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Your search keyword '"Ko, Sung Jun"' showing total 16 results
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16 results on '"Ko, Sung Jun"'

7. Protective Effectiveness of Inactivated Hantavirus Vaccine Against Hemorrhagic Fever With Renal Syndrome.

Author

Jaehun Jung, Sung-Jun Ko, Hong Sang Oh, Song Mi Moon, Jin-Won Song, Kyungmin Huh, Jung, Jaehun, Ko, Sung-Jun, Oh, Hong Sang, Moon, Song Mi, Song, Jin-Won, and Huh, Kyungmin

Subjects
HANTAVIRUS diseases, HEMORRHAGIC fever, DISEASE incidence, VACCINE effectiveness, ARENAVIRUS diseases, VACCINATION
Abstract

As there is no effective treatment against hemorrhagic fever with renal syndrome (HFRS), the development of effective vaccine is important. An inactivated hantavirus vaccine (IHV) has been used in Korea, but there has been controversy regarding its effectiveness. We conducted a case-control study to evaluate the vaccine effectiveness (VE) of IHV against HFRS in the Korean military. Unadjusted and adjusted VEs of IHV were 59.1% and 58.9%, respectively. VE was higher in divisions with high incidence of HFRS (unadjusted VE, 71.4%; adjusted VE, 78.7%). Our study demonstrated the moderate effectiveness of IHV in high-risk populations residing in endemic area. [ABSTRACT FROM AUTHOR]

Published
2018
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12. Epidermal growth factor receptor mutations and anaplastic lymphoma kinase rearrangements in lung cancer with nodular ground-glass opacity

Author

Ko, Sung-Jun, primary, Lee, Yeon Joo, additional, Park, Jong Sun, additional, Cho, Young-Jae, additional, Yoon, Ho Il, additional, Chung, Jin-Haeng, additional, Kim, Tae Jung, additional, Lee, Kyung Won, additional, Kim, Kwhanmien, additional, Jheon, Sanghoon, additional, Kim, Hyojin, additional, Lee, Jae Ho, additional, and Lee, Choon-Taek, additional

Published
2014
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16. Performance of the BD MAX MDR-TB assay in a clinical setting and its impact on the clinical course of patients with pulmonary tuberculosis: a retrospective before-after study.

Author

Ko SJ, Yoon KH, and Lee SH

Abstract

Background: Missing isoniazid (INH) resistance during tuberculosis (TB) diagnosis can worsen the outcomes of INH-resistant TB. The BD MAX MDR-TB assay (BD MAX) facilitates the rapid detection of TB and INH and rifampin (RIF) resistance; however, data related to its performance in clinical setting remain limited. Moreover, its effect on treatment outcomes has not yet been studied., Methods: We compared the performance of BD MAX for the detection of INH/RIF resistances to that of the line probe assay (LPA) in patients with pulmonary TB (PTB), using the results of a phenotypic drug sensitivity test as a reference standard. The treatment outcomes of patients who used BD MAX were compared with those of patients who did not., Results: Of the 83 patients included in the study, the BD MAX was used for an initial PTB diagnosis in 39 patients. The sensitivity of BD MAX for detecting PTB was 79.5%. The sensitivity and specificity of BD MAX for INH resistance were both 100%, whereas these were 50.0% and 95.8%, respectively, for RIF resistance. The sensitivity and specificity of BD MAX were comparable to those of LPA. The BD MAX group had a shorter time interval from specimen request to the initiation of anti-TB drugs (2.0 days vs. 5.5 days, p=0.001)., Conclusion: BD MAX showed comparable performance to conventional tests for detecting PTB and INH/RIF resistances. The implementation of BD MAX as a diagnostic tool for PTB resulted in a shorter turnaround time for the initiation of PTB treatment.

Published
2024
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