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In this paper, we study an optimal control problem for a spacefractional wave equation.First, we show the existence and uniqueness of weak solution by Galerkin approximate method.Then, we obtain an optimal control for the optimal control problem.

CASE REPORT: AN UNUSUAL CASE OF LATE ONSET DISSEMINATED STAPHYLOCOCCAL SEPSIS IN A PRETERM INFANT. Shahzad Khattak, Ian Dady, Devdeep MukherjeeNeonatal Intensive Care Unit, St Maryu2019s Hospital, ManchesterBACKGROUND:Percutaneous central venous catheters (PCVC) are commonly used in the neonatal intensive care unit. Preterm infants are more predisposed to develop catheter related blood stream infection (CRBSI) which happens to be the most common complication associated with PCVC.SUMMARY:30 weeks male baby recovering in the neonatal unit was noted to be have increasing oxygen requirement and was ventilated on 10th day of life. Sepsis screen revealed a rising C Reactive protein (CRP) along with thrombocytopenia. Blood culture grew Staphylococcus aureus (SA) and was positive for Panton Valentine Leukocidin (PVL) toxin. Within 24 hours he developed a dusky 4th toe on his right foot and an abscess overlying the antero-medial aspect of his left elbow and another overlying his Xiphisternum. Echocardiography and ophthalmological examination was normal. Magnetic resonance imaging (MRI) of whole body showed cavitating lesions in the right upper lobe, right lung base and also in the left lung. He had a multi loculated collection in the left ante cubital fossa measuring 33x17mm and a lower pre-sternal collection measuring 13x4mm. Baby had a long line in his right arm which was removed as it was believed to be the source of dissemination of the bacteria. He was initially started on Cefotaxime and Vancomycin and later changed to Flucloxacillin and Linezolid as per culture sensitivity. Baby responded well to antibiotics and was discharged without any sequelae.DISCUSSION:Sepsis due to PVL toxin producing SA can cause significant morbidity and mortality in neonates. Proper screening should be done to rule out septic foci in neonates. MRI is a good non-invasive tool to demonstrate multiple septic foci in a patient with disseminated sepsis.