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Simple methods for quantitative evaluations of individual motor performance are crucial for the early detection of motor deterioration. Sit-to-stand movement from a chair is a mechanically demanding component of activities of daily living. Here, we developed a novel method using the ground reaction force and center of pressure measured from the Nintendo Wii Balance Board to quantify sit-to-stand movement (sit-to-stand score) and investigated the age-related change in the sit-to-stand score as a method to evaluate reduction in motor performance. The study enrolled 503 participants (mean age ± standard deviation, 51.0 ± 19.7 years; range, 20–88 years; male/female ratio, 226/277) without any known musculoskeletal conditions that limit sit-to-stand movement, which were divided into seven 10-year age groups. The participants were instructed to stand up as quickly as possible, and the sit-to-stand score was calculated as the combination of the speed and balance indices, which have a tradeoff relationship. We also performed the timed up and go test, a well-known clinical test used to evaluate an individual’s mobility. There were significant differences in the sit-to-stand score and timed up and go time among age groups. The mean sit-to-stand score for 60s, 70s, and 80s were 77%, 68%, and 53% of that for the 20s, respectively. The timed up and go test confirmed the age-related decrease in mobility of the participants. In addition, the sit-to-stand score measured using the Wii Balance Board was compared with that from a laboratory-graded force plate using the Bland–Altman plot (bias = −3.1 [ms]-1, 95% limit of agreement: −11.0 to 3.9 [ms]-1). The sit-to-stand score has good inter-device reliability (intraclass correlation coefficient = 0.87). Furthermore, the test–retest reliability is substantial (intraclass correlation coefficient = 0.64). Thus, the proposed STS score will be useful to detect the early deterioration of motor performance.

Item does not contain fulltext Stress shielding-related bone loss occurs after total hip arthroplasty because the stiffness of metallic implants differs from that of the host femur. Although reducing stem stiffness can ameliorate the bone resorption, it increases stress at the bone-implant interface and can inhibit fixation. To overcome this complication, a novel cementless stem with a gradient in Young's modulus was developed using Ti-33.6Nb-4Sn (TNS) alloy. Local heat treatment applied at the neck region for increasing its strength resulted in a gradual decrease in Young's modulus from the proximal to the distal end, from 82.1 to 51.0GPa as calculated by a heat transfer simulation. The Young's modulus gradient did not induce the excessive interface stress which may cause the surface debonding. The main purpose of this study was to evaluate bone remodeling with the TNS stem using a strain-adaptive bone remodeling simulation based on finite element analysis. Our predictions showed that, for the TNS stem, bone reduction in the calcar region (Gruen zone 7) would be 13.6% at 2years, 29.0% at 5years, and 45.8% at 10years postoperatively. At 10 years, the bone mineral density for the TNS stem would be 42.6% higher than that for the similar Ti-6Al-4V alloy stem. The stress-strength ratio would be lower for the TNS stem than for the Ti-6Al-4V stem. These results suggest that although proximal bone loss cannot be eliminated completely, the TNS stem with a Young's modulus gradient may have bone-preserving effects and sufficient stem strength, without the excessive interface stress. 9 p.

Objective Eating is important in rehabilitation and is evaluated using joint angles that serve as kinematic information. Joint angles of the upper extremities during eating have been reported for men and for women; however, no study has investigated these joint angles in terms of gender differences. At present, no information is available on gender differences as individual factors of upper extremity joint angles during eating. Therefore, the present study investigated gender differences in upper limb joint angles during eating tasks involving a spoon or chopsticks. Methods We examined eating motions in 12 healthy Japanese men and 13 healthy Japanese women (aged 20-39 years) and compared the two groups. Motions were assessed using inertial sensors and three-dimensional motion analysis. Results We established, separately for men and women, the maximum angle and the range of motion (RoM) for each upper limb joint. Women generally had greater RoMs for all upper limb joints than men did. When subjects used a spoon, statistically significant differences and large effect sizes were observed for the maximum elbow joint flexion angle and the RoMs of the shoulder joint in abduction, flexion, and internal rotation. When subjects used chopsticks, statistically significant differences and large effect sizes were observed for maximum angles of shoulder joint internal rotation, elbow joint flexion, and wrist joint radial flexion and for the RoM of shoulder joint abduction. Conclusions We concluded that there are significant gender differences in upper limb joint angles during eating, and that these differences are influenced by numerous factors.

Introduction/Background The Japanese Orthopaedic Association proposed the term “locomotive syndrome” (LS) to define people at risk of requiring nursing care because of problems with their locomotive system. There is a need to develop simple methods to quantify motor performance and the early detection of LS. Sit-to-stand (STS) movements are a mechanically demanding task in everyday activities and represent motor performance. In the present study, we have developed a novel method to quantify STS movements (STS score) using ground reaction force and center of pressure data from the Nintendo Wii Balance Board (WBB). We investigated whether the STS score can predict LS. Material and method The study enrolled 155 subjects aged over 65 years. Individuals were divided into three groups based on LS risk tests results. The subjects were instructed to stand up as quickly as possible on the WBB, and the STS score was calculated as the combination of the speed and balance indices. We also performed a timed up and go test and hand-grip strength test to evaluate the motor status. Results There were significant differences in each test among the groups ( Table 1 ). Conclusion The STS score significantly decreased with the severity of LS and thus could be used to assess LS in elder people.

We surveyed the score of Japanese version Craig Handicap Assessment and Reporting Technique (CHART) in addition to the original questionnaire in 90 patients with spinal cord injury who belonged to Spinal Injuries Japan prefectural branch office in Miyazaki. We received 64 answers for the questionnaire. To clarify the relation between CHART and welfare apparatus, we added our original questionnaire for locomotion, elimination and decubitus ulcers, and compared the score of each CHART area in this study.The results showed that the area of independence of body was highest, and the area of occupation was lowest in the score of CHART. In addition, the elimination-control-independent group was significantly higher than the non-elimination-independent group for the total CHART score.On the other side, most patients used hand-operated wheelchairs indoors and outdoors. The CHART score of the normal type wheelchair group was higher than that of modified wheelchair group. In the comparison of the presence and absence of decubitus ulcer in past medical history, the total CHART score in the present group was lower than the absence group, but not significantly.

The purpose of this study was to analyze the effect of lumbar spine fusion on the superior adjacent intervertebral disk in the context of disk degeneration, using a nonlinear three-dimensional finite element method. Detailed L3-L5 motion segment models of normal and degenerated intervertebral disks were developed. In fusion models, L4-L5 was fixed by either posterolateral fusion or posterior lumbar interbody fusion (PLIF). Various loading conditions such as compression loading, compression loading plus flexion moment loading, or compression loading plus extension moment loading were applied to study the corresponding stress. Tresca stress on the posterolateral part of intervertebral annulus fiber and von Mises stress on the vertebral endplate (the superior and inferior sides of L3 and L4) were reduced in all degenerated disk models compared with the normal disk models. The PLIF model showed an increase in the percentage change of stress on the vertebral endplate and on the intervertebral annulus fibrosus when flexion and extension moment loadings were applied. This finding suggests that surgeons should consider the risk of exacerbating degeneration of intervertebral disks by undertaking lumbar spine fusion, when degeneration is found in intervertebral disks adjacent to vertebrae requiring fusion.

Biomechanical analyses under compression only, and for a combination of flexion, extension, rotation, and lateral bending were performed to evaluate the stress of the interarticular portion of the lumbar vertebra using a nonlinear three-dimensional finite element method. A detailed three-dimensional L4-L5 motion segment model was developed that took into consideration the material nonlinearities of ligaments and annular fibers and the contact nonlinearities of facet joints. For a more accurate examination, the separation of cortical bone and cancellous bone for both posterior and anterior elements were also considered. The stress in the pars interarticularis was weakest under compression alone, but stronger under compression with lateral bending loading, with flexion, with rotation, and with extension. Under each loading condition, the region of the stress concentration was consistent with the separated region of the spondylolysis observed in clinical situations. Since the stress in the pars interarticularis was high under extension and rotation in particular, those loadings were suggested to be relatively high risk factors leading to spondylolysis.

We evaluated stresses in the anterior middle third of the tibia that have been reported to predict a poor prognosis for tibial stress fractures compared to other predominant sites (posteromedial regions of the distal third and proximal third). The effect of two different loads (bending-compression load and torsional load) on three sites was investigated using a three-dimensional finite element method. The model was constructed using the tibia, fibula, proximal tibiofibular joint, interosseous membrane, and tibiofibular ligament based on computed tomography scans obtained at 4-mm intervals of the lower leg of a 20-year-old woman who exhibited no abnormal findings on roentgenograms. First, a normal model was constructed using normal material properties, and then the model was modified to produce fracture models by varying the mechanical properties of each predominant site and expanding the area in three gradual phases on the assumption that the fracture advanced in three phases. Each model was tested against the same two loads, and stresses at the nodal points on the border of the fracture area and normal area were compared in each cross section to determine the effect of the load on fracture advancement. In response to torsional load, both the normal model and fracture models tended to show higher values for the posteromedial distal third than the anterior middle third. By examining the bending-compression load it could be seen that the mean peak value significantly decreased between the first and second phases in fracture models of the anterior middle third. This finding was inconsistent with our previous belief that the bending-compression load would have more serious consequences than the torsional load. In contrast, when the area of fracture was expanded into the third phase, maximum values were significantly higher than during the second phase. No similar finding was observed for the posteromedial distal third, suggesting that the anterior middle third may have the same stable biomechanical conditions as the posteromedial distal third at an earlier stage and thus have little influence on fractures. When the fracture is more advanced, however, the conditions change suddenly, and a bending-compression load may adversely affect the mechanical conditions in this area and thereby cause complete fracture.

The risk of accelerating the degeneration of adjacent disc levels after lumbar spinal fusion is a controversial issue. A finite element model consisting of L1 to L5 lumbar spines was used to assess the effect on adjacent disc level after lumbar spinal fusion. We compared intact, L4/5 posterior interbody fusion (PLF), and L4/5 posterior lumbar interbody fusion (PLIF) models. The loading conditions applied were compressive force, compressive force plus flexion moment, and compressive force plus extension moment. Evaluations were made for von Mises stress on each vertebral end-plate, Tresca stress of all the annulus fibrosus, and Tresca stress of the annulus fibrosus from the posterior surface of the disc to the neural foramen. As the result, the von Mises stress adjacent to the fusion level was higher than the other nonfusion levels; it was higher under conditions of flexion moment loading plus compression loading [112% (2.59 PMa) in the PLF model and 117% (2.72 Mpa) in the PLIF model] than in the intact model. The Tresca stress of all the annulus fibrosus adjacent to the fusion level was higher than that on other nonfusion intervertebral levels; it was higher under conditions of flexion moment loading plus compression loading [127% (0.57 PMa) in the PLF model and 209% (0.89 Mpa) in the PLIF model] than in the intact model. The Tresca stress of the annulus fibrosus from the posterior surface of the disc to the neural foramen adjacent to the fusion level was higher than that on other nonfusion intervertebral levels; and it was higher under conditions of flexion moment loading plus compression loading [107% (1.48 PMa) in the PLF model and 112% (1.54 Mpa) in the PLIF model] than in the intact model. These findings demonstrate that with lumbar fusion, stresses on the vertebral end-plate and the annulus fibrosus were high adjacent to the fusion level; furthermore, stresses were higher in the PLIF model than in the PLF model. These results suggested that lumbar spinal fusion might bring with it a risk of damage to the annulus fibrosus and the vertebral end-plate adjacent to the fusion level.

This study evaluated the influence of head mass on the acceleration of the head and neck complex in automobile rear-end collisions using a three-dimensional finite element method. The geometry of the finite element model is based on a cervical (C2–7) motion segment of a 20-year-old man that was obtained by computed tomography. Four types of models were prepared by changing the parameters of mass for an examination of the effects of head mass. Simulated loads were applied at the lower end of the C7 vertebra, with the axial direction constrained. Each model was loaded, and the head acceleration and distribution of von Mises stress were analyzed. Stress was observed to concentrate on the C2/3, C5/6 and C6/7 intervertebral discs. With a large head mass, the delay of the initial rise of the acceleration curve was large and the value of acceleration was small. On the contrary, when the head mass was small, the acceleration curve started to rise earlier. The acceleration curve of the model with the head mass of 1.0 kg was the closest to that of the experiments by Severy. Head mass is an important factor which influences the dynamic response of the head in rear-end collisions.

Study design A new cage made from a forged composite of unsintered hydroxyapatite particles and poly-L-lactide (F-u-HA/PLLA) is compared biomechanically with the Ray threaded fusion cage. Objectives To compare the stability imparted to the human cadaveric spine by two different threaded cervical cages and the effect of cyclic loading on construct stability. Summary of background data Threaded cages have been developed for use in anterior cervical interbody fusions to provide initial stability during the fusion process. However, metallic instrumentation has several limitations. Recently, totally bioresorbable bone fixation devices made of F-u-HA/PLLA have been developed, including a cage for spinal interbody fusion. However, no biomechanical study has compared the F-u-HA/poly-L-lactide (PLLA) cage with metallic cages. Methods For this study, 12 fresh ligamentous human cervical spines (C4-C7) were used. After anterior discectomy across C5-C6, stabilization was achieved with the F-u-HA/PLLA cage in six spines and with the Ray threaded fusion cage in the remaining six spines. Biomechanical testing of the spines was performed with six degrees of freedom before and after stabilization, and after cyclic loading of the stabilized spines (5000 cycles of flexion-extension at 0.5 Nm). Results The specimens stabilized with either the F-u-HA/PLLA cage or the Ray cage were significantly more stable than the discectomy case in all directions except in extension. In extension, both groups were stiffer, although not at a significant level (P > 0.05). After fatigue, the stiffness, as compared with that in the prefatigue case, decreased in both groups, although not at a significant level. The Ray cage group exhibited better stability than the F-u-HA/PLLA cage group in all directions, although a significant difference was found only in right axial rotation. Conclusions The F-u-HA/PLLA cage has the possibility to supplant the use of metallic devices in interbody fusions of the cervical spine.

The cervical spinal cord is at a great risk for injury during traumatic accidents occurring within people of relatively young age. Spinal cord injury can not be easily characterized clinically nor through in vitro testing. An understanding of cervical spinal cord deformation is important for defining an injury threshold of the spinal cord. Therefore, an analytical method may be beneficial for determining the response of the spinal cord response to external loads on the spine. We have developed a three-dimensional, non-linear finite element model to quantify physiologic strains and stresses in the cervical spinal cord placed in the ligamentous C5-C6 motion segment. Compressive loads along with flexion and extension moments were applied to the bony segment and not the cord itself. Motion data, shown in degrees of movement in flexion and extension calculated for the model showed a close representation to in vivo data. Von Mises stress plots and strains on the cervical spinal cord were computed. This model represents a first attempt by the authors to analytically quantify the mechanical response of the spinal cord to cervical spine injury.

Autologous bone grafts for posterolateral lumbar fusion are harvested from the iliac crests. Recently, several alternatives to autologous bone have been evaluated (such as graft substitutes, graft extenders, or both) with variable results. However, no clinical long-term studies have validated the efficacy of these techniques in posterolateral lumbar fusion. This study evaluated radiographic and histologic findings in four patients (mean age, 66 years) during the first 5 years after posterolateral fusion with an hydroxyapatite block. The mean followup was 7 years 1 month. Radiologic evaluation was by plain radiographs and computed tomography scans. Histologic evaluation was done in one patient. Capillaries extended into the porous structure of the hydroxyapatite substrate, and some of the pores were replaced by newly formed bone tissue. The long-term results of graft substitutes were stable and hydroxyapatite appeared to have some potential to achieve union in posterolateral lumbar fusion. However, hydroxyapatite block alone has not functioned effectively as a complete graft substitute in posterolateral lumbar fusion. Thus, a suitable osteogenic material is required to induce the formation of new bone and achieve a solid union.

Shortened cementless femoral stems have become popular with the advent of minimally invasive total hip arthroplasty (THA). Successful THA requires initial stem stability and prevention of stress shielding-mediated bone loss, although the effect of stem shortening is controversial. Here we experimentally examined whether stem shortening affects stress shielding and initial stability. Anatomical stems (length, 120 mm) were cut to an 80 mm or 50 mm length. Ten tri-axial strain gauges measured the cortical strain on each stem-implanted femur to evaluate stress shielding. Two transducers measured axial relative displacement and rotation under single-leg stance loading. The 50 mm stem increased the equivalent strains with respect to the original stem in the proximal calcar region (31.0% relative to intact strain), proximal medial region (63.1%), and proximal lateral region (53.9%). In contrast, axial displacement and rotation increased with a decreasing stem length. However, the axial displacement of the 50 mm stem was below a critical value of 150 µm for bone ingrowth. Our findings indicate that, with regard to a reduction in stem length, there is a tradeoff between stress shielding and initial stability. Shortening the stem up to 50 mm can promote proximal load transfer, but bone loss would be inevitable, even with sufficient initial stability for long-term fixation.

Stress shielding-related proximal femoral bone loss after total hip arthroplasty occurs because of the different stiffness of metallic alloy stems and host bone. To overcome this, we fabricated a low-modulus cementless hip stem from β-type Ti-33.6Nb-4Sn alloy (TNS). Then we evaluated its stiffness, stress shielding, and initial stability compared with a similar Ti-6Al-4V alloy stem. Stiffness was determined by axial compression and cantilever-bending tests. Thirteen triaxial strain gages measured cortical strain. Stress shielding was defined as the percentage of intact strain after stem insertion. To evaluate initial stability, displacement transducers measured axial relative displacement and rotation. Intact and implanted femurs underwent single-leg-stance loading. Axial stiffness was 56% lower in the TNS stem than in the Ti-6Al-4V stem, and bending stiffness of the TNS stem decreased gradually from the proximal region to the distal region, being ≤ 53% that of the Ti-6Al-4V stem, indicating gradation of Young's modulus. The TNS stem decreased stress shielding in the proximal calcar region (A1: 83%, B1: 85% relative to intact cortical strain) without affecting the proximal lateral region (B3: 53%). The initial stabilities of the stems were comparable. These findings indicate that the TNS stem with gradation of Young's modulus minimizes proximal femoral bone loss and biological fixation, improving long-term stability.

Object. The goal of this study was to evaluate the comparative efficacy of three commonly used anterior thoracolumbar implants: the anterior thoracolumbar locking plate (ATLP), the smooth-rod Kaneda (SRK), and the Z-plate. Methods. In vitro testing was performed using the T9—L3 segments of human cadaver spines. An L-1 corpectomy was performed, and stabilization was achieved using one of three anterior devices: the ATLP in nine spines, the SRK in 10, and the Z-plate in 10. Specimens were load tested with 1.5-, 3-, 4.5-, and 6-Nm in flexion and extension, right and left lateral bending, and right and left axial rotation. Angular motion was monitored using two video cameras that tracked light-emitting diodes attached to the vertebral bodies. Testing was performed in the intact state in spines stabilized with one of the three aforementioned devices after the devices had been fatigued to 5000 cycles at ± 3 Nm and after bilateral facetectomy. There was no difference in the stability of the intact spines with use of the three devices. There were no differences between the SRK- and Z-plate—instrumented spines in any state. In extension testing, the mean angular rotation (± standard deviation) of spines instrumented with the SRK (4.7 ± 3.2°) and Z-plate devices (3.3 ± 2.3°) was more rigid than that observed in the ATLP-stabilized spines (9 ± 4.8°). In flexion testing after induction of fatigue, however, only the SRK (4.2 ± 3.2°) was stiffer than the ATLP (8.9 ± 4.9°). Also, in extension postfatigue, only the SRK (2.4 ± 3.4°) provided more rigid fixation than the ATLP (6.4 ± 2.9°). All three devices were equally unstable after bilateral facetectomy. The SRK and Z-plate anterior thoracolumbar implants were both more rigid than the ATLP, and of the former two the SRK was stiffer. Conclusions. The authors' results suggest that in cases in which profile and ease of application are not of paramount importance, the SRK has an advantage over the other two tested implants in achieving rigid fixation immediately postoperatively.

Biomechanical analyses under compressive load, flexion, and extension torque were performed, using a nonlinear three-dimensional finite element method, to evaluate stability in posterolateral fusion. Effects of facet fusion and disc denucleation on posterolateral fusion were also examined. Using an initially prepared L4-5 motion segment model, we prepared a denucleation model, posterolateral fusion models classified by presence or absence of denucleation and facet fusion, and an interbody fusion model. In the denucleation model, rigidity was less than in the normal model, and maximum rigidity was analyzed for the interbody fusion model. The effect of denucleation on posterolateral fusion was also analyzed. Taking into account the instability of the anterior elements, including the intervertebral disc, appears to be clinically important. In the posterolateral fusion model under compressive load, the axis of rotation moved principally toward the fusion mass, and axial displacement and flexion rotation were induced. Sagittal rotation angles under flexion and extension torque were 1.5 degrees -2.3 degrees at a maximum moment of 15 N-m, demonstrating elasticity of posterolateral fusion. When combined with facet fusion, posterolateral fusion yielded increase of load transfer across the lamina and decrease of rotation angle of about 10% under flexion-extension torque. Adjunctive clinical use of facet fusion should permit more solid posterolateral fusion.

This paper discusses the biomechanics and long-term results of posterolateral (PL) lumber fusion for degenerative lumbar spinal diseases. In the biomechanical study, the geometry of the finite element model is based on the L4-5 motion segment. The disc degeneration model was simulated by changing the interbody material properties. The behavior of the PL fusion model and the effects of the anterior elements on PL lumber fusion were studied in compression, flexion, and extension. In the clinical study, 40 patients with a mean age of 39 years (19 to 63) were treated with PL fusion and the mean follow-up period was 14 years. Clinical evaluation was made by the Japanese Orthopaedic Association (J.O.A.) score. Fusion success was determined by X-ray radiographs. Stress distribution results indicate that there were high stresses in the upper part of the grafted bone for PL fusion. The axial displacement of the L4 vertebral body and the stress of the grafted bone for PL fusion increased in the disc degeneration model. In flexion, the extension load stress concentrated on the L4 side of PL fusion model between transverse processes. Clinically, the J.O.A. score improved by 24 points postoperatively. Radiographically, the success rate of the fusion was 93%. The long-term results were so good that this technique can be recommended. It is suggested that the instability including the degree of disc degeneration is one of the important factors in PL lumbar fusion.

Periprosthetic bone remodeling is commonly seen after total hip arthroplasty, but the remodeling pattern differs among patients even in those implanted with the same stem. Remodeling occurs mainly because of the difference in load transmitted from the stem to the femur. In this study, we evaluated the load-transfer pattern in eight female patients implanted with an anatomical stem on an individual basis by patient-specific finite element analysis that is based on pre- and postoperative computed tomography images. Load transfer was evaluated using interface stress between the stem and bone. One of eight patients demonstrated proximal dominant load transfer, while the other patients demonstrated a distal dominant pattern. The results of our biomechanical simulations reveal the differences in load-transfer pattern after surgery among patients with the same anatomical stem.

The objective of this study was to biomechanically determine the effect of the severity of acetabular dysplasia, number and positions of screws and type of bone graft material used on the initial fixation strength of the acetabular reinforcement ring with hook (Ganz ring) using the finite element method. Relative micromotion increased as the severity of acetabular dysplasia increased and tended to decrease as the number of screws increased, but varied according to screw placement position. Increased strength of the bone graft material led to decreased relative micromotion. Biomechanically, the Ganz ring can be placed securely using 3 screws in patients with Crowe 1 dysplasia. However, in patients with Crowe 2 or higher dysplasia, it is necessary to spread at least 4 screws across an area of good host bone.

Since 1984, cervical spinal canal enlargement has been performed in 33 patients with cervical myelopathy (21 with cervical ossification of the posterior longitudinal ligament and 12 with cervical spondylosis). In expansive open-door laminoplasty, the average age at surgery was 57.5 years and the average follow-up period was 4 years and 5 months. In double door laminoplasty, the average age at surgery was 65.3 years and the average follow-up period was 1 year and 2 months. Clinical results were evaluated using JOA score for cervical myelopathy and recovery rates using Hirabayashi's method. In expansive open-door laminoplasty the preoperative average score was 8.7 points, and this improved to 12.2 points postoperatively. The average recovery rate was 42.2%, In double door laminoplasty the average preoperarve score was 8.1 increasing to 11.6 postoperatively The average recovery rate was 39.3%. Radiologically, cervical alignment showed a tendency to be straight, and postoperative cervical antero-posterior movement decreased. Cervical laminoplasty is a useful procedure for treatment of cervical myelopathy.

Finite element analysis (FEA) has been applied for the biomechanical analysis of acetabular dysplasia, but not for biomechanical studies of periacetabular osteotomy (PAO) or those performing analysis taking into consideration the severity of acetabular dysplasia. This study aimed to perform biomechanical evaluation of changes in stress distribution following PAO and to determine the effect of the severity of developmental dysplasia of the hip (DDH) using three-dimensional FEA.A normal model was designed with a 25° center-edge (CE) angle and a 25° vertical-center-anterior margin (VCA) angle. DDH models were designed with CE and VCA angles each of 10, 0, or -10°. Post-PAO models were created by separating each DDH model and rotating the acetabular bone fragment in the anterolateral direction so that the femoral head was covered by the acetabular bone fragment, with CE and VCA angles each at 25°.Compared to the normal hip joint model, the DDH models showed stress concentration in the acetabular edge and contacting femoral head, and higher stress values; stress increased with decreasing CE and VCA angles. Compared to the DDH models, the post-PAO models showed near-normal patterns of stress distribution in the acetabulum and femoral head, with stress concentration areas shifted from the lateral to medial sides. Stress dispersion was especially apparent in the severe acetabular dysplasia models. PAO provided greater decreases in the maximum values of von Mises stress in the load-bearing area of the acetabulum and femoral head when applied to the DDH models of higher degrees of severity, although the values increased with increasing severity of DDH.PAO is expected to provide biomechanical improvement of the hip joint and to be particularly effective in patients with severe preoperative DDH, although the results also suggested a limitation in the applicability of PAO for these patients.

The association between aging factor and auto graft bone remodeling was studied in 48 cases who had been operated for lumber radiculopathy or canal stenosis. PLF was carried out for all cases. We made 4 indexes as follows:1) end-time when resorption for graft bone stopped.2) radiodensity peak-time of graft bone.3) iso-radiodensity time between graft bone and neighbouring bone tissue.4) the time when range of movement decreased to below 3 or 2 degrees at PLF level.Our study indicated that resorption of graft bone ended within 6-8 months after operation, iso-radiodensity time for graft bone was gradually lengthened as aging or bone density mass decreased, and bone union was also delayed.

Fibrous dysplasia of the femoral neck is a serious clinical problem because structural stability is destroyed.We experienced treating four patients with monostotic fibrous dysplasia of the femoral neck. One of the patients was male and three were female, whose ages were 16 to 41 years. Two patients were treated with curettage of lesions of fibrous dysplasia and autogenous cancellous bone-grafting, together with vascular bundle transpla ntation. One patient was treated with curettage and cortical bone-grafting, and the other with corrective osteotomy for coxa vara after a pathological fracture.In the treatment of symptomatic fibrous dysplasia several surgical approaches have been uesd with varying success. Curettage and autogenous cancellous bone-grafting are used primarily as a means of filling small defects and inducing bone formation. But radical excision is being abandoned, since it is now recognized that removal of all dysplastic tissue is not needed to achieve a satisfactory result. So autogenous cortical bone is chosen for reconstructing large defects that require strength and is used primarily as supporting struts. When a symptomatic deformity is continued, corrective osteotomy is indicated to obtain normal biomechanical values of the hip.Our treatment plans are as follows;1) prevention of deformity and fracture2) corrective osteotomy for a symptomatic deformity

The cervical spinal cord is at a great risk for injury during traumatic accidents occurring within people of relatively young age. Spinal cord injury can not be easily characterized clinically nor through in vitro testing. An understanding of cervical spinal cord deformation is important for defining an injury threshold of the spinal cord. Therefore, an analytical method may be beneficial for determining the response of the spinal cord response to external loads on the spine. We have developed a three-dimensional, non-linear finite element model to quantify physiologic strains and stresses in the cervical spinal cord placed in the ligamentous C5-C6 motion segment. Compressive loads along with flexion and extension moments were applied to the bony segment and not the cord itself. Motion data, shown in degrees of movement in flexion and extension calculated for the model showed a close representation to in vivo data. Von Mises stress plots and strains on the cervical spinal cord were computed. This model represents a first attempt by the authors to analytically quantify the mechanical response of the spinal cord to cervical spine injury.

Biomechanical analyses under compression, flexion, and extension loading were performed to evaluate the stability of interbody, posterolateral, posterior, and facet fusions using a nonlinear three-dimensional finite element method. The effects of facet fusion on other lumbar fusions were also examined. A three-dimensional L4-L5 motion segment model was developed that took into consideration the material nonlinearities of ligaments and annular fibers and the contact nonlinearities of facet joints. Of all models of fusion, maximum rigidity was obtained in the interbody fusion model. In the posterolateral, posterior, and facet fusion models under compression, axial displacement and flexion rotation were induced. In combination with facet fusion, the interbody, posterolateral, and posterior fusion models demonstrated a decrease in axial displacement of about 6%, 1%, and 5%, respectively, under compression and a decrease in rotation angle of about 22%, 12%, and 48%, respectively, under flexion-extension loading. Stress concentration moved principally toward the fusion site, indicating increased load transfer across the fusion mass. Our findings suggest that a more solid fixation can be expected from lumbar fusion--especially in posterior fusion--if facet fusion is performed.

We established a three-dimensional finite element method (FEM) model of the 4th and 5th vertebrae, using computed tomography (CT) images (2-mm slice thickness) of a healthy 29-year-old man. Because of the lack of specific data regarding the material characteristics of the nucleus pulposus of intervertebral discs, we used intradiscal pressure in the nucleus pulposus to establish the model. We referred to data from Nachemson and from Sato et al. regarding intradiscal pressure and to the methods of Shirazi-Adl for data for other material characteristics (see text for these references). The mid-position model bears a load of 294 N in the vertical direction, while the models of the flexed and extended positions bear loads of 15 N-m. In addition, a degenerative disc model without intradiscal pressure was created for the standing model. The use of these models allowed the investigation of von Mises stress on the vertebral endplates and the annulus fibrosus. We also examined von Mises stress on the facet joint in normal and degenerative disc models. There was increased von Mises stress on the vertebral endplate in the anterior, center portions. von Mises stress on the annulus fibrosus increased in the posterior portion, the entrance to the neural foramen, and the exit of the neural foramen. von Mises stress was greater during flexion in the posterior portion; in particular, increasing to about 1.6 times the level seen with other postures. No changes were observed in von Mises stress on the vertebral endplates or annulus fibrosus in the degenerative disc model, but von Mises stress on the facet joints was about 2.5 times that seen in the normal disc model.

Three patients with cervical disk herniation were studied to evaluate the effectiveness of magnetic resonance imaging with Gd-DTPA. All patients underwent surgery, and it was comfirmed that all disks prolapsed into the epidural space. The early T-weighted spin-echo images were obtained within 10 minutes after contrast material administration. Two cases showed peripheral enhancement of the prolapsed on the early studies, but one case showed no enhancement. Neovascularization occurring at the edge of fibrocartilage fragment was present in one case which showed peripheral enhancement on MR imaging. The mechanism of enhancement of the peridiskal region appears to be related to accumulation of contrast material to epidural fibrosis and neovascularization at the edge of disk fragment.