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Hyalohyphomycosis includes infections caused by various fungal species that produce hyaline, septate, branched hyphae. Fusarium is one such species which usually causes multiple papulo-nodules, ecthyma gangrenosum-like ulcers in immunocompromised individuals. Also, fusariosis is usually difficult to manage and responds favorably to amphotericin B, voriconazole, and posaconazole in disseminated cases. Here, we report an atypical case of cutaneous fusariosis in an immunocompetent individual who presented with multiple large cystic swellings, psoriasiform plaques, and palmoplantar keratoderma, and the patient responded completely to itraconazole. [ABSTRACT FROM AUTHOR]

Herpes simplex virus (HSV) is known to influence the course of pemphigus vulgaris. Relapse, exacerbation, and treatment resistance in patients with pemphigus vulgaris can be due to HSV infection. To characterize the clinical markers of HSV infection among patients with pemphigus. This was a hospital-based, descriptive study performed with 60 consecutive patients with pemphigus vulgaris. The clinical and laboratory features of patients with documented HSV infection were then compared with those of patients without infection. HSV infection was confirmed in 23 (38.33%) patients. On univariate analysis, it was noted that male sex (P =.03); presence of fissures (P =.001), hemorrhagic crusts (P =.003), erosions with angulated margins (P =.024), and linear erosions (P =.001); and raised erythrocyte sedimentation rate (P =.015) were found to be significantly associated with HSV infection. In a multivariate analysis, hemorrhagic crusts (P =.015) and linear erosions (P =.008) were found to be independent predictors of HSV infection. We did not use polymerase chain reaction to detect HSV infection, which could have yielded more cases of HSV infection. In the clinical setting of pemphigus vulgaris, the presence of fissures, hemorrhagic crusts, linear erosions, erosions with angulated margins and raised erythrocyte sedimentation rate must alert the clinician to the possibility of HSV superinfection. [ABSTRACT FROM AUTHOR]

Byline: Deepthi. Konda, Devinder. Thappa Aging is an inevitable biological process and not a disease. The desire to maintain a beautiful, youthful appearance crosses all racial, cultural, and economic barriers, [...]

Byline: Deepthi. Konda, Devinder. Thappa Introduction 'Mesotherapy' is a non-surgical, minimally invasive method of drug delivery that consists of multiple intradermal or subcutaneous injections of a mixture of compounds 'melange' [...]

A letter to the editor is presented discussing the case of a 6-month-old child highlighting the presentation of chikungunya in an infant in the form of vesiculobullous lesions, suggesting that chikungunya be included in the differential diagnosis of febrile vesiculobullous eruption in infants.

Competing Interests: There are no conflicts of interest.