Search

Chernet Tafere,1 Bereket Bahiru Tefera,2 Adane Yehualaw,1 Desalegn Getnet Demsie,3 Belayneh Kefale,4 Kebede Feyisa,5 Malede Berihun Yismaw,4 Endalamaw Aschale,4 Zenaw Debasu,4 Zewdu Yilma,1 Zegaye Agmassie,4 Ibrahim Abdela Siraj,1 Ashagrachew Tewabe Yayehrad,1 Sileshi Mulatu,6 Destaw Endeshaw7 1Department of Pharmaceutics, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Amhara, Ethiopia; 2Department of Social Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Amhara, Ethiopia; 3Department of Pharmacology, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Amhara, Ethiopia; 4Department of Clinical Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Amhara, Ethiopia; 5Department of Pharmacognosy, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Amhara, Ethiopia; 6Department of Pediatrics and Child Health Nursing, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Amhara, Ethiopia; 7Department of Adult health Nursing, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Amhara, EthiopiaCorrespondence: Chernet Tafere, Tel +251924524636, Email cheru004@gmail.comBackground: Opioid use is a major global public health problem, affecting 16 million individuals worldwide. According to a 2023 WHO report, out of the 600,000 substance-related deaths worldwide, 80% were attributed to opioid use. Pharmacists play a vital role in reducing unnecessary opioid exposure while facilitating access to non-opioid alternatives. To do so, pharmacists should have sufficient knowledge regarding opioid-containing medications and a positive attitude about opioid use problems.Objective: This study aimed to evaluate community pharmacists’ knowledge of opioid-containing medications and their attitude toward opioid use problems.Materials and methods: A cross-sectional study was conducted using a self-administered, str

Malede Berihun Yismaw, Kebede Feyisa, Adane Yehualaw, Chernet Tafere, Desalegn Getnet Demsie, Bereket Bahiru, Belayneh Kefale Department of Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, EthiopiaCorrespondence: Malede Berihun Yismaw, Department of Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, PO Box 79, Bahir Dar, Ethiopia, Tel +251966335852, Email malepharm@gmail.comBackground: Self-medication (SM) is the use of drugs or herbs to treat self-diagnosed physical ailments or symptoms without consulting a healthcare professional. It plays a great role in daily life and common in the healthcare system around the globe, especially in developing countries. Due to their expertise, health science students are also predicted to practice it more frequently.Objective: To evaluate the use of SM and its determinants among undergraduate health science students at the College of Medicine and Health Sciences, Bahir Dar University, North West Ethiopia.Methods: 241 students took part in the study from September to November 2021. Using a recall time of four weeks, a quantitative descriptive cross-sectional study was utilized to evaluate the practice of self-medication and associated factors. Interviews and structured questionnaires were used to collect the data. Data were analyzed using SPSS version 25.Results: Overall, 246 students were approached. The questionnaire received responses from 241 students, for a 98% response rate. Self-medication was used by 58.1% of students over the course of the previous four weeks. Analgesic and antipyretic medications were the most often utilized pharmacological category (57.1%), followed by antibiotics (42.1%). The most frequent (50%) complaints involving SM were headache and fever. The mildness of the sickness was the primary factor in the study participants’ practice of self-medication (50%). Self-medication is linked to gender (AOR: 3.415; 95% CI: 1.014– 11.503), poor monthly in

Belayneh Kefale,1 Melaku Tadege Engidaw,2 Desalegn Tesfa,2 Mulugeta Molla,3 Malede Berihun Yismaw1 1Clinical Pharmacy Unit and Research Team, Department of Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Amhara, Ethiopia; 2Department of Social and Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia; 3Pharmacology and Toxicology Unit, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, EthiopiaCorrespondence: Belayneh Kefale, Clinical Pharmacy and Research Unit, Department of Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Amhara, Ethiopia, Email bkefale5@gmail.comIntroduction: In cervical cancer therapy, there is a high prevalence of drug-related problems (DRPs) due to the high toxicity and complexity of most antineoplastic regimens. However, there is a paucity of data about DRPs among patients with cervical cancer in Ethiopia. Hence, the present study was aimed at investigating management practices and DRPs among patients diagnosed with cervical cancer.Methods: A registry-based retrospective cohort study was employed among cervical cancer patients at the oncology center of Felege Hiwot Comprehensive Specialized Hospital (FHCSH). All patients with a histologically confirmed diagnosis of cervical cancer from January 2016 to December 2020 were included. Relevant information was recorded by reviewing medical records. The possibility of DRPs was evaluated by comparing with standard guidelines. Logistic regression analysis was employed.Results: A total of 184 cervical cancer patients were included, with a mean age of 50.2± 10.7 years. A total of 216 DRPs were identified from 93 cervical cancer patients, translating to a prevalence of 50.5% and a mean of 2.32± 1.11 DRPs per patient. ADR (27.3%), DDI (25%), and the need for additional drug therapy (22.2%) were the most prevalent DRPs. DRPs were associated with t

Amien Ewunetei,1 Hiwot Yisak,2 Belayneh Kefale1 1Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia; 2Department of Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaCorrespondence: Amien EwuneteiDepartment of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, 272, EthiopiaTel +251913670582Email amienpeace@gmail.comIntroduction: Inappropriate drug utilization may reduce the best possible benefits of drug therapy, and patients may not be cured, they may be exposed to toxicity, and medications may be wasted. The aim of this study is to assess household-level drug utilization practices and their associated factors.Methods: A cross-sectional community-based study was conducted from January 15 to March 15, 2020. In total, 847 households selected by stratified multistage sampling were visited. Bivariate and multivariable analyses for association were carried out using a binary logistic regression model. The statistical significance of an association was confirmed at p< 0.05.Results: Of the total 847 households, 378 (44.6%) were found to store drugs at home at the time of datacollection. In the 371 households that allowed observation of the drugs stored, a mean of 2.51 (SD=1.68) drugs per household was found; 40.2% of stored medicines were not in use at the time of the study. The prevalences of medication hoarding, sharing, and allopathic self-medication were 20.4%, 26.3%, and 43.8%, respectively. Higher monthly income and the presence of a child aged under 5 years were significantly associated with drug hoarding. The presence of an elderly person aged above 65 years and the presence of a family member with chronic illness were significantly associated with drug hoarding and sharing. Families with higher educational status were less likely to hoard and share medicines. The presence of stored drugs at home was significantly associated with the practice of self

Belayneh Kefale,1 Gobezie T Tegegne,2 Amsalu Degu,3 Mulugeta Molla,4 Yitayih Kefale5 1Clinical Pharmacy Unit and Research Team, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia; 2Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 3Department of Pharmaceutics and Pharmacy Practice, School of Pharmacy and Health Sciences, United States International University-Africa, Nairobi, Kenya; 4Pharmacology and Toxicology Unit and Research Team, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia; 5Clinical Pharmacy Unit, Department of Pharmacy, Bahir Dar Health Sciences College, Bahir Dar, Amhara, EthiopiaCorrespondence: Belayneh KefaleClinical Pharmacy Unit and Research Team, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, EthiopiaTel +251913805289Email bkefale5@gmail.comObjective: Surgical site infection (SSI) is one of the leading causes of hospital-acquired infection among hospitalized patients. It causes significant health problems and results in an extended length of hospital stay, increased cost, and increased patient morbidity and mortality. To prevent the development of SSI, surgical antibiotic prophylaxis (SAP) administration before surgery is an evidence-based practice. Therefore, this study aimed to assess the prevalence of SSIs and surgical antibiotic prophylaxis practice, and identifying the gap in practicing prophylactic surgical antibiotic use.Methods: A retrospective cross-sectional study design was conducted on randomly selected 281 participants who fulfilled the inclusion criteria. Appropriateness of surgical antibiotic prophylaxis was assessed by clinical pharmacists based on the standard treatment guideline. Descriptive and multivariate logistic regression analyses were performed in SPSS version 25. Statist

Tesfaye Molla Gulentie,1 Ebrahim Mohammed Yesuf,2 Taklo Simeneh Yazie,3 Belayneh Kefale4 1Department of Drug Distribution, Pharmaceutical Fund and Supply Agency, Samara, Ethiopia; 2Department of Public Health, Samara University, Samara, Ethiopia; 3Pharmacology Unit and Research Team, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Amhara, Ethiopia; 4Clinical Pharmacy Unit and Research Team, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Amhara, EthiopiaCorrespondence: Belayneh KefaleClinical Pharmacy Unit and Research Team, Department of Pharmacy, College of Health Sciences, Debre Tabor University, PO Box 272, Debre Tabor, Amhara, EthiopiaTel +251 913805289/90Email bkefale5@gmail.comObjective: Even though life-threatening complications in type 2 diabetes mellitus (T2DM) minimize through self-care practice, extensive studies in northeast Ethiopia have been scarce about self-care practice and predictors. This study aimed to assess diabetes self-care predictors among patients with T2DM patients at Dubti and Assaita hospitals in northeastern Ethiopia.Methods: A facility-based cross-sectional study was conducted among 403 patients with T2DM who followed-up in northeastern Ethiopia’s Dubti and Assaita hospitals. Data were analyzed using SPSS version-22.0 after the data were entered, sorted and cleaned. Multiple stepwise backward logistic regression analysis was done for a P value of < 0.25 to identify the independent predictors of self-care practice.Results: In the present study, males comprised 62% of the sex category. Overall, 63.8% of the study participants had adequate self-care practice, while 36.2% had inadequate self-care practice. Being younger age (AOR 2.27, 95% CI 1.27– 4.07, P= 0.005), monthly income status with low (AOR 3.08, 95% CI 1.08– 8.78, P= 0.04), average (AOR 2.43, 95% CI 1.15– 5.09, P= 0.02) and high (AOR 2.68, 95% CI 1.03– 6.99, P= 0.04)