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32 results on '"Kolar, Patrik"'

1. International network of cancer genome projects

Author

Hudson (Chairperson), Thomas J, Anderson, Warwick, Aretz, Axel, Barker, Anna D, Bell, Cindy, Bernabé, Rosa R, Bhan, MK, Calvo, Fabien, Eerola, Iiro, Gerhard, Daniela S, Guttmacher, Alan, Guyer, Mark, Hemsley, Fiona M, Jennings, Jennifer L, Kerr, David, Klatt, Peter, Kolar, Patrik, Kusuda, Jun, Lane, David P, Laplace, Frank, Lu, Youyong, Nettekoven, Gerd, Ozenberger, Brad, Peterson, Jane, Rao, TS, Remacle, Jacques, Schafer, Alan J, Shibata, Tatsuhiro, Stratton, Michael R, Vockley, Joseph G, Watanabe, Koichi, Yang, Huanming, Yuen, Matthew MF, Knoppers (Leader), Bartha M, Bobrow, Martin, Cambon-Thomsen, Anne, Dressler, Lynn G, Dyke, Stephanie OM, Joly, Yann, Kato, Kazuto, Kennedy, Karen L, Nicolás, Pilar, Parker, Michael J, Rial-Sebbag, Emmanuelle, Romeo-Casabona, Carlos M, Shaw, Kenna M, Wallace, Susan, Wiesner, Georgia L, Zeps, Nikolajs, Lichter (Leader), Peter, Biankin, Andrew V, Chabannon, Christian, Chin, Lynda, Clément, Bruno, de Alava, Enrique, Degos, Françoise, Ferguson, Martin L, Geary, Peter, Hayes, D Neil, Hudson, Thomas J, Johns, Amber L, Kasprzyk, Arek, Nakagawa, Hidewaki, Penny, Robert, Piris, Miguel A, Sarin, Rajiv, Scarpa, Aldo, van de Vijver, Marc, Futreal (Leader), P Andrew, Aburatani, Hiroyuki, Bayés, Mónica, Bowtell, David DL, Campbell, Peter J, Estivill, Xavier, Grimmond, Sean M, Gut, Ivo, Hirst, Martin, López-Otín, Carlos, Majumder, Partha, Marra, Marco, McPherson, John D, Ning, Zemin, Puente, Xose S, Ruan, Yijun, Stunnenberg, Hendrik G, Swerdlow, Harold, Velculescu, Victor E, Wilson, Richard K, Xue, Hong H, Yang, Liu, Spellman (Leader), Paul T, Bader, Gary D, Boutros, Paul C, and Flicek, Paul

Subjects
Cancer, Genetics, Human Genome, DNA Methylation, DNA Mutational Analysis, Databases, Genetic, Genes, Neoplasm, Genetics, Medical, Genome, Human, Genomics, Humans, Intellectual Property, International Cooperation, Mutation, Neoplasms, International Cancer Genome Consortium, General Science & Technology
Abstract

The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.

Published
2010

2. International network of cancer genome projects.

Author

International Cancer Genome Consortium, Hudson, Thomas J, Anderson, Warwick, Artez, Axel, Barker, Anna D, Bell, Cindy, Bernabé, Rosa R, Bhan, MK, Calvo, Fabien, Eerola, Iiro, Gerhard, Daniela S, Guttmacher, Alan, Guyer, Mark, Hemsley, Fiona M, Jennings, Jennifer L, Kerr, David, Klatt, Peter, Kolar, Patrik, Kusada, Jun, Lane, David P, Laplace, Frank, Youyong, Lu, Nettekoven, Gerd, Ozenberger, Brad, Peterson, Jane, Rao, TS, Remacle, Jacques, Schafer, Alan J, Shibata, Tatsuhiro, Stratton, Michael R, Vockley, Joseph G, Watanabe, Koichi, Yang, Huanming, Yuen, Matthew MF, Knoppers, Bartha M, Bobrow, Martin, Cambon-Thomsen, Anne, Dressler, Lynn G, Dyke, Stephanie OM, Joly, Yann, Kato, Kazuto, Kennedy, Karen L, Nicolás, Pilar, Parker, Michael J, Rial-Sebbag, Emmanuelle, Romeo-Casabona, Carlos M, Shaw, Kenna M, Wallace, Susan, Wiesner, Georgia L, Zeps, Nikolajs, Lichter, Peter, Biankin, Andrew V, Chabannon, Christian, Chin, Lynda, Clément, Bruno, de Alava, Enrique, Degos, Françoise, Ferguson, Martin L, Geary, Peter, Hayes, D Neil, Johns, Amber L, Kasprzyk, Arek, Nakagawa, Hidewaki, Penny, Robert, Piris, Miguel A, Sarin, Rajiv, Scarpa, Aldo, van de Vijver, Marc, Futreal, P Andrew, Aburatani, Hiroyuki, Bayés, Mónica, Botwell, David DL, Campbell, Peter J, Estivill, Xavier, Grimmond, Sean M, Gut, Ivo, Hirst, Martin, López-Otín, Carlos, Majumder, Partha, Marra, Marco, McPherson, John D, Ning, Zemin, Puente, Xose S, Ruan, Yijun, Stunnenberg, Hendrik G, Swerdlow, Harold, Velculescu, Victor E, Wilson, Richard K, Xue, Hong H, Yang, Liu, Spellman, Paul T, Bader, Gary D, and Boutros, Paul C

Subjects
International Cancer Genome Consortium, Humans, Neoplasms, DNA Mutational Analysis, Genetics, Medical, Genomics, DNA Methylation, Mutation, Genome, Human, International Cooperation, Intellectual Property, Databases, Genetic, Genes, Neoplasm, Genetics, Medical, Genome, Human, Databases, Genetic, Genes, Neoplasm, General Science & Technology
Abstract

The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.

Published
2010

3. 'Omics Data Sharing

Author

Field, Dawn, Sansone, Susanna-Assunta, Collis, Amanda, Booth, Tim, Dukes, Peter, Gregurick, Susan K., Kennedy, Karen, Kolar, Patrik, Kolker, Eugene, Maxon, Mary, Millard, Siân, Mugabushaka, Alexis-Michel, Perrin, Nicola, Remade, Jacques E., Remington, Karin, Rocca-Serra, Philippe, Taylor, Chris F., Thorley, Mark, Tiwari, Bela, and Wilbanks, John

Published
2009
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4. ʼOmics Data Sharing

Author

Field, Dawn, Sansone, Susanna-Assunta, Collis, Amanda, Booth, Tim, Dukes, Peter, Gregurick, Susan K., Kennedy, Karen, Kolar, Patrik, Kolker, Eugene, Maxon, Mary, Millard, Siân, Mugabushaka, Alexis-Michel, Perrin, Nicola, Remacle, Jacques E., Remington, Karin, Rocca-Serra, Philippe, Taylor, Chris F., Thorley, Mark, Tiwari, Bela, and Wilbanks, John

Published
2009

5. Report on EU–USA Workshop: How Systems Biology Can Advance Cancer Research (27 October 2008)

Author

Aebersold, Ruedi, Auffray, Charles, Baney, Erin, Barillot, Emmanuel, Brazma, Alvis, Brett, Catherine, Brunak, Søren, Butte, Atul, Califano, Andrea, Celis, Julio, Čufer, Tanja, Ferrell, James, Galas, David, Gallahan, Daniel, Gatenby, Robert, Goldbeter, Albert, Hace, Nataša, Henney, Adriano, Hood, Lee, Iyengar, Ravi, Jackson, Vicky, Kallioniemi, Ollie, Klingmüller, Ursula, Kolar, Patrik, Kolch, Walter, Kyriakopoulou, Christina, Laplace, Frank, Lehrach, Hans, Marcus, Frederick, Matrisian, Lynn, Nolan, Garry, Pelkmans, Lucas, Potti, Anil, Sander, Chris, Seljak, Marija, Singer, Dinah, Sorger, Peter, Stunnenberg, Hendrik, Superti-Furga, Giulio, Uhlen, Mathias, Vidal, Marc, Weinstein, John, Wigle, Dennis, Williams, Michael, Wolkenhauer, Olaf, Zhivotovsky, Boris, Zinovyev, Andrei, and Zupan, Blaž

Published
2009
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8. Recommendations for Mass Spectrometry Data Quality Metrics for Open Access Data (Corollary to the Amsterdam Principles)

Author

Kinsinger, Christopher R., Apffel, James, Baker, Mark, Bian, Xiaopeng, Borchers, Christoph H., Bradshaw, Ralph, Brusniak, Mi-Youn, Chan, Daniel W., Deutsch, Eric W., Domon, Bruno, Gorman, Jeff, Grimm, Rudolf, Hancock, William, Hermjakob, Henning, Horn, David, Hunter, Christie, Kolar, Patrik, Kraus, Hans-Joachim, Langen, Hanno, Linding, Rune, Moritz, Robert L., Omenn, Gilbert S., Orlando, Ron, Pandey, Akhilesh, Ping, Peipei, Rahbar, Amir, Rivers, Robert, Seymour, Sean L., Simpson, Richard J., Slotta, Douglas, Smith, Richard D., Stein, Stephen E., Tabb, David L., Tagle, Danilo, Yates, John R., III, Rodriguez, Henry, Kinsinger, Christopher R., Apffel, James, Baker, Mark, Bian, Xiaopeng, Borchers, Christoph H., Bradshaw, Ralph, Brusniak, Mi-Youn, Chan, Daniel W., Deutsch, Eric W., Domon, Bruno, Gorman, Jeff, Grimm, Rudolf, Hancock, William, Hermjakob, Henning, Horn, David, Hunter, Christie, Kolar, Patrik, Kraus, Hans-Joachim, Langen, Hanno, Linding, Rune, Moritz, Robert L., Omenn, Gilbert S., Orlando, Ron, Pandey, Akhilesh, Ping, Peipei, Rahbar, Amir, Rivers, Robert, Seymour, Sean L., Simpson, Richard J., Slotta, Douglas, Smith, Richard D., Stein, Stephen E., Tabb, David L., Tagle, Danilo, Yates, John R., III, and Rodriguez, Henry

Abstract

Policies supporting the rapid and open sharing of proteomic data are being implemented by the leading journals in the field. The proteomics community is taking steps to ensure that data are made publicly accessible and are of high quality, a challenging task that requires the development and deployment of methods for measuring and documenting data quality metrics. On September 18, 2010, the United States National Cancer Institute convened the "International Workshop on Proteomic Data Quality Metrics" in Sydney, Australia, to identify and address issues facing the development and use of such methods for open access proteomics data. The stakeholders at the workshop enumerated the key principles underlying a framework for data quality assessment in mass spectrometry data that will meet the needs of the research community, journals, funding agencies, and data repositories. Attendees discussed and agreed up on two primary needs for the wide use of quality metrics: 1) an evolving list of comprehensive quality metrics and 2) standards accompanied by software analytics. Attendees stressed the importance of increased education and training programs to promote reliable protocols in proteomics. This workshop report explores the historic precedents, key discussions, and necessary next steps to enhance the quality of open access data. By agreement, this article is published simultaneously in the Journal of Proteome Research, Molecular and Cellular Proteomics, Proteomics, and Proteomics Clinical Applications as a public service to the research community. The peer review process was a coordinated effort conducted by a panel of referees selected by the journals.

Published
2011

9. International network of cancer genome projects

Author

Hudson, Thomas J., Anderson, Warwick, Aretz, Axel, Barker, Anna D., Bell, Cindy, Bernabe, Rosa R., Bhan, M. K., Calvo, Fabien, Eerola, Iiro, Gerhard, Daniela S., Guttmacher, Alan, Guyer, Mark, Hemsley, Fiona M., Jennings, Jennifer L., Kerr, David, Klatt, Peter, Kolar, Patrik, Kusuda, Jun, Lane, David P., Laplace, Frank, Lu, Youyong, Nettekoven, Gerd, Ozenberger, Brad, Peterson, Jane, Rao, T. S., Remacle, Jacques, Schafer, Alan J., Shibata, Tatsuhiro, Stratton, Michael R., Vockley, Joseph G., Watanabe, Koichi, Yang, Huanming, Yuen, Matthew M. F., Knoppers, M., Bobrow, Martin, Cambon-Thomsen, Anne, Dressler, Lynn G., Dyke, Stephanie O. M., Joly, Yann, Kato, Kazuto, Kennedy, Karen L., Nicolas, Pilar, Parker, Michael J., Rial-Sebbag, Emmanuelle, Romeo-Casabona, Carlos M., Shaw, Kenna M., Wallace, Susan, Wiesner, Georgia L., Zeps, Nikolajs, Lichter, Peter, Biankin, Andrew V., Chabannon, Christian, Chin, Lynda, Clement, Bruno, de Alava, Enrique, Degos, Francoise, Ferguson, Martin L., Geary, Peter, Hayes, D. Neil, Johns, Amber L., Nakagawa, Hidewaki, Penny, Robert, Piris, Miguel A., Sarin, Rajiv, Scarpa, Aldo, van de Vijver, Marc, Futreal, P. Andrew, Aburatani, Hiroyuki, Bayes, Monica, Bowtell, David D. L., Campbell, Peter J., Estivill, Xavier, Grimmond, Sean M., Gut, Ivo, Hirst, Martin, Lopez-Otin, Carlos, Majumder, Partha, Marra, Marco, Ning, Zemin, Puente, Xose S., Ruan, Yijun, Stunnenberg, Hendrik G., Swerdlow, Harold, Velculescu, Victor E., Wilson, Richard K., Xue, Hong H., Yang, Liu, Spellman, Paul T., Bader, Gary D., Boutros, Paul C., Flicek, Paul, Getz, Gad, Guigo, Roderic, Guo, Guangwu, Haussler, David, Heath, Simon, Hubbard, Tim J., Jiang, Tao, Jones, Steven M., Li, Qibin, Lopez-Bigas, Nuria, Luo, Ruibang, Pearson, John V., Quesada, Victor, Raphael, Benjamin J., Sander, Chris, Speed, Terence P., Stuart, Joshua M., Teague, Jon W., Totoki, Yasushi, Tsunoda, Tatsuhiko, Valencia, Alfonso, Wheeler, David A., Wu, Honglong, Zhao, Shancen, Zhou, Guangyu, Stein, Lincoln D., Lathrop, Mark, Ouellette, B. F. Francis, Thomas, Gilles, Yoshida, Teruhiko, Axton, Myles, Gunter, Chris, McPherson, John D., Miller, Linda J., Kasprzyk, Arek, Zhang, Junjun, Haider, Syed A., Wang, Jianxin, Yung, Christina K., Cros, Anthony, Liang, Yong, Gnaneshan, Saravanamuttu, Guberman, Jonathan, Hsu, Jack, Chalmers, Don R. C., Hasel, Karl W., Kaan, Terry S. H., Knoppers, Bartha M., Lowrance, William W., Masui, Tohru, Rodriguez, Laura Lyman, Vergely, Catherine, Cloonan, Nicole, Defazio, Anna, Eshleman, James R., Etemadmoghadam, Dariush, Gardiner, Brooke B., Kench, James G., Sutherland, Robert L., Tempero, Margaret A., Waddell, Nicola J., Wilson, Peter J., Gallinger, Steve, Tsao, Ming-Sound, Shaw, Patricia A., Petersen, Gloria M., Mukhopadhyay, Debabrata, DePinho, Ronald A., Thayer, Sarah, Muthuswamy, Lakshmi, Shazand, Kamran, Beck, Timothy, Sam, Michelle, Timms, Lee, Ballin, Vanessa, Ji, Jiafu, Zhang, Xiuqing, Chen, Feng, Hu, Xueda, Yang, Qi, Tian, Geng, Zhang, Lianhai, Xing, Xiaofang, Li, Xianghong, Zhu, Zhenggang, Yu, Yingyan, Yu, Jun, Tost, Joerg, Brennan, Paul, Holcatova, Ivana, Zaridze, David, Brazma, Alvis, Egevad, Lars, Prokhortchouk, Egor, Banks, Rosamonde Elizabeth, Uhlén, Mathias, Viksna, Juris, Pontén, Fredrik, Skryabin, Konstantin, Birney, Ewan, Borg, Ake, Borresen-Dale, Anne-Lise, Caldas, Carlos, Foekens, John A., Martin, Sancha, Reis-Filho, Jorge S., Richardson, Andrea L., Sotiriou, Christos, van't Veer, Laura, Birnbaum, Daniel, Blanche, Helene, Boucher, Pascal, Boyault, Sandrine, Masson-Jacquemier, Jocelyne D., Pauporte, Iris, Pivot, Xavier, Vincent-Salomon, Anne, Tabone, Eric, Theillet, Charles, Treilleux, Isabelle, Bioulac-Sage, Paulette, Decaens, Thomas, Franco, Dominique, Gut, Marta, Samuel, Didier, Zucman-Rossi, Jessica, Eils, Roland, Brors, Benedikt, Korbel, Jan O., Korshunov, Andrey, Landgraf, Pablo, Lehrach, Hans, Pfister, Stefan, Radlwimmer, Bernhard, Reifenberger, Guido, Taylor, Michael D., von Kalle, Christof, Majumder, Partha P., Pederzoli, Paolo, Lawlor, Rita T., Delledonne, Massimo, Bardelli, Alberto, Gress, Thomas, Klimstra, David, Zamboni, Giuseppe, Nakamura, Yusuke, Miyano, Satoru, Fujimoto, Akihiro, Campo, Elias, de Sanjose, Silvia, Montserrat, Emili, Gonzalez-Diaz, Marcos, Jares, Pedro, Himmelbauer, Heinz, Bea, Silvia, Aparicio, Samuel, Easton, Douglas F., Collins, Francis S., Compton, Carolyn C., Lander, Eric S., Burke, Wylie, Green, Anthony R., Hamilton, Stanley R., Kallioniemi, Olli P., Ley, Timothy J., Liu, Edison T., Wainwright, Brandon J., Hudson, Thomas J., Anderson, Warwick, Aretz, Axel, Barker, Anna D., Bell, Cindy, Bernabe, Rosa R., Bhan, M. K., Calvo, Fabien, Eerola, Iiro, Gerhard, Daniela S., Guttmacher, Alan, Guyer, Mark, Hemsley, Fiona M., Jennings, Jennifer L., Kerr, David, Klatt, Peter, Kolar, Patrik, Kusuda, Jun, Lane, David P., Laplace, Frank, Lu, Youyong, Nettekoven, Gerd, Ozenberger, Brad, Peterson, Jane, Rao, T. S., Remacle, Jacques, Schafer, Alan J., Shibata, Tatsuhiro, Stratton, Michael R., Vockley, Joseph G., Watanabe, Koichi, Yang, Huanming, Yuen, Matthew M. F., Knoppers, M., Bobrow, Martin, Cambon-Thomsen, Anne, Dressler, Lynn G., Dyke, Stephanie O. M., Joly, Yann, Kato, Kazuto, Kennedy, Karen L., Nicolas, Pilar, Parker, Michael J., Rial-Sebbag, Emmanuelle, Romeo-Casabona, Carlos M., Shaw, Kenna M., Wallace, Susan, Wiesner, Georgia L., Zeps, Nikolajs, Lichter, Peter, Biankin, Andrew V., Chabannon, Christian, Chin, Lynda, Clement, Bruno, de Alava, Enrique, Degos, Francoise, Ferguson, Martin L., Geary, Peter, Hayes, D. Neil, Johns, Amber L., Nakagawa, Hidewaki, Penny, Robert, Piris, Miguel A., Sarin, Rajiv, Scarpa, Aldo, van de Vijver, Marc, Futreal, P. Andrew, Aburatani, Hiroyuki, Bayes, Monica, Bowtell, David D. L., Campbell, Peter J., Estivill, Xavier, Grimmond, Sean M., Gut, Ivo, Hirst, Martin, Lopez-Otin, Carlos, Majumder, Partha, Marra, Marco, Ning, Zemin, Puente, Xose S., Ruan, Yijun, Stunnenberg, Hendrik G., Swerdlow, Harold, Velculescu, Victor E., Wilson, Richard K., Xue, Hong H., Yang, Liu, Spellman, Paul T., Bader, Gary D., Boutros, Paul C., Flicek, Paul, Getz, Gad, Guigo, Roderic, Guo, Guangwu, Haussler, David, Heath, Simon, Hubbard, Tim J., Jiang, Tao, Jones, Steven M., Li, Qibin, Lopez-Bigas, Nuria, Luo, Ruibang, Pearson, John V., Quesada, Victor, Raphael, Benjamin J., Sander, Chris, Speed, Terence P., Stuart, Joshua M., Teague, Jon W., Totoki, Yasushi, Tsunoda, Tatsuhiko, Valencia, Alfonso, Wheeler, David A., Wu, Honglong, Zhao, Shancen, Zhou, Guangyu, Stein, Lincoln D., Lathrop, Mark, Ouellette, B. F. Francis, Thomas, Gilles, Yoshida, Teruhiko, Axton, Myles, Gunter, Chris, McPherson, John D., Miller, Linda J., Kasprzyk, Arek, Zhang, Junjun, Haider, Syed A., Wang, Jianxin, Yung, Christina K., Cros, Anthony, Liang, Yong, Gnaneshan, Saravanamuttu, Guberman, Jonathan, Hsu, Jack, Chalmers, Don R. C., Hasel, Karl W., Kaan, Terry S. H., Knoppers, Bartha M., Lowrance, William W., Masui, Tohru, Rodriguez, Laura Lyman, Vergely, Catherine, Cloonan, Nicole, Defazio, Anna, Eshleman, James R., Etemadmoghadam, Dariush, Gardiner, Brooke B., Kench, James G., Sutherland, Robert L., Tempero, Margaret A., Waddell, Nicola J., Wilson, Peter J., Gallinger, Steve, Tsao, Ming-Sound, Shaw, Patricia A., Petersen, Gloria M., Mukhopadhyay, Debabrata, DePinho, Ronald A., Thayer, Sarah, Muthuswamy, Lakshmi, Shazand, Kamran, Beck, Timothy, Sam, Michelle, Timms, Lee, Ballin, Vanessa, Ji, Jiafu, Zhang, Xiuqing, Chen, Feng, Hu, Xueda, Yang, Qi, Tian, Geng, Zhang, Lianhai, Xing, Xiaofang, Li, Xianghong, Zhu, Zhenggang, Yu, Yingyan, Yu, Jun, Tost, Joerg, Brennan, Paul, Holcatova, Ivana, Zaridze, David, Brazma, Alvis, Egevad, Lars, Prokhortchouk, Egor, Banks, Rosamonde Elizabeth, Uhlén, Mathias, Viksna, Juris, Pontén, Fredrik, Skryabin, Konstantin, Birney, Ewan, Borg, Ake, Borresen-Dale, Anne-Lise, Caldas, Carlos, Foekens, John A., Martin, Sancha, Reis-Filho, Jorge S., Richardson, Andrea L., Sotiriou, Christos, van't Veer, Laura, Birnbaum, Daniel, Blanche, Helene, Boucher, Pascal, Boyault, Sandrine, Masson-Jacquemier, Jocelyne D., Pauporte, Iris, Pivot, Xavier, Vincent-Salomon, Anne, Tabone, Eric, Theillet, Charles, Treilleux, Isabelle, Bioulac-Sage, Paulette, Decaens, Thomas, Franco, Dominique, Gut, Marta, Samuel, Didier, Zucman-Rossi, Jessica, Eils, Roland, Brors, Benedikt, Korbel, Jan O., Korshunov, Andrey, Landgraf, Pablo, Lehrach, Hans, Pfister, Stefan, Radlwimmer, Bernhard, Reifenberger, Guido, Taylor, Michael D., von Kalle, Christof, Majumder, Partha P., Pederzoli, Paolo, Lawlor, Rita T., Delledonne, Massimo, Bardelli, Alberto, Gress, Thomas, Klimstra, David, Zamboni, Giuseppe, Nakamura, Yusuke, Miyano, Satoru, Fujimoto, Akihiro, Campo, Elias, de Sanjose, Silvia, Montserrat, Emili, Gonzalez-Diaz, Marcos, Jares, Pedro, Himmelbauer, Heinz, Bea, Silvia, Aparicio, Samuel, Easton, Douglas F., Collins, Francis S., Compton, Carolyn C., Lander, Eric S., Burke, Wylie, Green, Anthony R., Hamilton, Stanley R., Kallioniemi, Olli P., Ley, Timothy J., Liu, Edison T., and Wainwright, Brandon J.

Abstract

The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies., QC 20110114

Published
2010
Full Text
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10. Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy : the Amsterdam principles.

Author

Rodriguez, Henry, Snyder, Mike, Uhlén, Mathias, Andrews, Phil, Beavis, Ronald, Borchers, Christoph, Chalkley, Robert J, Cho, Sang Yun, Cottingham, Katie, Dunn, Michael, Dylag, Tomasz, Edgar, Ron, Hare, Peter, Heck, Albert J R, Hirsch, Roland F, Kennedy, Karen, Kolar, Patrik, Kraus, Hans-Joachim, Mallick, Parag, Nesvizhskii, Alexey, Ping, Peipei, Pontén, Fredrik, Yang, Liming, Yates, John R, Stein, Stephen E, Hermjakob, Henning, Kinsinger, Christopher R, Apweiler, Rolf, Rodriguez, Henry, Snyder, Mike, Uhlén, Mathias, Andrews, Phil, Beavis, Ronald, Borchers, Christoph, Chalkley, Robert J, Cho, Sang Yun, Cottingham, Katie, Dunn, Michael, Dylag, Tomasz, Edgar, Ron, Hare, Peter, Heck, Albert J R, Hirsch, Roland F, Kennedy, Karen, Kolar, Patrik, Kraus, Hans-Joachim, Mallick, Parag, Nesvizhskii, Alexey, Ping, Peipei, Pontén, Fredrik, Yang, Liming, Yates, John R, Stein, Stephen E, Hermjakob, Henning, Kinsinger, Christopher R, and Apweiler, Rolf

Abstract

Policies supporting the rapid and open sharing of genomic data have directly fueled the accelerated pace of discovery in large-scale genomics research. The proteomics community is starting to implement analogous policies and infrastructure for making large-scale proteomics data widely available on a precompetitive basis. On August 14, 2008, the National Cancer Institute (NCI) convened the "International Summit on Proteomics Data Release and Sharing Policy" in Amsterdam, The Netherlands, to identify and address potential roadblocks to rapid and open access to data. The six principles agreed upon by key stakeholders at the summit addressed issues surrounding (1) timing, (2) comprehensiveness, (3) format, (4) deposition to repositories, (5) quality metrics, and (6) responsibility for proteomics data release. This summit report explores various approaches to develop a framework of data release and sharing principles that will most effectively fulfill the needs of the funding agencies and the research community.

Published
2009
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11. A convenient synthesis of the tetrasubstituted pyrrole: an undergraduate heterocyclic laboratory experiment

Author

Kolar, Patrik and Tisler, Miha

Subjects
Amino acids -- Research, Chemistry, Organic -- Study and teaching, Organic compounds -- Synthesis, Chemistry, Education, Science and technology
Abstract

A simple and quick synthesis of tetrasubstituted pyrrole can replace the classical pyrrole syntheses for demonstrating amino acid chemistry in introductory or advanced organic chemistry. This experiment exposes students to the use of amino acids as heterocycle synthons without the long-reaction times required for most amino acid derivative cyclizations to generate pyrroles. Experiment procedures are provided.

Published
1996

12. Recommendations for mass spectrometry data quality metrics for open access data (corollary to the Amsterdam principles)

Author

Kinsinger, Christopher R., primary, Apffel, James, additional, Baker, Mark, additional, Bian, Xiaopeng, additional, Borchers, Christoph H., additional, Bradshaw, Ralph, additional, Brusniak, Mi-Youn, additional, Chan, Daniel W., additional, Deutsch, Eric W., additional, Domon, Bruno, additional, Gorman, Jeff, additional, Grimm, Rudolf, additional, Hancock, William, additional, Hermjakob, Henning, additional, Horn, David, additional, Hunter, Christie, additional, Kolar, Patrik, additional, Kraus, Hans-Joachim, additional, Langen, Hanno, additional, Linding, Rune, additional, Moritz, Robert L., additional, Omenn, Gilbert S., additional, Orlando, Ron, additional, Pandey, Akhilesh, additional, Ping, Peipei, additional, Rahbar, Amir, additional, Rivers, Robert, additional, Seymour, Sean L., additional, Simpson, Richard J., additional, Slotta, Douglas, additional, Smith, Richard D., additional, Stein, Stephen E., additional, Tabb, David L., additional, Tagle, Danilo, additional, Yates, John R., additional, and Rodriguez, Henry, additional

Published
2011
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14. Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy: The Amsterdam Principles

Author

Rodriguez, Henry, primary, Snyder, Mike, additional, Uhlén, Mathias, additional, Andrews, Phil, additional, Beavis, Ronald, additional, Borchers, Christoph, additional, Chalkley, Robert J., additional, Cho, Sang Yun, additional, Cottingham, Katie, additional, Dunn, Michael, additional, Dylag, Tomasz, additional, Edgar, Ron, additional, Hare, Peter, additional, Heck, Albert J. R., additional, Hirsch, Roland F., additional, Kennedy, Karen, additional, Kolar, Patrik, additional, Kraus, Hans-Joachim, additional, Mallick, Parag, additional, Nesvizhskii, Alexey, additional, Ping, Peipei, additional, Pontén, Fredrik, additional, Yang, Liming, additional, Yates, John R., additional, Stein, Stephen E., additional, Hermjakob, Henning, additional, Kinsinger, Christopher R., additional, and Apweiler, Rolf, additional

Published
2009
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15. Report on EU-USA Workshop: How Systems Biology Can Advance Cancer Research (27 October 2008)

Author

Aebersold, Ruedi, primary, Auffray, Charles, additional, Baney, Erin, additional, Barillot, Emmanuel, additional, Brazma, Alvis, additional, Brett, Catherine, additional, Brunak, Søren, additional, Butte, Atul, additional, Califano, Andrea, additional, Celis, Julio, additional, Čufer, Tanja, additional, Ferrell, James, additional, Galas, David, additional, Gallahan, Daniel, additional, Gatenby, Robert, additional, Goldbeter, Albert, additional, Hace, Nataša, additional, Henney, Adriano, additional, Hood, Lee, additional, Iyengar, Ravi, additional, Jackson, Vicky, additional, Kallioniemi, Ollie, additional, Klingmüller, Ursula, additional, Kolar, Patrik, additional, Kolch, Walter, additional, Kyriakopoulou, Christina, additional, Laplace, Frank, additional, Lehrach, Hans, additional, Marcus, Frederick, additional, Matrisian, Lynn, additional, Nolan, Garry, additional, Pelkmans, Lucas, additional, Potti, Anil, additional, Sander, Chris, additional, Seljak, Marija, additional, Singer, Dinah, additional, Sorger, Peter, additional, Stunnenberg, Hendrik, additional, Superti-Furga, Giulio, additional, Uhlen, Mathias, additional, Vidal, Marc, additional, Weinstein, John, additional, Wigle, Dennis, additional, Williams, Michael, additional, Wolkenhauer, Olaf, additional, Zhivotovsky, Boris, additional, Zinovyev, Andrei, additional, and Zupan, Blaž, additional

Published
2008
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23. Recommendations for Mass Spectrometry Data Quality Metrics for Open Access Data (Corollary to the Amsterdam Principles).

Author

Kinsinger, Christopher R., Apffel, James, Baker, Mark, Bian, Xiaopeng, Borchers, Christoph H., Bradshaw, Ralph, Brusniak, Mi-Youn, Chan, Daniel W., Deutsch, Eric W., Domon, Bruno, Gorman, Jeff, Grimm, Rudolf, Hancock, William, Hermjakob, Henning, Horn, David, Hunter, Christie, Kolar, Patrik, Kraus, Hans-Joachim, Langen, Hanno, and Linding, Rune

Published
2012
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27. Asymmetric Steering of Oxa Diels–Alder Reactions with Silyloxydienes Employing Proline Esters as Chiral Auxiliary Groups

Author

Bläser, Edwin, Kolar, Patrik, Fenske, Dieter, and Goesmann, Hellmut

Abstract

Chiral aldehydes 4a,b, obtained by the ozonolysis of the corresponding N,N'-fumaroylbis[(S)-proline esters] 3 react in the presence of lanthanoid chelate complexes Eu(fod)3 or Eu(hfc)3 with silyloxydienes 7 or 12 to give δ-lactones 10 or dihydro-γ-pyrones 13 with very high diastereomeric ratios (up to 99:1). The absolute configuration of the predominating diastereoisomer of compound 10b was unequivocally determined by X-ray structural analysis.

Published
1999
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28. International network of cancer genome projects

Author

Laplace, Frank, Calvo, Fabien, Bernabé, Rosa R., Nettekoven, Gerd, Schafer, Alan J., Bell, Cindy, Remacle, Jacques, Yang, Huanming, Jennings, Jennifer L., Rao, T.S., Guyer, Mark, Kerr, David, Kusuda, Jun, Guttmacher, Alan, Stratton, Michael R., Hemsley, Fiona M., Barker, Anna D., Klatt, Peter, Aretz, Axel, Kolar, Patrik, Shibata, Tatsuhiro, Hudson (Chairperson), Thomas J., Lane, David P., Ozenberger, Brad, Eerola, Iiro, Vockley, Joseph G., Anderson, Warwick, Bhan, M. K., Lu, Youyong, Gerhard, Daniela S., Watanabe, Koichi, and Peterson, Jane

Subjects
3. Good health
Abstract

The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumors from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of over 25,000 cancer genomes at the genomic, epigenomic, and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically-relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.

29. Future food research and innovation under Horizon 2020 (2014 - 2020).

Author

Kolar, Patrik and Kammenou, Maria

Subjects
FOOD research, INTERNATIONAL alliances, INTERNATIONAL cooperation, CONSUMER behavior, WASTE management, FOOD chains
Abstract

The author indicates the success of previous EU (European Union) Framework Programmes (FP) and summaries the future food research and innovation activities under the EU FP, "Horizon 2020". Topics discussed include success of multidisciplinary consortia in bringing significant advances in the food research sector, international co-operation as an essential priority for Horizon 2020 and better understanding of business and consumer behavior for reducing waste at all stages of the food chain.

Published
2014

32. Recommendations for mass spectrometry data quality metrics for open access data (corollary to the Amsterdam principles).

Author

Kinsinger CR, Apffel J, Baker M, Bian X, Borchers CH, Bradshaw R, Brusniak MY, Chan DW, Deutsch EW, Domon B, Gorman J, Grimm R, Hancock W, Hermjakob H, Horn D, Hunter C, Kolar P, Kraus HJ, Langen H, Linding R, Moritz RL, Omenn GS, Orlando R, Pandey A, Ping P, Rahbar A, Rivers R, Seymour SL, Simpson RJ, Slotta D, Smith RD, Stein SE, Tabb DL, Tagle D, Yates JR, and Rodriguez H

Subjects
Benchmarking methods, Benchmarking standards, Guidelines as Topic, Research Design, Access to Information, Mass Spectrometry methods, Mass Spectrometry standards, Proteomics education, Proteomics methods, Proteomics standards
Abstract

Policies supporting the rapid and open sharing of proteomic data are being implemented by the leading journals in the field. The proteomics community is taking steps to ensure that data are made publicly accessible and are of high quality, a challenging task that requires the development and deployment of methods for measuring and documenting data quality metrics. On September 18, 2010, the U.S. National Cancer Institute (NCI) convened the "International Workshop on Proteomic Data Quality Metrics" in Sydney, Australia, to identify and address issues facing the development and use of such methods for open access proteomics data. The stakeholders at the workshop enumerated the key principles underlying a framework for data quality assessment in mass spectrometry data that will meet the needs of the research community, journals, funding agencies, and data repositories. Attendees discussed and agreed upon two primary needs for the wide use of quality metrics: (i) an evolving list of comprehensive quality metrics and (ii) standards accompanied by software analytics. Attendees stressed the importance of increased education and training programs to promote reliable protocols in proteomics. This workshop report explores the historic precedents, key discussions, and necessary next steps to enhance the quality of open access data. By agreement, this article is published simultaneously in Proteomics, Proteomics Clinical Applications, Journal of Proteome Research, and Molecular and Cellular Proteomics, as a public service to the research community. The peer review process was a coordinated effort conducted by a panel of referees selected by the journals., (Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2012
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