1. Clinical impact of red blood cell transfusion on adverse clinical events in acute heart failure patients with anemia
- Author
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Takeaki Matsuda, Hiroshi Hasegawa, Tomoya Suda, Shigeki Shibata, Satoshi Higuchi, Kazukuni Hirabuki, Kazuna Honda, and Noritaka Hata
- Subjects
medicine.medical_specialty ,business.industry ,Clinical events ,Anemia ,Red Blood Cell Transfusion ,030204 cardiovascular system & hematology ,medicine.disease ,University hospital ,Comorbidity ,03 medical and health sciences ,Red blood cell ,0302 clinical medicine ,medicine.anatomical_structure ,Heart failure ,Internal medicine ,medicine ,030212 general & internal medicine ,Hemoglobin ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background Anemia has been recognized as an important comorbidity in patients with acute heart failure (AHF) and is associated with adverse clinical events. However, the clinical impact of red blood cell (RBC) transfusion in such patients is unclear. Method This study was a retrospective single-center registry including AHF patients admitted to Kyorin University Hospital between 2007 and 2014. Anemia was defined as a hemoglobin level 20 g/L were excluded. AHF readmission at 3 months and in-hospital and 2-year all-cause mortality were evaluated. Results Of 501 AHF patients, 38 were excluded owing to major bleeding; finally, 463 (age, 77 ± 11 years; males, 58%) were evaluated. RBC transfusion during hospitalization was performed in 112 patients (24%). Hemoglobin level on admission was 105 ± 16 g/L (transfusion, 89 ± 17 g/L; no transfusion, 110 ± 12 g/L; p Conclusions RBC transfusion was not associated with AHF readmission or all-cause mortality.
- Published
- 2021
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