Search

Your search keyword '"Khillare, Chaitnya"' showing total 5 results
Start Over Author "Khillare, Chaitnya"
5 results on '"Khillare, Chaitnya"'

1. DATAANALYSIS OF LABORATORY FINDINGS AND ITS USE IN PREDICTING REQUIREMENT OF OXYGEN IN A COVID 19 POSITIVE PATIENTS AT TERTIARY CARE HOSPITAL IN PUNE MAHARASHTRA

Author

Khillare Chaitnya Dnyanesh, Gogate Bageshri Parikshit, Malwe Yogesh Ramdas, and Sanghvi Ameya Chandrasekar

Subjects
fungi
Abstract

INTRODUCTION:The coronavirus disease 2019 (COVID-19) is caused by the virus SARS-CoV-2 and is declared as a global pandemic by the World Health Organization (WHO). There are many western and Chinese studies have done, but there is a need for research to evaluate the pattern of the haematological parameters of COVID-19 patients & predict requirement of Oxygen in the Indian population. MATERIALS AND METHODS: st A retrospective cross sectional study carried out on 150 COVID-19 positive patients admitted form 1 May th 2021 to 14 May 2021 in a tertiary care hospital, Smt. Kashibai Navale Medical College & General Hospital, India. RESULTS: The nal study population consisted of 150 patients. The Derived NLR and NLR & CRPhad higher specicity and positive predictive value. The accuracy of Derived NLR, NLR and CRPwas 66%, 64% and 63% respectively.The area under the ROC Curve (AUC) values of Derived NLR, NLR, and CRPindicates that there was a 65% probability that these signicant indicators were able to distinguish patients required oxygen or not (on room air). CONCLUSION: History of Diabetes, hypertension plays measure role as a prognostic factor in a COVID 19 Positive. But other hematological parameters like NLR, derived NLR, CRPferritin also plays measure role in predicting requirement of oxygen

Published
2022

2. Study of ER, PR, HER2/neu, p53, and Ki67 expression in primary breast carcinomas and synchronous metastatic axillary lymph nodes

Author

Khande, Tejal, Joshi, Avinash, Khandeparkar, Siddhi, Kulkarni, Maithili, Gogate, Bageshri, Kakade, Aniket, Sahu, Piyush, and Khillare, Chaitnya

Subjects
Tumor proteins -- Prognosis -- Development and progression, Progesterone, Breast cancer -- Development and progression -- Prognosis, Cancer metastasis -- Development and progression -- Prognosis, Estrogens, Carcinoma, Biological markers, Phenols (Class of compounds), Tumors, Sex hormones, Company public relations, Health
Abstract

Byline: Tejal. Khande, Avinash. Joshi, Siddhi. Khandeparkar, Maithili. Kulkarni, Bageshri. Gogate, Aniket. Kakade, Piyush. Sahu, Chaitnya. Khillare Background: Breast cancer (BCA) is the second most common cancer among women in [...]

Published
2020

5. Immunohistochemical expression of vimentin in invasive breast carcinoma and its correlation with clinicopathological parameters.

Author

Khillare, Chaitnya, Sinai Khandeparkar, Siddhi, Joshi, Avinash, Kulkarni, Maithili, Gogate, Bageshri, and Battin, Shivani

Subjects
*ESTROGEN receptors, *POSTMENOPAUSE, *PROGESTERONE receptors, *BREAST, *VIMENTIN
Abstract

Introduction: Breast carcinoma (BCa) is one of the most common cancers among women globally. Increased vimentin expression has been reported in various epithelial cancers. Aim: This study examines the expression of vimentin in BCa and its correlation with various prognostic factors such as tumor size, histological grade, lymph node status, estrogen receptor (ER), progesterone receptor (PR), HER2/neu, and Ki67 status. Materials and Methods: Seventy cases of BCa diagnosed between 2014 and 2015 were included in the study. A technique of manual tissue microarray was employed for the analysis of expression of immunohistochemical (IHC) markers such as vimentin, ER, PR, HER2/neu, and Ki67. Results were subjected to statistical analysis. Results: Vimentin was found positive in 53 (75.7%) cases of BCa, of which 18 cases (25.7%) were triple-negative BCa (TNBC). Positivity for ER, PR, Her2, and Ki67 was 32.8%, 31.4%, 60%, and 99%, respectively. Vimentin expression was significantly associated with ER negativity. All 53 cases expressing vimentin showed positive Ki67 labeling index; however, this was not statistically significant. Maximum vimentin expression was observed in the age group >50 years, postmenopausal women, BCa cases showing lymphovascular invasion (LVI), axillary lymph node metastasis, higher stage and higher grade of tumor, negative PR expression, and positive HER2/neu expression. However, this was not statistically significant. In TNBC, vimentin expression was significantly associated with histological grade and LVI. Conclusion: Vimentin expression was associated with well-established poor prognostic factors of BCa. Vimentin expression if routinely included in histopathology report would aid in better understanding of tumor behavior. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results