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21 results on '"Kitamura, Isamu"'

9. Incidence of Subacute Sclerosing Panencephalitis Following Measles and Measles Vaccination in Japan.

Author

OKUNO, YOSHIOMI, NAKAO, TOORU, ISHIDA, NAKAO, KONNO, TASUKE, MIZUTANI, HIROMICHI, FUKUYAMA, YUKIO, SATO, TAKESHI, ISOMURA, SHIN, UEDA, SHIGEHARU, KITAMURA, ISAMU, and KAJI, MASARO

Abstract

Okuno Y (Research Institute for microbial Diseases, Osaka University, yamada-oka, Suita, Osaka 565, Japan), Nakao T, Ishida N, Konno T, Mizutani H, Fukuyama Y, Sato T, Isomura S, Ueda S, Kitamura I and Kaji M. Incidence of subacute sclerosing panencephalitis following measles and measles vaccination in Japan. 1989, : 684–689. The Japanese Committee for the National Registry of Subacute Sclerosing Panencephalitis (SSPE) confirmed that 215 cases of SSPE occurred in the 20 years from 1966 to 1985, as discovered in the 10-year surveillance from April 1976 through March 1986. The annual incidence in recent years has been between 10 and 23 cases. Among cases with a certain history of measles illness or measles vaccination, 184 (90.2%) had a history of measles illness without receiving measles vaccine. There were 11 probable measles vaccine-associated cases (5.4%) three (1.5%) being vaccinated with a combined use of killed and live vaccine and eight (3.9%) with further attenuated live vaccine. There were nine cases (4.4%) Without a history of either measles illness or measles vaccination. Intervals between measles illness and the onset of SSPE varied from 1 to 16 years (mean, 7.0 years). The periods following measles vaccination with further attenuated live vaccine were 2 to 11 years (mean, 4.6 years). Annual incidence rates of SSPE per million cases of measles ranged between 6.1 and 40.9 (mean, 16.1) in the 10 measles epidemic years 1968–1977, and those following vaccination with further attenuated live vaccine were zero in most years and at the highest 3.08 (mean, 0.9) per million doses of distributed vaccine. [ABSTRACT FROM PUBLISHER]

Published
1989
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11. Some observations on the outbreak of encepalo-meningornyelitis encountered in Ehime Syuso area through tweenty-eight hospitalized patients (1956)

Author

Kitamura, Isamu

Abstract

An outbreak of encephalomeningomyelitis in Ehime·Syuso area from April to June 1956 was clinico-virologically investigated with the materials obtained from 28 hospitalized cases and their healthy visiting relatives. The major rise in polio type I antibody titer and the positive isolation of 4 strains of type I indicate the epidemy in this area to be the polio type 1. Three undeterminable cytopathogenic agents were concomitantly obtained in the HeLa cultures. The style of this episode was duly compared with the documents already reported.

Published
1957

12. Hyperreactivity of lymphocytes to streptolysin O and lack of plasma inhibitory factor (s) in patients with mucocutaneous lymphnode syndrome

Author

Wakiguchi, Hiroshi, Fujieda, Mikiya, Matsumoto, Kenji, Ohara, Yuji, Wakiguchi, Akiko, Shiraishi, Taisuke, Kurashige, Takanobu, and Kitamura, Isamu

Subjects
mucocutaneous lymphnode syndrome, Adult, DNA Replication, genetic structures, Infant, Mucocutaneous Lymph Node Syndrome, Lymphocyte Activation, eye diseases, Bacterial Proteins, Reference Values, Child, Preschool, Streptolysins, Humans, plasma inhibitory factor (s), sense organs, Lymphocytes, streptolysin O, Child
Abstract

Lymphocyte activation by streptolysin O (SLO) and factors in the plasma which inhibit the response to SLO were examined in 19 patients with mucocutaneous lymphnode syndrome (MCLS), 54 age-matched (6 months-6 years) normal children, 41 normal children older than 6 years and 10 normal adults. In normal children younger than 6 years, the response to SLO was weak and in many cases no response was seen. On the other hand, in the patients with MCLS, the response of lymphocytes to SLO was high and comparable to the response in adults and children older than 6 years. The DNA synthesis of lymphocytes stimulated by SLO was inhibited almost completely by autologous or allogeneic plasma of many of the normal children and adults. The plasma of patients with MCLS did not inhibit, but rather enhanced the response to SLO. These results suggest that the increased response of lymphocytes to SLO and the lack of plasma inhibitory factors in patients with MCLS may be due to the immune response to the pathogen of MCLS, as yet undiscovered.

Published
1986

13. Acrodermatitis Enteropathica

Author

NAGAO, Yo, primary, TAKE, Makoto, additional, HAGIYAMA, Masaharu, additional, KODAMA, Hajime, additional, ARATA, Jiro, additional, KITAMURA, Isamu, additional, and OGURA, Hideo, additional

Published
1978
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