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34 results on '"Kim, Seulbi"'

9. Iron‐Chelating Hydroxyketone Ligands Promote Degradation of Fe(III)‐Tannic Acid Nanofilms.

Author

Joo, Hyejin, Kim, Seulbi, Park, Kyungran, Jang, Seong Yoon, Kang, Kyungtae, Kim, Hyungjun, and Park, Ji Hun

Subjects
*STABILITY constants, *TRANSITION metal ions, *TANNINS, *NANOFILMS, *METAL ions
Abstract

Polyphenols form nanofilms with transition metal ions by coordination‐driven assembly. The as‐formed metal‐polyphenol nanofilms can degrade in the presence of chelating ligands that exhibit high stability constant with the nanofilm‐forming metal ions. We have demonstrated the degradation of Fe(III)‐tannic acid nanofilms with hydroxyketone ligands, such as maltol, kojic acid, and deferiprone, which exhibit high availability and excellent cytocompatibility. The concentration screening experiments have been performed with different ligand concentrations ranging from 1 mM–25 mM. It is important to note that only deferiprone degrades Fe(III)‐TA nanofilms even at 1 mM, and it retains the degradation activity at pH 7.4. The characteristic degradation activity of hydroxyketone ligands to Fe(III)‐TA nanofilms may depend upon their pKa value and stability constant. The degradation studies herein are attractive for the development of biomedical applications utilizing metal‐polyphenol nanofilms as a sacrificial template. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Focused Ultrasound as a Novel Non-Invasive Method for the Delivery of Gold Nanoparticles to Retinal Ganglion Cells

Author

Park, Younghoon, primary, Shin, Jaewoo, additional, Park, Junwon, additional, Kim, Seulbi, additional, Park, Ji Hun, additional, Kim, Jaeheung, additional, Kim, Chang Seok, additional, Chang, Jin Woo, additional, Schuurmans, Carol, additional, Aubert, Isabelle, additional, Chang, Won Seok, additional, and Eom, Kyungsik, additional

Published
2024
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24. Draft Genome Sequence of Xylaria grammica EL000614, a Strain Producing Grammicin, a Potent Nematicidal Compound

Author

Park, Sook-Young, primary, Jeon, Jongbum, additional, Kim, Jung A, additional, Jeon, Mi Jin, additional, Yu, Nan Hee, additional, Kim, Seulbi, additional, Park, Ae Ran, additional, Kim, Jin-Cheol, additional, Lee, Yerim, additional, Kim, Youngmin, additional, Choi, Eu Ddeum, additional, Jeong, Min-Hye, additional, Lee, Yong-Hwan, additional, and Kim, Soonok, additional

Published
2021
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28. Resveratrol‐β‐Lactoglobulin Composite Nanocoating by Layer‐by‐Layer Assembly with Fe(III)‐Tannic Acid Complex.

Author

Cho, Yeon Seo, Kim, Seulbi, Kim, Young‐Kwan, Jin, Sung Giu, and Park, Ji Hun

Subjects
*TANNINS, *RESVERATROL, *NANOCOATINGS, *DRUG delivery systems, *NANOFILMS
Abstract

Resveratrol (3,4',5‐trihydroxystilbene) is beneficial to human health due to its diverse biological activities including its anti‐inflammatory and anti‐oxidative effects as confirmed by pharmacokinetic tests. Despite these clinical merits, resveratrol's limited hydrosolubility and chemical vulnerability remain challenging with regard to developing a controlled delivery system with enhanced bioavailability. In this work, we report a resveratrol‐β‐lactoglobulin (R‐BLG) composite nanocoating through a layer‐by‐layer assembly with Fe(III)‐tannic acid nanofilms. The R‐BLG composite nanocoating can be formed in planar and particulate substrates, showing excellent film stability under a broad range of pH values and against enzymatic digestion during a weeklong incubation. We envision that the proteinaceous nanocoating herein could be combined with existing pharmaceutical carrier materials (e. g., microcapsules and nanoparticles) to realize advanced drug delivery systems with an expanded repertoire of hydrophobic drugs. [ABSTRACT FROM AUTHOR]

Published
2021
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33. Draft Genome Sequence of Xylaria grammicaEL000614, a Strain Producing Grammicin, a Potent Nematicidal Compound

Author

Park, Sook-Young, Jeon, Jongbum, Kim, Jung A, Jeon, Mi Jin, Yu, Nan Hee, Kim, Seulbi, Park, Ae Ran, Kim, Jin-Cheol, Lee, Yerim, Kim, Youngmin, Choi, Eu Ddeum, Jeong, Min-Hye, Lee, Yong-Hwan, and Kim, Soonok

Abstract

AbstractAn endolichenic fungus, Xylaria grammicastrain EL000614, showed strong nematicidal effects against plant pathogenic nematode, Meloidogyne incognitaby producing grammicin. We report genome assembly of X. grammicaEL000614 comprised of 25 scaffolds with a total length of 54.73 Mb, N50 of 4.60 Mb, and 99.8% of BUSCO completeness. GC contents of this genome were 44.02%. Gene families associated with biosynthesis of secondary metabolites or regulatory proteins were identified out of 13,730 gene models predicted.

Published
2021
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34. Cover Feature: Hydrogen Bonding‐Based Layer‐by‐Layer Assembly of Nature‐Derived Eggshell Membrane Hydrolysates and Coffee Melanoidins in Single‐Cell Nanoencapsulation (ChemNanoMat 5/2022).

Author

Han, Sang Yeong, Yun, Gyeongwon, Nguyen, Duc Tai, Kang, Eunhye K., Lee, Hojae, Kim, Seulbi, Kim, Beom Jin, Park, Ji Hun, and Choi, Insung S.

Subjects
EGGSHELLS, COFFEE, HYDROGEN
Abstract

Coffee melanoidins, biocompatibility, cytoprotection, eggshell membrane hydrolysates, single-cell nanoencapsulation Keywords: coffee melanoidins; biocompatibility; cytoprotection; eggshell membrane hydrolysates; single-cell nanoencapsulation EN coffee melanoidins biocompatibility cytoprotection eggshell membrane hydrolysates single-cell nanoencapsulation 1 1 1 05/10/22 20220501 NES 220501 B Layer-by-layer (LbL) assembly b of food waste-derived materials, eggshell membrane hydrolysates and coffee melanoidins, is applied to the single-cell nanoencapsulation (SCNE) of I Saccharomyces cerevisiae i . The hydrogen bonding-based LbL process is extremely cytocompatible (viability > 99%), and the cell is protected from external assaults, such as heavy metals and UV-B, after the SCNE. [Extracted from the article]

Published
2022
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