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1. Breast Disease

Author

Hussain, Tasadooq, Kneeshaw, Peter, Wong, Kenneth, editor, Walton, Shernaz, editor, Sudhakaran, Simi, editor, and Cookson, John, editor

Published
2023
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2. HER2-enriched subtype and novel molecular subgroups drive aromatase inhibitor resistance and an increased risk of relapse in early ER+/HER2+ breast cancer

Author

Evans, Abigail, Ball, Adrian, Johri, Akhil, Nejim, Ali, Jones, Alison, Corder, Allan, Thorne, Amanda, Anand, Ambika, Chakrabarti, Amitabha, Robinson, Anne, Skene, Anthony, Modi, Anupam, Patel, Ashraf, Kothari, Ashutosh, McFall, Brendan, Mortimer, Caroline, Lee, Caroline, Chan, Charlie, Abson, Charlotte, Holcombe, Christopher, Hinton, Christopher, Hollywood, Ciaran, Murphy, Claire, Crowley, Clare, Harding-Mackean, Claudia, Griffith, Clive, Lewanski, Conrad, Rea, Daniel, Hwang, David, Crawford, Derek, Thekkinkattil, Dinesh, Ferguson, Douglas, Adamson, Douglas, Wheatley, Duncan, Ravichandran, Duraisamy, Babu, Ed, Hyett, Elaine, Ashkanani, Fawzia, Hoar, Fiona, Kenny, Frances, Dyke, Gary, Sparrow, Geoffrey, Gilbert, Cunnick, Giles, Algurafi, Hafiz, Sweetland, Helen, Prof, Highes-Davies, Hamed, Hisham, Smith, Ian, Laidlaw, Ian, Khattak, Ilyas, Newby, Jacqueline, Rees-Lee, Jacqueline, Kokan, Jalal, Barrett, Jane, Naik, Jay Dolatrai, Vaidya, Jayant, Forrest, Jennifer, Parmar, Jitendra, Adams, Jocelyn, Fox, John, Roberts, Jonathan, Dawson, Jonathan, Doughty, Julie, Donnelly, Jull, Dunn, Kathleen, Chin, Kian, Horgan, Kieran, Thakur, Kislaya, Barthelmes, Ludger, Wyld, Lynda, Bhattacharyya, Madhumita, Hadaki, Maher, Kishore, Makam, Ornstein, Marcus, Bramley, Maria, Bews-Hair, Maria, Parton, Marina, Sibbering, Mark, Kissin, Mark, Churn, Mark, Hogg, Martin, Quigley, Mary, Hatton, Matthew, Winter, Matthew, Adelekan, Matthew, Shere, Michael, Carr, Michael, Williams, Michael, Absar, Mohammed, Sharif, Muhammad, Kelleher, Muireann, Walji, Nawaz, Williams, Nicholas, Gallegos, Nicholas, Bundred, Nigel, Hatcher, Olivia, Crellin, Perric, Crane, Peter, Donnelly, Peter, Kneeshaw, Peter, Walker, Philip, Sinha, Prakash, Bhaskar, Pudhupalayam, Soulsby, Racheal, Todd, Radha, Vidya, Raghavan, Mehra, Rakesh, Prasad, Ramachandran, Cutress, Ramsay, Sharma, Ravi, Roylance, Rebecca, Goranova, Rebecca, Salman, Reem Ramzi, Bonom, Riccardo, Johnson, Richard, Sutton, Richard, Linforth, Rick, Coleman, Rob, Grieve, Robert, Leonard, Robert, Reichert, Robert, Kennedy, Robert, Agarwal, Roshan, Allerton, Rozenn, Burcombe, Russell, Davis, Ruth, Narayanan, Sankaran, Chandrasekharan, Sankaran, Vesty, Sarah, Seetharam, Seema, Ledwidge, Serena, Iqbal, Shabana, Wahee, Shamaela, Silva, Shobha, Pain, Simon, Holt, Simon, Thomson, Simon, Smith, Simon, Ellenbogen, Simon, Laws, Siobhan, Chan, Stephen, Johnston, Stephen, Holt, Steve, Thrush, Steven, McIntosh, Stuart, Chatterjee, Sumohan, Cleator, Susan, Usman, Tamoor, Johnson, Tayo, Kovacs, Tibor, Irvine, Tracey, Barthkur, Urmila, Pope, Vanessa, Brown, Victoria Alexandra, Muralikrishna, Vummiti, Samra, Walid, Maxwell, William, Winters, Zoe, Bergamino, Milana A., López-Knowles, Elena, Morani, Gabriele, Tovey, Holly, Kilburn, Lucy, Schuster, Eugene F., Alataki, Anastasia, Hills, Margaret, Xiao, Hui, Holcombe, Chris, Robertson, John F., Smith, Ian E., Bliss, Judith M., Dowsett, Mitch, and Cheang, Maggie C.U.

Published
2022
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3. Beliefs About Medication and Uptake of Preventive Therapy in Women at Increased Risk of Breast Cancer: Results From a Multicenter Prospective Study

Author

Adamson, Vanessa, Ainsworth, Sarah, Akerlund, Malin, Baker, Ivanna, Barwell, Julian, Beesley, Jayne, Brock, Lisa, Butcher, Chrissie, Carpenter, Janice, Clark, Martyn, Cocks, Shirley, Conteh, Veronica, Coulding, Martina, Darby, Sue, Duckworth, Angela, Evans, Gareth, Fensom, Catherine, Fletcher, Julie, Foster, Kate, Grieg, Sara, Gullaksen, Elaine, Gurasashvili, Jana, Hardstaff, Lisa, Hart, Rachel, Hoare, Kathryn, Hoffman, Jonathan, Holcombe, Christopher, Horton, Lynne, Howell, Antony, Islam, Farah, Jenkinson, Emma, Jewers, Karen, Joshi, Manisha, Kirkby, Amy, Kneeshaw, Peter, Knife, Natalie, Kokan, Jalal, Li, Jin, Lunt, Nicola, Macmillan, Douglas, Makinson, Karen, Mallidis, Evangelos, Manyangadze, Sarah, Masvaure, Charity, Mistry, Raksha, Ngumo, Alice, Ooi, Jane, Patel, Ashraf, Pope, Vanessa, Price, Laura, Rabson, Fiona, Richardson, Lisa, Ridgway, Stephanie, Riley, Karen, Roberts, Lorraine, Ryan-Smith, Janet, Salih, Vian, Scott, Nicky, Shere, Mike, Sloan, Andrew, Solanky, Nita, Taylor, Amanda, Thekkinkattil, Dinesh, Thomas, Heather, Thorat, Mangesh, Townley, Barbara, Vaidya, Jayant S., Wagstaff, Lynda, Walsh, Shane, Waring, Lynsey, Watterson, Donna, Westley, Charlotte, Wilkinson, Lesley, Willis, Nicola, Wiseman, Julia, Thorneloe, Rachael Jane, Horne, Rob, Side, Lucy, Wolf, Michael Scott, and Smith, Samuel George

Published
2019
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7. Pre-NACT staging in breast cancer: Are they needed in all?

Author

Bichoo, Raouef Ahmed, primary, Elahi, Mohammad Bilal, additional, Ihsan, Naila Bint, additional, Khalifa, Eiman, additional, Srinivasan, Hithashree, additional, Dumitru, Dorin, additional, Mahapatra, Tapan, additional, Wooler, Brendan, additional, Kneeshaw, Peter, additional, and Grover, Kartikae, additional

Published
2023
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16. Abstract PS1-55: Clipping of involved axillary lymph nodes before Neo adjuvant chemotherapy may improve in identification rates & staging of axilla in breast cancer

Author

Elahi, Mohammad Bilal, primary, Bichoo, Raouef Ahmed, additional, Grover, Kartikae, additional, Khalifa, Eiman, additional, Ihsan, Naila Bint, additional, Kneeshaw, Peter J, additional, Wooler, Brendan Paul, additional, Dumitru, Dorin, additional, Roychaudhury, Ronjabati, additional, Rahman, Ayesha, additional, and Mahapatra, Tapan Kumar, additional

Published
2021
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17. Therapeutic mammaplasty is a safe and effective alternative to mastectomy with or without immediate breast reconstruction

Author

Potter, S, primary, Trickey, A, additional, Rattay, T, additional, O'Connell, R L, additional, Dave, R, additional, Baker, E, additional, Whisker, L, additional, Skillman, J, additional, Gardiner, M D, additional, Macmillan, R D, additional, Holcombe, C, additional, Potter, S, additional, Barnes, Nicola L P, additional, Blazeby, Jane, additional, Conroy, Elizabeth, additional, Dave, Rajiv V, additional, Gardiner, Matthew D, additional, Harnett, Adrian, additional, Holcombe, Chris, additional, Potter, Shelley, additional, Rattay, Tim, additional, Skillman, Joanna, additional, Williamson, Paula, additional, Achuthan, Rajgopal, additional, Aggarwal, Shweta, additional, Baker, Elizabeth, additional, Basu, Naren, additional, Brock, Lisa, additional, Fairbrother, Patricia, additional, Ives, Charlotte, additional, Jain, Abhilash, additional, Kim, Baek, additional, Macmillan, R Douglas, additional, Murphy, John, additional, Remoundos, Dennis, additional, Sutton, Richard, additional, Trickey, Adam, additional, Turton, Philip, additional, Williams, Kathryn, additional, Curnier, Alain, additional, Tadros, Amir, additional, Depasquale, Ivan, additional, Fuller, Mairi, additional, Bourne, Roger, additional, Heys, Steven, additional, Hamo, Ishrak, additional, Aloraifi, Fatima, additional, Fopp, Laura, additional, Bali, Radhika, additional, Bache, Sarah, additional, Benyon, Sarah L, additional, Irwin, Michael S, additional, Agrawal, Amit, additional, Malata, Charles M, additional, Murphy, Claire, additional, Misky, Adam, additional, Chicken, Dennis Wayne, additional, Abdullah, Nassreen, additional, Hill, Arnold D K, additional, Cullinane, Carolyn, additional, Irwin, Gareth, additional, McIntosh, Stuart A, additional, Refsum, Sigi, additional, Sloan, Samantha, additional, Mallon, Peter, additional, Sirianni, Chiara, additional, Khattak, Ilyas, additional, Nagachandra, Geerthan, additional, Kiruparan, Pasupathy, additional, Debanth, Debasish, additional, Davey, Simon, additional, Curran, Terry-Ann, additional, Svenning, Matilda, additional, Govindarajulu, Sasirekha, additional, Rayter, Zenon, additional, Ainsworth, Rachel, additional, Cawthorn, Simon, additional, Sahu, Ajay, additional, Wilson, Sherif, additional, Prousskaia, Elena, additional, Accurso, Antonello, additional, Rocco, Nicola, additional, Di Micco, Rosa, additional, Limite, Gennaro, additional, Ceccarino, Raffaele, additional, Liccardo, Raffaele, additional, Coco, Guido, additional, Nizamoglu, Metin, additional, Morgan, Mary, additional, Ramakrishnan, Venkat, additional, Catanuto, Giuseppe, additional, Wilkins, Alex, additional, McManus, Penelope, additional, Kneeshaw, Peter, additional, Grover, Kartikae, additional, Mahapatra, Tapan, additional, Wooler, Brendan, additional, Elahi, Bilal, additional, Ihsan, Naila, additional, Bucknor, Alexandra, additional, Reissis, Dimitris, additional, Hunter, Judith, additional, Wood, Simon, additional, Jallali, Navid, additional, Henry, Francis P, additional, Verjee, Liaquat S, additional, Lee, Jason, additional, Khan, Shazia M, additional, Azmy, Iman, additional, Massey, Julia, additional, Hollywood, Ciaran, additional, Oluwajana, Michael, additional, Bathla, Sonia, additional, Seward, Joanna, additional, Harding-MacKean, Claudia, additional, Lane, Risha, additional, Murali, Kothandaraman, additional, Biswas, Bashishta, additional, Trapszo, Pawel, additional, Seetharam, Seema, additional, Kennedy, Katy, additional, Alder, Louise, additional, Graja, Tomasz, additional, Amin, Khalid, additional, Kokan, Jalal, additional, Roshanlall, Chandeena, additional, Gill, Emma, additional, Kulkarni, Dhananjay, additional, Dixon, J M, additional, Young, Oliver, additional, Saleem, Talha, additional, Biddle, M, additional, Kearns, Marie, additional, Weiler-Mithoff, Eva, additional, Chew, Ben, additional, Malyon, Andy, additional, Scott, John, additional, McGill, David, additional, Mackay, Iain, additional, Bains, Salena, additional, Barrows, Sara, additional, Pilgrim, Simon, additional, Shokuhi, Sheila, additional, Lambert, Kelly, additional, Kenny, Frances, additional, Valassiadou, Kalliope, additional, Kaushik, Monika, additional, Krupa, Jaroslaw, additional, Dragoumis, Dimitris, additional, Lampropoulos, Pavlos, additional, Moss, Sarah, additional, Khalil, Haitham, additional, Haq, Anwar, additional, Balasubramanian, Balapathiran, additional, Charalampoudis, Petros, additional, Hamed, Hisham, additional, Kothari, Ashutosh, additional, Kovacs, Tibor, additional, Douek, Michael, additional, Mehmood, Iftikhar, additional, Ray, Biswajit, additional, Adelekan, Matthew, additional, Humphreys, Laura, additional, Tayeh, Salim, additional, Choy, Christina, additional, Parvanta, Laila, additional, Michieletto, Silvia, additional, Saibene, Tania, additional, O'Brien, James, additional, Down, Sue, additional, Downey, Sarah, additional, Pereira, Jerome, additional, Sami, A S, additional, Gvaramadze, Anzors, additional, Jibril, Jibril A, additional, Thekkinkattil, Dinesh, additional, Udayasankar, S, additional, Khawaja, Saira, additional, Shariaha, Yousef, additional, Holt, Simon, additional, James, Ruth, additional, Rizki, Hirah, additional, Kirkpatrick, Katharine, additional, Ravichandran, Duraisamy, additional, Shrestha, Deepak, additional, Barua, Ellora, additional, Akolekar, Deepika, additional, Hamad, Ahmed, additional, Kleidi, Eleftheria, additional, Hignett, Susan, additional, Pope, Vanessa, additional, Naseem, Salma, additional, Isherwood, Jennifer, additional, Soulsby, Rachel, additional, Taylor, Amanda, additional, Chin, Kian, additional, Nguyen, Dai, additional, Guest, Francesca, additional, Thorne, Amanda, additional, Lefemine, Valentina, additional, Kirchhoff, Chris, additional, Murphy, Declan C, additional, Lo, Michelle, additional, Harcourt, Ruth, additional, Pain, Simon J, additional, Hussien, Maged I, additional, Zechmeister, Katalin, additional, Sassoon, E M, additional, Figus, Andrea, additional, Haywood, Richard M, additional, Ali, Rozina, additional, Alexander, Susanna, additional, Geropantas, Konstantinos, additional, Epurescu, Daniel, additional, Lewis, Rebecca, additional, Fafemi, Oladapo, additional, Gahir, Jasdeep, additional, Gandamihardja, Tasha, additional, Kelsall, Jennett, additional, Muhibullah, Nazli, additional, Otieno, Charlene, additional, Mazari, Fayyaz, additional, Dauria, Marta, additional, Whisker, Lisa, additional, Macmillan, Douglas, additional, Gutteridge, Eleanor, additional, Rasheed, Tuabin, additional, Khout, Hazem, additional, Asgeirsson, Kristjan, additional, McCulley, Stephen, additional, Mariniello, Maria Donatella, additional, Roncella, Manuela, additional, Ghilli, Matteo, additional, Colizzi, Livio, additional, Rossetti, Elena, additional, Marzia, Lo Russo, additional, Fustaino, Loredana, additional, Li, Alessandro Quattrini, additional, Harvey, Kate L, additional, Windle, Rebecca, additional, Remoundos, Dionysios Dennis, additional, Roy, Pankaj, additional, MacLean, Gael, additional, Adwani, Asha, additional, Popa, Elena, additional, Goh, Steven, additional, Shetty, Geeta, additional, Clark, Sarah, additional, Bernaudo, Lorenzo, additional, Agrawal, Avi, additional, Mansfield, Lucy, additional, Tebbal, Sally, additional, Patel, Ashraf, additional, Grassi, Veronica, additional, Pujji, Ojas, additional, Hamnett, Kathryn, additional, Granger, Emily, additional, Durbar, Michael, additional, Pikoulas, Panagiotis, additional, Garnsey, Clare, additional, Walker, Philip, additional, Vollermere, Angela J, additional, Michalakis, Ioannis, additional, Jones, Robin, additional, Youssef, Mina, additional, Masood, Mohammad, additional, Dunn, Julie, additional, Olsen, Sisse, additional, Ferguson, Douglas, additional, Tillett, Rachel, additional, Allan, Anna, additional, Woollard, Alex, additional, Canny, Rebecca, additional, Woollard, Alexander, additional, Mosahebi, Afshin, additional, Hamilton, Stephen, additional, Chana, Jagdeep, additional, Sojitra, Nilesh, additional, Younis, Ibby, additional, Rainsbury, Dick, additional, Chand, Natalie, additional, Kalles, Vasileios, additional, Stebbing, Anne, additional, Harris, Kevin, additional, Laws, Siobhan, additional, Tansley, Anne, additional, Mitchell, Geraldine, additional, de Sousa, Emma, additional, Henderson, Julia, additional, Chandrashekar, Mysore, additional, Pereira, Bernadette, additional, Constantinou, Chloe, additional, Elfadl, Dalia, additional, Irakleidis, Foivos, additional, Hernan, Izaro, additional, Byrne, Miriam, additional, O'Connell, Rachel, additional, Rusby, Jennifer, additional, Barry, Peter, additional, Krupa, Katerine, additional, Allum, William, additional, MacNeill, Fiona, additional, Roche, Nicola, additional, Gui, Gerald, additional, Ramsey, Kelvin, additional, Harris, Paul, additional, James, Stuart, additional, McIntosh, Jamie, additional, Laurence, Nicola, additional, MacLennan, Louise, additional, Milligan, Robert, additional, Cain, Henry, additional, Critchley, Adam, additional, O'Donoghue, Joe, additional, Kalra, Loraine, additional, Collis, Nick, additional, Weston-Petrides, Gina, additional, Fiddes, Roanne, additional, Brown, Victoria, additional, Aertssen, Anna, additional, Slade-Sharman, Diana, additional, Khan, Mansoor, additional, McGuiness, Caroline, additional, Amorosi, Vittoria, additional, di Pompeo Fabio, Santanelli, additional, Exarchos, Georgios, additional, Jiwa, Natasha, additional, Hu, Jennifer, additional, Ledwidge, Serena, additional, Johnson, Laura, additional, Peel, Anthony, additional, Dhooma, Naseem, additional, Farrell, Eric, additional, Devane, Liam, additional, Tevlin, Ruth, additional, McDermott, Enda, additional, Prichard, Ruth, additional, Evoy, Denis, additional, Rothwell, Jane, additional, Geraghty, James, additional, Morrison, Colin, additional, Lawlor, Catriona, additional, Langlands, Fiona, additional, Taylor, Lauren, additional, Achuthan, Raj, additional, Horgan, Kieran, additional, Mckenzie, Shireen, additional, Hogan, Brian, additional, Lansdown, Mark, additional, Navin, Channegowda, additional, Sherwin, Liz, additional, Mortimer, Caroline, additional, Garg, Neeraj, additional, Adam, Rahma, additional, Arif, Tahera, additional, Kryjak, Zbigniew, additional, Ali, Deedar, additional, Sowdi, Ravi, additional, Fage, Elena, additional, Mylvaganam, Senthurun, additional, Matey, Pilar, additional, Vidya, Raghavan, additional, Sircar, Tapan, additional, Asaad, Oubida, additional, Bhaskar, Pud, additional, Dordea, Matei, additional, Chrysafi, Ada, additional, McCartan, Damian, additional, Dave, Rajiv, additional, Foster, Rachel, additional, Wilson, Rebecca, additional, Okwemba, Sylvia, additional, Majeed, Yousef, additional, O'Brien, Ciara, additional, Mathen, Vinod, additional, Barnes, Nicola, additional, Gandhi, Ashu, additional, Harvey, James, additional, Kirwan, Cliona C, additional, Johnson, Richard, additional, Patel, Krupali, additional, Ribas, Maria Dalmau, additional, Vigneswaran, Natali, additional, Challoner, Tom, additional, Park, Alan, additional, Rizkalla, Maged, additional, Tomlins, Abigail, additional, McEvoy, Kat, additional, Jafferbhoy, Sadaf, additional, Soumian, Soni, additional, Narayanan, Sankaran, additional, Kirby, Robert, additional, Bajrusevic, Sladana, additional, Maalo, Joseph, additional, Charalambous, Michalis, additional, Lai, Lee Min, additional, Chong, Kelvin, additional, Thomson, Simon, additional, Monib, Sherif, additional, Chagla, Leena, additional, Audisio, Riccardo, additional, Taghizadeh, Rieka, additional, Iqbal, Azhar, additional, James, Karen, additional, Callaghan, Maria, additional, Poonawala, Shabbir, additional, Lund, Jonathan, additional, Vinayagam, Raman, additional, Thrush, Steven, additional, Thomas, Rachel Bright, additional, Mullan, Michelle, additional, Taylor, Jevan, additional, Yoshimura, Ryo, additional, Mathew, Tom, additional, Jones, Ben Mancey, additional, Munot, Kailas, additional, Nasr, Rana, additional, Piper, Jenny, additional, El-Sharief, Deena, additional, Mustafa, Mohammed, additional, MacLeod, Caitlin, additional, Smyth, Elizabeth, additional, Saeed, Nina, additional, Masannat, Yazan, additional, Mohd-Amin, Amir Tan, additional, Sloan, Sam, additional, McIntosh, Stuart, additional, Ibrahim, Abdulla, additional, Rathinaezhil, Rathi, additional, Khalifa, Eiman, additional, McManus, Penny, additional, Leeper, Alexander, additional, McIlhenny, Jennifer, additional, Mansell, James, additional, Ogsto, Keith, additional, Romics, Laszlo, additional, Shokuhi, Shelia, additional, Lee, Xiang Wei Jonathan, additional, Al-Allak, Asmaa, additional, Fowler, Clare, additional, Massey, Eleanore, additional, Court, Fiona, additional, Hunt, Richard, additional, Vestey, Sarah, additional, Elgammal, Mohsen, additional, Noshirwani, Arish, additional, Arif, Tehera, additional, Syed, Farah H, additional, Safdar, Gazalla, additional, El-Abbar, Mohammed, additional, Hogg, Fiona, additional, McGee, Pauline, additional, Pitsinis, Vassilis, additional, Smith, Jenny, additional, Makkiyah, Sundus, additional, Mustafa, Syed, additional, Photiou, Dana, additional, Gutteridge, Ellie, additional, Oni, Georgette, additional, Hallam, Kelly, additional, Asgeirron, Kristjan, additional, D'Auria, Marta, additional, Al-zubaidi, Samim, additional, Bailey, James, additional, Tenovici, Alexandra, additional, Remoundos, Dionysios-Dennis, additional, Chaidos, Nikos, additional, Predescu, Oana, additional, Rezulski, Jan, additional, Abdullah, Tholkifl, additional, Udayasankar, Sujatha, additional, Talbot, Adam, additional, Singh, Jagdeep, additional, Smith, Amy, additional, Volleamere, Angela, additional, Dean, Sarah, additional, Peiris, Lashan, additional, Sjokvist, Olivia, additional, De Sousa, Emma, additional, Micha, Aikaterini, additional, Godden, Amy, additional, Krupa, Katherine, additional, Henton, John, additional, Bennett, Ruth, additional, Nicholson, Stewart, additional, Paolini, Guido, additional, Renzi, Luca Francesco, additional, Di Pompeo, Santanelli, additional, Ria, Vitto, additional, Lewis, Rebecca S, additional, Hadad, Sirwan, additional, Sharma, Anup, additional, Toomey, Delia, additional, Banerjee, Dibyesh, additional, Tang, Sarah Shuk Kay, additional, McKenzie, Shireen, additional, Ahmad, Tanvir, additional, Williams, Kate, additional, Absar, Mohammed, additional, Nasir, Nabila, additional, Rychlik, Igor Jerzy, additional, Darragh, Lynn, additional, Johnston, Ruth, additional, Kirk, Stephen, additional, Rees-Lee, Jacqueline, additional, Green, Michael, additional, Sharma, Abhishek, additional, Choong, Jia, additional, Ullah, Zaker, additional, Koshy, Ommen, additional, Kiernan, Tamara, additional, Bhojwani, Ajay Ashok, additional, Bright-Thomas, Rachel, additional, Byrne, Ged, additional, Ibrahim, Ibrahim, additional, Highton, Lyndsey, additional, Morris, Owen, additional, Chatterjee, Sumohan, additional, Kirwan, Cliona, additional, Mancey-Jones, Ben, additional, El Sharief, Denna, additional, and Frame, Richard, additional

Published
2020
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18. The impact of immediate breast reconstruction on the time to delivery of adjuvant therapy: the iBRA-2 study

Author

O'Connell, Rachel L, Rattay, Tim, Dave, Rajiv V, Trickey, Adam, Skillman, Joanna, Barnes, Nicola LP, Gardiner, Matthew, Harnett, Adrian, Potter, Shelley, Holcombe, Chris, Blazeby, Jane, Conroy, Elizabeth, O'Brien, Ciara, Williamson, Paula, Curnier, Alain, Tadros, Amir, Depasquale, Ivan, Masannat, Yazan A, Smyth, Elizabeth, Fuller, Mairi, Bourne, Roger, Heys, Steven, Hamo, Ishrak, Aloraifi, Fatima, Fopp, Laura, Bali, Radhika, Bache, Sarah, Benyon, Sarah L, Irwin, Michael S, Agrawal, Amit, Malata, Charles M, Murphy, Claire, Misky, Adam, Chicken, Dennis Wayne, Abdullah, Nassreen, Hill, Arnold DK, Cullinane, Carolyn, Irwin, Gareth, McIntosh, Stuart A, Refsum, Sigi, Sloan, Samantha, Mallon, Peter, Sirianni, Chiara, Khattak, Ilyas, Nagachandra, Geerthan, Kiruparan, Pasupathy, Debanth, Debasish, Davey, Simon, Curran, Terry-Ann, Svenning, Matilda, Govindarajulu, Sasirekha, Rayter, Zenon, Ainsworth, Rachel, Cawthorn, Simon, Sahu, Ajay, Wilson, Sherif, Prousskaia, Elena, Accurso, Antonello, Rocco, Nicola, Di Micco, Rosa, Limite, Gennaro, Ceccarino, Raffaele, Liccardo, Raffaele, Coco, Guido, Nizamoglu, Metin, Morgan, Mary, Ramakrishnan, Venkat, Catanuto, Giuseppe, Wilkins, Alex, McManus, Penelope, Kneeshaw, Peter, Grover, Kartikae, Mahapatra, Tapan, Wooler, Brendan, Elahi, Bilal, Ihsan, Naila, Bucknor, Alexandra, Reissis, Dimitris, Hunter, Judith, Wood, Simon, Jallali, Navid, Henry, Francis P, Verjee, Liaquat S, Lee, Jason, Khan, Shazia M, Azmy, Iman, Massey, Julia, Hollywood, Ciaran, Oluwajana, Michael, Bathla, Sonia, Seward, Joanna, Harding-MacKean, Claudia, Lane, Risha, Murali, Kothandaraman, Biswas, Bashishta, Trapszo, Pawel, Seetharam, Seema, Kennedy, Katy, Alder, Louise, Graja, Tomasz, Amin, Khalid, Kokan, Jalal, Roshanlall, Chandeena, Gill, Emma, Kulkarni, Dhananjay, Dixon, JM, Young, Oliver, Saleem, Talha, Biddle, M, Kearns, Marie, Weiler-Mithoff, Eva, Chew, Ben, Malyon, Andy, Scott, John, McGill, David, Mackay, Iain, Bains, Salena, Barrows, Sara, Pilgrim, Simon, Shokuhi, Sheila, Lambert, Kelly, Kenny, Frances, Valassiadou, Kalliope, Kaushik, Monika, Krupa, Jaroslaw, Dragoumis, Dimitris, Ain, Quratul, Lampropoulos, Pavlos, Moss, Sarah, Khalil, Haitham, Haq, Anwar, Balasubramanian, Balapathiran, Charalampou-Dis, Petros, Hamed, Hisham, Kothari, Ashutosh, Kovacs, Tibor, Douek, Michael, Mehmood, Iftikhar, Ray, Biswajit, Adelekan, Matthew, Humphreys, Laura, Tayeh, Salim, Choy, Christina, Parvanta, Laila, Michieletto, Silvia, Saibene, Tania, O'Brien, James, Down, Sue, Downey, Sarah, Pereira, Jerome, Sami, AS, Gvaramadze, Anzors, Jibril, Jibril A, Thekkinkattil, Dinesh, Udayasankar, S, Khawaja, Saira, Shariaha, Yousef, Holt, Simon, James, Ruth, Rizki, Hirah, Kirkpatrick, Katharine, Ravichandran, Duraisamy, Shrestha, Deepak, Barua, Ellora, Akolekar, Deepika, Hamad, Ahmed, Kleidi, Eleftheria, Hignett, Susan, Pope, Vanessa, Naseem, Salma, Isherwood, Jennifer, Soulsby, Rachel, Taylor, Amanda, Chin, Kian, Nguyen, Dai, Guest, Francesca, Thorne, Amanda, Kirchhoff, Chris, Murphy, Declan C, Lo, Michelle, Harcourt, Ruth, Pain, Simon J, Hussien, Maged I, Zechmeister, Katalin, Sassoon, EM, Figus, Andrea, Haywood, Richard M, Ali, Rozina, Alexander, Susanna, Geropantas, Konstantinos, Epurescu, Daniel, Lewis, Rebecca, Fafemi, Oladapo, Gahir, Jasdeep, Gandamihardja, Tasha, Kelsall, Jennett, Muhibullah, Nazli, Otieno, Charlene, Mazari, Fayyaz, Dauria, Marta, Whisker, Lisa, Macmillan, Douglas, Gutteridge, Eleanor, Rasheed, Tuabin, Khout, Hazem, Asgeirsson, Kristjan, McCulley, Stephen, Mariniello, Maria Donatella, Roncella, Manuela, Ghilli, Matteo, Colizzi, Livio, Rossetti, Elena, Marzia, Lo Russo, Fustaino, Loredana, Li, Alessandro Quattrini, Harvey, Kate L, Windle, Rebecca, Remoundos, Dionysios Dennis, Roy, Pankaj, MacLean, Gael, Adwani, Asha, Popa, Elena, Goh, Steven, Shetty, Geeta, Clark, Sarah, Bernaudo, Lorenzo, Agrawal, Avi, Mansfield, Lucy, Tebbal, Sally, Patel, Ashraf, Grassi, Veronica, Pujji, Ojas, Hamnett, Kathryn, Basu, Naren, Granger, Emily, Durbar, Michael, Pikoulas, Panagiotis, Garnsey, Clare, Walker, Philip, Vollermere, Angela J, Michalakis, Ioannis, Jones, Robin, Youssef, Mina, Ives, Charlotte, Masood, Mohammad, Dunn, Julie, Olsen, Sisse, Ferguson, Douglas, Tillett, Rachel, Allan, Anna, Woollard, Alex, Canny, Rebecca, Woollard, Alexander, Mosahebi, Afshin, Hamilton, Stephen, Ghali, Shadi, Marsh, Daniel, Chana, Jagdeep, Sojitra, Nilesh, Younis, Ibby, Rainsbury, Dick, Chand, Natalie, Kalles, Vasileios, Stebbing, Anne, Harris, Kevin, Laws, Siobhan, Tansley, Anne, Mitchell, Geraldine, de Sousa, Emma, Henderson, Julia, Chandrashekar, Mysore, Pereira, Bernadette, Constantinou, Chloe, Elfadl, Dalia, Irakleidis, Foivos, Hernan, Izaro, Byrne, Miriam, To, Natalie, O'Connell, Rachel, Rusby, Jennifer, Barry, Peter, Krupa, Katerine, Allum, William, MacNeill, Fiona, Roche, Nicola, Gui, Gerald, Ramsey, Kelvin, Harris, Paul, James, Stuart, Power, Kieran, Sutton, Richard, McIntosh, Jamie, Laurence, Nicola, MacLennan, Louise, Milligan, Robert, Cain, Henry, Critchley, Adam, O'Donoghue, Joe, Kalra, Loraine, Collis, Nick, Weston-Petrides, Gina, Fiddes, Roanne, Brown, Victoria, Aertssen, Anna, Slade-Sharman, Diana, Khan, Mansoor, McGuiness, Caroline, Amorosi, Vittoria, Fabio, Santanelli di Pompeo, Exarchos, Georgios, Jiwa, Natasha, Hu, Jennifer, Ledwidge, Serena, Johnson, Laura, Peel, Anthony, Dhooma, Naseem, Farrell, Eric, Devane, Liam, Tevlin, Ruth, McDermott, Enda, Prichard, Ruth, Evoy, Denis, Rothwell, Jane, Geraghty, James, Morrison, Colin, Lawlor, Catriona, Langlands, Fiona, Taylor, Lauren, Turton, Philip, Achuthan, Raj, Horgan, Kieran, Mckenzie, Shireen, Hogan, Brian, Lansdown, Mark, Navin, Channegowda, Sherwin, Liz, Mortimer, Caroline, Garg, Neeraj, Adam, Rahma, Arif, Tahera, Kryjak, Zbigniew, Ali, Deedar, Sowdi, Ravi, Fage, Elena, Mylvaganam, Senthurun, Matey, Pilar, Vidya, Raghavan, Sircar, Tapan, Asaad, Oubida, Bhaskar, Pud, Dordea, Matei, Chrysafi, Ada, McCartan, Damian, Dave, Rajiv, Foster, Rachel, Wilson, Rebecca, Okwemba, Sylvia, Majeed, Yousef, Mathen, Vinod, Murphy, John, Barnes, Nicola, Gandhi, Ashu, Harvey, James, Kirwan, Cliona C, Johnson, Richard, Patel, Krupali, Ribas, Maria Dalmau, Vigneswaran, Natali, Challoner, Tom, Park, Alan, Rizkalla, Maged, Tomlins, Abigail, McEvoy, Kat, Jafferbhoy, Sadaf, Soumian, Soni, Narayanan, Sankaran, Kirby, Robert, Bajrusevic, Sladana, Maalo, Joseph, Charalambous, Michalis, Lai, Lee Min, Chong, Kelvin, Thomson, Simon, Monib, Sherif, Chagla, Leena, Audisio, Riccardo, Taghizadeh, Rieka, Iqbal, Azhar, James, Karen, Callaghan, Maria, Poonawala, Shabbir, Lund, Jonathan, Vinayagam, Raman, Thrush, Steven, Thomas, Rachel Bright, Mullan, Michelle, Taylor, Jevan, Yoshimura, Ryo, Mathew, Tom, Jones, Ben Mancey, Munot, Kailas, Nasr, Rana, Piper, Jenny, El-Sharief, Deena, Mustafa, Mohammed, Dumitru, Dorin, Christopoulos, Petros, O'Leary, Peter, Athanasiou, Irene, Johns, Neil, Mehta, Disha, Bibi, Saira, Syed, Farah, Koris, Jacob, Healy, Samuel, Shanks, Lindsay, Oliver, James, Bucata, Claudiu, Clarke, Natalie, Bignell, Kym, Akerlund, Malin, Brock, Lisa, Hallam, Kelly, Howes, Rachel, Armstrong, Alexander, Sethu, Claire, Zeidan, Bashar, Sjokvist, Olivia, Tasoulis, Marios, Sundaramoorthy, Souganthy, Harris, Chad, Wintrip, Dorothy, Lymperopoulos, N, Jain, Yogesh, Balata, Safa Ahmed, Grp, iBRA-2 Steering, and Collab, Breast Reconstruction Res

Subjects
Adult, Cancer Research, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Mammaplasty, trainee collaboratives, Breast Neoplasms, Article, Cohort Studies, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Breast cancer, breast cancer, Adjuvant therapy, cohort study, Medicine, Humans, Prospective Studies, Prospective cohort study, Mastectomy, Aged, Cancer, Aged, 80 and over, Manchester Cancer Research Centre, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, adjuvant therapy, immediate breast reconstruction, Middle Aged, medicine.disease, Surgery, Radiation therapy, Oncology, Centre for Surgical Research, Chemotherapy, Adjuvant, Outcomes research, 030220 oncology & carcinogenesis, Surgical oncology, Female, Breast reconstruction, business, Complication, Cohort study
Abstract

Background: Immediate breast reconstruction (IBR) is routinely offered to improve quality-of-life for women requiring mastectomy, but there are concerns that more complex surgery may delay adjuvant oncological treatments and compromise long-term outcomes. High-quality evidence is lacking. The iBRA-2 study aimed to investigate the impact of IBR on time to adjuvant therapy.Methods: Consecutive women undergoing mastectomy ± IBR for breast cancer July–December, 2016 were included. Patient demographics, operative, oncological and complication data were collected. Time from last definitive cancer surgery to first adjuvant treatment for patients undergoing mastectomy ± IBR were compared and risk factors associated with delays explored.Results: A total of 2540 patients were recruited from 76 centres; 1008 (39.7%) underwent IBR (implant-only [n = 675, 26.6%]; pedicled flaps [n = 105,4.1%] and free-flaps [n = 228, 8.9%]). Complications requiring re-admission or re-operation were significantly more common in patients undergoing IBR than those receiving mastectomy. Adjuvant chemotherapy or radiotherapy was required by 1235 (48.6%) patients. No clinically significant differences were seen in time to adjuvant therapy between patient groups but major complications irrespective of surgery received were significantly associated with treatment delays.Conclusions: IBR does not result in clinically significant delays to adjuvant therapy, but post-operative complications are associated with treatment delays. Strategies to minimise complications, including careful patient selection, are required to improve outcomes for patients.

Published
2019
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19. Beliefs About Medication and Uptake of Preventive Therapy in Women at Increased Risk of Breast Cancer: Results From a Multicenter Prospective Study

Author

Thorneloe, Rachael Jane, Horne, Rob, Side, Lucy, Wolf, Michael Scott, Smith, Samuel George, Adamson, Vanessa, Ainsworth, Sarah, Akerlund, Malin, Baker, Ivanna, Barwell, Julian, Beesley, Jayne, Brock, Lisa, Butcher, Chrissie, Carpenter, Janice, Clark, Martyn, Cocks, Shirley, Conteh, Veronica, Coulding, Martina, Darby, Sue, Duckworth, Angela, Evans, Gareth, Fensom, Catherine, Fletcher, Julie, Foster, Kate, Grieg, Sara, Gullaksen, Elaine, Gurasashvili, Jana, Hardstaff, Lisa, Hart, Rachel, Hoare, Kathryn, Hoffman, Jonathan, Holcombe, Christopher, Horton, Lynne, Howell, Antony, Islam, Farah, Jenkinson, Emma, Jewers, Karen, Joshi, Manisha, Kirkby, Amy, Kneeshaw, Peter, Knife, Natalie, Kokan, Jalal, Li, Jin, Lunt, Nicola, Macmillan, Douglas, Makinson, Karen, Mallidis, Evangelos, Manyangadze, Sarah, Masvaure, Charity, Mistry, Raksha, Ngumo, Alice, Ooi, Jane, Patel, Ashraf, Pope, Vanessa, Price, Laura, Rabson, Fiona, Richardson, Lisa, Ridgway, Stephanie, Riley, Karen, Roberts, Lorraine, Ryan-Smith, Janet, Salih, Vian, Scott, Nicky, Shere, Mike, Sloan, Andrew, Solanky, Nita, Taylor, Amanda, Thekkinkattil, Dinesh, Thomas, Heather, Thorat, Mangesh, Townley, Barbara, Vaidya, Jayant S, Wagstaff, Lynda, Walsh, Shane, Waring, Lynsey, Watterson, Donna, Westley, Charlotte, Wilkinson, Lesley, Willis, Nicola, and Wiseman, Julia

Abstract

Introduction\ud Uptake of preventive therapies for breast cancer is low. We examined whether women at increased risk of breast cancer can be categorized into groups with similar medication beliefs, and whether belief group membership was prospectively associated with uptake of preventive therapy.\ud \ud Patients and Methods\ud Women (n = 732) attending an appointment to discuss breast cancer risk were approached; 408 (55.7%) completed the Beliefs About Medicines and the Perceived Sensitivity to Medicines questionnaires. Uptake of tamoxifen at 3 months was reported in 258 (63.2%). The optimal number of belief groups were identified using latent profile analysis.\ud \ud Results\ud Uptake of tamoxifen was 14.7% (38/258). One in 5 women (19.4%; 78/402) reported a strong need for tamoxifen. The model fit statistics supported a 2-group model. Both groups held weak beliefs about their need for tamoxifen for current and future health. Group 2 (38%; 154/406 of the sample) reported stronger concerns about tamoxifen and medicines in general, and stronger perceived sensitivity to the negative effects of medicines compared with group 1 (62%; 252/406). Women with low necessity and lower concerns (group 1) were more likely to initiate tamoxifen (18.3%; 33/180) than those with low necessity and higher concerns (group 2) (6.4%; 5/78). After adjusting for demographic and clinical factors, the odds ratio was 3.37 (95% confidence interval, 1.08-10.51; P = .036).\ud \ud Conclusion\ud Uptake of breast cancer preventive therapy was low. A subgroup of women reported low need for preventive therapy and strong medication concerns. These women were less likely to initiate tamoxifen. Medication beliefs are targets for supporting informed decision-making.

Published
2019

21. Xanthogranulomatous inflammation involving latissimus dorsi donor site and implant breast reconstruction: case report and literature review

Author

Hussain Tasadooq, Elahi Bilal, Long Ervine, Mahapatra Tapan, McManus Penelope L, and Kneeshaw Peter J

Subjects
Surgery, RD1-811, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Xanthogranulomatous inflammation is a rare clinico-pathological condition involving many organ systems. Breast involvement with this rare condition reported from a few cases of mastitis has been limited to only microscopic involvement on histology. We would like to report an unusual presentation of this inflammatory process presenting as a solid lump mimicking malignancy in latissimus dorsi donor site scar and implant-based breast reconstruction as a result of a ruptured silicone gel implant. To our knowledge there have been no previous reports on similar presentation published in the literature. This case highlights a rare complication of a leaked silicone gel implant triggering a xanthomatous response in the absence of the usual infective or obstructing etiologies. This condition is of benign nature with complete clearance on surgical excision and excellent clinical prognosis reported from other organ involvement.

Published
2012
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22. Gastric obstruction secondary to metastatic breast cancer: a case report and literature review

Author

Hussain Tasadooq, Elahi Bilal, McManus Penelope, Mahapatra Tapan, and Kneeshaw Peter

Subjects
Medicine
Abstract

Abstract Introduction Gastrointestinal tract soft tissues metastasis is a well-known occurrence with invasive lobular breast cancer subtypes. Gastric involvement is more common, with reports of both diffuse and localized involvements. Usually, a gastric localized involvement presents as wall thickening with an appearance similar to that of a gastrointestinal stromal tumour; rarely does a localized metastatic deposit grow aggressively to present as a large tumour causing obstructive symptoms. Our case highlights one such unusual presentation in a patient presenting with non-specific gastrointestinal symptoms. To the best of our knowledge, there have been no previous reports on a similar presentation occurring from a localized metastasis. Case presentation A 65-year-old Caucasian woman awaiting an outpatient oral gastroduodenoscopy for symptoms of intermittent vomiting, epigastric pains and weight loss of six weeks’ duration presented acutely with symptoms of haematemesis and abdominal distension. An initial contrast-enhanced computed tomography scan showed a grossly dilated stomach with a locally advanced stenosing tumour mass at the pylorus. Our patient had a history of left mastectomy and axillary clearance followed by adjuvant endocrine therapy for an oestrogen receptor- and progesterone receptor-positive, grade 2, invasive lobular breast cancer. The oral gastroduodenoscopy confirmed the computed tomography findings; biopsies of the pyloric mass on immunohistochemistry stains were strongly positive for pancytokeratin and gross cystic disease fluid proteins, consistent with an invasive lobular breast cancer metastasis. She received a palliative gastrojejunal bypass and her adjuvant endocrine treatment was switched over to exemestane. Conclusion Our case highlights the aggressive behaviour of a localized gastric metastasis that is unusual and unexpected. Gastrointestinal symptomatology can be non-specific and, at times, non-diagnostic on conventional mucosal biopsies. A high index of clinical suspicion in patients with a previous history of invasive lobular breast cancer can aid in an early diagnosis and treatment. A combined treatment approach with chemoendocrine therapies achieves remission and improves patient survival.

Published
2012
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23. A digital breast service: Turning myth to reality

Author

Wilkins, Alex, primary, Elahi, Bilal, additional, Ihsan, Naila, additional, Khalifa, Eiman, additional, Wooler, Brendan, additional, McManus, Penelope, additional, Mahapatra, Tapan, additional, Kneeshaw, Peter, additional, and Grover, Kartikae, additional

Published
2018
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24. Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): A double-blind, randomised controlled trial

Author

Forbes, John F, Sestak, Ivana, Howell, Anthony, Bonanni, Bernardo, Bundred, Nigel, Levy, Christelle, von Minckwitz, Gunter, Eiermann, Wolfgang, Neven, Patrick, Stierer, Michael, Holcombe, Chris, Coleman, Robert E, Jones, Louise, Ellis, Ian, Cuzick, Jack, Sainsbury, Richard, Garber, Judy, Warwick, Jane, Buchanan, Mary, Buser, Katharina, Cawthorn, Simon, Coleman, Robert, Dowsett, Mitch, Eastell, Richard, Ejlertsen, Bent, Forbes, John, Kahan, Zsuzsanna, Baclesse, François, Mansel, Robert, Palva, Tiina, Rydén, Lisa, Stuart, Mary, Vaz, Fatima, Marsiglia, Hugo, Benyoucef, Ahmed, Berton-Rigaud, Dominique, Loustalot, Catherine, Serin, Daniel, Kerbrat, Pierre, Eymard, Jean-Christophe, Giard-Lefevre, Sylvia, Bonichon-Lamichhane, Nathalie, Monnier, Alain, Tubiana-Mathieu, Nicole, Piot, Gilles, de Lara, Christine Tunon, Bernard, Olivier, Simon-Swirski, Hélène, Gladieff, Laurence, Regaud, I Claudius, Fouchet-Goudier, Marie-Joseph, Dohollou, Nadine, Aquitaine, Nord, Elgard-Maitre, Anne-Marie, Bergerat, Jean-Pierre, Petit, Thierry, Marti, Adina, Toussaint, Caroline, Del Piano, Francesco, Ibrahim, Mahmoud, Fric, Danièle, Hönig, Arnd, Müller, Volkmar, Marmé, Frederik, Rautenberg, Beate, Schmidt, Marcus, Hanusch, Claus, Paepke, Stefan, Kaltenecker, Gabriele, Lemster, Sabine, Tio, Joke, Reimer, Toralf, Schnappauf, Benjamin, Baumann, Klaus, Schrader, Iris, Mundhenke, Christoph, Liedtke, Cornelia, Meinerz, Wolfgang, Thomssen, Christoph, Christl, Klaus, Hitschold, Thomas, Goerke, Kay, Kast, Karin, Runnebaum, Ingo, Lindner, Christoph, Scheidel, Peter, Herwig, Uwe, Bangemann, Nikola, Sommer, Harald, Göhring, Kornelia, Tulusan, Augustinus, Stauß, Eva, Köhler, Günter, Zahm, Dirk, Augustin, Doris, Hocke, Andrea, Neunhöffer, Tanja, Schmatloch, Sabine, Heinrich, Georg, Groß, Sabine, Breitbach, G P, Scharl, Anton, Klare, Peter, Stefek, Andrea, Hoffmann, Gerald, Martignoni, Franca, Weiss, Erich, Emons, Günter, Tesch, Hans-Christian, Beckmann, Matthias, Schmutzler, Rita, Schütte, Martin, Aktas, Bahriye, Hille-Betz, Ursula, Deryal, Mustafa, Dan Costa, Serban, Blümel, Beate, Göhring, Uwe-Jochen, Kleine-Tebbe, Anke, Schumacher, Claudia, Jasmin, Pourfard, Christoph, Uleer, Kullmer, Uwe, Krabisch, Petra, Gätje, Regine, Schwenzer, Thomas, Hindenburg, Hans-Joachim, Rempen, Andreas, Höffkes, Heinz-Gert, Stickeler, Elmar, Reffert, Christian, Seitz, Stephan, Splitt, Gerd, Böhne, Petra, Gnauert, Karsten, Strittmatter, Hans-Joachim, Baake, Gerold, Rezai, Mahdi, Noesselt, Thomas, Köhne, C-H, Hanf, Volker, Strumberg, Dirk, Dall, Peter, Schleicher, Peter, Schleicher, Bernd, Beldermann, Frank, Berghorn, Michael, Baerens, Dirk-Thoralf, Kolberg, Hans-Christian, Bauer, Lelia, Brucker, Cosima, Steck, Thomas, Boyle, Frances, Chaudhuri, Anupam, Wagga, Wagga, Moylan, Eugene, Donovan, Jenny, Della-Fiorentina, Stephen, Abdi, Ehtesham, Marx, Gavin, Beadle, Geoffrey, Donovan, Michael, Bennett, Ian, Gill, Peter Grantley, Baker, Caroline, Masters, Richard, Blum, Robert, Collins, John, Law, Michael, Hart, Stewart, Kannourakis, George, Snyder, Raymond, Joseph, David, McCrystal, Michael, Campbell, Ian, Jakesz, Raimund, Selim, Ursula, Singer, Christian, Heck, Dietmar, Greil, Richard, Ramoni, Angela, Bjelic-Radisic, Vesna, Reichenauer, Arno, Horvath, Wilfried, Thaler, Josef, Fridrik, Michael, Keckstein, Joerg, Jan, Lamote, L'Hermitte, Marc, Roelstrate, Heidi, Dirix, Luc, Bambust, Inneke, Seret, Monique, Liebens, Fabienne, Maerevoet, Maria, D'Hondt, Lionel, Berliere, Martine, Nogaret, Jean-Marie, Simon, Phillipe, O'Hanlon, Deirdre, Redmond, Henry Paul, Hill, Arnold, Evoy, Denis, Kerin, Michael, Gupta, Rajnish, Martin, Michael J, Fritis, Marcela, Schwartz, Ricardo, Yañez, Maria Loreto, Peralta, Octavio, Graiff, Claudio, Artioli, Fabrizio, Generali, Daniele, Orzalesi, Lorenzo, Visini, Marilena, Michiara, Maria, Pavesi, Lorenzo, Ravaioli, Alberto, Porpiglia, Mauro, Puglisi, Fabio, Pinotti, Graziella, Brincat, Stephen, Buser, Katharina S, Rabaglio, Manuela, Rauch, Daniel, Chappuis, Pierre O, Zaman, Khalil, Bucher, Susanne, Bolliger, Barbara, Pagani, Olivia, Falck, Anna-Karin, Kaij, Jakob, Margolin, Sara, Muslumanoglum, Mahmut, Bertelli, Gianfilippo, Bramley, Maria, Bristol, James, Chandrasekharan, Sankaran, Crellin, Perric, Daoud, Raouf, Dodwell, David, Drew, Philip, Dubey, Sidharth, Evans, Abigail, Ferguson, Douglas, Gendy, Raafat, Hamed, Hisham, Harding-McKean, Claudia, Horgan, Kieran, Iqbal, Shabana, Jibril, Jibril A, Kokan, Jalal, Kneeshaw, Peter, Lansdown, Mark, Lennard, Tom, Linforth, Rick, McIntosh, Stuart, Mitra, Sankha, Neades, Glyn, Ooi, Jane Louise, Patel, Ashraf, Rayter, Zenon, Reichert, Robert, Roberts, Fiona, Roche, Nicola, Rogers, Colin, Royle, Gavin, Shah, Elizabeth, Sibbering, Mark, Skene, Anthony Iain, Smith, Simon, Sparrow, Geoffrey, Thompson, Alastair, Vaidya, Jayant, Wolstenholme, Virginia, Wood, Jeremy, Yiangou, Constantinos, Zammit, Charles, Thornton, Rochelle, Probert, Flonda, Fong, Akiko, Francis, Nicole, Gili, Manuela, Eigenberger, Rosita, Supply, Daisy, Lefever, Inge, Muller, Bettina, Zlatar, Zdenka, Feer, Petra, Gkantiragas, Ioannis, Virkki, Marjo, Everhard, Sibille, Lemonnier, Jerome, Garcia, Sara, Ghanem, Saliha, Cole, Anna, O'Hare, Debra, Cronin, Elaine, Roche, Trudi, Kennedy, Emer, Ballot, Jo, Killilea, Niamh, Jennings, Marian, Lowry, Laura, Maxwell, Moira, Burke, Margaret, Gonzaga, Aliana Guerrieri, Bollani, Giorgia, Bianchetti, Andrea, Scalvini, Anna, Cretella, Elisabetta, Pasqualini, Antonella, Gobbi, Angela, Roselli, Jenny, Lagati, Angelita, Rapacchi, Elena, Lanza, Annalisa, Pini, Emanuela, Picardo, Elisa, Maggiorotto, Furio, Sottile, Roberta, Vallini, Ilaria, Cilia, Nadia, Patel, Mital, Bamford, Linda, Robertshaw, Helen, Inman, Hayle, Hill, Naomi, Dexter, Jane, Peasgood, Emily, Batty, Imogen, Cocks, Shirley, Mistry, Raksha, Sidders, Mary, Foulstone, Emily, Garlicka, Helen, Dawe, Catherine, Elliott, Jackie, Rooke, Kathy, Morris, Christine, Lester, Yvonne, Gibson, Sian, Chittock, Jill, Skelton, Amy, Gallimore, Elizabeth, Downes, Charlotte, Billett, Lynn, Caddy, Simone, Cumming, Helen, Cowell-Smith, Sharon, Turner, Caroline, Fernando, Sunjalee, Goodwin, Sarah, Taylor, Jo-Anne, Baines, Kizzy, Downer, Susan, Pilcher, Alice, Dobson, Tracey, Osborne, Lynn, Kuenzig, Greg, Hancock, Denise, Melia, Deborah, Gullaksen, Elaine, Hartup, Susan, Henson, Amy, Gibb, Jane, Coombs, Sarah, Taylor, Caroline, Kirkby, Amy, Thomas, Issy, Makinson, Karen, Kano, Yukie, Shah, Zoheb, Hardstaff, Lisa, Townley, Barbara, Hill, Philippa, McCurrie, Marilyn, Grassby, Sue, Henderson, Pamela, Talbot, Elizabeth, Bell, Ashley, Kanani, Reshma, Johnson, Joanne, Jones, Richard, Foster, Mel, Troke, Becky, Congdon, Hilary, Pascoe, Julie, Whelan, Sian, Edwards, Jenna, Brinkworth, Elaine, Blizard, Sheila, Clarke, Alison, Stevens, Kim, Harvey, Carol, Stacey, Jill, Mitchell, Sadie, Lowry, Tracey, Buckley, Sarah, Collins, Clare, Green, Liz, Jones, Helen, Conteh, Veronica, Ducket, Tracey, Kotze, Michelle, Strider, Paula, Stouraitis, Marina, Sundberg, Jan, Babiker, Abdel, Collins, Rory, Klijn, Jan, Ralston, Stuart, Tattersall, Martin, Weller, Ian, De Sousa, Andreia, Edwards, Rob, Ferguson, Sheila, Hickman, Jane, Johnson, Damian, Haidar, Nadia, Hammond, Victoria, Heighway, Emma, Ndoutoumou, Amalia, Sahota, Navdip, White, Laura, Aigret, Benoit, Batra, Priyanka, Knox, Jill, Oke, Adedayo, Ostler, Richard, and Sasieni, Peter

Subjects
Medicine (all), Medizin, skin and connective tissue diseases
Abstract

Third-generation aromatase inhibitors are more effective than tamoxifen for preventing recurrence in postmenopausal women with hormone-receptor-positive invasive breast cancer. However, it is not known whether anastrozole is more effective than tamoxifen for women with hormone-receptor-positive ductal carcinoma in situ (DCIS). Here, we compare the efficacy of anastrozole with that of tamoxifen in postmenopausal women with hormone-receptor-positive DCIS.In a double-blind, multicentre, randomised placebo-controlled trial, we recruited women who had been diagnosed with locally excised, hormone-receptor-positive DCIS. Eligible women were randomly assigned in a 1:1 ratio by central computer allocation to receive 1 mg oral anastrozole or 20 mg oral tamoxifen every day for 5 years. Randomisation was stratified by major centre or hub and was done in blocks (six, eight, or ten). All trial personnel, participants, and clinicians were masked to treatment allocation and only the trial statistician had access to treatment allocation. The primary endpoint was all recurrence, including recurrent DCIS and new contralateral tumours. All analyses were done on a modified intention-to-treat basis (in all women who were randomised and did not revoke consent for their data to be included) and proportional hazard models were used to compute hazard ratios and corresponding confidence intervals. This trial is registered at the ISRCTN registry, number ISRCTN37546358.Between March 3, 2003, and Feb 8, 2012, we enrolled 2980 postmenopausal women from 236 centres in 14 countries and randomly assigned them to receive anastrozole (1449 analysed) or tamoxifen (1489 analysed). Median follow-up was 7·2 years (IQR 5·6-8·9), and 144 breast cancer recurrences were recorded. We noted no statistically significant difference in overall recurrence (67 recurrences for anastrozole vs 77 for tamoxifen; HR 0·89 [95% CI 0·64-1·23]). The non-inferiority of anastrozole was established (upper 95% CI

Published
2016

30. Proteomic identification of predictive biomarkers of neo-adjuvant chemotherapy resistance in breast cancer: A possible role of AkT-1, FAKY397, 14-3-3 theta/tau, tBID and BcL-XL?

Author

Hussain, Tasadooq, primary, Scaife, Lucy, additional, Hodgkinson, Victoria, additional, Agarwal, Vijay, additional, Kneeshaw, Peter, additional, McManus, Penelope, additional, Mahapatra, Tapan, additional, Drew, Phil, additional, Lind, Mike, additional, and Cawkwell, Lynn, additional

Published
2013
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39. Clinical response to primary Letrozole therapy in women over 70 years with early breast cancer: A retrospective study with a 5 year follow up

Author

Hussain, Tasadooq, primary, Agarwal, Vijay, additional, Garimella, Veerabhadram, additional, Rhadhakrishna, Selvi, additional, Fox, John, additional, Kneeshaw, Peter J., additional, Long, Ervine, additional, Mahapatra, Tapan, additional, McManus, Penelope, additional, Lind, Michael J., additional, Drew, Philip, additional, and Cawkwell, Lynn, additional

Published
2012
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