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2. Trends in Distal Esophageal and Gastroesophageal Junction Cancer Care: The Dutch Nationwide Ivory Study

Author

Kalff, Marianne C., van Berge Henegouwen, Mark I., Baas, Peter C., Bahadoer, Renu R., Belt, Eric J. T., Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D., Dekker, Jan Willem T., van Det, Marc J., Drost, Manon, van Duijvendijk, Peter, Eshuis, Wietse J., van Esser, Stijn, Gaspersz, Marcia P., Görgec, Burak, Groenendijk, Richard P. R., Hartgrink, Henk H., van der Harst, Erwin, Haveman, Jan Willem, Heisterkamp, Joos, van Hillegersberg, Richard, Kelder, Wendy, Kingma, B. Feike, Koemans, Willem J., Kouwenhoven, Ewout A., Lagarde, Sjoerd M., Lecot, Frederik, van der Linden, Philip P., Luyer, Misha D. P., Nieuwenhuijzen, Grard A. P., Olthof, Pim B., van der Peet, Donald L., Pierie, Jean-Pierre E. N., Pierik, E. G. J. M. Robert, Plat, Victor D., Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P., van Sandick, Johanna W., Scheer, Rene, Slootmans, Cettela A. M., Sosef, Meindert N., Sosef, Odin V., de Steur, Wobbe O., Stockmann, Hein B. A. C., Stoop, Fanny J., Voeten, Daan M., Vugts, Guusje, Vijgen, Guy H. E. J., Weeda, Víola B., Wiezer, Marinus J., van Oijen, Martijn G. H., and Gisbertz, Suzanne S.

Published
2023
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4. Recurrent Disease After Esophageal Cancer Surgery: A Substudy of The Dutch Nationwide Ivory Study

Author

Kalff, Marianne C., Henckens, Sofie P.G., Voeten, Daan M., Heineman, David J., Hulshof, Maarten C.C.M., van Laarhoven, Hanneke W.M., Eshuis, Wietse J., Baas, Peter C., Bahadoer, Renu R., Belt, Eric J.T., Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D., Dekker, Jan Willem T., van Det, Marc J., Drost, Manon, van Duijvendijk, Peter, van Esser, Stijn, Gaspersz, Marcia P., Görgec, Burak, Groenendijk, Richard P.R., Hartgrink, Henk H., van der Harst, Erwin, Haveman, Jan W., Heisterkamp, Joos, van Hillegersberg, Richard, Kelder, Wendy, Kingma, B. Feike, Koemans, Willem J., Kouwenhoven, Ewout A., Lagarde, Sjoerd M., Lecot, Frederik, van der Linden, Philip P., Luyer, Misha D.P., Nieuwenhuijzen, Grard A.P., Olthof, Pim B., van der Peet, Donald L., Pierie, Jean-Pierre E.N., Pierik, E.G.J.M. Robert, Plat, Victor D., Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P., van Sandick, Johanna W., Scheer, Rene, Slootmans, Cettela A.M., Sosef, Meindert N., Sosef, Odin V., de Steur, Wobbe O., Stockmann, Hein B.A.C., Stoop, Fanny J., Vugts, Guusje, Vijgen, Guy H.E.J., Weeda, Víola B., Wiezer, Marinus J., van Oijen, Martijn G.H., van Berge Henegouwen, Mark I., and Gisbertz, Suzanne S.

Published
2022
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6. Trends in Distal Esophageal and Gastroesophageal Junction Cancer Care: The Dutch Nationwide Ivory Study

Author

Kalff, Marianne C., Henegouwen, Mark I. van Berge, Baas, Peter C., Bahadoer, Renu R., Belt, Eric J. T., Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D., Dekker, Jan Willem T., van Det, Marc J., Drost, Manon, van Duijvendijk, Peter, Eshuis, Wietse J., van Esser, Stijn, Gaspersz, Marcia P., Görgec, Burak, Groenendijk, Richard P. R., Hartgrink, Henk H., van der Harst, Erwin, Haveman, Jan Willem, Heisterkamp, Joos, van Hillegersberg, Richard, Kelder, Wendy, Kingma, B. Feike, Koemans, Willem J., Kouwenhoven, Ewout A., Lagarde, Sjoerd M., Lecot, Frederik, van der Linden, Philip P., Luyer, Misha D. P., Nieuwenhuijzen, Grard A. P., Olthof, Pim B., van der Peet, Donald L., Pierie, Jean-Pierre E. N., Pierik, E. G. J. M. Robert, Plat, Victor D., Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P., van Sandick, Johanna W., Scheer, Rene, Slootmans, Cettela A. M., Sosef, Meindert N., Sosef, Odin V., de Steur, Wobbe O., Stockmann, Hein B. A. C., Stoop, Fanny J., Voeten, Daan M., Vugts, Guusje, Vijgen, Guy H. E. J., Weeda, Víola B., Wiezer, Marinus J., van Oijen, Martijn G. H., and Gisbertz, Suzanne S.

Published
2021
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8. Head-to-head comparison of [11C]methionine PET, [11C]choline PET, and 4-dimensional CT as second-line scans for detection of parathyroid adenomas in primary hyperparathyroidism

Author

Noltes, Milou E., primary, Kruijff, Schelto, additional, Appelman, Auke P. A., additional, Jansen, Liesbeth, additional, Zandee, Wouter T., additional, Links, Thera P., additional, van Hemel, Bettien M., additional, Schouw, Hugo M., additional, Dierckx, Rudi A. J. O., additional, Francken, Anne Brecht, additional, Kelder, Wendy, additional, van der Hoorn, Anouk, additional, and Brouwers, Adrienne H., additional

Published
2023
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9. Head-to-head comparison of [11C]methionine PET, [11C]choline PET, and 4-dimensional CT as second-line scans for detection of parathyroid adenomas in primary hyperparathyroidism.

Author

Noltes, Milou E., Kruijff, Schelto, Appelman, Auke P. A., Jansen, Liesbeth, Zandee, Wouter T., Links, Thera P., van Hemel, Bettien M., Schouw, Hugo M., Dierckx, Rudi A. J. O., Francken, Anne Brecht, Kelder, Wendy, van der Hoorn, Anouk, and Brouwers, Adrienne H.

Subjects
PARATHYROID glands, POSITRON emission tomography, COMPUTED tomography, ADENOMA, METHIONINE, CHOLINE, HYPERPARATHYROIDISM
Abstract

Purpose: Accurate preoperative localization is imperative to guide surgery in primary hyperparathyroidism (pHPT). It remains unclear which second-line imaging technique is most effective after negative first-line imaging. In this study, we compare the diagnostic effectiveness of [11C]methionine PET/CT, [11C]choline PET/CT, and four dimensional (4D)-CT head-to-head in patients with pHPT, to explore which of these imaging techniques to use as a second-line scan. Methods: We conducted a powered, prospective, blinded cohort study in patients with biochemically proven pHPT and prior negative or discordant first-line imaging consisting of ultrasonography and 99mTc-sestamibi. All patients underwent [11C]methionine PET/CT, [11C]choline PET/CT, and 4D-CT. At first, all scans were interpreted by a nuclear medicine physician, and a radiologist who were blinded from patient data and all imaging results. Next, a non-blinded scan reading was performed. The scan results were correlated with surgical and histopathological findings. Serum calcium values at least 6 months after surgery were used as gold standard for curation of HPT. Results: A total of 32 patients were included in the study. With blinded evaluation, [11C]choline PET/CT was positive in 28 patients (88%), [11C]methionine PET/CT in 23 (72%), and 4D-CT in 15 patients (47%), respectively. In total, 30 patients have undergone surgery and 32 parathyroid lesions were histologically confirmed as parathyroid adenomas. Based on the blinded evaluation, lesion-based sensitivity of [11C]choline PET/CT, [11C]methionine PET/CT, and 4D-CT was respectively 85%, 67%, and 39%. The sensitivity of [11C]choline PET/CT differed significantly from that of [11C]methionine PET/CT and 4D-CT (p = 0.031 and p < 0.0005, respectively). Conclusion: In the setting of pHPT with negative first-line imaging, [11C]choline PET/CT is superior to [11C]methionine PET/CT and 4D-CT in localizing parathyroid adenomas, allowing correct localization in 85% of adenomas. Further studies are needed to determine cost–benefit and efficacy of these scans, including the timing of these scans as first- or second-line imaging techniques. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Erratum to “Practice variation in anastomotic leak after esophagectomy: Unravelling differences in failure to rescue” [Eur J Surg Oncol 49 (5) (May 2023) 974–982]

Author

Ubels, Sander, primary, Matthée, Eric, additional, Verstegen, Moniek, additional, Klarenbeek, Bastiaan, additional, Bouwense, Stefan, additional, van Berge Henegouwen, Mark I., additional, Daams, Freek, additional, Dekker, Jan Willem T., additional, van Det, Marc J., additional, van Esser, Stijn, additional, Griffiths, Ewen A., additional, Haveman, Jan Willem, additional, Nieuwenhuijzen, Grard, additional, Siersema, Peter D., additional, Wijnhoven, Bas, additional, Hannink, Gerjon, additional, van Workum, Frans, additional, Rosman, Camiel, additional, Heisterkamp, Joos, additional, Polat, Fatih, additional, Schouten, Jeroen, additional, Singh, Pritam, additional, Slootmans, Cettela A.M., additional, Ultee, Gijs, additional, Gisbertz, Suzanne S., additional, Eshuis, Wietse J., additional, Kalff, Marianne C., additional, Feenstra, Minke L., additional, van der Peet, Donald L., additional, Stam, Wessel T., additional, Van Etten, Boudewijn, additional, Poelmann, Floris, additional, Vuurberg, Nienke, additional, Willem van den Berg, Jan, additional, Martijnse, Ingrid S., additional, Matthijsen, Robert M., additional, Luyer, Misha, additional, Curvers, Wout, additional, Nieuwenhuijzen, Tom, additional, Taselaar, Annick E., additional, Kouwenhoven, Ewout A., additional, Lubbers, Merel, additional, Sosef, Meindert, additional, Lecot, Frederik, additional, Geraedts, Tessa C.M., additional, van den Wildenberg, Frits, additional, Kelder, Wendy, additional, Baas, Peter C., additional, de Haas, Job W.A., additional, Hartgrink, Henk H., additional, Bahadoer, Renu R., additional, van Sandick, Johanna W., additional, Hartemink, Koen J., additional, Veenhof, Xander, additional, Stockmann, Hein, additional, Gorgec, Burak, additional, Weeder, Pepijn, additional, Wiezer, Marinus J., additional, Genders, Charlotte M.S., additional, Belt, Eric, additional, Blomberg, Bjorn, additional, van Duijvendijk, Peter, additional, Claassen, Linda, additional, Reetz, David, additional, Steenvoorde, Pascal, additional, Mastboom, Walter, additional, Klein Ganseij, Henk Jan, additional, van Dalsen, Annette D., additional, Joldersma, Annalie, additional, Zwakman, Marije, additional, Groenendijk, Richard P.R., additional, Montazeri, Mahsa, additional, Mercer, Stuart, additional, Knight, Benjamin, additional, van Boxel, Gijs, additional, McGregor, Richard J., additional, Skipworth, Richard J.E., additional, Frattini, Cristina, additional, Bradley, Alice, additional, Nilsson, Magnus, additional, Hayami, Masaru, additional, Huang, Biying, additional, Bundred, James, additional, Evans, Richard, additional, Grimminger, Peter P., additional, van der Sluis, Pieter C., additional, Eren, Uzun, additional, Saunders, John, additional, Theophilidou, Elena, additional, Khanzada, Zubair, additional, Elliott, Jessie A., additional, Ponten, Jeroen, additional, King, Sinead, additional, Reynolds, John V., additional, Sgromo, Bruno, additional, Akbari, Khalid, additional, Shalaby, Samar, additional, Gutschow, Christian A., additional, Schmidt, Henner, additional, Vetter, Diana, additional, Moorthy, Krishna, additional, Ibrahim, Mohamed A.H., additional, Christodoulidis, Grigorious, additional, Räsänen, Jari V., additional, Kauppi, Juha, additional, Söderström, Henna, additional, Koshy, Renol, additional, Manatakis, Dimitrios K., additional, Korkolis, Dimitrios P., additional, Balalis, Dimitrios, additional, Rompu, Aliki, additional, Alkhaffaf, Bilal, additional, Alasmar, Mohamed, additional, Arebi, Moaad, additional, Piessen, Guillaume, additional, Nuytens, Frederiek, additional, Degisors, Sebastien, additional, Ahmed, Ahmed, additional, Boddy, Alex, additional, Gandhi, Suraj, additional, Fashina, Oluwatomini, additional, Van Daele, Elke, additional, Pattyn, Piet, additional, Robb, William B., additional, Arumugasamy, Mayilone, additional, Al Azzawi, Mohammed, additional, Whooley, Jack, additional, Colak, Elif, additional, Aybar, Engin, additional, Sari, Ahmet C., additional, Uyanik, Mustafa S., additional, Ciftci, Ahmet B., additional, Sayyed, Raza, additional, Ayub, Bushra, additional, Murtaza, Ghulam, additional, Saeed, Aniqa, additional, Ramesh, Priyanka, additional, Charalabopoulos, Alexandros, additional, Liakakos, Theodore, additional, Schizas, Dimitrios, additional, Baili, Efstratia, additional, Kapelouzou, Alkistis, additional, Valmasoni, Michele, additional, Pierobon, Elisa Sefora, additional, Capovilla, Giovanni, additional, Merigliano, Stefano, additional, Constantinoiu, Silviu, additional, Birla, Rodica, additional, Achim, Florin, additional, Rosianu, Cristian Gelu, additional, Hoara, Petre, additional, Castro, Raúl Guevara, additional, Salcedo, Andrés Felipe, additional, Negoi, Ionut, additional, Negoita, Valentina M., additional, Ciubotaru, Cezar, additional, Stoica, Bogdan, additional, Hostiuc, Sorin, additional, Colucci, Nicola, additional, Mönig, Stefan P., additional, Wassmer, Charles-Henri, additional, Meyer, Jeremy, additional, Takeda, Flavio Roberto, additional, Aissar Sallum, Rubens Antonio, additional, Ribeiro, Ulysses, additional, Cecconello, Ivan, additional, Toledo, Enrique, additional, Trugeda, Maria Soledad, additional, Fernández, María José, additional, Gil, Carolina, additional, Castanedo, Sonia, additional, Isik, Arda, additional, Kurnaz, Eray, additional, Videira, José Flávio, additional, Peyroteo, Mariana, additional, Canotilho, Rita, additional, Weindelmayer, Jacopo, additional, Giacopuzzi, Simone, additional, De Pasqual, Carlo Alberto, additional, Bruna, Marcos, additional, Mingol, Fernando, additional, Vaque, Javier, additional, Pérez, Carla, additional, Phillips, Alexander W., additional, Chmelo, Jakub, additional, Brown, Joshua, additional, Han, Laura E., additional, Gossage, James A., additional, Davies, Andrew R., additional, Baker, Cara R., additional, Kelly, Mark, additional, Saad, Mohamed, additional, Bernardi, Daniele, additional, Bonavina, Luigi, additional, Asti, Emanuele, additional, Riva, Carlo, additional, Scaramuzzo, Rosa, additional, Elhadi, Muhammed, additional, Ahmed, Hazem Abdelkarem, additional, Elhadi, Ahmed, additional, Elnagar, Faruk Ali, additional, Msherghi, Ahmed A.A., additional, Wills, Vanessa, additional, Campbell, Cassidy, additional, Cerdeira, Marisol Perez, additional, Whiting, Scott, additional, Merrett, Neil, additional, Das, Amitabha, additional, Apostolou, Christos, additional, Lorenzo, Aldenb, additional, Sousa, Fabiana, additional, Barbosa, José Adelino, additional, Devezas, Vítor, additional, Barbosa, Elisabete, additional, Fernandes, Cristina, additional, Smith, Garett, additional, Li, Edward Y., additional, Bhimani, Nazim, additional, Chan, Priscilla, additional, Kotecha, Krishna, additional, Hii, Michael W., additional, Ward, Salena M., additional, Johnson, MaryAnn, additional, Read, Matthew, additional, Chong, Lynn, additional, Hollands, Michael J., additional, Allaway, Matthew, additional, Richardson, Arthur, additional, Johnston, Emma, additional, Chen, Andy Z.L., additional, Kanhere, Harsh, additional, Prasad, Shalvin, additional, McQuillan, Patrick, additional, Surman, Tim, additional, Trochsler, MarkusI., additional, Schofield, W.A., additional, Ahmed, Syeda Khadijah, additional, Reid, Jessica L., additional, Harris, Mark C., additional, Gananadha, Sivakumar, additional, Farrant, Jessica, additional, Rodrigues, Nicole, additional, Fergusson, James, additional, Hindmarsh, Andrew, additional, Afzal, Zeeshan, additional, Safranek, Peter, additional, Sujendran, Vijay, additional, Rooney, Siobhan, additional, Loureiro, Carlos, additional, Fernández, Saioa Leturio, additional, Díez del Val, Ismael, additional, Jaunoo, Shameen, additional, Kennedy, Lauren, additional, Hussain, Ahmed, additional, Theodorou, Dimitrios, additional, Triantafyllou, Tania, additional, Theodoropoulos, Charalampos, additional, Palyvou, Theodora, additional, Ben Taher, Fatima Abdullah, additional, and Ekheel, Mustafa, additional

Published
2023
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12. Diagnostic Accuracy of Radioactive Iodine Seed Placement in the Axilla With Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Node-Positive Breast Cancer

Author

Simons, Janine M., van Nijnatten, Thiemo J. A., van der Pol, Carmen C., van Diest, Paul J., Jager, Agnes, van Klaveren, David, Kam, Boen L. R., Lobbes, Marc B., de Boer, Maaike, Verhoef, Cees, Sars, Paul R. A., Heijmans, Harald J., van Haaren, Els R. M., Vles, Wouter J., Contant, Caroline M. E., Menke-Pluijmers, Marian B. E., Smit, Leonie H. M., Kelder, Wendy, Boskamp, Marike, Koppert, Linetta B., Luiten, Ernest J. T., Smidt, Marjolein L., RS: GROW - R2 - Basic and Translational Cancer Biology, Surgery, MUMC+: DA BV AIOS Radiologie (9), Beeldvorming, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Interne Geneeskunde, MUMC+: MA Medische Oncologie (9), MUMC+: MA Heelkunde (9), Radiotherapy, Medical Oncology, Public Health, and Radiology & Nuclear Medicine

Subjects
Sentinel Lymph Node Biopsy, Breast Neoplasms, Middle Aged, Neoadjuvant Therapy, Iodine Radioisotopes, SDG 3 - Good Health and Well-being, Lymphatic Metastasis, Axilla, Humans, Lymph Node Excision, Surgery, Female, Prospective Studies, Thyroid Neoplasms, Lymph Nodes, Sentinel Lymph Node, Iodine
Abstract

ImportanceSeveral less-invasive staging procedures have been proposed to replace axillary lymph node dissection (ALND) after neoadjuvant chemotherapy (NAC) in patients with initially clinically node-positive (cN+) breast cancer, but these procedures may fail to detect residual disease. Owing to the lack of high-level evidence, it is not yet clear which procedure is most optimal to replace ALND.ObjectiveTo determine the diagnostic accuracy of radioactive iodine seed placement in the axilla with sentinel lymph node biopsy (RISAS), a targeted axillary dissection procedure.Design, Setting, and ParticipantsThis was a prospective, multicenter, noninferiority, diagnostic accuracy trial conducted from March 1, 2017, to December 31, 2019. Patients were included within 14 institutions (general, teaching, and academic) throughout the Netherlands. Patients with breast cancer clinical tumor categories 1 through 4 (cT1-4; tumor diameter 5 cm or extension to the chest wall or skin) and pathologically proven positive axillary lymph nodes (ie, clinical node categories cN1, metastases to movable ipsilateral level I and/or level II axillary nodes; cN2, metastases to fixed or matted ipsilateral level I and/or level II axillary nodes; cN3b, metastases to ipsilateral level I and/or level II axillary nodes with metastases to internal mammary nodes) who were treated with NAC were eligible for inclusion. Data were analyzed from July 2020 to December 2021.InterventionPre-NAC, the marking of a pathologically confirmed positive axillary lymph node with radioactive iodine seed (MARI) procedure, was performed and after NAC, sentinel lymph node biopsy (SLNB) combined with excision of the marked lymph node (ie, RISAS procedure) was performed, followed by ALND.Main Outcomes and MeasuresThe identification rate, false-negative rate (FNR), and negative predictive value (NPV) were calculated for all 3 procedures: RISAS, SLNB, and MARI. The noninferiority margin of the observed FNR was 6.25% for the RISAS procedure.ResultsA total of 212 patients (median [range] age, 52 [22-77] years) who had cN+ breast cancer underwent the RISAS procedure and ALND. The identification rate of the RISAS procedure was 98.2% (223 of 227). The identification rates of SLNB and MARI were 86.4% (197 of 228) and 94.1% (224 of 238), respectively. FNR of the RISAS procedure was 3.5% (5 of 144; 90% CI, 1.38-7.16), and NPV was 92.8% (64 of 69; 90% CI, 85.37-97.10), compared with an FNR of 17.9% (22 of 123; 90% CI, 12.4%-24.5%) and NPV of 72.8% (59 of 81; 90% CI, 63.5%-80.8%) for SLNB and an FNR of 7.0% (10 of 143; 90% CI, 3.8%-11.6%) and NPV of 86.3% (63 of 73; 90% CI, 77.9%-92.4%) for the MARI procedure. In a subgroup of 174 patients in whom SLNB and the MARI procedure were successful and ALND was performed, FNR of the RISAS procedure was 2.5% (3 of 118; 90% CI, 0.7%-6.4%), compared with 18.6% (22 of 118; 90% CI, 13.0%-25.5%) for SLNB (P P = .03).Conclusions and RelevanceResults of this diagnostic study suggest that the RISAS procedure was the most feasible and accurate less-invasive procedure for axillary staging after NAC in patients with cN+ breast cancer.

Published
2023

14. Trends in Distal Esophageal and Gastroesophageal Junction Cancer Care: The Dutch Nationwide Ivory Study

Author

MS CGO, Cancer, Externen Med. Onco, Kalff, Marianne C, Henegouwen, Mark I van Berge, Baas, Peter C, Bahadoer, Renu R, Belt, Eric J T, Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D, Dekker, Jan Willem T, van Det, Marc J, Drost, Manon, van Duijvendijk, Peter, Eshuis, Wietse J, van Esser, Stijn, Gaspersz, Marcia P, Görgec, Burak, Groenendijk, Richard P R, Hartgrink, Henk H, van der Harst, Erwin, Haveman, Jan Willem, Heisterkamp, Joos, van Hillegersberg, Richard, Kelder, Wendy, Kingma, B Feike, Koemans, Willem J, Kouwenhoven, Ewout A, Lagarde, Sjoerd M, Lecot, Frederik, van der Linden, Philip P, Luyer, Misha D P, Nieuwenhuijzen, Grard A P, Olthof, Pim B, van der Peet, Donald L, Pierie, Jean-Pierre E N, Pierik, E G J M Robert, Plat, Victor D, Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P, van Sandick, Johanna W, Scheer, Rene, Slootmans, Cettela A M, Sosef, Meindert N, Sosef, Odin V, de Steur, Wobbe O, Stockmann, Hein B A C, Stoop, Fanny J, Voeten, Daan M, Vugts, Guusje, Vijgen, Guy H E J, Weeda, Víola B, Wiezer, Marinus J, van Oijen, Martijn G H, Gisbertz, Suzanne S, MS CGO, Cancer, Externen Med. Onco, Kalff, Marianne C, Henegouwen, Mark I van Berge, Baas, Peter C, Bahadoer, Renu R, Belt, Eric J T, Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D, Dekker, Jan Willem T, van Det, Marc J, Drost, Manon, van Duijvendijk, Peter, Eshuis, Wietse J, van Esser, Stijn, Gaspersz, Marcia P, Görgec, Burak, Groenendijk, Richard P R, Hartgrink, Henk H, van der Harst, Erwin, Haveman, Jan Willem, Heisterkamp, Joos, van Hillegersberg, Richard, Kelder, Wendy, Kingma, B Feike, Koemans, Willem J, Kouwenhoven, Ewout A, Lagarde, Sjoerd M, Lecot, Frederik, van der Linden, Philip P, Luyer, Misha D P, Nieuwenhuijzen, Grard A P, Olthof, Pim B, van der Peet, Donald L, Pierie, Jean-Pierre E N, Pierik, E G J M Robert, Plat, Victor D, Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P, van Sandick, Johanna W, Scheer, Rene, Slootmans, Cettela A M, Sosef, Meindert N, Sosef, Odin V, de Steur, Wobbe O, Stockmann, Hein B A C, Stoop, Fanny J, Voeten, Daan M, Vugts, Guusje, Vijgen, Guy H E J, Weeda, Víola B, Wiezer, Marinus J, van Oijen, Martijn G H, and Gisbertz, Suzanne S

Published
2023

15. Erratum to “Practice variation in anastomotic leak after esophagectomy: Unravelling differences in failure to rescue” [Eur J Surg Oncol 49 (5) (May 2023) 974–982]

Author

Heisterkamp, Joos, Polat, Fatih, Schouten, Jeroen, Singh, Pritam, Slootmans, Cettela A.M., Ultee, Gijs, Gisbertz, Suzanne S., Eshuis, Wietse J., Kalff, Marianne C., Feenstra, Minke L., van der Peet, Donald L., Stam, Wessel T., Van Etten, Boudewijn, Poelmann, Floris, Vuurberg, Nienke, Willem van den Berg, Jan, Martijnse, Ingrid S., Matthijsen, Robert M., Luyer, Misha, Curvers, Wout, Nieuwenhuijzen, Tom, Taselaar, Annick E., Kouwenhoven, Ewout A., Lubbers, Merel, Sosef, Meindert, Lecot, Frederik, Geraedts, Tessa C.M., van den Wildenberg, Frits, Kelder, Wendy, Baas, Peter C., de Haas, Job W.A., Hartgrink, Henk H., Bahadoer, Renu R., van Sandick, Johanna W., Hartemink, Koen J., Veenhof, Xander, Stockmann, Hein, Gorgec, Burak, Weeder, Pepijn, Wiezer, Marinus J., Genders, Charlotte M.S., Belt, Eric, Blomberg, Bjorn, van Duijvendijk, Peter, Claassen, Linda, Reetz, David, Steenvoorde, Pascal, Mastboom, Walter, Klein Ganseij, Henk Jan, van Dalsen, Annette D., Joldersma, Annalie, Zwakman, Marije, Groenendijk, Richard P.R., Montazeri, Mahsa, Mercer, Stuart, Knight, Benjamin, van Boxel, Gijs, McGregor, Richard J., Skipworth, Richard J.E., Frattini, Cristina, Bradley, Alice, Nilsson, Magnus, Hayami, Masaru, Huang, Biying, Bundred, James, Evans, Richard, Grimminger, Peter P., van der Sluis, Pieter C., Eren, Uzun, Saunders, John, Theophilidou, Elena, Khanzada, Zubair, Elliott, Jessie A., Ponten, Jeroen, King, Sinead, Reynolds, John V., Sgromo, Bruno, Akbari, Khalid, Shalaby, Samar, Gutschow, Christian A., Schmidt, Henner, Vetter, Diana, Moorthy, Krishna, Ibrahim, Mohamed A.H., Christodoulidis, Grigorious, Räsänen, Jari V., Kauppi, Juha, Söderström, Henna, Koshy, Renol, Manatakis, Dimitrios K., Korkolis, Dimitrios P., Balalis, Dimitrios, Rompu, Aliki, Alkhaffaf, Bilal, Alasmar, Mohamed, Arebi, Moaad, Piessen, Guillaume, Nuytens, Frederiek, Degisors, Sebastien, Ahmed, Ahmed, Boddy, Alex, Gandhi, Suraj, Fashina, Oluwatomini, Van Daele, Elke, Pattyn, Piet, Robb, William B., Arumugasamy, Mayilone, Al Azzawi, Mohammed, Whooley, Jack, Colak, Elif, Aybar, Engin, Sari, Ahmet C., Uyanik, Mustafa S., Ciftci, Ahmet B., Sayyed, Raza, Ayub, Bushra, Murtaza, Ghulam, Saeed, Aniqa, Ramesh, Priyanka, Charalabopoulos, Alexandros, Liakakos, Theodore, Schizas, Dimitrios, Baili, Efstratia, Kapelouzou, Alkistis, Valmasoni, Michele, Pierobon, Elisa Sefora, Capovilla, Giovanni, Merigliano, Stefano, Constantinoiu, Silviu, Birla, Rodica, Achim, Florin, Rosianu, Cristian Gelu, Hoara, Petre, Castro, Raúl Guevara, Salcedo, Andrés Felipe, Negoi, Ionut, Negoita, Valentina M., Ciubotaru, Cezar, Stoica, Bogdan, Hostiuc, Sorin, Colucci, Nicola, Mönig, Stefan P., Wassmer, Charles-Henri, Meyer, Jeremy, Takeda, Flavio Roberto, Aissar Sallum, Rubens Antonio, Ribeiro, Ulysses, Cecconello, Ivan, Toledo, Enrique, Trugeda, Maria Soledad, Fernández, María José, Gil, Carolina, Castanedo, Sonia, Isik, Arda, Kurnaz, Eray, Videira, José Flávio, Peyroteo, Mariana, Canotilho, Rita, Weindelmayer, Jacopo, Giacopuzzi, Simone, De Pasqual, Carlo Alberto, Bruna, Marcos, Mingol, Fernando, Vaque, Javier, Pérez, Carla, Phillips, Alexander W., Chmelo, Jakub, Brown, Joshua, Han, Laura E., Gossage, James A., Davies, Andrew R., Baker, Cara R., Kelly, Mark, Saad, Mohamed, Bernardi, Daniele, Bonavina, Luigi, Asti, Emanuele, Riva, Carlo, Scaramuzzo, Rosa, Elhadi, Muhammed, Ahmed, Hazem Abdelkarem, Elhadi, Ahmed, Elnagar, Faruk Ali, Msherghi, Ahmed A.A., Wills, Vanessa, Campbell, Cassidy, Cerdeira, Marisol Perez, Whiting, Scott, Merrett, Neil, Das, Amitabha, Apostolou, Christos, Lorenzo, Aldenb, Sousa, Fabiana, Barbosa, José Adelino, Devezas, Vítor, Barbosa, Elisabete, Fernandes, Cristina, Smith, Garett, Li, Edward Y., Bhimani, Nazim, Chan, Priscilla, Kotecha, Krishna, Hii, Michael W., Ward, Salena M., Johnson, MaryAnn, Read, Matthew, Chong, Lynn, Hollands, Michael J., Allaway, Matthew, Richardson, Arthur, Johnston, Emma, Chen, Andy Z.L., Kanhere, Harsh, Prasad, Shalvin, McQuillan, Patrick, Surman, Tim, Trochsler, MarkusI., Schofield, W.A., Ahmed, Syeda Khadijah, Reid, Jessica L., Harris, Mark C., Gananadha, Sivakumar, Farrant, Jessica, Rodrigues, Nicole, Fergusson, James, Hindmarsh, Andrew, Afzal, Zeeshan, Safranek, Peter, Sujendran, Vijay, Rooney, Siobhan, Loureiro, Carlos, Fernández, Saioa Leturio, Díez del Val, Ismael, Jaunoo, Shameen, Kennedy, Lauren, Hussain, Ahmed, Theodorou, Dimitrios, Triantafyllou, Tania, Theodoropoulos, Charalampos, Palyvou, Theodora, Ben Taher, Fatima Abdullah, Ekheel, Mustafa, Ubels, Sander, Matthée, Eric, Verstegen, Moniek, Klarenbeek, Bastiaan, Bouwense, Stefan, van Berge Henegouwen, Mark I., Daams, Freek, Dekker, Jan Willem T., van Det, Marc J., van Esser, Stijn, Griffiths, Ewen A., Haveman, Jan Willem, Nieuwenhuijzen, Grard, Siersema, Peter D., Wijnhoven, Bas, Hannink, Gerjon, van Workum, Frans, and Rosman, Camiel

Published
2023
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16. Practice variation in anastomotic leak after esophagectomy: Unravelling differences in failure to rescue

Author

Ubels, Sander, primary, Matthée, Eric, additional, Verstegen, Moniek, additional, Klarenbeek, Bastiaan, additional, Bouwense, Stefan, additional, van Berge Henegouwen, Mark I., additional, Daams, Freek, additional, Dekker, Jan Willem T., additional, van Det, Marc J., additional, van Esser, Stijn, additional, Griffiths, Ewen A., additional, Haveman, Jan Willem, additional, Nieuwenhuijzen, Grard, additional, Siersema, Peter D., additional, Wijnhoven, Bas, additional, Hannink, Gerjon, additional, van Workum, Frans, additional, Rosman, Camiel, additional, Heisterkamp, Joos, additional, Polat, Fatih, additional, Schouten, Jeroen, additional, Singh, Pritam, additional, Slootmans, Cettela A.M., additional, Ultee, Gijs, additional, Gisbertz, Suzanne S., additional, Eshuis, Wietse J., additional, Kalff, Marianne C., additional, Feenstra, Minke L., additional, van der Peet, Donald L., additional, Stam, Wessel T., additional, Van Etten, Boudewijn, additional, Poelmann, Floris, additional, Vuurberg, Nienke, additional, Willem van den Berg, Jan, additional, Martijnse, Ingrid S., additional, Matthijsen, Robert M., additional, Luyer, Misha, additional, Curvers, Wout, additional, Nieuwenhuijzen, Tom, additional, Taselaar, Annick E., additional, Kouwenhoven, Ewout A., additional, Lubbers, Merel, additional, Sosef, Meindert, additional, Lecot, Frederik, additional, Geraedts, Tessa C.M., additional, van den Wildenberg, Frits, additional, Kelder, Wendy, additional, Baas, Peter C., additional, de Haas, Job W.A., additional, Hartgrink, Henk H., additional, Bahadoer, Renu R., additional, van Sandick, Johanna W., additional, Hartemink, Koen J., additional, Veenhof, Xander, additional, Stockmann, Hein, additional, Gorgec, Burak, additional, Weeder, Pepijn, additional, Wiezer, Marinus J., additional, Genders, Charlotte M.S., additional, Belt, Eric, additional, Blomberg, Bjorn, additional, van Duijvendijk, Peter, additional, Claassen, Linda, additional, Reetz, David, additional, Steenvoorde, Pascal, additional, Mastboom, Walter, additional, Klein Ganseij, Henk Jan, additional, van Dalsen, Annette D., additional, Joldersma, Annalie, additional, Zwakman, Marije, additional, Groenendijk, Richard P.R., additional, Montazeri, Mahsa, additional, Mercer, Stuart, additional, Knight, Benjamin, additional, van Boxel, Gijs, additional, McGregor, Richard J., additional, Skipworth, Richard J.E., additional, Frattini, Cristina, additional, Bradley, Alice, additional, Nilsson, Magnus, additional, Hayami, Masaru, additional, Huang, Biying, additional, Bundred, James, additional, Evans, Richard, additional, Grimminger, Peter P., additional, van der Sluis, Pieter C., additional, Eren, Uzun, additional, Saunders, John, additional, Theophilidou, Elena, additional, Khanzada, Zubair, additional, Elliott, Jessie A., additional, Ponten, Jeroen, additional, King, Sinead, additional, Reynolds, John V., additional, Sgromo, Bruno, additional, Akbari, Khalid, additional, Shalaby, Samar, additional, Gutschow, Christian A., additional, Schmidt, Henner, additional, Vetter, Diana, additional, Moorthy, Krishna, additional, Ibrahim, Mohamed A.H., additional, Christodoulidis, Grigorious, additional, Räsänen, Jari V., additional, Kauppi, Juha, additional, Söderström, Henna, additional, Koshy, Renol, additional, Manatakis, Dimitrios K., additional, Korkolis, Dimitrios P., additional, Balalis, Dimitrios, additional, Rompu, Aliki, additional, Alkhaffaf, Bilal, additional, Alasmar, Mohamed, additional, Arebi, Moaad, additional, Piessen, Guillaume, additional, Nuytens, Frederiek, additional, Degisors, Sebastien, additional, Ahmed, Ahmed, additional, Boddy, Alex, additional, Gandhi, Suraj, additional, Fashina, Oluwatomini, additional, Van Daele, Elke, additional, Pattyn, Piet, additional, Robb, William B., additional, Arumugasamy, Mayilone, additional, Al Azzawi, Mohammed, additional, Whooley, Jack, additional, Colak, Elif, additional, Aybar, Engin, additional, Sari, Ahmet C., additional, Uyanik, Mustafa S., additional, Ciftci, Ahmet B., additional, Sayyed, Raza, additional, Ayub, Bushra, additional, Murtaza, Ghulam, additional, Saeed, Aniqa, additional, Ramesh, Priyanka, additional, Charalabopoulos, Alexandros, additional, Liakakos, Theodore, additional, Schizas, Dimitrios, additional, Baili, Efstratia, additional, Kapelouzou, Alkistis, additional, Valmasoni, Michele, additional, Pierobon, Elisa Sefora, additional, Capovilla, Giovanni, additional, Merigliano, Stefano, additional, Constantinoiu, Silviu, additional, Birla, Rodica, additional, Achim, Florin, additional, Rosianu, Cristian Gelu, additional, Hoara, Petre, additional, Castro, Raúl Guevara, additional, Salcedo, Andrés Felipe, additional, Negoi, Ionut, additional, Negoita, Valentina M., additional, Ciubotaru, Cezar, additional, Stoica, Bogdan, additional, Hostiuc, Sorin, additional, Colucci, Nicola, additional, Mönig, Stefan P., additional, Wassmer, Charles-Henri, additional, Meyer, Jeremy, additional, Takeda, Flavio Roberto, additional, Aissar Sallum, Rubens Antonio, additional, Ribeiro, Ulysses, additional, Cecconello, Ivan, additional, Toledo, Enrique, additional, Trugeda, Maria Soledad, additional, Fernández, María José, additional, Gil, Carolina, additional, Castanedo, Sonia, additional, Isik, Arda, additional, Kurnaz, Eray, additional, Videira, José Flávio, additional, Peyroteo, Mariana, additional, Canotilho, Rita, additional, Weindelmayer, Jacopo, additional, Giacopuzzi, Simone, additional, De Pasqual, Carlo Alberto, additional, Bruna, Marcos, additional, Mingol, Fernando, additional, Vaque, Javier, additional, Pérez, Carla, additional, Phillips, Alexander W., additional, Chmelo, Jakub, additional, Brown, Joshua, additional, Han, Laura E., additional, Gossage, James A., additional, Davies, Andrew R., additional, Baker, Cara R., additional, Kelly, Mark, additional, Saad, Mohamed, additional, Bernardi, Daniele, additional, Bonavina, Luigi, additional, Asti, Emanuele, additional, Riva, Carlo, additional, Scaramuzzo, Rosa, additional, Elhadi, Muhammed, additional, Ahmed, Hazem Abdelkarem, additional, Elhadi, Ahmed, additional, Elnagar, Faruk Ali, additional, Msherghi, Ahmed A.A., additional, Wills, Vanessa, additional, Campbell, Cassidy, additional, Cerdeira, Marisol Perez, additional, Whiting, Scott, additional, Merrett, Neil, additional, Das, Amitabha, additional, Apostolou, Christos, additional, Lorenzo, Aldenb, additional, Sousa, Fabiana, additional, Barbosa, José Adelino, additional, Devezas, Vítor, additional, Barbosa, Elisabete, additional, Fernandes, Cristina, additional, Smith, Garett, additional, Li, Edward Y., additional, Bhimani, Nazim, additional, Chan, Priscilla, additional, Kotecha, Krishna, additional, Hii, Michael W., additional, Ward, Salena M., additional, Johnson, MaryAnn, additional, Read, Matthew, additional, Chong, Lynn, additional, Hollands, Michael J., additional, Allaway, Matthew, additional, Richardson, Arthur, additional, Johnston, Emma, additional, Chen, Andy Z.L., additional, Kanhere, Harsh, additional, Prasad, Shalvin, additional, McQuillan, Patrick, additional, Surman, Tim, additional, Trochsler, MarkusI., additional, Schofield, W.A., additional, Ahmed, Syeda Khadijah, additional, Reid, Jessica L., additional, Harris, Mark C., additional, Gananadha, Sivakumar, additional, Farrant, Jessica, additional, Rodrigues, Nicole, additional, Fergusson, James, additional, Hindmarsh, Andrew, additional, Afzal, Zeeshan, additional, Safranek, Peter, additional, Sujendran, Vijay, additional, Rooney, Siobhan, additional, Loureiro, Carlos, additional, Fernández, Saioa Leturio, additional, Díez del Val, Ismael, additional, Jaunoo, Shameen, additional, Kennedy, Lauren, additional, Hussain, Ahmed, additional, Theodorou, Dimitrios, additional, Triantafyllou, Tania, additional, Theodoropoulos, Charalampos, additional, Palyvou, Theodora, additional, Ben Taher, Fatima Abdullah, additional, and Ekheel, Mustafa, additional

Published
2023
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18. Diagnostic Accuracy of Radioactive Iodine Seed Placement in the Axilla With Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Node-Positive Breast Cancer

Author

Simons, Janine M., primary, van Nijnatten, Thiemo J. A., additional, van der Pol, Carmen C., additional, van Diest, Paul J., additional, Jager, Agnes, additional, van Klaveren, David, additional, Kam, Boen L. R., additional, Lobbes, Marc B. I., additional, de Boer, Maaike, additional, Verhoef, Cees, additional, Sars, Paul R. A., additional, Heijmans, Harald J., additional, van Haaren, Els R. M., additional, Vles, Wouter J., additional, Contant, Caroline M. E., additional, Menke-Pluijmers, Marian B. E., additional, Smit, Léonie H. M., additional, Kelder, Wendy, additional, Boskamp, Marike, additional, Koppert, Linetta B., additional, Luiten, Ernest J. T., additional, and Smidt, Marjolein L., additional

Published
2022
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19. Patient-derived parathyroid organoids as a tracer and drug-screening application model

Author

Noltes, Milou E., primary, Sondorp, Luc H.J., additional, Kracht, Laura, additional, Antunes, Inês F., additional, Wardenaar, René, additional, Kelder, Wendy, additional, Kemper, Annelies, additional, Szymanski, Wiktor, additional, Zandee, Wouter T., additional, Jansen, Liesbeth, additional, Brouwers, Adrienne H., additional, Coppes, Robert P., additional, and Kruijff, Schelto, additional

Published
2022
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20. 186. RECURRENT DISEASE AFTER ESOPHAGEAL CANCER SURGERY; A SUBSTUDY OF THE DUTCH NATIONWIDE IVORY STUDY

Author

Henckens, Sofie, primary, Kalff, Marianne, additional, Voeten, Daan, additional, Heineman, David, additional, Hulshof, Maarten, additional, van Laarhoven, Hanneke, additional, Eshuis, Wietse, additional, Baas, Peter, additional, Bahadoer, Renu, additional, Belt, Eric, additional, Brattinga, Baukje, additional, Claassen, Linda, additional, Cosovic, Admira, additional, Crull, David, additional, Daams, Freek, additional, van Dalsen, Annette, additional, Dekker, Jan Willem, additional, van Det, Marc, additional, Drost, Manon, additional, van Duijvendijk, Peter, additional, van Esser, Stijn, additional, Gaspersz, Marcia, additional, Görgec, Burak, additional, Groenendijk, Richard, additional, Hartgrink, Henk, additional, van der Harst, Erwin, additional, Haveman, Jan Willem, additional, Heisterkamp, Joos, additional, van Hillegersberg, Richard, additional, Kelder, Wendy, additional, Kingma, Feike, additional, Koemans, Willem, additional, Kouwenhoven, Ewout, additional, Lagarde, Sjoerd, additional, Lecot, Frederik, additional, van der Linden, Philip, additional, Luyer, Misha, additional, Nieuwenhuijzen, Grard, additional, Olthof, Pim, additional, van der Peet, Donald, additional, Pierie, Jean-Pierre, additional, Pierik, Robert, additional, Plat, Victor, additional, Polat, Fatih, additional, Rosman, Camiel, additional, Ruurda, Jelle, additional, van Sandick, Johanna, additional, Scheer, Rene, additional, Slootmans, Cettela, additional, Sosef, Meindert, additional, Sosef, Odin, additional, de Steur, Wobbe, additional, Stockmann, Hein, additional, Stoop, Fanny, additional, Vugts, Guusje, additional, Vijgen, Guy, additional, Weeda, Viola, additional, Wiezer, Marinus, additional, van Ooijen, Martijn, additional, van Berge Henegouwen, Mark, additional, and Gisbertz, Suzanne, additional

Published
2022
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23. Diagnostic Accuracy of Radioactive Iodine Seed Placement in the Axilla With Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Node-Positive Breast Cancer

Author

Simons, Janine M, van Nijnatten, Thiemo J A, van der Pol, Carmen C, van Diest, Paul J, Jager, Agnes, van Klaveren, David, Kam, Boen L R, Lobbes, Marc B I, de Boer, Maaike, Verhoef, Cees, Sars, Paul R A, Heijmans, Harald J, van Haaren, Els R M, Vles, Wouter J, Contant, Caroline M E, Menke-Pluijmers, Marian B E, Smit, Léonie H M, Kelder, Wendy, Boskamp, Marike, Koppert, Linetta B, Luiten, Ernest J T, Smidt, Marjolein L, Simons, Janine M, van Nijnatten, Thiemo J A, van der Pol, Carmen C, van Diest, Paul J, Jager, Agnes, van Klaveren, David, Kam, Boen L R, Lobbes, Marc B I, de Boer, Maaike, Verhoef, Cees, Sars, Paul R A, Heijmans, Harald J, van Haaren, Els R M, Vles, Wouter J, Contant, Caroline M E, Menke-Pluijmers, Marian B E, Smit, Léonie H M, Kelder, Wendy, Boskamp, Marike, Koppert, Linetta B, Luiten, Ernest J T, and Smidt, Marjolein L

Abstract

Importance: Several less-invasive staging procedures have been proposed to replace axillary lymph node dissection (ALND) after neoadjuvant chemotherapy (NAC) in patients with initially clinically node-positive (cN+) breast cancer, but these procedures may fail to detect residual disease. Owing to the lack of high-level evidence, it is not yet clear which procedure is most optimal to replace ALND.Objective: To determine the diagnostic accuracy of radioactive iodine seed placement in the axilla with sentinel lymph node biopsy (RISAS), a targeted axillary dissection procedure.Design, Setting, and Participants: This was a prospective, multicenter, noninferiority, diagnostic accuracy trial conducted from March 1, 2017, to December 31, 2019. Patients were included within 14 institutions (general, teaching, and academic) throughout the Netherlands. Patients with breast cancer clinical tumor categories 1 through 4 (cT1-4; tumor diameter <2 cm and up to >5 cm or extension to the chest wall or skin) and pathologically proven positive axillary lymph nodes (ie, clinical node categories cN1, metastases to movable ipsilateral level I and/or level II axillary nodes; cN2, metastases to fixed or matted ipsilateral level I and/or level II axillary nodes; cN3b, metastases to ipsilateral level I and/or level II axillary nodes with metastases to internal mammary nodes) who were treated with NAC were eligible for inclusion. Data were analyzed from July 2020 to December 2021.Intervention: Pre-NAC, the marking of a pathologically confirmed positive axillary lymph node with radioactive iodine seed (MARI) procedure, was performed and after NAC, sentinel lymph node biopsy (SLNB) combined with excision of the marked lymph node (ie, RISAS procedure) was performed, followed by ALND.Main Outcomes and Measures: The identification rate, false-negative rate (FNR), and negative predictive value (NPV) were calculated for all 3 procedures: RISAS, SLNB, and MARI. The

Published
2022

24. Diagnostic Accuracy of Radioactive Iodine Seed Placement in the Axilla With Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Node-Positive Breast Cancer

Author

MS CGO, Pathologie, Cancer, Simons, Janine M, van Nijnatten, Thiemo J A, van der Pol, Carmen C, van Diest, Paul J, Jager, Agnes, van Klaveren, David, Kam, Boen L R, Lobbes, Marc B I, de Boer, Maaike, Verhoef, Cees, Sars, Paul R A, Heijmans, Harald J, van Haaren, Els R M, Vles, Wouter J, Contant, Caroline M E, Menke-Pluijmers, Marian B E, Smit, Léonie H M, Kelder, Wendy, Boskamp, Marike, Koppert, Linetta B, Luiten, Ernest J T, Smidt, Marjolein L, MS CGO, Pathologie, Cancer, Simons, Janine M, van Nijnatten, Thiemo J A, van der Pol, Carmen C, van Diest, Paul J, Jager, Agnes, van Klaveren, David, Kam, Boen L R, Lobbes, Marc B I, de Boer, Maaike, Verhoef, Cees, Sars, Paul R A, Heijmans, Harald J, van Haaren, Els R M, Vles, Wouter J, Contant, Caroline M E, Menke-Pluijmers, Marian B E, Smit, Léonie H M, Kelder, Wendy, Boskamp, Marike, Koppert, Linetta B, Luiten, Ernest J T, and Smidt, Marjolein L

Published
2022

25. Recurrent Disease after Esophageal Cancer Surgery: A Substudy of The Dutch Nationwide Ivory Study

Author

MS CGO, Cancer, Heelkunde Opleiding, Externen Med. Onco, Kalff, Marianne C, Henckens, Sofie P G, Voeten, Daan M, Heineman, David J, Hulshof, Maarten C C M, van Laarhoven, Hanneke W M, Eshuis, Wietse J, Baas, Peter C, Bahadoer, Renu R, Belt, Eric J T, Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D, Dekker, Jan Willem T, van Det, Marc J, Drost, Manon, Duijvendijk, Peter van, Esser, Stijn van, Gaspersz, Marcia P, Görgec, Burak, Groenendijk, Richard P R, Hartgrink, Henk H, Harst, Erwin van der, Haveman, Jan Willem, Heisterkamp, Joos, Hillegersberg, Richard van, Kelder, Wendy, Kingma, B Feike, Koemans, Willem J, Kouwenhoven, Ewout A, Lagarde, Sjoerd M, Lecot, Frederik, van der Linden, Philip P, Luyer, Misha D P, Nieuwenhuijzen, Grard A P, Olthof, Pim B, van der Peet, Donald L, Pierie, Jean-Pierre En, Pierik, E G J M Robert, Plat, Victor D, Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P, van Sandick, Johanna W, Scheer, Rene, Slootmans, Cettela AM, Sosef, Meindert N, Sosef, Odin V, de Steur, Wobbe O, Stockmann, Hein B A C, Stoop, Fanny J, Vugts, Guusje, Vijgen, Guy H E J, Weeda, Víola B, Wiezer, Marinus J, van Oijen, Martijn G H, van Berge Henegouwen, Mark I, Gisbertz, Suzanne S, MS CGO, Cancer, Heelkunde Opleiding, Externen Med. Onco, Kalff, Marianne C, Henckens, Sofie P G, Voeten, Daan M, Heineman, David J, Hulshof, Maarten C C M, van Laarhoven, Hanneke W M, Eshuis, Wietse J, Baas, Peter C, Bahadoer, Renu R, Belt, Eric J T, Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D, Dekker, Jan Willem T, van Det, Marc J, Drost, Manon, Duijvendijk, Peter van, Esser, Stijn van, Gaspersz, Marcia P, Görgec, Burak, Groenendijk, Richard P R, Hartgrink, Henk H, Harst, Erwin van der, Haveman, Jan Willem, Heisterkamp, Joos, Hillegersberg, Richard van, Kelder, Wendy, Kingma, B Feike, Koemans, Willem J, Kouwenhoven, Ewout A, Lagarde, Sjoerd M, Lecot, Frederik, van der Linden, Philip P, Luyer, Misha D P, Nieuwenhuijzen, Grard A P, Olthof, Pim B, van der Peet, Donald L, Pierie, Jean-Pierre En, Pierik, E G J M Robert, Plat, Victor D, Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P, van Sandick, Johanna W, Scheer, Rene, Slootmans, Cettela AM, Sosef, Meindert N, Sosef, Odin V, de Steur, Wobbe O, Stockmann, Hein B A C, Stoop, Fanny J, Vugts, Guusje, Vijgen, Guy H E J, Weeda, Víola B, Wiezer, Marinus J, van Oijen, Martijn G H, van Berge Henegouwen, Mark I, and Gisbertz, Suzanne S

Published
2022

27. Patient-derived parathyroid organoids as tracer and drug-screening application model

Author

Noltes, Milou E., primary, Sondorp, Luc H.J., additional, Kracht, Laura, additional, Antunes, Inês F., additional, Wardenaar, René, additional, Kelder, Wendy, additional, Kemper, Annelies, additional, Szymanski, Wiktor, additional, Zandee, Wouter T., additional, Jansen, Liesbeth, additional, Brouwers, Adrienne H., additional, Coppes, Robert P., additional, and Kruijff, Schelto, additional

Published
2022
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32. Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results

Author

van Dam, Gooitzen M., Themelis, George, Crane, Lucia M.A., Harlaar, Niels J., Pleijhuis, Rick G., Kelder, Wendy, Sarantopoulos, Athanasios, de Jong, Johannes S., Arts, Henriette J.G., van der Zee, Ate G.J., Bart, Joost, Low, Philip S., and Ntziachristos, Vasilis

Subjects
Chemotherapy -- Health aspects -- Patient outcomes -- Research, Cancer -- Chemotherapy, Cell receptors -- Physiological aspects -- Research, Ovarian cancer -- Care and treatment -- Diagnosis -- Genetic aspects -- Patient outcomes -- Research, Biological sciences, Health
Abstract

The prognosis in advanced-stage ovarian cancer remains poor. Tumor-specific intraoperative fluorescence imaging may improve staging and debulking efforts in cytoreductive surgery and thereby improve prognosis. The overexpression of folate receptor-α (FR-α) in 90-95% of epithelial ovarian cancers prompted the investigation of intraoperative tumor-specific fluorescence imaging in ovarian cancer surgery using an FR-α-targeted fluorescent agent. In patients with ovarian cancer, intraoperative tumor-specific fluorescence imaging with an FR-α-targeted fluorescent agent showcased the potential applications in patients with ovarian cancer for improved intraoperative staging and more radical cytoreductive surgery., Of all gynecologic malignancies, epithelial ovarian cancer (EOC) is the most frequent cause of death, both in the United States (1) and in Europe (2). The relative absence of a [...]

Published
2011
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33. Abstract GS1-10: Radioactive Iodine Seed placement in the Axilla with Sentinel lymph node biopsy after neoadjuvant chemotherapy in breast cancer: Results of the prospective multicenter RISAS trial

Author

Simons, Janine, primary, JA v Nijnatten, Thiemo, additional, Koppert, Linetta B, additional, van der Pol, Carmen C, additional, v Diest, Paul J, additional, Jager, Agnes, additional, v Klaveren, David, additional, Kam, Boen LR, additional, Lobbes, Marc BI, additional, de Boer, Maaike, additional, Verhoef, Cees, additional, Sars, Paul RA, additional, Heijmans, Harold J, additional, van Haaren, Els RM, additional, Vles, Wouter J, additional, Contant, Caroline ME, additional, Menke, Marian BE, additional, Smit, Leonie HM, additional, Kelder, Wendy, additional, Boskamp, Marike, additional, Mares-Engelberts, Ingeborg, additional, Luiten, Ernest JT, additional, and Smidt, Marjolein L, additional

Published
2021
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39. Validation and update of a lymph node metastasis prediction model for breast cancer

Author

Qiu, Si-Qi, primary, Aarnink, Merel, additional, van Maaren, Marissa C., additional, Dorrius, Monique D., additional, Bhattacharya, Arkajyoti, additional, Veltman, Jeroen, additional, Klazen, Caroline A.H., additional, Korte, Jan H., additional, Estourgie, Susanne H., additional, Ott, Pieter, additional, Kelder, Wendy, additional, Zeng, Huan-Cheng, additional, Koffijberg, Hendrik, additional, Zhang, Guo-Jun, additional, van Dam, Gooitzen M., additional, and Siesling, Sabine, additional

Published
2018
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40. Lymph node staging in colon cancer

Author

Kelder, Wendy, Kelder, Wendy, Kelder, Wendy, and Kelder, Wendy

Abstract

The prognosis of patients with colon cancer is generally related to the degree of invasion of the tumor through the bowel wall and the presence or absence of lymph node involvement and distant metastases. Adjuvant chemotherapy is given to patients with lymph node metastases (stage II) and some patients without nodal metastases but with certain unfavorable tumour characteristics. Despite the good prognosis of patients without lymph node metastases (stage II colon cancer), 20-30% of these patients will develop recurrent disease, even after apparently curative resection.1 In this thesis an attempt was made to improve current staging and to identify those patients in the current stage II group who have an increased risk of developing recurrent disease in the future and who might benefit from adjuvant treatment. This was based on the assumption that some patients in the stage II group actually belong to the stage III groep (patients with lymph node metastases). In other words, with the current techniques of lymph node analysis some nodal metastases may be missed, leading to a false node-negative classification in some stage II patients. There are two explanations for this nodal ‘understaging’. It is possible that not enough nodes are identified from the colon specimen, leaving some positive nodes unidentified. In addition, it might be that the identified nodes are insufficiently examined, thereby missing the smaller metastases. We performed 2 studies on the subject of the number of examined nodes. First the quality of lymph node sampling in colon carcinoma in the Northern part of the Netherlands was studied. It appeared that T-stage, tumor localization and patient age were related to the number of nodes examined. In 70% of the patients less than the recommanded 12 nodes were examined. A higher number of examined nodes was associated with an increase in node-positivity. The survival benefit with more examined lymph nodes in N0 patients can be explained by stage migration.

Published
2008

41. Validation and update of a lymph node metastasis prediction model for breast cancer.

Author

van Dam, Gooitzen M., Qiu, Si-Qi, Estourgie, Susanne H., Ott, Pieter, Kelder, Wendy, Zhang, Guo-Jun, Zeng, Huan-Cheng, Aarnink, Merel, Koffijberg, Hendrik, Siesling, Sabine, van Maaren, Marissa C., Dorrius, Monique D., Bhattacharya, Arkajyoti, Veltman, Jeroen, Klazen, Caroline A.H., and Korte, Jan H.

Subjects
BREAST cancer, METASTASIS, PREDICTION models, SURGERY, LYMPH nodes
Abstract

Purpose This study aimed to validate and update a model for predicting the risk of axillary lymph node (ALN) metastasis for assisting clinical decision-making. Methods We included breast cancer patients diagnosed at six Dutch hospitals between 2011 and 2015 to validate the original model which includes six variables: clinical tumor size, tumor grade, estrogen receptor status, lymph node longest axis, cortical thickness and hilum status as detected by ultrasonography. Subsequently, we updated the original model using generalized linear model (GLM) tree analysis and by adjusting its intercept and slope. The area under the receiver operator characteristic curve (AUC) and calibration curve were used to assess the original and updated models. Clinical usefulness of the model was evaluated by false-negative rates (FNRs) at different cut-off points for the predictive probability. Results Data from 1416 patients were analyzed. The AUC for the original model was 0.774. Patients were classified into four risk groups by GLM analysis, for which four updated models were created. The AUC for the updated models was 0.812. The calibration curves showed that the updated model predictions were better in agreement with actual observations than the original model predictions. FNRs of the updated models were lower than the preset 10% at all cut-off points when the predictive probability was less than 12.0%. Conclusions The original model showed good performance in the Dutch validation population. The updated models resulted in more accurate ALN metastasis prediction and could be useful preoperative tools in selecting low-risk patients for omission of axillary surgery. [ABSTRACT FROM AUTHOR]

Published
2018
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42. Prospective study of sentinel node biopsy for high-risk cutaneous squamous cell carcinoma of the head and neck

Author

Gore, Sinclair M., primary, Shaw, Douglas, additional, Martin, Richard C. W., additional, Kelder, Wendy, additional, Roth, Kathryn, additional, Uren, Roger, additional, Gao, Kan, additional, Davies, Sarah, additional, Ashford, Bruce G., additional, Ngo, Quan, additional, Shannon, Kerwin, additional, and Clark, Jonathan R., additional

Published
2015
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47. Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-? targeting: first in-human results.

Author

van Dam, Gooitzen M, Themelis, George, Crane, Lucia M A, Harlaar, Niels J, Pleijhuis, Rick G, Kelder, Wendy, Sarantopoulos, Athanasios, de Jong, Johannes S, Arts, Henriette J G, van der Zee, Ate G J, Bart, Joost, Low, Philip S, and Ntziachristos, Vasilis

Subjects
OVARIAN cancer, ONCOLOGIC surgery, PROGNOSIS, FLUORESCENCE spectroscopy, OPERATIVE ultrasonography
Abstract

The prognosis in advanced-stage ovarian cancer remains poor. Tumor-specific intraoperative fluorescence imaging may improve staging and debulking efforts in cytoreductive surgery and thereby improve prognosis. The overexpression of folate receptor-? (FR-?) in 90-95% of epithelial ovarian cancers prompted the investigation of intraoperative tumor-specific fluorescence imaging in ovarian cancer surgery using an FR-?-targeted fluorescent agent. In patients with ovarian cancer, intraoperative tumor-specific fluorescence imaging with an FR-?-targeted fluorescent agent showcased the potential applications in patients with ovarian cancer for improved intraoperative staging and more radical cytoreductive surgery. [ABSTRACT FROM AUTHOR]

Published
2011
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48. RT-PCR and immunohistochemical evaluation of sentinel lymph nodes after in vivo mapping with Patent Blue V in colon cancer patients.

Author

Kelder, Wendy, Van Den Berg, Anke, Van Der Leij, Judith, Bleeker, Wim, Tiebosch, Anton T. M. G., Grond, Joris K., Baas, Peter C., and Plukker, John TH.

Abstract

Objective. Lymph node status is the most important predictive factor in the treatment of colorectal cancer. As sentinel lymph node (SLN) biopsy might upstage stage II colon cancer, it could have therapeutic consequences in the future. We investigated the feasibility of in vivo SLN detection with Patent Blue V dye and evaluated nodal microstaging and ultrastaging using cytokeratin immunohistochemistry and reverse transcriptase-polymerase chain reaction (RT-PCR). Material and methods. In 30 consecutive patients operated on for colon cancer, subserosal injection with Patent Blue dye was used for SLN detection in four different hospitals under the supervision of one regional coordinator. In searching for occult micrometastases, each SLN was examined at three levels. In tumor-negative SLNs at routine hematoxylin-eosin (H&E) examination (pN0) we performed CK8/CK18 immunohistochemistry (IHC) and RT-PCR for carcinoembryonic antigen (CEA). Results. The procedure was successful in 29 out of 30 patients (97%). The SLN was negative in 18 patients detected by H&E and IHC. In 16 patients the non-SLN was also negative, leading to a negative predictive value of 89% and an accuracy of 93%. Upstaging occurred in 10 patients (33%) – 7 by IHC and 3 by RT-PCR. Aberrant lymphatic drainage was seen in 3 patients (10%). Conclusions. The SLN concept in colon carcinoma using Patent Blue V is feasible and accurate. It leads to upstaging of nodal status in 33% of patients when IHC and PCR techniques are combined. Therefore, the clinical value of SLN should be the subject of further studies. [ABSTRACT FROM AUTHOR]

Published
2006
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50. The Effect of a Temporary Stoma on Long-term Functional Outcomes Following Surgery for Rectal Cancer.

Author

Verkuijl SJ, Jonker JE, Furnée EJB, Kelder W, Hoff C, Hess DA, Wit F, Zijlstra RJ, Trzpis M, and Broens PMA

Subjects
Humans, Cross-Sectional Studies, Postoperative Complications epidemiology, Postoperative Complications etiology, Low Anterior Resection Syndrome, Ileostomy adverse effects, Colostomy, Constipation etiology, Retrospective Studies, Rectal Neoplasms surgery, Rectal Neoplasms etiology, Fecal Incontinence epidemiology, Fecal Incontinence etiology
Abstract

Background: Patients with rectal cancer may undergo surgical resection with or without a temporary stoma., Objective: This study primarily aimed to compare long-term functional outcomes between patients with and without a temporary stoma after surgery for rectal cancer. The secondary aim was to investigate the effect of time to stoma reversal on functional outcomes., Design: This was a multicenter, cross-sectional study., Settings: This study was conducted at 7 Dutch hospitals., Patients: Included were patients who had undergone rectal cancer surgery (2009-2015). Excluded were deceased patients, who were deceased, had a permanent stoma, or had intellectual disability., Main Outcome Measures: Functional outcomes were measured using the Rome IV criteria for constipation and fecal incontinence and the low anterior resection syndrome score., Results: Of 656 patients, 32% received a temporary ileostomy and 20% a temporary colostomy (86% response). Follow-up was at 56 (interquartile range, 38.5-79) months. Patients who had a temporary ileostomy experienced less constipation, more fecal incontinence, and more major low anterior resection syndrome than those without a temporary stoma. Patients who had a temporary colostomy experienced more major low anterior resection syndrome than those without a temporary stoma. A temporary ileostomy or colostomy was not associated with constipation or fecal incontinence after correction for confounding factors (eg, anastomotic height, anastomotic leakage, radiotherapy). Time to stoma reversal was not associated with constipation, fecal incontinence, or major low anterior resection syndrome., Limitations: Cross-sectional design., Conclusions: Although patients with a temporary ileostomy or colostomy have worse functional outcomes in the long term, it seems that the reason for creating a temporary stoma, rather than the stoma itself, underlies this phenomenon. Time to reversal of a temporary stoma does not influence functional outcomes. See Video Abstract ., El Efecto Del Estoma Temporal Sobre Los Resultados Funcionales a Largo Plazo Despus De La Ciruga Por Cncer De Recto: ANTECEDENTES:Los pacientes con cáncer de recto pueden someterse a resección quirúrgica con o sin un estoma temporal.OBJETIVO:El objetivo principal de este estudio fue comparar los resultados funcionales a largo plazo entre pacientes con y sin estoma temporal después de cirugía por cáncer de recto. El objetivo secundario fue investigar el efecto del tiempo transcurrido hasta la reversión del estoma sobre los resultados funcionales.DISEÑO:Este fue un estudio transversal multicéntrico.ESCENARIO:Este estudio se llevó a cabo en siete hospitales holandeses.PACIENTES:Se incluyeron pacientes sometidos a cirugía de cáncer de recto (2009-2015). Se excluyeron pacientes fallecidos, pacientes con estoma permanente o discapacidad intelectual.PRINCIPALES MEDIDAS DE RESULTADO:Los resultados funcionales se midieron utilizando los criterios de Roma IV para el estreñimiento y la incontinencia fecal y la puntuación del síndrome de resección anterior baja (LARS).RESULTADOS:De 656 pacientes, el 32% recibió una ileostomía temporal y el 20% una colostomía temporal (respuesta del 86%). El seguimiento fue de 56.0 (RIQ 38.5-79.0) meses. Los pacientes a los que se les realizó una ileostomía temporal experimentaron menos estreñimiento, más incontinencia fecal y más LARS mayor que los pacientes sin un estoma temporal. Los pacientes que tuvieron una colostomía temporal experimentaron más LARS mayor que los pacientes sin un estoma temporal. Una ileostomía o colostomía temporal no se asoció con estreñimiento o incontinencia fecal después de la corrección de factores de confusión (p. ej., altura anastomótica, fuga anastomótica, radioterapia). El tiempo hasta la reversión del estoma no se asoció con estreñimiento, incontinencia fecal o LARS mayor.LIMITACIONES:El presente estudio está limitado por su diseño transversal.CONCLUSIONES:Aunque los pacientes con una ileostomía o colostomía temporal tienen peores resultados funcionales a largo plazo, parece que la razón para crear un estoma temporal, más que el estoma en sí, se asocia a este fenómeno. El tiempo hasta la reversión de un estoma temporal no influye en los resultados funcionales. (Traducción-Dr. Jorge Silva Velazco )., (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Colon and Rectal Surgeons.)

Published
2024
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