284 results on '"Ke, Ailong"'
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2. Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications
3. Multiple adaptations underly co-option of a CRISPR surveillance complex for RNA-guided DNA transposition
4. Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools
5. Cas11 enables genome engineering in human cells with compact CRISPR-Cas3 systems
6. Mechanism for Cas4-assisted directional spacer acquisition in CRISPR–Cas
7. Reconstitution and biochemical characterization of the RNA-guided helicase-nuclease protein Cas3 from type I-A CRISPR–Cas system
8. Real-time observation of CRISPR spacer acquisition by Cas1–Cas2 integrase
9. Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas
10. Using tRNA Scaffold to Assist RNA Crystallization
11. Structure basis for RNA-guided DNA degradation by Cascade and Cas3
12. Assembly and Translocation of a CRISPR-Cas Primed Acquisition Complex
13. Structural basis for tRNA decoding and aminoacylation sensing by T-box riboregulators
14. The Crystal Structure of the Signal Recognition Particle in Complex with Its Receptor
15. Functional characterization and crystal structure of thermostable amylase from Thermotoga petrophila, reveals high thermostability and an unusual form of dimerization
16. Massively Parallel Biophysical Analysis of CRISPR-Cas Complexes on Next Generation Sequencing Chips
17. Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System
18. A fast and efficient procedure to produce scFvs specific for large macromolecular complexes
19. Building the Class 2 CRISPR-Cas Arsenal
20. Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications
21. Reconstitution and biochemical characterization of ribonucleoprotein complexes in Type I-E CRISPR–Cas systems
22. Sortase-mediated fluorescent labeling of CRISPR complexes
23. Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch
24. Mn2+-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches
25. How type II CRISPRCas establish immunity through Cas1Cas2-mediated spacer integration
26. Common themes and differences in SAM recognition among SAM riboswitches
27. Identification of a conserved branched RNA structure that functions as a factor-independent terminator
28. Craspase is a CRISPR RNA-guided, RNA-activated protease
29. Structural Determinants for Geometry and Information Decoding of tRNA by T Box Leader RNA
30. T box RNA decodes both the information content and geometry of tRNA to affect gene expression
31. Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli
32. How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration
33. Double-stranded Endonuclease Activity in Bacillus halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein
34. Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System
35. Elastic Coupling Between RNA Degradation and Unwinding by an Exoribonuclease
36. Engineering Antibody Fitness and Function Using Membrane-Anchored Display of Correctly Folded Proteins
37. Structural basis for RNA-guided DNA cleavage by IscB-ωRNA and mechanistic comparison with Cas9
38. Structure and assembly of the essential RNA ring component of a viral DNA packaging motor
39. Chapter Fourteen - Reconstitution and biochemical characterization of the RNA-guided helicase-nuclease protein Cas3 from type I-A CRISPR–Cas system
40. Crystal Structure of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Csn2 Protein Revealed Ca2+-dependent Double-stranded DNA Binding Activity
41. Variable Sequences outside the Sam-Binding Core Critically Influence the Conformational Dynamics of the SAM-III/SMK Box Riboswitch
42. Architecture of the Yeast Rrp44-Exosome Complex Suggests Routes of RNA Recruitment for 3' End Processing
43. tRNA Fusion to Streamline RNA Structure Determination: Case Studies in Probing Aminoacyl-tRNA Sensing Mechanisms by the T-Box Riboswitch
44. SAM Recognition and Conformational Switching Mechanism in the Bacillus subtilis yitJ S Box/SAM-I Riboswitch
45. Introducing Large Genomic Deletions in Human Pluripotent Stem Cells Using CRISPR‐Cas3
46. Structural basis of target-site selection in RNA-guided DNA transposition systems
47. Structural basis for target site selection in RNA-guided DNA transposition systems
48. Characterizing Metal-Dependent Nucleases of CRISPR-Cas Prokaryotic Adaptive Immunity Systems
49. Structures of Large RNAs and RNA–Protein Complexes
50. Structural basis for target site selection in RNA-guided DNA transposition systems
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