‐Castello, J., Chase, B., Chen‐Plotkin, A., Chung, S.J., Cilia, R., Clarimon, J., Clark, L., Cornejo‐Olivas, M., Corvol, J‐C, Cosentino, C., Cras, P., Crosiers, D., Damásio, J., Das, P., Carvalho Aguiar, P., De Michele, G., De Rosa, A., Dieguez, E., Dorszewska, J., Erer, S., Ertan, S., Farrer, M., Fedotova, E., Ferese, R., Ferrarese, C., Ferraz, H., Fiala, O., Foroud, T., Friedman, A., Frigerio, R., Funayama, M., Gambardella, S., Garraux, G., Gatto, E.M., Genç, G., Goldwurm, S., Gomez‐Esteban, J.C., Gómez‐Garre, P., Gorostidi, A., Grosset, D., Hanagasi, H., Hardy, J., Hassan, A., Hattori, N., Hauser, R.A., Hedera, P., Hentati, F., Hertz, J.M., Holton, J.L., Houlden, H., Hutz, M.H., Ikeuchi, T., Illarioshkin, S., Inca‐Martinez, M., Infante, J., Jankovic, J., Jeon, B.S., Jesús, S., Jimenez‐Del‐Rio, M., Kataoka, H., Kawakami, H., Kim, Y.J., Klivényi, P., Kõks, S., König, I.R., KostiĆ, V., Koziorowski, D., Krüger, R., Krygowska‐Wajs, A., Kulisevsky, J., Lang, A., LeDoux, M., Lesage, S., Lim, S‐Y, Lin, C‐H, Lohmann, K., Lopera, F., Lopez, G., Lu, C‐S, Lynch, T., Machaczka, M., Madoev, H., Magalhães, M., Majamaa, K., Maraganore, D., Marder, K., Markopoulou, K., Martikainen, M.H., Mata, I., Mazzetti, P., Mellick, G., Menéndez‐González, M., Micheli, F., Mirelman, A., Mir, P., Morino, H., Morris, H., Munhoz, R.P., Naito, A., Olszewska, D.A., Ozelius, L.J., Padmanabhan, S., Paisán‐Ruiz, C., Payami, H., Peluso, S., Petkovic, S., Petrucci, S., Pezzoli, G., Pimentel, M., Pirker, W., Pramstaller, P.P., Pulkes, T., Puschmann, A., Quattrone, A., Raggio, V., Ransmayr, G., Rieder, C., Riess, O., Rodriguez‐Porcel, F., Rogaeva, E., Ross, O.A., Ruiz‐Martinez, J., Sammler, E., Luciano, M.S., Satake, W., Saunders‐Pullman, R., Sazci, A., Scherzer, C., Schrag, A., Schumacher‐Schuh, A., Sharma, M., Sidransky, E., Singleton, A.B., Petersen, M.S., Smolders, S., Spitz, M., Stefanis, L., Struhal, W., Sue, C., Swan, M., Swanberg, M., Taba, P., Taipa, R., Tan, M., Tan, A.H., Tan, E‐K, Tang, B., Tayebi, N., Thaler, A., Thomas, A., Toda, T., Toft, M., Torres, L., Tumas, V., Valente, E.M., Van Broeckhoven, C., Vecsei, L., Velez‐Pardo, C., Vidailhet, M., Warner, T.T., Williams‐Gray, C.H., Winkelmann, J., Woitalla, D., Wood, N.W., Wszolek, Z.K., Wu, R‐M, Wu, Y‐R, Xie, T., Yoshino, H., Zhang, B., Zimprich, A., Vollstedt, E‐J, Kasten, M., Klein, C., Aasly, J., Adler, C., Ahmad‐Annuar, A., Albanese, A., Alcalay, R., Al‐Mubarak, B., Alvarez, V., Andree‐Muñoz, B., Annesi, G., Appel‐Cresswell, S., Arkadir, D., Armasu, S., Barber, T.R., Bardien, S., Barkhuizen, M., Barrett, M.J., BaŞak, A.N., Beach, T., Benitez, B.A., Berg, D., Bhatia, K., Binkofski, F., Blauwendraat, C., Bonifati, V., Borges, V., Bozi, M., Brice, A., Brighina, L., Brockmann, K., Brüggemann, N., Camacho, M., Cardoso, F., Belin, A.C., Carr, J., Chan, P., Chang‐Castello, J., Chase, B., Chen‐Plotkin, A., Chung, S.J., Cilia, R., Clarimon, J., Clark, L., Cornejo‐Olivas, M., Corvol, J‐C, Cosentino, C., Cras, P., Crosiers, D., Damásio, J., Das, P., Carvalho Aguiar, P., De Michele, G., De Rosa, A., Dieguez, E., Dorszewska, J., Erer, S., Ertan, S., Farrer, M., Fedotova, E., Ferese, R., Ferrarese, C., Ferraz, H., Fiala, O., Foroud, T., Friedman, A., Frigerio, R., Funayama, M., Gambardella, S., Garraux, G., Gatto, E.M., Genç, G., Goldwurm, S., Gomez‐Esteban, J.C., Gómez‐Garre, P., Gorostidi, A., Grosset, D., Hanagasi, H., Hardy, J., Hassan, A., Hattori, N., Hauser, R.A., Hedera, P., Hentati, F., Hertz, J.M., Holton, J.L., Houlden, H., Hutz, M.H., Ikeuchi, T., Illarioshkin, S., Inca‐Martinez, M., Infante, J., Jankovic, J., Jeon, B.S., Jesús, S., Jimenez‐Del‐Rio, M., Kataoka, H., Kawakami, H., Kim, Y.J., Klivényi, P., Kõks, S., König, I.R., KostiĆ, V., Koziorowski, D., Krüger, R., Krygowska‐Wajs, A., Kulisevsky, J., Lang, A., LeDoux, M., Lesage, S., Lim, S‐Y, Lin, C‐H, Lohmann, K., Lopera, F., Lopez, G., Lu, C‐S, Lynch, T., Machaczka, M., Madoev, H., Magalhães, M., Majamaa, K., Maraganore, D., Marder, K., Markopoulou, K., Martikainen, M.H., Mata, I., Mazzetti, P., Mellick, G., Menéndez‐González, M., Micheli, F., Mirelman, A., Mir, P., Morino, H., Morris, H., Munhoz, R.P., Naito, A., Olszewska, D.A., Ozelius, L.J., Padmanabhan, S., Paisán‐Ruiz, C., Payami, H., Peluso, S., Petkovic, S., Petrucci, S., Pezzoli, G., Pimentel, M., Pirker, W., Pramstaller, P.P., Pulkes, T., Puschmann, A., Quattrone, A., Raggio, V., Ransmayr, G., Rieder, C., Riess, O., Rodriguez‐Porcel, F., Rogaeva, E., Ross, O.A., Ruiz‐Martinez, J., Sammler, E., Luciano, M.S., Satake, W., Saunders‐Pullman, R., Sazci, A., Scherzer, C., Schrag, A., Schumacher‐Schuh, A., Sharma, M., Sidransky, E., Singleton, A.B., Petersen, M.S., Smolders, S., Spitz, M., Stefanis, L., Struhal, W., Sue, C., Swan, M., Swanberg, M., Taba, P., Taipa, R., Tan, M., Tan, A.H., Tan, E‐K, Tang, B., Tayebi, N., Thaler, A., Thomas, A., Toda, T., Toft, M., Torres, L., Tumas, V., Valente, E.M., Van Broeckhoven, C., Vecsei, L., Velez‐Pardo, C., Vidailhet, M., Warner, T.T., Williams‐Gray, C.H., Winkelmann, J., Woitalla, D., Wood, N.W., Wszolek, Z.K., Wu, R‐M, Wu, Y‐R, Xie, T., Yoshino, H., Zhang, B., and Zimprich, A.
Abstract: Talks on rare diseases in the field of neurology often start with a statement like this: “About 80% of all rare diseases have a neurologic manifestation and about 80% of those are genetic in origin.” Although these numbers probably represent more of an estimate than well‐documented evidence, rapidly advancing and cost‐effective sequencing technologies have led to the quickly growing identification of patients with hereditary neurological diseases...
Published: 2019

30. Using global team science to identify genetic parkinson's disease worldwide

Author: Vollstedt, E. -J., Kasten, M., Klein, C., Aasly, J., Adler, C., Ahmad-Annuar, A., Albanese, Alberto, Alcalay, R. N., Al-Mubarak, B., Alvarez, V., Andree-Munoz, B., Annesi, G., Appel-Cresswell, S., Arkadir, D., Armasu, S., Barber, T. R., Bardien, S., Barkhuizen, M., Barrett, M. J., Basak, A. N., Beach, T., Benitez, B. A., Berg, D., Bhatia, K., Binkofski, F., Blauwendraat, C., Bonifati, V., Borges, V., Bozi, M., Brice, A., Brighina, L., Brockmann, K., Brucke, T., Bruggemann, N., Camacho, M., Cardoso, F., Belin, A. C., Carr, J., Chan, P., Chang-Castello, J., Chase, B., Chen-Plotkin, A., Ju Chung, S., Cilia, R., Clarimon, J., Clark, L., Cornejo-Olivas, M., Corvol, J. -C., Cosentino, C., Cras, P., Crosiers, D., Damasio, J., Das, P., de Carvalho Aguiar, P., De Michele, G., De Rosa, A., Dieguez, E., Dorszewska, J., Erer, S., Ertan, S., Farrer, M., Fedotova, E., Ferese, R., Ferrarese, C., Ferraz, H., Fiala, O., Foroud, T., Friedman, A., Frigerio, R., Funayama, M., Gambardella, S., Garraux, G., Gatto, E. M., Genc, G., Giladi, N., Goldwurm, S., Gomez-Esteban, J. C., Gomez-Garre, P., Gorostidi, A., Grosset, D., Hanagasi, H., Hardy, J., Hassan, A., Hattori, N., Hauser, R. A., Hedera, P., Hentati, F., Hertz, J. M., Holton, J. L., Houlden, H., Hutz, M. H., Ikeuchi, T., Illarioshkin, S., Inca-Martinez, M., Infante, J., Jankovic, J., Jeon, B. S., Jesus, S., Jimenez-Del-Rio, M., Kaasinen, V., Kataoka, H., Kawakami, H., Kim, Y. J., Klivenyi, P., Koks, S., Konig, I. R., Kostic, V., Koziorowski, D., Kruger, R., Krygowska-Wajs, A., Kulisevsky, J., Lai, D., Lang, A., Ledoux, M., Lesage, S., Lim, S. -Y., Lin, C. -H., Lohmann, K., Lopera, F., Lopez, G., Lu, C. -S., Lynch, T., Machaczka, M., Madoev, H., Magalhaes, M., Majamaa, K., Maraganore, D., Marder, K., Markopoulou, K., Martikainen, M. H., Mata, I., Mazzetti, P., Mellick, G., Menendez-Gonzalez, M., Micheli, F., Mirelman, A., Mir, P., Morino, H., Morris, H., Munhoz, R. P., Naito, A., Olszewska, D. A., Ozelius, L. J., Padmanabhan, S., Paisan-Ruiz, C., Payami, H., Peluso, S., Petkovic, S., Petrucci, S., Pezzoli, G., Pimentel, M., Pirker, W., Pramstaller, P. P., Pulkes, T., Puschmann, A., Quattrone, A., Raggio, V., Ransmayr, G., Rieder, C., Riess, O., Rodriguez-Porcel, F., Rogaeva, E., Ross, O. A., Ruiz-Martinez, J., Sammler, E., San Luciano, M., Satake, W., Saunders-Pullman, R., Sazci, A., Scherzer, C., Schrag, A., Schumacher-Schuh, A., Sharma, M., Sidransky, E., Singleton, A. B., Petersen, M. S., Smolders, S., Spitz, M., Stefanis, L., Struhal, W., Sue, C. M., Swan, M., Swanberg, M., Taba, P., Taipa, R., Tan, M., Tan, A. H., Tan, E. -K., Tang, B., Tayebi, N., Thaler, A., Thomas, A., Toda, T., Toft, M., Torres, L., Tumas, V., Valente, E. M., Van Broeckhoven, C., Vecsei, L., Velez-Pardo, C., Vidailhet, M., Warner, T. T., Williams-Gray, C. H., Winkelmann, J., Woitalla, D., Wood, N. W., Wszolek, Z. K., Wu, R. -M., Wu, Y. -R., Xie, T., Yoshino, H., Zhang, B., Zimprich, A., Albanese A. (ORCID:0000-0002-5864-0006), Vollstedt, E. -J., Kasten, M., Klein, C., Aasly, J., Adler, C., Ahmad-Annuar, A., Albanese, Alberto, Alcalay, R. N., Al-Mubarak, B., Alvarez, V., Andree-Munoz, B., Annesi, G., Appel-Cresswell, S., Arkadir, D., Armasu, S., Barber, T. R., Bardien, S., Barkhuizen, M., Barrett, M. J., Basak, A. N., Beach, T., Benitez, B. A., Berg, D., Bhatia, K., Binkofski, F., Blauwendraat, C., Bonifati, V., Borges, V., Bozi, M., Brice, A., Brighina, L., Brockmann, K., Brucke, T., Bruggemann, N., Camacho, M., Cardoso, F., Belin, A. C., Carr, J., Chan, P., Chang-Castello, J., Chase, B., Chen-Plotkin, A., Ju Chung, S., Cilia, R., Clarimon, J., Clark, L., Cornejo-Olivas, M., Corvol, J. -C., Cosentino, C., Cras, P., Crosiers, D., Damasio, J., Das, P., de Carvalho Aguiar, P., De Michele, G., De Rosa, A., Dieguez, E., Dorszewska, J., Erer, S., Ertan, S., Farrer, M., Fedotova, E., Ferese, R., Ferrarese, C., Ferraz, H., Fiala, O., Foroud, T., Friedman, A., Frigerio, R., Funayama, M., Gambardella, S., Garraux, G., Gatto, E. M., Genc, G., Giladi, N., Goldwurm, S., Gomez-Esteban, J. C., Gomez-Garre, P., Gorostidi, A., Grosset, D., Hanagasi, H., Hardy, J., Hassan, A., Hattori, N., Hauser, R. A., Hedera, P., Hentati, F., Hertz, J. M., Holton, J. L., Houlden, H., Hutz, M. H., Ikeuchi, T., Illarioshkin, S., Inca-Martinez, M., Infante, J., Jankovic, J., Jeon, B. S., Jesus, S., Jimenez-Del-Rio, M., Kaasinen, V., Kataoka, H., Kawakami, H., Kim, Y. J., Klivenyi, P., Koks, S., Konig, I. R., Kostic, V., Koziorowski, D., Kruger, R., Krygowska-Wajs, A., Kulisevsky, J., Lai, D., Lang, A., Ledoux, M., Lesage, S., Lim, S. -Y., Lin, C. -H., Lohmann, K., Lopera, F., Lopez, G., Lu, C. -S., Lynch, T., Machaczka, M., Madoev, H., Magalhaes, M., Majamaa, K., Maraganore, D., Marder, K., Markopoulou, K., Martikainen, M. H., Mata, I., Mazzetti, P., Mellick, G., Menendez-Gonzalez, M., Micheli, F., Mirelman, A., Mir, P., Morino, H., Morris, H., Munhoz, R. P., Naito, A., Olszewska, D. A., Ozelius, L. J., Padmanabhan, S., Paisan-Ruiz, C., Payami, H., Peluso, S., Petkovic, S., Petrucci, S., Pezzoli, G., Pimentel, M., Pirker, W., Pramstaller, P. P., Pulkes, T., Puschmann, A., Quattrone, A., Raggio, V., Ransmayr, G., Rieder, C., Riess, O., Rodriguez-Porcel, F., Rogaeva, E., Ross, O. A., Ruiz-Martinez, J., Sammler, E., San Luciano, M., Satake, W., Saunders-Pullman, R., Sazci, A., Scherzer, C., Schrag, A., Schumacher-Schuh, A., Sharma, M., Sidransky, E., Singleton, A. B., Petersen, M. S., Smolders, S., Spitz, M., Stefanis, L., Struhal, W., Sue, C. M., Swan, M., Swanberg, M., Taba, P., Taipa, R., Tan, M., Tan, A. H., Tan, E. -K., Tang, B., Tayebi, N., Thaler, A., Thomas, A., Toda, T., Toft, M., Torres, L., Tumas, V., Valente, E. M., Van Broeckhoven, C., Vecsei, L., Velez-Pardo, C., Vidailhet, M., Warner, T. T., Williams-Gray, C. H., Winkelmann, J., Woitalla, D., Wood, N. W., Wszolek, Z. K., Wu, R. -M., Wu, Y. -R., Xie, T., Yoshino, H., Zhang, B., Zimprich, A., and Albanese A. (ORCID:0000-0002-5864-0006)
Abstract: Talks on rare diseases in the field of neurology often start with a statement like this: “About 80% of all rare diseases have a neurologic manifestation and about 80% of those are genetic in origin.” Although these numbers probably represent more of an estimate than well-documented evidence, rapidly advancing and cost-effective sequencing technologies have led to the quickly growing identification of patients with hereditary neurological diseases. Although the importance of genetics for diagnosis and genetic counseling is undisputed, the recent development of first genetargeted therapies entering clinical trial1,2 is adding an important new layer to the (re-)consideration of genetic testing in neurology. However, establishing accurate genotype– phenotype and genotype–treatment relationships requires large sample sizes. Systematic reviews can serve as instruments to combine information from several small samples, but unfortunately, this is often complicated by inconsistent and incomplete reporting of clinical and genetic data across studies. Thus, large multicenter approaches are necessary to systematically and uniformly characterize patients with genetic neurologic conditions and to eventually establish sizable clinical trial-ready cohorts.
Published: 2019

31. Campylobacter bacteremia: Clinical experience with three different blood culture systems at Mayo Clinic 1984–1990

Author: Kasten, M. J., Allerberger, F., and Anhalt, J. P.
Published: 1991
Full Text: View/download PDF

32. P339NEU1 increases monocyte and macrophage-mediated inflammation and may act as a potential modulator of atherosclerosis

Author: Ricke-Hoch, M, primary, Sieve, I, additional, Kasten, M, additional, Battmer, K, additional, Stapel, B, additional, Leisegang, M S, additional, Haverich, A, additional, Scherr, M, additional, and Hilfiker-Kleiner, D, additional
Published: 2018
Full Text: View/download PDF

33. Critical evaluation of DNA methylation markers for type-2-diabetes risk prediction

Author: Krause, C, additional, Sievert, H, additional, Grohs, M, additional, Geißler, C, additional, El Gammal, AT, additional, Wolter, S, additional, Lill, CM, additional, Krämer, UM, additional, Kasten, M, additional, Klein, C, additional, Brabant, G, additional, Mann, O, additional, Lehnert, H, additional, and Kirchner, H, additional
Published: 2018
Full Text: View/download PDF

34. Walter Benjamin on Charlie Chaplin. The Rehabilitation of the Allegorical in Modernity

Author: Kasten, M., Sneller, R., Visser, G., Mourenza, D., Kasten, M., Sneller, R., Visser, G., and Mourenza, D.
Abstract: Item does not contain fulltext
Published: 2018

35. An omics-based strategy using coenzyme Q10 in patients with Parkinson's disease: Design of a concept evaluation in a double-blind randomised placebo-controlled phase II study

Author: Heßler, N, Kasten, M, Berg, D, Brüggemann, N, Gasser, T, Krockenberger, K, Olbrich, D, Prasuhn, J, Klein, C, Ziegler, A, Heßler, N, Kasten, M, Berg, D, Brüggemann, N, Gasser, T, Krockenberger, K, Olbrich, D, Prasuhn, J, Klein, C, and Ziegler, A
Published: 2017

36. The Absolute Presupposition of Language: Agamben Reading Gadamer

Author: Heiden, G.J. van der, Kasten, M., Paul, H., Sneller, R., Kasten, M., Paul, H., and Sneller, R.
Subjects: The Project of a Hermeneutic Philosophy
Abstract: Item does not contain fulltext
Published: 2012

37. ATLAS FTK: Fast track trigger

Author: Anderson J, Andreani A, Andreazza A, Annovi A, Atkinson M, Auerbach B, Beretta M, Bevacqua V, Blair R, Blazey G, Bogdan M, Boveia A, Canelli F, Castegnaro A, Cavaliere V, Cervigni F, Chang P, Cheng Y, Citterio M, Crescioli F, Dell'Orso M, Drake G, Dunford M, Favareto A, Geer S, Giannetti P, Gruenendahl S, Li HL, Hoff J, Iizawa T, Jamieson O, Kapliy A, Kasten M, Kim YK, Kimura N, Lanza A, Liberali V, Liu T, Magalotti D, McCarn A, Melachrinos C, Meroni C, Mitani T, Murat P, Negri A, Neubauer M, Okumura Y, Penning B, Piendibene M, Proudfoot J, Roda C, Sacco I, Sakurai Y, Shochet M, Stabile A, Tang J, Tang F, Tompkins L, Tripiccione R, Tuggle J, Vercesi V, Verzocchi M, Volpi G, Webster J, Yorita K, Zhang J, S. Amerio, A. Andreani, A. Andreazza, A. Annovi, M. Beretta, V. Bevacqua, G. Blazey, M. Bogda, E. Bossini, A. Boveia, V. Cavaliere, F. Canelli, F. Cervigni, Y. Cheng, M. Citterio, F. Crescioli, M. Dell’Orso, G. Drake, M. Dunford, P. Giannetti, F. Giorgi, J. Hoff, A. Kapliy, M. Kasten, Y. K. Kim, N. Kimura, A. Lanza, V. Liberali, T. Liu, D. Magalotti, A. McCarn, C. Melachrinos, C. Meroni, A. Negri, M. Neubauer, B. Penning, M. Piendibene, J. Proudfoot, M. Rivag, C. Roda, F. Sabatini, I. Sacco, M. Shochet, A. Stabile, F. Tang, J. Tang, R. Tripiccione, Joseph Tuggle, V. Vercesi, M. Verzocchi, M. Villa, R. A. Vitillo, G. Volpi, J. Webster, J. Wu, K. Yorita, J. Zhang, FABBRI, LAURA, FRANCHINI, MATTEO, GIANNUZZI, FABIO, GIORGI, FILIPPO MARIA, LASAGNI MANGHI, FEDERICO, SBARRA, CARLA, VALENTINETTI, SARA, VILLA, MAURO, ZOCCOLI, ANTONIO, Anderson J, Andreani A, Andreazza A, Annovi A, Atkinson M, Auerbach B, Beretta M, Bevacqua V, Blair R, Blazey G, Bogdan M, Boveia A, Canelli F, Castegnaro A, Cavaliere V, Cervigni F, Chang P, Cheng Y, Citterio M, Crescioli F, Dell'Orso M, Drake G, Dunford M, Fabbri L, Favareto A, Franchini M, Geer S, Giannetti P, Giannuzzi F, Giorgi F, Gruenendahl S, Li HL, Hoff J, Iizawa T, Jamieson O, Kapliy A, Kasten M, Kim YK, Kimura N, Lanza A, Lasagni F, Liberali V, Liu T, Magalotti D, McCarn A, Melachrinos C, Meroni C, Mitani T, Murat P, Negri A, Neubauer M, Okumura Y, Penning B, Piendibene M, Proudfoot J, Roda C, Sacco I, Sakurai Y, Sbarra C, Shochet M, Stabile A, Tang J, Tang F, Tompkins L, Tripiccione R, Tuggle J, Valentinetti S, Vercesi V, Verzocchi M, Villa M, Volpi G, Webster J, Yorita K, Zhang J, Zoccoli A, S. Amerio, A. Andreani, A. Andreazza, A. Annovi, M. Beretta, V. Bevacqua, G. Blazey, M. Bogda, E. Bossini, A. Boveia, V. Cavaliere, F. Canelli, F. Cervigni, Y. Cheng, M. Citterio, F. Crescioli, M. Dell’Orso, G. Drake, M. Dunford, P. Giannetti, F. Giorgi, J. Hoff, A. Kapliy, M. Kasten, Y. K. Kim, N. Kimura, A. Lanza, V. Liberali, T. Liu, D. Magalotti, A. McCarn, C. Melachrino, C. Meroni, A. Negri, M. Neubauer, B. Penning, M. Piendibene, J. Proudfoot, M. Rivag, C. Roda, F. Sabatini, I. Sacco, M. Shochet, A. Stabile, F. Tang, J. Tang, R. Tripiccione, Joseph Tuggle, V. Vercesi, M. Verzocchi, M. Villa, R.A. Vitillo, G. Volpi, J. Webster, J. Wu, K. Yorita, and J. Zhang
Subjects: FTK, TRACKING, Physics::Instrumentation and Detectors, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, High Energy Physics::Experiment, ATLAS, ComputingMethodologies_COMPUTERGRAPHICS, TRIGGER
Abstract: A track reconstruction system for the trigger of the ATLAS detector at the Large Hadron Collider is described. The Fast Tracker is a highly parallel hardware system designed to operate at the Level-1 trigger output rate. It will provide high-quality tracks reconstructed over the entire inner detector by the start of processing in the Level-2 trigger. The system is based on associative memories for pattern recognition and fast FPGA’s for track reconstruction. Its design and expected performance under instantaneous luminosities up to 3×1034/cm2/s are discussed
Published: 2011

38. Aiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies

Author: Lerche, S., Heinzel, S., Alves, G.W., Barone, P., Behnke, S., Ben-Shlomo, Y., Berendse, H., Bloem, B.R., Burn, D., Dodel, R., Grosset, D.G., Hipp, G., Hu, M.T., Kasten, M., Kruger, R., Liepelt-Scarfone, I., Maetzler, W., Moccia, M., Mollenhauer, B., Oertel, W., Roeben, B., Walter, U., Wirdefeldt, K., Berg, D., Lerche, S., Heinzel, S., Alves, G.W., Barone, P., Behnke, S., Ben-Shlomo, Y., Berendse, H., Bloem, B.R., Burn, D., Dodel, R., Grosset, D.G., Hipp, G., Hu, M.T., Kasten, M., Kruger, R., Liepelt-Scarfone, I., Maetzler, W., Moccia, M., Mollenhauer, B., Oertel, W., Roeben, B., Walter, U., Wirdefeldt, K., and Berg, D.
Abstract: Contains fulltext : 168050.pdf (publisher's version ) (Open Access)
Published: 2016

39. Prodromal Markers in Parkinson's Disease: Limitations in Longitudinal Studies and Lessons Learned

Author: Heinzel, S., Roeben, B., Ben-Shlomo, Y., Lerche, S., Alves, G., Barone, P., Behnke, S., Berendse, H.W., Bloem, B.R., Burn, D., Dodel, R., Grosset, D.G., Hu, M., Kasten, M., Kruger, R., Moccia, M., Mollenhauer, B., Oertel, W., Suenkel, U., Walter, U., Wirdefeldt, K., Liepelt-Scarfone, I., Maetzler, W., Berg, D., Heinzel, S., Roeben, B., Ben-Shlomo, Y., Lerche, S., Alves, G., Barone, P., Behnke, S., Berendse, H.W., Bloem, B.R., Burn, D., Dodel, R., Grosset, D.G., Hu, M., Kasten, M., Kruger, R., Moccia, M., Mollenhauer, B., Oertel, W., Suenkel, U., Walter, U., Wirdefeldt, K., Liepelt-Scarfone, I., Maetzler, W., and Berg, D.
Abstract: Contains fulltext : 168070.pdf (publisher's version ) (Open Access), A growing body of evidence supports a prodromal neurodegenerative process preceding the clinical onset of Parkinson's disease (PD). Studies have identified several different prodromal markers that may have the potential to predict the conversion from healthy to clinical PD but use considerably different approaches. We systematically reviewed 35 longitudinal studies reporting prodromal PD features and evaluated the methodological quality across 10 different predefined domains. We found limitations in the following domains: PD diagnosis (57% of studies), prodromal marker assessments (51%), temporal information on prodromal markers or PD diagnosis (34%), generalizability of results (17%), statistical methods (accounting for at least age as confounder; 17%), study design (14%), and sample size (9%). However, no limitations regarding drop-out (or bias investigation), or report of inclusion/exclusion criteria or prodromal marker associations were revealed. Lessons learned from these limitations and additional aspects of current prodromal marker studies in PD are discussed to provide a basis for the evaluation of findings and the improvement of future research in prodromal PD. The observed heterogeneity of studies, limitations and analyses might be addressed in future longitudinal studies using a, yet to be established, modular minimal set of assessments improving comparability of findings and enabling data sharing and combined analyses across studies.
Published: 2016

40. Multi-Casing Well Integrity Inspection in Oil and Gas Wells

Author: Kasten, M.., additional, Mandal, S.., additional, Ross, W.., additional, Price, S.., additional, Plotnikov, Y.., additional, Ivan, A.., additional, Climent, H. C., additional, Nieters, E.., additional, Guida, R.., additional, and Dolinsky, S.., additional
Published: 2016
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41. The FTK: A Hardware Track Finder for the ATLAS Trigger

Author: Alison, J, Ancu, L, Anderson, J, Andreani, A, Andreazza, A, Annovi, A, Antonelli, M, Atkinson, M, Auerbach, B, Baines, J, Barberio, E, Beccherle, R, Beretta, M, Biesuz, N V, Blair, R, Blazey, G, Bogdan, M, Boveia, A, Britzger, D, Bryant, P, Burghgrave, B, Calderini, G, Cavaliere, V, Cavasinni, V, Chakraborty, D, Chang, P, Cheng, Y, Cipriani, R, Citraro, S, Citterio, M, Crescioli, F, Dell'Orso, M, Donati, S, Dondero, P, Drake, G, Gadomski, S, Gatta, M, Gentsos, C, Giannetti, P, Giulini, M, Gkaitatzis, S, Howarth, J W, Iizawa, T, Kapliy, A, Kasten, M, Kim, Y K, Kimura, N, Klimkovich, T, Kordas, K, Korikawa, T, Krizka, K, Kubota, T, Lanza, A, Lasagni, F, Liberali, V, Li, H L, Love, J, Luciano, P, Luongo, C, Magalotti, D, Melachrinos, C, Meroni, C, Mitani, T, Negri, A, Neroutsos, P, Neubauer, M, Nikolaidis, S, Okumura, Y, Pandini, C, Penning, B, Petridou, C, Piendibene, M, Proudfoot, J, Rados, P, Roda, C, Rossi, E, Sakurai, Y, Sampsonidis, D, Sampsonidou, D, Schmitt, S, Schoening, A, Shochet, M, Shojaii, S, Soltveit, H, Sotiropoulou, C L, Stabile, A, Tang, F, Testa, M, Tompkins, L, Vercesi, V, Villa, M, Volpi, G, Webster, J, Wu, X, Yorita, K, Yurkewicz, A, Zeng, J C, and Zhang, J
Subjects: Particle Physics - Experiment
Abstract: The ATLAS experiment trigger system is designed to reduce the event rate, at the LHC design luminosity of 1034 cm-2 s-1, from the nominal bunch crossing rate of 40 MHz to less than 1 kHz for permanent storage. During Run 1, the LHC has performed exceptionally well, routinely exceeding the design luminosity. From 2015 the LHC is due to operate with higher still luminosities. This will place a significant load on the High Level Trigger system, both due to the need for more sophisticated algorithms to reject background, and from the larger data volumes that will need to be processed. The Fast TracKer is a hardware upgrade for Run 2, consisting of a custom electronics system that will operate at the full rate for Level-1 accepted events of 100 kHz and provide high quality tracks at the beginning of processing in the High Level Trigger. This will perform track reconstruction using hardware with massive parallelism using associative memories and FPGAs. The availability of the full tracking information will enable robust trigger selection within the affordable latency available at the High Level Trigger, with only a limited degradation in performance arising from the additional pileup from higher luminosity running.
Published: 2014

42. Interference of cartilage surface with interaction of granulocyte elastase with α1-proteinase inhibitor: An in vitro model of enzyme inhibition in the joint space

Author: Burkhardt, H., Kasten, M., Rauls, S., and Rehkopf, E.
Published: 1987
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43. Whispering dysphonia (DYT4 dystonia) is caused by a mutation in the TUBB4 gene

Author: Lohmann, K., Wilcox, R.A., Winkler, S., Ramirez, A., Rakovic, A., Park, J.S., Arns, B., Lohnau, T., Groen, J., Kasten, M., Bruggemann, N., Hagenah, J., Schmidt, A., Kaiser, F.J., Kumar, K.R., Zschiedrich, K., Alvarez-Fischer, D., Altenmuller, E., Ferbert, A., Lang, A.E., Munchau, A., Kostic, V., Simonyan, K., Agzarian, M., Ozelius, L.J., Langeveld, A.P.M., Sue, C.M., Tijssen, M.A.J., Klein, C., and Other departments
Subjects: Family Health, Male, PRIMARY TORSION DYSTONIA, Voice Disorders, Genetic Linkage, DNA Mutational Analysis, Dystonia Musculorum Deformans, Magnetic Resonance Imaging, Severity of Illness Index, Article, Imaging, Three-Dimensional, Tubulin, BETA-TUBULIN ISOTYPES, Mutation, otorhinolaryngologic diseases, LINKAGE, Humans, Female, Genetic Predisposition to Disease, NUCLEAR-ENVELOPE, Chromosomes, Human, Pair 19, Follow-Up Studies
Abstract: Objective A study was undertaken to identify the gene underlying DYT4 dystonia, a dominantly inherited form of spasmodic dysphonia combined with other focal or generalized dystonia and a characteristic facies and body habitus, in an Australian family. Methods Genome-wide linkage analysis was carried out in 14 family members followed by genome sequencing in 2 individuals. The index patient underwent a detailed neurological follow-up examination, including electrophysiological studies and magnetic resonance imaging scanning. Biopsies of the skin and olfactory mucosa were obtained, and expression levels of TUBB4 mRNA were determined by quantitative real-time polymerase chain reaction in 3 different cell types. All exons of TUBB4 were screened for mutations in 394 unrelated dystonia patients. Results The disease-causing gene was mapped to a 23cM region on chromosome 19p13.3-p13.2 with a maximum multipoint LOD score of 5.338 at markers D9S427 and D9S1034. Genome sequencing revealed a missense variant in the TUBB4 (tubulin beta-4; Arg2Gly) gene as the likely cause of disease. Sequencing of TUBB4 in 394 unrelated dystonia patients revealed another missense variant (Ala271Thr) in a familial case of segmental dystonia with spasmodic dysphonia. mRNA expression studies demonstrated significantly reduced levels of mutant TUBB4 mRNA in different cell types from a heterozygous Arg2Gly mutation carrier compared to controls. Interpretation A mutation in TUBB4 causes DYT4 dystonia in this Australian family with so-called whispering dysphonia, and other mutations in TUBB4 may contribute to spasmodic dysphonia. Given that TUBB4 is a neuronally expressed tubulin, our results imply abnormal microtubule function as a novel mechanism in the pathophysiology of dystonia. Ann Neurol 2013;73:537-545
Published: 2013

44. Gadamer and the end of art

Author: Evink, C.E., Kasten, M., Paul, H., Sneller, R., and History of Philosophy
Subjects: ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries)
Published: 2012

45. Fünf-Jahres-Nachuntersuchung von Parkinsonpatienten mit und ohne Parkin-Mutationen

Author: Kasten, M, Hagenah, J, Hauenschild, S, Jacobs, H, Kabakci, K, Pramstaller, P, Vieregge, P, and Klein, C
Published: 2024
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46. Metaanalyse zu klinischen und demographischen Eigenschaften von homozygoten und heterozygoten PINK1 Mutationsträgern

Author: Kasten, M, Weichert, C, Lohmann, K, and Klein, C
Published: 2024
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47. Hyperechogenität der Substantia nigra bei Parkin-assoziertem Parkinsonismus; Korrelation des klinischen und genetischen Status

Author: Hagenah, JM, König, IR, Hedrich, K, Kasten, M, Pramstaller, PP, Becker, B, Klein, C, and Seidel, G
Published: 2024
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48. Beeinträchtigung der Geruchs- und Farbwahrnehmung bei genetischen und nicht genetischen Parkinson-Syndromen

Author: Tadic, V, Kertelge, L, Brüggemann, N, Schmidt, A, Wisse, C, Drude, L, van der Vegt, J, Schneider, SA, Siebner, HR, Lohmann, K, Buhmann, C, Hagenah, J, Klein, C, and Kasten, M
Published: 2024
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49. Design of a hardware track finder (Fast Tracker) for the ATLAS trigger

Author: Cavaliere, V., primary, Adelman, J., additional, Albicocco, P., additional, Alison, J., additional, Ancu, L.S., additional, Anderson, J., additional, Andari, N., additional, Andreani, A., additional, Andreazza, A., additional, Annovi, A., additional, Antonelli, M., additional, Asbah, N., additional, Atkinson, M., additional, Baines, J., additional, Barberio, E., additional, Beccherle, R., additional, Beretta, M., additional, Bertolucci, F., additional, Biesuz, N.V., additional, Blair, R., additional, Bogdan, M., additional, Boveia, A., additional, Britzger, D., additional, Bryant, P., additional, Burghgrave, B., additional, Calderini, G., additional, Camplani, A., additional, Cavasinni, V., additional, Chakraborty, D., additional, Chang, P., additional, Cheng, Y., additional, Citraro, S., additional, Citterio, M., additional, Crescioli, F., additional, Dawe, N., additional, Dell'Orso, M., additional, Donati, S., additional, Dondero, P., additional, Drake, G., additional, Gadomski, S., additional, Gatta, M., additional, Gentsos, C., additional, Giannetti, P., additional, Gkaitatzis, S., additional, Gramling, J., additional, Howarth, J.W., additional, Iizawa, T., additional, Ilic, N., additional, Jiang, Z., additional, Kaji, T., additional, Kasten, M., additional, Kawaguchi, Y., additional, Kim, Y.K., additional, Kimura, N., additional, Klimkovich, T., additional, Kolb, M., additional, Kordas, K, additional, Krizka, K., additional, Kubota, T., additional, Lanza, A., additional, Li, H.L., additional, Liberali, V., additional, Lisovyi, M., additional, Liu, L., additional, Love, J., additional, Luciano, P., additional, Luongo, C., additional, Magalotti, D., additional, Maznas, I., additional, Meroni, C., additional, Mitani, T., additional, Nasimi, H., additional, Negri, A., additional, Neroutsos, P., additional, Neubauer, M., additional, Nikolaidis, S., additional, Okumura, Y., additional, Pandini, C., additional, Petridou, C., additional, Piendibene, M., additional, Proudfoot, J., additional, Rados, P., additional, Roda, C., additional, Rossi, E., additional, Sakurai, Y., additional, Sampsonidis, D., additional, Saxon, J., additional, Schmitt, S., additional, Schoening, A., additional, Shochet, M., additional, Shojaii, S., additional, Soltveit, H., additional, Sotiropoulou, C.L., additional, Stabile, A., additional, Swiatlowski, M., additional, Tang, F., additional, Taylor, P.T., additional, Testa, M., additional, Tompkins, L., additional, Vercesi, V., additional, Volpi, G., additional, Wang, R., additional, Watari, R., additional, Webster, J., additional, Wu, X., additional, Yorita, K., additional, Yurkewicz, A., additional, Zeng, J.C., additional, Zhang, J., additional, and Zou, R., additional
Published: 2016
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50. Methods in Neuroepidemiology Characterization of European Longitudinal Cohort Studies in Parkinson's Disease - Report of the JPND Working Group BioLoC-PD

Author: Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) [research center], Lerche, S., Liepelt-Scarfone, I., Alves, G., Barone, P., Behnke, S., Ben-Shlomo, Y., Berendse, H., Burn, D., Dodel, R., Grosset, D., Heinzel, S., Hu, M., Kasten, M., Krüger, Rejko, Maetzler, W., Moccia, M., Mollenhauer, B., Oertel, W., Roeben, B., Sunkel, U., Walter, U., Wirdefeldt, K., Berg, D., Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) [research center], Lerche, S., Liepelt-Scarfone, I., Alves, G., Barone, P., Behnke, S., Ben-Shlomo, Y., Berendse, H., Burn, D., Dodel, R., Grosset, D., Heinzel, S., Hu, M., Kasten, M., Krüger, Rejko, Maetzler, W., Moccia, M., Mollenhauer, B., Oertel, W., Roeben, B., Sunkel, U., Walter, U., Wirdefeldt, K., and Berg, D.
Abstract: BACKGROUND: Enormous effort is being put into the identification and characterization of symptoms that may be used as predictive and progression markers in Parkinson's disease (PD). An impressive number of PD patients and individuals at risk for or in the prodromal stage of PD are currently followed in longitudinal studies; however, there does not exist an overview on the kind of markers evaluated and the assessments used. METHODS: Information on the design, sample size, evaluated markers and assessments of 21 studies of the Joint Programme - Neurodegenerative Disease Research BioLoC-PD working group were collected by questionnaire. The studies were classified into at risk/prodromal or clinical PD cohorts. The assessments were grouped into quantitative assessments, investigator-rated assessments, investigator interviews, patient-rated questionnaires and caregiver-rated questionnaires. RESULTS: Compilation of these data revealed an interesting consensus on evaluated markers, but there was an enormous variability of assessments. Furthermore, there is a remarkable similarity in the markers assessed and evaluation methods applied in the risk/prodromal and clinical PD cohorts. CONCLUSIONS: The inventory of the longitudinal cohorts that are part of the BioLoC-PD consortium reveals that there is a growing consensus on the markers that should be assessed in longitudinal cohort studies in PD. However, controversy still exists on the specific type of assessment. To allow comparison of data and common analyses it will be essential to harmonize scales and assessment outcomes.
Published: 2015

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