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The current study aimed to evaluate the anti-arthritic effects of a nanocomposite from Cinnamomum zeylanicum, and to further demonstrate its mechanism of action in RA induced RA by Complete Freund's Adjuvant (CFA). and it was diagnosed by atomic force microscopy (AFM) and infrared spectroscopy (FT-IR) revealed the emergence of new diffraction levels for nanocomposites, which clearly indicates the success of the loading process. X-ray evaluation clearly showed the severity of joint deformity according to the extent of osteoarthritis, joint spaces, soft tissue inflammation, subchondral erosion, and articular sclerosis. The immunological results indicated that the induction of rheumatoid arthritis (RF) in male G2 white rats led to a significant (P

The current study aimed to know the protective effect of the aqueous extract of Cinnamon zeylanicum and the free Cinnamon nanocomplex loaded with MTX treatment to reduce the effect of arthritis induced with Complete Freunds (CFA Adjuvant) in male albino rats by studying some changes in immunological and histological parameters. Atomic force microscope (AFM) revealed the appearance of changes in the surface of nanocomposites loaded with treatment. The immunological results indicated that the induction of rheumatoid arthritis (RF) in male white G2 rats led to a significant increase (P

The presented work is conducted to examine the impact of hypercholestrolemic diet on male rabbits’ kidneys. A total of 10 male and adult rabbits have been divided (randomly) into 2 groups (5/group) for three months, while the first group was allowed to ad labium supply and drinking tap water and was termed as the control group (G1). Second group rabbits have orally administrated 1,5% gm of the cholesterol with the diet throughout the 3 months (G2). This work indicated the occurrence related to tissue changes in the kidney tissue compared with the control group.Conclusion: In conclusion, our study showed that the hypercholestrolemic diet at a dose of 1.5% gm caused pathological changes to the kidney tissue such as fatty changes in the tissue, the presence of fatty droplets within the capillary of the glomerulus, inflammatory infiltration of cells in the interstitial tissue of the kidney, cystic expansion of the renal tubules, and addition to the presence of hemorrhage compared to the control group

The current study aimed to evaluate the mechanism of reducing the effect of (RA) after it was induced inmale white rat with a Complete Freund’s Adjuvant (CFA) at TNF-? level by treating Xerogel Nanoparticlesand dexamethasone nanocompounded (Xerogel / Dexa) . The free Xerogel nanoparticle had a surfaceroughness coefficient of 0.327 nm and the total percentage of volumes was 90% less than 130 nm, and theresults also indicated that induced rheumatoid arthritis causes Significant increase (p