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149 results on '"Koshkina, Olga"'

1. Surface Properties of Colloidal Particles Affect Colloidal Self-Assembly in Evaporating Self-Lubricating Ternary Droplets

Author

Koshkina, Olga, Raju, Lijun Thayyil, Kaltbeitzel, Anke, Riedinger, Andreas, Lohse, Detlef, Zhang, Xuehua, and Landfester, Katharina

Subjects
Condensed Matter - Soft Condensed Matter, Physics - Fluid Dynamics
Abstract

In this work, we unravel the role of surface properties of colloidal particles on the formation of supraparticles (clusters of colloidal particles) in a colloidal Ouzo droplet. Self-lubricating colloidal Ouzo droplets are an efficient and simple approach to form supraparticles, overcoming the challenge of the coffee stain effect in situ. Supraparticles are an efficient route to high-performance materials in various fields, from catalysis to carriers for therapeutics. Yet, the role of the surface of colloidal particles in the formation of supraparticles using Ouzo droplets remains unknown. Therefore, we used silica particles as a model system and compared sterically stabilized versus electrostatically stabilized silica particles - positively and negatively charged. Additionally, we studied the effect of hydration. Hydrated negatively charged silica particles and sterically stabilized silica particles form supraparticles. Conversely, dehydrated negatively charged silica particles and positively charged amine-coated particles form flat film-like deposits. Notably, the assembly process is different for all the four types of particles. The surface modifications alter (a) the contact line motion of the Ouzo droplet and (b) the particle-oil and particle-substrate interactions. These alterations modify the particle accumulation at the various interfaces, which ultimately determines the shape of the final deposit. Thus, by modulating the surface properties of the colloidal particles, we can tune the shape of the final deposit, from a spheroidal supraparticle to a flat deposit. In the future, this approach can be used to tailor the supraparticles for applications such as optics and catalysis, where the shape affects the functionality., Comment: 38 pages, 9 figures

Published
2022
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5. Selective footprints and genes relevant to cold adaptation and other phenotypic traits are unscrambled in the genomes of divergently selected chicken breeds

Author

Romanov, Michael N., Abdelmanova, Alexandra S., Fisinin, Vladimir I., Gladyr, Elena A., Volkova, Natalia A., Koshkina, Olga A., Rodionov, Andrey N., Vetokh, Anastasia N., Gusev, Igor V., Anshakov, Dmitry V., Stanishevskaya, Olga I., Dotsev, Arsen V., Griffin, Darren K., and Zinovieva, Natalia A.

Published
2023
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10. Genome-Wide Insights into Intraspecific Taxonomy and Genetic Diversity of Argali (Ovis ammon)

Author

Dotsev, Arsen, primary, Koshkina, Olga, additional, Kharzinova, Veronika, additional, Deniskova, Tatiana, additional, Reyer, Henry, additional, Kunz, Elisabeth, additional, Mészáros, Gábor, additional, Shakhin, Alexey, additional, Petrov, Sergey, additional, Medvedev, Dmitry, additional, Kuksin, Alexander, additional, Bat-Erdene, Ganchimeg, additional, Munkhtsog, Bariushaa, additional, Bagirov, Vugar, additional, Wimmers, Klaus, additional, Sölkner, Johann, additional, Medugorac, Ivica, additional, and Zinovieva, Natalia, additional

Published
2023
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12. List of contributors

Author

Lin, Kuo-Shyan, primary, Afonin, Sergii, additional, Bailey, Justin J., additional, Barrio, Pablo, additional, Benard, Francois, additional, Bernard-Gauthier, Vadim, additional, Billard, Thierry, additional, Buscemi, Silvestre, additional, Caillé, Fabien, additional, Chêne, Loïc P., additional, Delbrouck, Julien A., additional, Dykstra, Kevin D., additional, El Qacemi, Myriem, additional, Fitz, Lori, additional, Fustero, Santos, additional, Graton, Jéôme, additional, Gutbrod, Oliver, additional, Honda, Tadashi, additional, Hunter, Luke, additional, Ichiishi, Naoko, additional, Jeschke, Peter, additional, Jurkschat, Klaus, additional, Komarov, Igor V., additional, Koshkina, Olga, additional, Krska, Shane W., additional, Kuhnast, Bertrand, additional, Le Questel, Jean-Yves, additional, Leroux, Frederic R., additional, Liger, François, additional, Linclau, Bruno, additional, Maienfisch, Peter, additional, Mansour, Flora, additional, Müller, Klaus, additional, Murphy, Cormac D., additional, Ojima, Iwao, additional, Pace, Andrea, additional, Palmer-Brown, William, additional, Palumbo Piccionello, Antonio, additional, Perrin, David M., additional, Pertusati, Fabrizio, additional, Pibiri, Ivana, additional, Pileggi, Elisa, additional, Quinn, Laura, additional, Rendine, Stefano, additional, Richardson, Paul F., additional, Roche, Mélanie, additional, Román, Raquel, additional, Saccomanno, Marta, additional, Schirrmacher, Ralf, additional, Schirrmacher, Esther, additional, Sedgwick, Daniel M., additional, Serpi, Michaela, additional, Specklin, Simon, additional, Srinivas, Mangala, additional, Staal, Xander, additional, Trabanco, Andrés A., additional, Ulrich, Anne S., additional, Verdurand, Mathieu, additional, Vincent, Stéphane P., additional, Wängler, Carmen, additional, Wängler, Björn, additional, and Xing, Li, additional

Published
2019
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15. Real-time 31P NMR reveals different gradient strengths in polyphosphoester copolymers as potential MRI-traceable nanomaterials.

Author

Rheinberger, Timo, Flögel, Ulrich, Koshkina, Olga, and Wurm, Frederik R.

Subjects
COPOLYMERS, MAGNETIC resonance imaging, PHOSPHONATES, FIREPROOFING agents, NANOSTRUCTURED materials, TISSUE engineering, COPOLYMERIZATION
Abstract

Polyphosphoesters (PPEs) are used in tissue engineering and drug delivery, as polyelectrolytes, and flame-retardants. Mostly polyphosphates have been investigated but copolymers involving different PPE subclasses have been rarely explored and the reactivity ratios of different cyclic phospholanes have not been reported. We synthesized binary and ternary PPE copolymers using cyclic comonomers, including side-chain phosphonates, phosphates, thiophosphate, and in-chain phosphonates, through organocatalyzed ring-opening copolymerization. Reactivity ratios were determined for all cases, including ternary PPE copolymers, using different nonterminal models. By combining different comonomers and organocatalysts, we created gradient copolymers with adjustable amphiphilicity and microstructure. Reactivity ratios ranging from 0.02 to 44 were observed for different comonomer sets. Statistical ring-opening copolymerization enabled the synthesis of amphiphilic gradient copolymers in a one-pot procedure, exhibiting tunable interfacial and magnetic resonance imaging (MRI) properties. These copolymers self-assembled in aqueous solutions, 31 P MRI imaging confirmed their potential as MRI-traceable nanostructures. This systematic study expands the possibilities of PPE-copolymers for drug delivery and theranostics. Polyphosphoesters (PPEs) are versatile polymers utilized in tissue engineering, as electrolytes, or flame retardants, but copolymers of different PPE subclasses are hardly explored. Here, the authors report general protocols for the organocatalyzed copolymerization of four different PPE subclasses, resulting in copolymers with varying amphiphilicity and gradient strength. [ABSTRACT FROM AUTHOR]

Published
2023
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21. Surface Properties of Colloidal Particles Affect Colloidal Self-Assembly in Evaporating Self-Lubricating Ternary Droplets

Author

Koshkina, Olga, Raju, Lijun Thayyil, Kaltbeitzel, Anke, Riedinger, Andreas, Lohse, Detlef, Zhang, Xuehua, Landfester, Katharina, Max Planck Center, Sustainable Polymer Chemistry, Physics of Fluids, and MESA+ Institute

Subjects
Fluid Dynamics (physics.flu-dyn), UT-Hybrid-D, Colloidal self-assembly, FOS: Physical sciences, Supraparticles, Physics - Fluid Dynamics, Ouzo effect, 02 engineering and technology, Condensed Matter - Soft Condensed Matter, Self-lubrication, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Silica particles, 0104 chemical sciences, 3. Good health, Soft Condensed Matter (cond-mat.soft), General Materials Science, Colloidal stabilization, Evaporation induced self-assembly, 0210 nano-technology, Research Article
Abstract

In this work, we unravel the role of surface properties of colloidal particles on the formation of supraparticles (clusters of colloidal particles) in a colloidal Ouzo droplet. Self-lubricating colloidal Ouzo droplets are an efficient and simple approach to form supraparticles, overcoming the challenge of the coffee stain effect in situ. Supraparticles are an efficient route to high-performance materials in various fields, from catalysis to carriers for therapeutics. Yet, the role of the surface of colloidal particles in the formation of supraparticles using Ouzo droplets remains unknown. Therefore, we used silica particles as a model system and compared sterically stabilized versus electrostatically stabilized silica particles - positively and negatively charged. Additionally, we studied the effect of hydration. Hydrated negatively charged silica particles and sterically stabilized silica particles form supraparticles. Conversely, dehydrated negatively charged silica particles and positively charged amine-coated particles form flat film-like deposits. Notably, the assembly process is different for all the four types of particles. The surface modifications alter (a) the contact line motion of the Ouzo droplet and (b) the particle-oil and particle-substrate interactions. These alterations modify the particle accumulation at the various interfaces, which ultimately determines the shape of the final deposit. Thus, by modulating the surface properties of the colloidal particles, we can tune the shape of the final deposit, from a spheroidal supraparticle to a flat deposit. In the future, this approach can be used to tailor the supraparticles for applications such as optics and catalysis, where the shape affects the functionality., 38 pages, 9 figures

Published
2021

22. Biodegradable polyphosphoester micelles act as both background-free 31P magnetic resonance imaging agents and drug nanocarriers.

Author

Koshkina, Olga, Rheinberger, Timo, Flocke, Vera, Windfelder, Anton, Bouvain, Pascal, Hamelmann, Naomi M., Paulusse, Jos M. J., Gojzewski, Hubert, Flögel, Ulrich, and Wurm, Frederik R.

Subjects
MAGNETIC resonance imaging, NANOCARRIERS, POLYMER colloids, MICELLES, BLOCK copolymers, MOLECULAR structure, POLYMERS
Abstract

In vivo monitoring of polymers is crucial for drug delivery and tissue regeneration. Magnetic resonance imaging (MRI) is a whole-body imaging technique, and heteronuclear MRI allows quantitative imaging. However, MRI agents can result in environmental pollution and organ accumulation. To address this, we introduce biocompatible and biodegradable polyphosphoesters, as MRI-traceable polymers using the 31P centers in the polymer backbone. We overcome challenges in 31P MRI, including background interference and low sensitivity, by modifying the molecular environment of 31P, assembling polymers into colloids, and tailoring the polymers' microstructure to adjust MRI-relaxation times. Specifically, gradient-type polyphosphonate-copolymers demonstrate improved MRI-relaxation times compared to homo- and block copolymers, making them suitable for imaging. We validate background-free imaging and biodegradation in vivo using Manduca sexta. Furthermore, encapsulating the potent drug PROTAC allows using these amphiphilic copolymers to simultaneously deliver drugs, enabling theranostics. This first report paves the way for polyphosphoesters as background-free MRI-traceable polymers for theranostic applications. MRI agents can result in environmental pollution and organ accumulation. Here, the authors show that modifying the molecular structure of biodegradable polyphosphoesters and tailoring the polymers' microstructure to adjust MRI relaxation times can overcome challenges in 31P MR imaging. [ABSTRACT FROM AUTHOR]

Published
2023
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25. Process evaluation for the adaptation, testing and dissemination of a mobile health platform to support people with HIV and tuberculosis in Irkutsk, Siberia

Author

Hodges, Jacqueline, primary, Waldman, Ava Lena, additional, Koshkina, Olga, additional, Suzdalnitsky, Alexey, additional, Schwendinger, Jason, additional, Vitko, Serhiy, additional, Plenskey, Alexey, additional, Plotnikova, Yulia, additional, Moiseeva, Elena, additional, Koshcheyev, Mikhail, additional, Sebekin, Sergey, additional, Zhdanova, Svetlana, additional, Ogarkov, Oleg, additional, Heysell, Scott, additional, and Dillingham, Rebecca, additional

Published
2022
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27. Combination of Multiple Microsatellite Analysis and Genome-Wide SNP Genotyping Helps to Solve Wildlife Crime: A Case Study of Poaching of a Caucasian tur (Capra caucasica) in Russian Mountain National Park

Author

Rodionov, Andrey, primary, Deniskova, Tatiana, additional, Dotsev, Arsen, additional, Volkova, Valeria, additional, Petrov, Sergey, additional, Kharzinova, Veronika, additional, Koshkina, Olga, additional, Abdelmanova, Alexandra, additional, Solovieva, Anastasia, additional, Shakhin, Alexey, additional, Bardukov, Nikolay, additional, and Zinovieva, Natalia, additional

Published
2021
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31. Encapsulation of Paramagnetic Chelates in Perfluorocarbon-loaded Fractal Nanoparticles Enables Modulation of Fluorine-19 and Proton Magnetic Resonance Imaging Signal

Author

Verbeelen, Margot, primary, White, Paul, additional, Staal, Alexander H.J., additional, Swider-Cios, Edyta, additional, Cortenbach, Kimberly R.G., additional, van Riessen, N. Koen, additional, Cadiou, Cyril, additional, Chuburu, Françoise, additional, Srinivas, Mangala, additional, and Koshkina, Olga, additional

Published
2021
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33. Implementation of a Mobile Health Strategy to Improve Linkage to and Engagement with HIV Care for People Living with HIV, Tuberculosis, and Substance Use in Irkutsk, Siberia

Author

Hodges, Jacqueline, primary, Zhdanova, Svetlana, additional, Koshkina, Olga, additional, Suzdalnitsky, Alexey, additional, Waldman, Ava Lena, additional, Schwendinger, Jason, additional, Vitko, Serhiy, additional, Plenskey, Alexey, additional, Plotnikova, Yulia, additional, Moiseeva, Elena, additional, Koshcheyev, Mikhail, additional, Sebekin, Sergey, additional, Ogarkov, Oleg, additional, Dillingham, Rebecca, additional, and Heysell, Scott, additional

Published
2021
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39. Urine colorimetry for levofloxacin pharmacokinetics and personalized dosing in people with drug-resistant tuberculosis

Author

Heysell, ScottK, primary, Rao, Prakruti, additional, Zhdanova, Svetlana, additional, Ogarkov, Oleg, additional, Orlova, Elizaveta, additional, Ebers, Andrew, additional, Stroup, Suzanne, additional, Mirawdaly, Shino, additional, Aartsen, DanielVan, additional, Koshkina, Olga, additional, Suzdalnitsky, Alexey, additional, Moiseeva, Elena, additional, and Dillingham, Rebecca, additional

Published
2020
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40. Multicore liquid perfluorocarbon-loaded multimodal nanoparticles for stable ultrasound and 19 F MRI applied to in vivo cell tracking

Author

Koshkina, Olga, Lajoinie, Guillaume, Baldelli Bombelli, Francesca, Swider, Edyta, Cruz, Luis J., White, Paul B., Schweins, Ralf, Dolen, Yusuf, van Dinther, Eric A.W., van Riessen, N. Koen, Rogers, Sarah E., Fokkink, Remco, Voets, Ilja K., van Eck, Ernst R.H., Heerschap, Arend, Versluis, Michel, de Korte, Chris L., Figdor, Carl G., de Vries, I. Jolanda M., Srinivas, Mangala, Koshkina, Olga, Lajoinie, Guillaume, Baldelli Bombelli, Francesca, Swider, Edyta, Cruz, Luis J., White, Paul B., Schweins, Ralf, Dolen, Yusuf, van Dinther, Eric A.W., van Riessen, N. Koen, Rogers, Sarah E., Fokkink, Remco, Voets, Ilja K., van Eck, Ernst R.H., Heerschap, Arend, Versluis, Michel, de Korte, Chris L., Figdor, Carl G., de Vries, I. Jolanda M., and Srinivas, Mangala

Abstract

Ultrasound is the most commonly used clinical imaging modality. However, in applications requiring cell-labeling, the large size and short active lifetime of ultrasound contrast agents limit their longitudinal use. Here, 100 nm radius, clinically applicable, polymeric nanoparticles containing a liquid perfluorocarbon, which enhance ultrasound contrast during repeated ultrasound imaging over the course of at least 48 h, are described. The perfluorocarbon enables monitoring the nanoparticles with quantitative 19 F magnetic resonance imaging, making these particles effective multimodal imaging agents. Unlike typical core–shell perfluorocarbon-based ultrasound contrast agents, these nanoparticles have an atypical fractal internal structure. The nonvaporizing highly hydrophobic perfluorocarbon forms multiple cores within the polymeric matrix and is, surprisingly, hydrated with water, as determined from small-angle neutron scattering and nuclear magnetic resonance spectroscopy. Finally, the nanoparticles are used to image therapeutic dendritic cells with ultrasound in vivo, as well as with 19 F MRI and fluorescence imaging, demonstrating their potential for long-term in vivo multimodal imaging.

Published
2019

41. Multicore Liquid Perfluorocarbon-Loaded Multimodal Nanoparticles for Stable Ultrasound and 19F MRI Applied to In Vivo Cell Tracking

Author

Koshkina, Olga, Lajoinie, Guillaume, Baldelli Bombelli, Francesca, Swider, Edyta, Cruz, Luis J., White, Paul B., Schweins, Ralf, Dolen, Yusuf, van Dinther, Eric A.W., van Riessen, N.K., Rogers, Sarah E., Fokkink, Remco, Voets, Ilja K., van Eck, Ernst R.H., Heerschap, Arend, Versluis, Michel, de Korte, Chris L., Figdor, Carl G., de Vries, I.J.M., Srinivas, Mangala, Koshkina, Olga, Lajoinie, Guillaume, Baldelli Bombelli, Francesca, Swider, Edyta, Cruz, Luis J., White, Paul B., Schweins, Ralf, Dolen, Yusuf, van Dinther, Eric A.W., van Riessen, N.K., Rogers, Sarah E., Fokkink, Remco, Voets, Ilja K., van Eck, Ernst R.H., Heerschap, Arend, Versluis, Michel, de Korte, Chris L., Figdor, Carl G., de Vries, I.J.M., and Srinivas, Mangala

Abstract

Ultrasound is the most commonly used clinical imaging modality. However, in applications requiring cell-labeling, the large size and short active lifetime of ultrasound contrast agents limit their longitudinal use. Here, 100 nm radius, clinically applicable, polymeric nanoparticles containing a liquid perfluorocarbon, which enhance ultrasound contrast during repeated ultrasound imaging over the course of at least 48 h, are described. The perfluorocarbon enables monitoring the nanoparticles with quantitative 19 F magnetic resonance imaging, making these particles effective multimodal imaging agents. Unlike typical core–shell perfluorocarbon-based ultrasound contrast agents, these nanoparticles have an atypical fractal internal structure. The nonvaporizing highly hydrophobic perfluorocarbon forms multiple cores within the polymeric matrix and is, surprisingly, hydrated with water, as determined from small-angle neutron scattering and nuclear magnetic resonance spectroscopy. Finally, the nanoparticles are used to image therapeutic dendritic cells with ultrasound in vivo, as well as with 19 F MRI and fluorescence imaging, demonstrating their potential for long-term in vivo multimodal imaging.

Published
2019

42. Multicore Liquid Perfluorocarbon‐Loaded Multimodal Nanoparticles for Stable Ultrasound and19F MRI Applied to In Vivo Cell Tracking

Author

Koshkina, Olga, primary, Lajoinie, Guillaume, additional, Baldelli Bombelli, Francesca, additional, Swider, Edyta, additional, Cruz, Luis J., additional, White, Paul B., additional, Schweins, Ralf, additional, Dolen, Yusuf, additional, van Dinther, Eric A. W., additional, van Riessen, N. Koen, additional, Rogers, Sarah E., additional, Fokkink, Remco, additional, Voets, Ilja K., additional, van Eck, Ernst R. H., additional, Heerschap, Arend, additional, Versluis, Michel, additional, de Korte, Chris L., additional, Figdor, Carl G., additional, de Vries, I. Jolanda M., additional, and Srinivas, Mangala, additional

Published
2019
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43. Design of triphasic poly(lactic-co-glycolic acid) nanoparticles containing a perfluorocarbon phase for biomedical applications

Author

Swider, Edyta, Staal, Alexander H.J., Van Riessen, N., Jacobs, Linsey, White, Paul B., Fokkink, Remco, Janssen, Geert Jan, Van Dinther, Eric, Figdor, Carl G., De Vries, I.J.M., Koshkina, Olga, Srinivas, Mangala, Swider, Edyta, Staal, Alexander H.J., Van Riessen, N., Jacobs, Linsey, White, Paul B., Fokkink, Remco, Janssen, Geert Jan, Van Dinther, Eric, Figdor, Carl G., De Vries, I.J.M., Koshkina, Olga, and Srinivas, Mangala

Abstract

Poly(lactic-co-glycolic acid) (PLGA) particles are very widely used, particularly for drug delivery, including commercial clinical formulations. Adding perfluorocarbon (PFC) enables in vivo imaging and quantification of the PLGA particles through 19F NMR, MRS or MRI. PFCs are both hydrophobic and lipophobic at the same time. This property makes their encapsulation in particles challenging, as it requires the addition of a third immiscible phase during the emulsification process. Here we explore how different parameters affect the miniemulsion formation of particles loaded with perfluoro-15-crown-5-ether (PFCE). By changing the concentration of surfactant and type of solvent, we were able to control the radius of synthesized particles, between 85-200 nm. We assessed stability and release from the particles at different pH values, showing that hydrophobic agents are released from the particles by diffusion rather than degradation. With cell experiments, we show that primary human dendritic cells take up the particles without any apparent effect, including on cell migration. In summary, the control of synthesis conditions leads to particles with sufficient PFCE encapsulation, which are suitable for drug loading and cell labeling, and do not affect cell viability or functionality. Finally, these nanoparticles can be produced at GMP-grade for clinical use.

Published
2018

44. Urine colorimetry for levofloxacin pharmacokinetics and personalized dosing in people with drug-resistant tuberculosis.

Author

Rao, Prakruti, Zhdanova, Svetlana, Ogarkov, Oleg, Orlova, Elizaveta, Ebers, Andrew, Stroup, Suzanne, Mirawdaly, Shino, Aartsen, Daniel, Koshkina, Olga, Suzdalnitsky, Alexey, Moiseeva, Elena, Dillingham, Rebecca, and Heysell, Scott

Abstract

Background: Levofloxacin is a preferred drug for multidrug-resistant (MDR)-tuberculosis (TB) with bactericidal activity that correlates with the pharmacokinetic exposures of serum peak concentration (Cmax) and total area under the concentration time curve (AUC0-24). Pharmacokinetic exposures can be measured to personalize dosing to reach targets, but this practice requires venepuncture, chromatographic or mass spectrometry equipment, and technical expertise. We sought to demonstrate the accuracy of using urine colorimetry as a more feasible estimation of levofloxacin exposure. Method: A colorimetric method using bromocresol green was tested on spiked urine samples with levofloxacin measured using a spectrophotometer. This method was tested in urine samples of healthy volunteers given one 750 mg dose of levofloxacin with urine collected at 0–4 h, 4–8 h, and 8–24 h intervals, and concomitant serum samples were collected and analyzed by high-performance liquid chromatography. Validation of this assay was done in a cohort of people living with human immunodeficiency virus (PLWH), initiating a levofloxacin containing MDR-TB regimen. Results: Urine colorimetry was reproducible in spiked samples and the calibration was curve linear for levofloxacin concentrations ranging from 7.8 μg/ml to 250 μg/ml, with r = 0.98. In healthy volunteers, correlation between urine absorbance values and serum AUC0-24 was highest in urine collected between 4 and 8 h (r = 0.91, P = 0.01), yet in PLWH, urine collected between 0 and 4 h had highest correlation (r = 0.66, P = 0.05). The area under the receiver operating characteristics curve was >0.8 in the derivation, as well as the validation cohort for the urine absorbance values identifying people with total serum exposure below target. Conclusion: Urine colorimetry was highly sensitive in predicting target serum concentrations. Colorimetric methods to determine levofloxacin in urine may improve the feasibility of therapeutic drug monitoring and personalized dose adjustment in TB endemic settings. [ABSTRACT FROM AUTHOR]

Published
2020
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47. Design of triphasic poly(lactic-co-glycolic acid) nanoparticles containing a perfluorocarbon phase for biomedical applications

Author

Swider, Edyta, primary, Staal, Alexander H. J., additional, Koen van Riessen, N., additional, Jacobs, Linsey, additional, White, Paul B., additional, Fokkink, Remco, additional, Janssen, Geert-Jan, additional, van Dinther, Eric, additional, Figdor, Carl G., additional, de Vries, I. Jolanda M., additional, Koshkina, Olga, additional, and Srinivas, Mangala, additional

Published
2018
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48. Investigation of magnetization reversal in double layer FeNiCo/CoW films

Author

Gavrilyuk, Boris V., Gavrilyuk, Alexander V., and Koshkina, Olga V.

Subjects
Magnetization -- Research, Thin films -- Magnetic properties, Business, Electronics, Electronics and electrical industries
Abstract

The dynamic properties of domain walls in FeNiCo layer dependence on CoW layer thickness have been investigated. The FeNiCo thickness was about 80 nm. While the FeNiCo layer coercivity increases domain wall mobility decreases in weak magnetic fields. The observed mechanism of layers interaction is associated with interaction between FeNiCo domain wall stray fields and CoW layer. The possibility of coercivity increasement without mobility loss has been considered.

Published
1993

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