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12 results on '"Kokawa, Takanori"'

8. Associating the Severity of Emphysema with Coronary Flow Reserve and Left Atrial Conduit Function for the Emphysema Patients with Known or Suspected Coronary Artery Disease

Author

Kubooka, Makiko, primary, Ishida, Masaki, additional, Takafuji, Masafumi, additional, Ito, Haruno, additional, Kokawa, Takanori, additional, Nakamura, Satoshi, additional, Domae, Kensuke, additional, Araki, Suguru, additional, Ichikawa, Yasutaka, additional, Murashima, Shuichi, additional, and Sakuma, Hajime, additional

Published
2024
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9. Microvascular Dysfunction in Patients with Idiopathic Dilated Cardiomyopathy: Quantitative Assessment with Phase Contrast Cine MR Imaging of the Coronary Sinus

Author

Takafuji, Masafumi, primary, Ishida, Masaki, additional, Nakamura, Satoshi, additional, Nakata, Kei, additional, Ito, Haruno, additional, Kokawa, Takanori, additional, Domae, Kensuke, additional, Araki, Suguru, additional, Nakamori, Shiro, additional, Ishiura, Junko, additional, Dohi, Kaoru, additional, and Sakuma, Hajime, additional

Published
2023
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12. Microvascular Dysfunction in Patients with Idiopathic Dilated Cardiomyopathy: Quantitative Assessment with Phase Contrast Cine MR Imaging of the Coronary Sinus.

Author

Takafuji M, Ishida M, Nakamura S, Nakata K, Ito H, Kokawa T, Domae K, Araki S, Nakamori S, Ishiura J, Dohi K, and Sakuma H

Subjects
Humans, Female, Male, Middle Aged, Retrospective Studies, Adult, Coronary Circulation physiology, Aged, Microcirculation, Heart Ventricles diagnostic imaging, Heart Ventricles physiopathology, Heart Ventricles pathology, Microvessels diagnostic imaging, Microvessels physiopathology, Cardiomyopathy, Dilated diagnostic imaging, Cardiomyopathy, Dilated physiopathology, Cardiomyopathy, Dilated complications, Magnetic Resonance Imaging, Cine methods, Coronary Sinus diagnostic imaging, Coronary Sinus physiopathology
Abstract

Purpose: The purposes of this study were to compare global coronary flow reserve (CFR) between patients with idiopathic dilated cardiomyopathy (DCM) and risk-matched controls using cardiac MRI (CMR), and to evaluate the relationship between global CFR and CMR left ventricular (LV) parameters., Methods: Twenty-six patients with DCM and 26 risk-matched controls who underwent comprehensive CMR examination, including stress-rest coronary sinus flow measurement by phase contrast (PC) cine CMR were retrospectively studied. LV peak global longitudinal, radial, and circumferential strains (GLS, GRS, and GCS) were determined by feature tracking., Results: Patients with DCM had significantly lower global CFR compared with the risk-matched controls (2.87 ± 0.86 vs. 4.03 ± 1.47, P = 0.001). Among the parameters, univariate linear regression analyses revealed significant correlation of global CFR with LV end-diastolic volume index (r = -0.396, P = 0.045), LV mass index (r = -0.461, P = 0.018), GLS (r = -0.558, P = 0.003), and GRS (r = 0.392, P = 0.047). Multiple linear regression analysis revealed GLS as the only independent predictor of global CFR (standardized β = -0.558, P = 0.003)., Conclusion: Global CFR was significantly impaired in patients with idiopathic DCM and independently associated with LV GLS, suggesting that microvascular dysfunction may contribute to deterioration of LV function in patients with idiopathic DCM.

Published
2025
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