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34 results on '"Khabarov, S. V."'

1. Conceptual design of the Spin Physics Detector

Author

Abazov, V. M., Abramov, V., Afanasyev, L. G., Akhunzyanov, R. R., Akindinov, A. V., Akopov, N., Alekseev, I. G., Aleshko, A. M., Alexakhin, V. Yu., Alexeev, G. D., Alexeev, M., Amoroso, A., Anikin, I. V., Andreev, V. F., Anosov, V. A., Arbuzov, A. B., Azorskiy, N. I., Baldin, A. A., Balandina, V. V., Baldina, E. G., Barabanov, M. Yu., Barsov, S. G., Baskov, V. A., Beloborodov, A. N., Belov, I. N., Belova, A. P., Belyaev, A. V., Berdnikov, A. Ya., Berdnikov, Ya. A., Berezhnoy, A. V., Bleko, V. V., Bobkov, A. V., Bogoslovsky, D. N., Boguslavsky, I. N., Boltushkin, E. V., Boos, E. E., Burtsev, V. E., Chen, Lei, Chepurnov, A. S., Chiosso, M., Chumakov, A., Dalkarov, O. D., Datta, A., Demikhov, E. I., Denisenko, I. I., Denisov, O. Yu., Duginov, V. N., Dunin, V. B., Dygnarowicz, K., Efremov, A. V., El-Kholy, R., Eliseev, D. A., Enik, T. L., Fedin, O. L., Feofilov, G. A., Filatov, Yu. N., Finger, M., Frolov, V. N., Galinski, G., Galoyan, A. S., Trapaga, C. E Garsia, Gavrishchuk, O. P., Gerasimov, S. G., Glonti, L., Goloskokov, S. V., Golovanov, G. A., Golubev, A. A., M., Golubykh S., V., Goncharov P., O., Grafov N., Y., Gribkov D., Gribovsky, A. S., Gridin, A. O., Grinyov, B. V., Gritsay, K. I., Gromov, S. A., Gromov, V. A., Gurchin, Yu. V., Gusakov, Yu. V., Guskov, A. V., Guzman, F., Haidenbauer, J., Havranek, M., Ivanov, A. V., Ivanov, N. Ya., Isupov, A. Yu., Jary, V., Jia, Shi-Hai, Jokovic, D., Kaplii, A., Karpishkov, A. V., Kasianova, E. A., Kekelidze, G. D., Khabarov, S. V., Kharusov, P. R., Khrenov, A. N., Kim, V. T., Kirichkov, N. V., Kirin, D. Yu., Kishchin, I., Klekotko, A., Klopot, Ya., Kluev, A., Kokoulina, E. S., Komarov, V. I., Kondratenko, A. M., Kondratenko, M. A., Konorov, I., Kopylov, Yu. A., Korjik, M. V., Korovkin, P. S., Korzenev, A. Yu., Kostukov, E. V., Kotzinian, A., Kovalenko, A. D., Kovalenko, V. N., A., Kozhin M., Kramarenko, V. A., Kruglov, V. N., Kubankin, A., Kubankin, Yu., Kuleshov, S., Kovtun, V. E., Kulikov, A. V., Kurbatov, V. S., Kurjata, R., Kutuzov, S. A., Kuznetsova, E. V., Ladygin, E. A., Ladygin, V. P., Larionova, D. M., Lednicky, D., Lednicky, R., Li, Pei-Yu, Li, Xiao-Mei, Lobko, A. S., Luschevskaya, E., L'vov, A. I., Lyashchenko, V. N., Lysan, V. M., Lyubovitskij, V., Maggiora, A., Maleev, V. P., Maltsev, A., Malykhina, T. V., Makankin, A. M., Makarenko, V. V., Maletic, D., Malkevich, D. B., Marcisovsky, M., Martovitsky, E. V., Marzec, J., Merkin, M. M., Meshcheriakov, G. V., Mitrankov, Yu. M., Mitrankova, M. M., Mitrofanov, E. O., Morozov, B., Moshkovsky, I. V., Movsisyan, A., Nagorniy, S. N., Nechaeva, P. Yu., Nefedov, M. A., Nefedov, Yu. A., Negodaev, M. A., Neue, G., Nikiforov, D. N., Nikitin, V. A., Nikolaev, A. S., Oleynik, D. A., Ososkov, G. A., Panzieri, D., Parsamyan, B., Parzhitsky, S. S., Pastuszak, G., Pavlov, V. V., Pavlova, A. A., Pelevanyuk, I. S., Perepelkin, E. E., Peshekhonov, D. V., Petrosyan, A. Sh., Piskun, A. A., Plotnikov, V. V., Podgainy, D. V., Polozov, P., Polyakova, R. V., Polyansky, V. V., Popov, V. V., Popule, J., Prochazka, I., Prokhorov, I. K., Reva, S. N., Reznikov, S. G., Rezvaya, E. P., Richard, J. -M., Rogachevsky, O. V., Romanov, V. M., Rudenko, A. I., Rumyantsev, M. A., Rusinov, V., Rybakov, N. A., Rychter, A., Rymbekova, A., Safonov, A. B., Salamatin, K. M., Saleev, V. A., Samartsev, A. G., Savenkov, A. A., Savic, M., Semak, A. A., Shaikovsky, V. N., Shavrin, A. A., Sheremeteva, A. I., Shimanskii, S. S., Shipilova, A. V., Shtejer, K., Shulyakovsky, R., Sinitsa, A. A., Skachkov, N. B., Skachkova, A. N., Slunecka, M., Sluneckova, V., Solin, A. A., Solin, A. V., Song, Jin-Xin, Sotnikov, V. V., Sun, Peng-Fei, Starikova, S. Yu., Stavinskiy, A. V., Streletskaya, E. A., Strikman, M., Strusik-Kotlozh, D., Suchkov, S. I., Sultanov, R. I., Sun, Hao, Svirida, D. N., Tarasov, O. G., Tarkovskyi, E. I., Temerbayev, A., Terekhin, A. A., V., Tereschenko V., R., Terkulov A., V., Teryaev O., V., Tishevsky A., V., Tkachenko A., Tokmenin, A. A. V. V., Tomasek, L., Tomasi-Gustafsson, E., Topchiev, N. P., Topilin, N. D., Topko, B. L., Tosello, F., Trifonov, A., Troyan., Yu. A., Trunov, N. O., Tsenov, R., Usenko, E. A., Uzhinsky, V. V., Uzikov, Yu. N., Valiev, F. F., Vasilieva, E. V., Vechernin, V. V., Verkheev, A. Yu., Vertogradov, L. S., Vertogradova, Yu. L., Vesenkov, V. A., Virius, M., Volchansky, N. I., Volkov, I. S., Volkov, P. V., Vorobiev, A., Vrba, V., Wang, Qian, Yudin, I. P., Zamora, J., Zamyatin, N. I., Zaremba, K., Zelenov, A. V., Zemlyanichkina, E. V., Zhang, Yun-Yu, Zhang, Jun-Wei, Zhao, Ming-Rui, Zhao, Qiang, Zhi, Yu, Zhemchugov, A. S., Zhevlakov, A., Zhigareva, N. M., Zhmurin, P. N., Zhukov, I. A., Zhuravlev., N. I, Ziembicki, M., Zinin, A. V., Zubarev, E. V., and Zuev, M. I.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The Spin Physics Detector, a universal facility for studying the nucleon spin structure and other spin-related phenomena with polarized proton and deuteron beams, is proposed to be placed in one of the two interaction points of the NICA collider that is under construction at the Joint Institute for Nuclear Research (Dubna, Russia). At the heart of the project there is huge experience with polarized beams at JINR. The main objective of the proposed experiment is the comprehensive study of the unpolarized and polarized gluon content of the nucleon. Spin measurements at the Spin Physics Detector at the NICA collider have bright perspectives to make a unique contribution and challenge our understanding of the spin structure of the nucleon. In this document the Conceptual Design of the Spin Physics Detector is presented.

Published
2021

10. Electromagnetic secondaries and punch-through effects in the CMS ME1/1

Author

Belotelov, I. I., Golunov, A. O., Golutvin, I. A., Gorbunov, N. V., Karjavin, V. Yu., Kiryushin, Yu. T., Kamenev, A. Yu., Khabarov, S. V., Khabarov, V. V., Mescheryakov, G. V., Moissenz, K. P., Moissenz, P. V., Movchan, S. A., Palichik, V. V., Perelygin, V. V., Shmatov, S. V., Smolin, D. A., and Zarubin, A. V.

Published
2007
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12. Cathode strip chamber for CMS ME1/1 endcap muon station

Author

Erchov, Yu. V., Golunov, A. O., Golutvin, I. A., Gorbunov, N. V., Kamenev, A. Yu., Karjavin, V. Yu., Khabarov, S. V., Khabarov, V. S., Kiryushin, Yu. T., Kurenkov, A. M., Kurenkov, A. A., Ladygin, V. P., Lysiakov, V. N., Mescheriakov, G. V., Moissenz, P. V., Moissenz, K. P., Movchan, S. A., Perelygin, V. V., Rashevsky, V. P., Samsonov, V. A., Slepnev, I. V., Smolin, D. A., Vassiliev, S. E., Vasiliev, T. A., Zarubin, A. V., and Zubarev, E. V.

Published
2006
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19. The Spin Studies in Few-Body Systems at Nuclotron

Author

Ladygin, V. P., primary, Dobrin, I., additional, Fimushkin, V. V., additional, Finogenov, D. A., additional, Genchev, S. G., additional, Gurchin, Yu. V., additional, Ierusalimov, A. P., additional, Isupov, A. Yu., additional, Itoh, K., additional, Janek, M., additional, Karpechev, E. V., additional, Karachuk, J.-T., additional, Khabarov, S. V., additional, Kawabata, T., additional, Khrenov, A. N., additional, Krasnov, V. A., additional, Kurepin, A. B., additional, Kurilkin, A. K., additional, Kurilkin, P. K., additional, Ladygina, N. B., additional, Lipchinski, D., additional, Livanov, A. N., additional, Maeda, Y., additional, Malakhov, A. I., additional, Martinska, G., additional, Piyadin, S. M., additional, Popovichi, J., additional, Prokofichev, A. N., additional, Rapatsky, V. L., additional, Reshetin, A. I., additional, Reznikov, S. G., additional, Rukoyatkin, P. A., additional, Sakaguchi, S., additional, Sakai, H., additional, Sasamoto, Y., additional, Sekiguchi, K., additional, Skhomenko, Ya. G., additional, Suda, K., additional, Syschenko, V. V., additional, Tarjányiová, G., additional, Terekhin, A. A., additional, Uesaka, T., additional, Urban, J., additional, Vasiliev, T. A., additional, Vnukov, I. E., additional, Zamiatin, N. I., additional, and Zubarev, E. V., additional

Published
2016
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20. Study of strange matter production in the heavy ion collisions at NUCLOTRON

Author

Ablyazimov, Timur O., Aichelin, J., Andreev, V. V., Avdejchikov, V. V., Averianov, A. V., Avramenko, S. V., Akishina, V. P., Akishin, P. G., Aksinenko, V. D., Alfeev, A. V., Alfeev, V. S., Babkin, V. A., Baginyan, S. A., Balandin, V. P., Baranova, A. V., Barznat, M. I., Basylev, S. N., Belyakov, Dmitry V., Bogdanova, G. A., Boguslavsky, I. V., Bolshakova, I. A., Boos, E. E., Bratkovskaya, Elena L., Cassing, W., Chernenko, S. P., Davkov, V., Davkov, K., Demidova, V. I., Deng, Z., Derenovskaya, O. Yu., Donskov, S. V., Dunin, V. B., Ershov, A. A., Fateev, O. V., Fedorov, Yu. I., Gapienko, V. A., Gavrishuk, O. P., Genchev, S. G., Golovatyuk, V. M., Golokhvastov, A. I., Golovnya, S. N., Grigalashvili, N., Guber, F. F., Gudima, K. K., Gumen, S., Gurchin, Yu. V., Hartnack, Christoph, Hayduchok, V., Heuser, J., Huang, X., Ivanov, V. V., Ivashkin, A. P., Ierusalimov, A. P., Ilgenfritz, E.-M., Isupov, A. Yu., Ivanets, V., Janek, M., Karachuk, Yu.-T., Karmanov, D. E., Kekelidze, V. D., Kekelidze, G. D., Khabarov, V. S., Khabarov, S. V., Kholodenko, A. G., Khrenov, A. N., Kireev, V. I., Kiryushin, Yu. T., Kisel, P. I., Kisel, Ivan, Kogut, I., Kokoulina, E. S., Kolesnikov, Vadim Ivanovith, Konchakovski, V., Kopko, B., Korolev, M. G., Korotkova, A. M., Kost, Y., Kovaljova, N., Kovtun, V. E., Kozachenko, L., Kravets, M., Kugler, A., Kurbatov, E. O., Kurepin, A. B., Kurilkin, Alexei. K., Kurilkin, Pavel. K., Kushpil, V., Kutov, A. Yu., Kuznezov, A. V., Kuzmin, N. A., Ladygin, E. A., Ladygin, Vladimir P., Ladygina, N. B., Lebedev, A. A., Lenok, V. V., Levchenko, A., Li, Y., Linnyk, O., Lipchinski, D., Litvinenko, E. P., Lobastov, S. P., Lokhtin, I. P., Lukstins, J., Lyashchenko, V. N., Madigozhin, D. T., Makido, O., Maksimenko, N. V., Malakhov, A. I., Malinina, L. V., Martinska, M., Merkin, M. M., Mikhaylov, Yu. V., Mialkovsky, V. V., Moroz, A., Murin, Yu. N., Nagorny, S. N., Nakalov, Y., Nikitin, V. A., Nomokonov, P. V., Okhrimenko, O. V., Palynyak, I., Pavljuchkov, V. V., Parfenov, A. N., Petukhov, Yu. P., Pechenov, V. N., Pechenova, O. Yu., Peshekhonov, V. D., Piyadin, S. M., Polyakov, V. A., Popovichi, J., Radkov, I. S., Radnev, S. V., Rakhlin, L., Raportirenko, A. M., Rashevski, G., Reva, S. N., Reznikov, S. G., Riadovikov, V. N., Rukoyatkin, P. A., Rufanov, I. A., Sadovsky, A. S., Semak, A. A., Senger, P., Shabunov, A. V., Shapovalov, H., Shejnast, V., Shkilyov, A. L., Shurygin, F., Shutov, A. V., Slepnev, V. M., Slepnev, I. V., Snigirev, A. M., Sushko, I., Suzdalev, V. I., Svoboda, O., Syschenko, V. V., Sychkov, S. Yu., Terekhin, A .A., Terlezky, A. V., Teryaev, O. V., Tiflov, V. V., Tikhomirov, V. V., Tlusty, P., Topilin, N. D., Trpisova, B., Tsupa, Yu. P., Turchin, A. A., Tymoshyn, S., Ukhanov, M. N., Usenko, E. A., Urban, J., Vasendina, V. A., Vasiliev, T. A., Vassiliev, Yuri, Vladimirova, N. M., Vishnevsky, A. V., Vnukov, I. E., Vokal, S., Volgin, S. V., Volkov, V. Yu., Vorobiev, A. P., Voronin, A. G., Voronyuk, V. V., Voroshylo, H., Wang, J., Wang, Y., Yerashok, V., Yukaev, A. I., Zagachevskyi, Y., Zaljyubovsky, I. I., Zanevsky, Yu. V., Zenkov, A., Zhu, X., Zinchenko, A. P., Zrelov, P. V., and Zryuev, V. N.

Subjects
Physics::Instrumentation and Detectors, Nuclear Theory, ddc:530, Nuclear Experiment
Abstract

It is proposed to install an experimental setup in the fixed-target hall of the Nuclotron with the final goal to perform a research program focused on the production of strange matter in heavyion collisions at beam energies between 2 and 6 A GeV. The basic setup will comprise a large acceptance dipole magnet with inner tracking detector modules based on double-sided Silicon micro-strip sensors and GEMs. The outer tracking will be based on the drift chambers and straw tube detector. Particle identification will be based on the time-of-flight measurements. This setup will be sufficient perform a comprehensive study of strangeness production in heavy-ion collisions, including multi-strange hyperons, multi-strange hypernuclei, and exotic multi-strange heavy objects. These pioneering measurements would provide the first data on the production of these particles in heavy-ion collisions at Nuclotron beam energies, and would open an avenue to explore the third (strangeness) axis of the nuclear chart. The extension of the experimental program is related with the study of in-medium effects for vector mesons decaying in hadronic modes. The studies of the NN and NA reactions for the reference is assumed.

Published
2012

22. Programmable active memories in real-time tasks: implementing data-driven triggers for LHC experiments

Author

Belosloudtsev, D. A., Bertin, P. Y., Bock, Rudolf K., Boucard, Philippe, Dörsing, Volker, Kammel, Peter, Khabarov, S. V., Klefenz, Frank, Krischer, Werner, Kugel, Andreas, Männer, Reinhard, Noffz, Klaus-Henning, Moll, Laurent, Vuillemin, Jean, Lundheim, Lars, and Zoz, Ralf

Subjects
Physics::Instrumentation and Detectors, 004 Informatik
Abstract

The future Large Hadron Collider (LHC), to be built at CERN, presents among other technological challenges a formidable problem of real-time data analysis. At a primary event rate of 40 MHz, a multi-stage trigger system has to analyze data to decide which is the fraction of events that should be preserved on permanent storage for further analysis. We report on implementations of local algorithms for feature extraction as part of triggering, using the detectors of the proposed ATLAS experiment as a model. The algorithms were implemented for a decision frequency of 100 kHz, on different data-driven programmable devices based on structures of field- programmable gate arrays and memories. The implementations were demonstrated at full speed with emulated input, and were also integrated into a prototype detector running in a test beam at CERN, in June 1994.

Published
1995

24. Study of strange matter production in the heavy ion collisions at NUCLOTRON

Author

Ladygin, V., Ablyazimov, T. O., Aichelin, J., Andreev, V. V., Avdejchikov, V. V., Averianov, A. V., Avramenko, S. V., Akishina, V. P., Akishin, P. G., Aksinenko, V. D., Alfeev, A. V., Alfeev, V. S., Babkin, V. A., Baginyan, S. A., Balandin, V. P., Baranova, A. V., Barznat, M. I., Basylev, S. N., Belyakov, D. V., Bogdanova, G. A., Boguslavsky, I. V., Bolshakova, I. A., Boos, E. E., Bratkovskaya, E. L., Cassing, W., Chernenko, S. P., Davkov, V., Davkov, K., Demidova, V. I., Deng, Z., Derenovskaya, O. Yu, Donskov, S. V., Dunin, V. B., Ershov, A. A., Fateev, O. V., Fedorov, Yu I., Gapienko, V. A., Gavrishuk, O. P., Genchev, S. G., Golovatyuk, V. M., Golokhvastov, A. I., Golovnya, S. N., Grigalashvili, N., Guber, F. F., Gudima, K. K., Gumen, S., Gurchin, Yu V., Christoph Hartnack, Hayduchok, V., Heuser, J., Huang, X., Ivanov, V. V., Ivashkin, A. P., Ierusalimov, A. P., Ilgenfritz, E. -M, Isupov, A. Yu, Ivanets, V., Janek, M., Karachuk, Yu -T, Karmanov, D. E., Kekelidze, V. D., Kekelidze, G. D., Khabarov, V. S., Khabarov, S. V., Kholodenko, A. G., Khrenov, A. N., Kireev, V. I., Kiryushin, Yu T., Kisel, P. I., Kisel, I. V., Kogut, I., Kokoulina, E. S., Kolesnikov, V. I., Konchakovski, V., Kopko, B., Korolev, M. G., Korotkova, A. M., Kost, Y., Kovaljova, N., Kovtun, V. E., Kozachenko, L., Kravets, M., Kugler, A., Kurbatov, E. O., Kurepin, A. B., Kurilkin, A. K., Kurilkin, P. K., Kushpil, V., Kutov, A. Yu, Kuznezov, A. V., Kuzmin, N. A., Ladygin, E. A., Ladygin, V. P., Ladygina, N. B., Lebedev, A. A., Lenok, V. V., Levchenko, A., Li, Y., Linnyk, O., Lipchinski, D., Litvinenko, E. P., Lobastov, S. P., Lokhtin, I. P., Lukstins, J., Lyashchenko, V. N., Madigozhin, D. T., Makido, O., Maksimenko, N. V., Malakhov, A. I., Malinina, L. V., Martinska, M., Merkin, M. M., Mikhaylov, Yu V., Mialkovsky, V. V., Moroz, A., Murin, Yu N., Nagorny, S. N., Nakalov, Y., Nikitin, V. A., Nomokonov, P. V., Okhrimenko, O. V., Palynyak, I., Pavljuchkov, V. V., Parfenov, A. N., Petukhov, Yu P., Pechenov, V. N., Pechenova, O. Yu, Peshekhonov, V. D., Piyadin, S. M., Polyakov, V. A., Popovichi, J., Radkov, I. S., Radnev, S. V., Rakhlin, L., Raportirenko, A. M., Rashevski, G., Reva, S. N., Reznikov, S. G., Riadovikov, V. N., Rukoyatkin, P. A., Rufanov, I. A., Sadovsky, A. S., Semak, A. A., Senger, P., Shabunov, A. V., Shapovalov, H., Shejnast, V., Shkilyov, A. L., Shurygin, F., Shutov, A. V., Slepnev, V. M., Slepnev, I. V., Snigirev, A. M., Sushko, I., Suzdalev, V. I., Svoboda, O., Syschenko, V. V., Sychkov, S. Yu, Terekhin, A. A., Terlezky, A. V., Teryaev, O. V., Tiflov, V. V., Tikhomirov, V. V., Tlusty, P., Topilin, N. D., Trpisova, B., Tsupa, Yu P., Turchin, A. A., Tymoshyn, S., Ukhanov, M. N., Usenko, E. A., Urban, J., Vasendina, V. A., Vasiliev, T. A., Vassiliev, Yu, Vladimirova, N. M., Vishnevsky, A. V., Vnukov, I. E., Vokal, S., Volgin, S. V., Volkov, V. Yu, Vorobiev, A. P., Voronin, A. G., Voronyuk, V. V., Voroshylo, H., Wang, J., Wang, Y., Yerashok, V., Yukaev, A. I., Zagachevskyi, Y., Zaljyubovsky, I. I., Zanevsky, Yu V., Zenkov, A., Zhu, X., Zinchenko, A. P., Zrelov, P. V., and Zryuev, V. N.

25. Investigation of the light nuclei spin structure from hadronic channels at NUCLOTRON

Author

Kurilkin, P. K., Dobrin, I., Fimushkin, V. V., Finogenov, D. A., Genchev, S. G., Gurchin, Yu V., Ierusalimov, A. P., Isupov, A. Yu, Itoh, K., Janek, M., Karpechev, E. V., Karachuk, J. -T, Khabarov, S. V., Takahiro KAWABATA, Khrenov, A. N., Krasnov, V. A., Kurepin, A. B., Kurilkin, A. K., Ladygin, V. P., Ladygina, N. B., Lipchinski, D., Livanov, A. N., Maeda, Y., Malakhov, A. I., Martinska, G., Piyadin, S. M., Popovichi, J., Prokofichev, A. N., Rapatsky, V. L., Reshetin, A. I., Reznikov, S. G., Rukoyatkin, P. A., Sakaguchi, S., Sakai, H., Sasamoto, Y., Sekiguchi, K., Skhomenko, Ya G., Suda, K., Syschenko, V. V., Tarjányiová, G., Terekhin, A. A., Uesaka, T., Urban, J., Vasiliev, T. A., Vnukov, I. E., Zamiatin, N. I., and Zubarev, E. V.

26. GEM Letter of Intent

Author

Steiner, R., Negret, J. P., Forden, G. E., Rutherfoord, J. P., Shaver, L., Shupe, M. A., Chen, G., Dai, Z. Z., Dong, X. Y., Gao, Y. C., Li, T. Z., Liu, G. T., Liu, Z. Q., Man, S. Q., Ren, S. X., Su, Z. L., Wang, Y. T., Wen, O., Xiao, H., Yang, H. Z., Zhang, F. C., Zhang, F. Y., Zhang, J., Zhang, J. Q., Zheng, Y. N., Jiang, D., Lai, C., Liu, H., Xia, S., Ye, Y., Gu, W., Gu, Y., Guo, Y., Huang, Y., Li, J., Mao, C., Sheng, H., Xu, R., Zhang, D., Zhuang, B., Ahlen, S. P., Booth, E., Carey, R., Dye, S., Golden, M., Hazen, T., Higby, D., Johnson, T., Lane, K. D., Marin, A., Miller, J. P., Osborne, D., Robert Wilson, Shank, J., Stone, J. L., Sulak, L. R., Warner, D., Whitaker, John Scott, Wilson, R. J., Worstell, W. A., Zhou, B., Atiya, M. S., Chiang, I-H, Gibbard, B., Gordon, H., Haggerty, J. S., Kahn, S., Kraner, H. W., Kroon, P., Lissauer, D., Littenberg, L. S., Ma, H., Makowiecki, D., Murtagh, M. J., O Connor, P., Paffrath, L., Paige, F. E., Polychronakos, V. A., Protopopescu, S., Radeka, V., Rahm, D. C., Rankowitz, S., Rehak, P., Rescia, S., Rogers, L., Samios, N. P., Stephani, D., Stumer, I., Takai, H., Tannenbaum, M. J., Woody, C. L., Yamin, S. P., Widgoff, M., Besliu, C., Aculai, A., Blaj, C., Bozdog, H., Butacu, L., Ciobanu, M., Dorobantu, A., Ighicianu, D., Pascovici, G., Popa, V., Radulescu, G., Spanu, D., Stan-Sion, C., Valeanu, V., Zimmer, K., Branson, J. G., Brower, W., Kobrak, H. E. G., Masek, R., Paar, H. P., Swanson, R. A., Sivertz, M., Barish, B. C., Gratta, G., Gruenewald, M., Kirkby, David P., Lu, W., Mount, R., Newman, H. B., Shevchenko, S., Shi, X., Wei, Z. Y., Yamamoto, H., Zhu, R. Y., Clemen, M. J., Edelstein, R., Engler, A., Ferguson, T., Kraemer, R. W., Russ, J. S., Sutton, R. B., Vogel, H., Hahn, C. H., Jang, H. I., Kim, J. Y., Kim, T. I., Lim, I. T., Pac, M. Y., Castilla-Valdez, H., Herrera-Corral, G., Au, Y., Aprile, E., Bolotnikov, A., Bolton, T., Chen, D., Leltchouk, M., Moulsen, M., Mukherjee, R., Parsons, J., Rowson, P. C., Seman, M., Shaevitz, M., Sippach, W., Willis, W., Kapoor, V., Shivpuri, R. K., Ayer, F., Elder, C., Hamilton, T., Hansberry, M., Nimblett, F., Sullivan, D., Womble, E., Lane, Charles E., Alekseev, G. D., Bannikov, A. V., Barabash, L. S., Baranov, S. A., Belosludtsev, D. A., Bonyushkin, Yu E., Bychkov, V. N., Chelkov, G. A., Ershov, Yu V., Frolov, V., Golutvin, I. A., Gorbunov, N. V., Gornushkin, Yu A., Kalinnikov, V. A., Kapishin, M. N., Karev, A. G., Karzhavin, V. Yu, Kazarinov, M. Yu, Kekelidze, V. D., Khabarov, S. V., Khabarov, V. S., Khomenko, B. A., Khovansky, N. N., Kiryushin, Yu T., Klimov, O., Korytov, A. V., Kotov, V. M., Krumshtein, Z. V., Kulinich, P. A., Kvirikashvili, G. A., Lysiakov, V. N., Lyubin, A. L., Makhankov, A. V., Malyshev, V. L., Merekov, Yu P., Movchan, S. A., Nozdrin, A. A., Odishvili, A. K., Olshevski, A. G., Peshekhonov, V. D., Petukhov, Yu P., Popov, A. A., Pose, D., Predo, T., Progulova, T. G., Sashin, V. A., Sedykh, Yu V., Selyunin, S. Yu, Smolin, D. A., Spaskov, V. N., Tatishvili, G. T., Tkachev, L. G., Tokmenin, V. V., Vertogradov, L. S., Vishnevsky, A. V., Yamburenko, V. S., Zinchenko, A. I., Winn, D. R., Gonzalez, A., Morelos Pineda, Antonio, Moreno, G., Villasenor, L., Ryu, J. Y., Chung, K. S., Chung, S. H., Park, I. G., Song, J. S., Yoon, C. S., Fretwurst, E., Lindstrom, G., Riech, V., Carlson, E., Simmons, Elizabeth H., Bian, Z. H., Cai, M. F., Fang, Y. M., Han, R. D., Hao, L. Y., Lin, X. S., Liu, B. A., Mei, W., Shi, Q. C., Wang, H. M., Wang, Z. M., Wu, S. L., Xing, S. L., Xu, J. H., Xu, X. L., Xu, K. Z., Yang, B. X., Ye, B. J., Yu, X. Q., Zhou, Y. Z., Lau, K., Mayes, B. W., Pinsky, Lawrence S., Pyrlik, J., Weinstein, R., Akchurin, N., Kadrmas, D., Langland, K., Mccliment, E. R., Meurice, Y., Olchowski, F., Onel, Y., Reno, M., Rodgers, V., Alyea, E. D., Bower, C., Gephard, M., Heinz, R. M., Mufson, Stuart L., Musser, J., Nutter, S., Pitts, J., Chang, S. D., Cheon, B. G., Cho, J. H., Kim, C. O., Kim, T. Y., Lee, S. B., Nam, S. W., Vasilev, Mikhail A., Ables, E., Bionta, R., Bowers, J. M., Britt, H. C., Capell, M. H., Chargin, A. K., Deis, G. A., Fackler, O. D., Heim, J., Johnson, C., Lowry, M., Mcconaghy, C. F., Mugge, M., Skulina, K. M., Bibber, K., Wenaus, T. J., Wineman, S., Wuest, C. R., Tikhomirov, V., Barber, R., Boissevain, J. G., Brooks, M., Brown, D., Coan, T., Farber, R. M., Hahn, S. F., Kapustinsky, J., Kinnison, W. W., Lackner, K. S., Lapedes, A. S., Lee, D. M., Maier, W. B., Mills, Geoffrey B., Sanders, G. H., Sharp, D., Smith, B., Sommer, W. F., Sondheim, W. E., Mcneil, R., Moom, K. H., Coulson, J., Digiacomo, N. J., Easom, B., Killian, K., Mason, L., Burrows, P., Busza, W., Chang, Y-H, Chen, M., Ding, H., Friedman, J. I., Gaudreau, M. P. J., Hafen, Elizabeth S., Haridas, P., Kelsey, J., Kendall, H., Lebedenko, V., Montgomery, D. B., Osborne, L. S., Pless, I. A., Randall, Lisa, Rosenson, L., Shuvalov, R., Sullivan, J. D., Sumorok, S., Taylor, F. E., Verdier, R., Wadsworth, B., Yan, X. J., Zhang, X., Levin, D., Mckee, S., Tarle, G., Tomasch, A., Abolins, M. A., Bromberg, C., Miller, R. J., Cremaldi, L. M., Moore, B., Reidy, J. J., Balagura, V., Bolozdynya, A., Efremenko, Y., Golutvin, A., Gorichev, P., Gusev, L., Kamyshkov, Yuri A., Korolko, I., Kouchenkov, A., Kovalenko, A., Laptin, L., Murat, P., Nagovitsyn, V., Nepeipivo, A., Ostapchuk, A., Ratnikov, F., Savin, A., Shmakov, K., Tikhomirov, I., Chernyshev, V., Chistilin, V., Vinogradov, V. A., Barkov, L., Grigorev, D., Khazin, B., Klimenko, S., Kuraev, E., Lelchouk, M., Malyshev, V., Maslennikov, A., Redin, S., Shatunov, Yu, Solodov, E., Onuchin, A., Panin, V., Peleganchuk, S., Sidorov, V., Tikhonov, Yu, Baturitsky, M., Degtiarev, A., Kubasov, A., Mikhailov, V., Shuljak, V., Shumeiko, N., Grigorev, V., Nevsky, P., Potekhin, M., Sumarokov, A., Chernyatin, V., Vanyashin, A., Arodzero, A. A., Bashindzhagian, G., Ermolov, P. F., Fisyak, Yuri V., Larichev, A. N., Merkin, M. M., Murzin, V. S., Sotnikova, N. A., Voronin, A. G., Zotkin, S. A., Zhukov, V. Yu, Kim, S. N., Buchholz, D., Gobbi, B., Schellman, H., Bauer, M. L., Chae, S., Cohn, H. O., Eberle, C., Moore, J., Plasil, F., Read, K., Rennich, M., Todd, R. A., Young, K., Brau, J. E., Frey, R., Furuno, K., Strom, David M., Zeitlin, C. J., Cleland, W., Stern, E., Denes, P., Ito, M., Marlow, Daniel R., Suzuki, M., Takahashi, T., Ferbel, T., Fanourakis, G., Zielinski, M., Jacques, P., Kalelkar, M., Plano, R. J., Stamer, P., Word, G. B., Grachev, V. T., Krivshich, A. G., Prokofev, O. E., Samsonov, V. M., Sarantsev, V. V., Terentev, N. K., Masuda, K., Shibamura, E., Eboli, Oscar J. P., Escobar, C. O., Gouffon, P., Luksys, M., Novaes, S. F., Fang, X. L., Gu, P. X., Guo, J. K., Hu, G. Q., Hua, S. K., Ji, Z. D., Li, P. J., Shen, D. Z., Shen, G. S., Shi, E. W., Su, W. T., Xie, Y. Y., Xu, L., Xue, Z. L., Yan, D. S., Yin, Z. W., Yuan, X. L., Zhao, G. M., Zhao, Y. L., Zhong, W. Z., Zhou, R. M., Bao, J., Cao, D., Chen, S., Li, X. P., Lin, S., Rong, T., Shen, L. R., Sheng, K., Wan, H., Yu, F. H., Zheng, W. H., Zhu, D., Zhu, F., Park, J. N., Rosenfeld, C., Wilson, J. R., Olness, Fredrick I., Stroynowski, R., Teplitz, V., Cormell, L. R., Dingus, P., Harris, M., Kuzminski, J., Maschke, A. W., Mcfarlane, W. K., Mehta, N., Meinke, R., Mitselmakher, Guenakh, Morgan, K., Parker, B., Roberts, L. A., Scipioni, B., Soundranayagam, R., Stocker, F., Thomas, J., Vaniachine, A., Yost, G. P., Alam, M. S., Kim, I. J., Ling, Z. C., Nemati, B., O Neill, J., Severini, H., Sun, Chih-Ree, Engelmann, R., Jung, C. K., Marx, M. D., Mccarthy, R. L., Mohammadi, M., Rijssenbeek, M., Yanagisawa, C., Fox, G. C., Furmanski, W., Haupt, T., Goldberg, J., Amaglobeli, N. S., Dzhordzhadze, W. P., Mchedlishvili, A. J., Mzavia, D. A., Shanidze, R. G., Tkebuchava, F. G., Alexander, G., Beck, A., Bella, G., Benary, O., Cohen, I., Etzion, E., Heifetz, R., Oren, Y., Paz, N., Berridge, S., Bugg, W. M., Du, Y. C., Kroeger, R., Tsveybak, I., Weidemann, A., Kettell, Steven H., Allen, C. C., Hoffmann, G. W., Lang, K., Marcin, M. R., Ritchie, J. L., Gagliardi, C., Glass, G., Tribble, R., Webb, R. C., Chen, L. Y., Du, J., Gu, M., Wang, J., Wang, L. M., Wu, X., Xiang, K. H., An, J., Kang, K., Lin, Y., Liu, G., Mai, D., Ni, W., Shang, R., Xu, S., Xu, Z., Panvini, R. S., Venuti, J. P., Schwarz, C., Doke, T., Hitachi, A., Ishida, N., Kashiwagi, T., Kikuchi, J., Cook, V., Eisenberg, J., Forbush, D., Mockett, P. M., Sutlief, S., Toevs, F., Beatty, J., Binns, W., Crary, D., Ficenec, D., Klarmann, J., Bahk, S. Y., Adair, R. K., Baltay, C., Ben-David, R., Emmett, W., Kasha, H., Manly, S. L., Sen, S., and Turk, J.

28. [The effectiveness of the transcranial electrical stimulation method in obstetrics and gynecology].

Author

Khabarov SV, Khadartseva KA, and Panshina MV

Subjects
Brain, Female, Humans, Pregnancy, Genital Diseases, Female, Gynecology, Obstetrics, Transcranial Direct Current Stimulation
Abstract

The review examines the use of protective (endorphinergic and serotonergic) mechanisms of the brain in obstetrics and gynecology. To review the current state of the problem an analysis of the eLIBRARU, PubMed, Embase, MEDLINE, Cochrane databases was carried out, and works for 2015-2020 were selected. It has been shown that the method of non - invasive non - drug effects on the human body - transcranial electrical stimulation (TES) - activates and accelerates reparative processes, normalizes psychophysiological status, has anti-inflammatory and immune-stimulating effects, has an onco-protective effect, stabilizes the autonomic nervous system, provides drug - free disturbance homeostasis in general. This makes it possible to successfully use TES in obstetrics and gynecology in such pathological conditions as the threat of pregnancy termination at different times, nausea and vomiting of pregnant women, preeclampsia, pathological prelaminar period, menstrual dysfunction, climacteric syndrome, leiomyoma and endometriosis of the uterus, endometrial hyperplastic processes, chronic inflammatory diseases of the pelvic organs with pain syndrome, surgery and obstetrics care. TES is characterized by high efficiency, safety, ease of use, availability and economic profitability. TES reduces the number of prescribed drugs and shortens the recovery time. This method is used both as monotherapy and as a component of a complex action including medication and non-medication. The results of the TES studies presented in the review complement each other and demonstrate the importance of modern alternative methods of treatment, and the authors of these studies are unanimous in their opinion on the fruitfulness of the use of transcranial electrical stimulation as a type of non-drug therapy in various fields of obstetrics and gynecology.

Published
2021
Full Text
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29. [New approaches to search for antitumoral compounds].

Author

Gerasimova GK, Apryshko GN, Reshetnikova VV, Sidorova TA, Solntseva TI, Khorosheva EV, Khabarov SV, and Baryshnikov AIu

Subjects
Antineoplastic Agents pharmacokinetics, Humans, Mass Screening methods, Antineoplastic Agents chemistry, Antineoplastic Agents pharmacology, Drug Therapy trends, Neoplasms epidemiology
Abstract

The authors discuss the present-day state of search for antitumoral compounds at Blokhin Russian Oncological Research Center and promising approaches including computer technologies as means of search for new anticancerous targets and drugs.

Published
2007

30. [A novel immunoregulating hexapeptide with antineoplastic effect].

Author

Treshchalina EM, Sedakova LA, Vlasenkova NK, Zhukova OS, Firsova GA, Mikhaĭlova LM, Kolesnikova EIu, Zimakova NI, Khabarov SV, and Gerasimova GK

Subjects
Adjuvants, Immunologic pharmacokinetics, Animals, Antineoplastic Agents pharmacokinetics, Cell Division drug effects, Female, Humans, Immunologic Factors pharmacology, Leukemia P388 drug therapy, Male, Mammary Neoplasms, Experimental drug therapy, Melanoma, Experimental drug therapy, Mice, Mice, Inbred BALB C, Mice, Inbred DBA, Oligopeptides pharmacokinetics, Sarcoma 180 drug therapy, T-Lymphocytes drug effects, Tumor Cells, Cultured, Adjuvants, Immunologic pharmacology, Antineoplastic Agents pharmacology, Neoplasms, Experimental drug therapy, Oligopeptides pharmacology
Abstract

A synthesized analog of myelopeptide HP-2-->M[symbol: see text]-2 (Leu-Val-Val-Tyr-Pro-Trp) caused a significant (60-80%) and prolonged inhibition of s.c. grafted tumors P388, Ca-755, B-16 and sarcoma 180 in isogenic mice but did not affect the growth of tumor B-16 in nude mice. Nor did it influence proliferative activity or viability of cultured human tumor cells. The best results were obtained with s.c. injections of 0.5-2 mg/kg HP-2-->M[symbol: see text]-2, twice or trice a day, at 96 hr intervals. No symptoms of severe poisoning were registered at doses of HP-2-->M[symbol: see text]-2 100 times the therapeutic one. A pharmacokinetic study in mice revealed prolonged circulation of HP-2-->M[symbol: see text]-2 in blood and a high affinity for the bone marrow (t 1/2 (130.1 hr and 431.6 hr, respectively). HP-2-->M[symbol: see text]-2 restored in vitro the ascites P388-suppressed cytotoxicity of murine T-lymphocytes. HP-2-->M[symbol: see text]-2 is regarded as a candidate for clinical studies of its potential of immunocorrection in cancer patients suffering T-lymphocyte immunity disturbances.

Published
2001

31. [Effect of anti-tumor agents cisplatin and cycloplatam on membrane protein kinase C activity in murine T-lymphocytes].

Author

Khabarov SV and Gerasimova GK

Subjects
Animals, Cell Membrane drug effects, Cell Membrane enzymology, Mice, Mice, Inbred DBA, Protein Kinase C metabolism, T-Lymphocytes enzymology, Antineoplastic Agents pharmacology, Cisplatin pharmacology, Organoplatinum Compounds pharmacology, Protein Kinase C drug effects, T-Lymphocytes drug effects
Abstract

The effect of cisplatin and the new drug cycloplatam (amine (cyclopentylamine)-S-(-)-malatoplatinum (II)) on protein kinase C (PKC) activity and Ca(2+)-dependent binding of PKC to T lymphocytes membranes was studied in vivo and in vitro. At first, the effect of the drugs on PKC activity of intact and activated lymphocytes was studied in vivo. In 48 hours after intraperitoneal injection of mice with therapeutic doses of the drugs, PKC activity of intact lymphocytes was differentially affected. Cisplatin did not practically alter the enzyme activity, whereas cycloplatam inhibited the PKC activity by 37% versus control. In lymphocytes activated by mouse P-388 leukemia cells in vivo, the drugs caused almost complete suppression of PKC activity and Ca(2+)-dependent binding of the enzyme to the membranes. The drugs were effective in intact cells. After incubation of intact lymphocytes in vitro for 24 hours with cisplatin or cycloplatam (10(-5)M), PKC activity was increased 1.62- and 1.35-fold, respectively, versus control. Ca(2+)-dependent binding of the enzyme to the membranes was also increased 1.61- and 1.36-fold by cisplatin and cycloplatam, respectively. On the contrary, at 10(-4) M concentration under similar conditions, the drugs did not affect the PKC activity of the lymphocytes. Furthermore, cycloplatam, unlike cisplatin, reduced the PKC binding to cellular membranes by 31%. The mechanisms of the drugs effects on PKC activity are suggested. The data indicate that increase or decrease of PKC activity induced by the drugs cause stimulation or depression of functional activity of T lymphocytes, respectively. Thus, the membrane-bound PKC can play the key role in initiation and development of immunomodulatory effects of cisplatin and cycloplatam.

Published
1996

32. [Characteristics of beta-adrenoreceptors of L-1210 leukemia and its sarcolysine-resistant variant].

Author

Khabarov SV

Subjects
Adenylyl Cyclases metabolism, Animals, Cyclic AMP metabolism, Dihydroalprenolol pharmacology, Drug Resistance, Enzyme Activation drug effects, Isoproterenol pharmacology, Leukemia L1210 drug therapy, Melphalan therapeutic use, Mice, Mice, Inbred Strains, Neoplasm Transplantation, Receptors, Adrenergic, beta metabolism, Leukemia L1210 metabolism, Melphalan antagonists & inhibitors, Receptors, Adrenergic, beta drug effects
Abstract

Beta-adrenoceptors have been discovered on the surface of cells of leukaemia L1210 and its variant resistant to sarcolysine (D, L-melphalan). One type of functionally active receptors with dissociation constant Kd for L-[3H] dihydroalprenolol about 0.02 nM and 360 receptors per cell have been revealed in leukaemia L1210 cells. In the resistant cells two types of functionally inactive receptors with Kd1 approximately 0.02 nM (420 receptors per cell) and Kd2 approximately 2.5 nM (3000 receptors per cell) have been revealed. This property of beta-adrenoceptors may be one of the causes of tumour cell resistance to sarcolysine.

Published
1987

33. [Interaction between receptors and biologically active substances in tumor cells].

Author

Solntseva TI, Khabarov SV, and Mikhaevich IS

Subjects
Adrenergic alpha-Antagonists metabolism, Adrenergic beta-Antagonists metabolism, Animals, Binding, Competitive drug effects, Drug Interactions, Kinetics, Ligands, Mice, Neoplasm Transplantation, Receptors, Adrenergic, beta drug effects, Receptors, Cholinergic drug effects, Adrenergic alpha-Antagonists pharmacology, Adrenergic beta-Antagonists pharmacology, Receptors, Adrenergic, beta metabolism, Receptors, Cholinergic metabolism, Sarcoma 37 metabolism, Sarcoma, Experimental metabolism
Published
1986

34. [Interaction of sarcolysine with beta-adrenoreceptors in tumor cells].

Author

Belousova AK, Solntseva TI, and Khabarov SV

Subjects
Adenylyl Cyclases metabolism, Animals, Binding Sites, Binding, Competitive, Dihydroalprenolol metabolism, In Vitro Techniques, Kinetics, Melphalan pharmacology, Mice, Models, Biological, Propranolol metabolism, Receptors, Adrenergic, beta drug effects, Melphalan metabolism, Receptors, Adrenergic, beta metabolism, Sarcoma 37 metabolism, Sarcoma, Experimental metabolism
Abstract

The sites of specific binding of 3H-L-dihydroalprenolol (3H-DHA) were identified on the surface of ascites sarcoma 37 cells, using competitive displacement and binding of the beta-adrenergic antagonists, 3H-DHA and L-propranolol. These binding sites possessed the properties of beta-adrenergic receptors coupled with adenylate cyclase. Analysis of 3H-DHA binding by the Scatchard method revealed the presence of beta-adrenergic receptors of two types, i. e., with a high (Kd = 0.9-1.0 nM) and low (Kd = 15-20 nM) affinity for 3H-DHA. The number of high affinity receptors was (5.0-7.5) X 10(3); that of low affinity receptors was (20-30) X 10(3) on a per cell basis. Sarcolysine at concentrations of 1-10 microM displaced receptor-bound 3H-DHA, competed with the ligand for the common binding sites and caused, similar to isoproterenol, a short-term elevation of the intracellular cAMP content. Sarcolysine within the same concentration range (2.5-25 microM) caused non-competitive inhibition of the cAMP phosphodiesterase (PDE2) activity of plasma membranes isolated from ascites sarcoma 37 cells. The data obtained point to the functional coupling between beta-adrenergic receptors, adenylate cyclase and membraneous PDE2 of tumour cells as well as to its possible role in the antitumour effect of sarcolysine.

Published
1985

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