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288 results on '"King, M. T."'

17. International validation of the European Organisation for Research and Treatment of Cancer QLQ‐BRECON23 quality‐of‐life questionnaire for women undergoing breast reconstruction

Author

Winters, Z. E., Afzal, M., Rutherford, C., Holzner, B., Rumpold, G., da Costa Vieira, R. A., Hartup, S., Flitcroft, K., Bjelic‐Radisic, V., Oberguggenberger, A., Panouilleres, M., Mani, M., Catanuto, G., Douek, M., Kokan, J., Sinai, P., King, M. T., Spillane, A., Snook, K., Boyle, F., French, J., Elder, E., Chalmers, B., Kabir, M., Campbell, I., Wong, A., Flay, H., Scarlet, J., Weis, J., Giesler, J., Bliem, B., Nagele, E., del Angelo, N., Andrade, V., Assump¸ão Garcia, D., Bonnetain, F., Kjelsberg, M., William‐Jones, S., Fleet, A., Hathaway, S., Elliott, J., Galea, M., Dodge, J., Chaudhy, A., Williams, R., Cook, L., Sethi, S., Turton, P., Henson, A., Gibb, J., Bonomi, R., Funnell, S., Noren, C., Ooi, J., Cocks, S., Dawson, L., Patel, H., Bailey, L., Chatterjee, S., Goulden, K., Kirk, S., Osborne, W., Harter, L., Sharif, M. A., Corcoran, S., Smith, J., Prasad, R., Doran, A., Power, A., Devereux, L., Cannon, J., Latham, S., Arora, P., Ridgway, S., Coulding, M., Roberts, R., Absar, M., Hodgkiss, T., Connolly, K., Johnson, J., Doyle, K., Lunt, N., Cooper, M., Fuchs, I., Peall, L., Taylor, L., and Nicholson, A.

Published
2018
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28. Minimally Important Differences For Interpreting Eortc Qlq-c30 Scores In Melanoma, Breast Cancer And Head And Neck Cancer Patients On Behalf Of The Eortc Breast, Head And Neck, Melanoma And Quality Of Life Groups

Author

Musoro, Z. J., Coens, C., Fiteni, F., Pogoda, K., Cardoso, F., Tribius, S., Singer, S., Oosting, S., Russell, N., Simon, C., Jean-Pascal, M., Gregoire, N, Velikova, G., King, M. T., Gronvold, M., Cocks, K., Sprangers, M., Eggermont, A., Brandberg, Y., Bottomley, A., and Guided Treatment in Optimal Selected Cancer Patients (GUTS)

Published
2018

31. Minimally important differences for interpreting the EORTC QLQ‐C30 in patients with advanced colorectal cancer treated with chemotherapy.

Author

Musoro, J. Z., Sodergren, S. C., Coens, C., Pochesci, A., Terada, M., King, M. T., Sprangers, M. A. G., Groenvold, M., Cocks, K., Velikova, G., Flechtner, H.‐H., and Bottomley, A.

Subjects
CANCER chemotherapy, COLORECTAL cancer, QUALITY of life, ABSOLUTE value, EXPERIMENTAL design
Abstract

Aim: The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ‐C30) assesses the health‐related quality of life of patients in cancer trials. There are currently no minimally important difference (MID) guidelines for the EORTC QLQ‐C30 for colorectal cancer (CRC). This study aims to estimate MIDs for the EORTC QLQ‐C30 scales in patients with advanced CRC treated with chemotherapy and enrolled in clinical trials. Method: The data were obtained from three published EORTC trials that treated CRC patients using chemotherapy. Potential anchors were selected from clinical variables based on their correlation with EORTC QLQ‐C30 scales. Anchor‐based MIDs for within‐group change and between‐group change were estimated via the mean change method and linear regression, respectively, and summarized using weighted correlation. Distribution‐based MIDs were also examined. Results: Anchor‐based MIDs were determined for deterioration in 8 of the 14 EORTC QLQ‐C30 scales and in 9 scales for improvement, and varied by scale, direction of change and anchor. MIDs for improvement (deterioration) ranged from 6 to 18 (−11 to −5) points for within‐group change and 5 to 15 (−10 to −4) for between‐group change. Summarized MIDs (in absolute values) per scale mostly ranged from 5 to 10 points. Conclusions: These findings have clinical relevance for the interpretation of treatment efficacy and the design of clinical trials by informing sample size requirements. [ABSTRACT FROM AUTHOR]

Published
2020
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39. International validation of the European Organisation for Research and Treatment of Cancer QLQ-BRECON23 quality-of-life questionnaire for women undergoing breast reconstruction

Author

Winters, Z E, primary, Afzal, M, additional, Rutherford, C, additional, Holzner, B, additional, Rumpold, G, additional, da Costa Vieira, R A, additional, Hartup, S, additional, Flitcroft, K, additional, Bjelic-Radisic, V, additional, Oberguggenberger, A, additional, Panouilleres, M, additional, Mani, M, additional, Catanuto, G, additional, Douek, M, additional, Kokan, J, additional, Sinai, P, additional, King, M T, additional, Spillane, A, additional, Snook, K, additional, Boyle, F, additional, French, J, additional, Elder, E, additional, Chalmers, B, additional, Kabir, M, additional, Campbell, I, additional, Wong, A, additional, Flay, H, additional, Scarlet, J, additional, Weis, J, additional, Giesler, J, additional, Bliem, B, additional, Nagele, E, additional, del Angelo, N, additional, Andrade, V, additional, Assump¸ão Garcia, D, additional, Bonnetain, F, additional, Kjelsberg, M, additional, William-Jones, S, additional, Fleet, A, additional, Hathaway, S, additional, Elliott, J, additional, Galea, M, additional, Dodge, J, additional, Chaudhy, A, additional, Williams, R, additional, Cook, L, additional, Sethi, S, additional, Turton, P, additional, Henson, A, additional, Gibb, J, additional, Bonomi, R, additional, Funnell, S, additional, Noren, C, additional, Ooi, J, additional, Cocks, S, additional, Dawson, L, additional, Patel, H, additional, Bailey, L, additional, Chatterjee, S, additional, Goulden, K, additional, Kirk, S, additional, Osborne, W, additional, Harter, L, additional, Sharif, M A, additional, Corcoran, S, additional, Smith, J, additional, Prasad, R, additional, Doran, A, additional, Power, A, additional, Devereux, L, additional, Cannon, J, additional, Latham, S, additional, Arora, P, additional, Ridgway, S, additional, Coulding, M, additional, Roberts, R, additional, Absar, M, additional, Hodgkiss, T, additional, Connolly, K, additional, Johnson, J, additional, Doyle, K, additional, Lunt, N, additional, Cooper, M, additional, Fuchs, I, additional, Peall, L, additional, Taylor, L, additional, and Nicholson, A, additional

Published
2017
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40. Connecting farmer mental health with cow health and welfare on dairy farms using robotic milking systems.

Author

King, M. T. M., Matson, R. D., and DeVries, T. J.

Subjects
DAIRY farm management, DAIRY farms, MILKING, MENTAL health, COWS, AGRICULTURE, MILK proteins, ROBOTIC exoskeletons
Abstract

The objective of this exploratory, preliminary study was to survey dairy farmers using robotic milking systems to better understand their mental health and potential connections to their cow health and welfare. Only farms using robotic milking systems in Ontario, Canada were visited for collection of data on management practices, cow welfare, and milk production and quality. Those farmers also completed an online survey that included validated psychometric scales used to assess resilience, stress, anxiety, and depression; results from 28 farms were analysed. Thirty cows per farm (or 30% for herds > 100 milking cows) were scored for body condition (five-point scale: 1 = thin to 5 = over-conditioned) and lameness (five-point scale: 1 = sound to 5 = lame); cows with a Body Condition Score ≤ 2.5 and lameness score ≥ 4 were defined as under-conditioned and severely lame, respectively. Farmer stress was positively associated with severe lameness prevalence, was greater for females vs males, and was greater for those feeding manually vs using an automated feeder. Anxiety and depression were greater for females vs males, and for those working alone, feeding manually, and with lesser milk protein percentage. Anxiety was also positively associated with the prevalence of severe lameness. Resilience was greater for those with automated feeding systems, but tended to be negatively associated with milk yield per robot and positively associated with milk somatic cell count. This is the first study to identify associations between farmer well-being and cow lameness, udder health, and milk yield. With future research, we can better understand this relationship to improve the well-being of both agricultural animals and their caretakers. [ABSTRACT FROM AUTHOR]

Published
2021
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44. Using a discrete choice experiment to value the QLU-C10D: feasibility and sensitivity to presentation format

Author

Norman, R., primary, Viney, R., additional, Aaronson, N. K., additional, Brazier, J. E., additional, Cella, D., additional, Costa, D. S. J., additional, Fayers, P. M., additional, Kemmler, G., additional, Peacock, S., additional, Pickard, A. S., additional, Rowen, D., additional, Street, D. J., additional, Velikova, G., additional, Young, T. A., additional, and King, M. T., additional

Published
2015
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47. Deviations in behavior and productivity data before diagnosis of health disorders in cows milked with an automated system.

Author

King, M. T. M., Dancy, K. M., LeBlanc, S. J., Pajor, E. A., and DeVries, T. J.

Subjects
*COW diseases, *MILK, *COWS, *MILK yield, *RUMINATION (Digestion), *ANIMAL behavior
Abstract

To explore potential changes in behavior and productivity useful for early detection of health disorders in cows milked with automated milking systems (AMS), we collected longitudinal data throughout lactation of 57 dairy cows housed in a freestall barn with an AMS. Health problems were recorded, including subclinical ketosis (SCK; n = 19), metritis (n = 11), hoof disorders (n = 14), pneumonia (n = 7), and displaced abomasum (DA; n = 5). Data on rumination, activity, milking frequency and yield, and lying behavior were recorded electronically. Using repeated-measures mixed linear regression models, these data were analyzed for the days before the day of diagnosis/treatment (d 0) for each disorder separately, controlling for days in milk and parity. Analyses were performed between the day on which each outcome variable deviated significantly from baseline (up to d −14) and the day before diagnosis (nadir at d −1, before treatment and recovery). Outcomes tested were 3-d rolling averages of milk yield, milking frequency, and AMS supplement intake, in addition to daily rumination time (DRT), body weight, milk temperature, activity (measure of head/neck motion), and 3 lying behavior variables. From d −8, −6, and −5 before diagnosis of DA, SCK, or pneumonia, respectively, DRT declined by 45, 25, and 50 min/d. From d −14 to −1 before diagnosis of hoof disorders, DRT declined by 3 min/d. Body weight declined from d −4 before pneumonia (−14 kg/d) and metritis (−13 kg/d), from d −6 before SCK (−10 kg/d), and from d −5 before hoof disorders (−5 kg/d). Milk yield declined by 4.4 and 4.1 kg/d from d −4 before DA and pneumonia diagnoses, respectively, and by 1.2 kg/d from d −5 before SCK diagnosis. Activity levels declined before diagnosis of DA, pneumonia, SCK, or metritis. Lying behavior changed before diagnosis of DA, pneumonia, or metritis. Our results provide evidence that rumination behavior often deviated before milk yield and that several variables could contribute to earlier or automated identification of disorders. Behavior and productivity changed differently in association with various health disorders, suggesting the potential to distinguish among health problems. These variables merit further investigation in larger studies of cows milked with AMS. [ABSTRACT FROM AUTHOR]

Published
2017
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