337 results on '"Kopito, Ron R."'
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2. Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
3. The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation
4. Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1
5. Small molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states
6. The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation
7. Ribosomal protein RPL26 is the principal target of UFMylation
8. Proteomic analysis of monolayer-integrated proteins on lipid droplets identifies amphipathic interfacial α-helical membrane anchors
9. The Mammalian Endoplasmic Reticulum-Associated Degradation System
10. Unassembled CD147 is an endogenous endoplasmic reticulum–associated degradation substrate
11. Defining human ERAD networks through an integrative mapping strategy
12. Increased Susceptibility of Cytoplasmic over Nuclear Polyglutamine Aggregates to Autophagic Degradation
13. Formation of Morphologically Similar Globular Aggregates from Diverse Aggregation-Prone Proteins in Mammalian Cells
14. RPL26/uL24 UFMylation is essential for ribosome-associated quality control at the endoplasmic reticulum
15. Specificity in Intracellular Protein Aggregation and Inclusion Body Formation
16. Impairment of the Ubiquitin-Proteasome System by Protein Aggregation
17. Formation of High Molecular Weight Complexes of Mutant Cu,Zn-Superoxide Dismutase in a Mouse Model for Familial Amyotrophic Lateral Sclerosis
18. Methods for genetic analysis of mammalian ER-associated degradation
19. Aggresomes: A Cellular Response to Misfolded Proteins
20. A non‐canonical scaffold‐type E3 ligase complex mediates protein UFMylation
21. Parallel CRISPR-Cas9 screens reveal mechanisms of PLIN2 and lipid droplet regulation
22. PEX19 Coordinates Neutral Lipid Storage in Cells in a Peroxisome-Independent Fashion
23. Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover
24. Non canonical scaffold-type ligase complex mediates protein UFMylation
25. Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection
26. Ubiquitination of Integral Membrane Proteins and Proteins in the Secretory Pathway
27. Hypothalamic Neurodegeneration and Adult-Onset Obesity in Mice Lacking the Ubb Polyubiquitin Gene
28. Functional Activation of Plasma Membrane Anion Exchangers Occurs in a Pre-Golgi Compartment
29. Cloning and Characterization of Band 3, the Human Erythrocyte Anion-Exchange Protein (AE1)
30. Functional Expression and Subcellular Localization of an Anion Exchanger Cloned from Choroid Plexus
31. Multiple Tissue-Specific Sites of Transcriptional Initiation of the Mouse Anion Antiport Gene in Erythroid and Renal Cells
32. Global changes to the ubiquitin system in Huntington's disease
33. Live-Cell Imaging of Ubiquitin–Proteasome System Function
34. Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses
35. Author response: Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses
36. Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses
37. Acute unfolding of a single protein immediately stimulates recruitment of ubiquitin protein ligase E3C (UBE3C) to 26S proteasomes
38. Biosynthesis and degradation of CFTR
39. Application and Analysis of the GFPu Family of Ubiquitin‐Proteasome System Reporters
40. Cytosolic pH regulates GCL through control of phosphorylation states of CFTR
41. ER quality control: the cytoplasmic connection
42. A cluster of cytoplasmic histidine residues specifies pH dependence of the AE2 plasma membrane anion exchanger
43. (R)-mevalonate Excretion in Human and Rat Urines
44. Degradation of CFTR by the ubiquitin-proteasome pathway
45. Conformational states of CFTR associated with channel gating: the role of ATP binding and hydrolysis
46. Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis
47. Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation
48. Molecular Biology of the Anion Exchanger Gene Family
49. Small-molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states
50. Parallel genome-wide CRISPR analysis identifies a role for heterotypic ubiquitin chains in ER-associated degradation
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