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3. Retinoblastoma in Asia: Clinical Presentation and Treatment Outcomes in 2112 Patients from 33 Countries

Author

Kaliki, Swathi, Vempuluru, Vijitha S., Mohamed, Ashik, Abdulqader, Rula Ahmed, Aggarwal, Priyanka, Ahmad, Alia, Akib, Marliyanti Nur Rahmah, Al Mesfer, Saleh A., Al Ani, Mouroge Hashim, Al-Badri, Safaa A.Faraj, Angeles Alcasabas, Ana Patricia, Al-Dahmash, Saad A., Al-Haddad, Christiane, Yahya Al-Hussaini, Hamoud Hodeish, Al-Jadiry, Mazin Faisal, Al-Jumaily, Usama, Alkatan, Hind Manaa, Razzaq Mahmood Al-Mafrachi, Ali Abdul, Samad Majeed Al-Shaheen, Athar Abdul, Al-Shammary, Entissar Hadi, Amiruddin, Primawita Oktarima, Armytasari, Inggar, Astbury, Nicholas John, Atalay, Hatice Tuba, Ataseven, Eda, Atchaneeyasakul, La-ongsri, Balayeva, Ruhengiz, Bascaran, Covadonga, Begimkulova, Ainura Suranovna, Bhaduri, Anirban, Bhat, Sunil, Bhattacharyya, Arpita, Blum, Sharon, Bowman, Richard, Buaboonnam, Jassada, Burton, Matthew J., Caspi, Shani, Chaudhry, Shabana, Chawla, Bhavna, Chen, Wensi, Chuluunbat, Tsengelmaa, Dangboon, Wantanee, Das, Anirban, Das, Pranab, Das, Sima, Du, Yi, Dudeja, Gagan, Eka Sutyawan, I Wayan, Fadoo, Zehra, Faranoush, Mohammad, Foster, Allen, Frenkel, Shahar, Ghassemi, Fariba, Gomel, Nir, Gunasekera, D Sanjeeva, Gündüz, Ahmet K., Gupta, Himika, Gupta, Sanjiv, Gupta, Vineeta, Hamid, Syed Ahmer, Hamzah, Norhafizah, Hasanreisoglu, Murat, Hassan, Shadab, Haydar, Huda Awni, Hongeng, Suradej, Hussein Al-Janabi, Allawi Noor, Islamov, Ziyavuddin, Janjua, Teyyeb Azeem, Jeeva, Irfan, Ji, Xunda, Jo, Dong Hyun, Kantar, Mehmet, Kapelushnik, Noa, Kebudi, Rejin, Keomisy, Jonny, Khan, Zohora Jameela, Khaqan, Hussain Ahmed, Khetan, Vikas, Khodabande, Alireza, Kim, Jeong Hun, Kiratli, Hayyam, Koç, Irem, Kulvichit, Kittisak, Kuntorini, Mayasari Wahyu, Li, Cairui, Li, Kaijun, Limbu, Ben, Liu, ChunHsiu, Lutfi, Delfitri, Mahajan, Amita, Maitra, Puja, Makimbetov, Emil Kojoshovich, Maktabi, Azza M.Y., Manzhuova, Lyazat, Masud, Sidra, Mehrvar, Azim, Menon, Vikas, John V Mercado, Gary, Chandra Mishra, Divyansh Kailash, Mohammad, Mona Tayseer, Mudaliar, Sangeeta Sanjay, Mushtaq, Asma, Nair, Akshay Gopinathan, Natarajan, Sundaram, Nency, Yetty Movieta, Neroev, Vladimir, Nuruddin, Murtuza, Pagarra, Halimah, Palanivelu, Mahesh Shanmugam, Papyan, Ruzanna, Pe'er, Jacob, Polyakov, Vladimir, Qadir, Ali Omer, Qayyum, Seema, Qian, Jiang, Quah, BoonLong, Rahman, Ardizal, Rajkarnikar, Purnima, Ramanjulu, Rajesh, Rashid, Riffat, Rojanaporn, Duangnate, Roy, Soma Rani, Saab, Raya Hamad, Saakyan, Svetlana, Sabhan, Ahmed Hatem, Saiju, Rohit, Sayalith, Phayvanh, Sedaghat, Ahad, Seth, Rachna, Shakoor, Shawkat Ara, Sharma, Manoj Kumar, Siddiqui, Sorath Noorani, Singh, Usha, Singha, Penny, Sitorus, Rita S., Soebagjo, Hendrian D., Sultana, Sadia, Sun, Xiantao, Supriyadi, Eddy, Surukrattanaskul, Supawan, Suzuki, Shigenobu, Tan, Deborah, Tang, Jing, Tashvighi, Maryam, Teh, Kok Hoi, Tehuteru, Edi Setiawan, Thawaba, Abdullah Dahan M., Toledano, Helen, Le Trang, Doan, Tripathy, Devjyoti, Tuncer, Samuray, Unal, Emel, Ushakova, Tatiana L., Usmanov, Rustam, Verma, Nishant, Victor, Andi Arus, Vishnevskia-Dai, Victoria, Wang, Yi-Zhuo, Wangtiraumnuay, Nutsuchar, Riono, Widiarti Pandu, Wiwatwongwana, Atchareeya, Wiwatwongwana, Damrong, Wong, Emily S., Wongwai, Phanthipha, Wu, Si-qi, Xiang, Daoman, Xiao, Yishuang, Xu, Bing, Xue, Kang, Yam, Jason C., Yang, Huasheng, Yaqub, Muhammad Amer, Yarovaya, Vera A., Yarovoy, Andrey A., Ye, Huijing, Yousef, Yacoub Abdallah, Yuliawati, Putu, Zhang, Yi, Zia, Nida, Zondervan, Marcia, Fabian, Ido Didi, and Sthapit, Purnima Rajkarnikar

Published
2024
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8. Single shot echo planar imaging (ssEPI) vs single shot turbo spin echo (ssTSE) DWI of the orbit in patients with ocular melanoma.

Author

Gumeler, Ekim, Parlak, Safak, Yazici, Gozde, Karabulut, Erdem, Kiratli, Hayyam, and Oguz, Kader

Subjects
Adult, Aged, Aged, 80 and over, Diffusion Magnetic Resonance Imaging, Echo-Planar Imaging, Eye Neoplasms, Female, Humans, Male, Melanoma, Middle Aged, Orbit, Prospective Studies, Reproducibility of Results, Signal-To-Noise Ratio, Young Adult
Abstract

OBJECTIVES: Diffusion weighted imaging (DWI) has become important for orbital imaging. However, the echoplanar imaging (EPI) DWI has inherent obstacles due to susceptibility to magnetic field inhomogeneities. We conducted a comparative study assessing the image quality of orbits in a patient cohort with uveal melanoma (UM). We hypothesized that single shot turbo spin echo (ssTSE) DWI would have better image quality in terms of less distortion and artifacts and yield better tissue evaluation compared to ssEPI-DWI. METHODS: ssEPI-DWI and ssTSE-DWI of orbits were obtained from 50 patients with uveal melanoma who were prospectively enrolled in the study. Distortion ratio (DR), signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), diffusion signal properties, and apparent diffusion coefficient (ADC) values were collected and compared between ssEPI-DWI and ssTSE-DWI. Two reviewers evaluated and compared the geometric distortion, susceptibility and ghosting artifacts, resolution, demarcation of ocular mass, and overall quality. RESULTS: A higher DR was found in ssEPI-DWI compared to ssTSE-DWI (p < 0.001). SNR and CNR were lower for the temporal lobe cortex (p ≤ 0.004), but higher for melanoma in ssEPI-DWI than ssTSE-DWI (p ≤ 0.037). Geometric distortion and artifacts were more common in ssEPI-DWI (p < 0.001). Resolution (p ≤ 0.013) and overall quality (p < 0.001) were better in ssTSE-DWI. Ocular masses were demarcated better on ssEPI-DWI (p ≤ 0.002). Significant negative correlations between T1 and T2 signal intensities (r = -0.369, p ≤ 0.008) and positive correlations between T2 and both DWI signal intensities (r = 0.686 and p < 0.001 for ssEPI-DWI, r = 0.747 and p < 0.001 for ssTSE-DWI) were revealed. CONCLUSION: With less geometric distortion and susceptibility artifacts, better resolution, and overall quality, ssTSE-DWI can serve as an alternative to ssEPI-DWI for orbital DWI. ADVANCES IN KNOWLEDGE: ssTSE-DWI can be a better alternative of diffusion imaging of orbits with less susceptibility artifact and geometric distortion compared to ssEPI-DWI.

Published
2021

10. The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries

Author

Fabian, Ido Didi, Abdallah, Elhassan, Abdullahi, Shehu U, Abdulqader, Rula A, Abdulrahaman, Aminatu A, Abouelnaga, Sherif, Ademola-Popoola, Dupe S, Adio, Adedayo, Afifi, Mahmoud A, Afshar, Armin R, Aggarwal, Priyanka, Aghaji, Ada E, Ahmad, Alia, Akib, Marliyanti NR, Akinsete, Adeseye, Al Harby, Lamis, Al Mesfer, Saleh, Al Ani, Mouroge H, Alarcón Portabella, Silvia, Al-Badri, Safaa AF, Alcasabas, Ana Patricia A, Al-Dahmash, Saad A, Alejos, Amanda, Alemany-Rubio, Ernesto, Alfa Bio, Amadou I, Alfonso Carreras, Yvania, Al-Haddad, Christiane E, Al-Hussaini, Hamoud HY, Ali, Amany M, Alia, Donjeta B, Al-Jadiry, Mazin F, Al-Jumaily, Usama, Alkatan, Hind M, All-Eriksson, Charlotta, Al-Mafrachi, Ali ARM, Almeida, Argentino A, Alsawidi, Khalifa M, Al-Shaheen, Athar ASM, Al-Shammary, Entissar H, Amankwaa-Frempong, Doreen, Amiruddin, Primawita O, Armytasari, Inggar, Astbury, Nicholas J, Atalay, Hatice T, Ataseven, Eda, Atchaneeyasakul, La-ongsri, Atsiaya, Rose, Autrata, Rudolf, Balaguer, Julia, Balayeva, Ruhengiz, Barranco, Honorio, Bartoszek, Paulina, Bartuma, Katarina, Bascaran, Covadonga, Bechrakis, Nikolaos E, Beck Popovic, Maja, Begimkulova, Ainura S, Benmiloud, Sarra, Berete, Rokia C, Berry, Jesse L, Bhaduri, Anirban, Bhat, Sunil, Bhattacharyya, Arpita, Biewald, Eva M, Binkley, Elaine, Blum, Sharon, Bobrova, Nadia, Boldt, H.C., Bonanomi, Maria Teresa BC, Bouda, Gabrielle C, Bouguila, Hédi, Brennan, Rachel C, Brichard, Bénédicte G, Buaboonnam, Jassada, Budiongo, Aléine, Burton, Matthew J, Calderón-Sotelo, Patricia, Calle Jara, Doris A, Camuglia, Jayne E, Cano, Miriam R, Capra, Michael, Caspi, Shani, Cassoux, Nathalie, Castela, Guilherme, Castillo, Luis, Català-Mora, Jaume, Cavieres, Isabel, Chandramohan, Arthika, Chantada, Guillermo L, Chaudhry, Shabana, Chawla, Bhavna, Chen, Wensi, Chiwanga, Faraja S, Chuluunbat, Tsengelmaa, Cieslik, Krzysztof, Clark, Antony, Cockcroft, Ruellyn L, Comsa, Codruta, Correa Llano, Maria G, Corson, Timothy W, Couitchere, Line, Cowan-Lyn, Kristin E, Csóka, Monika, Dangboon, Wantanee, Das, Anirban, Das, Pranab, Das, Sima, Davanzo, Jacquelyn M, Davidson, Alan, De Francesco, Sonia, De Potter, Patrick, Quintero D, Karina, Demirci, Hakan, Desjardins, Laurence, Díaz Coronado, Rosdali Y, Dimaras, Helen, Dodgshun, Andrew J, Donato Macedo, Carla R, Dragomir, Monica D, Du, Yi, Du Bruyn, Magritha, Du Plessis, Johannes, Dudeja, Gagan, Eerme, Katrin, Eka Sutyawan, I Wayan, El Kettani, Asmaa, Elbahi, Amal M, Elder, James E, Elhaddad, Alaa M, Elhassan, Moawia MA, Elzembely, Mahmoud M, Ericksen, Connor, Essuman, Vera A, Evina, Ted Grimbert A, Ezegwui, Ifeoma R, Fadoo, Zehra, Fandiño, Adriana C, Faranoush, Mohammad, Fasina, Oluyemi, Fernández, Delia DPG, Fernández-Teijeiro, Ana, Foster, Allen, Frenkel, Shahar, Fu, Ligia D, Fuentes-Alabi, Soad L, Garcia, Juan L, García Aldana, David, Garcia Pacheco, Henry N, Geel, Jennifer A, Ghassemi, Fariba, Girón, Ana V, Goenz, Marco A, Gold, Aaron S, Goldberg, Hila, Gole, Glen A, Gomel, Nir, Gonzalez, Efren, Gonzalez Perez, Graciela, González-Rodríguez, Liudmira, Gorfine, Malka, Graells, Jaime, Gregersen, Pernille A, Grigorovski, Nathalia DAK, Guedenon, Koffi M, Gunasekera, D Sanjeeva, Gündüz, Ahmet K, Gupta, Himika, Gupta, Sanjiv, Gupta, Vineeta, Hadjistilianou, Theodora, Hamel, Patrick, Hamid, Syed A, Hamzah, Norhafizah, Hansen, Eric D, Harbour, J William, Hartnett, M. Elizabeth, Hasanreisoglu, Murat, Muhammad, Hassan, Hassan, Sadiq, Hassan, Shadab, Hautz, Wojciech, Haydar, Huda, Hederova, Stanislava, Hessissen, Laila, Hongeng, Suradej, Hordofa, Diriba F, Hubbard, G. Baker, Hummelen, Marlies, Husakova, Kristina, Hussein Al-Janabi, Allawi N, Ibanga, Affiong, Ida, Russo, Ilic, Vesna R, Islamov, Ziyavuddin, Jairaj, Vivekaraj, Janjua, Teyyeb, Jeeva, Irfan, Ji, Xunda, Jo, Dong Hyun, Jones, Michael M, Kabesha Amani, Theophile B, Kabore, Rolande L, Kaliki, Swathi, Kalinaki, Abubakar, Kamsang, Pius, Kantar, Mehmet, Kapelushnik, Noa, Kardava, Tamar, Kebudi, Rejin, Keomisy, Jonny, Kepak, Tomas, Ketteler, Petra, Khan, Zohora J, Khaqan, Hussain A, Khetan, Vikas, Khodabande, Alireza, Khotenashvili, Zaza, Kim, Jonathan W, Kim, Jeong Hun, Kiratli, Hayyam, Kivela, Tero T., Klett, Artur, Koç, Irem, Kosh Komba Palet, Jess Elio, Krivaitiene, Dalia, Kruger, Mariana, Kulvichit, Kittisak, Kuntorini, Mayasari W, Kyara, Alice, Lam, Geoffrey C, Larson, Scott A, Latinović, Slobodanka, Laurenti, Kelly D, Lavy, Yotam, Lavric Groznik, Alenka, Leverant, Amy A, Li, Cairui, Li, Kaijun, Limbu, Ben, Liu, Chun-Hsiu, Quah, BoonLong, López, Juan P, Lukamba, Robert M, Luna-Fineman, Sandra, Lutfi, Delfitri, Lysytsia, Lesia, Madgar, Shiran, Magrath, George N, Mahajan, Amita, Maitra, Puja, Maka, Erika, Makimbetov, Emil K, Maktabi, Azza, Maldonado, Carlos, Mallipatna, Ashwin, Manudhane, Rebecca, Manzhuova, Lyazat, Martín-Begue, Nieves, Masud, Sidra, Matende, Ibrahim O, Mattosinho, Clarissa CDS, Matua, Marchelo, Mayet, Ismail, Mbumba, Freddy B, McKenzie, John D, Mehrvar, Azim, Mengesha, Aemero A, Menon, Vikas, Mercado, Gary John V, Mets, Marilyn B, Midena, Edoardo, Miller, Audra, Mishra, Divyansh KC, Mndeme, Furahini G, Mohamedani, Ahmed A, Mohammad, Mona T, Moll, Annette C, Montero, Margarita M, Moreira, Claude, Mruthyunjaya, Prithvi, Msina, Mchikirwa S, Msukwa, Gerald, Mudaliar, Sangeeta S, Muma, Kangwa I M, Munier, Francis L, Murray, Timothy G, Musa, Kareem O, Mushtaq, Asma, Musika, Anne A, Mustak, Hamzah, Mustapha, Tajudeen, Muyen, Okwen M, Myezo, Khumo H, Naidu, Gita, Naidu, Natasha, Nair, Akshay Gopinathan, Natarajan, Sundaram, Naumenko, Larisa, Ndoye Roth, Paule Aïda, Nency, Yetty M, Neroev, Vladimir, Ng, Yvonne, Nikitovic, Marina, Nkanga, Elizabeth D, Nkumbe, Henry E, Numbi, Marcel N, Nummi, Kalle, Nuruddin, Murtuza, Nyaywa, Mutale, Nyirenda, Chinsisi, Obono-Obiang, Ghislaine, Oliver, Scott CN, Oporto, Joaquin, Ortega-Hernández, Miriam, Oscar, Alexander H, Ossandon, Diego, Pagarra, Halimah, Paintsil, Vivian, Paiva, Luisa, Palanivelu, Mahesh Shanmugam, Papyan, Ruzanna, Parrozzani, Raffaele, Pascual Morales, Claudia R, Paton, Katherine E, Pe'er, Jacob, Peralta Calvo, Jesús, Perić, Sanja, Pham, Chau TM, Philbert, Remezo, Plager, David A, Pochop, Pavel, Polania, Rodrigo A., Polyakov, Vladimir, Ponce, Jimena, Qadir, Ali O, Qayyum, Seema, Qian, Jiang, Refaeli, David, Rahman, Ardizal, Rajkarnikar, Purnima, Ramanjulu, Rajesh, Ramasubramanian, Aparna, Ramirez-Ortiz, Marco A, Randhawa, Jasmeen K, Randrianarisoa, Hoby Lalaina, Raobela, Léa, Rashid, Riffat, Reddy, M.A., Renner, Lorna A, Reynders, David, Ribadu, Dahiru, Ritter-Sovinz, Petra, Rogowska, Anna, Rojanaporn, Duangnate, Romero, Livia, Roy, Soma R, Saab, Raya H, Saakyan, Svetlana, Sabhan, Ahmed H, Sagoo, Mandeep S, Said, Azza MA, Saiju, Rohit, Salas, Beatriz, San Román Pacheco, Sonsoles, Sánchez, Gissela L, Sanchez Orozco, Alma Janeth, Sayalith, Phayvanh, Scanlan, Trish A, Schlüter, Sabrina, Schwab, Christoph, Sedaghat, Ahad, Seth, Rachna, Sgroi, Mariana, Shah, Ankoor S, Shakoor, Shawkat A, Sharma, Manoj K, Sherief, Sadik T, Shields, Carol L, Sia, David, Siddiqui, Sorath Noorani, Sidi cheikh, Sidi, Silva, Sónia, Singh, Arun D, Singh, Usha, Singha, Penny, Sitorus, Rita S, Skalet, Alison H, Soebagjo, Hendrian D, Sorochynska, Tetyana, Ssali, Grace, Stacey, Andrew W, Staffieri, Sandra E, Stahl, Erin D, Steinberg, David M, Stones, David K, Strahlendorf, Caron, Suarez, Maria Estela Coleoni, Sultana, Sadia, Sun, Xiantao, Superstein, Rosanne, Supriyadi, Eddy, Surukrattanaskul, Supawan, Suzuki, Shigenobu, Svojgr, Karel, Sylla, Fatoumata, Tamamyan, Gevorg, Tan, Deborah, Tandili, Alketa, Tang, Jing, Tarrillo Leiva, Fanny F, Tashvighi, Maryam, Tateshi, Bekim, Teh, Kok Hoi, Tehuteru, Edi S, Teixeira, Luiz F, Tekavcic Pompe, Manca, Thawaba, Abdullah Dahan M, Theophile, Tuyisabe, Toledano, Helen, Trang, Doan L, Traoré, Fousseyni, Tripathy, Devjyoti, Tuncer, Samuray, Tyau-Tyau, Harba, Umar, Ali B, Unal, Emel, Uner, Ogul E, Urbak, Steen F, Ushakova, Tatiana L, Usmanov, Rustam H, Valeina, Sandra, Valente, Paola, van Hoefen Wijsard, Milo, Vasquez Anchaya, Jacqueline Karina, Vaughan, Leon O, Veleva-Krasteva, Nevyana V, Verma, Nishant, Victor, Andi A, Viksnins, Maris, Villacís Chafla, Edwin G, Villegas, Victor M, Vishnevskia-Dai, Victoria, Waddell, Keith, Wali, Amina H, Wang, Yi-Zhuo, Wangtiraumnuay, Nutsuchar, Wetter, Julie, Widiarti, Widiarti, Wilson, Matthew W, Wime, Amelia DC, Wiwatwongwana, Atchareeya, Wiwatwongwana, Damrong, Wolley Dod, Charlotte, Wong, Emily S, Wongwai, Phanthipha, Wu, Si-qi, Xiang, Daoman, Xiao, Yishuang, Xu, Bing, Xue, Kang, Yaghy, Antonio, Yam, Jason C, Yang, Huasheng, Yanga, Jenny M, Yaqub, Muhammad A, Yarovaya, Vera A, Yarovoy, Andrey A, Ye, Huijing, Yee, Roberto I, Yousef, Yacoub A, Yuliawati, Putu, Zapata López, Arturo M, Zein, Ekhtelbenina, Zhang, Yi, Zhilyaeva, Katsiaryna, Zia, Nida, Ziko, Othman AO, Zondervan, Marcia, and Bowman, Richard

Published
2022
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12. The Pediatric and Young Adult Choroidal and Ciliary Body Melanoma Genetic Study, A Survey by the European Ophthalmic Oncology Group

Author

van Poppelen, Natasha M., Cassoux, Nathalie, Turunen, Joni A., Naus, Nicole C., Verdijk, Robert M., Vaarwater, Jolanda, Cohen, Victoria, Papastefanou, Vasilios P., Kiratli, Hayyam, Saakyan, Svetlana V., Tsygankov, Alexander Y., Rospond-Kubiak, Iwona, Mudhar, Hardeep S., Salvi, Sachin M., Kiilgaard, Jens F., Heegaard, Steffen, Moulin, Alexandre P., Saornil, Maria A., Garciá-Alvarez, Ciro, Fili, Maria, Eide, Nils A., Meyer, Peter, Kivela, Tero T., de Klein, Annelies, Kilic, Emine, Al-Jamal, Ranaa T., van Poppelen, Natasha M., Cassoux, Nathalie, Turunen, Joni A., Naus, Nicole C., Verdijk, Robert M., Vaarwater, Jolanda, Cohen, Victoria, Papastefanou, Vasilios P., Kiratli, Hayyam, Saakyan, Svetlana V., Tsygankov, Alexander Y., Rospond-Kubiak, Iwona, Mudhar, Hardeep S., Salvi, Sachin M., Kiilgaard, Jens F., Heegaard, Steffen, Moulin, Alexandre P., Saornil, Maria A., Garciá-Alvarez, Ciro, Fili, Maria, Eide, Nils A., Meyer, Peter, Kivela, Tero T., de Klein, Annelies, Kilic, Emine, and Al-Jamal, Ranaa T.

Abstract

PURPOSE:To explore the genetic background of choroidal and ciliary body melanoma among children and young adults, with special focus on BAP1 germline variants in this age group. METHODS:Patients under the age of 25 and with confirmed choroidal or ciliary body melanoma were included in this retrospective, multicenter observational study. Nuclear BAP1 immunopositivity was used to evaluate the presence of functional BAP1 in the tumor. Next-generation sequencing using Ion Torrent platform was used to determine pathogenic variants of BAP1, EIF1AX, SF3B1, GNAQ and GNA11 and chromosome 3 status in the tumor or in DNA extracted from blood or saliva. Survival was analyzed using Kaplan-Meier estimates. RESULTS:The mean age at diagnosis was 17 years (range 5.0–24.8). A germline BAP1 pathogenic variant was identified in an 18-year-old patient, and a somatic variant, based mainly on immunohistochemistry, in 13 (42%) of 31 available specimens. One tumor had a somatic SF3B1 pathogenic variant. Disomy 3 and the absence of a BAP1 pathogenic variant in the tumor predicted the longest metastasis-free survival. Males showed longer metastasis-free survival than females (P = 0.018). CONCLUSIONS:We did not find a stronger-than-average BAP1 germline predisposition for choroidal and ciliary body melanoma among children and young adults compared to adults. Males had a more favorable survival and disomy 3, and the absence of a BAP1 mutation in the tumor tissue predicted the most favorable metastasis-free survival. A BAP1 germline pathogenic variant was identified in one patient (1%), and a somatic variant based mainly on immunohistochemistry in 13 (42%).

Published
2024

14. Orbital metastasis of choriocarcinoma from a testicular malignant germ cell tumor: A late unfavorable prognostic sign

Author

Kiratli, Hayyam, Agin, Abdullah, Koç, Irem, Akman, Orkun, and Söylemezoglu, Figen

Subjects
Eye cancer -- Case studies -- Diagnosis, Metastasis -- Case studies -- Diagnosis, Testicular cancer -- Case studies -- Complications and side effects, Germ cell tumors -- Case studies -- Complications and side effects, Choriocarcinoma -- Case studies -- Diagnosis, Health
Abstract

Byline: Hayyam. Kiratli, Abdullah. Agin, Irem. Koç, Orkun. Akman, Figen. Söylemezoglu A 43-year-old man presented with a painful left proptosis 6 years after he had had orchiectomy for a mixed [...]

Published
2023

20. International Olympic Committee (IOC) consensus paper on sports-related ophthalmology issues in elite sports

Author

Moe, Morten Carstens, primary, Özmert, Emin, additional, Baudouin, Christophe, additional, Binadra, Abhinav, additional, Crafoord, Sven, additional, Jo, Young, additional, Kiratli, Hayyam, additional, Moore, Melita, additional, Pitsiladis, Yannis P, additional, Rolle, Udo, additional, Tan, Ben, additional, Yanik, Özge, additional, Budgett, Richard, additional, Erdener, Ugur, additional, Steffen, Kathrin, additional, and Engbretsen, Lars, additional

Published
2023
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22. Retinoblastomda Tanısal Yaklaşımlar, Sınıflandırma ve Yönetim.

Author

KIRATLI, Hayyam and KOÇ, İrem

Abstract

Copyright of Current Retina Journal / Güncel Retina Dergisi is the property of Anadolu Kitabevi Basim Yayim Medikal Turizm Kirtasiye Tic. Ltd. Sti. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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23. Nöroblastomun Orbita Metastazında Klinik Bulgular ve Tedaviye Yanıt: Kesitsel Araştırma.

Author

KOÇ, İrem, TOPRAK, Hilal, VARAN, Ali, and KIRATLI, Hayyam

Abstract

Copyright of MN Opthalmology / MN Oftalmoloji is the property of Medical Network and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023

30. Dual ophthalmic arteries: a new case

Author

Arat, Anıl, Kiratli, Hayyam, Varan, Ali, Tatar, Ilkan, Balci, Sinan, Aktas, Hilal Akdemir, Arat, Anıl, Kiratli, Hayyam, Varan, Ali, Tatar, Ilkan, Balci, Sinan, and Aktas, Hilal Akdemir

Abstract

We report one retinoblastoma patient with dual ophthalmic arteries (also known as double ophthalmic arteries) arising from the internal carotid artery which fuse with each other inside the orbit. The caudal ophthalmic artery with larger caliber originated from the cavernous segment of internal carotid artery and passed through the superior orbital fissure. The cranial and tiny one arose more cranially from the supraclinoid internal carotid artery and passed through the optic canal. After superselective catheterization, frank anastomosis was shown between two ophthalmic arteries and the central retinal artery arose from the cranial one. To the best of our knowledge, this case is the first observation of a dual ophthalmic artery with cavernous/supracavernous origins fusing with each other proven by superselective ophthalmic angiography. Whether there is an anastomosis between two ophthalmic arteries is important for deciding which artery to be selected for intraarterial treatment. In cases of retinoblastoma, detailed angiographic analysis may be essential to examine the orbital arterial system and to avoid unexpected complications during intraarterial chemotherapy.

Published
2022

35. sj-pdf-1-jbm-10.1177_03936155221088886 - Supplemental material for Evaluation of HSP-27, BAP1, BRAF V600E, CCR7, and PD-L1 expression in uveal melanoma on enucleated eyes and metastatic liver tumors

Author

Ağın, Abdullah, Kiratli, Hayyam, Guresci, Servet, Babaoglu, Berrin, Karakaya, Jale, and Soylemezoglu, Figen

Subjects
FOS: Clinical medicine, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-pdf-1-jbm-10.1177_03936155221088886 for Evaluation of HSP-27, BAP1, BRAF V600E, CCR7, and PD-L1 expression in uveal melanoma on enucleated eyes and metastatic liver tumors by Abdullah Ağın, Hayyam Kiratli, Servet Guresci, Berrin Babaoglu, Jale Karakaya and Figen Soylemezoglu in The International Journal of Biological Markers

Published
2022
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38. Reaktif Retinal Astrositik Tümörlerde Tedavi ve Takip Sonuçlarımız: Kesitsel Araştırma.

Author

KOÇ, İrem, KIRAĞI, Dila, and KIRATLI, Hayyam

Abstract

Copyright of Türkiye Klinikleri Journal of Ophthalmology is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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45. Adjuvant therapy of histopathological risk factors of retinoblastoma in Europe: A survey by the European Retinoblastoma Group (EURbG)

Author

Dittner‐Moormann, Sabine, primary, Reschke, Madlen, additional, Abbink, Floor C. H., additional, Aerts, Isabelle, additional, Atalay, Hatice Tuba, additional, Fedorovna Bobrova, Nadezhda, additional, Biewald, Eva, additional, Brecht, Ines B., additional, Caspi, Shani, additional, Cassoux, Nathalie, additional, Castela, Guilherme, additional, Diarra, Yelena, additional, Duncan, Catriona, additional, Ebinger, Martin, additional, Garcia Aldana, David, additional, Hadjistilianou, Doris, additional, Kepák, Tomáš, additional, Klett, Artur, additional, Kiratli, Hayyam, additional, Maka, Erika, additional, Opocher, Enrico, additional, Pawinska‐Wasikowska, Katarzyna, additional, Rascon, Jelena, additional, Russo, Ida, additional, Rutynowska‐Pronicka, Olga, additional, Sábado Álvarez, Constantino, additional, Pacheco, Sonsoles San Roman, additional, Svojgr, Karel, additional, Timmermann, Beate, additional, Vishnevskia‐Dai, Vicktoria, additional, Eggert, Angelika, additional, Ritter‐Sovinz, Petra, additional, Bechrakis, Nikolaos E., additional, Jenkinson, Helen, additional, Moll, Annette, additional, Munier, Francis L., additional, Popovic, Maja Beck, additional, Chantada, Guillermo, additional, Doz, François, additional, and Ketteler, Petra, additional

Published
2021
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48. Adjuvant therapy of histopathological risk factors of retinoblastoma in Europe: a survey by the European Retinoblastoma group (EURbG)

Author

Dittner-Moormann, Sabine, primary, Reschke, Madlen, additional, Abbink, Floor, additional, Aerts, Isabelle, additional, Atalay, Hatice, additional, Bobrova, Nadezhda Fedorovna, additional, Biewald, Eva, additional, Brecht, Ines, additional, Caspi, Shani, additional, Cassoux, Nathalie, additional, Castela, Guilherme, additional, Diarra, Yelena, additional, Duncan, Catriona, additional, Ebinger, Martin, additional, Aldana, David Garcia, additional, Hadjistilianou, Theodora, additional, Kepák, Tomáš, additional, Klett, Artur, additional, Kiratli, Hayyam, additional, Maka, Erika, additional, Opocher, Enrico, additional, Rascon, Jelena, additional, Pawińska-Wąsikowska, Katarzyna, additional, Russo, Ida, additional, Rutynowska-Pronicka, Olga, additional, Sábado, Constantino, additional, Pacheco, Sonsoles San Roman, additional, Svojgr, Karel, additional, Timmermann, Beate, additional, Vishnevskia-Dai, Vicktoria, additional, Eggert, Angelika, additional, Ritter-Sovinz, Petra, additional, Bechrakis, Nicolaos, additional, Jenkinson, Helen, additional, Moll, Annette, additional, Munier, Francis, additional, Beck-Popovic, Maja, additional, Chantada, Guillermo, additional, Doz, Francois, additional, and Ketteler, Petra, additional

Published
2020
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