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Rationale and Objectives The aim of this study was to determine whether resident performance in head ultrasound on neonates improves following brain phantom simulation training. Materials and Methods Ten junior radiology residents with at least one year of radiology training were divided into two equal groups. Both groups received a detailed head ultrasound protocol sheet and observed a technologist perform a head ultrasound on a neonatal patient at the beginning of their first pediatric radiology rotation. Both groups of residents also received teaching with a brain phantom model. Group A residents independently performed one head ultrasound exam, subsequently received phantom simulation training, and then performed a post-training head ultrasound exam. Group B residents received phantom simulation training prior to their first head ultrasound exam. Three pediatric radiologists independently and blindly reviewed the ultrasound images of each head ultrasound exam for proficiency of image acquisition using a validated scoring system. Scores of Group A residents prior to phantom training were compared to their scores after phantom training as well as to scores of Group B residents using simple linear regression. Results There was a statistically significant improvement in the performance of head ultrasound on neonates when comparing the same residents pre- and postphantom training (p = 0.003). Residents who initially trained with the phantom performed significantly better on their first head ultrasound examination on a neonate than those residents who did not (p = 0.005). Conclusion Our novel head ultrasound phantom training model significantly improves radiology resident performance of head ultrasound on neonates and may, therefore, be beneficial for residency education.

The present work deals with the experimental and numerical investigation of melting process of phase change material used for low temperature thermal energy storage applications. Thermal energy storage is a good solution to bridge the gap between energy supply and energy demand. The unconstrained melting of paraffin wax having melting range of 570C to 610C was studied in simple spherical glass capsule. The objective of the subject work is to perform the experimental and numerical analysis of melting process in spherical capsule subjected to constant wall temperature. Ansys Fluent 18 is used for computation purpose. In experimental analysis, melting process was observed through visual capturing of interface between solid and liquid. Melting fraction and temperature at the centre of PCM capsule are monitored both experimentally and numerically. Good consistency in results were observed.

OBJECTIVE. Our objective was to evaluate the diagnostic accuracy and reliability of MRI and its ability to depict responsiveness to treatment for the evaluation of the axial joints (temporomandibular joint [TMJ], spinal joints, and sacroiliac joints) in juvenile idiopathic arthritis (JIA). CONCLUSION. There is fair (grade B) evidence that MRI is an accurate diagnostic method for evaluating early and intermediate changes in the TMJ in JIA and insufficient evidence to indicate MRI is an accurate diagnostic method for detecting JIA in the spinal (grade I) and sacroiliac (grade I) joints.

In medical field there is a growing need for development of software to be used for practical applications rather than only in research field. Doctors need not only to know the main symptoms in a patient but also the other factors in life and surrounding that lead to disease in the patient. For collecting all the necessary information about the patient the doctors needs to spend a lot of time with the patient asking necessary questions to get the important details. The doctor needs to document all the data for further use and needs to keep track of all the patient details and remedies. The proposed system is intended to develop an Intelligent System using data mining modeling technique, namely, Naive Bayes. It is implemented as Java application in which user answers the predefined questions. It retrieves hidden data from stored database and compares the user values with trained data set. It can answer complex queries for diagnosing heart disease and thus assist healthcare practitioners to make intelligent clinical decisions which traditional decision support systems cannot.

This paper derives all necessary equations which require for modeling of PMSG. The generator model is established in the dq-synchronous rotating reference frame. A MATLAB/Simulink simulation has been developed using 8.5 KW permanent magnet synchronous generator. In this paper maximum power point tracking (MPPT) controller for variable speed wind turbine is proposed. Maximum power which a wind turbine can deliver at a certain wind speed depends upon certain optimum value of speed at which the shaft rotates. Only at optimum speed we can have efficient use of equipment and available energy source. In order to control a wind turbine with Permanent Magnet Synchronous Generator (PMSG), a set of full-scale back-to-back voltage converter is used. The back-to-back converters are connected through a DC-link capacitor. The capacitor decouples the two converters, allowing separate controls being applied to each converter for simplicity. The control systems are separated into generator-side controller and grid-side controller. In this arrangement, the generator-side converter controls the operation of the generator and the network-side converter controls the DC link voltage by exporting active power to the network.

Wind turbine generator has been popular in the area of renewable energy source. Wind Turbine generator has shown the biggest growth in the past 10 years compared to other renewable sources. Direct drive generator using Permanent Magnet Synchronous Generator (PMSG) is used now a days as variable speed wind turbine generator. PMSG is suitable for the application due to its high efficiency, high torque-to size ratio, and low maintenance requirement. This paper derives all necessary equations which require for modeling of PMSG. The generator model is established in the dq-synchronous rotating reference frame. In this Paper MATLAB/Simulink simulation has been developed using 6 KW permanent magnet synchronous Generator. In order to verify the presented model simulations with MATLAB/Simulink software have been conducted. Simulation results prove the validity of the model.

The destabilization of endothelial nitric-oxide synthase (eNOS) mRNA in hypoxic endothelial cells may be important in the etiology of vascular diseases, such as pulmonary hypertension. Recently, an overlapping antisense transcript to eNOS/NOS3 was implicated in the post-transcriptional regulation of eNOS. We demonstrate here that expression of sONE, also known as eNOS antisense (NOS3AS) or autophagy 9-like 2 (APG9L2), is robustly induced by hypoxia or functional deficiency of von Hippel-Lindau protein. sONE is also up-regulated in the aortas of hypoxic rats. In hypoxic endothelial cells, sONE expression negatively correlates with eNOS expression. Blocking the hypoxic induction of sONE by RNA interference attenuates the fall in both eNOS RNA and protein. We provide evidence that the induction of sONE primarily involves transcript stabilization rather than increased transcriptional activity and is von Hippel-Lindaubut not hypoxia-inducible factor 2alpha-dependent. We also demonstrate that sONE transcripts are enriched in the nucleus of normoxic cells and that hypoxia promotes an increase in the level of cytoplasmic and polyribosome-associated, sONE mRNA. The finding that eNOS expression can be regulated by an overlapping cis-antisense transcript in a stimulus-dependent fashion provides evidence that sense/antisense interactions may play a previously unappreciated role in vascular disease pathogenesis.

The Dicer enzyme is a key component of the RNA interference pathway and also responsible for the processing of micro RNAs, non-coding RNA molecules which regulate the activity of mRNAs by antisense base pairing. Little is known about the structure and regulation of human Dicer mRNA. A comprehensive characterization of Dicer 5′-untranslated region (5′-UTR) RNA structure revealed important diversity within human Dicer mRNA transcripts. Three exon 1 variants were defined, some of which exhibited very restricted patterns of tissue distribution. A number of alternatively spliced 5′-leader exons were also noted, revealing the potential for complex post-transcriptional regulation. Surprisingly, this diversity all occurred within the 5′-UTR of Dicer mRNAs and did not affect the coding region. The Dicer mRNA 5′-UTR variants had profound effects on translational efficiency both in vitro and in transiently transfected cells. A number of major Dicer RNA species are inefficient substrates for the translational machinery.

[Figure][1] Image courtesy of ©2010 Jupiterimages Corp. > I try and spy with my little eye, > > Your age, your sex, the name you go by, > > The type of exam, position you’re in, > > Comparison films? Oh good, let’s begin. > Next time can you take a bigger “big breath?” > > I