1. A Novel Hemodynamic Index Characterizing Mitral Regurgitation Undergoing Transcatheter Edge-to-Edge Repair
- Author
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Antonio Maria Leone, MD, PhD, Federico Di Giusto, MD, Katya Lucarelli, MD, PhD, Andrea Vicerè, MD, Gianluca Anastasia, MD, Domenico Galante, MD, Edoardo Petrolati, MD, Francesco Bianchini, MD, Francesco Burzotta, MD, Cristina Aurigemma, MD, Antonella Lombardo, MD, Gabriella Locorotondo, MD, Francesca Graziani, MD, Vito Casamassima, MD, Massimo Grimaldi, MD, PhD, and Carlo Trani, MD
- Subjects
invasive hemodynamic monitoring ,mitral regurgitation ,mitral valve ,transcatheter mitral valve edge-to-edge repair ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Background: Hemodynamic impact of residual mitral regurgitation (MR) after transcatheter edge-to-edge repair (TEER) is not always univocally measured by transesophageal echocardiographic (TEE) assessment alone. When analyzing TEER procedure result, operators often encounter discrepancy between TEE guidance and invasive hemodynamic monitoring. Objectives: This study sought to investigate the role of invasive hemodynamic monitoring during mitral valve TEER procedure on top of TEE guidance. Methods: We analyzed 78 patients with moderate-to-severe or severe MR who underwent TEER. Mitral pulse pressure fraction (MPF) was extracted from intraprocedural continuous left atrial pressure monitoring. Twenty-three patients with the same grade of MR not undergoing TEER were included as a control group. At follow-up, clinical and functional status in the majority of patients undergoing TEER were reassessed by NYHA classification and the 12-item Kansas City Cardiomyopathy Questionnaire (KCCQ). Results: TEER significantly reduced MR burden on both TEE guidance and invasive hemodynamic monitoring. Post-TEER MPF was significantly reduced compared to both pre-TEER setting (P
- Published
- 2024
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