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Objective: This study aims to evaluate the application of 3D-printed individual vertebral prostheses for reconstructing the spine following thoracolumbar Total En-bloc Spondylectomy (TES) in patients with benign spinal tumors. The primary objectives include assessing the feasibility of 3D-printed prostheses in various reconstruction scenarios and determining their impact on spinal stability and neurological function in the short term. Methods: A retrospective analysis was conducted on four patients who underwent TES between 2019 and 2020. Patient data, including demographics, tumor characteristics, and surgical details, were collected. Customized 3D-printed vertebral prostheses were created based on computed tomography (CT) and magnetic resonance imaging (MRI) scans. Surgical procedures were performed, and clinical outcomes were assessed using the Visual Analog Scale (VAS) for pain and the Oswestry Disability Index (ODI) for functional status. Mechanical strength testing of the implants was conducted, and statistical analysis was performed using ANOVA (p<0.0001). Results: Preliminary results indicate that 3D-printed individual vertebral prostheses are suitable for anterior column reconstruction following TES. VAS and ODI scores showed significant improvements post-surgery, reflecting reduced pain and enhanced functional outcomes. Mechanical testing revealed the implants’ robustness, with no signs of deformation or failure even at maximum loads. Conclusions: The integration of 3D printing technology into spinal surgery holds promise for optimizing patientspecific reconstructions. Customized vertebral prostheses offer benefits such as improved surgical planning, reduced procedure duration, and minimized perioperative blood loss. While challenges, including the need for specialized software and limited long-term data, exist, this study underscores the potential of 3D-printed implants in enhancing patient outcomes. Further research with a larger patient cohort and longer follow-up periods is essential to confirm the effectiveness of personalized implants in spinal surgery [ABSTRACT FROM AUTHOR]

Objective: To present the results of IMSCT’s (Intramedullary Spinal Cord Tumor) surgery at the National Centre for Neurosurgery. Materials and methods: A 102 patients operated from July 2008 to December 2017. Among them, 7 cases of a continued growth, 1 – recurrence. The mean age was 41 (ranged 16-67y.o), 49 were men and 45 women. Routine MRI examination, McCormick (McC) and Klekamp–Samii (KS) scale assessment was performed pre and postoperatively. Preoperative functional status was good in 37% of patients, in 63% was poor. The follow up was from 3 months to 9 years (mean 4.6 years). Results: The improvement achieved in 66 (64.7%) with complete recovery in 8 patients (12%), no changes – 21 (20.5%), deterioration – 15 (14.7%). One patient had complete neurological recovery in a late post-op period. Neurological worsening was due to recurrence, continued growth and histology. In 10 cases we experienced mortality, 1 due to pulmonary artery thrombosis, 3 – continued tumor growth, 2 – concomitant disease, 4 with G = III and G = IV tumors (after combined treatment). There is a direct correlation between the preoperative neurological status and the expected postoperative outcome (p> 0.05). Conclusion: Along with the total resection of tumor and histological structure, the preoperative neurological status is one of the main determining factors of the expected result. [ABSTRACT FROM AUTHOR]