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Your search keyword '"Kosaka, Michiya"' showing total 22 results
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22 results on '"Kosaka, Michiya"'

6. Facelift Incision for Parotidectomy

Author

Kosaka, Michiya, primary, Ohue, Tetsuo, additional, Tanimoto, Kazunori, additional, Orita, Saeko, additional, Orita, Yorihisa, additional, Maeta, Manabu, additional, and Nishizaki, Kazunori, additional

Published
2004
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16. Increased Urinary Excretion of Macrophage-Colony-Stimulating Factor (M-CSF) in Patients with IgA Nephropathy: Tonsil Stimulation Enhances Urinary M-CSF Excretion

Author

Matsuda, Mitsuhiro, primary, Shikata, Kenichi, additional, Wada, Jun, additional, Yamaji, Hiroaki, additional, Shikata, Yasushi, additional, Doi, Akira, additional, Kosaka, Michiya, additional, Akagi, Hirofumi, additional, Masuda, Yu, additional, Ohmoto, Yasukazu, additional, and Makino, Hirofumi, additional

Published
1999
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21. Prognosis of Tonsillectomy in Patients with IgA Nephropathy.

Author

Akagi, Hirofumi, Nishizaki, Kazunori, Hattori, Kenshi, Kosaka, Michiya, Fukushima, Kunihiro, Doi, Akira, and Masuda, Yu

Subjects
TONSILLECTOMY, KIDNEY diseases
Abstract

IgA nephropathy (IgAN) is a type of chronic glomerulonephritis characterized by IgA deposits mainly in the mesangial area. It does not have so favourable a prognosis as was initially thought. This nephropathy is one of the diseases affected by tonsillar focal infections, and there have been patients in whom tonsillectomy has been effective. In this study, 24 patients with IgAN were followed for more than 2 years after tonsillectomy and studied clinicopathologically. Remission of proteinuria was observed in 41.7% of the patients 6 months after surgery and in 50.0% 2 years after surgery. At 2 years after surgery, patients with minor and focal segmental renal lesions showed a significantly higher rate of remission of proteinuria than patients with diffuse renal lesions. There was no statistically significant difference between positive and negative patients in the rate of remission of proteinuria based on any parameter of the tonsillar provocation test at any time after surgery. [ABSTRACT FROM AUTHOR]

Published
1999
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22. Role of macrophage migration inhibitory factor in otitis media with effusion in adults.

Author

Kariya S, Okano M, Aoji K, Kosaka M, Chikumoto E, Hattori H, Yuen K, Nishioka S, Nishioka K, and Nishizaki K

Subjects
Adult, Age Factors, Aged, Aged, 80 and over, Chemokine CCL5 analysis, Endotoxins analysis, Female, Humans, Interleukin-1 analysis, Macrophage Migration-Inhibitory Factors analysis, Male, Middle Aged, Otitis Media with Effusion etiology, Tumor Necrosis Factor-alpha analysis, Macrophage Migration-Inhibitory Factors physiology, Otitis Media with Effusion immunology
Abstract

Otitis media with effusion (OME) is one of the most common ear diseases. Bacterial endotoxins and several inflammatory cytokines appear to be involved in the pathogenesis of OME in children; however, little is known of the immunological aspects of the onset of OME in adults. We sought to determine the presence of macrophage migration inhibitory factor (MIF) as well as interleukin 1beta (IL-1beta), tumor necrosis factor alpha (TNF-alpha), RANTES (regulated upon activation, normal T-cell expressed and presumably secreted), and endotoxin in middle ear effusions (MEEs) from adult patients with OME. In addition, the levels of MIF in MEEs from adults and children were compared. MEE was obtained from 95 adults and 11 children. The levels of MIF, IL-1beta, TNF-alpha, and RANTES were determined by enzyme-linked immunosorbent assay, and the concentrations of endotoxin and total protein were determined by the Endospec assay and bicinchoninic acid assay, respectively. MIF was detected in 97.9% of the MEEs from adults, while endotoxin, IL-1beta, TNF-alpha, and RANTES were detected in 96.8, 12.6, 5.3, and 43.9%, respectively. In addition, the level of MIF was significantly higher than those of endotoxin, IL-1beta, and TNF-alpha. A positive correlation between the levels of MIF and endotoxin was observed. MIF and endotoxin were detected in 81.8 and 72.7%, respectively, of the MEEs from the children. The level of MIF was significantly higher in the children, and conversely that of endotoxin was significantly higher in the adults. These results suggest that the interaction between MIF and endotoxin may promote fluid collection in the middle ear, particularly in adults.

Published
2003
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