210 results on '"Kaysen D"'
Search Results
2. Interventions to treat posttraumatic stress disorder in partnership with primary care: A review of feasibility and large randomized controlled studies
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Hoeft, T.J., Stephens, K.A., Vannoy, S.D., Unützer, J., and Kaysen, D.
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- 2019
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3. The impact of Cognitive Processing Therapy on stigma among survivors of sexual violence in eastern Democratic Republic of Congo: results from a cluster randomized controlled trial
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Murray, S. M., Augustinavicius, J., Kaysen, D., Rao, D., Murray, L. K., Wachter, K., Annan, J., Falb, K., Bolton, P., and Bass, J. K.
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- 2018
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4. OUTCOMES OF AN RCT COMPARING TWO COPING SKILLS AMONG DUALLY DIAGNOSED INDIVIDUALS WITH ALCOHOL DEPENDENCE AND PTSD: 200
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Simpson, T. L., Stappenbeck, C. A., Luterek, J. A., Rosenthal, C. F., Gurrad, B., and Kaysen, D.
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- 2015
5. IMPLICIT AND EXPLICIT ALCOHOL COGNITIONS PREDICT ALCOHOL OUTCOMES PROSPECTIVELY: 115
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Lindgren, K. P., Neighbors, C., Ramirez, J., Gasser, M. L., Norris, J., Kaysen, D., Teachman, B., and Wiers, R. W.
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- 2015
6. 067 AN EVENT LEVEL EVALUATION OF THE INTERPLAY BETWEEN PTSD SYMPTOMS AND ALCOHOL CONSUMPTION AMONG INDIVIDUALS WITH COMORBID PTSD AND ALCOHOL DEPENDENCE
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Simpson, T. L., Stappenbeck, C. A., Luterek, J. A., Lehavot, K., and Kaysen, D. L.
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- 2013
7. EVERY NIGHT IS LADIES NIGHT: COMMUNITY INVOLVEMENT, DRINKING CONTEXT, AND COLLEGE STATUS IN RELATION TO DRINKING BEHAVIOR IN SEXUAL MINORITY WOMEN: 128
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Lee, C. M., Kaysen, D. L., Lewis, M. A., and Blayney, J. A.
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- 2012
8. USING SOCIAL NETWORKING SITES FOR PROJECT RECRUITMENT: REACHING HARD TO REACH POPULATIONS: 124
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Kilmer, J. R., Kaysen, D. L., and Lewis, M. A.
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- 2011
9. DRINKING MOTIVES, ALCOHOL-RELATED NEGATIVE CONSEQUENCES, AND PTSD IN FEMALE COLLEGE STUDENTS: 189
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Kaysen, D., Lee, C., Lindgren, K., and Desai, S.
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- 2010
10. PTSD AND ALCOHOL USE IN FEMALE COLLEGE STUDENTS: A DAILY PROCESS APPROACH TO THE SELF-MEDICATION HYPOTHESIS: 197
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Kaysen, D., Atkins, D., Lee, C. M., Lewis, M. A., Rees, M., and Desai, S.
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- 2009
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11. AN EXAMINATION OF THE CONTRIBUTING ROLES OF PTSD SYMPTOMS AND GENDER ON THE TRAUMATIC EVENT AND SUBSTANCE USE RELATIONSHIP: 898
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Kaysen, D., Lee, C., Kilmer, J., and Rees, M.
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- 2008
12. WHO IS LEADING THE DANCE? PTSD, AND CHANGES IN DRINKING IN FEMALE CRIME VICTIMS: 897
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Kaysen, D., Lee, C. M., Lindgren, K. P., Dillworth, T. M., and Simpson, T. S.
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- 2007
13. Developing an integrated intervention to address intimate partner violence and psychological distress in Congolese refugee women in Tanzania
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Greene, MC, Rees, S ; https://orcid.org/0000-0003-2845-6547, Likindikoki, S, Bonz, AG, Joscelyne, A, Kaysen, D, Nixon, RDV, Njau, T, Tankink, MTA, Tiwari, A, Ventevogel, P, Mbwambo, JKK, Tol, WA, Greene, MC, Rees, S ; https://orcid.org/0000-0003-2845-6547, Likindikoki, S, Bonz, AG, Joscelyne, A, Kaysen, D, Nixon, RDV, Njau, T, Tankink, MTA, Tiwari, A, Ventevogel, P, Mbwambo, JKK, and Tol, WA
- Abstract
Background: Multi-sectoral, integrated interventions have long been recommended for addressing mental health and its social determinants (e.g., gender-based violence) in settings of ongoing adversity. We developed an integrated health and protection intervention to reduce psychological distress and intimate partner violence (IPV), and tested its delivery by lay facilitators in a low-resource refugee setting. Methods: Formative research to develop the intervention consisted of a structured desk review, consultation with experts and local stakeholders (refugee incentive workers, representatives of humanitarian agencies, and clinical experts), and qualitative interviews (40 free list interviews with refugees, 15 key informant interviews). Given existing efforts by humanitarian agencies to prevent gender-based violence in this particular refugee camp, including with (potential) perpetrators, we focused on a complementary effort to develop an integrated intervention with potential to reduce IPV and associated mental health impacts with female IPV survivors. We enrolled Congolese refugee women with elevated psychological distress and past-year histories of IPV (n = 60) who received the intervention delivered by trained and supervised lay refugee facilitators. Relevance, feasibility and acceptability of the intervention were evaluated through quantitative and qualitative interviews with participants. We assessed instrument test-retest reliability (n = 24), inter-rater reliability (n = 5 interviews), internal consistency, and construct validity (n = 60). Results: We designed an 8-session intervention, termed Nguvu ('strength'), incorporating brief Cognitive Processing Therapy (focused on helping clients obtaining skills to overcome negative thoughts and self-perceptions and gain control over the impact these have on their lives) and Advocacy Counseling (focused on increasing autonomy, empowerment and strengthening linkages to community supports). On average, participants at
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- 2019
14. Emotional numbing symptoms linked to alcohol misuse in OEF/OIF vets
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Jakupcak, M., primary, Tull, M. T., additional, McDermott, M. J., additional, Kaysen, D., additional, Hunt, S., additional, and Simpson, T., additional
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- 2010
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15. PTSD symptoms, substance use, and vipassana meditation among incarcerated individuals
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Simpson, T. L., primary, Kaysen, D., additional, Bowen, S., additional, MacPherson, L. M., additional, Chawla, N., additional, Blume, A., additional, Marlatt, G. A., additional, and Larimer, M., additional
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- 2007
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16. Cerebral MRI of human brain development: Ages 4–18
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Giedd, J.N., primary, Castellanos, F.X., additional, Rajapakse, J.C., additional, Kaysen, D., additional, Vaituzis, A.C., additional, Vauss, Y.C., additional, Hamburger, S.D., additional, and Rapoport, J.L., additional
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- 1995
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17. Quantitative magnetic resonance imaging of human brain development: ages 4–18
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Giedd, J.N., primary, Castellanos, F.X., additional, Kozuch, P., additional, Casey, B.J., additional, Kaysen, D., additional, King, A.C., additional, Hamburger, S.D., additional, and Rapoport, J.L., additional
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- 1994
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18. Childhood-Onset Schizophrenia: An NIMH Study in Progress
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Gordon, C. T., primary, Frazier, J. A., additional, McKenna, K., additional, Giedd, J., additional, Zametkin, A., additional, Kaysen, D., additional, Albus, K. E., additional, Rapoport, J. L., additional, Zahn, T., additional, Hong, W., additional, and Hommer, D., additional
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- 1994
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19. Raytheon/SSSCO Oceanographic SWATH Ship Design.
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Lang, T., Becker, N., Kaysen, D., and Price, K.
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- 1982
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20. Posttraumatic stress disorder, alcohol use, and physical health concerns.
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Kaysen D, Pantalone DW, Chawla N, Lindgren KP, Clum GA, Lee C, and Resick PA
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POST-traumatic stress disorder , *NEUROSES , *PSYCHOLOGICAL stress , *TRAUMATIC neuroses , *PHYSIOLOGICAL effects of alcohol - Abstract
PTSD is a risk factor for alcohol problems and both in turn have been independently associated with increased health problems. However, it is unclear whether alcohol use moderates the relationship between PTSD and health. Participants were battered women ( N = 336) recruited from local domestic violence shelters and non-shelter victim-assistance agencies. A 2 (PTSD diagnosis) x 3 (abstainer, infrequent/light, regular/heavy drinking) ANCOVA was conducted, with injuries and length of abuse as covariates and health concerns as the dependent variable. Main effects for PTSD and alcohol use were significant but not the interaction. Women with PTSD reported the greatest number of health concerns. Women who abstained from drinking and those who drank regularly/heavily reported more health concerns than the infrequent/light drinkers. Health concerns associated with PTSD do not appear to be due to problem drinking. In addition, infrequent/light drinking, even for women with PTSD, may be associated with fewer health concerns. [ABSTRACT FROM AUTHOR]
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- 2008
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21. Living in danger: the impact of chronic traumatization and the traumatic context on posttraumatic stress disorder.
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Kaysen D, Resick PA, and Wise D
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In this article on the effects of chronic traumatization, research is reviewed regarding the association between chronicity of traumatization and posttraumatic stress disorder (PTSD) symptomatology. The contribution of the broader traumatic context to PTSD symptomatology is also examined. This review focuses on three populations: combat veterans, child sexual abuse survivors, and survivors of domestic violence. The challenges of defining chronicity of a traumatic event and traumatic context are addressed. Finally, suggestions for future directions are provided. [ABSTRACT FROM AUTHOR]
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- 2003
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22. A quantitative MRI study of the corpus callosum in children and adolescents
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Giedd, J. N., Rumsey, J. M., Castellanos, F. X., Rajapakse, J. C., Kaysen, D., Vaituzis, A. C., Vauss, Y. C., Hamburger, S. D., and Rapoport, J. L.
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- 1996
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23. Sensorimotor Gating in Boys with Tourette's Syndrome and ADHD: Preliminary Results
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Castellanos, F. Xavier, Fine, E. J., Kaysen, D., Marsh, W. L., Rapoport, J. L., and Hallett, M.
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- 1996
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24. Quantitative magnetic resonance imaging of human brain development: ages 4-18.
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Giedd, J N, Snell, J W, Lange, N, Rajapakse, J C, Casey, B J, Kozuch, P L, Vaituzis, A C, Vauss, Y C, Hamburger, S D, Kaysen, D, and Rapoport, J L
- Abstract
Brain magnetic resonance images (MRI) of 104 healthy children and adolescents, age 4-18, showed significant effects of age and gender on brain morphometry. Males had larger cerebral (9%) and cerebellar (8%) volumes (P < 0.0001 and P = 0.008, respectively), which remained significant even after correction for height and weight. After adjusting for cerebral size, the putamen and globus pallidus remained larger in males, while relative caudate size was larger in females. Neither cerebral nor cerebellar volume changed significantly across this age range. Lateral ventricular volume increased significantly in males (trend for females), with males showing an increase in slope after age 11. In males only, caudate and putamen decrease with age (P = 0.007 and 0.05, respectively). The left lateral ventricles and putamen were significantly greater than the right (P = 0.01 and 0.001, respectively). In contrast, the cerebral hemispheres and caudate showed a highly consistent right-greater-than-left asymmetry (P < 0.0001 for both). All volumes demonstrated a high degree of variability. These findings highlight gender-specific maturational changes of the developing brain and the need for large gender-matched samples in pediatric neuropsychiatric studies.
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- 1996
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25. Sydenham's chorea: Magnetic resonance imaging of the basal ganglia
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Giedd, J. N., Rapoport, J. L., Kruesi, M. J. P., Parker, C., Schapiro, M. B., Allen, A. J., Leonard, H. L., Kaysen, D., Dickstein, D. P., Marsh, W. L., patricia kozuch, Vaituzis, A. C., Hamburger, S. D., and Swedo, S. E.
26. Quantitative magnetic resonance imaging of human brain development: Ages 4-18
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Giedd, J. N., Snell, J. W., Lange, N., Jagath Rajapakse, Casey, B. J., Kozuch, P. L., Vaituzis, A. C., Vauss, Y. C., Hamburger, S. D., Kaysen, D., and Rapoport, J. L.
27. Raytheon/SSSCO Oceanographic SWATH Ship Design
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Lang, T., primary, Becker, N., additional, Kaysen, D., additional, and Price, K., additional
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- 1982
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28. Sydenham's chorea
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Giedd, J.N., Rapoport, J.L., Kruesi, M.J.P., Parker, C., Schapiro, M.B., Allen, A.J., Leonard, H.L., Kaysen, D., Dickstein, D.P., Marsh, W.L., Kozuch, P.L., Hamburger, S.D., and Swedo, S.E.
- Abstract
Analysis of cerebral magnetic resonance images of 24 subjects with Sydenham's chorea and 48 age-, height-, weight-, gender-, and handedness-matched controls demonstrated increased sizes of the caudate, putamen, and globus pallidus in the Sydenham's chorea group. In contrast, neither total cerebral, prefrontal, or midfrontal volumes or thalamic area were increased. These results indicate the selective involvement of the basal ganglia in Sydenham's chorea.
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- 1995
29. The predictive association between social support, communal mastery, and response to culturally adapted cognitive processing therapy among Native American women.
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van Stolk-Cooke K, Brier ZMF, Pearson C, Price M, and Kaysen D
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- Humans, Female, Adult, Middle Aged, Resilience, Psychological, Indians, North American psychology, Alaska Natives psychology, Young Adult, Culturally Competent Care, Treatment Outcome, Stress Disorders, Post-Traumatic therapy, Stress Disorders, Post-Traumatic psychology, Social Support, Cognitive Behavioral Therapy methods
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Though social support (SS) and communal mastery (CM) are resilience factors among American Indian and Alaska Natives (AIAN), they have not been examined as trauma treatment predictors in this at-risk group. This study evaluated whether SS and CM were associated with improved treatment response in a sample of 73 AIAN women with posttraumatic stress disorder (PTSD) symptoms. Participants received culturally adapted CPT and were assessed for PTSD, CM, and SS. Data were analyzed using linear mixed-effects models. SS predicted improved PTSD, β = -.16, SE = .05, p = .003, and mental health, β = .16, SE = .05, p = .005, but not physical health. CM predicted improved PTSD, β = -.93, SE = .34, p = .008; mental health, β = .90, SE = .36, p = .013; and physical health, β = .95, SE = .31, p = .003. In a combined model, SS predicted improvements in PTSD, β = -.15, SE = .04, p < .001, and mental health, β = .12, SE = .06, p = .037, whereas CM did not. CM predicted improved physical health, β = 1.04, SE = .33, p = .003, whereas SS did not. Results highlight the benefits of SS and CM in trauma treatment outcomes for AIAN women, consistent with prior work, and further underscore the differential role of SS versus CM on mental versus physical health. Future work should explore how orientation to close and communal-level relationships may inform the protective benefits of social resources among AIAN., (© 2024 International Society for Traumatic Stress Studies.)
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- 2025
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30. A randomized controlled trial testing theory-driven enhancements to increase the efficacy of and engagement in a brief cognitive-behavioural therapy text-message intervention for co-occurring posttraumatic stress disorder symptoms and alcohol misuse.
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Bedard-Gilligan M, Lindgren K, Dworkin E, Tristao T, Kaysen D, and Rhew I
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- Humans, Adult, Male, Female, Psychotherapy, Brief methods, Treatment Outcome, Middle Aged, Stress Disorders, Post-Traumatic therapy, Stress Disorders, Post-Traumatic psychology, Cognitive Behavioral Therapy methods, Alcoholism therapy, Alcoholism psychology, Text Messaging
- Abstract
Objective: Engaging individuals with co-occurring posttraumatic stress disorder (PTSD) and alcohol misuse (AM) in effective treatments is difficult. Brief, self-directed approaches that deliver empirically supported intervention techniques, such as cognitive-behavioural therapy (CBT) strategies, via technology may be effective and easier-to-access alternatives to traditional in-person therapy approaches for PTSD + AM. This paper describes the protocol for an intervention development study (NCT05372042) that evaluates a text-message intervention combining CBT texts with techniques from cognitive psychology (message framing) and social psychology (growth mindsets) for treatment of PTSD + AM., Method: The study uses a 3 (message framing: gain vs. loss vs. no framing) × 2 (mindset: growth mindsets vs. not) factorial design to test enhancements to CBT texts. Individuals age 18+, who report symptoms of PTSD and AM, will be recruited to participate. Participants will complete screening, verification, and baseline measures. They will be randomized to condition and receive 3 text messages per week for 4 weeks. Participants will be assessed at post-, 1-, and 3-month follow-up., Results: Analyses will evaluate whether framing and growth mindsets enhance the efficacy of CBT texts. A priori decision rules will be applied to select the intervention condition that is both the most effective and the simplest, which will be tested in a follow-up randomized controlled trial., Conclusions: This study will identify the simplest, most efficacious CBT intervention for PTSD + AM. Its use of cognitive and social psychology-based enhancement and of a factorial decision can serve as examples of how to enhance and increase engagement in brief, self-directed CBT interventions., (© 2024 British Psychological Society.)
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- 2025
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31. Mental health care-seeking and barriers: a cross-sectional study of an urban Latinx community.
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Newberry JA, Gimenez MA, Gunturkun F, Villa E, Maldonado M, Gonzalez D, Garcia G, Espinosa PR, Hedlin H, and Kaysen D
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- Humans, Cross-Sectional Studies, Female, Male, Adult, Middle Aged, Young Adult, Adolescent, Mental Disorders therapy, Mental Disorders ethnology, Aged, Hispanic or Latino statistics & numerical data, Hispanic or Latino psychology, Health Services Accessibility statistics & numerical data, Patient Acceptance of Health Care statistics & numerical data, Patient Acceptance of Health Care ethnology, Patient Acceptance of Health Care psychology, Mental Health Services statistics & numerical data, Urban Population statistics & numerical data
- Abstract
Background: The Latinx community faces an increasing amount of mental health challenges and disparities in care. While the contributing factors are complex, there are likely potential barriers related to connecting with mental health support and accessing care that can be addressed., Methods: To investigate barriers in connecting to mental health care, we conducted a cross-sectional survey of mental health service use and barriers in an urban community with a primarily Hispanic/Latinx ethnicity using a modified random walk approach for door-to-door data collection with a two-cluster sampling frame. Survey included questions on socio-demographic, mental health status, desire and attempt to seek care, and the Barriers to Access to Care Evaluation. Shapley additive explanation (SHAP) identified impactful barriers and demographic characteristics. Our primary outcome was the number of respondents who saw a professional in the past 12 months and the key determinants that enabled their successful connection. Secondary outcomes were people with poor mental health who had wanted or tried to seek any source of mental health support., Results: Of the 1004 respondents enrolled, 70.5% were foreign born; 63.4% were women. In the past 12 months, 23.8% of respondents wanted to connect with mental health care; 15.5% tried to connect, and only 11.7% successfully connected to mental health services. The two most cited barriers had the highest SHAP values: concerns about treatments available (65%) and financial costs (62.7%). Additional barriers with high SHAP values: being seen as weak and having no one to help them find care. Of demographic characteristics, age had the highest SHAP values., Conclusion: In a community with a high density of Latinx immigrants, just under half of respondents wanting mental health care successfully connected. Perceived informational, financial, and stigma-related barriers impacted the likelihood to connect with mental health care. These factors should be considered when designing programs and interventions to improve mental health care access and services in the Latinx community., (© 2024. The Author(s).)
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- 2024
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32. Using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework to evaluate the written exposure therapy training program in the Veterans Health Administration.
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LoSavio ST, Worley CB, Walser RD, Kaysen D, Rosen CS, and Wiltsey Stirman S
- Abstract
The Veterans Health Administration (VHA) has rolled out evidence-based psychotherapies (EBPs) for posttraumatic stress disorder (PTSD); however, reach has remained low, and there is a need for briefer interventions. The National Center for PTSD conducted a facilitated learning collaborative to train clinicians and support VHA PTSD teams in their adoption of an emerging best practice, written exposure therapy (WET). Guided by the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) evaluation framework, the present study utilized longitudinal data from 178 clinicians and 556 patients across seven training cohorts to evaluate key clinical and implementation outcomes and whether clinic (i.e., implementation climate) or clinician factors (i.e., treatment attitudes) were associated with effectiveness and implementation. Intent-to-treat analyses indicated WET was effective in reducing PTSD ( d = 0.54) and depression symptoms ( d = 0.39). Data indicated that 87.60% of clinicians reported using WET 6 months postconsultation. Clinic-wide reach was modest after training (14.53% of individuals with PTSD); however, WET-trained clinicians continued to offer WET to an average of 87.38% of their patients. Fidelity remained high after training, with essential session elements most often being offered "always" ( M = 6.65 on a scale from 1 to 7). More positive postconsultation clinician treatment attitudes predicted higher posttraining rates of having patients engaged in WET. Clinician treatment attitudes and implementation climate did not predict any other implementation or effectiveness outcomes examined. Results suggest that WET implementation is advancing in VHA, with good clinical outcomes. Data provide evidence that a facilitated learning collaborative can be used to support and scale EBPs. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
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- 2024
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33. Preliminary Efficacy of Positive Change(+Change): A Pilot Randomized Controlled Trial of an Integrated Alcohol and Sexual Assault Prevention Program Tailored by Gender and Sexual Orientation.
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Gilmore AK, Nielsen KE, Salamanca NK, Oesterle DW, Parekh A, Leone RM, Orchowski LM, Ramakrishnan V, Kaysen D, and Davis KC
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The current study presents preliminary efficacy findings of a pilot randomized controlled trial of Positive Change
© ( +Change© ). +Change© utilizes personalized normative feedback to target alcohol use, sexual assault (SA) victimization, SA perpetration, and bystander intervention tailored for heterosexual cisgender men, heterosexual cisgender women, and sexual and gender-minoritized (SGM) groups. Participants included 165 undergraduate students aged 18 to 25 years old from a large public university in the Southwestern U.S. who engaged in past month heavy episodic drinking. Participants (57 cisgender heterosexual men; 54 cisgender heterosexual women; and 54 SGM) were randomized to +Change© ( n = 83) or an assessment-only control ( n = 82) and completed surveys online at baseline and 3-month follow-up in a parallel design with a 1:1 ratio (NCT04089137). The current study presents the secondary outcomes of the pilot randomized controlled trial which include alcohol use, SA victimization, SA perpetration, and bystander intervention behavior. +Change© was associated with significantly less severe SA victimization and more bystander intervention behavior at 3-month follow-up relative to the control. There were no significant differences between conditions in alcohol use at 3-month follow-up, however, the magnitude of decreases in drinking in the +Change© condition in this pilot study were consistent with other personalized normative feedback interventions. The present study was unable to assess differences in SA perpetration due to low base rates. No adverse effects among those receiving the intervention were observed. Findings suggested that +Change© may be a feasible strategy to prevent SA, by reducing student SA victimization and increasing bystander intervention. A fully powered randomized clinical trial is needed to examine the effects of +Change© ., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interests with respect to the authorship and/or publication of this article.- Published
- 2024
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34. Parenthood and the physical and mental health of sexual and gender minority parents: A cross-sectional, observational analysis from The PRIDE Study.
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Tordoff DM, Lunn MR, Snow A, Monseur B, Flentje A, Lubensky ME, Dastur Z, Kaysen D, Leonard SA, and Obedin-Maliver J
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- Humans, Female, Male, Adult, Cross-Sectional Studies, Adolescent, Middle Aged, Depression epidemiology, Depression psychology, Young Adult, United States epidemiology, Longitudinal Studies, Anxiety epidemiology, Health Status, Parents psychology, Mental Health, Sexual and Gender Minorities psychology, Sexual and Gender Minorities statistics & numerical data
- Abstract
Purpose: To compare the physical and mental health of sexual and gender minority (SGM) parents to SGM non-parents., Methods: A cross-sectional analysis using 2018-2020 data from The PRIDE Study, a national longitudinal cohort of SGM adults. We used Poisson regression adjusted for age, gender, relationship status, race/ethnicity, household income, and education to assess the association between parental status and each outcome., Results: Among 9625 SGM participants, 1460 (15 %) were parents. Older participants were more likely to be parents: 2% of participants aged 18-30, 18% aged 30-39, and 38% aged 40+ were parents. In adjusted analyses, parenthood was associated with greater depression, anxiety, and post-traumatic stress symptoms as well as ever cigarette smoking. Among individuals assigned female sex at birth, parents were twice as likely to have been diagnosed with pelvic inflammatory disease compared to non-parents. There was no association between parenthood status and alcohol use, substance use, diabetes, HIV, hypertension, or autism., Conclusions: In this national cohort of SGM adults, parenthood was associated with differences in physical and mental health measures. Understanding how parenthood influences the health and well-being of the estimated 3 million SGM parents in the US will help our health systems support diverse families., Competing Interests: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Mitchell R. Lunn reports financial support was provided by Patient-Centered Outcomes Research Institute. Dr. Obedin-Maliver was partially supported by the National Institute of Diabetes, Digestive, and Kidney Disorders [grant number K12DK111028]. Dr. Flentje was partially supported by the National Institute on Drug Abuse [grant number K23DA039800]. Dr. Obedin-Maliver received consultation fees from Ibis Reproductive Health, Hims Inc., Folx Health Inc., and Sage Therapeutics on topics unrelated to this work. Dr. Lunn received consultation fees from Hims Inc., Folx Health Inc., and Otsuka Pharmaceutical Development and Commercialization, Inc. on topics unrelated to this work. All other authors have no conflicts of interest to report., (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Published
- 2024
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35. A month in review: longitudinal dynamics between daily PTSD symptom networks, affect, and drinking behaviors in female college students.
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Balters S, Schlichting M, Walton TO, Kochenderfer MJ, and Kaysen D
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Introduction: Sexual victimization (SV) is common among college women, with approximately half of those who have experienced SV meeting criteria for posttraumatic stress disorder (PTSD) within a year. Both SV and PTSD are associated with alcohol misuse among college women, often explained by the self-medication hypothesis. Existing literature focuses on overall PTSD severity rather than potential day-to-day fluctuations in specific symptoms, which might play a crucial role in understanding alcohol misuse risk. Studies also examine only same-day or next-day associations between PTSD and drinking, neglecting the potential for longer-term changes., Methods: This study explores the short-term longitudinal stability and time-lagged predictive dynamics of PTSD symptoms, affect, and drinking behavior among 174 female college heavy episodic drinkers over four weeks. Participants were categorized into three groups: those with a history of SV and PTSD (n = 77), women with SV but without PTSD ( n = 59), and women without prior trauma history ( n = 38) to be able to examine differences by trauma exposure, and PTSD. We compared the longitudinal stability of PTSD symptom networks, affect (arousal, positive affect, and negative affect), and drinking behavior across groups. Support vector regression determined which PTSD symptom networks and affect best predict drinking behavior at specific time lags within a 0-7 day range., Results: The PTSD group showed higher longitudinal stability for PTSD symptom networks (adjusted p s <.049) and arousal (adjusted p s <.048), but lower stability for negative affect (adjusted p =.013) and drinking behavior, including alcohol cravings (adjusted p =.019) and consumption (adjusted p s =.012), compared to the comparison groups. This suggests individuals with PTSD have more stable symptoms and arousal levels but greater fluctuations in negative affect and alcohol-related behaviors. Secondary analysis revealed PTSD symptom networks optimally predicted alcohol cravings with a three-day time lag (r=.88, p <.001) and consumption with a four-day time lag (r=.82, p <.001)., Discussion: These findings challenge assumptions regarding immediate effects of PTSD and affect on drinking behavior and underscore the need for therapeutic approaches that consider longer-range effects. Future research should expand on these findings by incorporating longer-range assessments and exploring a broader range of symptom interactions., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Balters, Schlichting, Walton, Kochenderfer and Kaysen.)
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- 2024
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36. Alcohol use disorder as a moderator of the relationship between posttraumatic stress disorder and suicidality among military personnel.
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Walton TO, Graupensperger S, Walker DD, and Kaysen D
- Abstract
Background: Alcohol use disorder (AUD), posttraumatic stress disorder (PTSD), and suicide are substantial public health concerns among military service members, yet the nature of their relationships is not well understood. Here, we tested the hypothesis that AUD moderates the relationship between PTSD symptom severity and suicidal ideation., Methods: This secondary analysis uses data collected at baseline for a randomized clinical trial. The sample consists of 160 active-duty service members from three service branches (Army, Air Force, and Navy). All participants met diagnostic criteria for PTSD and were not engaged in evidence-based PTSD treatment at the time of enrollment. Zero-inflated Poisson generalized linear regression models were used to test the associations of PTSD and AUD symptom severity with the presence and severity of suicidal ideation., Results: Findings suggest that AUD symptom severity moderates (i.e., amplifies) the relationship between PTSD symptoms and severity of suicidal ideation among military personnel with untreated PTSD. Among service members with mild or absent AUD, we found no significant association between PTSD symptoms and the severity of suicidal ideation. However, when AUD severity was average (i.e., sample mean) or high (mean + 1SD), PTSD symptoms were significantly positively associated with the severity of suicidal ideation., Conclusions: This study highlights the importance of assessing AUD and PTSD as a part of suicide risk evaluations of veterans. The results also provide strong support for the maintenance and further development in the military health system of treatment programs that simultaneously address AUD and PTSD comorbidity., (© 2024 Research Society on Alcohol.)
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- 2024
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37. Contexts of social alcohol and cannabis use among sexual minority cisgender women and gender diverse individuals: Event-level differences in alcohol and cannabis use patterns based on the sexual orientations and gender identities of substance use companions.
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Dyar C, Dworkin ER, and Kaysen D
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- Female, Humans, Male, Gender Identity, Sexual Behavior, Adolescent, Young Adult, Adult, Cannabis, Sexual and Gender Minorities, Substance-Related Disorders epidemiology
- Abstract
Purpose: Sexual minority women and gender diverse individuals assigned female at birth (SMWGD) are at elevated risk for alcohol and cannabis use disorders. It has been posited that characteristics of SMWGD's substance use companions (i.e., sexual orientation, gender identity) may influence their own use, but few studies have tested this. The current study aimed to examine whether quantity and consequences of substance use varied based on sexual orientations and gender identities (SOGI) of SMWGD's substance use companions., Methods: We utilized a 30-day ecological momentary assessment study of substance use among a sample of 429 SMWGD. We examined event-level associations between characteristics of substance use companions and quantity and consequences of substance use., Results: When SMWGD used alcohol/cannabis with most SOGI groups, they engaged in heavier drinking and cannabis use. Drinking with heterosexual men and SMW was associated with more drinking consequences. Drinking in settings with more SOGI groups and with both LGBTQ+ and heterosexual individuals was associated with heavier drinking and more consequences. Many contextual aspects of cannabis use settings predicted an increased likelihood of alcohol and cannabis co-use, while few contextual aspects of drinking settings were associated with co-use., Conclusion: Results suggest that SMWGD engage in heavier substance use when individuals from a range of SOGI groups are present, highlighting that heavy alcohol and cannabis use is not limited to use with SMW and nonbinary individuals. Drinking in setting with more SOGI groups present (e.g., parties and bars) appears to be associated with particularly heavy drinking and consequences., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Ltd. All rights reserved.)
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- 2024
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38. Doomscrolling: Prospective associations between daily COVID news exposure, internalizing symptoms, and substance use among sexual and gender minority individuals assigned female at birth.
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Dyar C, Crosby S, Newcomb ME, Mustanski B, and Kaysen D
- Abstract
Cross-sectional studies have demonstrated associations between COVID news exposure, anxiety, and depression. However, longitudinal research examining the directionality of these associations is extremely limited. Further, most studies have focused on the general population and neglected sexual and gender minority individuals (SGM), a population disproportionately impacted by the pandemic. To address these limitations, the current study utilized data from a 30-day diary study of SGM assigned female at birth ( N = 429). We examined concurrent and prospective associations between COVID news exposure, depressed and anxious affect, COVID distress, substance use, and motives for use. Further, we examined associations between cumulative COVID news exposure across the diary period and prospective changes in anxiety, depression, and COVID distress. When participants were exposed to more COVID news, they experienced more depressed and anxious affect, more COVID distress, less positive affect, and were more likely to use alcohol and cannabis to cope. Further, when participants were exposed to more COVID news, they experienced subsequent increases in depressed affect, decreases in positive affect, and increases in the likelihood of using cannabis to cope. Findings also provided evidence of bi-directional prospective associations between COVID news exposure and COVID distress and of a cumulative impact of COVID news exposure on anxiety, depression, and COVID distress. Findings suggest that individuals should balance the need to remain informed about the pandemic and their own mental health when considering how much COVID news to consume.
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- 2024
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39. Minimal important difference metrics and test-retest reliability of the PTSD Checklist for DSM-5 with a primary care sample.
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Blanchard BE, Johnson M, Campbell SB, Reed DE 2nd, Chen S, Heagerty PJ, Marx BP, Kaysen D, and Fortney JC
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- Adult, Humans, Female, United States, Checklist, Reproducibility of Results, Psychometrics, Primary Health Care, Stress Disorders, Post-Traumatic diagnosis
- Abstract
The PTSD Checklist for DSM-5 (PCL-5) is a measure of posttraumatic stress disorder (PTSD) symptom severity that is widely used for clinical and research purposes. Although previous work has examined metrics of minimal important difference (MID) of the PCL-5 in veteran samples, no work has identified PCL-5 MID metrics among adults in primary care in the United States. In this secondary analysis, data were evaluated from primary care patients (N = 971) who screened positive for PTSD and participated in a large clinical trial in federally qualified health centers in three U.S. states. Participants primarily self-identified as women (70.2%) and White (70.3%). We calculated test-retest reliability using clinic registry data and multiple distribution- and anchor-based metrics of MID using baseline and follow-up survey data. Test-retest reliability (Pearson's r, Spearman's ρ, intraclass correlation coefficient) ranged from adequate to excellent (.79-.94), with the shortest time lag demonstrating the highest reliability estimate. The MID for the PCL-5 was estimated using multiple approaches. Distribution-based approaches indicated an MID range of 8.5-12.5, and anchor-based approaches indicated an MID range of 9.8-11.7. Taken together, the MID metrics indicate that PCL-5 change scores of 9-12 likely reflect real change in PTSD symptoms and indicate at least an MID for patients, whereas PCL-5 change scores of 5 or less likely are not reliable. These findings can help inform clinicians using the PCL-5 in similar populations to track patient responses to treatment and help researchers interpret PCL-5 score changes in clinical trials., (© 2023 International Society for Traumatic Stress Studies.)
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- 2023
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40. An eHealth Prevention Program for Substance Use, Sexual Assault, and Sexual Risk Behaviors for Adolescents in Primary Care: Pilot Feasibility Randomized Controlled Trial of Teen Well Check.
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Gilmore AK, Fortson K, Mullican KN, García-Ramírez G, Hutchins A, Bartlett AM, Gooding HC, Wallis E, Levy S, Ruggiero KJ, Kaysen D, Danielson CK, Platner R, Hartman A, and Self-Brown S
- Abstract
Background: Substance use, sexual assault, and sexual risk behaviors are common among adolescents and are interrelated. Nearly 1 in 5 adolescents use substances before sexual encounters, placing these young people at risk for both sexual assault and sexual risk behaviors. Primary care visits present a unique opportunity to address multiple health risk behaviors., Objective: Teen Well Check is a web-based integrated prevention program for substance use, sexual assault, and sexual risk behaviors with demonstrated usability and acceptability among patients and providers. The aim of this study was to conduct a pilot randomized controlled trial to assess feasibility., Methods: Adolescents (n=123) aged 14 to 18 years from diverse backgrounds were recruited from primarily Medicaid-serving pediatric primary care clinics. Participants completed a baseline survey; were randomized to receive Teen Well Check or an assessment-only control; and completed 1-, 3-, and 6-month follow-up surveys. Feasibility was assessed in terms of recruitment and retention rates. Preliminary changes from baseline to follow-up periods were examined separately in the Teen Well Check and control conditions., Results: We recruited 123 participants (Teen Well Check: n=61, 49.6%; control: n=62, 50.4%). Of the 61 participants assigned to the Teen Well Check condition, 55 (90%) completed the full program and viewed all intervention content. Of the 123 participants, 105 (85.4%) were retained across at least 1 follow-up period, and there was no difference in follow-up rates between the conditions (χ
2 1 =0.6; P=.43). The completion of Teen Well Check took an average of 6.2 (SD 5.8) minutes. Preliminary analyses revealed that there were significant reductions in perceived peer norms (descriptive norms) for substance use before sex across follow-ups among participants in the Teen Well Check condition (P=.001 from baseline to 6 months), whereas there were significant increases among participants in the control condition (P=.003 from baseline to 6 months). In addition, there were nonsignificant reductions in substance misuse risk from baseline to the 6-month follow-up among participants in the Teen Well Check condition (P=.16)., Conclusions: These findings support the feasibility of Teen Well Check delivery within pediatric primary care clinics. A randomized clinical trial is needed to assess efficacy., Trial Registration: ClinicalTrials.gov NCT3489434; https://www.clinicaltrials.gov/study/NCT03489434., (©Amanda K Gilmore, Kennicia Fortson, K Nicole Mullican, Grisel García-Ramírez, Anna Hutchins, Alyssa M Bartlett, Holly C Gooding, Elizabeth Wallis, Sharon Levy, Kenneth J Ruggiero, Debra Kaysen, Carla Kmett Danielson, Robert Platner, April Hartman, Shannon Self-Brown. Originally published in JMIR Formative Research (https://formative.jmir.org), 02.11.2023.)- Published
- 2023
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41. Associations among sexual assault, posttraumatic stress, drinking to cope with anxiety, and alcohol use based on gender identity and sexual orientation.
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Kilimnik CD, García-Ramírez G, Salamanca NK, Mazzone GM, Mullican KN, Davis KC, Orchowski LM, Leone RM, Kaysen D, and Gilmore AK
- Abstract
Background: Sexual assault (SA) is experienced by a substantial proportion of emerging adult college students and is associated with elevated rates of posttraumatic stress disorder (PTSD) and alcohol use. This study examines the mediating role of posttraumatic stress symptoms (PTSS) in the associations among SA severity, drinking to cope with anxiety, and average weekly drinks while considering the moderating roles of gender identity and sexual orientation., Methods: A total of 2160 college students who were diverse in gender (cisgender women, 64.4%; cisgender men, 30.6%, and transgender and gender diverse [TGD] individuals = 4.9%) and sexual orientation (heterosexual = 68.0%, LGBQ+ = 32.0%) completed measures of SA severity, PTSS, drinking to cope with anxiety motives, and average weekly drinks., Results: The mediation model for the full sample indicated significant indirect effects of SA severity on drinking to cope with anxiety through PTSS, but not on average weekly drinks. Moderation analyses revealed differential relationships between the variables based on both gender identity and sexual orientation. For instance, the association between SA severity and PTSS was stronger for cisgender women and TGD individuals than cisgender men, and for LGBQ+ individuals than heterosexual individuals. While the association between PTSS and average weekly drinks was only significant for cisgender men, the association between PTSS and drinking to cope with anxiety was significant for both cisgender men and women but not TGD individuals. Furthermore, the association between SA severity and drinking to cope with anxiety was stronger for cisgender women than cisgender men., Conclusions: Findings from this study demonstrate sexual orientation and gender identity differences and similarities in the associations of SA severity, PTSS, drinking to cope with anxiety, and alcohol use. Results are discussed in relation to the self-medication hypothesis and tailoring interventions for diverse groups., (© 2023 Research Society on Alcohol.)
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- 2023
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42. Trends in Cannabis and Alcohol Use by Sexual Identity in the 2015-2019 National Survey on Drug Use and Health.
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Dyar C, Morgan E, and Kaysen D
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- Male, Humans, Female, Alcohol Drinking, Bisexuality, Cannabis, Substance-Related Disorders epidemiology, Sexual and Gender Minorities, Alcoholism epidemiology
- Abstract
Objective: Sexual minority individuals are at substantially elevated risk for both cannabis use disorder (CUD) and alcohol use disorder (AUD). Although recent increases in the legalization of cannabis have been linked to increases in cannabis use among the general population, few studies have examined if changes in cannabis use and CUD vary by sexual identity. The purpose of the current study was to examine sexual identity differences in trends for CUD and compare them to trends for AUD., Method: We used data from 2015-2019 National Survey on Drug Use and Health to examine annual prevalence and year-specific disparities in cannabis use, CUD, heavy episodic drinking, and AUD. We also examined sex-specific sexual identity differences in linear trends for these substance use outcomes over this 5-year period., Results: All groups except lesbian females experienced significant increases in cannabis use rates from 2015 to 2019. Heterosexual males, heterosexual females, and bisexual females also experienced significant increases in CUD rates. In contrast, no group exhibited significant increases in heavy episodic drinking or AUD rates. Bisexual women exhibited some of the largest year-specific disparities in cannabis use and CUD as well as the largest growth in disparities across time., Conclusions: The few changes in heavy episodic drinking and AUD alongside numerous changes in cannabis use and CUD suggest that changes in cannabis use may be attributable to legalization of cannabis use in many states during this period. Given profound disparities and increasing rates of CUD affecting bisexual females, further research is needed to identify factors that may explain their disproportionate burden.
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- 2023
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43. Event-level positive and negative reinforcement risk factors for alcohol use: Moderation by individual-level alcohol consequences and post-traumatic stress disorder symptom severity.
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Dyar C and Kaysen D
- Abstract
Background: The multistage model of drug addiction posits that risk processes contributing to alcohol use change as individuals develop alcohol use disorders. However, few studies have tested this theory outside of the lab or at the event level. We assessed whether event-level associations between positive reinforcement (e.g., positive affect, sociability expectancies) and negative reinforcement risk factors (e.g., negative affect, tension reduction expectancies) and same-/next-day alcohol consumption varied as a function of an individual's level of alcohol consequences. Given elevated alcohol use consequences among individuals with post-traumatic stress disorder (PTSD) and disruptions in reward processing that affect this population, we also tested whether these processes differed based on the presence and severity of PTSD., Methods: We used data from a 30-day ecological momentary assessment study with 174 undergraduate women who regularly engaged in heavy episodic drinking. A majority (78%) of the sample had experienced sexual assault and 44% had current PTSD. Analyses used Bayesian multilevel structural equation modeling with diffuse (non-informative) priors. We used markov chain monte carlo (MCMC) algorithms to generate a series of 10,000 random draws from the multivariate posterior distribution of our sample for each model., Results: Results partially supported the multistage model. Event-level negative reinforcement risk factors only predicted more alcohol consumption among individuals who experienced more alcohol consequences. Findings for positive reinforcement risk factors were partially consistent with hypotheses. Overall, findings appear to operate similarly across PTSD symptom severity., Conclusions: Results suggest that interventions for heavy episodic drinking could benefit from attending to an individual's level of alcohol consequences. For example, preventive interventions for individuals who tend to experience few consequences may benefit more from addressing positive reinforcement risk factors, while treatment interventions for those who experience more consequences may benefit from attending to both positive and negative reinforcement., (© 2023 The Authors. Alcohol: Clinical and Experimental Research published by Wiley Periodicals LLC on behalf of Research Society on Alcohol.)
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- 2023
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44. Improving voluntary engagement for posttraumatic stress disorder treatment among active-duty service members using motivational enhancement therapy.
- Author
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Walker DD, Walton TO, Jaffe AE, Graupensperger S, Rhew IC, and Kaysen D
- Abstract
Objective: Posttraumatic stress disorder (PTSD) prevalence in the military is high and effective treatments are underutilized. Motivational enhancement therapy (MET) "check-ups" are brief interventions to elicit treatment uptake for those who are nontreatment seeking. The aim of the current study was to test the efficacy of a novel MET intervention designed to promote treatment engagement among active-duty U.S. military personnel with untreated PTSD., Method: One hundred and sixty-one active-duty service members who met the criteria for PTSD were randomized to MET or treatment as usual (TAU, treatment resource and referral). MET participants ( n = 82) received up to three 30-90 min telephone sessions. TAU participants ( n = 79) were mailed PTSD resources and referrals. Follow-up assessments were conducted 6-week, 3- and 6-month postbaseline., Results: Mixed effect model results indicated treatment uptake significantly increased over time but there were no significant differences between conditions or interactions. PTSD symptom severity significantly decreased for both conditions. There was also a significant three-way interaction with baseline readiness-to-change confidence. Those low in baseline readiness-to-change saw more favorable effects of MET (relative to TAU) at 6-month follow-up., Conclusions: Results suggest both MET and high-quality referral options have promise as a means of increasing evidence-based treatment uptake and decreasing PTSD for service members with PTSD. MET may be particularly useful for individuals with low confidence in their ability to address PTSD. Given the individual and societal costs of PTSD, there is a need for interventions facilitating treatment uptake. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
- Published
- 2023
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45. Recruiting Sexual and Gender Minority Veterans for Health Disparities Research: Recruitment Protocol of a Web-Based Prospective Cohort Study.
- Author
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Fan CA, Upham M, Beaver K, Dashtestani K, Skiby MM, Pentel KZ, Rhew IC, Kauth MR, Shipherd JC, Kaysen D, Simpson T, and Lehavot K
- Abstract
Background: The Health for Every Veteran Study is the first Veterans Health Administration-funded, nationwide study on lesbian, gay, bisexual, transgender, queer, and other sexual and gender minority (LGBTQ+) veterans' health that relies exclusively on primary recruitment methods. This study aimed to recruit 1600 veterans with diverse sexual and gender identities to study the mental health and health risk behaviors of this population. A growing body of literature highlights the health inequities faced by LGBTQ+ veterans when compared with their heterosexual or cisgender peer groups. However, there is little to no guidance in the health disparities literature describing the recruitment of LGBTQ+ veterans., Objective: This paper provides an overview of the recruitment methodology of Health for Every Veteran Study. We describe the demographics of the enrolled cohort, challenges faced during recruitment, and considerations for recruiting LGBTQ+ veterans for health research., Methods: Recruitment for this study was conducted for 15 months, from September 2019 to December 2020, with the goal of enrolling 1600 veterans evenly split among 8 sexual orientation and gender identity subgroups: cisgender heterosexual women, cisgender lesbian women, cisgender bisexual women, cisgender heterosexual men, cisgender gay men, cisgender bisexual men, transgender women, and transgender men. Three primary recruitment methods were used: social media advertising predominantly through Facebook ads, outreach to community organizations serving veterans and LGBTQ+ individuals across the United States, and contracting with a research recruitment company, Trialfacts., Results: Of the 3535 participants screened, 1819 participants met the eligibility criteria, and 1062 completed the baseline survey to enroll. At baseline, 25.24% (268/1062) were recruited from Facebook ads, 40.49% (430/1062) from community outreach, and 34.27% (364/1062) from Trialfacts. Most subgroups neared the target enrollment goals, except for cisgender bisexual men, women, and transgender men. An exploratory group of nonbinary and genderqueer veterans and veterans with diverse gender identities was included in the study., Conclusions: All recruitment methods contributed to significant portions of the enrolled cohort, suggesting that a multipronged approach was a critical and successful strategy in our study of LGBTQ+ veterans. We discuss the strengths and challenges of all recruitment methods, including factors impacting recruitment such as the COVID-19 pandemic, negative comments on Facebook ads, congressional budget delays, and high-volume surges of heterosexual participants from community outreach. In addition, our subgroup stratification offers important disaggregated insights into the recruitment of specific LGBTQ+ subgroups. Finally, the web-based methodology offers important perspectives not only for reaching veterans outside of the Veterans Health Administration but also for research studies taking place in the COVID-19-impacted world. Overall, this study outlines useful recruitment methodologies and lessons learned to inform future research that seeks to recruit marginalized communities., International Registered Report Identifier (irrid): DERR1-10.2196/43824., (©Carolyn A Fan, Michelle Upham, Kristine Beaver, Krista Dashtestani, Malachi M Skiby, Kimberly Z Pentel, Isaac C Rhew, Michael R Kauth, Jillian C Shipherd, Debra Kaysen, Tracy Simpson, Keren Lehavot. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 02.10.2023.)
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- 2023
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46. Sexual Assault, Posttraumatic Stress, Alcohol Use, and Suicidality Among Diverse College Students.
- Author
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Gilmore AK, López CM, Mullican KN, Davis KC, Leone RM, Orchowski LM, Kaysen D, and Moreland AD
- Subjects
- Humans, Female, Male, Young Adult, Suicidal Ideation, Gender Identity, Universities, Students, Suicide, Stress Disorders, Post-Traumatic epidemiology, Sex Offenses, Sexual and Gender Minorities
- Abstract
Suicide is the second leading cause of death among college-aged populations. This study examined the association of demographics (sexual orientation, gender identity, age, and race), sexual assault, posttraumatic stress symptoms (PTSS), and alcohol use with suicidality, current urge to self-harm, and current suicidal intent among a diverse sample of college students ( n = 2,160) from two universities. Over half of participants reported any suicidality (63.5%), 12% reported current urge to harm themselves, and 5% reported current suicidal intent. A linear regression indicated that participants who identified as a sexual minority, gender minority, consumed more drinks per week, and had more severe PTSS reported higher levels of suicidality. University also was associated with suicidality. A negative binomial regression demonstrated that participants who identified as a sexual minority and had more severe PTSS had more current urge to harm themselves. Further, a negative binomial regression demonstrated that first-generation college students, students with more severe sexual assault histories, and students with more severe PTSS had higher current suicidal intent. Findings suggest that risk factors may differ for college students' general suicidality, self-harm urges, and suicidal intent, suggesting that these may be separate constructs. More comprehensive models, incorporating multiple risk factors and multiple ways of assessing suicidality, are needed to better understand the range of college student suicidal behavior and risks.
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- 2023
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47. A systematic review of patient-reported outcome measures used in maternal postpartum anxiety.
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O'Carroll J, Ando K, Yun R, Panelli D, Nicklin A, Kennedy N, Carvalho B, Blake L, Coker J, Kaysen D, and Sultan P
- Subjects
- Humans, Anxiety diagnosis, Anxiety epidemiology, Anxiety etiology, Patient Reported Outcome Measures, Psychometrics, COVID-19
- Abstract
Objective: This study aimed to conduct a systematic review and to evaluate the psychometric measurement properties of instruments for postpartum anxiety using the Consensus-Based Standards for the Selection of Health Measurement Instruments guidelines to identify the best available patient-reported outcome measure., Data Sources: We searched 4 databases (CINAHL, Embase, PubMed, and Web of Science in July 2022) and included studies that evaluated at least 1 psychometric measurement property of a patient-reported outcome measurement instrument. The protocol was registered with the International Prospective Register for Systematic Reviews under identifier CRD42021260004 and followed the Consensus-Based Standards for the Selection of Health Measurement Instruments guidelines for systematic reviews., Study Eligibility: Studies eligible for inclusion were those that assessed the performance of a patient-reported outcome measure for screening for postpartum anxiety. We included studies in which the instruments were subjected to some form of psychometric property assessment in the postpartum maternal population, consisted of at least 2 questions, and were not subscales., Methods: This systematic review used the Consensus-Based Standards for the Selection of Health Measurement Instruments and the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines to identify the best patient-reported outcome measurement instrument for examining postpartum anxiety. A risk of bias assessment was performed, and a modified GRADE approach was used to assess the level of evidence with recommendations being made for the overall quality of each instrument., Results: A total of 28 studies evaluating 13 instruments in 10,570 patients were included. Content validity was sufficient in 9 with 5 instruments receiving a class A recommendation (recommended for use). The Postpartum Specific Anxiety Scale, Postpartum Specific Anxiety Scale Research Short Form, Postpartum Specific Anxiety Scale Research Short Form Covid, Postpartum Specific Anxiety Scale-Persian, and the State-Trait Anxiety Inventory demonstrated adequate content validity and sufficient internal consistency. Nine instruments received a recommendation of class B (further research required). No instrument received a class C recommendation (not recommended for use)., Conclusion: Five instruments received a class A recommendation, all with limitations, such as not being specific to the postpartum population, not assessing all domains, lacking generalizability, or evaluation of cross-cultural validity. There is currently no freely available instrument that assess all domains of postpartum anxiety. Future studies are needed to determine the optimum current instrument or to develop and validate a more specific measure for maternal postpartum anxiety., (Copyright © 2023 Elsevier Inc. All rights reserved.)
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- 2023
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48. mHealth Early Intervention to Reduce Posttraumatic Stress and Alcohol Use After Sexual Assault (THRIVE): Feasibility and Acceptability Results From a Pilot Trial.
- Author
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Dworkin ER, Schallert M, Lee CM, and Kaysen D
- Abstract
Background: Sexual assault is associated with increased risk for both posttraumatic stress (PTS) and alcohol misuse. Mobile health interventions have shown promise in addressing PTS and substance use in trauma survivors and might be a promising strategy in extending the reach of early interventions to individuals who have recently experienced trauma., Objective: This study assesses the feasibility and acceptability of THRIVE, a mobile health early intervention for recent survivors of sexual assault involving a cognitive behavioral app used daily over 21 days with weekly telephone coaching., Methods: Twenty adult female survivors of past-10-week sexual assault with elevated PTS and alcohol use were randomized to receive the THRIVE intervention as part of a pilot randomized controlled trial. We sought to understand feasibility by examining rates of completion of intervention activities and testing changes in participants' self-reported knowledge of key intervention concepts from baseline to after the intervention. We assessed acceptability by collecting self-report ratings of satisfaction with the intervention and app usability in a follow-up survey. The coach took notes during coaching calls to track call content and record participant feedback; these notes were qualitatively analyzed to elaborate on the aforementioned domains., Results: Feasibility was demonstrated by moderate rates of activity completion: all participants at least opened the app, 19 (95%) of the 20 participants completed at least 1 cognitive behavioral exercise, and 16 (80%) of the 20 participants attended all 4 coaching calls. Participants completed cognitive behavioral exercises on an average of 10.40 (SD 6.52) out of 21 days. The coaching call notes documented participant comments that app-generated reminders increased completion rates. Feasibility was also demonstrated by the finding that knowledge changes occurred from baseline to after the intervention; this indicated that THRIVE was successful in conveying key concepts. Acceptability was demonstrated by high participant ratings of THRIVE's usability; the ratings corresponded to a B+ usability grade. The coaching call notes documented that usability was increased by the coaching calls, the app exercises' clarity, and the app exercises' inclusion of suggestions; however, the coaching call notes also documented that some of the participants found aspects of the app exercises to be difficult or confusing. Acceptability was also demonstrated by participant ratings of satisfaction: most of the participants (15/16, 94%) rated the app as either moderately helpful or very helpful. The coaching call notes documented that the cognitive behavioral activity modules were seen as appealing and that the positive impact of the intervention contributed to participants' satisfaction., Conclusions: These findings suggest that THRIVE is feasible and acceptable to survivors of recent sexual assault and that further testing of THRIVE is warranted., Trial Registration: ClinicalTrials.gov NCT03703258; https://clinicaltrials.gov/ct2/show/NCT03703258., (©Emily R Dworkin, Macey Schallert, Christine M Lee, Debra Kaysen. Originally published in JMIR Formative Research (https://formative.jmir.org), 04.07.2023.)
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- 2023
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49. A Community Engaged Approach in Adapting Motivational Interviewing and Skills Training for Native Americans With Experiences of Substance Misuse.
- Author
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Walker D, Pearson C, Day A, Bedard-Gilligan M, Saluskin K, Huh D, and Kaysen D
- Subjects
- Aged, Humans, Indians, North American psychology, Cognitive Behavioral Therapy, Clinical Competence, American Indian or Alaska Native psychology, Motivational Interviewing, Substance-Related Disorders prevention & control, Substance-Related Disorders psychology, Substance-Related Disorders therapy, Culturally Competent Care
- Abstract
Objective: American Indian and Alaskan Natives (AIAN) are regenerating cultural knowledge and practices to adapt westernized evidence-based interventions to address health concerns such as substance use. This study describes the process of selecting, adapting, and implementing motivational interviewing plus cognitive behavior therapy (motivational interviewing + Skills Training; MIST) for use in a combined substance use intervention with a rural, Northwest tribal community., Methods: An established community and academic partnership worked together to make culturally mindful changes to MIST. The partnership incorporated community leaders/Elders (n = 7), providers (n = 9), and participants (n = 50) to implement an iterative process of adapting and implementing the adapted form of MIST., Results: Key adaptations included presenting concepts grounded in tribal values, providing examples from the community perspective, and incorporating cultural customs and traditions. Overall, the MIST adaptation was favorably received by participants, and the adaptation appeared feasible., Conclusions: Adapted MIST appeared to be an acceptable intervention for this Native American community. Future research should evaluate the interventions efficacy in reducing substance use among this and other Native American communities. Future clinical research should consider strategies outlined in this adaptation as a potential process for working with Native American communities to implement culturally appropriate interventions.
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- 2023
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50. Implicit trauma identity associations in treatment-seeking U.S. military personnel do not predict or change in response to cognitive processing therapy for PTSD.
- Author
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Lindgren KP, Jaffe AE, Kaysen D, Teachman BA, Young-McCaughan S, Peterson AL, Resick PA, and Wachen JS
- Subjects
- Humans, Female, Male, Cognition, Self Report, Military Personnel psychology, Stress Disorders, Post-Traumatic psychology, Cognitive Behavioral Therapy
- Abstract
Objective: This study evaluated implicit associations (i.e., associations in memory that are automatically activated and difficult to control consciously) related to trauma and one's self in the context of a clinical trial for active duty service members seeking treatment for posttraumatic stress disorder (PTSD). Previous studies with nontreatment-seeking community samples found that implicit trauma identity associations were associated with PTSD symptoms even after controlling for amount of trauma exposure and self-reported negative cognitions about the self. This study extended prior work by evaluating whether trauma-related implicit associations were associated with PTSD and depressive symptoms in a clinical sample seeking treatment for PTSD, predicted PTSD treatment response, or changed over the course of treatment., Method: This secondary analysis examined implicit trauma identity associations using data from a clinical trial evaluating a variable-length adaptation of cognitive processing therapy for military personnel. Participants were 127 active duty U.S. military personnel (13.4% women) seeking PTSD treatment. Implicit trauma identity associations were evaluated at baseline and posttreatment. Study hypotheses and data analysis plan were preregistered., Results: Contrary to predictions, baseline implicit trauma identity associations were not significantly associated with baseline PTSD or depressive symptoms and did not predict treatment response. Implicit trauma identity associations did not change significantly in response to treatment., Conclusions: More tailoring of implicit trauma measures for military personnel and/or treatment-seeking patients may be needed. The measure may lack sensitivity to change in response to treatment and have reduced utility in treatment-seeking samples with high symptom burden and less variability in symptoms. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
- Published
- 2023
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