1. Impact of red blood cell distribution width and mean platelet volume in patients with ST-segment elevation myocardial infarction
- Author
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Mutsuo Horii, Kiyoshi Hibi, Mai Okazaki, Megumi Tayama, Kazuo Kimura, Yasushi Matsuzawa, Nobuhiko Maejima, Toshiaki Ebina, Noriaki Iwahashi, Kozo Okada, Shiori Tochihara, Kouichi Tamura, Haruka Hirose, Yukiko Takanami, Kazuyo Koike, Masami Kosuge, and Yuko Tsuto
- Subjects
Male ,medicine.medical_specialty ,Erythrocytes ,medicine.medical_treatment ,Percutaneous Coronary Intervention ,Internal medicine ,medicine ,Humans ,ST segment ,Myocardial infarction ,Mean platelet volume ,Adverse effect ,Aged ,Retrospective Studies ,business.industry ,Percutaneous coronary intervention ,Red blood cell distribution width ,Prognosis ,medicine.disease ,Cardiac surgery ,Conventional PCI ,Cardiology ,ST Elevation Myocardial Infarction ,Female ,Cardiology and Cardiovascular Medicine ,business ,Mean Platelet Volume - Abstract
The complete blood cell count is one of the most frequently ordered laboratory tests, and many parameters, including red blood cell distribution width (RDW) and mean platelet volume (MPV), are available. The purpose of this study was to investigate the usefulness of the combination of RDW and MPV in patients with ST-segment elevation myocardial infarction (STEMI). Patients with STEMI who underwent primary percutaneous coronary intervention were retrospectively enrolled (n = 229). The association between RDW as well as MPV and cardiovascular events was investigated. The median age was 67 years, and males made up 85% of the sample. Median RDW was 13.6%, and median MPV was 8.2 fL. During a median follow-up period of 528 days (IQR 331.5-920.5), 41 patients died or experienced major adverse cardiac and cerebrovascular events (MACCEs). Patients with RDW ≧ 13.7% had more deaths or MACCEs with marginal significance (p = 0.0799). Patients with MPV ≧ 8.3 fL had significantly more deaths or MACCEs (p = 0.0283). Patients with RDW ≧ 13.7% and MPV ≧ 8.3 fL had significantly more deaths or MACCEs (p = 0.0185). MPV was significantly associated with death or adverse events in patients with STEMI who were treated with primary PCI. RDW had only a weak association with death or adverse events. The results of the combination of MPV and RDW were similar to those of MPV.
- Published
- 2021
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