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343 results on '"Keshtgar, Mohammed"'

4. A Partially Supervised Bayesian Image Classification Model with Applications in Diagnosis of Sentinel Lymph Node Metastases in Breast Cancer

Author

Zhu, Ying, Fearn, Tom, Chicken, D. Wayne, Austwick, Martin R., Somasundaram, Santosh K., Mosse, Charles A., Clark, Benjamin, Bigio, Irving J., Keshtgar, Mohammed R. S., and Bown, Stephen G.

Subjects
Statistics - Applications
Abstract

A method has been developed for the analysis of images of sentinel lymph nodes generated by a spectral scanning device. The aim is to classify the nodes, excised during surgery for breast cancer, as normal or metastatic. The data from one node constitute spectra at 86 wavelengths for each pixel of a 20*20 grid. For the analysis, the spectra are reduced to scores on two factors, one derived externally from a linear discriminant analysis using spectra taken manually from known normal and metastatic tissue, and one derived from the node under investigation to capture variability orthogonal to the external factor. Then a three-group mixture model (normal, metastatic, non-nodal background) using multivariate t distributions is fitted to the scores, with external data being used to specify informative prior distributions for the parameters of the three distributions. A Markov random field prior imposes smoothness on the image generated by the model. Finally, the node is classified as metastatic if any one pixel in this smoothed image is classified as metastatic. The model parameters were tuned on a training set of nodes, and then the tuned model was tested on a separate validation set of nodes, achieving satisfactory sensitivity and specificity. The aim in developing the analysis was to allow flexibility in the way each node is modelled whilst still using external information. The Bayesian framework employed is ideal for this., Comment: 31 pages, 7 figures

Published
2017

5. A comparative study of breast surface reconstruction for aesthetic outcome assessment

Author

Lacher, Rene, Vasconcelos, Francisco, Bishop, David, Williams, Norman, Keshtgar, Mohammed, Hawkes, David, Hipwell, John, and Stoyanov, Danail

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

Breast cancer is the most prevalent cancer type in women, and while its survival rate is generally high the aesthetic outcome is an increasingly important factor when evaluating different treatment alternatives. 3D scanning and reconstruction techniques offer a flexible tool for building detailed and accurate 3D breast models that can be used both pre-operatively for surgical planning and post-operatively for aesthetic evaluation. This paper aims at comparing the accuracy of low-cost 3D scanning technologies with the significantly more expensive state-of-the-art 3D commercial scanners in the context of breast 3D reconstruction. We present results from 28 synthetic and clinical RGBD sequences, including 12 unique patients and an anthropomorphic phantom demonstrating the applicability of low-cost RGBD sensors to real clinical cases. Body deformation and homogeneous skin texture pose challenges to the studied reconstruction systems. Although these should be addressed appropriately if higher model quality is warranted, we observe that low-cost sensors are able to obtain valuable reconstructions comparable to the state-of-the-art within an error margin of 3 mm., Comment: This paper has been accepted to MICCAI2017

Published
2017

9. Electrochemotherapy for Breast Cancer—Results From the INSPECT Database

Author

Matthiessen, Louise Wichmann, Keshtgar, Mohammed, Curatolo, Pietro, Kunte, Christian, Grischke, Eva-Maria, Odili, Joy, Muir, Tobian, Mowatt, David, Clover, James P., Liew, Se Hwang, Dahlstroem, Karin, Newby, Jackie, Letulé, Valerie, Stauss, Eva, Humphreys, Alison, Banerjee, Shramana, Klein, Annette, Rotunno, Roberta, de Terlizzi, Francesca, and Gehl, Julie

Published
2018
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10. The value of 3D images in the aesthetic evaluation of breast cancer conservative treatment. Results from a prospective multicentric clinical trial

Author

Gouveia, Pedro, Keshtgar, Mohammed, Mosahebi, Ash, Bishop, David, Lacher, René, Liefers, Gerrit Jan, Molenkamp, Barbara, Van de Velde, Cornelius, Azevedo, Isabel, Canny, Rebecca, Christie, David, Evans, Andy, Fitzal, Florian, Graham, Peter, Hamdi, Moustapha, Joahensen, Jorgen, Laws, Siobban, Merck, Belén, Reece, Gregory, Sacchini, Virgilio, Vrancken, Marie-Jeanne, Wilkinson, Louise, Matthes, Gustavo Zucca, Cardoso, Maria João, Vrieling, Conny, Cardoso, Jaime S., Oliveira, Helder P., Williams, Norman R., and Dixon, J.M.

Published
2018
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11. A Comparative Study of Breast Surface Reconstruction for Aesthetic Outcome Assessment

Author

Lacher, René M., Vasconcelos, Francisco, Bishop, David C., Williams, Norman R., Keshtgar, Mohammed, Hawkes, David J., Hipwell, John H., Stoyanov, Danail, Hutchison, David, Editorial Board Member, Kanade, Takeo, Editorial Board Member, Kittler, Josef, Editorial Board Member, Kleinberg, Jon M., Editorial Board Member, Mattern, Friedemann, Editorial Board Member, Mitchell, John C., Editorial Board Member, Naor, Moni, Editorial Board Member, Pandu Rangan, C., Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Terzopoulos, Demetri, Editorial Board Member, Tygar, Doug, Editorial Board Member, Weikum, Gerhard, Series Editor, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Descoteaux, Maxime, editor, Maier-Hein, Lena, editor, Franz, Alfred, editor, Jannin, Pierre, editor, Collins, D. Louis, editor, and Duchesne, Simon, editor

Published
2017
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12. Combination of verteporfin-photodynamic therapy with 5-aza-2’-deoxycytidine enhances the anti-tumour immune response in triple negative breast cancer

Author

Banerjee, Shramana M., primary, Acedo, Pilar, additional, El Sheikh, Soha, additional, Harati, Rania, additional, Meecham, Amelia, additional, Williams, Norman R., additional, Gerard, Gareth, additional, Keshtgar, Mohammed R. S., additional, MacRobert, Alexander J., additional, and Hamoudi, Rifat, additional

Published
2023
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19. Case Reports

Author

Pigott, Katharine, Wenz, Frederik, Keshtgar, Mohammed, Eljamel, Sam, Polkowski, Wojciech P., Reis, Tina, Abo-Madyan, Yasser, Ehmann, Michael, Keshtgar, Mohammed, editor, Pigott, Katharine, editor, and Wenz, Frederik, editor

Published
2014
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21. Breast Conserving Surgery Outcome Prediction: A Patient-Specific, Integrated Multi-modal Imaging and Mechano-Biological Modelling Framework

Author

Eiben, Björn, Lacher, Rene, Vavourakis, Vasileios, Hipwell, John H., Stoyanov, Danail, Williams, Norman R., Sabczynski, Jörg, Bülow, Thomas, Kutra, Dominik, Meetz, Kirsten, Young, Stewart, Barschdorf, Hans, Oliveira, Hélder P., Cardoso, Jaime S., Monteiro, João P., Zolfagharnasab, Hooshiar, Sinkus, Ralph, Gouveia, Pedro, Liefers, Gerrit-Jan, Molenkamp, Barbara, van de Velde, Cornelis J. H., Hawkes, David J., Cardoso, Maria João, Keshtgar, Mohammed, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Tingberg, Anders, editor, Lång, Kristina, editor, and Timberg, Pontus, editor

Published
2016
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25. Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial

Author

Vaidya, Jayant S, Wenz, Frederik, Bulsara, Max, Tobias, Jeffrey S, Joseph, David J, Keshtgar, Mohammed, Flyger, Henrik L, Massarut, Samuele, Alvarado, Michael, Saunders, Christobel, Eiermann, Wolfgang, Metaxas, Marinos, Sperk, Elena, Sütterlin, Marc, Brown, Douglas, Esserman, Laura, Roncadin, Mario, Thompson, Alastair, Dewar, John A, Holtveg, Helle M R, Pigorsch, Steffi, Falzon, Mary, Harris, Eleanor, Matthews, April, Brew-Graves, Chris, Potyka, Ingrid, Corica, Tammy, Williams, Norman R, and Baum, Michael

Published
2014
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28. Tissue Screening after Breast Reduction

Author

Keshtgar, Mohammed, Treasure, Tom, Sugarman, Jeremy, Boase, Tessa, Jahromi, Alireza Hamidian, Davidson, Tim, Escobar, Paula, Mallucci, Patrick, Mosahebi, Afshin, and Baum, Michael

Published
2009

31. Breast Conserving Surgery Outcome Prediction: A Patient-Specific, Integrated Multi-modal Imaging and Mechano-Biological Modelling Framework

Author

Eiben, Björn, primary, Lacher, Rene, additional, Vavourakis, Vasileios, additional, Hipwell, John H., additional, Stoyanov, Danail, additional, Williams, Norman R., additional, Sabczynski, Jörg, additional, Bülow, Thomas, additional, Kutra, Dominik, additional, Meetz, Kirsten, additional, Young, Stewart, additional, Barschdorf, Hans, additional, Oliveira, Hélder P., additional, Cardoso, Jaime S., additional, Monteiro, João P., additional, Zolfagharnasab, Hooshiar, additional, Sinkus, Ralph, additional, Gouveia, Pedro, additional, Liefers, Gerrit-Jan, additional, Molenkamp, Barbara, additional, van de Velde, Cornelis J. H., additional, Hawkes, David J., additional, Cardoso, Maria João, additional, and Keshtgar, Mohammed, additional

Published
2016
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32. Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial

Author

Vaidya, Jayant S, Joseph, David J, Tobias, Jeffrey S, Bulsara, Max, Wenz, Frederik, Saunders, Christobel, Alvarado, Michael, Flyger, Henrik L, Massarut, Samuele, Eiermann, Wolfgang, Keshtgar, Mohammed, Dewar, John, Kraus-Tiefenbacher, Uta, Sütterlin, Marc, Esserman, Laura, Holtveg, Helle MR, Roncadin, Mario, Pigorsch, Steffi, Metaxas, Marinos, Falzon, Mary, Matthews, April, Corica, Tammy, Williams, Norman R, and Baum, Michael

Published
2010
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43. Case Reports

Author

Pigott, Katharine, primary, Wenz, Frederik, additional, Keshtgar, Mohammed, additional, Eljamel, Sam, additional, Polkowski, Wojciech P., additional, Reis, Tina, additional, Abo-Madyan, Yasser, additional, and Ehmann, Michael, additional

Published
2013
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47. Do religious/spiritual coping strategies affect illness adjustment in patients with cancer? A systematic review of the literature

Author

Thune-Boyle, Ingela C., Stygall, Jan A., Keshtgar, Mohammed R., and Newman, Stanton P.

Subjects
Cancer patients -- Care and treatment, Cancer patients -- Analysis, Oncology, Experimental -- Analysis, Cancer -- Care and treatment, Cancer -- Analysis, Cancer -- Research, Health, Social sciences
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.socscimed.2005.11.055 Byline: Ingela C. Thune-Boyle (a)(b), Jan A. Stygall (a)(b), Mohammed R. Keshtgar (c), Stanton P. Newman (a) Keywords: Religious coping; Cancer; Illness adjustment; Distress; Systematic review Abstract: The present paper systematically reviews studies examining the potential beneficial or harmful effects of religious/spiritual coping with cancer. Using religion and spirituality as resources in coping may be specifically prevalent in patients with cancer considering the potentially life-threatening nature of the illness. Religious/spiritual coping may also serve multiple functions in long-term adjustment to cancer such as maintaining self-esteem, providing a sense of meaning and purpose, giving emotional comfort and providing a sense of hope. Seventeen papers met the inclusion criteria of which seven found some evidence for the beneficial effect of religious coping, but one of these also found religious coping to be detrimental in a sub-sample of their population. A further three studies found religious coping to be harmful and seven found non-significant results. However, many studies suffered from serious methodological problems, especially in the manner in which religious coping was conceptualised and measured. The studies also failed to control for possible influential variables such as stage of illness and perceived social support. Due to this, any firm conclusions about the possible beneficial or harmful effects of religious coping with cancer is lacking. These problems are discussed and suggestions for future studies are made. Author Affiliation: (a) Centre for Behavioural & Social Sciences in Medicine, University College London, 48 Riding House St, London W1W 7EY, UK (b) Thames Valley University, UK (c) Dept of Surgery, University College London, UK

Published
2006

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