1. Thyroid storm caused by a partial hydatidiform mole
- Author
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Niyati U. Chiniwala, Christopher P. Bruno, Paul D. Woolf, Sukhjinder Kaur, Kelli Yacono, and Harvey Spector
- Subjects
Adult ,endocrine system ,medicine.medical_specialty ,endocrine system diseases ,Endocrinology, Diabetes and Metabolism ,Thyroid Gland ,Chorionic Gonadotropin ,Hyperthyroidism ,Human chorionic gonadotropin ,Hyperemesis gravidarum ,Endocrinology ,Molar pregnancy ,Pregnancy ,Internal medicine ,medicine ,Thyroid storm ,Humans ,reproductive and urinary physiology ,Partial Hydatidiform Mole ,urogenital system ,business.industry ,Hydatidiform Mole ,medicine.disease ,Normal thyroid function ,Trophoblasts ,Pregnancy Complications ,Thyroxine ,Treatment Outcome ,Gestation ,Triiodothyronine ,Female ,Thyroid Crisis ,business ,hormones, hormone substitutes, and hormone antagonists - Abstract
Clinical thyrotoxicosis is rare in molar pregnancy and has yet to be reported in a patient with a partial mole. Human chorionic gonadotropin (hCG), which has thyrotropic activity, is believed to be responsible for hyperthyroidism of gestational trophoblastic activity and hyperemesis gravidarum. We report the first case of hyperthyroidism presenting as thyroid storm in a partial molar pregnancy. Normal thyroid function returned after the partial mole was evacuated, and the biochemical improvement correlated with declining hCG levels. This case highlights the importance of including partial mole in the differential of hCG-mediated hyperthyroidism.
- Published
- 2008