523 results on '"Kean, Leslie S"'
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2. Abatacept for acute graft-versus-host disease prophylaxis after unrelated donor hematopoietic cell transplantation
3. Abatacept for the prevention of graft versus host disease in pediatric patients receiving 7/8 HLA-mismatched unrelated transplant for hematologic malignancies: a real-world analysis
4. B-cell–directed CAR T-cell therapy activates CD8+ cytotoxic CARneg bystander T cells in patients and nonhuman primates
5. Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate–conditioned Fanconi anemia mice
6. Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium 2021: Looking Forward as the Network Celebrates its 20th Year
7. Abatacept for graft versus host disease prophylaxis in patients 60 years and older receiving mismatched unrelated donor transplantation for hematologic malignancies
8. Major breakthroughs in hematopoietic stem cell transplantation and future challenges in clinical implementation
9. The Adverse Event Landscape of Stem Cell Transplant: Evidence for AGVHD Driving Early Transplant Associated Toxicities
10. Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events
11. Real-world experience with low-dose IL-2 for children and young adults with refractory chronic graft-versus-host disease
12. Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity
13. Alemtuzumab and CXCL9 levels predict likelihood of sustained engraftment after reduced-intensity conditioning HCT
14. Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation
15. Engineering T cells to suppress acute GVHD and leukemia relapse after allogeneic hematopoietic stem cell transplantation
16. Retinoic acid signaling acts as a rheostat to balance Treg function
17. Organ-specific microenvironments drive divergent T cell evolution in acute graft-versus-host disease.
18. BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes
19. Standardizing Definitions of Hematopoietic Recovery, Graft Rejection, Graft Failure, Poor Graft Function, and Donor Chimerism in Allogeneic Hematopoietic Cell Transplantation: A Report on Behalf of the American Society for Transplantation and Cellular Therapy
20. Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion
21. Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses
22. Human OX40L–CAR-Tregs target activated antigen-presenting cells and control T cell alloreactivity.
23. Robust expansion of HIV CAR T cells following antigen boosting in ART-suppressed nonhuman primates
24. Risk factors for transplant-associated thrombotic microangiopathy and mortality in a pediatric cohort
25. SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
26. IL-2 enhances ex vivo–expanded regulatory T-cell persistence after adoptive transfer
27. Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality
28. Busulfan Combined with Immunosuppression Allows Efficient Engraftment of Gene-Modified Cells in a Rhesus Macaque Model
29. Reshaping of Local Alloimmunity By Organ-Specific Microenvironments during Acute Gvhd.
30. Enhanced Proliferation and Effector Function in PTPN2 Knockout CAR-T Cells Associated with Toxicities in a Non-Human Primate Model of CD20 CAR-T Cell Therapy
31. Defining success with cellular therapeutics: the current landscape for clinical end point and toxicity analysis
32. Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice
33. Reprint of: Building a Safer and Faster CAR: Seatbelts, Airbags, and CRISPR
34. Building a Safer and Faster CAR: Seatbelts, Airbags, and CRISPR
35. Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade
36. B cell directed CAR-T cell therapy results in activation of CD8+ cytotoxic CAR-negative bystander T cells in both non-human primates and patients
37. Isolation of a Highly Purified HSC-enriched CD34+CD90+CD45RA− Cell Subset for Allogeneic Transplantation in the Nonhuman Primate Large-animal Model
38. CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates
39. Abatacept for The Prevention of GVHD in Patients Receiving Mismatched Unrelated Transplants: A Real-World Analysis
40. Plasma Membrane Translocation of Fluorescent-Labeled Phosphatidylethanolamine Is Controlled by Transcription Regulators, PDR1 and PDR3
41. Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells
42. Insights from integrating clinical and preclinical studies advance understanding of graft-versus-host disease
43. Figure S3 from Chimeric Antigen Receptor T Cell–Mediated Neurotoxicity in Nonhuman Primates
44. Data from Chimeric Antigen Receptor T Cell–Mediated Neurotoxicity in Nonhuman Primates
45. Table S2 from Chimeric Antigen Receptor T Cell–Mediated Neurotoxicity in Nonhuman Primates
46. Pre-existing immunity does not impair the engraftment of electroporation-mediated RNP CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation
47. CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire
48. Author Correction: Innovations present in the primate interneuron repertoire
49. Abatacept for the Prevention of Graft Versus Host Disease in Pediatric Patients Receiving 7/8 HLA-Mismatched Unrelated Transplant for Hematologic Malignancies: A Real-World Analysis
50. Single-Cell RNA-Seq Reveals an Interferon-Driven Inflammatory CD4 Naïve T Cell Subpopulation at Day 100 in Hematopoietic Stem Cell Transplant Patients That Ultimately Develop Chronic Gvhd
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