790 results on '"Kiaii, Bob"'
Search Results
2. Issues and considerations in perioperative management of robotic coronary bypass grafting.
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Anderson, Devon, Catrip-Torres, Jorge, and Kiaii, Bob
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Robot ,cardiac ,coronary artery bypass surgery ,management ,perioperative - Abstract
Minimally invasive approaches to address coronary artery disease, such as robotic coronary bypass grafting, are emerging in surgery and have been shown to be beneficial with a reduction in morbidity. The perioperative management of this subset of patients is crucial to the success of the operation as there are several preoperative and postoperative issues and considerations that need to be addressed. A meticulous preoperative workup with an extensive history, physical exam, and appropriate imaging are instrumental to ensure a successful operation. Protocolized postoperative care is also essential to garnish the most benefit from this minimally invasive approach. All of these factors, in conjunction with a heart team approach and surgeon experience, are imperative for the successful outcome of robotic coronary artery revascularization.
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- 2024
3. The Current Status of Minimally Invasive Conduit Harvesting for Coronary Artery Bypass Grafting
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Anderson, Devon, Kiaii, Bob, and Catrip, Jorge
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Biomedical and Clinical Sciences ,Clinical Sciences ,Pain Research ,Atherosclerosis ,Cardiovascular ,Heart Disease ,Heart Disease - Coronary Heart Disease ,5.4 Surgery ,coronary artery bypass grafting surgery ,minimally invasive ,conduit ,cardiac surgery ,Cardiovascular medicine and haematology - Abstract
The harvesting of conduits for coronary artery bypass surgery has evolved over the last decade to include endoscopic approaches to access the saphenous vein, radial artery, and internal mammary artery. These minimally invasive techniques reduce the morbidity associated with open procedures by decreasing pain and recovery time and increasing mobility post operatively. This review highlights the differences in morbidity, quality, and patency between the most common conduits that are harvested minimally invasively for coronary artery bypass grafting surgery.
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- 2024
4. Effect of lipid-lowering medications in patients with coronary artery bypass grafting surgery outcomes
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Shi, Chunxia, Zhang, Zugui, Goldhammer, Jordan, Li, David, Kiaii, Bob, Rudriguez, Victor, Boyd, Douglas, Lubarsky, David, Applegate, Richard, and Liu, Hong
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Aging ,Atherosclerosis ,Heart Disease ,Cardiovascular ,Patient Safety ,Clinical Research ,Heart Disease - Coronary Heart Disease ,Clinical Trials and Supportive Activities ,6.4 Surgery ,Evaluation of treatments and therapeutic interventions ,Good Health and Well Being ,Aged ,Cardiopulmonary Bypass ,Coronary Artery Bypass ,Humans ,Lipids ,Postoperative Complications ,Quality of Life ,Retrospective Studies ,CABG ,CPB ,Perioperative lipid-lowering drug ,Adverse events ,Outcome ,Medical Physiology ,Anesthesiology - Abstract
BackgroundIncreased life expectancy and improved medical technology allow increasing numbers of elderly patients to undergo cardiac surgery. Elderly patients may be at greater risk of postoperative morbidity and mortality. Complications can lead to worsened quality of life, shortened life expectancy and higher healthcare costs. Reducing perioperative complications, especially severe adverse events, is key to improving outcomes in patients undergoing cardiac surgery. The objective of this study is to determine whether perioperative lipid-lowering medication use is associated with a reduced risk of complications and mortality after coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB).MethodsAfter IRB approval, we reviewed charts of 9,518 patients who underwent cardiac surgery with CPB at three medical centers between July 2001 and June 2015. The relationship between perioperative lipid-lowering treatment and postoperative outcome was investigated. 3,988 patients who underwent CABG met inclusion criteria and were analyzed. Patients were divided into lipid-lowering or non-lipid-lowering treatment groups.ResultsA total of 3,988 patients were included in the final analysis. Compared to the patients without lipid-lowering medications, the patients with lipid-lowering medications had lower postoperative neurologic complications and overall mortality (P
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- 2022
5. How to implement a clinical robotic mitral valve surgery program.
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Xue, Anna, Chen, Sarah, Ranade, Alison, Smith, Kimberly, Kasten, Jeff, Catrip, Jorge, and Kiaii, Bob
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Minimally invasive ,mitral valve surgery ,robotic ,stimulation team training - Abstract
Minimally invasive, specifically, robot-assisted mitral valve surgery has evolved as a method to intervene on mitral valve disease without a median sternotomy while providing the advantages of excellent visualization and allowing for precise technical movements in a small space with the goal to decrease surgical invasiveness, post-operative pain, and hospital length of stay. As patient interest in minimally invasive cardiac procedures become more prevalent and patients seek the opportunity to undergo robotic valve surgery, institutions worldwide are exploring the potential of establishing a robotic mitral valve surgery program. While robust existing experience in open surgical mitral valve repair, careful patient selection, a dedicated team, and institution support are fundamental factors to implement a new robotic mitral valve surgery program, we believe that simulation team training prior to transitioning to live cases is also crucial and should be incorporated to establish a successful mitral valve surgery program.
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- 2022
6. Clinical and economic outcomes after sternotomy for cardiac surgery with skin closure through 2-octyl cyanoacrylate plus polymer mesh tape versus absorbable sutures plus waterproof wound dressings: a retrospective cohort study.
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Johnston, Stephen, Jang, Se, Elangovanraaj, Nivesh, Tewari, Pranjal, Chen, Brian, and Kiaii, Bob
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2-octyl cyanoacrylate ,Absorbable sutures ,Skin closure ,Sternotomy ,Bandages ,Cardiac Surgical Procedures ,Cyanoacrylates ,Humans ,Polymers ,Retrospective Studies ,Sternotomy ,Surgical Mesh ,Surgical Wound Infection ,Sutures - Abstract
BACKGROUND: To compare clinical and economic outcomes after sternotomy for cardiac surgery with skin closure through 2-octyl cyanoacrylate plus polymer mesh tape (2OPMT) versus conventional absorbable sutures plus waterproof wound dressings (CSWWD). METHODS: Retrospective study using the Premier Healthcare Database. Patients undergoing a cardiac surgery requiring sternotomy with 2OPMT or CSWWD were included. Primary outcome was 60-day cumulative incidence of diagnosis for wound complications (infection, dehiscence). Secondary outcomes were index admission hospital length of stay (LOS), total hospital-borne costs, discharge status, and 60-day cumulative incidences of inpatient readmission and reoperation. After propensity score matching, outcomes were compared between the 2OPMT and CSWWD groups using bivariate multilevel mixed-effects generalized linear models. RESULTS: Overall, 7,901 2OPMT patients and 10,775 CSWWD patients were eligible for study. After propensity score matching on 68 variables, each group comprised 5,338 patients (total study N = 10,676). The 2OPMT and CSWWD groups did not differ significantly in terms of the 60-day cumulative incidences of wound complication (3.47% vs 3.47%, p = 0.996), inpatient readmission (12.6% vs. 13.6%, p = 0.354), and reoperation (10.3% vs 10.1%, p = 0.808), as well as discharge to home versus non-home setting (77.2% vs. 75.1%), p = 0.254. However, the 2OPMT group had significantly lower LOS (9.2 days vs 10.6 days, p
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- 2022
7. Three-year outcomes of the Dissected Aorta Repair Through Stent Implantation trial
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Bozso, Sabin J., Nagendran, Jeevan, Chu, Michael W.A., Kiaii, Bob, El-Hamamsy, Ismail, Ouzounian, Maral, Forcillo, Jessica, Kempfert, Jörg, Starck, Christoph, and Moon, Michael C.
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- 2024
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8. Cardiac surgeons concerns, perceptions, and responses during the COVID-19 pandemic.
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Luc, Jessica, Ad, Niv, Nguyen, Tom, Arora, Rakesh, Balkhy, Husam, Bender, Edward, Bethencourt, Daniel, Bisleri, Gianluigi, Boyd, Douglas, Chu, Michael, de la Cruz, Kim, DeAnda, Abe, Engelman, Daniel, Farkas, Emily, Fedoruk, Lynn, Fiocco, Michael, Forcillo, Jessica, Fradet, Guy, Fremes, Stephen, Gammie, James, Geirsson, Arnar, Gerdisch, Marc, Girard, Leonard, Kaiser, Clayton, Kaneko, Tsuyoshi, Kent, William, Khabbaz, Kamal, Khoynezhad, Ali, Lee, Richard, Legare, Jean-Francois, Lehr, Eric, MacArthur, Roderick, McCarthy, Patrick, Mehall, John, Merrill, Walter, Moon, Marc, Ouzounian, Maral, Peltz, Matthias, Perrault, Louis, Preventza, Ourania, Ramchandani, Mahesh, Ramlawi, Basel, Salenger, Rawn, Sekela, Michael, Sellke, Frank, Stulak, John, Sutter, Francis, Timek, Tomasz, Whitman, Glenn, Williams, Judson, Wong, Daniel, Yanagawa, Bobby, Ye, Jian, Zeigler, Sanford, and Kiaii, Bob
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cardiovascular research ,Adult ,COVID-19 ,Decontamination ,Humans ,Pandemics ,Perception ,SARS-CoV-2 ,Surgeons - Abstract
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has had an unprecedented impact on health care and cardiac surgery. We report cardiac surgeons concerns, perceptions, and responses during the COVID-19 pandemic. METHODS: A detailed survey was sent to recruit participating adult cardiac surgery centers in North America. Data regarding cardiac surgeons perceptions and changes in practice were analyzed. RESULTS: Our study comprises 67 institutions with diverse geographic distribution across North America. Nurses were most likely to be redeployed (88%), followed by advanced care practitioners (69%), trainees (28%), and surgeons (25%). Examining surgeon concerns in regard to COVID-19, they were most worried with exposing their family to COVID-19 (81%), followed by contracting COVID-19 (68%), running out of personal protective equipment (PPE) (28%), and hospital resources (28%). In terms of PPE conservation strategies among users of N95 respirators, nearly half were recycling via decontamination with ultraviolet light (49%), followed by sterilization with heat (13%) and at home or with other modalities (13%). Reuse of N95 respirators for 1 day (22%), 1 week (21%) or 1 month (6%) was reported. There were differences in adoption of methods to conserve N95 respirators based on institutional pandemic phase and COVID-19 burden, with higher COVID-19 burden institutions more likely to resort to PPE conservation strategies. CONCLUSIONS: The present study demonstrates the impact of COVID-19 on North American cardiac surgeons. Our study should stimulate further discussions to identify optimal solutions to improve workforce preparedness for subsequent surges, as well as facilitate the navigation of future healthcare crises.
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- 2021
9. Perioperative dexmedetomidine and 5-year survival in patients undergoing cardiac surgery.
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Peng, Ke, Shen, Yue-Ping, Ying, Yao-Yu, Kiaii, Bob, Rodriguez, Victor, Boyd, Douglas, Applegate, Richard L, Lubarsky, David A, Zhang, Zugui, Xia, Zhengyuan, Feng, Xiao-Mei, Yang, Jian-Ping, Liu, Hong, and Ji, Fu-Hai
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Humans ,Postoperative Complications ,Dexmedetomidine ,Hypnotics and Sedatives ,Treatment Outcome ,Perioperative Care ,Cardiac Surgical Procedures ,Coronary Artery Bypass ,Survival Analysis ,Retrospective Studies ,Cohort Studies ,Aged ,Middle Aged ,Female ,Male ,cardiac surgery ,complications ,dexmedetomidine ,long-term survival ,postoperative outcomes ,Heart Disease ,Clinical Research ,Cardiovascular ,Clinical Sciences ,Anesthesiology - Abstract
BackgroundDexmedetomidine sedation has been associated with favourable outcomes after surgery. We aimed to assess whether perioperative dexmedetomidine use is associated with improved survival after cardiac surgery.MethodsThis retrospective cohort study included 2068 patients undergoing on-pump coronary artery bypass grafting and/or valve surgery. Among them, 1029 patients received dexmedetomidine, and 1039 patients did not. Intravenous dexmedetomidine infusion of 0.007 μg kg-1 min-1 was initiated before or immediately after cardiopulmonary bypass and lasted for < 24 h. The primary outcome was 5-year survival after cardiac surgery. The propensity scores matching (PSM), inverse probability of treatment weighting (IPTW), and overlap weighting approaches were used to minimise bias. Survival analyses were performed with Cox proportional-hazard models.ResultsThe median age was 63 yr old and the male to female ratio was 71:29 in both groups. Baseline covariates were balanced between groups after adjustment using PSM, IPTW, or overlap weighting. Patients receiving dexmedetomidine in cardiac surgical procedures had higher survival during postoperative 5 yr in unadjusted analysis (hazard ratio [HR]=0.63; 95% confidence interval [CI], 0.51-0.78; P
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- 2021
10. A Retrospective Evaluation of Endo-Aortic Balloon Occlusion Compared to External Clamping in Minimally Invasive Mitral Valve Surgery
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Balkhy, Husam H., Grossi, Eugene A., Kiaii, Bob, Murphy, Douglas, Geirsson, Arnar, Guy, Sloane, and Lewis, Clifton
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- 2024
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11. Coronary artery calcium progression after coronary artery bypass grafting surgery.
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Abazid, Rami, Romsa, Jonathan, Akincioglu, Cigdem, Warrington, James, Bureau, Yves, Vezina, William, and Kiaii, Bob
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atherosclerosis ,computed tomography angiography ,coronary artery bypass ,Atherosclerosis ,Calcium ,Coronary Angiography ,Coronary Artery Bypass ,Coronary Artery Disease ,Coronary Vessels ,Female ,Follow-Up Studies ,Humans ,Male ,Middle Aged ,Retrospective Studies ,Risk Factors ,Tomography ,X-Ray Computed - Abstract
OBJECTIVES: Accelerated atherosclerosis is a well-established phenomenon after coronary artery bypass grafting surgery (CABG). In this study, we analysed coronary artery calcium (CCS) progression after CABG. METHODS: We retrospectively measured the CCS Agatston score (AS), volume score (VS) and mass score (MS) of 39 patients before and after CABG. The annualised CCS change and annualised CCS percent change of each coronary artery, coronary artery segments proximal and distal to anastomosis were analysed. RESULTS: Mean age at the time of the surgery was 59.8±8.5 years. Follow-up period between the first and second CT scans was 6.7±2.8 (range, 1.1-12.8) years. Annualised CCS percent change (AS, VS and MS) of the coronary segments proximal-to-anastomosis did not differ from that of the non-grafted coronary arteries as follow: segments proximal-to-anastomosis: median (Q1-Q3) 12.8 (5.0-37.4), 13.7 (6.1-41.1) and 14.9 (5.4-53.7), left main coronary artery 12.6 (7.4-43.8), 22.0 (8.1-44.4) and 18.2 (7.3-57.4), non-grafted left circumflex artery: 13.5 (4.4-38.1), 10.5 (2.9-45.2) and 11.5 (7.1-47.9) and non-grafted right coronary artery: 31.4 (14.4-74.5), 25.2 (16.7-62.0) and 31.3 (23.8-85.6), respectively. Likewise, annualised percent change (AS, VS and MS) was similar between the native coronary arteries. Multivariate regression analysis showed that diabetes mellitus was the only predictor of annualised percent progression of the total CCS of >15% (HR, 8.12; 95% CI, 1.05 to 26.6; p=0.04). CONCLUSION: The CCS post-CABG did not follow an accelerated progression process. Among coronary artery disease risk factors, diabetes mellitus is the only predictor of annualised CCS percent progression of >15% post-CABG.
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- 2021
12. Measurement and prognosis of frail patients undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis.
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Hashi, Adam, Bi, Ran, Yeschin, Michelle, John-Baptiste, Ava, Li, Zhe, Dawson, Emily, Moodie, Jessica, Martin, Janet, Bagur, Rodrigo, Cheng, Davy, and Kiaii, Bob
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cardiac surgery ,epidemiology ,valvular heart disease ,vascular surgery ,Aged ,Aortic Valve Stenosis ,Frail Elderly ,Humans ,Prognosis ,Risk Factors ,Transcatheter Aortic Valve Replacement ,Treatment Outcome - Abstract
OBJECTIVES: Our objectives were to review the literature to identify frailty instruments in use for transcatheter aortic valve implantation (TAVI) recipients and synthesise prognostic data from these studies, in order to inform clinical management of frail patients undergoing TAVI. METHODS: We systematically reviewed the literature published in 2006 or later. We included studies of patients with aortic stenosis, diagnosed as frail, who underwent a TAVI procedure that reported mortality or clinical outcomes. We categorised the frailty instruments and reported on the prevalence of frailty in each study. We summarised the frequency of clinical outcomes and pooled outcomes from multiple studies. We explored heterogeneity and performed subgroup analysis, where possible. We also used Grading of Recommendations, Assessment, Development and Evaluation (GRADE) to assess the overall certainty of the estimates. RESULTS: Of 49 included studies, 21 used single-dimension measures to assess frailty, 3 used administrative data-based measures, and 25 used multidimensional measures. Prevalence of frailty ranged from 5.67% to 90.07%. Albumin was the most commonly used single-dimension frailty measure and the Fried or modified Fried phenotype were the most commonly used multidimensional measures. Meta-analyses of studies that used either the Fried or modified Fried phenotype showed a 30-day mortality of 7.86% (95% CI 5.20% to 11.70%) and a 1-year mortality of 26.91% (95% CI 21.50% to 33.11%). The GRADE system suggests very low certainty of the respective estimates. CONCLUSIONS: Frailty instruments varied across studies, leading to a wide range of frailty prevalence estimates for TAVI recipients and substantial heterogeneity. The results provide clinicians, patients and healthcare administrators, with potentially useful information on the prognosis of frail patients undergoing TAVI. This review highlights the need for standardisation of frailty measurement to promote consistency. PROSPERO REGISTRATION NUMBER: CRD42018090597.
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- 2021
13. Regional Differences in the Ghrelin-Growth Hormone Secretagogue Receptor Signalling System in Human Heart Disease.
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Luyt, Leonard, Wisenberg, Gerald, Dhanvantari, Savita, Sullivan, Rebecca, Randhawa, Varinder, Lalonde, Tyler, Yu, Tina, and Kiaii, Bob
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BACKGROUND: The hormone ghrelin and its receptor, the growth hormone secretagogue receptor (GHSR) are expressed in myocardium. GHSR binding activates signalling pathways coupled to cardiomyocyte survival and contractility. These properties have made the ghrelin-GHSR axis a candidate for a biomarker of cardiac function. The dynamics of ghrelin-GHSR are altered significantly in late stages of heart failure (HF) and cardiomyopathy, when left ventricular (LV) function is failing. We examined the relationship of GHSR with ghrelin in cardiac tissue from patients with valvular disease with no detectable changes in LV function. METHODS: Biopsy samples from the left ventricle and left atrium were obtained from 25 patients with valvular disease (of whom 13 also had coronary artery disease) and preserved LV ejection fraction, and compared to control samples obtained via autopsy. Using quantitative confocal fluorescence microscopy, levels of GHSR were determined using [Dpr3(n-octanoyl),Lys19(sulfo-Cy5)]ghrelin(1-19), and immunofluorescence determined ghrelin, the heart failure marker natriuretic peptide type-B (BNP), and contractility marker sarcoplasmic reticulum ATPase pump (SERCA2a). RESULTS: A positive correlation between GHSR and ghrelin was apparent in only diseased tissue. Ghrelin and BNP significantly correlated in the left ventricle and strongly colocalized to the same intracellular compartment in diseased and control tissue. GHSR, ghrelin, and BNP all strongly and significantly correlated with SERCA2a in the left ventricle of diseased tissue only. CONCLUSIONS: Our results suggest that the dynamics of the myocardial ghrelin-GHSR axis is altered in cardiovascular disease in the absence of measurable changes in heart function, and might accompany a regional shift in endocrine programming.
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- 2021
14. Hiatal hernia after robotic-assisted coronary artery bypass graft surgery.
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Abazid, Rami, Khatami, Alireza, Romsa, Jonathan, Warrington, James, Akincioglu, Cigdem, Stodilka, Robert, Fox, Stephanie, Vezina, William, and Kiaii, Bob
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Hiatal hernia (HH) ,coronary artery bypass grafting (CABG) ,robotic-assisted - Abstract
BACKGROUND: The aim of the present study is to determine the incidence/progression of hiatal hernia (HH) after robotic-assisted coronary artery bypass grafting (RA-CABG) surgery. METHODS: We reviewed the pre- and post-operative computed tomography (CT) of 491 patients who underwent RA-CABG between 2000 and 2017. Post-operative CT was acquired prospectively in a research protocol. CT was reviewed to assess the presence and the size of HH. RESULTS: We found 444/491 (90.4%) had pre-operative CT, while 201/491 (40.9%) had post-operative CT. In total, 155/491 (31.6%) had both pre- and long-term post-operative CT with a mean follow-up of 6.2 (±3.5) years. HH was more prevalent on post-operative CT, 64/155 (41.3%) compared to pre-operative CT, 44/155 (28.4%), P
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- 2021
15. Outcomes of Surgical Bioprosthetic Aortic Valve Replacement in Patients Aged ≤65 and >65 Years
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Kiaii, Bob B., Moront, Michael G., Patel, Himanshu J., Ruel, Marc, Bensari, Feryel Nawel, Kress, David C., Liu, Fang, Klautz, Robert J.M., and Sabik, Joseph F., III
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- 2023
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16. Abstract 15827: Impact of Harvesting Techniques on Coronary Bypass Conduit Endothelial Cells and Collagen Exposure Using Ligand-Based Targeting
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Bahatyrevich, Nataliya, Ramasubramanian, Lalithasri, Hao, Dake, Loll, Emma, Lopez, Juan-Maria G, Kwong, Mimmie, Wozniak, Curtis J, Evans, Sabrina A, CATRIP, JORGE, Kiaii, Bob, and Wang, Aijun
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- 2023
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17. Performance of administrative database frailty instruments in predicting clinical outcomes and cost for patients undergoing transcatheter aortic valve implantation: a historical cohort study
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Li, Zhe, Wijeysundera, Harindra C., Bagur, Rodrigo, Cheng, Davy, Martin, Janet, Kiaii, Bob, Qiu, Feng, Fang, Jiming, and John-Baptiste, Ava
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- 2023
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18. Cost-Effectiveness Analysis of Frailty Assessment in Older Patients Undergoing Coronary Artery Bypass Grafting Surgery.
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Li, Zhe, Habbous, Steven, Thain, Jenny, Hall, Daniel, Nagpal, A, Bagur, Rodrigo, John-Baptiste, Ava, and Kiaii, Bob
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Aged ,Aged ,80 and over ,Coronary Artery Bypass ,Coronary Artery Disease ,Cost-Benefit Analysis ,Decision Trees ,Frailty ,Geriatric Assessment ,Humans ,Markov Chains ,Perioperative Care ,Quality-Adjusted Life Years - Abstract
BACKGROUND: In perioperative settings, frailty assessment has been shown to reduce mortality. This study examined the cost effectiveness of frailty assessment among patients aged 65 with coronary artery disease under consideration for coronary artery bypass grafting surgery. METHODS: A combined decision tree and Markov model was developed to estimate costs and quality-adjusted life years (QALYs) over a 21-year time horizon. Clinical parameters were obtained from published literature. Utilities were derived from the literature and the Canadian Community Health Survey. Costs were obtained from the Ontario fee schedule and published literature. Sensitivity and scenario analyses were conducted to assess the robustness of the results. Expected value of perfect information (EVPI) analysis was conducted to estimate the value of further research. RESULTS: The frailty assessment initiative had a lower average cost than no frailty assessment ($19,567 compared with $20,062). QALYs with frailty assessment were 0.47 years more than with no frailty assessment. Thus, frailty assessment was dominant compared with no frailty assessment. Results were robust to changes in the input parameters. At a willingness to pay (WTP) threshold of $50,000/QALY, there was 100% probability of frailty assessment being cost-effective, and the EVPI per patient was $0. Scenario and sensitivity analysis showed frailty screening remained cost effective when changing the cohort average age, removing health benefits for nonfrail patients, and using subjective judgement to modify effectiveness parameters. CONCLUSIONS: Frailty assessment may be good value for money. However, limited availability of geriatric consultation services, may hinder implementation. Thus, the estimated benefits of frailty screening may not be achievable in practice.
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- 2020
19. Hybrid Coronary Revascularization Versus Off-Pump Coronary Artery Bypass Grafting: Comparative Effectiveness Analysis With Long-Term Follow-up.
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Hage, Ali, Giambruno, Vincenzo, Jones, Philip, Chu, Michael, Fox, Stephanie, Teefy, Patrick, Lavi, Shahar, Bainbridge, Daniel, Harle, Christopher, Iglesias, Ivan, Dobkowski, Woijtecj, and Kiaii, Bob
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cardiac surgery ,coronary artery bypass graft surgery ,hybrid ,percutaneous coronary intervention ,robotic‐assisted CABG ,Aged ,Combined Modality Therapy ,Coronary Artery Bypass ,Coronary Artery Bypass ,Off-Pump ,Coronary Artery Disease ,Female ,Follow-Up Studies ,Humans ,Male ,Middle Aged ,Percutaneous Coronary Intervention ,Retrospective Studies ,Robotic Surgical Procedures ,Time Factors ,Treatment Outcome - Abstract
Background Hybrid coronary revascularization (HCR) involves the integration of coronary artery bypass grafting (CABG) and percutaneous coronary intervention to treat multivessel coronary artery disease. Our objective was to perform a comparative analysis with long-term follow-up between HCR and conventional off-pump CABG. Methods and Results We compared all double off-pump CABG (n=216) and HCR (n=147; robotic-assisted minimally invasive direct CABG of the left internal thoracic artery to the left anterior descending artery and percutaneous coronary intervention to one of the non-left anterior descending vessels) performed at a single institution between March 2004 and November 2015. To adjust for the selection bias of receiving either off-pump CABG or HCR, we performed a propensity score analysis using inverse-probability weighting. Both groups had similar results in terms of re-exploration for bleeding, perioperative myocardial infarction, stroke, blood transfusion, in-hospital mortality, and intensive care unit length of stay. HCR was associated with a higher in-hospital reintervention rate (CABG 0% versus HCR 3.4%; P=0.03), lower prolonged mechanical ventilation (>24 hours) rate (4% versus 0.7%; P=0.02), and shorter hospital length of stay (8.1±5.8 versus 4.5±2.1 days; P
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- 2019
20. Emergent Percutaneous Rotational Atherectomy to Bailout Surgical Transapical Aortic Valve Implantation: A Successful Case of Heart Team Turnaround.
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Teefy, Patrick, Choudhury, Tawfiq, Bakar, Shahrukh, and Kiaii, Bob
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Aged ,80 and over ,Aortic Valve ,Aortic Valve Stenosis ,Atherectomy ,Coronary ,Coronary Angiography ,Humans ,Male ,Percutaneous Coronary Intervention ,Tomography ,X-Ray Computed ,Transcatheter Aortic Valve Replacement - Abstract
Transcatheter aortic valve implantation (TAVI) is an established treatment for severe aortic stenosis (AS) in patients with elevated surgical risk. Concomitant coronary artery disease affects 55-70% of patients with severe AS. Percutaneous coronary intervention in patients with TAVI can be challenging. We report a case of acute coronary obstruction immediately following transapical TAVI deployment requiring emergent rotational atherectomy.
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- 2019
21. Dynamics of the Ghrelin/Growth Hormone Secretagogue Receptor System in the Human Heart Before and After Cardiac Transplantation.
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Sullivan, Rebecca, Randhawa, Varinder, Stokes, Anne, Wu, Derek, Lalonde, Tyler, Luyt, Leonard, Wisenberg, Gerald, Dhanvantari, Savita, and Kiaii, Bob
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Currently, the early preclinical detection of left ventricular dysfunction is difficult because biomarkers are not specific for the cardiomyopathic process. The underlying molecular mechanisms leading to heart failure remain elusive, highlighting the need for identification of cardiac-specific markers. The growth hormone secretagogue receptor (GHSR) and its ligand ghrelin are present in cardiac tissue and are known to contribute to myocardial energetics. Here, we examined tissue ghrelin-GHSR levels as specific markers of cardiac dysfunction in patients who underwent cardiac transplantation. Samples of cardiac tissue were obtained from 10 patients undergoing cardiac transplant at the time of organ harvesting and during serial posttransplant biopsies. Quantitative fluorescence microscopy using a fluorescent ghrelin analog was used to measure levels of GHSR, and immunofluorescence was used to measure levels of ghrelin, B-type natriuretic peptide (BNP), and tissue markers of cardiomyocyte contractility and growth. GHSR and ghrelin expression levels were highly variable in the explanted heart, less in the grafted heart biopsies. GHSR and ghrelin were strongly positively correlated, and both markers were negatively correlated with left ventricular ejection fraction. Ghrelin had stronger positive correlations than BNP with the signaling markers for contractility and growth. These data suggest that GHSR-ghrelin have potential use as an integrated marker of cardiac dysfunction. Interestingly, tissue ghrelin appeared to be a more sensitive indicator than BNP to the biochemical processes that are characteristic of heart failure. This work allows for further use of ghrelin-GHSR to interrogate cardiac-specific biochemical mechanisms in preclinical stages of heart failure (HF).
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- 2019
22. Frailty in patients undergoing transcatheter aortic valve implantation: a protocol for a systematic review.
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Li, Zhe, Dawson, Emily, Moodie, Jessica, Martin, Janet, Bagur, Rodrigo, Cheng, Davy, John-Baptiste, Ava, and Kiaii, Bob
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aortic stenosis ,frailty ,prognosis ,protocol ,systematic review ,transcathter aortic valve implantation ,Aged ,Aortic Valve Stenosis ,Frail Elderly ,Frailty ,Humans ,Quality of Life ,Transcatheter Aortic Valve Replacement ,Treatment Outcome ,Systematic Reviews as Topic - Abstract
INTRODUCTION: Aortic stenosis is a significant cause of morbidity and mortality in older patients. The advent of transcatheter aortic valve implantation (TAVI) offers an alternative to surgical aortic valve replacement for patients with severe symptomatic aortic stenosis who are at high or intermediate risk of adverse events. Existing evidence highlights the importance of frailty as a predictor of poor outcomes post-TAVI. The objective of this study is to review the operationalisation of frailty instruments for TAVI recipients and determine clinical outcomes and the change in quality of life in frail patients undergoing TAVI. METHODS AND ANALYSIS: Methods are reported according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols 2015 checklist. We will search relevant databases to identify published, completed but unpublished and ongoing studies. We will include studies of patients with aortic stenosis, diagnosed as frail and who underwent a TAVI procedure that report mortality, clinical outcomes or health-related quality of life. Retrospective or prospective cohort studies, randomised controlled trials and non-randomised controlled trials will be eligible for inclusion. Two researchers will independently screen articles for inclusion, with disagreements resolved by a third reviewer. One researcher will extract data with audit by a second researcher. The risk of bias in studies will be evaluated using the Quality in Prognosis Studies tool. Meta-analysis of mortality, survival curve and the change in quality of life will be performed if appropriate. Subgroup analysis, sensitivity analysis and meta-regression will be performed if necessary. ETHICS AND DISSEMINATION: Due to the nature of this study, no ethical issues are foreseen. We will disseminate the results of our systematic review through a peer-reviewed journal. TRIAL REGISTRATION NUMBER: CRD42018090597.
- Published
- 2019
23. Parsimonious machine learning models to predict resource use in cardiac surgery across a statewide collaborative
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Benharash, Peyman, Shemin, Richard J., Satou, Nancy, Nguyen, Tom, Clary, Carolyn, Madani, Michael, Higgins, Jill, Steltzner, Dawna, Kiaii, Bob, Young, J. Nilas, Behan, Kathleen, Houston, Heather, Matsumoto, Cindi, Sun, Jack C., Flavin, Lisha, Fopiano, Patria, Cabrera, Maricel, Khaki, Rakan, Washabaugh, Polly, Verma, Arjun, Sanaiha, Yas, Hadaya, Joseph, Maltagliati, Anthony Jason, Tran, Zachary, and Ramezani, Ramin
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- 2022
- Full Text
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24. Why the categorization of indexed effective orifice area is not justified for the classification of prosthesis–patient mismatch
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Vriesendorp, Michiel D., Deeb, G. Michael, Reardon, Michael J., Kiaii, Bob, Bapat, Vinayak, Labrousse, Louis, Rao, Vivek, Sabik, Joseph F., III, Gearhart, Elizabeth, and Klautz, Robert J.M.
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- 2022
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25. Clinical and economic outcomes after sternotomy for cardiac surgery with skin closure through 2-octyl cyanoacrylate plus polymer mesh tape versus absorbable sutures plus waterproof wound dressings: a retrospective cohort study
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Kiaii, Bob, Johnston, Stephen S., Jang, Se Ryeong, Elangovanraaj, Nivesh, Tewari, Pranjal, and Chen, Brian Po-Han
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- 2022
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26. Robotic Cardiac Valvular Surgery
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Kiaii, Bob, Cheng, Davy C.H., editor, Martin, Janet, editor, and David, Tirone, editor
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- 2021
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27. Robotic Coronary Artery Revascularization
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Kiaii, Bob, Cheng, Davy C.H., editor, Martin, Janet, editor, and David, Tirone, editor
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- 2021
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28. Cardiac-Referenced Leukocyte Telomere Length and Outcomes After Cardiovascular Surgery.
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Chu, Michael, Pickering, J, Yin, Hao, Akawi, Oula, Fox, Stephanie, Li, Fuyan, ONeil, Caroline, Balint, Brittany, Arpino, John-Michael, Watson, Alanna, Wong, Jorge, Guo, Linrui, Quantz, MacKenzie, Nagpal, A, and Kiaii, Bob
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CI ,confidence interval ,HR ,hazard ratio ,ICU ,intensive care unit ,OR ,odds ratio ,PCR ,polymerase chain reaction ,TL ,telomere length ,atrium ,bp ,base pair ,risk ,surgery ,telomere shortening ,ΔTLRA-L ,right atrium-leukocyte TL difference - Abstract
Leukocyte telomere shortening reflects stress burdens and has been associated with cardiac events. However, the patient-specific clinical value of telomere assessment remains unknown. Moreover, telomere shortening cannot be inferred from a single telomere length assessment. The authors investigated and developed a novel strategy for gauging leukocyte telomere shortening using autologous cardiac atrial referencing. Using multitissue assessments from 163 patients who underwent cardiovascular surgery, we determined that the cardiac atrium-leukocyte telomere length difference predicted post-operative complexity. This constituted the first evidence that a single-time assessment of telomere dynamics might be salient to acute cardiac care.
- Published
- 2018
29. Clinical outcomes of a combined transcatheter and minimally invasive atrial septal defect repair program using a Heart Team approach.
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Bakar, Shahrukh, Burns, Daniel, Diamantouros, Pantelis, Sridhar, Kumar, Chu, Michael, and Kiaii, Bob
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Atrial Septal defect ,Minimally invasive ,Percutaneous ,Transcatheter ,Adult ,Aged ,Cardiac Catheterization ,Female ,Heart Septal Defects ,Atrial ,Humans ,Intraoperative Complications ,Length of Stay ,Male ,Middle Aged ,Minimally Invasive Surgical Procedures ,Patient Care Team ,Retrospective Studies ,Treatment Outcome ,Young Adult - Abstract
BACKGROUND: Contemporary transcatheter and minimally invasive approaches allow for improved cosmesis and eliminate sternotomy; however, access to a Heart Team approach to minimally invasive atrial septal defect (ASD) repair remains limited in Canada. METHODS: Retrospective chart review of all minimally invasive atrial septal defect repairs performed between 2009 and 2017 at a quaternary cardiac care centre were included. We compared residual shunt, functional status, periprocedural complications, and hospital lengths-of-stay between patients undergoing transcatheter and minimally invasive endoscopic ASD repair. RESULTS: Between 2009 and 2017, 61 consecutive patients underwent ASD repair at a single centre: 28 patients underwent transcatheter closure (64.3% female; median age 57, interquartile range 43-70.5) and 33 patients underwent minimally invasive endoscopic repair (72.7% female; median age 37, interquartile range 24-50). Patient demographics were similar between the two groups with the exception of transcatheter patients having smaller defect size (1.65 cm versus 2.35 cm, p = 0.002). Procedural success was 93% (26/28) and 100% (33/33) for transcatheter and minimally invasive groups (p = 0.21), respectively. Periprocedural complications were similarly low between the two groups with the exception of longer hospital length-of-stay in the surgical patients (5 days vs 1 day, p
- Published
- 2018
30. Abstract 15059: Effects of Cigarette Smoke on Inflammation and Atrial Fibrillation
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Sirish, Padmini, Diloretto, Daphne, Kiaii, Bob, and Chiamvimonvat, Nipavan
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- 2022
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31. Abstract 14554: Novel Upstream Targets for Atrial Fibrillation
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Sirish, Padmini, Yang, Jun, Datta, Esha, Ballal, Aditya, Srivatsa, Uma N, Kiaii, Bob, Izu, Leighton, Hammock, Bruce D, and Chiamvimonvat, Nipavan
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- 2022
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32. Comparison of outcomes of root replacement procedures and supracoronary techniques for surgical repair of acute aortic dissection.
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Valdis, Matthew, Adams, Corey, Chu, Michael, Guo, Linrui, and Kiaii, Bob
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Aftercare ,Aged ,Aortic Dissection ,Aortic Diseases ,Female ,Humans ,Male ,Middle Aged ,Ontario ,Outcome and Process Assessment ,Health Care ,Postoperative Complications ,Reoperation ,Retrospective Studies ,Vascular Grafting ,Vascular Surgical Procedures - Abstract
BACKGROUND: Surgical approach to type A acute aortic dissection (AADA) is usually dictated by the presenting anatomy. We compared long-term outcomes of AADA repaired with a root replacement versus a supracoronary tube graft, regardless of the proximal extent of the intimal tear. METHODS: A single-centre, retrospective cohort of consecutive patients undergoing repair of AADA between December 1999 and March 2012 were stratified based on the proximal surgical procedure performed: supracoronary tube graft or root replacement. Imaging, chart reviews and clinical follow-ups were analyzed to identify the presenting anatomy and clinical outcomes. RESULTS: We included the cases of 75 patients in our analysis: 54 received a supracoronary tube graft and 21 received a root replacement. The proximal tear was identified below the sinotubular junction in all patients in the root group and in 61% of patients in the supracoronary group. We detected no differences between the groups for in-hospital mortality, length of stay, or complications. However, the root group had significantly increased renal failure (0% v. 9.5%, p = 0.018), cardiopulmonary bypass time (198.4 ± 80.0 min v. 316.5 ± 102.5 min, p < 0.001), cross-clamp time (91.6 ± 34.9 min v. 191.3 ± 52.8 min, p < 0.001), duration of surgery (457.5 ± 129.9 min v. 611.6 ± 197.8 min, p < 0.001), and platelet transfusions (8.1 ± 7.6 v. 12.8 ± 8.7 units, p = 0.021) than the supracoronary group. Long-term follow-up demonstrated a greater incidence of 2+ aortic regurgitation among patients in the supracoronary group than the root group (29.7% v. 0.0%, p = 0.006); however, there was no difference between the groups in symptoms or reoperation. CONCLUSION: In AADA, aortic root replacement involves a longer procedure with increased risk of early renal impairment. Long-term follow-up identified significantly more aortic regurgitation and root dilation in the supracoronary group than the root group, with a trend toward worse long-term survival. However, we found no difference between the groups in mortality, reoperation or New York Heart Association class.
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- 2017
33. Higher-risk mitral valve operations after previous sternotomy: endoscopic, minimally invasive approach improves patient outcomes.
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Losenno, Katie, Jones, Philip, Valdis, Matthew, Fox, Stephanie, Chu, Michael, and Kiaii, Bob
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Aged ,Female ,Humans ,Male ,Middle Aged ,Mitral Valve Annuloplasty ,Outcome and Process Assessment ,Health Care ,Postoperative Complications ,Reoperation ,Retrospective Studies ,Sternotomy ,Thoracoscopy - Abstract
BACKGROUND: Reoperative mitral valve (MV) surgery is associated with significant morbidity and mortality; however, endoscopic minimally invasive surgical techniques may preserve the surgical benefits of conventional mitral operations while potentially reducing perioperative risk and length of stay (LOS) in hospital. METHODS: We compared the outcomes of consecutive patients who underwent reoperative MV surgery between 2000 and 2014 using a minimally invasive endoscopic approach (MINI) with those of patients who underwent a conventional sternotomy (STERN). The primary outcome was in-hospital/30-day mortality. Secondary outcomes included blood product transfusion, LOS in hospital and in the intensive care unit (ICU), and postoperative complications. RESULTS: We included 132 patients in our study: 40 (mean age 68 ± 14 yr, 70% men) underwent MINI and 92 (62 ± 13 yr, 40% men) underwent STERN. The MINI group had significantly more comorbidities than the STERN group. While there were no significant differences in complications, all point estimates suggested lower mortality and morbidity in the MINI than the STERN group (in-hospital/ 30-day mortality 5% v. 11%, p = 0.35; composite any of 10 complications 28% v. 41%, p = 0.13). Individual complication rates were similar between the MINI and STERN groups, except for intra-aortic balloon pump requirement (IABP; 0% v. 12%, p = 0.034). MINI significantly reduced the need for any blood transfusion (68% v. 84%, p = 0.036) or packed red blood cells (63% v. 79%, p = 0.042), fresh frozen plasma (35% v. 59%, p = 0.012) and platelets (20% v. 40%, p = 0.024). It also significantly reduced median hospital LOS (8 v. 12 d, p = 0.014). An exploratory propensity score analysis similarly demonstrated a significantly reduced need for IABP (p < 0.001) and a shorter mean LOS in the ICU (p = 0.046) and in hospital (p = 0.047) in the MINI group. CONCLUSION: A MINI approach for reoperative MV surgery reduces blood product utilization and hospital LOS. Possible clinically relevant differences in perioperative complications require assessment in randomized clinical trials.
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- 2016
34. Complete 2-Year Results Confirm Bayesian Analysis of the SURTAVI Trial
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Sorajja, Paul, Sun, Benjamin, Agarwal, Himanshu, Langdon, Thomas, den Heijer, Peter, Bentala, Mohamed, O’Hair, Daniel, Bajwa, Tanvir, Byrne, Timothy, Caskey, Michael, Paulus, Basil, Garrett, Edward, Jr., Stoler, Robert, Hebeler, Robert, Popma, Jeffrey J., Khabbaz, Kamal, Lim, David Scott, Bladergroen, Mark, Fail, Peter, Feinberg, Edgar, II, Rinaldi, Michael, Skipper, Eric, Chawla, Atul, Hockmuth, David, Makkar, Raj, Cheng, Wen, Kodali, Susheel, George, Isaac, Aji, Janah, Bowen, Frank, Schreiber, Theodore, Henry, Scott, Hengstenberg, Christian, Bleiziffer, Sabine, Harrison, J. Kevin, Hughes, Chad, Joye, James, Gaudiani, Vincent, Babaliaros, Vasilis, Thourani, Vinod, van Mieghem, Nicolas, Kappetein, A. Pieter, Dauerman, Harold, Schmoker, Joseph, Skelding, Kimberly, Casale, Alfred, Kovac, Jan, Spyt, Tomasz, Seshiah, Puvi, Smith, J. Michael, McKay, Raymond, Hagberg, Robert, Matthews, Ray, Starnes, Vaughn, O’Neill, William, Paone, Gaetano, Hernandez García, Jose Maria, Such, Miguel, Morís de la Tassa, Cesar, Llosa Cortina, Juan Carlos, Windecker, Stephan, Carrel, Thierry, Whisenant, Brian, Doty, John, Resar, Jon, Conte, John, Aharonian, Vicken, Pfeffer, Thomas, Rück, Andreas, Corbascio, Matthias, Blackman, Daniel, Kaul, Pankaj, Kliger, Chad, Brinster, Derek, Teefy, Patrick, Kiaii, Bob, Leya, Ferdinand, Bakhos, Mamdouh, Sandhu, Gurpreet, Pochettino, Alberto, Piazza, Nicolo, de Varennes, Benoit, van Boven, Ad, Boonstra, Piet, Waksman, Ron, Bafi, Ammar, Asgar, Anita, Cartier, Raymond, Kipperman, Robert, Brown, John, Lin, Lang, Rovin, Joshua, Sharma, Samin, Adams, David, Katz, Stanley, Hartman, Alan, Al-Jilaihawi, Hasanian, Williams, Mathew, Crestanello, Juan, Lilly, Scott, Ghani, Mohammad, Bodenhamer, Robert Mark, Rajagopal, Vivek, Kauten, James, Mumtaz, Mumbashir, Bachinsky, Williams, Nickenig, Georg, Welz, Armin, Søndergaard, Lars, Olsen, Peter Skov, Yakubov, Steven, Watson, Daniel, Chhatriwalla, Adnan, Allen, Keith, Teirstein, Paul, Tyner, Jeffrey, Mahoney, Paul, Newton, Joseph, Merhi, William, Keiser, John, Yeung, Alan, Miller, Craig, ten Berg, Jurriën, Heijmen, Robin, Petrossian, George, Robinson, Newell, Brecker, Stephen, Jahangiri, Marjan, Davis, Thomas, Batra, Sanjay, Hermiller, James, Heimansohn, David, Radhakrishnan, Sam, Fremes, Stephen, Maini, Brijeshwar, Bethea, Brian, Brown, David, Ryan, William, Reardon, Michael, Kleiman, Neal, Spies, Christian, Lau, Jeffrey, Herrmann, Howard, Bavaria, Joseph, Horlick, Eric, Feindel, Chris, Neumann, Franz-Josef, Beyersdorf, Friedhelm, Binder, Roland, Maisano, Francesco, Costa, Marco, Markowitz, Alan, Tadros, Peter, Zorn, George, III, de Marchena, Eduardo, Salerno, Tomas, Chetcuti, Stanley, Deeb, G. Michael, Labinz, Marino, Ruel, Marc, Sup Lee, Joon, Gleason, Thomas, Ling, Frederick, Knight, Peter, Robbins, Mark, Ball, Stephen, Giacomini, John, Burdon, Thomas, Applegate, Robert, Kon, Neal, Schwartz, Richard, Schubach, Scott, Forrest, John, Mangi, Abeel, Van Mieghem, Nicolas M., Yakubov, Steven J., Serruys, Patrick W., Mumtaz, Mubashir, Gada, Hemal, Kleiman, Neal S., Oh, Jae K., Kappetein, Arie Pieter, Chang, Yanping, Mugglin, Andrew S., and Reardon, Michael J.
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- 2020
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35. Comparison of isoflurane and sevoflurane in cardiac surgery: a randomized non-inferiority comparative effectiveness trial.
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Jones, Philip, Bainbridge, Daniel, Chu, Michael, Fernandes, Philip, Fox, Stephanie, Iglesias, Ivan, Lavi, Ronit, Murkin, John, and Kiaii, Bob
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Adult ,Aged ,Anesthetics ,Inhalation ,Cardiac Surgical Procedures ,Cardiotonic Agents ,Comparative Effectiveness Research ,Coronary Artery Bypass ,Critical Care ,Female ,Humans ,Isoflurane ,Kaplan-Meier Estimate ,Length of Stay ,Male ,Methyl Ethers ,Middle Aged ,Patient Readmission ,Renal Dialysis ,Sevoflurane ,Treatment Outcome ,Vasoconstrictor Agents - Abstract
PURPOSE: Volatile anesthetics possess cardioprotective properties, but it is unknown if the cardioprotective effects extend equally to all members of the class. Although sevoflurane is a relatively newer anesthetic than isoflurane, its introduction into practice was not preceded by a head-to-head comparison with isoflurane in a trial focusing on clinically important outcomes. Our objective was to determine whether sevoflurane was non-inferior to isoflurane on a clinically important primary outcome in a heterogeneous group of adults undergoing cardiac surgery. METHODS: This was a pragmatic randomized non-inferiority comparative effectiveness clinical trial in 464 adults having coronary artery bypass graft and/or single valve surgery during November 2011 to March 2014. The intervention was maintenance of anesthesia with sevoflurane (n = 231) or isoflurane (n = 233) administered at a dose of 0.5-2.0 MAC throughout the entire operation. All caregivers were blinded except for the anesthesiologist and perfusionist. The primary outcome was a composite of intensive care unit (ICU) length of stay ≥ 48 hr and all-cause 30-day mortality. We hypothesized that sevoflurane would be non-inferior to isoflurane (non-inferiority margin < 10% based on an expected event rate of 25%). Secondary outcomes included prolonged ICU stay, 30- and 365-day all-cause mortality, inotrope or vasopressor usage, new-onset hemodialysis or atrial fibrillation, stroke, and readmission to the ICU. RESULTS: No losses to follow-up occurred. The primary outcome occurred in 25% of sevoflurane patients and 30% of isoflurane patients (absolute difference, -5.4%; one-sided 95% confidence interval, 1.4), thus non-inferiority was declared. Sevoflurane was not superior to isoflurane for the primary outcome (P = 0.21) or for any secondary outcomes. CONCLUSION: Sevoflurane is non-inferior to isoflurane on a composite outcome of prolonged ICU stay and all-cause 30-day mortality. Sevoflurane is not superior to isoflurane on any other of the clinically important outcomes. This trial was registered at clinicaltrials.gov; NCT01477151.
- Published
- 2016
36. Transcatheter Aortic Valve Implantation With or Without Preimplantation Balloon Aortic Valvuloplasty: A Systematic Review and Meta-Analysis.
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Bagur, Rodrigo, Kwok, Chun, Nombela-Franco, Luis, Ludman, Peter, de Belder, Mark, Sponga, Sandro, Gunning, Mark, Nolan, James, Diamantouros, Pantelis, Teefy, Patrick, Chu, Michael, Mamas, Mamas, and Kiaii, Bob
- Subjects
aortic stenosis ,aortic valve replacement ,balloon aortic valvuloplasty ,transcutaneous aortic valve implantation ,transfemoral aortic valve implantation ,Aged ,80 and over ,Aortic Valve ,Aortic Valve Stenosis ,Balloon Valvuloplasty ,Epidemiologic Methods ,Female ,Hospital Mortality ,Humans ,Male ,Transcatheter Aortic Valve Replacement ,Treatment Outcome - Abstract
BACKGROUND: Preimplantation balloon aortic valvuloplasty (BAV) is considered a routine procedure during transcatheter aortic valve implantation (TAVI) to facilitate prosthesis implantation and expansion; however, it has been speculated that fewer embolic events and/or less hemodynamic instability may occur if TAVI is performed without preimplantation BAV. The aim of this study was to systematically review the clinical outcomes associated with TAVI undertaken without preimplantation BAV. METHODS AND RESULTS: We conducted a search of Medline and Embase to identify studies that evaluated patients who underwent TAVI with or without preimplantation BAV for predilation. Pooled analysis and random-effects meta-analyses were used to estimate the rate and risk of adverse outcomes. Sixteen studies involving 1395 patients (674 with and 721 without preimplantation BAV) fulfilled the inclusion criteria. Crude device success was achieved in 94% (1311 of 1395), and 30-day all-cause mortality occurred in 6% (72 of 1282) of patients. Meta-analyses evaluating outcomes of strategies with and without preimplantation BAV showed no statistically significant differences in terms of mortality (relative risk [RR] 0.61, 95% CI 0.32-1.14, P=0.12), safety composite end point (RR 0.85, 95% CI 0.62-1.18, P=0.34), moderate to severe paravalvular leaks (RR 0.68, 95% CI 0.23-1.99, P=0.48), need for postdilation (RR 0.86, 95% CI 0.66-1.13, P=0.58), stroke and/or transient ischemic attack (RR 0.72, 95% CI 0.30-1.71, P=0.45), and permanent pacemaker implantation (RR 0.80, 95% CI 0.49-1.30, P=0.37). CONCLUSIONS: Our analysis suggests that TAVI procedures with or without preimplantation BAV were associated with similar outcomes for a number of clinically relevant end points. Further studies including a large number of patients are needed to ascertain the impact of TAVI without preimplantation BAV as a standard practice.
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- 2016
37. Robotic coronary artery surgical revascularization
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Kiaii, Bob, additional, Giambruno, Vincenzo, additional, Chu, Michael W. A., additional, Sutter, Francis P., additional, and Wertan, Mary Ann C., additional
- Published
- 2021
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38. Dissected Aorta Repair Through Stent Implantation trial: Canadian results
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Bozso, Sabin J., Nagendran, Jeevan, MacArthur, Roderick G.G., Chu, Michael W.A., Kiaii, Bob, El-Hamamsy, Ismail, Cartier, Raymond, Shahriari, Ali, and Moon, Michael C.
- Published
- 2019
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39. Robotic Coronary Artery Revascularization
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Kiaii, Bob, primary
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- 2020
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40. Robotic Cardiac Valvular Surgery
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Kiaii, Bob, primary
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- 2020
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41. Clinical outcomes of minimally invasive endoscopic and conventional sternotomy approaches for atrial septal defect repair.
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Chu, Michael, Losenno, Katie, Fox, Stephanie, Adams, Corey, Al-Habib, Hamad, Guo, Ray, Menkis, Alan, and Kiaii, Bob
- Subjects
Adult ,Aged ,Female ,Heart Septal Defects ,Atrial ,Hospital Mortality ,Humans ,Length of Stay ,Male ,Middle Aged ,Postoperative Complications ,Retrospective Studies ,Sternotomy ,Thoracoscopy ,Thoracotomy ,Treatment Outcome - Abstract
BACKGROUND: Concerns remain that minimally invasive atrial septal defect (ASD) repair may compromise patient outcomes. We compared clinical outcomes of adult patients undergoing ASD repair via a minimally invasive endoscopic approach versus a gold standard sternotomy. METHODS: We retrospectively reviewed the clinical outcomes of consecutive patients who underwent ASD patch repair at our institution between 2002 and 2012. We compared in-hospital/30-day mortality, postoperative complications, length of stay in hospital and in the intensive care unit and blood product requirements between patients who underwent right mini-thoracotomy (MT) and those who underwent conventional sternotomy. RESULTS: During the study period, 73 consecutive patients underwent ASD patch repair at our institution: 51 (age 47 ± 16 yr, 66.7% women) in the MT group and 22 (age 46 ± 21 yr, 59.1% women) in the sternotomy group. In-hospital mortality was similar between the 2 groups (MT 0% v. sternotomy 4.5%, p = 0.30). There were no significant differences in any postoperative complications or blood product requirements. No patients in the MT group suffered stroke, retrograde aortic dissection or leg ischemia. Mean intensive care unit (MT 1.2 ± 1.2 d v. sternotomy 1.7 ± 2.2 d, p = 0.26) and hospital length of stays (MT 5.1 ± 2.2 d v. sternotomy 6.3 ± 3.6 d, p = 0.17) were similar between the groups; however, there was a trend toward fewer patients requiring prolonged hospital stays (> 10 d) in the MT group (3.9% v. 18.2%, p = 0.06). CONCLUSION: Repair of ostium secundum and sinus venosus ASD can be performed safely via MT endoscopic approach with similar outcomes as sternotomy. Patient preference for a more cosmetically appealing incision may be considered without concern of compromised outcomes.
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- 2014
42. Quality of Life 5 Years Following Transfemoral TAVR or SAVR in Intermediate Risk Patients.
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Kleiman, Neal S., Van Mieghem, Nicolas M., Reardon, Michael J., Gada, Hemal, Mumtaz, Mubashir, Olsen, Peter Skov, Heiser, John, Merhi, William, Chetcuti, Stanley, Deeb, G. Michael, Chawla, Atul, Kiaii, Bob, Teefy, Patrick, Chu, Michael W.A., Yakubov, Steven J., Windecker, Stephan, Althouse, Andrew D., and Baron, Suzanne J.
- Abstract
Symptomatic patients with severe aortic stenosis (AS) at high risk for surgical aortic valve replacement (SAVR) sustain comparable improvements in health status over 5 years after transcatheter aortic valve replacement (TAVR) or SAVR. Whether a similar long-term benefit is observed among intermediate-risk AS patients is unknown. The purpose of this study was to assess health status outcomes through 5 years in intermediate risk patients treated with a self-expanding TAVR prosthesis or SAVR using data from the SURTAVI (Surgical Replacement and Transcatheter Aortic Valve Implantation) trial. Intermediate-risk patients randomized to transfemoral TAVR or SAVR in the SURTAVI trial had disease-specific health status assessed at baseline, 30 days, and annually to 5 years using the Kansas City Cardiomyopathy Questionnaire (KCCQ). Health status was compared between groups using fixed effects repeated measures modelling. Of the 1,584 patients (TAVR, n = 805; SAVR, n = 779) included in the analysis, health status improved more rapidly after TAVR compared with SAVR. However, by 1 year, both groups experienced large health status benefits (mean change in KCCQ-Overall Summary Score (KCCQ-OS) from baseline: TAVR: 20.5 ± 22.4; SAVR: 20.5 ± 22.2). This benefit was sustained, albeit modestly attenuated, at 5 years (mean change in KCCQ-OS from baseline: TAVR: 15.4 ± 25.1; SAVR: 14.3 ± 24.2). There were no significant differences in health status between the cohorts at 1 year or beyond. Similar findings were observed in the KCCQ subscales, although a substantial attenuation of benefit was noted in the physical limitation subscale over time in both groups. In intermediate-risk AS patients, both transfemoral TAVR and SAVR resulted in comparable and durable health status benefits to 5 years. Further research is necessary to elucidate the mechanisms for the small decline in health status noted at 5 years compared with 1 year in both groups. (Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement [SURTAVI]; NCT01586910) [Display omitted] [ABSTRACT FROM AUTHOR]
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- 2024
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43. Large ascending aortic pseudoaneurysm with focal dissection after coronary artery bypass surgery
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Anderson, Devon, additional, Xue, Anna, additional, Wong, Samantha, additional, Kiaii, Bob, additional, and Catrip-Torres, Jorge Manuel, additional
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- 2023
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44. Cardiac-Referenced Leukocyte Telomere Length and Outcomes After Cardiovascular Surgery
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Yin, Hao, Akawi, Oula, Fox, Stephanie A., Li, Fuyan, O'Neil, Caroline, Balint, Brittany, Arpino, John-Michael, Watson, Alanna, Wong, Jorge, Guo, Linrui, Quantz, MacKenzie A., Nagpal, A. Dave, Kiaii, Bob, Chu, Michael W.A., and Pickering, J. Geoffrey
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- 2018
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45. Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial
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SALA, JORGELINA, CARTASEGNA, LUIS, VICO, MARISA, HOMINAL, MIGUEL ANGEL, HASBANI, EDUARDO, CACCAVO, ALBERTO, ZAIDMAN, CESAR, VOGEL, DANIEL, HRABAR, ADRIAN, SCHYGIEL, PABLO OMAR, CUNEO, CARLOS, LUQUEZ, HUGO, MACKINNON, IGNACIO J., AHUAD GUERRERO, RODOLFO ANDRES, COSTABEL, JUAN PABLO, BARTOLACCI, INES PALMIRA, MONTANA, OSCAR, BARBIERI, MARIA, GOMEZ VILAMAJO, OSCAR, GARCIA DURAN, RUBEN OMAR, SCHIAVI, LILIA BEATRIZ, GARRIDO, MARCELO, INGARAMO, ADRIAN, BORDONAVA, ANSELMO PAULINO, PELAGAGGE, MARIA JOSE, NOVARETTO, LEONARDO, ALBISU DI GENNERO, JUAN PABLO, IBANEZ SAGGIA, LUZ MARIA, ALVAREZ, MOIRA, VITA, NESTOR ALEJANDRO, MACIN, STELLA MARIS, DRAN, RICARDO DARIO, CARDONA, MARCELO, GUZMAN, LUIS, SARJANOVICH, RODOLFO JUAN, CUADRADO, JESUS, NANI, SEBASTIAN, LITVAK BRUNO, MARCOS RAUL, CHACON, CAROLINA, MAFFEI, LAURA ELENA, GRINFELD, DIEGO, VENSENTINI, NATALIA, MAJUL, CLAUDIO RODOLFO, LUCIARDI, HECTOR LUCAS, GONZALEZ COLASO, PATRICIA DEL CARMEN, FERRE PACORA, FREDY ANTONI, VAN DEN HEUVEL, PAUL, VERHAMME, PETER, ECTOR, BAVO, DEBONNAIRE, PHILIPPE, VAN DE BORNE, PHILIPPE, LEROY, JEAN, SCHROE, HERMAN, VRANCKX, PASCAL, ELEGEERT, IVAN, HOFFER, ETIENNE, DUJARDIN, KARL, INDIO DO BRASIL, CLARISSE, PRECOMA, DALTON, ABRANTES, JOSE ANTONIO, MANENTI, EULER, REIS, GILMAR, SARAIVA, JOSE, MAIA, LILIA, HERNANDES, MAURO, ROSSI, PAULO, ROSSI DOS SANTOS, FABIO, ZIMMERMANN, SERGIO LUIZ, RECH, RAFAEL, ABIB JR, EDUARDO, LEAES, PAULO, BOTELHO, ROBERTO, DUTRA, OSCAR, SOUZA, WEIMAR, BRAILE, MARIA, IZUKAWA, NILO, NICOLAU, JOSE CARLOS, TANAJURA, LUIZ FERNANDO, SERRANO JUNIOR, CARLOS VICENTE, MINELLI, CESAR, NASI, LUIZ ANTONIO, OLIVEIRA, LIVIA, DE CARVALHO CANTARELLI, MARCELO JOSE, TYTUS, RICHARD, PANDEY, SHEKHAR, LONN, EVA, CHA, JAMES, VIZEL, SAUL, BABAPULLE, MOHAN, LAMY, ANDRE, SAUNDERS, KEVIN, BERLINGIERI, JOSEPH, KIAII, BOB, BHARGAVA, RAKESH, MEHTA, PRAVINSAGAR, HILL, LAURIE, FELL, DAVID, LAM, ANDY, AL-QOOFI, FAISAL, BROWN, CRAIG, PETRELLA, ROBERT, RICCI, JOSEPH A, GLANZ, ANTHONY, NOISEUX, NICOLAS, BAINEY, KEVIN, MERALI, FATIMA, HEFFERNAN, MICHAEL, DELLA SIEGA, ANTHONY, DAGENAIS, GILLES R, DAGENAIS, FRANCOIS, BRULOTTE, STEEVE, NGUYEN, MICHEL, HARTLEIB, MICHAEL, GUZMAN, RANDOLPH, BOURGEOIS, RONALD, RUPKA, DENNIS, KHAYKIN, YAARIV, GOSSELIN, GILBERT, HUYNH, THAO, PILON, CLAUDE, CAMPEAU, JEAN, PICHETTE, FRANCIS, DIAZ, ARIEL, JOHNSTON, JAMES, SHUKLE, PRAVIN, HIRSCH, GREGORY, RHEAULT, PAUL, CZARNECKI, WLODZIMIERZ, ROY, ANNIE, NAWAZ, SHAH, FREMES, STEPHEN, SHUKLA, DINKAR, JANO, GABRIEL, COBOS, JORGE LEONARDO, CORBALAN, RAMON, MEDINA, MARCELO, NAHUELPAN, LEONARDO, RAFFO, CARLOS, PEREZ, LUIS, POTTHOFF, SERGIO, STOCKINS, BENJAMIN, SEPULVEDA, PABLO, PINCETTI, CHRISTIAN, VEJAR, MARGARITA, TIAN, HONGYAN, WU, XUESI, KE, YUANNAN, JIA, KAIYING, YIN, PENGFEI, WANG, ZHAOHUI, YU, LITIAN, WU, SHULIN, WU, ZONGQUI, LIU, SHAO WEN, BAI, XIAO JUAN, ZHENG, YANG, YANG, PING, YANG, YUN MEI, ZHANG, JIWEI, GE, JUNBO, CHEN, XIAO PING, LI, JUNXIA, HU, TAO HONG, ZHANG, RUIYAN, ZHENG, ZHE, CHEN, XIN, TAO, LIANG, LI, JIANPING, HUANG, WEIJIAN, FU, GUOSHENG, LI, CHUNJIAN, DONG, YUGANG, WANG, CHUNSHENG, ZHOU, XINMIN, KONG, YE, SOTOMAYOR, ARISTIDES, ACCINI MENDOZA, JOSE LUIS, CASTILLO, HENRY, URINA, MIGUEL, AROCA, GUSTAVO, PEREZ, MARITZA, MOLINA DE SALAZAR, DORA INES, SANCHEZ VALLEJO, GREGORIO, FERNANDO, MANZUR J, GARCIA, HENRY, GARCIA, LUIS HERNANDO, ARCOS, EDGAR, GOMEZ, JUAN, CUERVO MILLAN, FRANCISCO, TRUJILLO DADA, FREDY ALBERTO, VESGA, BORIS, MORENO SILGADO, GUSTAVO ADOLFO, ZIDKOVA, EVA, LUBANDA, JEAN-CLAUDE, KALETOVA, MARKETA, KRYZA, RADIM, MARCINEK, GABRIEL, RICHTER, MAREK, SPINAR, JINDRICH, MATUSKA, JIRI, TESAK, MARTIN, MOTOVSKA, ZUZANA, BRANNY, MARIAN, MALY, JIRI, MALY, MARTIN, WIENDL, MARTIN, FOLTYNOVA CAISOVA, LENKA, SLABY, JOSEF, VOJTISEK, PETR, PIRK, JAN, SPINAROVA, LENKA, BENESOVA, MIROSLAVA, CANADYOVA, JULIA, HOMZA, MIROSLAV, FLORIAN, JINDRICH, POLASEK, ROSTISLAV, COUFAL, ZDENEK, SKALNIKOVA, VLADIMIRA, BRAT, RADIM, BRTKO, MIROSLAV, JANSKY, PETR, LINDNER, JAROSLAV, MARCIAN, PAVEL, STRAKA, ZBYNEK, TRETINA, MARTIN, DUARTE, YAN CARLOS, POW CHON LONG, FREDDY, SANCHEZ, MAYRA, LOPEZ, JOSE, PERUGACHI, CARMITA, MARMOL, RICARDO, TRUJILLO, FREDDY, TERAN, PABLO, TUOMILEHTO, JAAKKO, TUOMILEHTO, HENRI, TUOMINEN, MARJA-LEENA, KANTOLA, ILKKA, STEG, GABRIEL, ABOYANS, VICTOR, LECLERCQ, FLORENCE, FERRARI, EMILE, BOCCARA, FRANCK, MESSAS, EMMANUEL, MISMETTI, PATRICK, SEVESTRE, MARIE ANTOINETTE, CAYLA, GUILLAUME, MOTREFF, PASCAL, STOERK, STEFAN, DUENGEN, HANS-DIRK, STELLBRINK, CHRISTOPH, GUEROCAK, OSMAN, KADEL, CHRISTOPH, BRAUN-DULLAEUS, RUEDIGER, JESERICH, MICHAEL, OPITZ, CHRISTIAN, VOEHRINGER, HANS-FRIEDRICH, APPEL, KARL-FRIEDRICH, WINKELMANN, BERNHARD, DORSEL, THOMAS, NIKOL, SIGRID, DARIUS, HARALD, RANFT, JURGEN, SCHELLONG, SEBASTIAN, JUNGMAIR, WOLFGANG, DAVIERWALA, PIROZE, VORPAHL, MARC, BAJNOK, LASZLO, LASZLO, ZOLTAN, NOORI, EBRAHIM, VERESS, GABOR, VERTES, ANDRAS, ZSARY, ANDRAS, KIS, ERNO, KORANYI, LASZLO, BAKAI, JUDIT, BODA, ZOLTAN, POOR, FERENC, JARAI, ZOLTAN, KEMENY, VENDEL, BARTON, JOHN, MCADAM, BRENDAN, MURPHY, ANDREW, CREAN, PETER, MAHON, NIALL, CURTIN, RONAN, MACNEILL, BRIAIN, DINNEEN, SEAN, HALABI, MAJDI, ZIMLICHMAN, REUVEN, ZELTSER, DAVID, TURGEMAN, YOAV, KLAINMAN, ELIEZER, LEWIS, BASIL, KATZ, AMOS, ATAR, SHAUL, NIKOLSKY, EUGENIA, BOSI, STEFANO, NALDI, MONICA, FAGGIANO, POMPILIO, ROBBA, DEBORA, MOS, LUCIO, SINAGRA, GIANFRANCO, COSMI, FRANCO, OLTRONA VISCONTI, LUIGI, CARMINE, DE MATTEIS, DI PASQUALE, GIUSEPPE, DI BIASE, MATTEO, MANDORLA, SARA, BERNARDINANGELI, MARINO, PICCINNI, GIOVANNI CARLO, GULIZIA, MICHELE MASSIMO, GALVANI, MARCELLO, VENTURI, FLAVIO, MOROCUTTI, GIORGIO, BALDIN, MARIA GRAZIA, OLIVIERI, CARLO, PERNA, GIAN PIERO, CIRRINCIONE, VINCENZO, KANNO, TAKAYASU, DAIDA, HIROYUKI, OZAKI, YUKIO, MIYAMOTO, NAOMASA, HIGASHIUE, SHINICHI, DOMAE, HIROSHI, HOSOKAWA, SHINOBU, KOBAYASHI, HIROO, KURAMOCHI, TAKEHIKO, FUJII, KENSHI, MIZUTOMI, KAZUAKI, SAKU, KEIJIRO, KIMURA, KAZUO, HIGUCHI, YOSHIHARU, ABE, MITSUNORI, OKUDA, HARUHITO, NODA, TOSHIYUKI, MITA, TERUAKI, HIRAYAMA, ATSUSHI, ONAKA, HARUHIKO, INOKO, MORIAKI, HIROKAMI, MITSUGU, OKUBO, MUNENORI, AKATSUKA, YUTAKA, IMAMAKI, MIZUHO, KAMIYA, HARUO, MANITA, MAMORU, HIMI, TOSHIHARU, UENO, HIDEKI, HISAMATSU, YUJI, AKO, JUNYA, NISHINO, YASUHIRO, KAWAKAMI, HIDEO, YAMADA, YUTAKA, KORETSUNE, YUKIHIRO, YAMADA, TAKAHISA, YOSHIDA, TETSURO, SHIMOMURA, HIDEKI, KINOSHITA, NORIYUKI, TAKAHASHI, AKIHIKO, YUSOFF, KHALID, WAN AHMAD, WAN AZMAN, ABU HASSAN, MUHAMMAD RADZI, KASIM, SAZZLI, ABDUL RAHIM, AIZAI AZAN, MOHD ZAMRIN, DIMON, MACHIDA, MASAHARU, HIGASHINO, YORIHIKO, UTSU, NORIAKI, NAKANO, AKIHIKO, NAKAMURA, SHIGERU, HASHIMOTO, TETSUO, ANDO, KENJI, SAKAMOTO, TOMOHIRO, PRINS, F.J., LOK, DIRK, MILHOUS, JOHANNES GERT-JAN, VIERGEVER, ERIC, WILLEMS, FRANK, SWART, HENK, ALINGS, MARCO, BREEDVELD, ROB, DE VRIES, KEES-JAN, VAN DER BORGH, ROGER, OEI, FANNY, ZOET-NUGTEREN, STIENEKE, KRAGTEN, HANS, HERRMAN, JEAN PAUL, VAN BERGEN, PAUL, GOSSELINK, MARCEL, HOEKSTRA, EDUARD, ZEGERS, ERWIN, RONNER, EELKO, DEN HARTOG, FRANK, BARTELS, GERARD, NIEROP, PETER, VAN DER ZWAAN, COEN, VAN ECK, JACOB, VAN GORSELEN, EDWIN, GROENEMEIJER, BJORN, HOOGSLAG, PIETER, DE GROOT, MARC ROBERT, LOYOLA, ALDRIN, SULIT, DENNIS JOSE, REY, NANNETTE, ABOLA, MARIA TERESA, MORALES, DANTE, PALOMARES, ELLEN, ABAT, MARC EVANS, ROGELIO, GREGORIO, CHUA, PHILIP, DEL PILAR, JOSE CARLO, ALCARAZ, JOHN DENNIS, EBO, GERALDINE, TIRADOR, LOUIE, CRUZ, JOSEFINA, ANONUEVO, JOHN, PITARGUE, ARTHUR, JANION, MARIANNA, GUZIK, TOMASZ, GAJOS, GRZEGORZ, ZABOWKA, MACIEJ, RYNKIEWICZ, ANDRZEJ, BRONCEL, MARLENA, SZUBA, ANDRZEJ, CZARNECKA, DANUTA, MAGA, PAWEL, STRAZHESKO, IRINA, VASYUK, YURY, SIZOVA, ZHANNA, POZDNYAKOV, YURY, BARBARASH, OLGA, VOEVODA, MIKHAIL, POPONINA, TATIANA, REPIN, ALEXEY, OSIPOVA, IRINA, EFREMUSHKINA, ANNA, NOVIKOVA, NINA, AVERKOV, OLEG, ZATEYSHCHIKOV, DMITRY, VERTKIN, ARKADIY, AUSHEVA, AZA, COMMERFORD, PATRICK, SEEDAT, SAADIYA, VAN ZYL, LOUIS, ENGELBRECHT, JAN, MAKOTOKO, ELLEN MAKONLI, PRETORIUS, CATHARINA ELIZABETH, MOHAMED, ZAID, HORAK, ADRIAN, MABIN, THOMAS, KLUG, ERIC, BAE, JANG-HO, KIM, CHEOLHO, KIM, CHONG-JIN, KIM, DONG-SOO, KIM, YONG JIN, JOO, SEUNGJAE, HA, JONG-WON, PARK, CHUL SOO, KIM, JANG YOUNG, KIM, YOUNG-KWON, JARNERT, CHRISTINA, MOOE, THOMAS, DELLBORG, MIKAEL, TORSTENSSON, INGEMAR, ALBERTSSON, PER, JOHANSSON, LARS, AL-KHALILI, FARIS, ALMROTH, HENRIK, ANDERSSON, TOMMY, PANTEV, EMIL, TENGMARK, BENGT-OLOV, LIU, BO, RASMANIS, GUNDARS, WAHLGREN, CARL-MAGNUS, MOCCETTI, TIZIANO, PARKHOMENKO, ALEXANDER, TSELUYKO, VIRA, VOLKOV, VOLODYMYR, KOVAL, OLENA, KONONENKO, LYUDMYLA, PROKHOROV, OLEKSANDR, VDOVYCHENKO, VALERIY, BAZYLEVYCH, ANDRIY, RUDENKO, LEONID, VIZIR, VADYM, KARPENKO, OLEKSANDR, MALYNOVSKY, YAROSLAV, KOVAL, VALENTYNA, STOROZHUK, BORYS, COTTON, JAMES, VENKATARAMAN, ASOK, MORIARTY, ANDREW, CONNOLLY, DEREK, DAVEY, PATRICK, SENIOR, ROXY, BIRDI, INDERPAUL, CALVERT, JOHN, DONNELLY, PATRICK, TREVELYAN, JASPER, CARTER, JUSTIN, PEACE, AARON, AUSTIN, DAVID, KUKREJA, NEVILLE, HILTON, THOMAS, SRIVASTAVA, SUNNY, WALSH, RONALD, FIELDS, RONALD, HAKAS, JOSEPH, PORTNAY, EDWARD, GOGIA, HARINDER, SALACATA, ABRAHAM, HUNTER, JOHN J., BACHARACH, J MICHAEL, SHAMMAS, NICOLAS, SURESH, DAMODHAR, SCHNEIDER, RICKY, GURBEL, PAUL, BANERJEE, SUBHASH, GRENA, PAUL, BEDWELL, NOEL, SLOAN, STEPHEN, LUPOVITCH, STEVEN, SONI, ANAND, GIBSON, KATHLEEN, SANGRIGOLI, RENEE, MEHTA, RAJENDRA, I-HSUAN TSAI, PETER, GILLESPIE, EVE, DEMPSEY, STEPHEN, HAMROFF, GLENN, BLACK, ROBERT, LADER, ELLIS, KOSTIS, JOHN B., BITTNER, VERA, MCGUINN, WILLIAM, BRANCH, KELLEY, MALHOTRA, VINAY, MICHAELSON, STEPHEN, VACANTE, MICHAEL, MCCORMICK, MATTHEW, ARIMIE, RALUCA, CAMP, ALAN, DAGHER, GEORGE, KOSHY, N. MATHEW, THEW, STEPHEN, COSTELLO, FREDERICK, HEIMAN, MARK, CHILTON, ROBERT, MORAN, MICHAEL, ADLER, FREDRIC, COMEROTA, ANTHONY, SEIWERT, ANDREW, FRENCH, WILLIAM, SEROTA, HARVEY, HARRISON, ROBERT, BAKAEEN, FAISAL, OMER, SHUAB, CHANDRA, LOKESH, WHELAN, ALAN, BOYLE, ANDREW, ROBERTS-THOMSON, PHILIP, ROGERS, JAMES, CARROLL, PATRICK, COLQUHOUN, DAVID, SHAW, JAMES, BLOMBERY, PETER, AMERENA, JOHN, HII, CHRIS, ROYSE, ALISTAIR, SINGH, BHUWAN, SELVANAYAGAM, JOSEPH, JANSEN, SHIRLEY, LO, WINGCHI, HAMMETT, CHRISTOPHER, POULTER, ROHAN, NARASIMHAN, SESHASAYEE, WIGGERS, HENRIK, NIELSEN, HENRIK, GISLASON, GUNNAR, KOBER, LARS, HOULIND, KIM, BOENELYKKE SOERENSEN, VIBEKE, DIXEN, ULRIK, REFSGAARD, JENS, ZEUTHEN, ELISABETH, SOEGAARD, PETER, HRANAI, MARIAN, GASPAR, LUDOVIT, PELLA, DANIEL, HATALOVA, KATARINA, DROZDAKOVA, ERIKA, COMAN, IOAN, DIMULESCU, DOINA, VINEREANU, DRAGOS, CINTEZA, MIRCEA, SINESCU, CRINA, ARSENESCU, CATALINA, BENEDEK, IMRE, BOBESCU, ELENA, DOBREANU, DAN, GAITA, DAN, IANCU, ADRIAN, ILIESIU, ADRIANA, LIGHEZAN, DANIEL, PETRESCU, LUCIAN, PIRVU, OCTAVIAN, TEODORESCU, IULIA, TESLOIANU, DAN, VINTILA, MARIUS MARCIAN, CHIONCEL, OVIDIU, Connolly, Stuart J, Eikelboom, John W, Bosch, Jackie, Dagenais, Gilles, Dyal, Leanne, Lanas, Fernando, Metsarinne, Kaj, O'Donnell, Martin, Dans, Anthony L, Ha, Jong-Won, Parkhomenko, Alexandr N, Avezum, Alvaro A, Lonn, Eva, Lisheng, Liu, Torp-Pedersen, Christian, Widimsky, Petr, Maggioni, Aldo P, Felix, Camilo, Keltai, Katalin, Hori, Masatsugu, Yusoff, Khalid, Guzik, Tomasz J, Bhatt, Deepak L, Branch, Kelley R H, Cook Bruns, Nancy, Berkowitz, Scott D, Anand, Sonia S, Varigos, John D, Fox, Keith A A, and Yusuf, Salim
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46. Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial
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SALA, JORGELINA, CARTASEGNA, LUIS, VICO, MARISA, HOMINAL, MIGUEL ANGEL, HASBANI, EDUARDO, CACCAVO, ALBERTO, ZAIDMAN, CESAR, VOGEL, DANIEL, HRABAR, ADRIAN, SCHYGIEL, PABLO OMAR, CUNEO, CARLOS, LUQUEZ, HUGO, MACKINNON, IGNACIO J., AHUAD GUERRERO, RODOLFO ANDRES, COSTABEL, JUAN PABLO, BARTOLACCI, INES PALMIRA, MONTANA, OSCAR, BARBIERI, MARIA, GOMEZ VILAMAJO, OSCAR, GARCIA DURAN, RUBEN OMAR, SCHIAVI, LILIA BEATRIZ, GARRIDO, MARCELO, INGARAMO, ADRIAN, BORDONAVA, ANSELMO PAULINO, PELAGAGGE, MARIA JOSE, NOVARETTO, LEONARDO, ALBISU DI GENNERO, JUAN PABLO, IBANEZ SAGGIA, LUZ MARIA, ALVAREZ, MOIRA, VITA, NESTOR ALEJANDRO, MACIN, STELLA MARIS, DRAN, RICARDO DARIO, CARDONA, MARCELO, GUZMAN, LUIS, SARJANOVICH, RODOLFO JUAN, CUADRADO, JESUS, NANI, SEBASTIAN, LITVAK BRUNO, MARCOS RAUL, CHACON, CAROLINA, MAFFEI, LAURA ELENA, GRINFELD, DIEGO, VENSENTINI, NATALIA, MAJUL, CLAUDIO RODOLFO, LUCIARDI, HECTOR LUCAS, GONZALEZ COLASO, PATRICIA DEL CARMEN, FERRE PACORA, FREDY ANTONI, VAN DEN HEUVEL, PAUL, VERHAMME, PETER, ECTOR, BAVO, DEBONNAIRE, PHILIPPE, VAN DE BORNE, PHILIPPE, LEROY, JEAN, SCHROE, HERMAN, VRANCKX, PASCAL, ELEGEERT, IVAN, HOFFER, ETIENNE, DUJARDIN, KARL, INDIO DO BRASIL, CLARISSE, PRECOMA, DALTON, ABRANTES, JOSE ANTONIO, MANENTI, EULER, REIS, GILMAR, SARAIVA, JOSE, MAIA, LILIA, HERNANDES, MAURO, ROSSI, PAULO, ROSSI DOS SANTOS, FABIO, ZIMMERMANN, SERGIO LUIZ, RECH, RAFAEL, ABIB JR, EDUARDO, LEAES, PAULO, BOTELHO, ROBERTO, DUTRA, OSCAR, SOUZA, WEIMAR, BRAILE, MARIA, IZUKAWA, NILO, NICOLAU, JOSE CARLOS, TANAJURA, LUIZ FERNANDO, SERRANO JUNIOR, CARLOS VICENTE, MINELLI, CESAR, NASI, LUIZ ANTONIO, OLIVEIRA, LIVIA, DE CARVALHO CANTARELLI, MARCELO JOSE, TYTUS, RICHARD, PANDEY, SHEKHAR, LONN, EVA, CHA, JAMES, VIZEL, SAUL, BABAPULLE, MOHAN, LAMY, ANDRE, SAUNDERS, KEVIN, BERLINGIERI, JOSEPH, KIAII, BOB, BHARGAVA, RAKESH, MEHTA, PRAVINSAGAR, HILL, LAURIE, FELL, DAVID, LAM, ANDY, AL-QOOFI, FAISAL, BROWN, CRAIG, PETRELLA, ROBERT, RICCI, JOSEPH A, GLANZ, ANTHONY, NOISEUX, NICOLAS, BAINEY, KEVIN, MERALI, FATIMA, HEFFERNAN, MICHAEL, DELLA SIEGA, ANTHONY, DAGENAIS, GILLES R, DAGENAIS, FRANCOIS, BRULOTTE, STEEVE, NGUYEN, MICHEL, HARTLEIB, MICHAEL, GUZMAN, RANDOLPH, BOURGEOIS, RONALD, RUPKA, DENNIS, KHAYKIN, YAARIV, GOSSELIN, GILBERT, HUYNH, THAO, PILON, CLAUDE, CAMPEAU, JEAN, PICHETTE, FRANCIS, DIAZ, ARIEL, JOHNSTON, JAMES, SHUKLE, PRAVIN, HIRSCH, GREGORY, RHEAULT, PAUL, CZARNECKI, WLODZIMIERZ, ROY, ANNIE, NAWAZ, SHAH, FREMES, STEPHEN, SHUKLA, DINKAR, JANO, GABRIEL, COBOS, JORGE LEONARDO, CORBALAN, RAMON, MEDINA, MARCELO, NAHUELPAN, LEONARDO, RAFFO, CARLOS, PEREZ, LUIS, POTTHOFF, SERGIO, STOCKINS, BENJAMIN, SEPULVEDA, PABLO, PINCETTI, CHRISTIAN, VEJAR, MARGARITA, TIAN, HONGYAN, WU, XUESI, KE, YUANNAN, JIA, KAIYING, YIN, PENGFEI, WANG, ZHAOHUI, YU, LITIAN, WU, SHULIN, WU, ZONGQUI, LIU, SHAO WEN, BAI, XIAO JUAN, ZHENG, YANG, YANG, PING, YANG, YUN MEI, ZHANG, JIWEI, GE, JUNBO, CHEN, XIAO PING, LI, JUNXIA, HU, TAO HONG, ZHANG, RUIYAN, ZHENG, ZHE, CHEN, XIN, TAO, LIANG, LI, JIANPING, HUANG, WEIJIAN, FU, GUOSHENG, LI, CHUNJIAN, DONG, YUGANG, WANG, CHUNSHENG, ZHOU, XINMIN, KONG, YE, SOTOMAYOR, ARISTIDES, ACCINI MENDOZA, JOSE LUIS, CASTILLO, HENRY, URINA, MIGUEL, AROCA, GUSTAVO, PEREZ, MARITZA, MOLINA DE SALAZAR, DORA INES, SANCHEZ VALLEJO, GREGORIO, FERNANDO, MANZUR J, GARCIA, HENRY, GARCIA, LUIS HERNANDO, ARCOS, EDGAR, GOMEZ, JUAN, CUERVO MILLAN, FRANCISCO, TRUJILLO DADA, FREDY ALBERTO, VESGA, BORIS, MORENO SILGADO, GUSTAVO ADOLFO, ZIDKOVA, EVA, LUBANDA, JEAN-CLAUDE, KALETOVA, MARKETA, KRYZA, RADIM, MARCINEK, GABRIEL, RICHTER, MAREK, SPINAR, JINDRICH, MATUSKA, JIRI, TESAK, MARTIN, MOTOVSKA, ZUZANA, BRANNY, MARIAN, MALY, JIRI, MALY, MARTIN, WIENDL, MARTIN, FOLTYNOVA CAISOVA, LENKA, SLABY, JOSEF, VOJTISEK, PETR, PIRK, JAN, SPINAROVA, LENKA, BENESOVA, MIROSLAVA, CANADYOVA, JULIA, HOMZA, MIROSLAV, FLORIAN, JINDRICH, POLASEK, ROSTISLAV, COUFAL, ZDENEK, SKALNIKOVA, VLADIMIRA, BRAT, RADIM, BRTKO, MIROSLAV, JANSKY, PETR, LINDNER, JAROSLAV, MARCIAN, PAVEL, STRAKA, ZBYNEK, TRETINA, MARTIN, DUARTE, YAN CARLOS, POW CHON LONG, FREDDY, SANCHEZ, MAYRA, LOPEZ, JOSE, PERUGACHI, CARMITA, MARMOL, RICARDO, TRUJILLO, FREDDY, TERAN, PABLO, TUOMILEHTO, JAAKKO, TUOMILEHTO, HENRI, TUOMINEN, MARJA-LEENA, KANTOLA, ILKKA, STEG, GABRIEL, ABOYANS, VICTOR, LECLERCQ, FLORENCE, FERRARI, EMILE, BOCCARA, FRANCK, MESSAS, EMMANUEL, MISMETTI, PATRICK, SEVESTRE, MARIE ANTOINETTE, CAYLA, GUILLAUME, MOTREFF, PASCAL, STOERK, STEFAN, DUENGEN, HANS-DIRK, STELLBRINK, CHRISTOPH, GUEROCAK, OSMAN, KADEL, CHRISTOPH, BRAUN-DULLAEUS, RUEDIGER, JESERICH, MICHAEL, OPITZ, CHRISTIAN, VOEHRINGER, HANS-FRIEDRICH, APPEL, KARL-FRIEDRICH, WINKELMANN, BERNHARD, DORSEL, THOMAS, NIKOL, SIGRID, DARIUS, HARALD, RANFT, JURGEN, SCHELLONG, SEBASTIAN, JUNGMAIR, WOLFGANG, DAVIERWALA, PIROZE, VORPAHL, MARC, BAJNOK, LASZLO, LASZLO, ZOLTAN, NOORI, EBRAHIM, VERESS, GABOR, VERTES, ANDRAS, ZSARY, ANDRAS, KIS, ERNO, KORANYI, LASZLO, BAKAI, JUDIT, BODA, ZOLTAN, POOR, FERENC, JARAI, ZOLTAN, KEMENY, VENDEL, BARTON, JOHN, MCADAM, BRENDAN, MURPHY, ANDREW, CREAN, PETER, MAHON, NIALL, CURTIN, RONAN, MACNEILL, BRIAIN, DINNEEN, SEAN, HALABI, MAJDI, ZIMLICHMAN, REUVEN, ZELTSER, DAVID, TURGEMAN, YOAV, KLAINMAN, ELIEZER, LEWIS, BASIL, KATZ, AMOS, ATAR, SHAUL, NIKOLSKY, EUGENIA, BOSI, STEFANO, NALDI, MONICA, FAGGIANO, POMPILIO, ROBBA, DEBORA, MOS, LUCIO, SINAGRA, GIANFRANCO, COSMI, FRANCO, OLTRONA VISCONTI, LUIGI, CARMINE, DE MATTEIS, DI PASQUALE, GIUSEPPE, DI BIASE, MATTEO, MANDORLA, SARA, BERNARDINANGELI, MARINO, PICCINNI, GIOVANNI CARLO, GULIZIA, MICHELE MASSIMO, GALVANI, MARCELLO, VENTURI, FLAVIO, MOROCUTTI, GIORGIO, BALDIN, MARIA GRAZIA, OLIVIERI, CARLO, PERNA, GIAN PIERO, CIRRINCIONE, VINCENZO, KANNO, TAKAYASU, DAIDA, HIROYUKI, OZAKI, YUKIO, MIYAMOTO, NAOMASA, HIGASHIUE, SHINICHI, DOMAE, HIROSHI, HOSOKAWA, SHINOBU, KOBAYASHI, HIROO, KURAMOCHI, TAKEHIKO, FUJII, KENSHI, MIZUTOMI, KAZUAKI, SAKU, KEIJIRO, KIMURA, KAZUO, HIGUCHI, YOSHIHARU, ABE, MITSUNORI, OKUDA, HARUHITO, NODA, TOSHIYUKI, MITA, TERUAKI, HIRAYAMA, ATSUSHI, ONAKA, HARUHIKO, INOKO, MORIAKI, HIROKAMI, MITSUGU, OKUBO, MUNENORI, AKATSUKA, YUTAKA, IMAMAKI, MIZUHO, KAMIYA, HARUO, MANITA, MAMORU, HIMI, TOSHIHARU, UENO, HIDEKI, HISAMATSU, YUJI, AKO, JUNYA, NISHINO, YASUHIRO, KAWAKAMI, HIDEO, YAMADA, YUTAKA, KORETSUNE, YUKIHIRO, YAMADA, TAKAHISA, YOSHIDA, TETSURO, SHIMOMURA, HIDEKI, KINOSHITA, NORIYUKI, TAKAHASHI, AKIHIKO, YUSOFF, KHALID, WAN AHMAD, WAN AZMAN, ABU HASSAN, MUHAMMAD RADZI, KASIM, SAZZLI, ABDUL RAHIM, AIZAI AZAN, MOHD ZAMRIN, DIMON, MACHIDA, MASAHARU, HIGASHINO, YORIHIKO, UTSU, NORIAKI, NAKANO, AKIHIKO, NAKAMURA, SHIGERU, HASHIMOTO, TETSUO, ANDO, KENJI, SAKAMOTO, TOMOHIRO, PRINS, F.J., LOK, DIRK, MILHOUS, JOHANNES GERT-JAN, VIERGEVER, ERIC, WILLEMS, FRANK, SWART, HENK, ALINGS, MARCO, BREEDVELD, ROB, DE VRIES, KEES-JAN, VAN DER BORGH, ROGER, OEI, FANNY, ZOET-NUGTEREN, STIENEKE, KRAGTEN, HANS, HERRMAN, JEAN PAUL, VAN BERGEN, PAUL, GOSSELINK, MARCEL, HOEKSTRA, EDUARD, ZEGERS, ERWIN, RONNER, EELKO, DEN HARTOG, FRANK, BARTELS, GERARD, NIEROP, PETER, VAN DER ZWAAN, COEN, VAN ECK, JACOB, VAN GORSELEN, EDWIN, GROENEMEIJER, BJORN, HOOGSLAG, PIETER, DE GROOT, MARC ROBERT, LOYOLA, ALDRIN, SULIT, DENNIS JOSE, REY, NANNETTE, ABOLA, MARIA TERESA, MORALES, DANTE, PALOMARES, ELLEN, ABAT, MARC EVANS, ROGELIO, GREGORIO, CHUA, PHILIP, DEL PILAR, JOSE CARLO, ALCARAZ, JOHN DENNIS, EBO, GERALDINE, TIRADOR, LOUIE, CRUZ, JOSEFINA, ANONUEVO, JOHN, PITARGUE, ARTHUR, JANION, MARIANNA, GUZIK, TOMASZ, GAJOS, GRZEGORZ, ZABOWKA, MACIEJ, RYNKIEWICZ, ANDRZEJ, BRONCEL, MARLENA, SZUBA, ANDRZEJ, CZARNECKA, DANUTA, MAGA, PAWEL, STRAZHESKO, IRINA, VASYUK, YURY, SIZOVA, ZHANNA, POZDNYAKOV, YURY, BARBARASH, OLGA, VOEVODA, MIKHAIL, POPONINA, TATIANA, REPIN, ALEXEY, OSIPOVA, IRINA, EFREMUSHKINA, ANNA, NOVIKOVA, NINA, AVERKOV, OLEG, ZATEYSHCHIKOV, DMITRY, VERTKIN, ARKADIY, AUSHEVA, AZA, COMMERFORD, PATRICK, SEEDAT, SAADIYA, VAN ZYL, LOUIS, ENGELBRECHT, JAN, MAKOTOKO, ELLEN MAKONLI, PRETORIUS, CATHARINA ELIZABETH, MOHAMED, ZAID, HORAK, ADRIAN, MABIN, THOMAS, KLUG, ERIC, BAE, JANG-HO, KIM, CHEOLHO, KIM, CHONG-JIN, KIM, DONG-SOO, KIM, YONG JIN, JOO, SEUNGJAE, HA, JONG-WON, PARK, CHUL SOO, KIM, JANG YOUNG, KIM, YOUNG-KWON, JARNERT, CHRISTINA, MOOE, THOMAS, DELLBORG, MIKAEL, TORSTENSSON, INGEMAR, ALBERTSSON, PER, JOHANSSON, LARS, AL-KHALILI, FARIS, ALMROTH, HENRIK, ANDERSSON, TOMMY, PANTEV, EMIL, TENGMARK, BENGT-OLOV, LIU, BO, RASMANIS, GUNDARS, WAHLGREN, CARL-MAGNUS, MOCCETTI, TIZIANO, PARKHOMENKO, ALEXANDER, TSELUYKO, VIRA, VOLKOV, VOLODYMYR, KOVAL, OLENA, KONONENKO, LYUDMYLA, PROKHOROV, OLEKSANDR, VDOVYCHENKO, VALERIY, BAZYLEVYCH, ANDRIY, RUDENKO, LEONID, VIZIR, VADYM, KARPENKO, OLEKSANDR, MALYNOVSKY, YAROSLAV, KOVAL, VALENTYNA, STOROZHUK, BORYS, COTTON, JAMES, VENKATARAMAN, ASOK, MORIARTY, ANDREW, CONNOLLY, DEREK, DAVEY, PATRICK, SENIOR, ROXY, BIRDI, INDERPAUL, CALVERT, JOHN, DONNELLY, PATRICK, TREVELYAN, JASPER, CARTER, JUSTIN, PEACE, AARON, AUSTIN, DAVID, KUKREJA, NEVILLE, HILTON, THOMAS, SRIVASTAVA, SUNNY, WALSH, RONALD, FIELDS, RONALD, HAKAS, JOSEPH, PORTNAY, EDWARD, GOGIA, HARINDER, SALACATA, ABRAHAM, HUNTER, JOHN J., BACHARACH, J MICHAEL, SHAMMAS, NICOLAS, SURESH, DAMODHAR, SCHNEIDER, RICKY, GURBEL, PAUL, BANERJEE, SUBHASH, GRENA, PAUL, BEDWELL, NOEL, SLOAN, STEPHEN, LUPOVITCH, STEVEN, SONI, ANAND, GIBSON, KATHLEEN, SANGRIGOLI, RENEE, MEHTA, RAJENDRA, I-HSUAN TSAI, PETER, GILLESPIE, EVE, DEMPSEY, STEPHEN, HAMROFF, GLENN, BLACK, ROBERT, LADER, ELLIS, KOSTIS, JOHN B., BITTNER, VERA, MCGUINN, WILLIAM, BRANCH, KELLEY, MALHOTRA, VINAY, MICHAELSON, STEPHEN, VACANTE, MICHAEL, MCCORMICK, MATTHEW, ARIMIE, RALUCA, CAMP, ALAN, DAGHER, GEORGE, KOSHY, N. MATHEW, THEW, STEPHEN, COSTELLO, FREDERICK, HEIMAN, MARK, CHILTON, ROBERT, MORAN, MICHAEL, ADLER, FREDRIC, COMEROTA, ANTHONY, SEIWERT, ANDREW, FRENCH, WILLIAM, SEROTA, HARVEY, HARRISON, ROBERT, BAKAEEN, FAISAL, OMER, SHUAB, CHANDRA, LOKESH, WHELAN, ALAN, BOYLE, ANDREW, ROBERTS-THOMSON, PHILIP, ROGERS, JAMES, CARROLL, PATRICK, COLQUHOUN, DAVID, SHAW, JAMES, BLOMBERY, PETER, AMERENA, JOHN, HII, CHRIS, ROYSE, ALISTAIR, SINGH, BHUWAN, SELVANAYAGAM, JOSEPH, JANSEN, SHIRLEY, LO, WINGCHI, HAMMETT, CHRISTOPHER, POULTER, ROHAN, NARASIMHAN, SESHASAYEE, WIGGERS, HENRIK, NIELSEN, HENRIK, GISLASON, GUNNAR, KOBER, LARS, HOULIND, KIM, BOENELYKKE SOERENSEN, VIBEKE, DIXEN, ULRIK, REFSGAARD, JENS, ZEUTHEN, ELISABETH, SOEGAARD, PETER, HRANAI, MARIAN, GASPAR, LUDOVIT, PELLA, DANIEL, HATALOVA, KATARINA, DROZDAKOVA, ERIKA, COMAN, IOAN, DIMULESCU, DOINA, VINEREANU, DRAGOS, CINTEZA, MIRCEA, SINESCU, CRINA, ARSENESCU, CATALINA, BENEDEK, IMRE, BOBESCU, ELENA, DOBREANU, DAN, GAITA, DAN, IANCU, ADRIAN, ILIESIU, ADRIANA, LIGHEZAN, DANIEL, PETRESCU, LUCIAN, PIRVU, OCTAVIAN, TEODORESCU, IULIA, TESLOIANU, DAN, VINTILA, MARIUS MARCIAN, CHIONCEL, OVIDIU, Anand, Sonia S, Bosch, Jackie, Eikelboom, John W, Connolly, Stuart J, Diaz, Rafael, Widimsky, Peter, Aboyans, Victor, Alings, Marco, Kakkar, Ajay K, Keltai, Katalin, Maggioni, Aldo P, Lewis, Basil S, Störk, Stefan, Zhu, Jun, Lopez-Jaramillo, Patricio, O'Donnell, Martin, Commerford, Patrick J, Vinereanu, Dragos, Pogosova, Nana, Ryden, Lars, Fox, Keith A A, Bhatt, Deepak L, Misselwitz, Frank, Varigos, John D, Vanassche, Thomas, Avezum, Alvaro A, Chen, Edmond, Branch, Kelley, Leong, Darryl P, Bangdiwala, Shrikant I, Hart, Robert G, and Yusuf, Salim
- Published
- 2018
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47. Clinical impact of disinvestment in hydroxyethyl starch for patients undergoing coronary artery bypass surgery: a retrospective observational study
- Author
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Hong, Michael, Jones, Philip M., Martin, Janet, Kiaii, Bob, Arellano, Ramiro, Cheng, Davy, and John-Baptiste, Ava A.
- Published
- 2019
- Full Text
- View/download PDF
48. Early clinical outcomes of a novel self-expanding transapical transcatheter aortic valve bioprosthesis
- Author
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Chu, Michael W.A., Bagur, Rodrigo, Losenno, Katie L., Jones, Philip M., Diamantouros, Pantelis, Teefy, Patrick, Gelinas, Jill J., and Kiaii, Bob
- Published
- 2017
- Full Text
- View/download PDF
49. Hybrid Coronary Revascularization
- Author
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Kiaii, Bob, primary, Giambruno, Vincenzo, additional, Teefy, Patrick, additional, Chu, Michael W.A., additional, and Sridhar, Kumar, additional
- Published
- 2019
- Full Text
- View/download PDF
50. Contributors
- Author
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Agnihotri, Arvind K., primary, Ailawadi, Gorav, additional, Arsalan, Mani, additional, Bajwa, Gurjyot, additional, Baker, Craig J., additional, Bavaria, Joseph E., additional, Bonatti, Johannes, additional, Boodhwani, Munir, additional, Chan, Vincent, additional, Chu, Michael W.A., additional, Coselli, Joseph S., additional, Coyan, Garrett, additional, Dagenais, François, additional, Dahl, Jolian, additional, David, Tirone E., additional, DeNino, Walter F., additional, De Roock, Sophie, additional, Doty, John R., additional, Ehsan, Afshin, additional, El Khoury, Gebrine, additional, Elmistekway, Elsayed, additional, Fortier, Jacqueline H., additional, Ghanta, Ravi K., additional, Giambruno, Vincenzo, additional, Gillinov, A. Marc, additional, Glineur, David, additional, Goldstone, Andrew B., additional, Grau, Juan B., additional, Hang, Dustin, additional, Hasan, Faisal, additional, Hussain, Syed Tarique, additional, Ikonomidis, John S., additional, Javadikasgari, Hoda, additional, Kiaii, Bob, additional, Kim, Won-Keun, additional, Kron, Irving L., additional, Kumar, S. Ram, additional, Lamelas, Joseph, additional, LeMaire, Scott A., additional, Luc, Jessica G.Y., additional, Mangi, Abeel A., additional, Mesana, Thierry G., additional, Mick, Stephanie, additional, Mihaljevic, Tomislav, additional, Moncef, Hlal, additional, Niu, Zhaozhou, additional, Paulsen, Michael J., additional, Pettersson, Gӧsta B., additional, Preventza, Ourania, additional, Prud'Homme, Dominique, additional, Rao, Vivek, additional, Raza, Sajjad, additional, Ribeiro, Igo B., additional, Rodriguez, Maria Lorena, additional, Rubens, Fraser D., additional, Ruel, Marc, additional, Sabik, Joseph F., additional, Schaff, Hartzell V., additional, Sciortino, Christopher, additional, Seki, Hiroshi, additional, Sellke, Frank W., additional, Shemin, Richard Jay, additional, Sodha, Neel R., additional, Soltesz, Edward G., additional, Sridhar, Kumar, additional, Starnes, Vaughn A., additional, Sultan, Ibrahim, additional, Suri, Rakesh M., additional, Szeto, Wilson Y., additional, Taghavi, Sharven, additional, Teefy, Patrick, additional, Toeg, Hadi, additional, Une, Dai, additional, Vlahakes, Gus J., additional, Walther, Thomas, additional, Woo, Y. Joseph, additional, and Wright, Cameron D., additional
- Published
- 2019
- Full Text
- View/download PDF
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