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4 results on '"Koekkelkoren, A. M. H. C."'

1. Ancient herpes simplex 1 genomes reveal recent viral structure in Eurasia

Author

Guellil, Meriam, primary, van Dorp, Lucy, additional, Inskip, Sarah A., additional, Dittmar, Jenna M., additional, Saag, Lehti, additional, Tambets, Kristiina, additional, Hui, Ruoyun, additional, Rose, Alice, additional, D’Atanasio, Eugenia, additional, Kriiska, Aivar, additional, Varul, Liivi, additional, Koekkelkoren, A. M. H. C., additional, Goldina, Rimma D., additional, Cessford, Craig, additional, Solnik, Anu, additional, Metspalu, Mait, additional, Krause, Johannes, additional, Herbig, Alexander, additional, Robb, John E., additional, Houldcroft, Charlotte J., additional, and Scheib, Christiana L., additional

Published
2022
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3. IDDS Archeologie rapport 2014

Author

Koekkelkoren, A. M. H. C., Meijer, Y., Griffioen, A.A.J., Hendriksen, M., Brandenburgh, C., and IDDS archeologie

Subjects
Archaeology, bebouwing aanwezig was vanaf de 15e eeuw tot en met de 21e eeuw, waarbij sprake was van vijf verschillende bewoningsfasen, Temporal coverage: Late Middeleeuwen - Nieuwe Tijd
Published
2019
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4. Ancient herpes simplex 1 genomes reveal recent viral structure in Eurasia

Author

Scheib, Christiana, Houldcroft, Charlotte, Robb, John, Cessford, Craig, Dittmar, Jenna, Inskip, Sarah, Rose, Alice, Hui, Rouyun, Scheib, Christiana [0000-0003-4158-8296], Houldcroft, Charlotte [0000-0002-1833-5285], Cessford, Craig [0000-0001-7291-7828], Apollo - University of Cambridge Repository, Guellil, Meriam [0000-0002-7235-4604], van Dorp, Lucy [0000-0002-6211-2310], Inskip, Sarah A [0000-0001-7424-2094], Dittmar, Jenna M [0000-0003-3514-1869], Saag, Lehti [0000-0002-2274-8138], Tambets, Kristiina [0000-0002-8173-6380], Hui, Ruoyun [0000-0002-5689-7131], Rose, Alice [0000-0003-1755-7174], D'Atanasio, Eugenia [0000-0002-4965-246X], Kriiska, Aivar [0000-0002-0900-7626], Varul, Liivi [0000-0002-8498-3352], Koekkelkoren, A M H C [0000-0003-0721-1727], Goldina, Rimma D [0000-0002-8689-0512], Metspalu, Mait [0000-0003-3099-9161], Krause, Johannes [0000-0001-9144-3920], Herbig, Alexander [0000-0003-1176-1166], Houldcroft, Charlotte J [0000-0002-1833-5285], and Scheib, Christiana L [0000-0003-4158-8296]

Subjects
2 Aetiology, Infectious Diseases, 4301 Archaeology, Sexually Transmitted Infections, 2.2 Factors relating to the physical environment, FOS: Health sciences, Infection, 4303 Historical Studies, 4401 Anthropology, 3105 Genetics, 43 History, Heritage and Archaeology, 31 Biological Sciences, 44 Human Society
Abstract

Funder: Wellcome Trust, Human herpes simplex virus 1 (HSV-1), a lifelong infection spread by oral contact, infects a majority of adults globally. Phylogeographic clustering of sampled diversity into European, pan-Eurasian, and African groups has suggested the virus codiverged with human migrations out of Africa, although a much younger origin has also been proposed. We present three full ancient European HSV-1 genomes and one partial genome, dating to the 3rd-17th century CE, sequenced to up to 9.5× with paired human genomes up to 10.16×. Considering a dataset of modern and ancient genomes we apply phylogenetic methods to estimate the age of sampled modern Eurasian HSV-1 diversity to 4.68 (3.87 - 5.65) kya. Extrapolation of estimated rates to a global dataset points to the age of extant sampled HSV-1 as 5.29 (4.60-6.12) kya, suggesting HSV-1 lineage replacement coinciding with the late Neolithic period and following Bronze Age migrations.

Published
2022
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