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Copyright of Zeitschrift für Rheumatologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Zusammenfassung: Hintergrund: Geschlechtsunterschiede in Diagnostik und Therapie verschiedenster Erkrankungen werden zunehmend erforscht mit dem Ziel, Therapiestrategien zu optimieren und den individuellen Behandlungserfolg zu verbessern. Method: ik: In dieser Arbeit wird die bestehende Literatur zu geschlechtsspezifischen Unterschieden bei entzündlich-rheumatischen Erkrankungen zusammengefasst. Ergebnisse: Viele, aber nicht alle entzündlich-rheumatischen Erkrankungen treten häufiger bei Frauen als bei Männern auf. Frauen haben oft eine längere Beschwerdedauer bis zur Diagnosestellung als Männer, was durch unterschiedliche klinische und radiologische Erscheinungsbilder verursacht sein kann. Frauen haben krankheitsübergreifend häufiger niedrigere Remissions- und Therapieansprechraten in Bezug auf die antirheumatische Medikation als Männer, auch Therapieabbrüche sind bei Frauen häufiger als bei Männern. Ob Frauen vermehrt Anti-drug-Antikörper gegen biologische Antirheumatika entwickeln, ist noch unklar. Bei Januskinaseinhibitoren gibt es bislang keine Hinweise auf ein unterschiedliches Therapieansprechen. Schlussfolgerung: Ob auch in der Rheumatologie individuelle Dosierungsschemata und geschlechtsangepasste Therapieziele nötig sind, kann aus der bisherigen Evidenz nicht abgeleitet werden. [ABSTRACT FROM AUTHOR]

Copyright of Zeitschrift für Rheumatologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Zeitschrift für Rheumatologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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