Search

Your search keyword '"Kleine, W."' showing total 222 results
Start Over Author "Kleine, W."
222 results on '"Kleine, W."'

18. Wissenschaftlicher Teil

Author

Albert, P., Pake, C., Rotte, K., Reusch, K., Schulz, K. -D., Zippel, H. H., Doppelfeld, E., Kaiser, R., Albrecht, M., Trams, G., Kleinkauf-Houken, A., Thomsen, K., Kaufmann, M., Drings, P., Queißer, W., Lochbühler, H., Kubli, F., v. Fournier, D., Sievers, H., Wöllgens, P., Nedden, R., Nessler, A., Pfuhl, P. J., Thüre, D., Kuttig, H., Wysocki, S., Heep, J., Blobel, R., Abel, U., Kaufmann, M., Kubli, F., Brunnert, K., v. Fournier, D., Lammers, G., Gammert, D., Abel, U., Audretsch, W., Erdmann, H., zippel, H. H., Crombach, G., Burrenkopf, E., Schmidt-Rhode, P., Schulz, K. -D., Nienhaus, H., Holzgreve, W., Beller, F. K., Klöck, F. -K., Rotthaus, H., Timmermann, J., Audretsch, W., Erdmann, H., Leipoldt, M., Ludovico, M., Bauer, M., von Fournier, D., Kubli, F., zum Winkel, K., Späh, O., Müller, A., Schöndorf, N. K., Gräber, St., Eckel, H., Volk, M., Scheuffele, J., Rossbach, G., Bastert, G., Naujoks, H., Kühn, W., v. Fournier, D., Leppien, G., Müller, A., Rummel, H. H., Dick, G., Koenig, U. D., Erdman, S., Koldovský, U., Hilkens, J., Bender, H. G., v. Matthiessen, H., Hilgers, J., Spielmann, M., Kitschke, H. -J., Tietje, K., Meier, W., Reusch, K., Zippel, H. H., Schulz, K. -D., Würz, H., Kaiser, R., Fuchs, A., Geyer, H., Wittliff, J. L., Pfleiderer, A., Michel, R. -T., Bastert, G., Fortmeyer, H. P., Stegmüller, M., Schmidt-Matthiesen, H., Lapp, C., Bastert, G., Alberts, D. S., Fortmeyer, H. P., Schmidt-Matthiesen, H., Ceschan, R., Fortmeyer, H. P., Bastert, G., Michel, R. -T., Schmidt-Matthiesen, H., Bastert, G., Michel, R. -T., Schmidt-Matthiesen, H., Goebel, R., v. Matthiessen, H., Caffier, H., Kleine, W., Jerabek, R., Daxenbichler, G., Marth, C., Callies, R., Röthig, A., Zeller, G. X., Walz, K. A., Heilmann, L., Kock, U., Simon, W. E., Albrecht, M., Hölzel, F., von Maillot, K., Süssenbach, J., Caffier, H., Albrecht, M., Simon, W. E., Hölzel, F., Ochs, U., Wolnik, L., Eulenburg, R., Schulz, K. -D., Janisch, C. -P., Friedland, R., Knapstein, P. -G., Heberling, D., Wurster, K., Grewe, M., Rieth, J., Rummel, H. H., Schulz, K. -D., Bastert, G., Caffier, H., Zander, J., Pichlmayr, I., Pohl, S., Steude, U., Hirsch, H. A., Klein, H. O., Hettenbach, A., Wiest, W., Kupka, K., Böhme, K., Lohmann, H. U., Behrendt, H., Homann, W., Heilmann, L., Schmidt, E. H., Stening, C., Beller, F. K., Bender, H. G., Beck, L., Eulenburg, R., Ochs, U., Wolnik, L., Schulz, K. -D., Henschler, D., Kreienberg, R., Melchert, F., Feige, A., Rose, E., Haubitz, I., Albert, P., Gille, J., Burkert, W., Hilfrich, J., Weitzel, H. K., Majewski, A., Horner, G., Caffier, H., Brandau, H., Schmidt-Rhode, P., Schulz, K. -D., Wolnik, L., Würz, H., Sturm, G., Melchert, F., Kreienberg, R., Crombach, G., Würz, H., Schmidt-Rhode, P., Zippel, H. H., Werner, A., Matzanke, L., Seegert, B., Schuster, E., Wellmann, H., Krebs, D., Bichler, A., Fuchs, D., Hausen, A., Hetzel, H., Reibnegger, G., Wachter, H., Nauth, H. F., Herzog, R. E., Kleine, W., Stange, S., Dagy, D., Ladner, H. -A., Hillemanns, H. G., Bauknecht, T., Meerpohl, H. G., and Bauknecht, T

Published
1983
Full Text
View/download PDF

23. Combined Tamoxifen and Luteinizing Hormone-Releasing Hormone (LHRH) Agonist Versus LHRH Agonist Alone in Premenopausal Advanced Breast Cancer: A Meta-Analysis of Four Randomized Trials

Author

Klijn, J. G. M., Blamey, R. W., Boccardo, F., Tominaga, T., Duchateau, L., Sylvester, R., Beex, L. V. A. M., Mauriac, L., Zijl, J. A., Veyret, C., Wildiers, J., Jassem, J., Piccart, M., Burghouts, J., Becqaert, D., Seynaeve, C., Mignolet, F., Namer, M., Julien, J. P., Garcia Conde, J., Dunser, M., Margreiter, R., Tjabbes, T., Roozendaal, K. J., Velden, P. C., Nortier, J. W. R., Blamey, R., Howell, A., Forbes, J., Kaufmann, M., Nordenskjold, B., Kvinnsland, S., Wilson, R. G., Jonat, W., Kleeberg, U. R., Eiermann, W., Hilfrich, J., Weitzel, H. K., Glas, U., Rutqvist, L. E., Rudenstam, C., Sander, S., Ryden, S., Honsson, P., Lonning, P. E., Loven, L., Russell, I. S., Olweny, C., Byrne, J. J., Snyder, R. D., Coates, A. S., Lowenthal, R. M., Jeal, P. N., Dalley, D. N., Janicke, F., Kleine, W., Michel, R. Th, Canobbio, L., Amoroso, D., Rubagotti, A., Bumma, C., D Aprile, M., Matteis, A., Di Carlo, A., Francini, G., Petrioli, R., Folco, U., Calligioni, E., Gallotti, P., Lopez, M., Mesiti, M., Pacini, P., Sassi, M., Sismondi, P., Paolo Zola, Ogita, M., Okazaki, M., Watanabe, T., Satomi, T., Hatazawa, C., Okuyama, N., Koyama, T., Kobayashi, M., Shimizu, T., Tabei, T., Sano, M., Makino, H., Ando, J., Kimura, M., Takeuchi, T., Aoyama, H., Koyama, H., Shin, E., Chou, G., and Medical Oncology

Subjects
Agonist, Oncology, endocrine system, Cancer Research, medicine.medical_specialty, Neoplasms, Hormone-Dependent, Antineoplastic Agents, Hormonal, medicine.drug_class, medicine.medical_treatment, Antineoplastic Agents, Breast Neoplasms, Buserelin, Gonadotropin-Releasing Hormone, Drug Therapy, SDG 3 - Good Health and Well-being, Neoplasms, Internal medicine, medicine, Humans, Neoplasm Metastasis, Hormone-Dependent, Randomized Controlled Trials as Topic, Hormonal, business.industry, Standard treatment, Goserelin, Oophorectomy, Cancer, Antiestrogen, medicine.disease, Survival Analysis, Drug Therapy, Combination, Female, Premenopause, Tamoxifen, Endocrinology, Combination, business, hormones, hormone substitutes, and hormone antagonists, medicine.drug
Abstract

PURPOSE: The logic behind the application of luteinizing hormone-releasing hormone (LHRH) agonists in combination with tamoxifen in premenopausal women is that LHRH agonists on the one hand suppress the tamoxifen-induced stimulation of the pituitary-ovarian function and, on the other hand, seem as effective as surgical castration. This meta-analysis combines all randomized evidence to compare the combined treatment with LHRH agonist alone with respect to overall survival, progression-free survival, and objective response in premenopausal women with advanced breast cancer. PATIENTS AND METHODS: Four clinical trials randomizing a total of 506 premenopausal women with advanced breast cancer to LHRH agonist alone or to the combined treatment of LHRH agonist plus tamoxifen were identified. Meta-analytic techniques were used to analyze individual patient data from these trials. RESULTS: With a median follow-up of 6.8 years, there was a significant survival benefit (stratified log-rank test, P = .02; hazards ratio [HR] = 0.78) and progression-free survival benefit (stratified log-rank test, P = .0003; HR = 0.70) in favor of the combined treatment. The overall response rate was significantly higher on combined endocrine treatment (stratified Mantel Haenszel test, P = .03; odds ratio = 0.67). CONCLUSION: The combination of LHRH agonist plus tamoxifen is superior to LHRH agonist alone in premenopausal women with advanced breast cancer. Therefore, if a premenopausal woman with advanced breast cancer is thought to be suitable for endocrine treatment, it is proposed that the combination of a LHRH agonist plus tamoxifen be considered as the new standard treatment.

Published
2001
Full Text
View/download PDF

24. Indications and Route of Hysterectomy for Benign Diseases. Guideline of the DGGG, OEGGG and SGGG (S3 Level, AWMF Registry No. 015/070, April 2015)

Author

Neis, K., additional, Zubke, W., additional, Römer, T., additional, Schwerdtfeger, K., additional, Schollmeyer, T., additional, Rimbach, S., additional, Holthaus, B., additional, Solomayer, E., additional, Bojahr, B., additional, Neis, F., additional, Reisenauer, C., additional, Gabriel, B., additional, Dieterich, H., additional, Runnenbaum, I., additional, Kleine, W., additional, Strauss, A., additional, Menton, M., additional, Mylonas, I., additional, David, M., additional, Horn, L-C., additional, Schmidt, D., additional, Gaß, P., additional, Teichmann, A., additional, Brandner, P., additional, Stummvoll, W., additional, Kuhn, A., additional, Müller, M., additional, Fehr, M., additional, and Tamussino, K., additional

Published
2016
Full Text
View/download PDF

25. Moderatorenbericht Früherkennung des Endometriumcarcinoms

Author

Mestwerdt, W., Dallenbach-Hellweg, G., Hohlweg-Majert, P., Lahousen, M., Locher, G. W., Müller, H. A., Peters-Welte, C., Pickel, H., Schneider, M. L., Soost, H. J., Tauber, P. F., von Holst, T., Klinga, K., Runnebaum, B., Huber, H., Kucera, H., Kleine, W., Geyer, H., Gille, J., Albert, P., Bacman, O., Haute, V., Schneider, M. L., Czekelius, P., Feichter, G. E., Höffken, H., Heep, J., Haag, D., Heberling, D., Brandt, H., Rummel, H., Ortner, A., Liebenstein, J., Dallenbach-Hellweg, G., Hettenbach, A., Lalik, J., Noack, E. J., Öhlinger, W., Goldhofer, W., Wharton, J. T., Hersh, E. M., Haas, W., Wolnik, L., Slenczka, W., Kürzl, R., Chen, J. Y., Lohen, K. J., Baltzer, J., Zander, J., Denzler, U., Heinzl, S., Baltzer, J., Lohe, K. J., Köpcke, W., Zander, J., Breinl, H., Meinen, K., Reitzenstein, M., Tulusan, A. H., Egger, H., Knapstein, P., Hager, S., Kutzner, J., Friedberg, V., Bauer, M., von Fournier, D., Weisleder, R., zum Winkel, K., Kubli, F., Kucera, H., Gerstner, G., Weghaupt, K., Bilek, K., Manzl, J., Hetzenauer, A., Goebel, R., von Wrese, D., Deutschle, R., Meerpohl, H. G., v. Röder, S., Pfleiderer, A., Fabinger, R., Klöpfer, K., Lietz, H., Franz, G., Martin, K., Jekel, E., Franz, G., Lietz, H., Stein, G., Szalay, S., Szepesi, T., Breitenecker, G., Schratter-Sehn, A. U., Rogan, A., Janisch, H., Sarembe, B., Richter, P., Hilfrich, J., Kühnle, H., Burkert, W., Majewski, A., Frischkorn, R., Stoll, P., Buchholz, F., Semm, K., Rogan, A. M., Schieder, K., Bieglmayer, Ch., Breitenecker, G., Szalay, S., Janisch, H., Schmidt-Matthiesen, A., Schweikhart, G., Hoffmann, G., Grill, H. J., Manz, B., Poloow, K., Geyer, H., de Gregorio, G., Teufel, G., Caffier, H., Horner, G., Mestwerdt, W., Bauknecht, T., and Meerpohl, H. -G.

Published
1983
Full Text
View/download PDF

42. P96 Randomized trials to assess the effectivity of tamoxifen as adjuvant treatment in node-negative and receptor positive breast cancer. The Heidelberg II and GABG II trials

Author

von Minckwitz, G., primary, Kaufmann, M., additional, Schmid, H., additional, Kleine, W., additional, Brunnert, K., additional, Ulmer, M.U., additional, Stosiek, U., additional, Mahlke, M., additional, Mehrpohl, H.G., additional, Ne ses, M., additional, and Baltzer, J., additional

Published
1998
Full Text
View/download PDF

43. P82 Comparison of doxorubicin/cyclophosphamide versus doxorubicin/cyclophosphamide/tamoxifen and CMF-chemotherapy versus tamoxifen in node positve breast cancer. An up-date of the German adjuvant breast cancer group (GABG) trial

Author

Kaufmann, I.M., primary, Jonat, W., additional, von Minckwitz, G., additional, Schmid, H., additional, Kleine, W., additional, Melchert, F., additional, Ulmer, M.U., additional, Stosiek, U., additional, Trams, G., additional, Balzer, J., additional, and Caffier, H., additional

Published
1998
Full Text
View/download PDF

50. Moderatorenbericht Früherkennung des Endometriumcarcinoms.

Author

Mestwerdt, W., Dallenbach-Hellweg, G., Hohlweg-Majert, P., Lahousen, M., Locher, G., Müller, H., Peters-Welte, C., Pickel, H., Schneider, M., Soost, H., Tauber, P., Holst, T., Klinga, K., Runnebaum, B., Huber, H., Kucera, H., Kleine, W., Geyer, H., Gille, J., and Albert, P.

Abstract

Copyright of Archives of Gynecology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
1984
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results